CN103385975B - Traditional Chinese medicine for treating thrombocytopenia - Google Patents
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Abstract
一种治疗血小板低下的中药药物,其特征是一个疗程的药物由下列药物原料制成:金银花炭50-100克,荆芥炭50-100克,黄芪150-300克,党参150-300克,白术50-100克,大枣100-200克,生地黄150-300克,地骨皮100-200克,白芍100-200克,枸杞子100-200克。本发明本着标本同治,营卫互补,气血共养,从而得到血小板再生性生长,给于生理正常,血小板同步恢复正常。本发明通过肝脾肾去完成血液再生功能。A traditional Chinese medicine for treating low platelets, characterized in that a course of medicine is made of the following medicinal materials: 50-100 grams of honeysuckle charcoal, 50-100 grams of nepeta charcoal, 150-300 grams of astragalus, 150-300 grams of Codonopsis pilosula, 50-100 grams of Atractylodes macrocephala, 100-200 grams of jujube, 150-300 grams of raw rehmannia, 100-200 grams of Digupi, 100-200 grams of white peony, and 100-200 grams of medlar. The present invention treats both the symptoms and root causes, complements nutrition and health, and nourishes qi and blood together, so as to obtain platelet regenerative growth, give physiologically normal, and platelet synchronously return to normal. The present invention completes the blood regeneration function through the liver, spleen and kidney.
Description
一、技术领域1. Technical field
本发明涉及一种治疗血小板低下的的药物。The invention relates to a medicine for treating low platelets.
二、背景技术2. Background technology
血小板(blood platelet)是哺乳动物血液中的有形成分之一。形状不规则,比红细胞和白细胞小得多,无细胞核,成年人血液中血小板数量为(1-3)×100×109/L,它有质膜,没有细胞核结构,一般呈圆形,体积小于红细胞和白细胞。血小板具有特定的形态结构和生化组成,在正常血液中有较恒定的数量(如人的血小板数为每立方毫米10~30万),在止血、伤口愈合、炎症反应、血栓形成及器官移植排斥等生理和病理过程中有重要作用。血小板的主要功能是凝血和止血,修补破损的血管。当血小板计数<100×1109/L即为血小板减少,常见于血小板生成障碍,如再生障碍性贫血,急性白血病,急性放射病等;血小板破坏增多,如原发性血小板减少性紫癜,脾功能亢进,消耗过度如弥漫性血管内凝血,家族性血小板减少如巨大血小板综合征等。很多医学工作者为此研究付出了毕生精力,研制了多种药物,但大多疗效并不显著。Platelet (blood platelet) is one of the formed components in mammalian blood. Irregular in shape, much smaller than red blood cells and white blood cells, no nucleus, the number of platelets in adult blood is (1-3)×100×10 9 /L, it has a plasma membrane, no nucleus structure, generally round, volume smaller than red and white blood cells. Platelets have a specific morphological structure and biochemical composition, and have a relatively constant number in normal blood (for example, the number of human platelets is 100,000 to 300,000 per cubic millimeter). important roles in physiological and pathological processes. The main function of platelets is to coagulate and stop bleeding, and to repair damaged blood vessels. When the platelet count is <100×110 9 /L, it is thrombocytopenia, which is common in thrombocytopenia, such as aplastic anemia, acute leukemia, acute radiation sickness, etc.; increased platelet destruction, such as idiopathic thrombocytopenic purpura, hypersplenism , Excessive consumption such as disseminated intravascular coagulation, familial thrombocytopenia such as giant platelet syndrome, etc. Many medical workers have devoted their whole lives to this research and developed a variety of drugs, but most of them have insignificant curative effects.
常见血小板减少症处方有:Common thrombocytopenia prescriptions include:
中药处方(一):犀角3克,生地30克,丹皮10克,赤芍10克,白薇10克,紫草10克,知母10克,沙参10克,生槐花30克,大青叶10克,板蓝根15克。Chinese medicine prescription (1): 3 grams of rhino horn, 30 grams of raw land, 10 grams of paeonol, 10 grams of red peony, 10 grams of Baiwei, 10 grams of comfrey, 10 grams of Anemarrhena, 10 grams of Radix Ginseng, 30 grams of raw Sophora japonica, Daqingye 10 grams, Banlangen 15 grams.
