CN103621550B - A kind of pesticide composition containing cyclazone - Google Patents

Abstract

The invention discloses a pesticide composition containing cyclohexyl flusulfamide, which is a bactericidal composition containing an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from the cyclohexyl flusulfamide, and the active ingredient B is selected from any one of the following compounds: dithianon, fosetyl-aluminum, activated ester, chlorothalonil and captan, wherein the weight ratio of the active ingredient A to the active ingredient B is 1: 70-70: 1. The composition has high activity on various diseases of various crops, has obvious synergistic action and enlarges the bactericidal spectrum. And has the characteristics of small dosage, rain wash resistance and obvious synergy.

Description

A kind of pesticide composition containing cyclazone

technical field

The invention belongs to the technical field of pesticides, and relates to the application of a pesticide composition containing cyclohexasulfame on crop diseases.

technical background

Cyclohexasulfame chemical name: N-(2-trifluoromethyl-4-chlorophenyl)-a-oxocyclohexylsulfonamide. It has strong preventive, therapeutic and osmotic activities, and has high persistence. The field test results show that cyclazone can effectively control Botrytis cinerea, rape sclerotinia, cucumber brown spot and scab.

In the actual process of agricultural production, the most likely problem in disease control is the emergence of disease resistance. Combination of ingredients from different varieties is a common method for controlling resistant diseases. Different ingredients are compounded, and according to the actual application effect, it is judged whether a certain compound is synergistic, additive or antagonistic. In most cases, the compounding effects of pesticides are additive effects, and there are very few compoundings that really have synergistic effects, especially those with very obvious synergistic effects and high synergistic ratios. After research by the inventor, it was found that the combination of cyclazone, dicyanoanthraquinone, aluminum triethylphosphonate, activated ester, chlorothalonil and captan has a good synergistic effect within a certain range. Moreover, there are no related reports about the compounding of cyclazone, dicyanoanthraquinone, aluminum triethylphosphonate, activated esters, chlorothalonil, and captan at present at home and abroad.

Contents of the invention

The object of the present invention is to provide a pesticide composition containing cyclohexasulfame with synergistic effect, low use cost and good control effect.

The present invention is realized through the following technical solutions:

A pesticide composition containing cyclohexasulfame, characterized in that it contains active ingredient A and active ingredient B, the weight ratio of active ingredient A to active ingredient B is 1:70~70:1, and the active ingredient A is selected from Cyclohexasulfame, active ingredient B is selected from any one of the following compounds: dicyanoanthraquinone, aluminum triethylphosphonate, activated ester, chlorothalonil, captan; the preferred weight of active ingredient A and active ingredient B The ratio is 1:50~50:1; more preferably, the weight ratio of cyclazone and dicyanoanthraquinone is 1:15~30:1, and the weight ratio of cyclazone and triethylphosphonate aluminum is 1:30~10:1, the weight ratio of cyclazone to activated ester is 1:10~30:1, the weight ratio of cyclazone to chlorothalonil is 1:25~10:1, The weight ratio of hexasulfame to captan is 1:30~20:1; the most preferred weight ratio of cyclazone to dicyanoanthraquinone is 1:5~10:1, cyclazone The weight ratio of cyclazone to aluminum triethronate is 1:15~5:1, the weight ratio of cyclazone to activated ester is 1:1~20:1, the weight ratio of cyclazone to chlorothalonil The weight ratio of cyclohexasulfame to captan is 1:15~10:1.

The pesticide composition containing cyclohexasulfame is used to prevent and treat crop diseases, and the crops include food crops, bean crops, fiber crops, sugar crops, melon crops, fruit crops, and dried fruit crops , hobby crops, rhizome crops, oil crops, flower crops, medicinal crops, raw material crops, green manure pasture crops; the diseases include gray mold, sclerotinia, brown spot, scab, downy mildew, Leaf mold, powdery mildew, anthracnose, rice blast, sheath blight, canker, blight, blackleg, rust, leaf blight, leaf spot, ring spot, scab, leaf spot.

