CN103565723A - Application of tremella aurantialba extract in cosmetics - Google Patents
Application of tremella aurantialba extract in cosmetics Download PDFInfo
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- CN103565723A CN103565723A CN201210269169.8A CN201210269169A CN103565723A CN 103565723 A CN103565723 A CN 103565723A CN 201210269169 A CN201210269169 A CN 201210269169A CN 103565723 A CN103565723 A CN 103565723A
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Abstract
The invention discloses application of tremella aurantialba extract in cosmetics. The cosmetics are selected from moisturizing cosmetics, anti-inflammatory cosmetics with a moisturizing effect, anti-aging cosmetics with the moisturizing effect and skin whitening cosmetics with the moisturizing effect. The tremella aurantialba extract has the moisturizing effect, can be directly used for moisturizing skin and also can be used as an effect additive to be added into the cosmetics.
Description
Technical field
The present invention relates to Natural Medicine Chemistry field and cosmetic field, be specifically related to a kind of Tremella aurantialba Bandoni et Zang extract for moisturizing, its preparation method and the application in cosmetics thereof.The invention still further relates to the cosmetic composition that comprises Tremella aurantialba Bandoni et Zang extract.
Background technology
Skin is consisted of epidermis, corium and subcutaneus adipose tissue, and every layer all contains moisture.The number of moisture content of skin is tender, plentiful, the glossy and whether soft key of skin.The infant skin water content amount higher position delicate gloss that seems, old people's skin is because water content is lower, so seem dry, flat, the desquamation that withers, wrinkle occurs even.
Moisturizing is eternal theme, is the essential condition that guarantees skin health, slow down aging, and the wetting agent of developmental research excellent performance is the target that people seek assiduously.
On the one hand with age, skin moisture-keeping mechanism sustains damage, and skin tissue cell and intercellular moisture reduce, and when horny layer moisture drops to 10% when following, that skin will seem is dry, follow the string, wrinkling, acceleration skin aging.Skin suffers the infringements such as sweltering heat, cold, wind, cleaning agent, ultraviolet radiation on the other hand, and it is drier that top layer can become.Therefore how to keep the moisture of skin, reduce moisture loss very important.Skin moisturizer mainly comprises sealer, hygroscopic agent, hydrophilic matrix, preventing light agent and some special adding ingredients in the market.
Traditional medicine thinks, xerosis cutis is lung renal dysfunction, water liquid metabolic imbalance, and the not flourish skin of body fluid, therefore the road of skin moistening is invigorating the lung and the kidney, nourishing body fluid.In Chinese medicine document, also there is the record of skin-moisturizing, skin, and compiled Chinese medicine beauty treatment prescription, from theory into action, be all described.Some modern studies are set forth to some extent to the effect of polysaccharide component in recent years, the height water absorption of polysaccharide and good film property are perfectly in conjunction with reaching good moistening effect, be applied to just gradually skin moisture-keeping, and polysaccharide is also the contained main component of most edible fungi, these have all brought bright prospect for we find skin moisturizer safely and effectively.
China's Chinese medicine aboundresources, provides the foundation for we find superior moisturizing additive.Ancient medical book is recorded: Tremella aurantialba Bandoni et Zang, sweet in the mouth, property are flat, YIN nourishing, lung moistening, promote the production of body fluid, supplementing the brain; Cure mainly cough due to consumptive disease, hemoptysis, pulmonary tuberculosis.Tremella aurantialba Bandoni et Zang (Tremella aurantialba Bandoni et Zang), is Mycophyta door fungus, claims again Tremella mesenterica Retz ex Fr., luxuriant Ruo Seerbu (Tibetan language), golden yellow Tremella, yellow ear, brain ear.Tremella aurantialba Bandoni et Zang is a kind of Tibetan medicine, cures mainly Pulmonary Diseases.Tremella aurantialba Bandoni et Zang contains golden fungus polysaccharides, each seed amino acid, vitamin B group etc.Modern medicine research shows: Tremella aurantialba Bandoni et Zang is improved function of nervous system, adjusting body cell physiologically active, blood fat reducing, the liver protecting, raising hemopoietic function, improves the effects such as immunity.Tremella aurantialba Bandoni et Zang is a kind of edible fungi more precious than Tremella, and because yielding poorly, expensive, application person is less, knows that its person is also less.
