CN103550123A - Chinese medicinal toothpaste containing pseudo-ginseng total saponins and saponin extracts and tortoise shell extracts - Google Patents
Chinese medicinal toothpaste containing pseudo-ginseng total saponins and saponin extracts and tortoise shell extracts Download PDFInfo
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- CN103550123A CN103550123A CN201310546270.8A CN201310546270A CN103550123A CN 103550123 A CN103550123 A CN 103550123A CN 201310546270 A CN201310546270 A CN 201310546270A CN 103550123 A CN103550123 A CN 103550123A
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- 239000000284 extract Substances 0.000 title claims abstract description 59
- 229930182490 saponin Natural products 0.000 title claims abstract description 33
- 150000007949 saponins Chemical class 0.000 title claims abstract description 33
- 235000017709 saponins Nutrition 0.000 title claims abstract description 33
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 25
- 239000000606 toothpaste Substances 0.000 title claims abstract description 25
- 241000270708 Testudinidae Species 0.000 title abstract description 4
- 244000131316 Panax pseudoginseng Species 0.000 title abstract 3
- 235000003181 Panax pseudoginseng Nutrition 0.000 title abstract 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 title abstract 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 44
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 15
- 239000004698 Polyethylene Substances 0.000 claims abstract description 15
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims abstract description 15
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 15
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 15
- -1 polyethylene Polymers 0.000 claims abstract description 15
- 229920000573 polyethylene Polymers 0.000 claims abstract description 15
- 229940085605 saccharin sodium Drugs 0.000 claims abstract description 15
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 15
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims abstract description 15
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 14
- 239000000600 sorbitol Substances 0.000 claims abstract description 14
- 239000000679 carrageenan Substances 0.000 claims abstract description 11
- 235000010418 carrageenan Nutrition 0.000 claims abstract description 11
- 229920001525 carrageenan Polymers 0.000 claims abstract description 11
- 229940113118 carrageenan Drugs 0.000 claims abstract description 11
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims abstract description 11
- 235000010234 sodium benzoate Nutrition 0.000 claims abstract description 11
- 239000004299 sodium benzoate Substances 0.000 claims abstract description 11
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims abstract description 11
- 229920002907 Guar gum Polymers 0.000 claims abstract description 10
- 239000000665 guar gum Substances 0.000 claims abstract description 10
- 235000010417 guar gum Nutrition 0.000 claims abstract description 10
- 229960002154 guar gum Drugs 0.000 claims abstract description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 39
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 28
- 241000180649 Panax notoginseng Species 0.000 claims description 28
- 239000008367 deionised water Substances 0.000 claims description 9
- 229910021641 deionized water Inorganic materials 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 8
- 239000013538 functional additive Substances 0.000 claims description 6
- 230000008719 thickening Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 7
- 229910052791 calcium Inorganic materials 0.000 abstract description 7
- 239000011575 calcium Substances 0.000 abstract description 7
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- 238000000034 method Methods 0.000 abstract description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract description 3
- 208000002064 Dental Plaque Diseases 0.000 abstract description 3
- 206010018275 Gingival atrophy Diseases 0.000 abstract description 3
- 208000032843 Hemorrhage Diseases 0.000 abstract description 3
- 201000005562 gingival recession Diseases 0.000 abstract description 3
- 208000007565 gingivitis Diseases 0.000 abstract description 3
- 201000001245 periodontitis Diseases 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
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- 210000000988 bone and bone Anatomy 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 abstract description 2
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- 241000894006 Bacteria Species 0.000 abstract 1
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- 230000000740 bleeding effect Effects 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- SOROIESOUPGGFO-UHFFFAOYSA-N diazolidinylurea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 abstract 1
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- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000003756 stirring Methods 0.000 description 9
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- 206010053567 Coagulopathies Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000533849 Gleditsia Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
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- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229930182486 flavonoid glycoside Natural products 0.000 description 1
- 150000007955 flavonoid glycosides Chemical class 0.000 description 1
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- 150000002989 phenols Chemical class 0.000 description 1
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- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention relates to Chinese medicinal toothpaste containing pseudo-ginseng total saponins and saponin extracts and tortoise shell extracts. The Chinese medicinal toothpaste comprises effective additives and matrix ingredients, wherein the effective additives comprise the pseudo-ginseng total saponins and saponin extracts and the tortoise shell extracts; the matrix ingredients comprise silicon dioxide, sorbitol, propanediol, polyethylene glycol-32, cellulose gum, carrageenan or guar gum, sodium lauryl sulfate, saccharin sodium, essences, Germall II or sodium benzoate and the balance being water. By virtue of a compounding technique, the Chinese medicinal toothpaste has a basic cleaning function and remarkable effects in the aspects of bacteria resisting, inflammation diminishing, bleeding stopping, swelling decrease, gingival nourishing and the like, can well prevent and alleviate multiple common oral cavity problems of gingivitis, gingival redness and swelling, gingival bleeding, dental plaque, periodontitis, gingival atrophy, gomphiasis and the like and further has the functions of regulating the calcium balance of teeth and bones and strengthening teeth.
