CN105560581A - Traditional Chinese medicine tincture for treating chilblain and preparation method thereof - Google Patents
Traditional Chinese medicine tincture for treating chilblain and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine tincture for treating chilblain and a preparation method thereof. The traditional Chinese medicine tincture is prepared from the following raw materials in parts by weight: 8 to 13 parts of mulberry twig, 6 to 12 parts of galium verum, 9 to 13 parts of Korean raspberry root, 5 to 10 parts of root and bark of lokao buckthorn, 3 to 12 parts of alligator weed, 4 to 9 parts of begonia fimbristipula, 6 to 11 parts of walnut oil, 4 to 10 parts of euonymus bungeanus, 7 to 11 parts of ammopiptanthus mongolicus, 9 to 12 parts of herpetospermum pedunculosum, 6 to 13 parts of solanum surattense, 4 to 11 parts of circaea lutetiana, 3 to 9 parts of strophanthus divaricatus, 5 to 8 parts of herb of nightshadeleaf ironweed, and 7 to 10 parts of longstamen loosestrife herb. The tincture is safe, does not have any side effect, can shorten the cure time, has the functions of dispelling wind, reliving itch, removing toxin, eliminating swelling, warming and tonifying kidney yang, activating blood, freeing collaterals, relaxing muscle, dissipating stasis, removing sore-toxin, promoting wound healing, promoting tissue regeneration, and relieving pains, can promote the blood circulation in the chilblain parts, regulate internal secretion, and promote the tissue regeneration of skin tissue, and finally cures chilblain. Moreover, after the treatment, the relapse is difficult, and no pigment or scar is left.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Traditional Chinese medicine tincture and the method for making thereof of curing chilblain.
Background technology
Chilblain is common in winter, and due to local skin erythema, the tumidus infringement repeatedly that very cold causes, vesicle, ulcer can appear in severe patient, and the course of disease is slow, and weather turns warm rear spontaneous recovery, easily recurs.Cold is the main cause of chilblain morbidity.Its pathogenic factor be the skin of chilblain patient when running into cold (0 ~ 10 DEG C), the moist or changes in temperature sudden turn of events, local small artery shrinks, arteries paralysis of a specified duration and expanding, venous congestion, and local blood circulation is bad and fall ill.In addition, the factor such as humidity of skin, tip blood capillary deformity, autonomic nerve dysfunction, malnutrition, dyshormonia of patient self also may participate in morbidity.Lack the generation that the factors such as motion, acrohyperhidrosis humidity, footgear tension and long-term outdoor low operating temperatures all can cause chilblain.Chilblain is apt to occur in early winter, early spring, and with child, women and peripheral blood circulation, bad person is common, the performances such as these patients often send out cool with acral body skin, acrocyanosis, hyperhidrosis.Skin lesion is apt to occur in the places such as finger, the back of the hand, face, auricle, toes, sufficient edge, heel, the distribution of normal both sides.Common infringement is the edematous erythema of the congestive dark violet redness protuberance of limitation, and indefinite border, edge is cerise, and surface is nervous glossy, and matter is soft.Local pressing can be faded, and goes to press rear redness to recover gradually.Can there is vesicle in severe patient, break and form rotten to the corn or ulcer, retain pigmentation or atrophic scar more afterwards.Gargalesthesia is obvious, aggravates after heated, pain after festering.A kind of chilblain of specific type is had to be more common in the thigh of women.There is characteristic to be the infiltrating speckle of bluish red color clinically, be symmetrically distributed in the facies lateralis femoris of obesity, occasionally can have Secondary cases ulcer and often merge horny follicular plug.These infringements are completely relevant with cold expoure, and disappear in warm environment.
Treatment: 1. systematic treating.The vasodilations such as oral nicotiamide, nifedipine.Or Radix Salviae Miltiorrhizae (20ml) is added quiet of low molecular dextran 500ml, there is blood vessel dilating, improve microcirculation, increase the effect such as blood flow and thrombus dissolving.2. topical therapeutic.Available helium-neon laser and infrared ray radiation, or after making laser point irradiation (tsu san li, fuliu etc.), chilblain partial row is defocused and generally irradiates.Non-ulceration person can externally used compound heparin ointment, hirudiod, vitamin E ointment etc.Attached immersion bubble affected part of boiling medicine, available osmanthus, every day 3 times, each 20 ~ 30 minutes, affected part rubbed by leaching limit, limit medicinal residues.(square medicine consists of: Ramulus Cinnamomi, Flos Carthami, Radix Aconiti Lateralis Preparata, Folium Perillae, each 20g of Herba Schizonepetae, and add water 3000ml, is fried boiling, slightly cold rear use.Ulceration person external 5% boric acid ointment, 1% erythromycin ointment etc.).
