CN103416416A - Sterilizing composition comprising tiadinil - Google Patents
Sterilizing composition comprising tiadinil Download PDFInfo
- Publication number
- CN103416416A CN103416416A CN2012101533697A CN201210153369A CN103416416A CN 103416416 A CN103416416 A CN 103416416A CN 2012101533697 A CN2012101533697 A CN 2012101533697A CN 201210153369 A CN201210153369 A CN 201210153369A CN 103416416 A CN103416416 A CN 103416416A
- Authority
- CN
- China
- Prior art keywords
- tiadinil
- active component
- salt
- bactericidal composition
- weight ratio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VJQYLJSMBWXGDV-UHFFFAOYSA-N tiadinil Chemical compound N1=NSC(C(=O)NC=2C=C(Cl)C(C)=CC=2)=C1C VJQYLJSMBWXGDV-UHFFFAOYSA-N 0.000 title claims abstract description 90
- 239000000203 mixture Substances 0.000 title claims abstract description 46
- 230000001954 sterilising effect Effects 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract description 36
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 31
- 201000010099 disease Diseases 0.000 claims abstract description 30
- WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 claims abstract description 30
- 239000005821 Propamocarb Substances 0.000 claims abstract description 29
- 239000005807 Metalaxyl Substances 0.000 claims abstract description 28
- ZQEIXNIJLIKNTD-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate Chemical compound COCC(=O)N(C(C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-UHFFFAOYSA-N 0.000 claims abstract description 28
- QNBTYORWCCMPQP-JXAWBTAJSA-N (Z)-dimethomorph Chemical compound C1=C(OC)C(OC)=CC=C1C(\C=1C=CC(Cl)=CC=1)=C/C(=O)N1CCOCC1 QNBTYORWCCMPQP-JXAWBTAJSA-N 0.000 claims abstract description 26
- 239000005761 Dimethomorph Substances 0.000 claims abstract description 26
- 239000000375 suspending agent Substances 0.000 claims description 31
- 239000000843 powder Substances 0.000 claims description 30
- 238000009736 wetting Methods 0.000 claims description 30
- 241000233679 Peronosporaceae Species 0.000 claims description 27
- JHXVRRJXCDAINK-UHFFFAOYSA-N NC(=O)N.N#CC#N Chemical compound NC(=O)N.N#CC#N JHXVRRJXCDAINK-UHFFFAOYSA-N 0.000 claims description 25
- 230000000844 anti-bacterial effect Effects 0.000 claims description 19
- 239000003094 microcapsule Substances 0.000 claims description 14
- 235000007164 Oryza sativa Nutrition 0.000 claims description 13
- 235000009566 rice Nutrition 0.000 claims description 13
- 241000221785 Erysiphales Species 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 12
- 241000233614 Phytophthora Species 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 9
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 claims description 8
- 241001530056 Athelia rolfsii Species 0.000 claims description 8
- 241000223218 Fusarium Species 0.000 claims description 8
- 206010027146 Melanoderma Diseases 0.000 claims description 8
- 241000233629 Phytophthora parasitica Species 0.000 claims description 8
- 206010039509 Scab Diseases 0.000 claims description 8
- 230000035613 defoliation Effects 0.000 claims description 8
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 8
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 239000004530 micro-emulsion Substances 0.000 claims description 4
- 208000031968 Cadaver Diseases 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 22
- 230000000694 effects Effects 0.000 abstract description 4
- 150000001875 compounds Chemical class 0.000 abstract description 3
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 abstract description 2
- 239000005756 Cymoxanil Substances 0.000 abstract description 2
- 238000001228 spectrum Methods 0.000 abstract description 2
- 230000003628 erosive effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 50
- 239000003814 drug Substances 0.000 description 48
- 239000002131 composite material Substances 0.000 description 34
- 230000003449 preventive effect Effects 0.000 description 27
- 230000010165 autogamy Effects 0.000 description 21
- 239000000575 pesticide Substances 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- 239000012071 phase Substances 0.000 description 14
- 239000002270 dispersing agent Substances 0.000 description 13
- 241000209094 Oryza Species 0.000 description 12
- 239000013530 defoamer Substances 0.000 description 12
- 240000008067 Cucumis sativus Species 0.000 description 10
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 10