The content of the active ingredient in the composition of the present invention depends on the application amount when used alone, also depends on the mixing ratio of one compound and another compound and the degree of synergistic effect, and is also related to the target disease. Usually the weight percentage of the active ingredient in the composition is 1%-90% of the total weight, preferably 5%-80%. Depending on the type of preparation, the content range of the active ingredient is different. Usually, liquid preparations contain 1% to 60% by weight of active substances, preferably 5% to 50%; solid preparations contain 5% to 80% by weight of active substances, preferably 10% to 80% %.

The fungicidal composition of the present invention contains at least one surfactant to facilitate the dispersion of active ingredients in water during application. The surfactant content is 2% to 30% of the total weight of the preparation, and the balance is solid or liquid diluent.

The antiseptic composition of the present invention can be diluted or directly used by users before use. Its preparation can be prepared by a common processing method known to those skilled in the art, that is, after the active substance is mixed with a liquid solvent or a solid carrier, and then add a surfactant such as a dispersant, a stabilizer, a wetting agent, a binder, and a defoamer , disintegrants, antifreeze, etc. one or more.

The fungicidal composition of the present invention can be processed into any pesticide-acceptable dosage form as required. Among them, the preferred formulations are wettable powder, water dispersible granule, suspension, suspoemulsion, microemulsion, water emulsion, microcapsule suspension, and microcapsule suspension-suspension. It can also be made into soluble powder.

When the composition is made into wettable powder, it contains the following components and contents: active ingredient A 0.5%~70%, active ingredient B 0.5%~70%, dispersant 1%~12%, wetting agent 1%~8%, Filling allowance.

When the composition is made into water-dispersible granules, it includes the following components and contents: active ingredient A 0.5%~70%, active ingredient B 0.5%~70%, dispersant 1%~12%, wetting agent 1%~8% , Disintegrant 1%~10%, binder 0~8%, filler balance.

When the composition is made into a suspension, it includes the following components and contents: active ingredient A 0.5%~50%, active ingredient B 0.5%~50%, dispersant 1%~10%, wetting agent 1%~10%, disinfectant Foaming agent 0.01%~2%, thickener 0~2%, antifreeze agent 0~8%, deionized water to 100%.

When the composition is made into a suspoemulsion, it includes the following components and contents: active ingredient A 0.5%~50%, active ingredient B 0.5%~50%, emulsifier 1%~10%, dispersant 1%~10%, solvent 1%~20%, defoamer 0.01%~2%, thickener 0~2%, antifreeze 0~8%, deionized water to 100%.

When the composition is made into a microemulsion, it includes the following components and contents: 0.5%~50% of active ingredient A, 0.5%~50% of active ingredient B, 3%~25% of emulsifier, 1%~20% of solvent, anti Freezing agent 0~8%, defoamer 0.01%~2%, deionized water added to 100%.

When the composition is made into water emulsion, it includes the following components and contents: active ingredient A 0.5%~50%, active ingredient B 0.5%~50%, solvent 1%~20%, emulsifier 1%~12%, antifreeze 0~8% of agent, 0.01%~2% of defoamer, 0~2% of thickener, and 100% of deionized water.

When the composition is made into a microcapsule suspension, it includes the following components and contents: active ingredient A 0.5%~50%, active ingredient B 0.5%~50%, polymer capsule wall material 1%~10%, dispersant 2 %~10%, solvent 1%~10%, emulsifier 1%~7%, pH regulator 0.01%~5%, defoamer 0.01%~2%, deionized water to 100%.

When the composition is made into a microcapsule suspension-suspension agent, it includes the following components and contents: 0.5%~50% of active ingredient A, 0.5%~50% of active ingredient B, 1%~12% of polymer capsule wall material, dispersed Agent 1%~12%, wetting agent 1%~8%, solvent 1%~15%, emulsifier 1%~8%, defoamer 0.01%~2%, thickener 0~2%, pH regulator 0.01%~5%, add deionized water to 100%.