中药处方(二):生地10克,生白芍30克,旱莲草15克,山药20克,莲米15克,连翘10克,赤小豆30克,黄连6克,淡竹叶10克,五味子10克,枣皮10克,大枣10个,炙甘草10克。Chinese medicine prescription (2): 10 grams of raw land, 30 grams of raw white peony, 15 grams of eclipta, 20 grams of yam, 15 grams of lotus rice, 10 grams of forsythia, 30 grams of red bean, 6 grams of berberine, 10 grams of light bamboo leaves, schisandra 10 grams, 10 grams of jujube skin, 10 jujubes, 10 grams of roasted licorice.
中药处方(三):鸡血藤15克,丹皮15克,茜草15克,当归15克,大枣10克,茅根15克,旱莲草20克,三七粉5克(冲服),仙鹤草20克,山栀15克。此外:Traditional Chinese medicine prescription (3): 15 grams of Caulis Spatholobus, 15 grams of paeonol, 15 grams of madder, 15 grams of angelica, 10 grams of jujube, 15 grams of grass root, 20 grams of Eclipta, 5 grams of Panax notoginseng powder (mixed), crane 20 grams of grass, 15 grams of shanzhi. also:
申请号CN201310017355的专利申请公开了一种升血小板中药组合物及其制备方法,该中药组合物是由青黛、连翘、仙鹤草、牡丹皮、甘草共五味中药制备而成;该药具有清热解毒,凉血止血,散瘀消斑的功效;主要用于原发性血小板减少性紫癜;症见:全身瘀点或瘀斑,发热烦渴,小便短赤,大便秘结,或见鼻衄,齿衄,舌红苔黄,脉滑数或弦数。The patent application with application number CN201310017355 discloses a traditional Chinese medicine composition for increasing blood platelets and a preparation method thereof. , the effect of cooling blood to stop bleeding, dissipating blood stasis and eliminating spots; mainly used for idiopathic thrombocytopenic purpura; symptoms: petechiae or ecchymosis all over the body, fever and polydipsia, short red urine, constipation, or epistaxis, Teeth bleeding, red tongue with yellow coating, slippery or stringy pulse.
申请号CN201210570569的专利申请公开了一种治疗血小板减少症的药物组合物,该组合物是由人参,淫羊藿,黄芪,当归,熟地,鸡血藤,仙鹤草及陈皮组成。The patent application with the application number CN201210570569 discloses a pharmaceutical composition for treating thrombocytopenia, which is composed of ginseng, epimedium, astragalus, angelica, rehmannia glutinosa, spaghetti vine, agrimony and tangerine peel.
申请号CN201210483181的专利申请公开了治疗血液病原发性血小板减少性紫癜的药物,该发明药物是由下列组分制成的:木蝴蝶30克,黄芩50克,黄柏75克,龙胆草40克,大青叶75克,板蓝根50克,射干60克,黄连75克,半枝莲200克,半边莲150克,石见穿60克,山慈菇50克;将上述各组分混合均匀粉碎成150目细粉,分装成袋,每袋装药粉6克。饭后服用。The patent application with the application number CN201210483181 discloses the medicine for the treatment of blood disease idiopathic thrombocytopenic purpura. 75 grams of Daqingye, 50 grams of Radix Isatidis, 60 grams of Shegan, 75 grams of Coptis chinensis, 200 grams of Banzhilian, 150 grams of Lobelia, 60 grams of Shijianchuan, 50 grams of Shanzi mushroom; mix the above components evenly Crushed into 150 mesh fine powder, divided into bags, 6 grams of powder in each bag. Take after meals.
三、发明内容3. Contents of the invention
本发明的目的是克服现有技术的不足,研制一种疗效显著的治疗血小板低下的中药药物。The purpose of the invention is to overcome the deficiencies in the prior art, and develop a Chinese medicinal drug for treating thrombocytopenia with remarkable curative effect.
