CN103610869A - Burn cream and preparation method thereof - Google Patents
Burn cream and preparation method thereof Download PDFInfo
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- CN103610869A CN103610869A CN201310638182.0A CN201310638182A CN103610869A CN 103610869 A CN103610869 A CN 103610869A CN 201310638182 A CN201310638182 A CN 201310638182A CN 103610869 A CN103610869 A CN 103610869A
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- burn
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- burn cream
- chrysanthemi indici
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Abstract
The invention discloses burn cream. The burn cream is ointment prepared from the following materials: safflower, sanguisorba officinalis, cacumen biotae, pseudo-ginseng, resina draconis and chrysanthemum indicum. The materials are washed, dried, roasted, grinded into powder and sieved, and material medicine powder is uniformly mixed and blended into cream by hedgehog oil and snake oil to obtain the burn cream. According to the burn cream and the preparation method disclosed by the invention, defects of existing burn medicines can be solved, thermal burn, chemical burn, radiation burn and physical burn can be effectively treated; a preparation process is simple, safe and reliable.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine that Chinese medicine prepared as raw material of take, especially a kind of ointment for the treatment of all types of burns.
Background technology
At present for the drug kinds of burn and so on seldom, and existing burn medicine poor effect, particularly can not infection control to deep burn, easily cause cicatrix.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of burn cream and preparation method thereof, can solve the shortcoming of existing burn class medicine, can effectively treat heat injury, chemical burn, radiation burn and physical property burn; Manufacturing process is simple, safe and reliable.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: a kind of burn cream, and the ointment that it is made by the raw material of following weight portion proportioning:
Flos Carthami 5～30 Radix Sanguisorbae 5～40 Cacumen Platycladi 5～35 Radix Notoginseng 10～60
Sanguis Draxonis 5～40 Flos Chrysanthemi Indici 5～15 Rrinaceus earopaeus oil 20～90 Adeps Serpentiss 15～75.
Preferably, the ointment that it is made by the raw material of following weight portion proportioning:
Flos Carthami 10～25 Radix Sanguisorbae 15～30 Cacumen Platycladi 8～15 Radix Notoginseng 25～35
Sanguis Draxonis 10～22 Flos Chrysanthemi Indici 10～25 Rrinaceus earopaeus oil 40～80 Adeps Serpentiss 35～62.
The optimization weight portion proportioning of each raw material is:
Flos Carthami 10 Radix Sanguisorbae 20 Cacumen Platycladi 10 Radix Notoginseng 30
Sanguis Draxonis 15 Flos Chrysanthemi Indici 15 Rrinaceus earopaeus oil 60 Adeps Serpentiss 40.
The preparation method of above-mentioned burn cream, the method is:
Above-mentioned each crude drug is cleaned, dried, bake, be ground into end, after sieving, by reconciling into paste with Rrinaceus earopaeus oil and Adeps Serpentis after each crude drug powder mix homogeneously, make burn cream of the present invention.
The pharmacology of each crude drug of the present invention is as follows:
Flos Carthami: Xin Wen, contains carthamone, saffloside, neocarthamin, flavochrome Flos Carthami flavochrome etc., protects and improves burned part blood circulation, can anticoagulant, and fortifying fibre protein viscosity.Saffloside can significantly improve hypoxia-bearing capability.Carthamus yellow has analgesic activity and anticonvulsant action to central nervous system.Safflower extract and water extract have antiinflammatory action.
Radix Sanguisorbae: contain Radix Sanguisorbae glycosides, I II, A B E etc. and phenolic acid compound, contain a small amount of vitamin A, hemostasis Main Ingredients and Appearance is tannin, the effect with cooling blood for hemostasis, removing toxic substances and promoting granulation, can obviously stop tissue fluid to be oozed out, shorten clotting time, empyrosis and wound healing are had to obvious effect, can reduce the permeability of blood capillary, minimizing is oozed out, is alleviated tissue edema, prevention infection, is conducive to prevent early stage shock.