The present invention is applied to Tremella aurantialba Bandoni et Zang extract in cosmetics, to provide moisture-keeping efficacy, helps skin to resist dry environment, prevents moisture loss, moisturizing skin Caring.
Summary of the invention
The object of the present invention is to provide a kind of Chinese herbal medicine Tremella aurantialba Bandoni et Zang with moisture-keeping function, this Tremella aurantialba Bandoni et Zang extract of making by the formula providing and preparation method, can be directly used in skin moisture-keeping.Tremella aurantialba Bandoni et Zang extract also can be used as functional additive and joins in cosmetics and use.
Tremella aurantialba Bandoni et Zang extract has moisture-keeping efficacy, can help skin under dry environment, to resist dry damage.Tremella aurantialba Bandoni et Zang extract, for cosmetics, is had to the effect of moisturizing skin Caring, make skin honorable moist.
Tremella aurantialba Bandoni et Zang is applied to food and medicine field mostly at present.But the inventor is through research discovery, Tremella aurantialba Bandoni et Zang extract also has remarkable skin Caring effect, can resist the moisture loss under dry environment, to reach moisture-keeping efficacy.
Therefore, an object of the present invention is to provide the application of Tremella aurantialba Bandoni et Zang extract in cosmetics.Specifically, the object of this invention is to provide the application of Tremella aurantialba Bandoni et Zang extract in the cosmetics for the preparation of moisturizing.
According to of the present invention one preferred embodiment, described cosmetics can be selected from: moisture-keeping cosmetics, have the anti-inflammatory cosmetics of moisture-keeping efficacy, have the anti-aging cosmetics of moisture-keeping efficacy or have the skin-lightening cosmetic of moisture-keeping efficacy.
According to of the present invention one preferred embodiment, described cosmetics can be following forms: fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection gel, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
According to of the present invention one preferred embodiment, described cosmetics also comprise the acceptable adjuvant of cosmetic field.According to of the present invention one preferred embodiment, the acceptable adjuvant of described cosmetic field is selected from: solvent, solubilizing agent, antiseptic, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
According in the preferred embodiment of the present invention, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be at least 0.001mg/ml, at least 0.01mg/ml, at least 0.015mg/ml.According in the preferred embodiment of the present invention, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 50mg/ml, at the most 40mg/ml, at the most 30mg/ml at the most, 20mg/ml, at the most 10mg/ml, at the most 5mg/ml at the most, 3mg/ml, at the most 2mg/ml, at the most 1.5mg/ml at the most.For example, one preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.001mg/ml to 50mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 40mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 30mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 20mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.015mg/ml to 10mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.015mg/ml to 5mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.015mg/ml to 2mg/ml.One preferred embodiment in, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.015mg/ml to 1.5mg/ml.
The Tremella aurantialba Bandoni et Zang extract obtaining prepared according to the methods of the invention can be directly used in skin moisture-keeping, also can be used as functional additive and joins in cosmetics and use.Therefore, according to another object of the present invention, the invention provides a kind of cosmetic composition, described compositions contains Tremella aurantialba Bandoni et Zang extract and the acceptable adjuvant of cosmetic field.
The acceptable adjuvant of described cosmetic field can be selected from: solvent, solubilizing agent, antiseptic, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
According to of the present invention one preferred embodiment, described compositions can be fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection gel, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.These forms can be prepared by method well known to those skilled in the art.
According to of the present invention one preferred embodiment, described Tremella aurantialba Bandoni et Zang extract accounts for the 0.001-100% of described composition total weight.One preferred embodiment in, described Tremella aurantialba Bandoni et Zang extract accounts for the 0.01-50% of described composition total weight, more preferably 0.5-20%, most preferably 0.1-5%.