Description
Technical field
The present invention relates to a kind of Chinese medicinal toothpaste, containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract, Carapax Et Plastrum Testudinis extract specifically, can there be prevention and effect to alleviate the multiple oral problem such as gingivitis, red swelling of gingiva are hemorrhage, dental plaque, periodontitis, gingival atrophy, odontoseisis, regulate the Chinese medicinal toothpaste of tooth skeletal calcium balance, firm tooth.
Background technology
Radix Notoginseng total saponins is the main effective ingredient of Radix Notoginseng, has good dissolubility in aqueous solution, at low concentration, does not have hemolytic, and safety is good.Modern study shows, Radix Notoginseng total saponins has the effect of the time that heart tonifying, strong anti-oxidation, vasoconstrictive, shortening clotting time and thrombin form, and invigorating blood circulation, aspect hemostasis, anti-inflammatory analgesic, application is wider.
Fructus Gleditsiae Abnormalis extract mainly contains flavonoid glycoside, phenols, aminoacid etc., and Fructus Gleditsia has natural inhibition and the effect of sterilization to a lot of antibacterials, fungus, not only can external sterilize, conduct germ killing drugs for oral administration that also can be safe.With it, treat in laryngopharynx swelling and pain, toothache due to pathogenic wind-heat, wind toothache, odontopathy clinically and pant etc., effect is very good.
Carapax Et Plastrum Testudinis extract is the effective ingredient extracting from the sternite of Testudinidae animal Testudinis and carapace, main organic colloid containing being comprised of protein, aminoacid, and the composition such as microelements of calcium, strontium, silicon dioxide, zinc, copper.There are enriching yin and nourishing kidney, nourish blood, the effect of hemostasis, strengthening the tendons and bones.There are some researches show, Carapax Et Plastrum Testudinis extract can activate retinoic acid receptors, and (expression of RAR α, vitamin D receptor (VDR) in vivo, propagation and the differentiation of outer promotion mesenchymal stem cells MSCs (MSC), regulates calcium balance and bone metabolism.
Chinese herbal toothpaste is in the market of a great variety, but with regard to retrieval situation, yet there are no and in toothpaste, adopt Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract, Carapax Et Plastrum Testudinis extract synergism as functional components such as antibiotic, antiinflammatory, analgesia, adjusting tooth skeletal calcium balance, firm teeth simultaneously.
Summary of the invention
The object of the invention is to utilize the synergism of Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract, a kind of more effective Chinese medicinal toothpaste that integrates the effects such as antibiotic, antiinflammatory, analgesia, adjusting tooth skeletal calcium balance, firm tooth is provided.