- 239000008367 deionised water Substances 0.000 description 10
- 229910021641 deionized water Inorganic materials 0.000 description 10
- 239000000470 constituent Substances 0.000 description 9
- 239000003995 emulsifying agent Substances 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000002562 thickening agent Substances 0.000 description 9
- 239000000080 wetting agent Substances 0.000 description 9
- 206010067482 No adverse event Diseases 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 238000011835 investigation Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 231100000820 toxicity test Toxicity 0.000 description 8
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 7
- 239000005808 Metalaxyl-M Substances 0.000 description 7
- 240000003768 Solanum lycopersicum Species 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- ZQEIXNIJLIKNTD-GFCCVEGCSA-N metalaxyl-M Chemical compound COCC(=O)N([C@H](C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-GFCCVEGCSA-N 0.000 description 7
- 235000013399 edible fruits Nutrition 0.000 description 6
- 206010011732 Cyst Diseases 0.000 description 5
- 208000031513 cyst Diseases 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 229920002521 macromolecule Polymers 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 239000003381 stabilizer Substances 0.000 description 5
- 239000004094 surface-active agent Substances 0.000 description 5
- 241000220223 Fragaria Species 0.000 description 4
- 235000016623 Fragaria vesca Nutrition 0.000 description 4
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 4
- 241000233622 Phytophthora infestans Species 0.000 description 4
- 241000220317 Rosa Species 0.000 description 4
- 241000209140 Triticum Species 0.000 description 4
- 235000021307 Triticum Nutrition 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 239000003905 agrochemical Substances 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 238000000498 ball milling Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- -1 ethylamino- Chemical class 0.000 description 3
- 230000000855 fungicidal effect Effects 0.000 description 3
- 230000002045 lasting effect Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000192128 Gammaproteobacteria Species 0.000 description 1
- 241000233654 Oomycetes Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- MKIMSXGUTQTKJU-UHFFFAOYSA-N Propamocarb hydrochloride Chemical compound [Cl-].CCCOC(=O)NCCC[NH+](C)C MKIMSXGUTQTKJU-UHFFFAOYSA-N 0.000 description 1
- 241000233639 Pythium Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000003151 ovacidal effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilizing composition comprising tiadinil. The sterilizing composition comprises an active component A and an active component B. The active component A is selected from tiadinil, and the active component B is selected from any one of the following compounds: dimethomorph, metalaxyl and salt thereof, propamocarb and salt thereof, and cymoxanil. A weight ratio of the active component A to the active component B is 1:80-60:1. The composition has relatively high activity against various diseases on various crops, and has a substantial synergetic effect. With the composition, sterilization spectrum is widened, dose is low, rainwater erosion is resisted, and synergetic effect is significant.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest containing tiadinil.
Technical background
Tiadinil (Tiadinil), molecular formula: C
11H
10ClN
3OS, chemical name: 3'-is chloro-4,4'-dimethyl-1,2,3-thiadiazoles-5-formailide, this medicament has well interior absorption, can pass through root absorption, and be transmitted to rapidly other positions, be suitable for the water surface and use, the lasting period is long, and leaf blast disease and fringe rice blast are had to control efficiency preferably.
Dimethomorph (Dimethomorph) chemical name: (E, Z)-4-[3-(4-chlorphenyl) 3-(3,4-Dimethoxyphenyl) acryloyl] morpholine, molecular formula: C
21H
22ClNO
4This product is single-minded ovicidal Gammaproteobacteria fungi bactericide, and its effect characteristics are to destroy the formation of cell envelope, and the stages of oomycetes history of life is had to effect, formation stages at sporangiophore and egg spore is particularly responsive, and under extremely low concentration, (<0.25 μ g/ml) is suppressed.With the phenylamide medicament without cross resistance.