Tremella aurantialba Bandoni et Zang extract of the present invention can be extracted and be obtained by method well known to those skilled in the art, and for example, depletion ear is appropriate, with suitable solvent, soaks, and with suitable extracting method, extracts, and filters and obtains supernatant liquid, also can volatilize solvent and make dry powder form.
According to of the present invention one preferred embodiment, suitable solvent is mainly water (comprising distilled water, deionized water etc.) or organic solvent (preferably alcohols and esters solvent); Suitable extraction and purification process be selected from following one or more: lixiviate, decoction, backflow, supercritical, precipitate with ethanol, extraction, membrance separation and column chromatography.
Tremella aurantialba Bandoni et Zang extract has moisture-keeping efficacy, can give skin keratin cell good moisture-keeping function, helps skin to keep moisture.After adding in cosmetics, there is the effect of moisturizing skin Caring, make skin honorable moist.
Accompanying drawing explanation
Fig. 1 has shown the comparison of moisturizing additive hyaluronate sodium (5mg/ml) moistening effect in different time sections that 1.5mg/ml Tremella aurantialba Bandoni et Zang extract, 0.15mg/ml Tremella aurantialba Bandoni et Zang extract, 0.015mg/ml Tremella aurantialba Bandoni et Zang extract and cosmetic field are conventional.
The specific embodiment
Unless otherwise defined, all technology used herein and scientific terminology have the common identical meanings of understanding of one skilled in the art of the present invention.Although can be used for implementing or testing the present invention to any method and material similar or that be equal to described herein, described herein is preferred method and material.For object of the present invention, defined following term below.
Term " about " used herein refers to compare with quantity, level, numerical value, dimension, size or the consumption of reference product, and difference can be up to 30%, 20% or 10% quantity, level, numerical value, dimension, size or consumption.
In full piece of writing description and claims, Unless Otherwise Requested, following word " comprises " and its variant " contains " and " comprising " is interpreted as meaning comprising described integral body or step, or one group of integral body or step, but do not get rid of any other integral body or step, or other one group of integral body or step.
According to the present invention, term " Tremella aurantialba Bandoni et Zang extract " refers to the extract that contains effective ingredient extracting from Tremella aurantialba Bandoni et Zang by any appropriate ways.
According to the present invention, term " cosmetics " refers to smear, sprays or other similar approach, intersperse among any position of human body surface, as skin, hair, refer to toenail, lips and teeth etc., to reach clean, maintain, improve looks, modify and to change outward appearance, or correction human scent, maintains a good state as chemical industrial product or the fine chemical product of object.According in the preferred embodiment of the present invention, described cosmetics comprise: moisture-keeping cosmetics, there are the anti-inflammatory cosmetics of moisture-keeping efficacy, and defying age or the skin-lightening cosmetic with moisture-keeping efficacy.
The present invention also provides a kind of cosmetic composition, it is characterized in that, described compositions contains Tremella aurantialba Bandoni et Zang extract and the acceptable adjuvant of cosmetic field.Described " the acceptable adjuvant of cosmetic field " can be selected from: solvent, solubilizing agent, antiseptic, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
According in the preferred embodiment of the present invention, described cosmetic composition can be the forms such as fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection gel, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or spraying.These forms of cosmetic composition can be prepared by method well known to those skilled in the art.
The present inventor is surprised to find that: Tremella aurantialba Bandoni et Zang extract has moisture-keeping efficacy, can be directly used in skin moisture-keeping, also can be used as functional additive and joins in cosmetic composition and use.The Tremella aurantialba Bandoni et Zang extract making according to the inventive method and the cosmetic composition that comprises Tremella aurantialba Bandoni et Zang extract, can help skin under dry environment, to resist dry damage, and moisturizing skin Caring makes skin honorable moist.
The working concentration of Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 20mg/ml.For example, the working concentration of Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 10mg/ml, preferably 0.015mg/ml to 5mg/ml.If added in cosmetics as additive, in the gross weight of cosmetic composition, described cosmetic composition can comprise the Tremella aurantialba Bandoni et Zang extract of 0.001-100%.In one of the present invention preferred embodiment, described Tremella aurantialba Bandoni et Zang extract accounts for the approximately 0.5-20% of described composition total weight.