Application publication number CN103393951A(application number 201310352909.9) Chinese patent literature disclose a kind of chilblain tincture, it forms with alcohol-pickled with Cortex Dictamni, Radix Et Rhizoma Rhei, the Pseudobulbus Bletillae (Rhizoma Bletillae), Ramulus Cinnamomi, Flos Carthami, Radix Angelicae Sinensis and Radix Angelicae Dahuricae kinds of traditional Chinese medicines, wherein 75% ethanol of 1000ml is joined the dosage of each taste Chinese medicine and is: Cortex Dictamni 30-50g, Radix Et Rhizoma Rhei 20-30g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30-40g, Ramulus Cinnamomi 20-30g, Flos Carthami 20-30g, Radix Angelicae Sinensis 30-40g, Radix Angelicae Dahuricae 10-20g.Application publication number CN103463441A(application number 201310387396.5) Chinese patent literature disclose a kind of Chinese medicinal ointment for the treatment of chilblain, wherein, comprise the following active component according to unit of weight preparation: Radix Aconiti 30-40g, Rhizoma Polygoni Cuspidati 20-30g, Exocarpium Citri Rubrum 20-30g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30g, Radix Aconiti Kusnezoffii 10-20g, Semen Vaccariae 10-20g, Herba Asari 10-20g, Alumen 10-20g, Fructus Toosendan 10-20g, Natrii Sulfas 5-10g, Lignum Dalbergiae Odoriferae 10-20g, Herba Cirsii 10-20g, Radix Puerariae 10-20g, Fructus Piperis 10-20g.Application publication number CN104998046A(application number 201510353915.5) Chinese patent literature disclose a kind of Chinese medicine ointment for the treatment of chilblain, the weight portion of its constitutive material is: Radix Notoginseng 5-8, Squama Manis 2-4, Caulis Spatholobi 4-5, Concha Arcae 1-2, Lithargyrum 4-5, Herba Sarcandrae 2-4, Semen Hoveniae (Fructus Hoveniae)
Sub-6-8, Pericarpium Citri Reticulatae 2-4, Radix Scrophulariae 1-2, Folium Mori 6-8, Radix Angelicae Dahuricae 3-5, Radix Et Rhizoma Rhei 2-4, mentha leave 8-10, Rhizoma Chuanxiong 4-5, Flos Lilii viriduli 2-4, Radix Crataegi 1-3, Caulis et Folium Kochiae 2-4, Radix Angelicae Pubescentis 3-5, Radix Rubiae 2-4 and Radix Angelicae Sinensis 5-6.
At present, the medicine for the treatment of chilblain is a lot, and majority is temporary relief of symptoms, controls table and is but difficult to dig up the roots, and the cycle of curing is long, and the coming year is easy recurrent exerbation again.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Traditional Chinese medicine tincture and the method for making thereof of curing chilblain.The present invention safely, have no side effect, healing time can be shortened, there is effect of dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, warming and recuperating the kidney-YANG, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons dissipating blood stasis, solution sore, expelling pus and promoting granulation, eliminating stasis to stop pain, can the blood circulation at unimpeded chilblain position, endocrine regulation, promotes skin tissue cell regeneration, finally reach curative effect, and not easily recur after curing, do not stay pigment, do not stay cicatrix.
Technical scheme of the present invention is:
Cure the Traditional Chinese medicine tincture of chilblain, take off the primary raw material medicine stating weight proportion and be prepared from: Ramulus Mori 8-13, Herba galii veri 6-12, Radix rubi coreani 9-13, Cortex Rhamni Globosae Radicis 5-10, Radix Alternantherae philoxeroidis 3-12, Rhizoma Begoniae Fimbristipulatae 4-9, Oleum Juglandis 6-11, Herba Euonymi Bungeani 4-10, Caulis et Folium Ammopiptanthi Mongolici 7-11, Fructus Herpetospermi pedunculosi 9-12, soda-apple nightshade herb 6-13, globule grass 4-11, Radix Strophanthi Divaricati 3-9, Herba vernoniae solanifoliae 5-8, Herba Lysimachiae Lobelioidis 7-10.
Cure the Traditional Chinese medicine tincture of chilblain, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Ramulus Mori 9-12, Herba galii veri 7-10, Radix rubi coreani 10-12, Cortex Rhamni Globosae Radicis 7-9, Radix Alternantherae philoxeroidis 5-9, Rhizoma Begoniae Fimbristipulatae 5-8, Oleum Juglandis 7-10, Herba Euonymi Bungeani 5-9, Caulis et Folium Ammopiptanthi Mongolici 8-10, Fructus Herpetospermi pedunculosi 10-11, soda-apple nightshade herb 8-12, the globule grass 6-10, Radix Strophanthi Divaricati 4-6, Herba vernoniae solanifoliae 6-7, Herba Lysimachiae Lobelioidis 8-9.
Cure the Traditional Chinese medicine tincture of chilblain, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Ramulus Mori 10, Herba galii veri 9, Radix rubi coreani 11, Cortex Rhamni Globosae Radicis 8, Radix Alternantherae philoxeroidis 7, Rhizoma Begoniae Fimbristipulatae 6, Oleum Juglandis 9, Herba Euonymi Bungeani 8, Caulis et Folium Ammopiptanthi Mongolici 9, Fructus Herpetospermi pedunculosi 10.5, soda-apple nightshade herb 10, globule grass 8, Radix Strophanthi Divaricati 5, Herba vernoniae solanifoliae 6.5, Herba Lysimachiae Lobelioidis 8.5.