Metalaxyl (Metalaxyl) chemical name: D, L-N-(2,6-3,5-dimethylphenyl)-N-(2'-methoxyl group acetyl) methyl lactamine, molecular formula: C
15H
21NO
4.The salt of metalaxyl refers to Metalaxyl-M (Metalaxyl-M) chemical name: N-(2,6-xylyl)-N-(methoxyl group acetyl group)-D-alanine methyl esters.The systemic fungicide of metalaxyl and the protection of salt tool and therapeutic action; can be absorbed by the root of plant, stem, leaf; and transfer to each organ of plant with moisture content in plant corpus; can make cauline leaf processes; seed treatment and soil treatment are effective to downy mildew, phytophthora, the caused disease of pythium spp.
Propamocarb (Propamocarb) chemical name: 3-(dimethylamino) propyl carbamic acid propyl ester, molecular formula: C
9H
21N
2O
2Cl.The salt of Propamocarb refers to propamocarb (Propamocarb hydrochloride) chemical name: propyl group-3-(dimethylamino) propyl carbamic acid hydrochloride.Propamocarb and salt have local systemic action, also can be used as impregnation process and seed protectant.
Frost urea cyanogen (cymoxanil) chemical name: 2-cyano group-N-[(ethylamino-) carbonyl]-2-(methoxyl group imido grpup) acetamide, molecular formula: C
7H
10N
4O
3.Frost urea cyanogen has contact and local systemic action, can suppress spore germination, effective to downy mildew of garpe, epidemic disease etc., mixed with protective fungicide to extend the lasting period.
Summary of the invention
Tiadinil, metalaxyl and salt, Propamocarb and salt, dimethomorph, the long-term use of white urea cyanogen single dose may bring degradation problem under resistance generation, drug effect, the bactericidal composition that the present invention proposes contains active components A and active component B, and appropriate surfactant and carrier.
A kind of bactericidal composition containing tiadinil, contain active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from tiadinil, and active component B is selected from a kind of in metalaxyl and salt, Propamocarb and salt, dimethomorph, white urea cyanogen.Active components A and active component B preferably weight ratio are 1 ︰ 60 ~ 40 ︰ 1; More preferably the weight ratio of tiadinil and dimethomorph is 1 ︰ 20 ~ 10 ︰ 1, the weight ratio of tiadinil and metalaxyl and salt is 1 ︰ 30 ~ 5 ︰ 1, the weight ratio of tiadinil and Propamocarb and salt is 1 ︰ 35 ~ 5 ︰ 1, and the weight ratio of tiadinil and white urea cyanogen is 1 ︰ 20 ~ 10 ︰ 1.
The disease of the described bactericidal composition containing tiadinil for preventing and treating crops, described crops comprise cereal crops, legume crop, oil crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop.
Described disease comprises black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, gray mold.
Amount of application when in the present composition, the content of active component depends on independent use, also depend on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target disease.Usually in composition, the weight percentage of active component is gross weight 1%～90%, is preferably 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～60% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
At least contain a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water while being beneficial to use.Surface-active contents is 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, thickener or defoamer.According to different dosage form, in preparation, can also contain stabilizing agent known in those skilled in the art, antifreeze etc.
Bactericidal composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by processing method known in those skilled in the art preparation, is about to active component and after liquid flux or solid carrier mix, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
When making wetting powder, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 60%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 1% ~ 80%, active component B 1% ~ 60%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 4%, filler surplus.
Comprise following constituent content when composition is made suspending agent: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0% ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following constituent content when composition is made aqueous emulsion: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, solvent 0 ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0% ~ 2%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
Comprise following constituent content when composition is made microemulsion: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, solvent 0 ~ 30%, emulsifier 3% ~ 20%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, stabilizing agent 0 ~ 4%, deionized water is supplied surplus.
Comprise following constituent content when composition is made microcapsule suspending agent: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, solvent 0 ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content while making microcapsule suspension-suspending agent: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, macromolecule cyst material 2% ~ 12%, surfactant 3% ~ 15%, solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0.05% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Comprise following constituent content when composition is made suspension emulsion: active components A 0.1% ~ 50%, active component B 0.1% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 0 ~ 15%, thickener 0% ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, stabilizing agent 0 ~ 3%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension of the present invention-suspending agent the key technical indexes:
Suspension emulsion the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) the agricultural chemicals dosage reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) enlarged fungicidal spectrum, multiple diseases has been had to greater activity as black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, gray mold.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment all is weight percentage, but the present invention is not limited thereto.