Tremella aurantialba Bandoni et Zang (Tremella aurantialba Bandoni et Zang), is Mycophyta door fungus, claims again Tremella mesenterica Retz ex Fr., luxuriant Ruo Seerbu (Tibetan language), golden yellow Tremella, yellow ear, brain ear.Tremella aurantialba Bandoni et Zang is a kind of Tibetan medicine, cures mainly Pulmonary Diseases.Tremella aurantialba Bandoni et Zang contains golden fungus polysaccharides, each seed amino acid, vitamin B group etc.Modern medicine research shows: Tremella aurantialba Bandoni et Zang is improved function of nervous system, adjusting body cell physiologically active, blood fat reducing, the liver protecting, raising hemopoietic function, improves the effects such as immunity.Tremella aurantialba Bandoni et Zang is a kind of edible fungi more precious than Tremella, and because yielding poorly, expensive, application person is less, knows that its person is also less.
The modern study of Tremella aurantialba Bandoni et Zang is mainly concentrated on to its edible and medical value.Tremella aurantialba Bandoni et Zang contains abundant fat, and the trace element such as protein and phosphorus, sulfur, manganese, ferrum, magnesium, calcium, potassium, are a kind of tonic foods.The nourishing the human Body of Tremella aurantialba Bandoni et Zang is worth and is better than the colloid mushrooms such as Tremella, Auricularia, is a kind of desirable high level spindle dinner delicacies and health-care good product.Its medicinal function comprises: 1. improve organism metabolism function, the growth of inhibition tumor cell.2. regulate organism metabolism function, improve body nutriture, improve the content of body hemoglobin and blood plasma.3. improve body defying age, anti-anoxia ability, blood fat reducing, cholesterol reducing.4. promote liver lipid metabolism, prevent that fat from, in liver accumulation, improving liver detoxification function.Often eat illness prevention and fitness effectively, slow down aging.
In document, all do not relate to the application of Tremella aurantialba Bandoni et Zang extract in cosmetics, more not mentioned Tremella aurantialba Bandoni et Zang extract has moistening effect.Therefore, the present invention proposes first Tremella aurantialba Bandoni et Zang and has moisture-keeping efficacy, can be used as in the cosmetic composition that functional additive adds moisturizing, helps skin under dry environment, to resist dry damage, moisturizing skin Caring.
Tremella aurantialba Bandoni et Zang extract of the present invention can be extracted and be obtained by method well known to those skilled in the art, and for example, depletion ear is appropriate, with suitable solvent, soaks, and with suitable extracting method, extracts, and filters and obtains supernatant liquid, also can volatilize solvent and make dry powder form.
According to of the present invention one preferred embodiment, suitable solvent is mainly water (comprising distilled water, deionized water etc.) or organic solvent (preferably alcohols and esters solvent); Suitable extraction and purification process be selected from following one or more: lixiviate, decoction, backflow, supercritical, precipitate with ethanol, extraction, membrance separation and column chromatography.
Below in conjunction with specific embodiment, further set forth the present invention.But, should be understood that these embodiment only do not form limitation of the scope of the invention for the present invention is described.The test method of unreceipted actual conditions in the following example, conventionally according to normal condition, or the condition of advising according to manufacturer.Except as otherwise noted, all percentage ratio and umber are by mass.
Embodiment 1
The Tremella aurantialba Bandoni et Zang of getting pulverizing is appropriate, in impouring extraction pot, adds 40 times of amounts (W/V) water, and fully stirring and evenly mixing is incubated lixiviate 2 hours under 60 ℃ of conditions, filters, and discards filtering residue, and filtrate is gained.
Embodiment 2
The Tremella aurantialba Bandoni et Zang of getting pulverizing is appropriate, in impouring extraction pot, adds 20 times of amounts (W/V) water, and fully stirring and evenly mixing is incubated lixiviate 2 hours under 80 ℃ of conditions, and discontinuity stirs, and extracts 2 times; Filter, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.Slowly add while stirring 95% ethanol, making ethanol final concentration is 60～75%, hold over night.Filter, get supernatant, add ethyl acetate extraction 3 times, extract is flung to solvent, adds appropriate dissolve with ethanol.