本发明的组方和剂量为:Prescription and dosage of the present invention are:
一种治疗血小板低下的中药药物,其特征是一个疗程的药物由下列药物原料制成:A traditional Chinese medicine for treating low platelets, characterized in that a course of medicine is made of the following raw materials:
金银花炭50-100克,荆芥炭50-100克,黄芪150-300克,党参150-300克,白术50-100克,大枣100-200克,生地黄150-300克,地骨皮100-200克,白芍100-200克,枸杞子100-200克。Honeysuckle Charcoal 50-100g, Nepeta charcoal 50-100g, Astragalus 150-300g, Codonopsis 150-300g, Atractylodes macrocephala 50-100g, Jujube 100-200g, Rehmannia glutinosa 150-300g, Digupi 100-200 grams, 100-200 grams of white peony, 100-200 grams of wolfberry.
上述药物可以采用中药制备的常规方法制成丸、片剂、或胶囊吞服,每天服用三次,成人每次6克,儿童减半;也可以采用常规的煎服方式。大多数患者服用一个疗程的药物就能痊愈,重症患者二到三个疗程的药物也能痊愈。The above-mentioned medicines can be made into pills, tablets, or capsules by the conventional method of traditional Chinese medicine preparation, and swallowed, and take three times a day, 6 grams each time for adults, and half for children; conventional decoction can also be used. Most patients can recover after taking one course of medicine, and severe patients can also recover after taking two to three courses of medicine.
药性及功能:金银花,甘寒入肺心,清热解毒,疏散风热,炭直入营卫,散风止血;荆芥,辛微温,归肺、肝,发表散风,炭去辛,入营血去风止血;黄芪甘、微温,归脾肺,补气固表;党参甘平,归脾肺,补中气而养血;白术甘、苦、温、归脾胃经,补气健脾,燥湿利尿;大枣甘温,归脾胃,补中气养脾和胃;生地黄,甘、苦、寒,归心肝,肾经,清热凉血,养阴生津;地骨皮,甘、淡、寒、归肺、肾经、凉血退蒸,清洗肺热;白芍甘寒而酸,归肝脾,养血护肝,藏血,酸收止血;枸杞子,甘平、归肝、肾、肺经,补肾益精,养肝明目兼润肺。Medicinal properties and functions: honeysuckle, sweet and cold enter the lungs and heart, clear away heat and detoxify, evacuate wind-heat, charcoal enters the camp directly, disperses wind to stop bleeding; Eliminate wind and stop bleeding; Astragalus is sweet and slightly warm, returns to the spleen and lungs, invigorates qi and strengthens the surface; Codonopsis sweet and flat, returns to the spleen and lungs, invigorates middle qi and nourishes blood; Dampness and diuresis; Jujube is sweet and warm, returns to the spleen and stomach, invigorates the Qi and nourishes the spleen and stomach; Raw Rehmannia, sweet, bitter, and cold, returns to the heart and liver, kidney meridian, clears heat and cools blood, nourishes yin and promotes body fluid; Digupi, sweet, light, Cold, return to lung, kidney meridian, cool blood, relieve steam, cleanse lung heat; white peony root is sweet and sour, return to liver and spleen, nourish blood and protect liver, store blood, absorb acid to stop bleeding; wolfberry, Ganping, return to liver and kidney , lung meridian, nourishing kidney and essence, nourishing liver, improving eyesight and moistening lung.
本发明本着标本同治,营卫互补,气血共养,从而使血小板再生性生长,给于生理正常,血小板同步恢复正常。解决了医患血供难的难题,这样既减轻政府动员献血人员的压力,又减少患者的经济负担,医师也不用供血不足而着急。The present invention treats both the symptoms and the root causes, complements nutrition and health, and nourishes qi and blood together, so that the platelets can regenerate and grow, giving them normal physiology, and the platelets can be restored to normal synchronously. It solves the problem of difficult blood supply for doctors and patients, which not only reduces the pressure on the government to mobilize blood donors, but also reduces the financial burden of patients, and doctors do not have to worry about insufficient blood supply.
本发明通过肝脾肾去完成血液再生功能。The present invention completes the blood regeneration function through the liver, spleen and kidney.
上述方剂的剂量,是经过多次试验、临床应用定下来的安全有效的剂量,超过上限可能会产生一定的毒副作用,低于下限效果不明显。可根据不同类型的血小板低下症状组方遣药配伍、相需为用。The dosage of the above-mentioned prescription is a safe and effective dosage determined through many tests and clinical applications. If it exceeds the upper limit, certain toxic and side effects may occur, and if it is lower than the lower limit, the effect will not be obvious. According to different types of thrombocytopenia symptoms, prescriptions can be dispatched for compatibility and use as needed.
四、具体实施方式4. Specific implementation
下面给出本发明根据患者病情轻重程度不同的6个处方实施例(下表中单位均为质量g):Provide below the present invention according to 6 different prescription embodiments of patient's degree of illness severity (unit is quality g in the following table):
典型病例说明如下:A typical case description is as follows:
例一:绵阳市某院女职工,28岁,血小板低下,全身皮下出血,皮肤全成黑色,舌体黑色,双眼球充血,内脏出血,吐血疴血严重,病人无力支撑,在几大医院视为难治危症,经人介绍到发明人处,经发明人诊断后给开了本发明汤药回家去煎服,到第三天皮肤颜色变过来了,舌不黑了,眼球的血也退了,又不吐血疴血了,吃饭也好了,精神也好了。发明人再开一个疗程本发明丸药服用后,去医院复查,报告结果,完全恢复正常。Example 1: A 28-year-old female worker in a hospital in Mianyang City, with low platelets, subcutaneous hemorrhage all over the body, black skin, black tongue, hyperemia in both eyes, internal bleeding, severe hematemesis, and the patient was unable to support herself. For the intractable critical disease, I was introduced to the inventor, and after the inventor's diagnosis, I prescribed the decoction of the present invention and went home to decoct it. On the third day, the skin color changed, the tongue was no longer black, and the blood in the eyeballs also disappeared. Now, I don't vomit blood anymore, I can eat better, and my energy is better. The inventor opens a course for the treatment of again after the pill of the present invention is taken, goes to the hospital for reexamination, reports the result, returns to normal fully.
例二:秦某某,女,43岁,绵阳游仙区人,因血小板低下,口腔出血、牙出血,治疗几年未愈。经人介绍来发明人处求医,用本发明丸药服用一个疗程全好了,去医院复查一切正常。Example 2: Qin Moumou, female, 43 years old, from Youxian District, Mianyang, suffered from low platelets, oral bleeding, and dental bleeding, which did not heal after several years of treatment. Come to seek medical advice at the inventor's place through people's introduction, take a course for the treatment of with pill of the present invention and all is well, go to the hospital to check and everything is normal.
例三:绵阳经开区板桥社区一小男孩,2岁多一点,因血小板低下,住院治疗半年多,结果血小板几乎到零了。孩子满脸是血,全身各处都是紫斑,一个大头大脸的激素体质,全身情况不太好。经发明人诊断后,按儿童剂量每次3克每日3次本发明丸药服用一个疗程(一个半月),去医院复查,报告结果证明一切恢复正常。Example 3: A boy in Banqiao Community, Economic Development Zone, Mianyang, a little over 2 years old, was hospitalized for more than half a year because of low platelets, and his platelets almost reached zero. The child's face is covered with blood, and there are purple spots all over his body. He has a big head and a big face, and he has a hormonal physique. His whole body is not in good condition. After the inventor's diagnosis, take a course of treatment (one and a half months) by each 3 grams of pills of the present invention every day 3 times by children's dosage, go to the hospital for check-up, and the report result proves that everything returns to normal.
十多年来经发明人用该药物治疗的血小板低下患者数百人次,没有不愈的。Hundreds of patients with low platelets have been treated with this drug by the inventor for more than ten years, and there is no unhealed one.
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