CN103520262B - A kind of lipid soluble gynecological gel - Google Patents
A kind of lipid soluble gynecological gel Download PDFInfo
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- CN103520262B CN103520262B CN201310489982.0A CN201310489982A CN103520262B CN 103520262 B CN103520262 B CN 103520262B CN 201310489982 A CN201310489982 A CN 201310489982A CN 103520262 B CN103520262 B CN 103520262B
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- 150000002632 lipids Chemical class 0.000 title claims abstract description 12
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- 239000011782 vitamin Substances 0.000 claims abstract description 11
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- 235000013343 vitamin Nutrition 0.000 claims abstract description 11
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- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims abstract description 10
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims abstract description 10
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- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of lipid soluble gynecological gel, be made up of following raw materials by weight portion: Ascorbyl Palmitate 8 ~ 15 parts, Fructus Cnidii 10 ~ 23 parts, Radix Sophorae Flavescentis 7 ~ 17 parts, Borneolum Syntheticum 2 ~ 8 parts, vitamin e 2 ~ 6 parts.The present invention without hormone, hurtless measure, non-stimulated, have no side effect, treating gynopathic while, rebuild reproductive tract environment, regeneration profitable strain, removes the fat-soluble toxins in health, promotes autoimmune function, uses more convenient safer.
Description
Technical field
The present invention relates to one and treat gynopathic medicine, be specifically related to a kind of medicine for the treatment of female genital tract infection.
Background technology
Reproductive tract infection is serious harm women's health " implicit type killer ", is to cause the chronic major gynecological disease " arch-criminal " of women, is the maximum enemy of women's health.The basic reason causing reproductive tract infection is the various conditioned pathogens easily hidden in inside and outside pudendum, as staphylococcus, streptococcus, escherichia coli, anaerobe, the pathogen that spreads through sex intercourse, Candida albicans and mycoplasma, chlamydia etc.When the change of human body internal and external environment during disequilibrium, pathogen will be staged an armed rebellion in an opponent's defence.Due to the shy psychological factor such as with privacy, women, when suffering from gynaecopathia and reproductive tract infection, mostly selects to go to pharmacy to purchase medicine and goes home to use, and non-serious illness does not go to regular medical institutions to go to a doctor.
China's gynecological external use medicine comprises Chinese patent medicine, antibiotic, chemosterilant and Chinese medicine and western medicine mixture etc., and wherein chemosterilant gynecological external use medicine market dominate at home, Chinese medicine and western medicine mixture at home retail market occupies leading position.Although chemosterilant instant effect, the toxic and side effects such as corrosivity are relatively large, the feature of None-identified " enemy and we ", make it while killing pathogenic bacteria, also kill probiotics, destroy the balance of intravaginal flora, cause that inflammation relapse rate is high, refractory is more after recurrence; Chinese medicine and western medicine mixture utilizes the sterilization of chemical composition to take stopgap measures, and utilizes Chinese medicine ingredients to effect a permanent cure, and is a kind of method for the treatment of both the principal and secondary aspects of a disease, but most product weak curative effect, the state of an illness is easily repeatedly; Antibiotic easily produces drug resistance, once generation Resistant strain, even if constantly increase drug dose, the state of an illness also can not get effective control, in addition, antibiotic destructible vaginal microbial flora balances, and uses rear inflammation relapse rate high, investigation shows: use in the women of a kind of powerful antibiotic more than one week, have the people of nearly half fungal infection can occur; Chinese patent medicine have drug effect gentleness, side effect little, meet the advantages such as China women medication custom for a long time, several years ago occuping market leading position, but Chinese medicine preparation ubiquity drug effect is comparatively slow, the problem that the treatment phase is relatively grown.
In addition, novel formulation nanometer silver is because having strong suppression and killing action to tens of kinds of pathogenic microorganism such as escherichia coli, gonococcus, chlamydia trachomatiss, and can not produce the features such as drug resistance be widely used in life in, comprising gynaecology external-use drug and articles for babies.But Korean science man finds in the recent period to eat and can work the mischief to liver into nano silver particles, and namely the liver toxicity of nanometer silver can not be ignored.
At present, the external drug dosage forms for the treatment of gynecological inflammation is of a great variety, is mainly divided into suppository class, lotion class, spray class and effervescent tablet class etc.These dosage forms use inconvenient, and administering mode is unhygienic, easily because improper operation causes cross infection.