Embodiment 3
The Tremella aurantialba Bandoni et Zang of getting pulverizing is appropriate, in impouring extraction pot, adds 20 times of amounts (W/V) water, and fully stirring and evenly mixing is incubated lixiviate 2 hours under 80 ℃ of conditions, and discontinuity stirs, and extracts 2 times; Filter, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.Slowly add while stirring 95% ethanol, making ethanol final concentration is 60～75%, hold over night.Filter, get filtering residue and under reduced pressure, reclaim ethanol extremely without alcohol taste, residue adds suitable quantity of water to dissolve.
Embodiment 4
The Tremella aurantialba Bandoni et Zang of getting pulverizing is appropriate, in impouring extraction pot, adds 20 times of amounts (W/V) water, abundant stirring and evenly mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-and boils 2 hours, extracts 2 times; Filter, discard filtering residue, merge filtrate 2 times, filtrate heating is concentrated into appropriate, the cooling rear centrifugal sediment that discards.Supernatant adds deionized water to mix in right amount, join in pretreated D101 macroporous resin column (purchased from Tianjin insecticide factory, preprocessing process: be dipped to for several times alcoholic solution with 95% ethanol and be clear, water rushes post extremely without ethanol taste again), first with distilled water, be eluted to closely colourlessly, then with 4 times of amount 50% ethanol elutions, collect ethanol elution, eluent concentrating under reduced pressure reclaims ethanol extremely without alcohol taste, and residual liquid adds suitable quantity of water to dissolve (also can add the appropriate hydrotropy of propylene glycol).
Embodiment 5
The Tremella aurantialba Bandoni et Zang of getting pulverizing is appropriate, in impouring extraction pot, adds 30 times of amounts (W/V) water, abundant stirring and evenly mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-and boils 2 hours, extracts 1～2 time; Filter, discard filtering residue, merge filtrate 2 times, upper membrane separation device (Xiamen Filter and Membrane Technology Co., Ltd., model: RNF-0460), regulate suitable pressure and flow, isolate the effective part group of molecular weight between 2000～200000 after cotton balls coarse filtration.
Embodiment 6: resist the moisture loss experiment under dry environment
The Tremella aurantialba Bandoni et Zang extract that the Tremella aurantialba Bandoni et Zang extract sample solution using in the present embodiment prepares for embodiment 1.
6.1. experimental principle
Water is to do eternal random motion by the molecular molecule of moisture.When in dry environment, hydrone easily moves in air, and now moisture has has just slowly scattered and disappeared.
6.2. experimental technique
For simulated skin state, select the microscope slide of 25.4 * 76.2mm, stick 3M adhesive tape.Tremella aurantialba Bandoni et Zang extract is configured to certain density aqueous solution, takes the sample of about 200mg, it is evenly applied on microscope slide, put into the instrument of constant temperature and humidity.This experiment is carried out under room temperature (25 ℃), adopts saturated ammonium sulfate solution to control 81% constant humidity environment.Certain hour is weighed after (30,60,90,120,150,180 minutes), and the percentage of water loss of calculation sample is carried out comparison moisturizing rate by the size of percentage of water loss, and the less expression moistening effect of percentage of water loss is better.
Percentage of water loss (%)=(M2-M3)/(M2-M1) * 100%
M1---microscope slide weight (g)
M2---smear the front gross weight (g) of rear placement
M3---smear gross weight (g) after rear placement
In experiment, for understanding the moisture-keeping efficacy of Tremella aurantialba Bandoni et Zang extract, select hyaluronate sodium as positive control.Hyaluronic acid (Hyaluronic acid) is a kind of macromolecule mucopolysaccharide that is construction unit by D-N-acetylglucosamine and D-Glucose aldehydic acid, and commodity hyaluronic acid is generally its sodium salt, i.e. hyaluronate sodium (Sodium Hyaluronate).Hyaluronic acid is the bio-molecules extensively existing in skin and other tissue, has fabulous moisture-keeping function, is called as desirable nature moisturizing factor (Natural MolsturlZlng Factor, NMF).