The Traditional Chinese medicine tincture of above-mentioned treatment chilblain preparation method be:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, adds 9-12 times amount rice water, and soak 2-4 hour, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, crosses 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dry 9-13 hour, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 10-16 minute, the amount of boiling water is 13-18 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 8-12 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 5-10 days, remove slag, to obtain final product.
Preferably be, in step (1), to add 10-11 times amount rice water.
Preferably be in step (1), soak 2.5-3.5 hour.
Preferably be in step (2), dry 10-12 hour.
Preferably be, in step (3), to put in boiling water and boil 12-15 minute.
Preferably be in step (3), the amount of boiling water is 15-17 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight.
Preferably be in step (4), the amount of ethanol is 9-11 times of step (1), step (2) and step (3) gained coarse powder gross weight.
Preferably be in step (4), sealing dipping 6-9 days.
Be more preferably, in step (1), add 10.5 times amount rice waters.
Be more preferably, soak 3 hours in step (1).
Be more preferably, drying 11 hours in step (2).
Be more preferably, in step (3) mid-boiling water, boil 14 minutes.
Be more preferably, in step (3), the amount of boiling water is 16 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight.
Be more preferably, in step (4), the amount of boiling water is 16 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight.
Be more preferably, sealing dipping 8 days in step (4).
The Traditional Chinese medicine tincture scientific formula for the treatment of chilblain provided by the invention, preparation method is simple.In addition, excellent results of the present invention also shows:
1, there is effect of dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, warming and recuperating the kidney-YANG, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons dissipating blood stasis, solution sore, expelling pus and promoting granulation, eliminating stasis to stop pain, can the blood circulation at unimpeded chilblain position, endocrine regulation, promotes skin tissue cell regeneration, finally reaches curative effect;
, have no side effect 2, safely;
3, healing time can be shortened;
4, treating both the principal and secondary aspects of a disease, not easily recurs after healing, does not stay pigment, does not stay cicatrix.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
Embodiment 1 cures the Traditional Chinese medicine tincture of chilblain, and the primary raw material medicine getting following weight parts is prepared from (every part is 220g): Ramulus Mori 8 parts, Herba galii veri 6 parts, Radix rubi coreani 9 parts, Cortex Rhamni Globosae Radicis 5 parts, Radix Alternantherae philoxeroidis 3 parts, Rhizoma Begoniae Fimbristipulatae 4 parts, Oleum Juglandis 6 parts, Herba Euonymi Bungeani 4 parts, Caulis et Folium Ammopiptanthi Mongolici 7 parts, Fructus Herpetospermi pedunculosi 9 parts, soda-apple nightshade herb 6 parts, globule grass 4 parts, Radix Strophanthi Divaricati 3 parts, Herba vernoniae solanifoliae 5 parts, Herba Lysimachiae Lobelioidis 7 parts.
The preparation method of the Traditional Chinese medicine tincture of above-mentioned treatment chilblain is:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, add 9 times amount rice waters, soak 2 hours, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, cross 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dryings 9 hours, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 10 minutes, the amount of boiling water is 13 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 8 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 5 days, remove slag, to obtain final product.
The using method that gained of the present invention cures the Traditional Chinese medicine tincture of chilblain is: external, for the cold injury position of non-diabrosis, is coated in affected part by gained Traditional Chinese medicine tincture of the present invention, repeatedly rubs with the hands to local pyrexia back and forth up and down with the centre of the palm, 3-4 time on the one; For the cold injury position of having festered, gained Traditional Chinese medicine tincture wiping rotten position of the present invention is dipped in disinfecting cotton swab, dip in outside gained Traditional Chinese medicine tincture of the present invention with aseptic dry yarn block again and be applied to rotten position, within 1 day, change dressings 1 time, after ulcer healing, again this chilblain tincture is coated onto local, repeatedly rubs with the hands to local skin with the centre of the palm and generate heat.
Embodiment 2 cures the Traditional Chinese medicine tincture of chilblain, and the primary raw material medicine getting following weight parts is prepared from (every part is 220g): Ramulus Mori 13 parts, Herba galii veri 12 parts, Radix rubi coreani 13 parts, Cortex Rhamni Globosae Radicis 10 parts, Radix Alternantherae philoxeroidis 12 parts, Rhizoma Begoniae Fimbristipulatae 9 parts, Oleum Juglandis 11 parts, Herba Euonymi Bungeani 10 parts, Caulis et Folium Ammopiptanthi Mongolici 11 parts, Fructus Herpetospermi pedunculosi 12 parts, soda-apple nightshade herb 13 parts, globule grass 11 parts, Radix Strophanthi Divaricati 9 parts, Herba vernoniae solanifoliae 8 parts, Herba Lysimachiae Lobelioidis 10 parts.