Chinese medicinal toothpaste containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract of the present invention, in toothpaste component, comprises functional additive and base material composition; It is characterized in that: described functional additive comprises Radix Notoginseng total saponins 0.005～0.5% Fructus Gleditsiae Abnormalis extract 0.05～1.5%, Carapax Et Plastrum Testudinis extract 0.05～1.5%; Described base material comprises silica 1 0～30%, sorbitol 40～70%, propylene glycol 1～10%, Polyethylene Glycol-32 0.1～1.5%, cellulose gum 0.1～1.5%, carrageenan 0.1～1.0% or guar gum 0.1～1.0%, sodium lauryl sulfate 1～5%, saccharin sodium 0.1～0.5%, essence 0.5～2.0%, germall B or sodium benzoate 0.1～0.5%, deionized water 10 ~ 30%.
Chinese medicinal toothpaste containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract of the present invention, is characterized in that: the best in quality percentage ratio of described whole compositions has 2 kinds of combinations:
The first combination, Radix Notoginseng total saponins 0.03～0.3%, Fructus Gleditsiae Abnormalis extract 0.1～1.0%, Carapax Et Plastrum Testudinis extract 0.1～1.0%, silica 1 5～25%, sorbitol 55～65%, propylene glycol 2～6%, Polyethylene Glycol-32 0.5～1.0%, cellulose gum 0.1～1.0%, carrageenan 0.2～0.5%, sodium lauryl sulfate 2～3%, saccharin sodium 0.2～0.3%, essence 1.0～1.5%, germall B or sodium benzoate 0.2～0.3%, surplus is water.
The second combination, Radix Notoginseng total saponins 0.03～0.3%, Fructus Gleditsiae Abnormalis extract 0.1～1.0%, Carapax Et Plastrum Testudinis extract 0.1～1.0%, silica 1 5～25%, sorbitol 45～55%, propylene glycol 4～10%, Polyethylene Glycol-32 0.5～1.0%, cellulose gum 0.1～1.0%, guar gum 0.3～0.6%, sodium lauryl sulfate 2～3%, saccharin sodium 0.2～0.3%, essence 1.0～1.5%, germall B or sodium benzoate 0.2～0.3%, surplus is water.
Chinese medicinal toothpaste containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract of the present invention, described silicon dioxide is comprised of friction-type silicon dioxide and thickening type silicon dioxide.
The above-mentioned Chinese medicinal toothpaste containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract, the manufacture method of its lotion of toothpaste is as follows: with part water, dissolve in advance saccharin sodium, functional additive (Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract), Polyethylene Glycol-32, germall B or sodium benzoate etc., obtain mixed aqueous solution, stand-by; In silicon dioxide, add cellulose gum, carrageenan or guar gum, sodium lauryl sulfate etc., and mix homogeneously, mixed material obtained; The water of sorbitol, propylene glycol and remaining part is joined in cream pot processed, then the mixed aqueous solution that adds saccharin sodium, functional additive, Polyethylene Glycol-32 and antiseptic, stir, and then add the mixed material of silicon dioxide, cellulose gum, carrageenan or guar gum, sodium lauryl sulfate, stir, finally add essence, homogenizing agitation grinding, degassed.Prepared by mastic.
Of the present invention containing Radix Notoginseng total saponins, the Chinese medicinal toothpaste of Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract, by compounded technology, in toothpaste, add Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract, the effect ingredients such as Carapax Et Plastrum Testudinis extract, make Chinese medicinal toothpaste of the present invention both there is cleaning teeth effect, there is again anti-inflammation simultaneously, hemostatic analgesia, regulate skeletal calcium balance, balance oral environment, the effects such as conditioning oral icrocirculation, to common gingivitis, red swelling of gingiva is hemorrhage, dental plaque, periodontitis, gingival atrophy, the multiple oral problem such as odontoseisis has good prevention and improves effect.
The specific embodiment
Below in conjunction with embodiment, the Chinese medicinal toothpaste containing Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract of the present invention is described further.
Implement formula 1:
Radix Notoginseng total saponins 0.05%, Fructus Gleditsiae Abnormalis extract 0.5%, Carapax Et Plastrum Testudinis extract 0.5%, silicon dioxide 20%, sorbitol 60%, propylene glycol 3%, Polyethylene Glycol-32 0.5%, cellulose gum 0.4%, carrageenan 0.3%, sodium lauryl sulfate 2.5%, saccharin sodium 0.25%, essence 1.2%, germall B 0.2%, surplus is deionized water.