Confirm by experiment, Tremella aurantialba Bandoni et Zang extract has obvious maintenance, prevents the effect of moisture loss.Compare with generally acknowledged moisturizing raw material hyaluronate sodium, under lower working concentration, can bring into play better moistening effect.As can be seen here, Tremella aurantialba Bandoni et Zang extract has moisture-keeping efficacy, is expected to become a kind of new and effective cosmetics moisturizing raw material.
Claims (8)
1. the application of Tremella aurantialba Bandoni et Zang extract in cosmetics.
2. application as claimed in claim 1, is characterized in that, described cosmetics are selected from: moisture-keeping cosmetics, have the anti-inflammatory cosmetics of moisture-keeping efficacy, have the anti-aging cosmetics of moisture-keeping efficacy or have the skin-lightening cosmetic of moisture-keeping efficacy.
3. application as claimed in claim 1, is characterized in that, described cosmetics are following forms: fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection gel, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
4. application as claimed in claim 1, is characterized in that, described cosmetics also comprise the acceptable adjuvant of cosmetic field.
5. application as claimed in claim 4, it is characterized in that, the acceptable adjuvant of described cosmetic field is selected from: solvent, solubilizing agent, antiseptic, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
6. application as claimed in claim 1, is characterized in that, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 20mg/ml.
7. application as claimed in claim 6, is characterized in that, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.01mg/ml to 10mg/ml.
8. application as claimed in claim 6, is characterized in that, the working concentration of described Tremella aurantialba Bandoni et Zang extract can be 0.015mg/ml to 5mg/ml.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103976923A (en) * | 2014-05-31 | 2014-08-13 | 广州千百度化妆品有限公司 | Japanese saussurea herb extracting solution as well as preparation method and application thereof |
| CN104758320A (en) * | 2015-01-29 | 2015-07-08 | 黄豆粧 | A preparation method of moisturizing medicine for coating and application of the moisturizing medicine |
| CN105534811A (en) * | 2016-01-19 | 2016-05-04 | 中山百鸥医药科技有限公司 | Emollient cream and preparation method thereof |
| CN105769657A (en) * | 2016-03-03 | 2016-07-20 | 厦门中妍生物科技有限公司 | Skin care product mainly prepared from Tibetan medicine black fungus and preparation method thereof |
| CN113876614A (en) * | 2021-10-11 | 2022-01-04 | 广州萃普生物科技有限公司 | Glycyrrhizic anhydride and tremella polysaccharide degradation product compound composition and application thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103976923A (en) * | 2014-05-31 | 2014-08-13 | 广州千百度化妆品有限公司 | Japanese saussurea herb extracting solution as well as preparation method and application thereof |
| CN103976923B (en) * | 2014-05-31 | 2016-07-06 | 广州千百度化妆品有限公司 | A kind of Herba Saussuseae Japonicae extracting solution and its preparation method and application |
| CN104758320A (en) * | 2015-01-29 | 2015-07-08 | 黄豆粧 | A preparation method of moisturizing medicine for coating and application of the moisturizing medicine |
| CN105534811A (en) * | 2016-01-19 | 2016-05-04 | 中山百鸥医药科技有限公司 | Emollient cream and preparation method thereof |
| CN105769657A (en) * | 2016-03-03 | 2016-07-20 | 厦门中妍生物科技有限公司 | Skin care product mainly prepared from Tibetan medicine black fungus and preparation method thereof |
| CN105769657B (en) * | 2016-03-03 | 2018-11-09 | 厦门中妍生物科技有限公司 | One kind is with Tibetan medicine material black fungus skin care item as main component and preparation method thereof |
| CN113876614A (en) * | 2021-10-11 | 2022-01-04 | 广州萃普生物科技有限公司 | Glycyrrhizic anhydride and tremella polysaccharide degradation product compound composition and application thereof |
| CN113876614B (en) * | 2021-10-11 | 2023-05-02 | 广州萃普生物科技有限公司 | Glycyrrhizin and tremella aurantialba polysaccharide degradation product compound composition and application thereof |
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