The preparation method of the Traditional Chinese medicine tincture of above-mentioned treatment chilblain is:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, add 12 times amount rice waters, soak 4 hours, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, cross 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dryings 13 hours, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 16 minutes, the amount of boiling water is 18 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 12 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 10 days, remove slag, to obtain final product.
Model case one: old XX, female, 43 years old.Before more than 10 years, patient's both hands, biped cold injury, cause chilblain, after this once to the outbreak of cold sky, even also have vesicle summer.Once attempted the treatment of multiple method, and all failed thoroughly to cure.By the agency of, carrys out here diagnosis and treatment.Patient's both hands, biped are red and swollen, many places ulcer, with pruritus, and causalgia.Use the present embodiment gained to cure the Traditional Chinese medicine tincture of chilblain after 3 days, the symptom such as pruritus, causalgia obviously alleviates, and ulcer disappears, and casts off a skin.Continuous use is after 1 week, and all diseases disappear, and lump dissipates, wound healing, cures.Follow up a case by regular visits to and do not recur so far, do not leave mottle and cicatrix.
Embodiment 3 cures the Traditional Chinese medicine tincture of chilblain, and the primary raw material medicine getting following weight parts is prepared from (every part is 220g): Ramulus Mori 9 parts, Herba galii veri 7 parts, Radix rubi coreani 10 parts, Cortex Rhamni Globosae Radicis 7 parts, Radix Alternantherae philoxeroidis 5 parts, Rhizoma Begoniae Fimbristipulatae 5 parts, Oleum Juglandis 7 parts, Herba Euonymi Bungeani 5 parts, Caulis et Folium Ammopiptanthi Mongolici 8 parts, Fructus Herpetospermi pedunculosi 10 parts, soda-apple nightshade herb 8 parts, globule grass 6 parts, Radix Strophanthi Divaricati 4 parts, Herba vernoniae solanifoliae 6 parts, Herba Lysimachiae Lobelioidis 8 parts.
The preparation method of the Traditional Chinese medicine tincture of above-mentioned treatment chilblain is:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, add 10 times amount rice waters, soak 2.5 hours, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, cross 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dryings 10 hours, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 12 minutes, the amount of boiling water is 15 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 9 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 6 days, remove slag, to obtain final product.
Model case two: in XX, female, 24 years old.Patient has just suffered from chilblain from childhood, and all freezes every year.Once in many ways sought medical advice, and failed to cure.This brings many inconvenience to the life of patient.To get off here diagnosis and treatment in the introduction of friend.There is vesicle in patient's the back of the hand, breaking, it is rotten to the corn to be formed, and color of the leather is purple dark, insensitive.The present embodiment gained is used to cure the Traditional Chinese medicine tincture of chilblain after 4 days, successful.Continuous use is after 1 week, and all diseases disappear, and cures.Follow up a case by regular visits to and do not recur so far, do not leave mottle and cicatrix.
Embodiment 4 cures the Traditional Chinese medicine tincture of chilblain, and the primary raw material medicine getting following weight parts is prepared from (every part is 220g): Ramulus Mori 12 parts, Herba galii veri 10 parts, Radix rubi coreani 12 parts, Cortex Rhamni Globosae Radicis 9 parts, Radix Alternantherae philoxeroidis 9 parts, Rhizoma Begoniae Fimbristipulatae 8 parts, Oleum Juglandis 10 parts, Herba Euonymi Bungeani 9 parts, Caulis et Folium Ammopiptanthi Mongolici 10 parts, Fructus Herpetospermi pedunculosi 11 parts, soda-apple nightshade herb 12 parts, globule grass 10 parts, Radix Strophanthi Divaricati 6 parts, Herba vernoniae solanifoliae 7 parts, Herba Lysimachiae Lobelioidis 9 parts.
The preparation method of the Traditional Chinese medicine tincture of above-mentioned treatment chilblain is:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, add 11 times amount rice waters, soak 3.5 hours, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, cross 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dryings 12 hours, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 15 minutes, the amount of boiling water is 17 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 11 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 9 days, remove slag, to obtain final product.
Model case three: woods XX, man, 30 years old.Patient's readme from primary school time, just every older chilblain.Once a lot of folk prescription was used, and to examination in hospital treatment, but still recurrence after treatment.This adds many worries to patient, fears the arrival of cold winter.Unintentionally, patient hears that the present invention treats chilblain effect pretty good, diagnosis and treatment of coming.Patient points palm aubergine congestive erythema, and temperature is too low, contacts hot defensive position pruritus, pain is obvious, light red tongue, white and thin fur, deep-thready pulse.Use the present embodiment gained to cure the Traditional Chinese medicine tincture of chilblain after 3 days, symptom obviously alleviates.Continuous use is after 1 week, and all diseases disappear, and cures.Follow up a case by regular visits to and do not recur so far, do not leave mottle and cicatrix.