Implement formula 2:
Radix Notoginseng total saponins 0.2%, Fructus Gleditsiae Abnormalis extract 0.1%, Carapax Et Plastrum Testudinis extract 0.1%, silica 1 8%, sorbitol 64%, propylene glycol 2%, Polyethylene Glycol-32 0.5%, cellulose gum 0.7%, carrageenan 0.2%, sodium lauryl sulfate 2.3%, saccharin sodium 0.23%, essence 1.0%, sodium benzoate 0.2%, surplus is deionized water.
Implement formula 3:
Radix Notoginseng total saponins 0.03%, Fructus Gleditsiae Abnormalis extract 1.0%, Carapax Et Plastrum Testudinis extract 1.0%, silicon dioxide 20%, sorbitol 55%, propylene glycol 5%, Polyethylene Glycol-32 0.8%, cellulose gum 0.7%, carrageenan 0.3%, sodium lauryl sulfate 2.8%, saccharin sodium 0.3%, essence 1.3%, germall B 0.2%, surplus is deionized water.
Implement formula 4:
Radix Notoginseng total saponins 0.05%, Fructus Gleditsiae Abnormalis extract 0.5%, Carapax Et Plastrum Testudinis extract 0.5%, silicon dioxide 20%, sorbitol 40%, propylene glycol 8%, Polyethylene Glycol-32 1.0%, cellulose gum 0.8%, guar gum 0.5%, sodium lauryl sulfate 2.6%, saccharin sodium 0.23%, essence 1.1%, sodium benzoate 0.3%, surplus is deionized water.
Implement formula 5:
Radix Notoginseng total saponins 0.1%, Fructus Gleditsiae Abnormalis extract 1.0%, Carapax Et Plastrum Testudinis extract 1.0%, silicon dioxide 20%, sorbitol 50%, propylene glycol 4%, Polyethylene Glycol-32 0.5%, cellulose gum 0.8%, guar gum 0.3%, sodium lauryl sulfate 2.4%, saccharin sodium 0.25%, essence 1.2%, germall B 0.3%, surplus is deionized water.
Manufacture method is:
(1) by above-mentioned formula 1～5 ratio requirement, take raw material;
(2) part deionized water is poured in premix pot;
(3) Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract, Carapax Et Plastrum Testudinis extract, saccharin sodium, Polyethylene Glycol-32, germall B or sodium benzoate are poured in premix pot, opened the stirring of premix pot until material dissolution obtains mixed aqueous solution;
(4) cellulose gum, carrageenan or guar gum, sodium lauryl sulfate, silicon dioxide are added in powder premix pot, open and stir until mix homogeneously;
(5) sorbitol, propylene glycol and remainder deionized water are added in cream pot processed;
(6) mixed aqueous solution in (3) is added in cream pot processed, open stirring scratch board material stirring in pot is even;
(7) mixed material in (4) is added in cream pot processed, in adition process, continue to stir;
(8) essence is added in cream pot processed;
(9) under vacuum condition, open homogenizing and scraper plate stirring, homogenizing grinding 15～20 minutes, degassed;
(10) stop stirring, proportion is surveyed in sampling, the qualified rear sample presentation chemical examination of proportion;
(11) sample presentation result of laboratory test all reaches standard-required, prepared by mastic.
Claims (4)
1. containing a Chinese medicinal toothpaste for Radix Notoginseng total saponins, Fructus Gleditsiae Abnormalis extract and Carapax Et Plastrum Testudinis extract, toothpaste component comprises functional additive and base material composition; It is characterized in that: described functional additive comprises Radix Notoginseng total saponins 0.005～0.5% Fructus Gleditsiae Abnormalis extract 0.05～1.5%, Carapax Et Plastrum Testudinis extract 0.05～1.5%; Described base material comprises silica 1 0～30%, sorbitol 40～70%, propylene glycol 1～10%, Polyethylene Glycol-32 0.1～1.5%, cellulose gum 0.1～1.5%, carrageenan 0.1～1.0% or guar gum 0.1～1.0%, sodium lauryl sulfate 1～5%, saccharin sodium 0.1～0.5%, essence 0.5～2.0%, germall B or sodium benzoate 0.1～0.5%, deionized water 10 ~ 30%.