Cacumen Platycladi: containing volatile oil, in oil, Main Ingredients and Appearance is a-absinthol, thujene, fenchone etc., has the effect of removing heat from blood, hemostasis, granulation promoting, blood stasis dispelling, can obviously shorten the time of oozing out and clotting time, its hemostasis active ingredient is Quercetin etc.Experiment in vitro shows, Cacumen Platycladi all has inhibitory action to staphylococcus aureus, micrococcus catarrhalis, dysentery bacterium etc.
Radix Notoginseng: mainly containing saponin, aminoacid.Radix Notoginseng propylhomoserin is the main active ingredient of hemostasis, aminoacid is the Main Ingredients and Appearance that granulation promoting is invigorated blood circulation, there is removing stasis to stop bleeding, the effect of the analgesic therapy of invigorating blood circulation, detumescence and promoting granulation, can shorten hemorrhage and clotting time, there is antiplatelet aggregation and thrombolytic effect, can promote the propagation of each function hematopoietic stem cell, there is hemoposieis, can improve humoral immune function, have analgesia, antiinflammatory action, be the primary raw material of infection control.
Sanguis Draxonis: containing compositions such as dracorhodin, dracorubin, demethyl dracorhodin, demethyl dracorubin and flavonol, chalcone derivative, resinic acid, there is the effect of the analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, parasite killing granulation promoting, can obviously reduce erythrocyte overstocks, shorten plasma recalcification time, anticoagulant, prevents thrombosis.Powder external application can suppress staphylococcus aureus and Staphylococcus albus, has certain antiinflammatory action.
Flos Chrysanthemi Indici: containing acacetin-7-rhamnose glucoside, Flos Chrysanthemi Indici lactone, bitter principle, volatile oil, vitamin A and vitamin B etc., the effect with heat-clearing and toxic substances removing, there is resisting pathogenic microbes effect, staphylococcus aureus, herpesvirus and leptospira are all had to inhibitory action, and have significant antiinflammatory action.
Rrinaceus earopaeus oil: Rrinaceus earopaeus is fatty, is rich in unsaturated fatty acid, linoleic acid, linolenic acid etc., has the effect of hemostasis, parasite killing, and its fatty acid, linoleic acid can promote skin growth is also the important source material that suppresses cicatrix simultaneously.
Adeps Serpentis: contain multiple fatty acid, linolenic acid, linoleic acid etc., granulation promoting is had infiltration, moistens, repairs effect, to empyrosis granulation promoting, invigorate blood circulation, anti-scar plays a leading role.
A kind of burn cream provided by the invention and preparation method thereof, beneficial effect is as follows:
1, the growth of whole formula anti-inflammation, blood activating and promoting tissue regeneration, inhibition cicatrix.Can treatment all kinds of heat injury (raging fire, boiled water etc.), chemical burn (as sulphuric acid, hydrochloric acid etc.), physics burn (medicine burn etc.), be suitable for the crowd's of all ages and classes, different sexes, different work posts dissimilar burn patient in various degree.
2, to select natural material be raw material to formula of the present invention, and each component meets pharmaceutical control law regulation and utilizes the comprehensive function of each taste Chinese medicine to treat various burns, can a side multiplex and little to human body toxic and side effects, easily absorbs, and can not recur, and curative effect is good.
3, this formula is outer spreads on after patient burn wound, and pain relieving immediately, has positive effect after twenty four hours: start detumescence and promoting granulation, the average rehabilitation duration of dark two degree is about 18 days, and being greatly shorter than existing burn cream needs the rehabilitation duration of at least 35 days.Can be at short notice absolute infection control, and granulation promoting is fast, deep burn can be exempted from skin-grafting.This formula also can be used for the treatment of decubital ulcer and other wound, and effect is fine.
By to applying the tracing study of the 347 routine all kinds burn patients of this medicine, recovery effects is good, and effective percentage reaches 99.1%.
For showing the therapeutic effect of medicine of the present invention to all kinds burns, the present invention uses all kinds burn patients of these medicines to carry out clinical follow-up observation to 347 examples, makes the observation period by oneself to take 7 days as a course for the treatment of.