Embodiment 5 cures the Traditional Chinese medicine tincture of chilblain, and the primary raw material medicine getting following weight parts is prepared from (every part is 220g): Ramulus Mori 10 parts, Herba galii veri 9 parts, Radix rubi coreani 11 parts, Cortex Rhamni Globosae Radicis 8 parts, Radix Alternantherae philoxeroidis 7 parts, Rhizoma Begoniae Fimbristipulatae 6 parts, Oleum Juglandis 9 parts, Herba Euonymi Bungeani 8 parts, Caulis et Folium Ammopiptanthi Mongolici 9 parts, Fructus Herpetospermi pedunculosi 10.5 parts, soda-apple nightshade herb 10 parts, globule grass 8 parts, Radix Strophanthi Divaricati 5 parts, Herba vernoniae solanifoliae 6.5 parts, Herba Lysimachiae Lobelioidis 8.5 parts.
The preparation method of the Traditional Chinese medicine tincture of above-mentioned treatment chilblain is:
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, add 10.5 times amount rice waters, soak 3 hours, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, cross 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dryings 11 hours, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 14 minutes, the amount of boiling water is 16 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is 16 times of step (1), step (2) and step (3) gained coarse powder gross weight, sealing dipping 8 days, remove slag, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Ramulus Mori: base is former: be the dry twig of moraceae plants Mulberry.The property of medicine: micro-hardship, flat.Return Liver Channel.Function cures mainly: wind-damp dispelling, sharp joint.For takeing on arm, joint aches is numb.
Herba galii veri: base is former: be the herb of Maguireothamnus speciosus Herba galii veri.The property of medicine: micro-pungent; Bitter; Be slightly cold.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation to restore menstrual flow; Dispelling wind for relieving itching.Main hepatitis; Ascites; Laryngopharynx swelling and pain; Furuncle toxic swelling; Traumatic injury; Women's amenorrhea; Leukorrhagia; Venom; Honor measles; Paddy field dermatitis.
Radix rubi coreani: base is former: be the root of rosaceous plant rubus coreanus.The property of medicine: bitter, puckery, flat, nontoxic.Return liver, kidney channel.Function cures mainly: promoting blood circulation and hemostasis, expelling wind and removing dampness.Main traumatic injury, fracture, menoxenia, spits blood, epistaxis, rheumatic arthralgia, edema, dysuria, scrofula.
Cortex Rhamni Globosae Radicis: base is former: be stem, leaf, the root bark of Rhamnaceae plant Rhamnus globosus.The property of medicine: bitter in the mouth; Puckery; Cold.Return lung; Spleen; Stomach; Large intestine channel.Function cures mainly: parasite killing helps digestion; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm.Main proglottid of tapeworm; Food stagnation; Scrofula; Asthma.
Radix Alternantherae philoxeroidis: base is former: be the herb of amaranthaceous plant Alternanthera philoxeroides.The property of medicine: bitter; Sweet; Cold in nature.Return lung; The heart; Liver; Urinary bladder channel.Function cures mainly: clearing away heat and cooling blood; Removing toxic substances; Diuresis.Main hemoptysis; Hematuria; Cold, fever; Measles; Encephalitis B; Jaundice; Stranguria with turbid discharge; Mumps; Eczema; Carbuncle furuncle; Venom.
Rhizoma Begoniae Fimbristipulatae: base is former: be bulb or the Herb of Begoniaceae plant Radix Semiaquilegiae.The property of medicine: sweet in the mouth, cool in nature.Function cures mainly: clearing away heat and cooling blood; Relieving cough and resolving phlegm; Removing toxic substances and promoting subsidence of swelling.Main exogenous high fever; Heatstroke; Cough due to lung-heat; Laryngopharynx swelling and pain; Furuncle; Scrofula; Scabies; Burn and scald; Traumatic injury stasis of blood pain.
Oleum Juglandis: base is former: be the fatty oil of juglandaceae plant Semen Juglandis kernel.The property of medicine: pungent; Sweet; Warm in nature.Function cures mainly: warming and recuperating the kidney-YANG; Intestine moistening; Anthelmintic; Antipruritic; Sore.The main soreness of waist of suffering from a deficiency of the kidney; Dryness of the intestine constipation; Abdominal pain due to worm stagnation; Ting ear comes to a head; Scabies; Chilblain; Bromhidrosis.
Herba Euonymi Bungeani: base is former: be root, the bark of Celastraceae vegetable silk Populus deltoides.The property of medicine: bitter, pungent, cool.Return liver,spleen,kidney warp.Function cures mainly: expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Main air wet arthritis, lumbago, traumatic injury wound is swollen, thromboangiitis obliterans, lung abscess, epistaxis, furuncle toxic swelling.
Caulis et Folium Ammopiptanthi Mongolici: base is former: be stem, the leaf of section's plant Caulis et Folium Ammopiptanthi Mongolici or little Caulis et Folium Ammopiptanthi Mongolici.The property of medicine: pungent; Bitter; Temperature; Poisonous.GUIXIN warp.Function cures mainly: expelling wind and removing dampness, relaxing muscles and tendons dissipating blood stasis.Main chilblain, chronic rheumatic arthralgia.