In sum, it is unreasonable to there is prescription compatibility of medicines in domestic gynecological external use product, and dosage form uses inconvenient, the problems such as administering mode is unhygienic, and curative effect is not obvious.Therefore, seeking new more reasonably compatibility, improve the curative effect for the treatment of gynecological inflammation, is the emphasis and the direction that need to continue further investigation.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, a kind of lipid soluble gynecological gel easy to use, safe is provided.
For achieving the above object, the technical solution used in the present invention is: a kind of lipid soluble gynecological gel, is made up of following raw materials by weight portion: Ascorbyl Palmitate 8 ~ 15 parts, Fructus Cnidii 10 ~ 23 parts, Radix Sophorae Flavescentis 7 ~ 17 parts, Borneolum Syntheticum 2 ~ 8 parts, vitamin e 2 ~ 6 parts.
Above-mentioned a kind of lipid soluble gynecological gel, is made up of following raw materials by weight portion: Ascorbyl Palmitate 12 parts, Fructus Cnidii 15 parts, Radix Sophorae Flavescentis 12 parts, Borneolum Syntheticum 5 parts, vitamin e 4 parts.
Ascorbyl Palmitate (being called for short L-AP): the character with extremely strong non-oxidizability, the nearly water of lipophilic, the tide that do not keep in dark place, is not afraid of; Molecule is little, and decomposition temperature is high, and energy quick penetration cell membrane, fat-soluble toxins in scavenger cell, retains 36-48 hour, and availability is higher.L-AP also has extremely strong biological anti-inflammatory simultaneously; energy available protecting profitable strain; the ability of leukocytes phagocytic antibacterial and virus in reinforcement; strengthen the defensive ability/resistance ability to antibacterial, virus; alleviate the pain that human body causes because of a variety of causes; prevention is harmful to be infected, and quickly-healing wound, promotes detoxification ability.Utilize the property of L-AP, the source of disease hidden for many years by human body is excavated one by one, clears up, is excreted, and fundamentally recovers the normal physiological function of cell, has the health on practical significance.
After effective ingredient L-AP enters vagina, quickly move through the cutaneomucosal intercellular substance of table enter cell interior with its liposoluble characteristic, useful effect is in the rotten to the corn position of inflammation, play putrefaction-removing granulation-promoting, promote meat dental tissue hypertrophy, improve and create and microcirculation, make the effect that damaged tissue is repaired rapidly.
Fructus Cnidii: another name Daucus carota L., warm in nature, acrid in the mouth, hardship.Function cures mainly: warming the kidney to invigorate YANG, and dampness is dispeled the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Radix Sophorae Flavescentis: the plant belonged to for pulse family Radix Sophorae Flavescentis.Function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Borneolum Syntheticum: being the resin of Spore density Borneolum Syntheticum and the crystallization of volatile oil processed goods extraction acquisition, is near pure dextro Borneolum Syntheticum.Can be used for for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, to swell and ache for skin infection, do not hold back after bursting.
Vitamin e: a kind of fatsoluble vitamin is one of topmost antioxidant.
The present invention, by Ascorbyl Palmitate, is also aided with Fructus Cnidii, Borneolum Syntheticum, Radix Sophorae Flavescentis and vitamin e, to reach the effect for the treatment of both the principal and secondary aspects of a disease in use.L-AP has obvious fat-soluble antiinflammation, and infiltrate hypodermic layer fast, molecule is little, and molecular weight is large, and decomposition temperature is high, and VE and L-AP belongs to liposoluble substance together, extremely strong antioxidation; Radix Sophorae Flavescentis, Fructus Cnidii belong to water-soluble substances together, have direct antipyretic and itching-stopping antiinflammation to skin surface, and compatibility L-AP and VE permeates the dark lower floor of epidermis, antiphlogistic antibacterial, and the intervention of Borneolum Syntheticum regulates the decomposition temperature high phenomenon of liposoluble substance.Water solublity and fat-soluble dual its effect of antiinflammatory compatibility are more than the antiinflammation of water-soluble substances far away, and the vulvar mucous membrane inflammation antibiotic rate caused the infection secondary of female genital tract can up to 90%.
The present invention without hormone, hurtless measure, non-stimulated, have no side effect, the present invention is treatment vaginitis, cervicitis, HPV viral infection etc. are gynopathic while, rebuild reproductive tract environment, regeneration profitable strain, remove the fat-soluble toxins in health, promote autoimmune function, the wound that human body produces is repaired, do not produce drug resistance, use more convenient safer.