Example 1 ~ 20 wetting powder
Tiadinil, active ingredient B, dispersant, wetting agent, filler are mixed, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, can be made into wetting powder product of the present invention.Specifically in Table 1.
Table 1 example 1 ~ 20 each component and content
Example 21 ~ 33 water dispersible granules
Tiadinil, active ingredient B, dispersant, wetting agent, binding agent, disintegrant, filler are obtained to the particle diameter needed through air-flow crushing together, obtain the materials of granulating.By item quantitatively send in the fluidized bed granulation dryer through granulation and drying after, make water dispersible granules product of the present invention.Specifically in Table 2.
Table 2 example 21 ~ 33 each component and content
Example 34 ~ 45 suspending agents
Dispersant, wetting agent, defoamer, thickener, antifreeze are mixed through high speed shear, add tiadinil, active ingredient B, surplus is supplied by deionized water, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make oil-suspending agent product of the present invention.Specifically in Table 3.
Table 3 example 34 ~ 45 each component and content
Example 46 ~ 50 suspension emulsions
Dispersant, defoamer, thickener, antifreeze, stabilizing agent, solvent in above-mentioned formulation material are mixed through high speed shear, add tiadinil, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make the tiadinil suspending agent, then by active component B, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.Specifically in Table 4.
Table 4 example 46 ~ 50 each component and content
Example 51 ~ 60 aqueous emulsions
Tiadinil, active ingredient B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze, thickener, defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.Specifically in Table 5.
Table 5 example 51 ~ 60 each component and content
Example 61 ~ 64 microcapsule suspending agents
By tiadinil, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, defoamer, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms the macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 6.
Table 6 example 60 ~ 63 each component and content
Example 65,66 microcapsule suspensions-suspending agent
By tiadinil, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener are mixed through high speed shear, add active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, makes the finely disseminated microcapsule suspension of the present composition-suspending agent product.Specifically in Table 7.
Table 7 example 65,66 each component and content
Active component B dimethomorph, Propamocarb and salt, metalaxyl and salt, white urea cyanogen in table 1 ~ 7 are exchanged, can make novel formulation.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect, on this basis, then carry out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and is processed, and establishes the clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament to the crop germ.Measure colony diameter by the right-angled intersection method after 72h, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into to probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50Value.Calculate the different proportioning synergy ratio (SR) of two medicaments according to the Wadley method, SR<0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is tiadinil;
B selects a kind of in dimethomorph, Propamocarb and salt, white urea cyanogen, metalaxyl and salt.
Application Example two:
For trying disease: cucumber downy mildew.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining the former medicine of tiadinil and dimethomorph and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to cucumber downy mildew of table 8 tiadinil and dimethomorph
As shown in Table 8, tiadinil and the dimethomorph proportioning synergy ratio SR to cucumber downy mildew when 1 ︰ 80 ~ 60 ︰ 1 all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of tiadinil and dimethomorph during at 1 ︰ 20 ~ 10 ︰ 1, synergistic effect is more obviously outstanding, and synergy ratio is all more than 2.00.Especially synergy ratio maximum when tiadinil and dimethomorph weight ratio are 1:2, synergistic effect is the most obvious.Testing through the applicant proportioning of finding tiadinil and dimethomorph is 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, during 1:20, tiadinil and dimethomorph are composite to black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, the control of gray mold has obvious synergistic effect, synergy ratio is all more than 1.50.
Application Example three:
For trying disease: tomato late blight.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining tiadinil and metalaxyl and the former medicine of salt and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to tomato late blight of table 9 tiadinil and metalaxyl and salt
As shown in Table 9, tiadinil and metalaxyl and the salt proportioning synergy ratio SR to tomato late blight when 1 ︰ 80 ~ 60 ︰ 1 all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of tiadinil and metalaxyl and salt during at 1 ︰ 25 ~ 5 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Especially synergy ratio maximum when tiadinil and metalaxyl and salt weight ratio are 1:5, synergistic effect is the most obvious.Testing through the applicant proportioning of finding tiadinil and metalaxyl and salt is 5:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:20, during 1:25, tiadinil and metalaxyl and salt are composite to black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, the control of gray mold has obvious synergistic effect, synergy ratio is all more than 1.50.