Fructus Herpetospermi pedunculosi: base is former: be the fruit of cucurbitaceous plant Fructus Herpetospermi pedunculosi.The property of medicine: bitter in the mouth; Cold in nature.Function cures mainly: removing fire from the liver; Clearing gallbladder heat.Main icteric infectious hepatitis; Cholecystitis.
Soda-apple nightshade herb: base is former: be the Herb of plant of Solanaceae cattle Fructus Solani melongenae.The property of medicine: bitter in the mouth; Pungent; Slightly warm in nature; Poisonous.Function cures mainly: antitussive and antiasthmatic; Eliminating stasis to stop pain.Main chronic bronchitis; Asthma; Stomachache; Rheumatalgia lumbago and skelalgia; Scrofula; Cold pus infections; Carbuncle sore tumefacting virus; Traumatic injury.
Globule grass: base is former: be the herb of onagraceae plant globule grass.The property of medicine: acrid in the mouth; Bitter; Property is put down.Function cures mainly: lung qi dispersing cough-relieving; Vital energy regualting and blood circulation-promoting; Diuresis is detoxified.Main exogenous cough; Abdominal distention; Dysmenorrhea; Menoxenia; Amenorrhea; Have loose bowels; Edema; Drench pain; Skin ulcer swells; Panaris; Tinea is itched; Condyloma latum.
Radix Strophanthi Divaricati: base is former: be root or the stem and leaf of apocynaceae plant Radix Strophanthi Divaricati.The property of medicine: bitter; Cold in nature; Large poison.Function cures mainly: wind-damp dispelling; The meridian dredging; Separate sore; Parasite killing.Main air pain of dampness syndrome; Poliomyelitis sequela; Traumatic injury; Carbuncle skin ulcer; Scabies.
Herba vernoniae solanifoliae: base is former: be root or stem, the leaf of feverfew Folium Solani Melongenae Herba Vernonia esculenta.The property of medicine: sweet in the mouth; Bitter; Cool in nature.Function cures mainly: nourishing the lung to arrest cough; Dispelling wind for relieving itching.Main laryngopharynx swelling and pain; Pulmonary tuberculosis is coughed; Spitting of blood; Bronchitis; Gastroenteritis; Rheumatic arthralgia; Traumatic hemorrhage; Skin pruritus.
Herba Lysimachiae Lobelioidis: base is former: be the herb of the long stamen Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) of Ofthe Primulaceae.The property of medicine: sweet; Property is put down.Return lung, the heart, Liver Channel.Function cures mainly: tonify deficiency cough-relieving, subduing swelling and detoxicating, hemostasia and promoting granulation.The main deficiency of the lung, cough, acute mastitis, knife injury is hemorrhage.
Test example 1 gained of the present invention cures the clinical practice of the Traditional Chinese medicine tincture (embodiment 5) of chilblain: in January, 2011 in December ,-2012, screen 350 routine chilblain patients in 4 hospitals, wherein male 182 example, women 168 example, age 18-63 year.Be divided into two groups at random, experimental group and matched group (often organizing 175 examples).Between two groups of patients, the aspect such as sex, age, the state of an illness and course of disease compares, and no significant difference (P > 0.05), has comparability.
Therapeutic Method: experimental group uses gained of the present invention to cure the Traditional Chinese medicine tincture of chilblain, using method is: external, for the cold injury position of non-diabrosis, gained Traditional Chinese medicine tincture of the present invention is coated in affected part, repeatedly rub with the hands to local pyrexia back and forth up and down with the centre of the palm, 3-4 time on the one; For the cold injury position of having festered, gained Traditional Chinese medicine tincture wiping rotten position of the present invention is dipped in disinfecting cotton swab, dip in outside gained Traditional Chinese medicine tincture of the present invention with aseptic dry yarn block again and be applied to rotten position, within 1 day, change dressings 1 time, after ulcer healing, again this chilblain tincture is coated onto local, repeatedly rubs with the hands to local skin with the centre of the palm and generate heat.Matched group uses chilblain spirit, chilblain disappears the Drug therapy such as tincture, kibe ointment.Two groups of patients all treat after 7 days and carry out comparitive study.
Curative effect situation criterion: " the Chinese medical disease diagnosis treatment that criterion of therapeutical effect is issued with State Administration of Traditional Chinese Medicine for 1994
Criterion is accurate " be foundation.Cure: General Symptoms disappears, lump dissipates, wound healing; Take a turn for the better: General Symptoms disappears substantially, and wound surface does not heal completely; Invalid: whole body and local symptom are without improvement.Total effectively comprising cures and takes a turn for the better, and result is as shown in table 1.