Using method: by the burn cream bottling sealing making, take at every turn and be applied on a small quantity patient burn wound, once-a-day, with the wrapping of aseptic cotton gauze.Clinical follow-up observation result is as shown in table 1.
table 1 is used the curative effect (n, %) of medicine of the present invention
The therapeutic effect of medicine of the present invention can also show from the therapeutic process of following model case:
Model case 1: Yan, man, 48 years old, because ethanol plays fire burn, the burn gross area 55%, wherein third degree burn 17%, second degree burn 38%, is used after the present invention pain relieving immediately for the first time, after using twenty four hours, start detumescence and promoting granulation, use the present invention to treat 20 days, wound surface major part is almost recovered, and uses the present invention to treat 30 days, wound surface is all fully recovered, and does not need skin-grafting.
Model case 2: field, female, 16 years old, because thermos flask blast is by burn facial area, second degree burn 3%, was used the present invention to treat recovery from illness in 5 days.
Model case 3: end certain, female, 22 years old, by sulfuric acid burn face, cervical region, chest and both hands, use the present invention to treat after 10 days, start to take a turn for the better, treat wound surface recovery from illness after 26 days, without any cicatrix.
Model case 4: Zheng, man, 46 years old, steam Fructus Lycopersici esculenti, bottle cover ejection, burn right eye, is diagnosed as Corneal burn, uses the present invention to treat recovery from illness in 15 hours.
The specific embodiment
Embodiment 1
Get Flos Carthami 5g, Radix Sanguisorbae 5g, Cacumen Platycladi 5g, Radix Notoginseng 10g, Sanguis Draxonis 5g, Flos Chrysanthemi Indici 5g,
By the Flos Carthami of above-mentioned weight, Radix Sanguisorbae, Cacumen Platycladi, Radix Notoginseng, Sanguis Draxonis, Flos Chrysanthemi Indici, cleans, and dries, and bakes, and is ground into end, after sieving, by reconciling into paste with 20g Rrinaceus earopaeus oil and 15g Adeps Serpentis after each crude drug powder mix homogeneously, makes burn cream of the present invention.
Embodiment 2
Get Flos Carthami 30g, Radix Sanguisorbae 40g, Cacumen Platycladi 35g, Radix Notoginseng 60g, Sanguis Draxonis 4g, Flos Chrysanthemi Indici 15g,
By the Flos Carthami of above-mentioned weight, Radix Sanguisorbae, Cacumen Platycladi, Radix Notoginseng, Sanguis Draxonis, Flos Chrysanthemi Indici, cleans, and dries, and bakes, and is ground into end, after sieving, by reconciling into paste with 90g Rrinaceus earopaeus oil and 75g Adeps Serpentis after each crude drug powder mix homogeneously, makes burn cream of the present invention.
Embodiment 3
Get Flos Carthami 10g, Radix Sanguisorbae 15g, Cacumen Platycladi 8g, Radix Notoginseng 25g, Sanguis Draxonis 10g, Flos Chrysanthemi Indici 10g,
By the Flos Carthami of above-mentioned weight, Radix Sanguisorbae, Cacumen Platycladi, Radix Notoginseng, Sanguis Draxonis, Flos Chrysanthemi Indici, cleans, and dries, and bakes, and is ground into end, after sieving, by reconciling into paste with 40g Rrinaceus earopaeus oil and 35g Adeps Serpentis after each crude drug powder mix homogeneously, makes burn cream of the present invention.
Embodiment 4
Get Flos Carthami 25g, Radix Sanguisorbae 30g, Cacumen Platycladi 15g, Radix Notoginseng 35g, Sanguis Draxonis 22g, Flos Chrysanthemi Indici 25g,
By the Flos Carthami of above-mentioned weight, Radix Sanguisorbae, Cacumen Platycladi, Radix Notoginseng, Sanguis Draxonis, Flos Chrysanthemi Indici, cleans, and dries, and bakes, and is ground into end, after sieving, by reconciling into paste with 80g Rrinaceus earopaeus oil and 62g Adeps Serpentis after each crude drug powder mix homogeneously, makes burn cream of the present invention.
Embodiment 5
Get Flos Carthami 10g, Radix Sanguisorbae 20g, Cacumen Platycladi 10g, Radix Notoginseng 30g, Sanguis Draxonis 15g, Flos Chrysanthemi Indici 15g,
By the Flos Carthami of above-mentioned weight, Radix Sanguisorbae, Cacumen Platycladi, Radix Notoginseng, Sanguis Draxonis, Flos Chrysanthemi Indici, cleans, and dries, and bakes, and is ground into end, after sieving, by reconciling into paste with 60g Rrinaceus earopaeus oil and 40g Adeps Serpentis after each crude drug powder mix homogeneously, makes burn cream of the present invention.
Claims (4)
1. a burn cream, is characterized in that the ointment that it is made by the raw material of following weight portion proportioning:
Flos Carthami 5～30 Radix Sanguisorbae 5～40 Cacumen Platycladi 5～35 Radix Notoginseng 10～60
Sanguis Draxonis 5～40 Flos Chrysanthemi Indici 5～15 Rrinaceus earopaeus oil 20～90 Adeps Serpentiss 15～75.
2. a kind of burn cream according to claim 1, is characterized in that the ointment that it is made by the raw material of following weight portion proportioning:
Flos Carthami 10～25 Radix Sanguisorbae 15～30 Cacumen Platycladi 8～15 Radix Notoginseng 25～35
Sanguis Draxonis 10～22 Flos Chrysanthemi Indici 10～25 Rrinaceus earopaeus oil 40～80 Adeps Serpentiss 35～62.
3. a kind of burn cream according to claim 1, is characterized in that the weight portion proportioning of each raw material is:
Flos Carthami 10 Radix Sanguisorbae 20 Cacumen Platycladi 10 Radix Notoginseng 30
Sanguis Draxonis 15 Flos Chrysanthemi Indici 15 Rrinaceus earopaeus oil 60 Adeps Serpentiss 40.
4. a preparation method for burn cream described in above-mentioned each claim, is characterized in that the method is:
Above-mentioned each crude drug is cleaned, dried, bake, be ground into end, after sieving, by reconciling into paste with Rrinaceus earopaeus oil and Adeps Serpentis after each crude drug powder mix homogeneously, make burn cream of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310638182.0A CN103610869A (en) | 2013-12-03 | 2013-12-03 | Burn cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310638182.0A CN103610869A (en) | 2013-12-03 | 2013-12-03 | Burn cream and preparation method thereof |
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| Publication Number | Publication Date |
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| CN103610869A true CN103610869A (en) | 2014-03-05 |
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| CN201310638182.0A Pending CN103610869A (en) | 2013-12-03 | 2013-12-03 | Burn cream and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031617A (en) * | 2015-06-30 | 2015-11-11 | 桂林华诺威基因药业有限公司 | Burn healing paste |
| CN116115814A (en) * | 2023-03-10 | 2023-05-16 | 潍坊医学院附属医院 | Trauma hemostatic dressing based on chitin |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101007139A (en) * | 2007-01-24 | 2007-08-01 | 郑爱召 | An external applied medicine for treating burn and scald |
| CN101274047A (en) * | 2007-03-26 | 2008-10-01 | 孙桂庭 | External-use ointment for treating burn and method of preparing the same |
-
2013
- 2013-12-03 CN CN201310638182.0A patent/CN103610869A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101007139A (en) * | 2007-01-24 | 2007-08-01 | 郑爱召 | An external applied medicine for treating burn and scald |
| CN101274047A (en) * | 2007-03-26 | 2008-10-01 | 孙桂庭 | External-use ointment for treating burn and method of preparing the same |
Non-Patent Citations (2)
| Title |
|---|
| 李彦秋等: "中药外用治疗烧烫伤进展", 《人民军医》, vol. 55, no. 9, 1 September 2012 (2012-09-01), pages 889 - 910 * |
| 袁汀等: "外用中药治疗烧烫伤的研究进展", 《光明中医》, vol. 25, no. 11, 30 November 2010 (2010-11-30), pages 2151 - 2153 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031617A (en) * | 2015-06-30 | 2015-11-11 | 桂林华诺威基因药业有限公司 | Burn healing paste |
| CN116115814A (en) * | 2023-03-10 | 2023-05-16 | 潍坊医学院附属医院 | Trauma hemostatic dressing based on chitin |
| CN116115814B (en) * | 2023-03-10 | 2024-11-08 | 潍坊医学院附属医院 | Chitin-based wound hemostatic dressing |
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Application publication date: 20140305 |