A kind of lipid soluble gynecological gel of the present invention is used for clinical situation
(1) physical data: vaginitis patient 120 example, wherein bacterial vaginitis 43 example, mycotic vagina 41 is scorching, trichomonal vaginitis 36 example.
(2) diagnostic criteria:
Symptom: leucorrhoea grow in quantity, has taste, pruritus vulvae, with burn feeling, pain and sexual anhedonia, during as companion's urinary tract infection, can have frequent micturition, urgent micturition, dysurea or hematuria.
The visible infusorian of difference or antibacterial when infusorian or bacterial vaginitis patient vaginal secretions microscopy, during mycotic vagina vaginal secretions microscopy (+), bacterial vaginitis BV checks the positive.
(3) Therapeutic Method:
With the material rate of embodiment 2 preparation gel, during use, administration can be facilitated at patient's tract, change dressings every day once, each one, often prop up 4g, continuous 10 days.
(4) efficacy assessment standard:
Cure: subjective symptoms disappears, vagina cleanness degree (I), vaginal swab is cultivated and is turned out cloudy;
Take a turn for the better: subjective symptoms alleviates, vagina cleanness degree (II), vaginal swab is cultivated only has minority bacterial growth, is no more than at most 10;
Invalid: subjective symptoms is without improvement, and vagina cleanness degree is unchanged, vaginal swab is cultivated unchanged.
(5) therapeutic outcome:
Detailed description of the invention
Embodiment 1 one kinds of lipid soluble gynecological gel, are made up of following raw materials by weight portion: Ascorbyl Palmitate 8 parts, Fructus Cnidii 10 parts, Radix Sophorae Flavescentis 7 parts, Borneolum Syntheticum 2 parts, vitamin e 2 parts.
Embodiment 2 one kinds of lipid soluble gynecological gel, are made up of following raw materials by weight portion: Ascorbyl Palmitate 15 parts, Fructus Cnidii 23 parts, Radix Sophorae Flavescentis 17 parts, Borneolum Syntheticum 8 parts, vitamin e 6 parts.
Embodiment 3 one kinds of lipid soluble gynecological gel, are made up of following raw materials by weight portion: Ascorbyl Palmitate 12 parts, Fructus Cnidii 15 parts, Radix Sophorae Flavescentis 12 parts, Borneolum Syntheticum 5 parts, vitamin e 4 parts.
Claims (2)
1. a lipid soluble gynecological gel, is characterized in that: be made up of following raw materials by weight portion:
Ascorbyl Palmitate 8 ~ 15 parts, Fructus Cnidii 10 ~ 23 parts, Radix Sophorae Flavescentis 7 ~ 17 parts, Borneolum Syntheticum 2 ~ 8 parts, vitamin e 2 ~ 6 parts.
2. a kind of lipid soluble gynecological gel as claimed in claim 1, is characterized in that: be made up of following raw materials by weight portion: Ascorbyl Palmitate 12 parts, Fructus Cnidii 15 parts, Radix Sophorae Flavescentis 12 parts, Borneolum Syntheticum 5 parts, vitamin e 4 parts.
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| CN106266863A (en) * | 2016-08-22 | 2017-01-04 | 重庆千贸实业有限公司 | Gynecological gel and preparation method thereof |
| CN106619780A (en) * | 2017-02-24 | 2017-05-10 | 李忠泽 | Gynecological antibacterial gel |
| CN109223892A (en) * | 2018-11-14 | 2019-01-18 | 广西志诚孝善三商贸有限公司 | The gynecological gel of toxin expelling can be sterilized |
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| CN102178794A (en) * | 2011-04-11 | 2011-09-14 | 北京美美源生物科技有限责任公司 | Chinese herbal medicine formula of gynecological gel |
| CN103169921B (en) * | 2013-03-21 | 2015-12-23 | 武汉科磁聚园科技有限公司 | A kind of production method of Zedoary oil microcapsule |
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Effective date of registration: 20190125 Address after: 116620 19-3-2-2 ShuangD4 Street, Dalian Economic and Technological Development Zone, Liaoning Province Patentee after: One bio engineering technology (Dalian) Co., Ltd. Address before: 116620 Unit 19-3, ShuangD Port, ShuangD Fourth Street, Jinzhou New District, Dalian City, Liaoning Province Patentee before: Dalian 5 land 78 bioengineering Co., Ltds |
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