Application Example four:
For trying disease: cucumber downy mildew.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining tiadinil and Propamocarb and the former medicine of salt and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to cucumber downy mildew of table 10 tiadinil and Propamocarb and salt
As shown in Table 10, tiadinil and Propamocarb and the salt proportioning synergy ratio SR to cucumber downy mildew when 1 ︰ 80 ~ 60 ︰ 1 all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of tiadinil and Propamocarb and salt during at 1 ︰ 30 ~ 5 ︰ 1, synergistic effect is more obviously outstanding, and synergy ratio is all more than 2.20.Especially synergy ratio maximum when tiadinil and Propamocarb and salt weight ratio are 1:6, synergistic effect is the most obvious.Testing through the applicant proportioning of finding tiadinil and Propamocarb and salt is 5:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:20, 1:25, during 1:30, tiadinil and Propamocarb and salt are composite to black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, the control of gray mold has obvious synergistic effect, synergy ratio is all more than 1.50.
Application Example five:
For trying disease: downy mildew of garpe.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining tiadinil and the former medicine of white urea cyanogen and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to downy mildew of garpe of table 11 tiadinil and white urea cyanogen
As shown in Table 11, the proportioning of tiadinil and white urea cyanogen synergy ratio SR to downy mildew of garpe when 1 ︰ 80 ~ 60 ︰ 1 all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of tiadinil and white urea cyanogen during at 1 ︰ 15 ~ 10 ︰ 1, synergistic effect is more obviously outstanding, and synergy ratio is all more than 2.10.Especially synergy ratio maximum when tiadinil and white urea cyanogen weight ratio are 2:3, synergistic effect is the most obvious.Testing through the applicant proportioning of finding tiadinil and white urea cyanogen is 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, during 1:15, tiadinil and white urea cyanogen are composite to black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, the control of gray mold has obvious synergistic effect, synergy ratio is all more than 1.50.
Application Example six tiadinils and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in the Xianyang, Shanxi province city; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation downy mildew of garpe state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 12 tiadinil and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 12, after tiadinil and active component B are composite, can effectively prevent and treat downy mildew of garpe, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven tiadinils and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is at the Xi'an City, Shanxi Province Changan District; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 20% Metalaxyl-M missible oil (autogamy), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation cucumber downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 13 tiadinil and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 13, after tiadinil and active component B are composite, can effectively prevent and treat cucumber downy mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight tiadinils and active component B and the composite control tomato blight test of pesticide effectiveness thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 20% Metalaxyl-M missible oil (autogamy), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation tomato blight state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 14 tiadinil and active component B and the composite control tomato blight test of pesticide effectiveness thereof
As can be seen from Table 14, after tiadinil and active component B are composite, can effectively prevent and treat tomato blight, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine tiadinils and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation rice blast state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 15 tiadinil and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 15, after tiadinil and active component B are composite, can effectively prevent and treat rice blast, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten tiadinils and active component B and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in the Jingyang County, Shaanxi Province; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 20% Metalaxyl-M missible oil (autogamy), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation potato late blight state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 16 tiadinil and active component B and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 16, after tiadinil and active component B are composite, can effectively prevent and treat potato late blight, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 11 tiadinils and active component B and the composite control grey mould fruit rot of strawberry test of pesticide effectiveness thereof
This test arrangement is in Weinan City suburb, Shaanxi Province; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation grey mould fruit rot of strawberry state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 17 tiadinil and active component B and the composite control grey mould fruit rot of strawberry test of pesticide effectiveness thereof
As can be seen from Table 17, after tiadinil and active component B are composite, can effectively prevent and treat grey mould fruit rot of strawberry, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 12 tiadinils and active component B and the composite control wheat leaf blight test of pesticide effectiveness thereof
This test arrangement is at the Xian District, Shanxi Province suburban area; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (commercial), 20% Metalaxyl-M missible oil (autogamy), 35% Propamocarb aqua (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation wheat leaf blight state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 18 tiadinil and active component B and the composite control wheat leaf blight test of pesticide effectiveness thereof
As can be seen from Table 18, after tiadinil and active component B are composite, can effectively prevent and treat wheat leaf blight, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 13 tiadinils and active component B and the composite control rose powdery mildew test of pesticide effectiveness thereof
This test arrangement is at the Jinan City, Shandong Province Pingying County; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 24% tiadinil suspending agent (autogamy), 25% metalaxyl wetting powder (commercial), 35% Propamocarb aqua (commercial), 20% Metalaxyl-M missible oil (autogamy), 50% dimethomorph wetting powder (commercial), 20% white urea cyanogen wetting powder (autogamy).