Table 1: gained of the present invention cures the Traditional Chinese medicine tincture compliance test result of chilblain
Efficacy analysis: as can be seen from Table 1, experimental group cures 158 examples, cure rate 90.29%, and take a turn for the better 14 examples, improvement rate 8%, invalid 3 examples, inefficiency 1.71%, total effective rate 98.29%; Matched group cures 61 examples, cure rate 34.86%, and take a turn for the better 84 examples, improvement rate 48%, invalid 30 examples, inefficiency 17.14%, total effective rate 82.86%.The cure rate of experimental group and total effective rate are apparently higher than matched group.Test shows, the clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
Table 2: clinical symptoms is improved situation and compared
As can be seen from Table 2, in the patient of the rear experimental group for the treatment of, erythema disappears and accounts for 94%, and edema disappears and accounts for 93%, and pain disappears and accounts for 96%, and blister erosion disappearance accounts for 91%, and pruritus disappears and accounts for 97%; In the patient of matched group, erythema disappears and accounts for 53%, and edema disappears and accounts for 60%, and pain disappears and accounts for 63%, and blister erosion disappears and accounts for 49%, and pruritus disappears and accounts for 68%.Experimental group clinical symptoms is improved situation and is obviously better than matched group.
The present invention is primary raw material medicine with Ramulus Mori, Herba galii veri, Radix rubi coreani and Cortex Rhamni Globosae Radicis etc., makes the Traditional Chinese medicine tincture curing chilblain.Ramulus Mori wind-damp dispelling in side, sharp joint.Herba galii veri heat-clearing and toxic substances removing; Promoting blood circulation to restore menstrual flow; Dispelling wind for relieving itching.Radix rubi coreani promoting blood circulation and hemostasis, expelling wind and removing dampness.Cortex Rhamni Globosae Radicis parasite killing helps digestion; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm.Radix Alternantherae philoxeroidis clearing away heat and cooling blood; Removing toxic substances; Diuresis.Rhizoma Begoniae Fimbristipulatae clearing away heat and cooling blood; Relieving cough and resolving phlegm; Removing toxic substances and promoting subsidence of swelling.Oleum Juglandis warming and recuperating the kidney-YANG; Intestine moistening; Anthelmintic; Antipruritic; Sore.Herba Euonymi Bungeani expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Caulis et Folium Ammopiptanthi Mongolici expelling wind and removing dampness, relaxing muscles and tendons dissipating blood stasis.Fructus Herpetospermi pedunculosi removing fire from the liver; Clearing gallbladder heat.Soda-apple nightshade herb antitussive and antiasthmatic; Eliminating stasis to stop pain.The cough-relieving of globule grass lung qi dispersing; Vital energy regualting and blood circulation-promoting; Diuresis is detoxified.Radix Strophanthi Divaricati wind-damp dispelling; The meridian dredging; Separate sore; Parasite killing.Herba vernoniae solanifoliae nourishing the lung to arrest cough; Dispelling wind for relieving itching.The cough-relieving of Herba Lysimachiae Lobelioidis tonify deficiency, subduing swelling and detoxicating, hemostasia and promoting granulation.All medicines share, play dispelling wind for relieving itching, removing toxic substances and promoting subsidence of swelling, warming and recuperating the kidney-YANG, promoting blood circulation to remove obstruction in the collateral, relaxing muscles and tendons dissipating blood stasis altogether, separate the effect of sore, expelling pus and promoting granulation, eliminating stasis to stop pain, can the blood circulation at unimpeded chilblain position, endocrine regulation, promote skin tissue cell regeneration, finally reach curative effect.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. cure the Traditional Chinese medicine tincture of chilblain, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Ramulus Mori 8-13, Herba galii veri 6-12, Radix rubi coreani 9-13, Cortex Rhamni Globosae Radicis 5-10, Radix Alternantherae philoxeroidis 3-12, Rhizoma Begoniae Fimbristipulatae 4-9, Oleum Juglandis 6-11, Herba Euonymi Bungeani 4-10, Caulis et Folium Ammopiptanthi Mongolici 7-11, Fructus Herpetospermi pedunculosi 9-12, soda-apple nightshade herb 6-13, the globule grass 4-11, Radix Strophanthi Divaricati 3-9, Herba vernoniae solanifoliae 5-8, Herba Lysimachiae Lobelioidis 7-10.
2. the Traditional Chinese medicine tincture curing chilblain as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Ramulus Mori 9-12, Herba galii veri 7-10, Radix rubi coreani 10-12, Cortex Rhamni Globosae Radicis 7-9, Radix Alternantherae philoxeroidis 5-9, Rhizoma Begoniae Fimbristipulatae 5-8, Oleum Juglandis 7-10, Herba Euonymi Bungeani 5-9, Caulis et Folium Ammopiptanthi Mongolici 8-10, Fructus Herpetospermi pedunculosi 10-11, soda-apple nightshade herb 8-12, the globule grass 6-10, Radix Strophanthi Divaricati 4-6, Herba vernoniae solanifoliae 6-7, Herba Lysimachiae Lobelioidis 8-9.
3. the Traditional Chinese medicine tincture curing chilblain as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Ramulus Mori 10, Herba galii veri 9, Radix rubi coreani 11, Cortex Rhamni Globosae Radicis 8, Radix Alternantherae philoxeroidis 7, Rhizoma Begoniae Fimbristipulatae 6, Oleum Juglandis 9, Herba Euonymi Bungeani 8, Caulis et Folium Ammopiptanthi Mongolici 9, Fructus Herpetospermi pedunculosi 10.5, soda-apple nightshade herb 10, globule grass 8, Radix Strophanthi Divaricati 5, Herba vernoniae solanifoliae 6.5, Herba Lysimachiae Lobelioidis 8.5.