2. Chinese medicinal toothpaste according to claim 1, is characterized in that:
The best in quality percentage ratio of described whole compositions is: Radix Notoginseng total saponins 0.03～0.3%, Fructus Gleditsiae Abnormalis extract 0.1～1.0%, Carapax Et Plastrum Testudinis extract 0.1～1.0%, silica 1 5～25%, sorbitol 55～65%, propylene glycol 2～6%, Polyethylene Glycol-32 0.5～1.0%, cellulose gum 0.1～1.0%, carrageenan 0.2～0.5%, sodium lauryl sulfate 2～3%, saccharin sodium 0.2～0.3%, essence 1.0～1.5%, germall B or sodium benzoate 0.2～0.3%, surplus is water.
3. Chinese medicinal toothpaste according to claim 1, is characterized in that:
The best in quality percentage ratio of described whole compositions is: Radix Notoginseng total saponins 0.03～0.3%, Fructus Gleditsiae Abnormalis extract 0.1～1.0%, Carapax Et Plastrum Testudinis extract 0.1～1.0%, silica 1 5～25%, sorbitol 45～55%, propylene glycol 4～10%, Polyethylene Glycol-32 0.5～1.0%, cellulose gum 0.1～1.0%, guar gum 0.3～0.6%, sodium lauryl sulfate 2～3%, saccharin sodium 0.2～0.3%, essence 1.0～1.5%, germall B or sodium benzoate 0.2～0.3%, surplus is water.
4. according to the Chinese medicinal toothpaste described in claims 1 to 3, it is characterized in that: described silicon dioxide is comprised of friction-type silicon dioxide and thickening type silicon dioxide.
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| CN201310546270.8A CN103550123A (en) | 2013-11-07 | 2013-11-07 | Chinese medicinal toothpaste containing pseudo-ginseng total saponins and saponin extracts and tortoise shell extracts |
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| CN201310546270.8A CN103550123A (en) | 2013-11-07 | 2013-11-07 | Chinese medicinal toothpaste containing pseudo-ginseng total saponins and saponin extracts and tortoise shell extracts |
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| CN103550123A true CN103550123A (en) | 2014-02-05 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825368A (en) * | 2015-05-26 | 2015-08-12 | 陈琳仁 | Natural plant active toothpaste and preparation method thereof |
| CN106420444A (en) * | 2016-09-07 | 2017-02-22 | 文山金七药业有限公司 | Morning-use toothpaste and preparation method thereof |
| CN107334684A (en) * | 2017-08-01 | 2017-11-10 | 何家平 | A kind of China rose children Chinese herbal toothpaste technique |
| CN111686028A (en) * | 2019-04-26 | 2020-09-22 | 山东丁马生物科技有限公司 | Turtle collagen peptide toothpaste and preparation method thereof |
Citations (2)
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| CN1823721A (en) * | 2006-01-09 | 2006-08-30 | 张英强 | Compounding of peony natural organic compound series tooth paste product and its preparation method |
| CN103222947A (en) * | 2013-05-08 | 2013-07-31 | 苏敏华 | Traditional Chinese medicinal composition for treating periodontitis |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825368A (en) * | 2015-05-26 | 2015-08-12 | 陈琳仁 | Natural plant active toothpaste and preparation method thereof |
| CN106420444A (en) * | 2016-09-07 | 2017-02-22 | 文山金七药业有限公司 | Morning-use toothpaste and preparation method thereof |
| CN107334684A (en) * | 2017-08-01 | 2017-11-10 | 何家平 | A kind of China rose children Chinese herbal toothpaste technique |
| CN111686028A (en) * | 2019-04-26 | 2020-09-22 | 山东丁马生物科技有限公司 | Turtle collagen peptide toothpaste and preparation method thereof |
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