The investigation rose powdery mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after dispenser 7 days, 14 days, 30 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 19 tiadinil and active component B and the composite control rose powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 19, after tiadinil and active component B are composite, can effectively prevent and treat the rose powdery mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After through different local throughout the country tests, draw, tiadinil and dimethomorph, metalaxyl and salt, Propamocarb and salt, the composite rear preventive effect to Common Diseases such as the black spot on various crop, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, gray molds of white urea cyanogen are all more than 95%, be better than the single dose preventive effect, synergistic effect is obvious.
Claims (9)
1. the bactericidal composition containing tiadinil, it is characterized in that containing active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from tiadinil, and active component B is selected from a kind of in dimethomorph, metalaxyl and salt, Propamocarb and salt, white urea cyanogen.
2. the bactericidal composition containing tiadinil according to claim 1, it is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition containing tiadinil according to claim 2, it is characterized in that: the weight ratio of tiadinil and dimethomorph is 1 ︰ 20 ~ 10 ︰ 1.
4. the bactericidal composition containing tiadinil according to claim 2, it is characterized in that: the weight ratio of tiadinil and metalaxyl and salt is 1 ︰ 25 ~ 5 ︰ 1.
5. the bactericidal composition containing tiadinil according to claim 2, it is characterized in that: the weight ratio of tiadinil and Propamocarb and salt is 1 ︰ 30 ~ 5 ︰ 1.
6. the bactericidal composition containing tiadinil according to claim 2, it is characterized in that: the weight ratio of tiadinil and white urea cyanogen is 1 ︰ 15 ~ 10 ︰ 1.
7. contain the bactericidal composition of tiadinil according to the described any one of claim 3 to 6, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
8. the bactericidal composition containing tiadinil according to claim 7, for preventing and treating the application of corps diseases.
9. application according to claim 8 is characterized in that: described disease comprises black spot, epidemic disease, powdery mildew, downy mildew, anthracnose, banded sclerotial blight, fusarium wilt, rust, phytophthora root rot, brown spot, leaf blight, late blight, balck shank, damping off, scab, spot defoliation, rice blast, gray mold.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210153369.7A CN103416416B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
| CN201610087466.9A CN105613520B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210153369.7A CN103416416B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610087466.9A Division CN105613520B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103416416A true CN103416416A (en) | 2013-12-04 |
| CN103416416B CN103416416B (en) | 2016-05-18 |
Family
ID=49642223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210153369.7A Expired - Fee Related CN103416416B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
| CN201610087466.9A Expired - Fee Related CN105613520B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610087466.9A Expired - Fee Related CN105613520B (en) | 2012-05-17 | 2012-05-17 | A kind of bactericidal composition containing tiadinil |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN103416416B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109769843A (en) * | 2019-03-11 | 2019-05-21 | 西华大学 | A kind of bactericidal composition containing metalaxyl, pesticide and application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642130A (en) * | 2009-09-08 | 2010-02-10 | 深圳诺普信农化股份有限公司 | Bactericidal composition containing iprovalicarb |
| CN101647446A (en) * | 2009-06-22 | 2010-02-17 | 陕西标正作物科学有限公司 | Bactericidal composite with fluopicolide and dimethomorph |
| CN102057928A (en) * | 2010-12-31 | 2011-05-18 | 河北省农林科学院植物保护研究所 | Composite bactericide for controlling fruit and vegetable oomycetes diseases |