4. the preparation method of the Traditional Chinese medicine tincture of the treatment chilblain as described in as arbitrary in claims 1 to 3, it is characterized in that, step is as follows;
(1) by Ramulus Mori and Herba Euonymi Bungeani, removing impurity, adds 9-12 times amount rice water, and soak 2-4 hour, leach medicinal liquid, medicinal residues dry, and are ground into coarse powder, crosses 30 mesh sieves;
(2) by Herba galii veri, Radix rubi coreani, Radix Alternantherae philoxeroidis, Fructus Herpetospermi pedunculosi, soda-apple nightshade herb, globule grass and Herba Lysimachiae Lobelioidis mixing, be ground into coarse powder, be placed in vacuum drying oven, 60 DEG C of dry 9-13 hour, take out, be ground into coarse powder, cross 30 mesh sieves;
(3) by Cortex Rhamni Globosae Radicis, Rhizoma Begoniae Fimbristipulatae, Caulis et Folium Ammopiptanthi Mongolici, Radix Strophanthi Divaricati and Herba vernoniae solanifoliae removing impurity, clean, put in boiling water and boil 10-16 minute, the amount of boiling water is 13-18 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight, take out medicinal residues, grind coarser powder altogether, cross 30 mesh sieves;
(4) step (1), step (2) and step (3) gained coarse powder are mixed, add step (1) gained medicinal liquid, Oleum Juglandis and 70% ethanol, the amount of ethanol is that doubly (preferred, the amount of ethanol is 9-11 times of step (1), step (2) and step (3) gained coarse powder gross weight to the 8-12 of step (1), step (2) and step (3) gained coarse powder gross weight; Be more preferably, the amount of ethanol is 10 times of step (1), step (2) and step (3) gained coarse powder gross weight), sealing dipping 5-10 days, removes slag, to obtain final product.
5. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, is characterized in that, add 10-11 times amount rice water (preferably adding 10.5 times amount rice waters) in step (1).
6. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, is characterized in that, soaks 2.5-3.5 hour (preferably soaking 3 hours) in step (1).
7. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, is characterized in that, in step (2) dry 10-12 hour (preferably dry 11 hours).
8. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, is characterized in that, boil 12-15 minute (preferably put in boiling water and boil 14 minutes) in step (3) mid-boiling water.
9. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, it is characterized in that, in step (3) amount of boiling water be Rhizoma Begoniae Fimbristipulatae, the 15-17 of Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight doubly (amount of preferred boiling water is 16 times of Rhizoma Begoniae Fimbristipulatae, Herba vernoniae solanifoliae, Cortex Rhamni Globosae Radicis, Caulis et Folium Ammopiptanthi Mongolici and Cornu Caprae seu Ovis gross weight).
10. the preparation method curing the Traditional Chinese medicine tincture of chilblain as claimed in claim 4, is characterized in that, sealing dipping 6-9 days (preferably sealing dipping 8 days) in step (4).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108143922A (en) * | 2018-01-25 | 2018-06-12 | 黔西南州绿缘动植物科技开发有限公司 | A kind of pocket orchid medicament with anti-inflammatory analgetic and its preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048847A (en) * | 2009-11-09 | 2011-05-11 | 陈登 | Externally applied medicine for treating frostbite |
| CN102379988A (en) * | 2011-10-18 | 2012-03-21 | 安徽来福高科股份有限公司 | Snake medicinal liquor liniment for treating chilblain |
| CN104740544A (en) * | 2013-12-25 | 2015-07-01 | 孔祥涛 | Traditional Chinese medicine composition for treating chilblain |
-
2016
- 2016-01-08 CN CN201610009217.8A patent/CN105560581A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048847A (en) * | 2009-11-09 | 2011-05-11 | 陈登 | Externally applied medicine for treating frostbite |
| CN102379988A (en) * | 2011-10-18 | 2012-03-21 | 安徽来福高科股份有限公司 | Snake medicinal liquor liniment for treating chilblain |
| CN104740544A (en) * | 2013-12-25 | 2015-07-01 | 孔祥涛 | Traditional Chinese medicine composition for treating chilblain |
Non-Patent Citations (1)
| Title |
|---|
| 谷云飞: "《中医外科学图表解》", 31 January 2009, 人民卫生出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108143922A (en) * | 2018-01-25 | 2018-06-12 | 黔西南州绿缘动植物科技开发有限公司 | A kind of pocket orchid medicament with anti-inflammatory analgetic and its preparation method and application |
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Address after: 810000 Qilian District, Xining City, North Road, No. 361, Silver Garden District 3-2-601 Applicant after: Wang Fangcun Address before: 250000 Ji'nan Province, Lixia District, Shandong, by the way of the first phase of the kiln No. 3 building, unit 601, unit 2 Applicant before: Wang Fangcun |
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