Main technical index of wettable powder of the present invention:

Water-dispersible granule main technical index of the present invention:

Suspending agent main technical index of the present invention:

Suspoemulsion main technical index of the present invention:

Microemulsion main technical index of the present invention:

Water-emulsion main technical index of the present invention:

Main technical index of microcapsule suspension of the present invention:

Microcapsule suspension-suspension agent main technical index of the present invention:

The advantages of the present invention are: (1) The composition of the present invention has a good synergistic and long-lasting effect within a certain range, and the control effect is higher than that of a single dose; (2) The dosage of pesticides is reduced, and the residues of pesticides on crops are reduced (3) It has expanded the bactericidal spectrum and has high activity against various diseases.

Detailed ways

The present invention will be further described below in conjunction with the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

Application Example 1

Embodiment 1～14 wettable powder

Mix cyclohexasulfame, active ingredient B, dispersant, wetting agent, and filler, mix evenly in a mixing tank, pulverize through a jet mill and mix evenly, then the wettable powder product of the present invention can be made . See Table 1 for details.

Table 1 Embodiment 1～14 each component and content

Embodiment 15～28 water dispersible granules

Combine cyclohexasulfame, active ingredient B, dispersant, wetting agent, disintegrant, and filler together through airflow pulverization to obtain the required particle size, and then add binder (optional) and other additives to obtain Granulation materials. The water-dispersible granule product of the present invention is obtained by quantitatively sending the material into a fluidized bed granulation dryer for granulation and drying. See Table 2 for details.

Table 2 Embodiment 15～28 each component and content

Embodiment 29～42 suspending agent

Dispersant, wetting agent, thickener (can be added or not), defoamer, antifreeze (can be added or not) are mixed evenly through high-speed shearing, add cyclohexasulfame and active ingredient B, and use Make up the balance with ionized water, and ball mill in a ball mill for 2 to 3 hours, so that the particle size is all below 5 μm, and the suspension product of the present invention is obtained. See Table 3 for details.

Table 3 Embodiment 29～42 each component and content

Embodiment 43～54 suspoemulsion

Mix dispersant, defoamer, thickener (optional), antifreeze (optional), deionized water through high-speed shearing, add cyclohexasulfame, and ball mill in a ball mill for 2 ~3 hours, make the particle size of all the particles below 5 μm to prepare cyclohexasulfame suspension, then directly emulsify the active ingredient B, solvent, emulsifier and various auxiliaries into the suspension with a high-speed stirrer to prepare Obtain the suspoemulsion product of the present invention. See Table 4 and 5 for details.

Table 4 Embodiment 43～48 each component and content

Table 5 Embodiment 49～54 each component and content

The new preparation can be obtained by exchanging dicyanoanthraquinone, aluminum triethylphosphonate, activated ester, chlorothalonil and captan in Table 1 to Table 5.

Embodiment 55～58 water emulsion

Add cyclohexasulfame, active ingredient B, solvent, and emulsifier together to dissolve into a uniform oil phase; add deionized water, antifreeze (optional), thickener (optional) , defoamer mixed together to form a homogeneous water phase. Under high-speed stirring, the water phase is added to the oil phase to prepare the water emulsion product of the present invention. See Table 6 for details.

Table 6 Embodiment 55～58 each component and content

Embodiment 59～61 microemulsion

Dissolve cyclohexasulfame and active ingredient B in a homogenizer with solvent, add emulsifier, antifreeze (optional), and defoamer into the homogenizer with the above solution, Make up the balance with deionized water, then vigorously mix and homogenize, and finally obtain the microemulsion product of the present invention with a clear and transparent appearance. See Table 7 for details.

Table 7 Embodiment 59～61 each component and content

Embodiment 62～64 microcapsule suspension

Mix cyclohexasulfame, active ingredient B, polymer capsule wall material, and solvent to dissolve into a uniform oil phase, and under shearing conditions, add the oil phase to the In the water phase solution of the foaming agent, the balance is made up with deionized water, and the two materials react at the oil-water interface to form a polymer capsule wall to make a well-dispersed microcapsule suspension product of the composition of the present invention. See Table 8 for details.

Table 8 Embodiment 62～64 each component and content

Example 65-67 Microcapsule Suspension - Suspension Concentrate

Mix active ingredient B, polymer capsule wall material, and solvent to dissolve into a uniform oil phase, and add the oil phase to the aqueous phase solution containing emulsifier and pH regulator under shearing conditions to make a well-dispersed microparticle capsule suspension. Dispersant, wetting agent, defoamer, thickener (can be added or not) are mixed evenly by high-speed shearing, add cyclohexasulfame, and ball mill in a ball mill for 2 to 3 hours, so that the particle size of all particles is 5 μm Next, prepare the suspending agent, then add the suspending agent to the aqueous phase solution of the microcapsule suspending agent, make up the balance with deionized water, and make a well-dispersed microcapsule suspension-suspension agent product of the composition of the present invention. See Table 9 for details.

Table 9 Embodiment 65～67 each component and content

The embodiment of the present invention adopts the method combining indoor virulence determination and field test. Firstly, through the indoor toxicity test, the synergistic ratio (SR) of the two agents after compounding in a certain proportion is clarified. SR<0.5 is an antagonistic effect, 0.5≤SR≤1.5 is an additive effect, and SR>1.5 is a synergistic effect. On this basis, field experiments were carried out.

Test method: After pre-testing to determine the effective inhibitory concentration range of each drug, 5 doses of drugs were set according to the content of active ingredients, and water was used as a control. Refer to the "Pesticide Indoor Bioassay Test Guidelines for Fungicides", and use the mycelium growth rate method to determine the toxicity of the pesticides to crop pathogens. After 72 hours, the colony diameter was measured by the cross method, and the net growth and mycelial growth inhibition rate of each treatment were calculated.

Net growth (mm) = measured colony diameter - 5

The mycelial growth inhibition rate was converted into a probability value (y), the concentration of the drug solution (μg/mL) was converted into a logarithmic value (x), and the toxicity regression equation (y=a+bx) was obtained by the least square method, and the This calculates the EC50 value for each agent. At the same time, according to the Wadley method, the synergistic ratio (SR) of the combination of different proportions of the two agents was calculated. SR<0.5 was considered antagonism, 0.5≤SR≤1.5 was additive, and SR>1.5 was synergistic. Calculated as follows:

Where: a and b are the proportions of active ingredient A and active ingredient B in the combination; A is cyclohexasulfame; B is selected from dicyananthraquinone, aluminum triethylphosphonate, activated ester, and chlorothalonil , one of captan.

Application example two:

Tested disease: capsicum anthracnose; test chemicals are provided by Shaanxi Meibang Pesticide Co., Ltd.; test design: through preliminary tests to determine the effective inhibitory concentration of cyclohexasulfame and dicyananthraquinone original drug and the mixture of the two scope.

Toxicity test results

Table 10 Analysis table of toxicity determination results of cyclohexasulfame and dicyanoanthraquinone compounded on capsicum anthracnose

It can be seen from Table 10 that when the compounding ratio of cyclohexasulfame and dicyanoanthraquinone for the prevention and treatment of pepper anthracnose is 1:70~70:1, the synergistic ratio SR is greater than 1.5, indicating that the two are in the range of 1:70~ 70︰1 range of mixing all showed synergistic effect, when the ratio of cyclazone and dicyanoanthraquinone was 1︰15~30︰1, the synergistic effect was more prominent, and the synergistic ratios were greater than 2.20. After testing, it is found that the optimal ratio of cyclazone and dicyananthraquinone is 30:1, 25:1, 20:1, 15:1, 14:1, 13:1, 12:1, 11:1 , 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1 :4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, especially when the weight ratio of cyclazone to dicyananthraquinone is 2:1 When the synergistic ratio is the largest, the synergistic effect is the most obvious.

Application Example Three:

The disease to be tested: cucumber downy mildew; the test chemicals are provided by Shaanxi Meibang Pesticide Co., Ltd.; the test design: through the preliminary test to determine the effectiveness of cyclazone and aluminum triethylphosphonate and the mixture of the two different ratios. Inhibitory concentration range.

Toxicity test results

Table 11 Analysis table of toxicity determination results of cyclohexasulfame and aluminum triethylphosphonate against cucumber downy mildew

It can be seen from Table 11 that when the compounding ratio of cyclohexasulfame and aluminum triethylphosphonate for the control of cucumber downy mildew is 1:70~70:1, the synergistic ratio SR is greater than 1.5, indicating that the two are at 1: 70~70︰1 mixture all showed synergistic effect, when the ratio of cyclohexasulfame and triethylphosphonate aluminum was 1︰30～10︰1, the synergistic effect was more prominent, and the synergistic effect The ratios were all greater than 2.25. After testing, it was found that the optimal ratio of sulfasulfam to aluminum triethronate is 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3: 1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:20, 1:25, 1:30, especially when the weight ratio of cyclazone to aluminum triethronate is 1:4 The effect ratio is the largest, and the synergistic effect is the most obvious.

Application example four:

The disease to be tested: wheat powdery mildew; the test chemicals are provided by Shaanxi Meibang Pesticide Co., Ltd.; the test design: the effective inhibitory concentration range of cyclohexasulfame and active ester raw drug and the mixture of the two in different ratios are determined through preliminary tests.

Toxicity test results

Table 12 Analysis table of toxicity determination results of cyclohexasulfame and activated ester complex to wheat powdery mildew

It can be seen from Table 12 that when the compounding ratio of cyclohexasulfame and activated ester for the control of wheat powdery mildew is 1:70~70:1, the synergistic ratio SR is greater than 1.5, indicating that the two are at 1:70~70: The synergistic effect is shown in the mixture within the range of 1. When the ratio of cyclohexasulfame and activated ester is 1:10~30:1, the synergistic effect is more prominent, and the synergistic ratio is greater than 2.20. After testing, it is found that the optimal ratio of cyclohexasulfame and activated ester is 30:1, 25:1, 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14 :1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1 , 1:1, 1:5, 1:10, especially when the weight ratio of cyclohexasulfame and activated ester is 10:1, the synergistic ratio is the largest and the synergistic effect is the most obvious.

Application embodiment five:

The disease to be tested: Botrytis cinerea; the test chemicals are all provided by Shaanxi Meibang Pesticide Co., Ltd.; the test design: the effective inhibitory concentration range of cyclohexasulfame and chlorothalonil original drug and the mixture of the two in different ratios are determined through preliminary tests .

Toxicity test results

Table 13 Cyclohexasulfame and chlorothalonil complex paired tomato gray mold toxicity analysis table

It can be seen from Table 13 that when the compounding ratio of cyclohexasulfame and chlorothalonil to control tomato gray mold is 1:70~70:1, the synergistic ratio SR is greater than 1.5, indicating that the two ratios are between 1:70~ The synergistic effect was shown in the mixture within the range of 70︰1. When the ratio of cyclohexasulfame and chlorothalonil was 1︰25~10︰1, the synergistic effect was more prominent, and the synergistic ratio was greater than 2.20 . The test found that the optimal ratio of cyclazone to chlorothalonil is 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 2:5, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1: 11. 1:12, 1:13, 1:15, 1:20, 1:25, especially when the weight ratio of cyclazone and chlorothalonil is 2:5, the synergistic ratio is the largest and the synergistic effect is the most obvious.

Application example six:

Tested disease: apple ring spot; test chemicals are provided by Shaanxi Meibang Pesticide Co., Ltd.; test design: the effective inhibitory concentration range of cyclohexasulfame and captan original drug and their different ratio mixtures are determined through preliminary tests .

Toxicity test results

Table 14 Analysis table of the virulence determination results of cyclohexasulfame and captan compound against apple ring spot

It can be seen from Table 14 that when the compounding ratio of cyclohexasulfame and captan to control apple ring spot is 1:70~70:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is greater than 1:70~ In the range of 70︰1, the synergistic effect is shown. When the ratio of cyclazone and captan is 1︰30~20︰1, the synergistic effect is more prominent, and the synergistic ratio is greater than 2.20 . The test found that the optimal ratio of cyclazone and captan is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1: 9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:20, 1:25, 1:30, especially when cyclohexasulfame and captan When the weight ratio is 2:3, the synergistic ratio is the largest, and the synergistic effect is the most obvious.

It has been found through tests that the combination of cyclazone and active ingredient B is effective against gray mold, sclerotinia, brown spot, scab, downy mildew, leaf mold, powdery mildew, anthracnose, rice blast, The prevention and control of sheath blight, canker, blight, black shank, rust, leaf blight, spotted leaf spot, ring spot, scab, and leaf spot all have obvious synergistic effects, and the synergistic ratios are all above 1.50 .

Drug efficacy test part

The experimental chemicals were all developed and provided by Shaanxi Meibang Pesticide Co., Ltd. Control drug: 50% cyclohexasulfame wettable powder (self-prepared), 22.7% dicyananthraquinone suspension concentrate (commercially available), 40% triethylphosphonate aluminum wettable powder (commercially available), 24% activated ester Suspending agent (self-made), 40% chlorothalonil suspending agent (commercially available), 50% captan wettable powder (commercially available).

Application Example Heptacycline and active ingredient B and its compound efficacy test for controlling tomato gray mold

The experiment was arranged in the suburbs of Xi'an City, Shaanxi Province, and the condition of Botrytis cinerea was investigated before the drug application. The pesticide was applied for the first time at the early stage of the disease, and the pesticide was applied every 7 days, and the pesticide was applied twice in total. 7 days, 15 days, and 20 days after the last spraying, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 15 Efficacy test of cyclohexasulfame and active ingredient B and its compound control and control of Botrytis cinerea

It can be seen from Table 15 that the combination of cyclazone and active ingredient B can effectively control tomato gray mold, and the control effect is better than that of a single agent, and the control effect period is long. And it can control tomato anthracnose and blight, and the control effect is over 96%. There is no adverse effect on the target crops within the scope of the test drug.

APPLICATION EXAMPLES Octacycline and Active Component B and Their Compound Control Efficacy Test on Apple Ring Blight

The experiment was arranged in Xianyang City, Shaanxi Province, and the condition of apple ring spot was investigated before the drug application. The drug was applied for the first time at the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 7 days, 15 days, and 30 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 16 Efficacy test of cyclohexasulfame and active ingredient B and its compound in preventing and treating apple ringworm

It can be seen from Table 16 that the combination of cyclazone and active ingredient B can effectively prevent and control apple ring spot, and the control effect is better than that of a single agent, and the control effect period is long. And it can control apple powdery mildew, brown spot, spotted leaf spot, anthracnose, scab, and the control effect is over 96%. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 9 Cyclosulfame and active ingredient B and its compound efficacy test for controlling rice blast

The experiment was arranged in Hanzhong City, Shaanxi Province, and the disease condition of rice blast was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 7 days, 15 days, and 20 days after the last spraying, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 17 Efficacy test of cyclohexasulfame and active ingredient B and its compound for controlling rice blast

It can be seen from Table 17 that the combination of cyclazone and active ingredient B can effectively control rice blast, and the control effect is better than that of a single agent, and the control effect period is long. And it can control rice sheath blight, and the control effect is over 96%. There is no adverse effect on the target crops within the scope of the test drug.

APPLICATION EXAMPLE Cyclohexasulfame and active ingredient B and its compound efficacy test for preventing and treating wheat powdery mildew

This experiment was arranged in Weinan City, Shaanxi Province, and the condition of wheat powdery mildew was investigated before the drug application. The drug was applied for the first time at the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 7 days, 15 days, and 30 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 18 Efficacy test of cyclohexasulfame and active ingredient B and its compound for controlling wheat powdery mildew

It can be seen from Table 18 that the combination of cyclazone and active ingredient B can effectively control wheat powdery mildew, and the control effect is better than that of a single agent, and the control effect period is long. And it can control wheat sheath blight, rust, leaf spot, and the control effect is over 96%. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 11 Cyclosulfame and active ingredient B and its compound efficacy test for preventing and treating pear tree scab

This experiment was arranged in Xianyang City, Shaanxi Province, and the condition of pear scab was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 19 Efficacy test of cyclohexasulfame and active ingredient B and its compound in the control of pear scab

It can be seen from Table 19 that the combination of cyclazone and active ingredient B can effectively control pear scab, and the control effect is better than that of a single agent, and the control effect period is long. And it can control pear tree powdery mildew, brown spot, ring spot, anthracnose, and the control effect is more than 96%. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Cyclohexasulfam and Active Component B and Their Compound Control Efficacy Test on Cucumber Botrytis

The experiment was arranged in the suburbs of Xi'an City, Shaanxi Province, and the condition of cucumber gray mold was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice. 7 days, 15 days, and 30 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 20 Efficacy test of cyclohexasulfame and active ingredient B and their compound for controlling gray mold of cucumber

It can be seen from Table 20 that the combination of cyclazone and active ingredient B can effectively control cucumber gray mold, and the control effect is better than that of a single agent, and the control effect period is long. And it can control cucumber powdery mildew, sclerotinia, anthracnose, and the control effect is above 96%. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Thirteen cyclohexasulfame and active ingredient B and its compound efficacy test on controlling grape downy mildew

The experiment was arranged in the suburbs of Weinan City, Shaanxi Province, and the condition of grape downy mildew was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 7 days, 15 days, and 30 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 21 Efficacy test of cyclohexasulfame and active ingredient B and their compound for controlling grape downy mildew

It can be seen from Table 21 that the combination of cyclazone and active ingredient B can effectively control grape downy mildew, and the control effect is better than that of a single agent, and the control effect period is long. And it can control grape powdery mildew, botrytis and anthracnose, and the control effect is above 96%. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Tetracycline sulfastrobin and active ingredient B and its compound efficacy test for preventing and treating capsicum anthracnose

This experiment was arranged in Qishan County, Baoji City, Shaanxi Province. The condition of pepper anthracnose was investigated before the medicine was administered. The medicine was applied for the first time at the early stage of the disease, and once every 7 days, and the medicine was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows: Table 22 Efficacy test of cyclohexasulfame and active ingredient B and their compound for preventing and treating pepper anthracnose

It can be seen from Table 22 that the combination of cyclazone and active ingredient B can effectively prevent and control capsicum anthracnose, and the control effect is better than that of a single agent, and the control effect period is long. And it can prevent and control citrus powdery mildew, scab, botrytis and blight, and the control effect is over 96%. There is no adverse effect on the target crops within the scope of the test drug.

After the tests in different places all over the country, it was concluded that the combination of cyclazone, dicyanoanthraquinone, aluminum triethylphosphonate, activated ester, chlorothalonil and captan was effective against botrytis cinerea on various crops. , Sclerotinia, Brown Spot, Scab, Downy Mildew, Leaf Mildew, Powdery Mildew, Anthracnose, Rice Blast, Sheath Blight, Canker, Blight, Blackleg, Rust, Leaf Blight, Spot The control effect of common diseases such as deciduous disease, ring disease, scab and leaf spot disease is more than 95%, which is better than that of a single agent, and the synergistic effect is obvious.

Claims (6)

1. A pesticide composition containing cyclazone, characterized in that the effective active ingredients are active ingredient A and active ingredient B, and the weight ratio of active ingredient A to active ingredient B is 1: 70 ~ 70: 1, said The active ingredient A is cyclamen, and the active ingredient B is dicyananthraquinone. 2. The pesticide composition containing cyclohexasulfame according to claim 1, wherein the weight ratio of the active ingredient A to the active ingredient B is 1:50~50:1. 3. The pesticide composition containing cyclazone according to claim 2, characterized in that the weight ratio of cyclazone to dicyananthraquinone is 1:15~30:1. 4. The pesticide composition containing cyclazone according to any one of claims 1 to 3, characterized in that: the composition is made into wettable powder, water dispersible granule, suspending agent, suspoemulsion, micron Emulsion, emulsion in water, microcapsule suspension, microcapsule suspension-suspension concentrate. 5. The application of the cyclohexasulfame-containing pesticide composition according to claim 4 for preventing and treating crop diseases. 6. The application according to claim 5, characterized in that: said diseases include gray mold, sclerotinia, brown spot, scab, downy mildew, leaf mold, powdery mildew, anthracnose, Rice blast, sheath blight, canker, blight, black shank, rust, leaf blight, leaf spot, ring spot, scab, leaf spot.