| CN102316729A (en) * | 2009-02-11 | 2012-01-11 | 巴斯夫欧洲公司 | Dimethomorph as safener for pesticides with phytotoxic effects |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0976326B1 (en) * | 1998-07-30 | 2003-05-02 | Nihon Nohyaku Co., Ltd. | Fungicidal composition containing a 1,2,3-tiadiazole derivative and its use |
| WO2010139653A1 (en) * | 2009-06-04 | 2010-12-09 | Basf Se | Fungicidal mixtures comprising heteraromatic sulfonamides |
-
2012
- 2012-05-17 CN CN201210153369.7A patent/CN103416416B/en not_active Expired - Fee Related
- 2012-05-17 CN CN201610087466.9A patent/CN105613520B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102316729A (en) * | 2009-02-11 | 2012-01-11 | 巴斯夫欧洲公司 | Dimethomorph as safener for pesticides with phytotoxic effects |
| CN101647446A (en) * | 2009-06-22 | 2010-02-17 | 陕西标正作物科学有限公司 | Bactericidal composite with fluopicolide and dimethomorph |
| CN101642130A (en) * | 2009-09-08 | 2010-02-10 | 深圳诺普信农化股份有限公司 | Bactericidal composition containing iprovalicarb |
| CN102057928A (en) * | 2010-12-31 | 2011-05-18 | 河北省农林科学院植物保护研究所 | Composite bactericide for controlling fruit and vegetable oomycetes diseases |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109769843A (en) * | 2019-03-11 | 2019-05-21 | 西华大学 | A kind of bactericidal composition containing metalaxyl, pesticide and application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103416416B (en) | 2016-05-18 |
| CN105613520B (en) | 2018-02-06 |
| CN105613520A (en) | 2016-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104719297A (en) | Sterilization composition containing sedaxane and methoxy acrylate | |
| CN103518770B (en) | Bactericidal composition containing fluopyram and triazole | |
| CN105145584A (en) | Sterilization composition containing penthiopyrad | |
| CN103416428A (en) | Fluxapyroxad-containing sterilization composition | |
| CN103651538B (en) | A kind of bactericidal composition containing zoxamide | |
| CN103416410A (en) | Fluxapyroxad-containing sterilization composition | |
| CN103563971A (en) | Bactericidal composition containing simeconazole and methoxy acrylate | |
| CN103416416B (en) | A kind of bactericidal composition containing tiadinil | |
| CN104285954A (en) | Efficient fungicidal composition | |
| CN103535365A (en) | Bactericidal composition | |
| CN103478152B (en) | Fenamidone-containing sterilization composition | |
| CN103621550B (en) | Chesulfamide-containing pesticide composition | |
| CN103416427B (en) | A kind of bactericidal composition containing tiadinil | |
| CN103371189A (en) | Bactericidal composition containing agricultural antibiotic | |
| CN103583560B (en) | A kind of bactericidal composition containing simeconazoles and thiocarbamates | |
| CN103651450B (en) | Bactericidal composition containing dimoxystrobin and thiocarbamate | |
| CN105284806A (en) | Sterilization composition containing zoxamide and strobilurin | |
| CN105724386B (en) | A kind of bactericidal composition of Fluxapyroxad-containsterilization | |
| CN103444744A (en) | Sterilization composition containing fenamidone and strobilurin | |
| CN105638686B (en) | A kind of combination sterilization composition containing tiger glue adipic acid copper | |
| CN103371187A (en) | Bactericidal composition containing agricultural antibiotic | |
| CN105340932A (en) | Bactericidal composition containing fluopyram | |
| CN103416417B (en) | The fungicidal composition of a kind of fluorine-containing azoles bacterium acid amides | |
| CN103371185A (en) | Synergistic antibacterial composition containing pyrimidine nucleoside antibiotics | |
| CN103461338A (en) | Bactericidal composition comprising fenamidone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee after: Shaanxi yitianfeng crop Technology Co.,Ltd. Address before: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee before: Shaanxi Welch Crop Protection Co.,Ltd. |
|
| CP01 | Change in the name or title of a patent holder | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160518 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |