CN103271406B

CN103271406B - Compound amphiphilic core microcapsule electuary and preparation method thereof

Info

Publication number: CN103271406B
Application number: CN201310228666.8A
Authority: CN
Inventors: 刘静波; 刘丹; 周玉权; 张燕; 马爽
Original assignee: Jilin University
Current assignee: Jilin University
Priority date: 2013-06-08
Filing date: 2013-06-08
Publication date: 2014-07-16
Anticipated expiration: 2033-06-08
Also published as: CN103271406A

Abstract

一种复合型两亲性芯材微胶囊冲剂及其制备方法，属于农副产品精深加工及其副产物综合利用的技术领域。微胶囊冲剂由β-环糊精、小肽、单糖和水溶性维生素、卵磷脂和脂溶性维生素组成，以质量和100%计算，β-环糊精的质量含量为55～65%，小肽、单糖、水溶性维生素的质量相同，质量含量为5～8%，卵磷脂和脂溶性维生素的质量相同，质量含量为7.5～12%，乳化剂的质量含量为0.25～0.6%。本发明微胶囊冲剂是含有多种营养素的保健品，且货架期长，便于加工，贮藏和运输。A composite amphiphilic core material microcapsule granule and a preparation method thereof belong to the technical field of deep processing of agricultural by-products and comprehensive utilization of by-products. Microcapsule granules are composed of β-cyclodextrin, small peptides, monosaccharides, water-soluble vitamins, lecithin and fat-soluble vitamins. Calculated by mass and 100%, the mass content of β-cyclodextrin is 55-65%. Peptides, monosaccharides, and water-soluble vitamins have the same mass content of 5-8%, lecithin and fat-soluble vitamins have the same mass content of 7.5-12%, and emulsifiers have a mass content of 0.25-0.6%. The microcapsule granule of the invention is a health care product containing multiple nutrients, has a long shelf life, and is convenient for processing, storage and transportation.

Description

A kind of compound amphipathic core micro-capsule granules and preparation method thereof

Technical field

The invention belongs to agricultural byproducts intensive processing and byproduct comprehensive thereof and utilize technical field, be specifically related to a kind of compound amphipathic core micro-capsule granules and preparation method thereof.

Background technology

Along with the quickening of people's rhythm of life, the transformation of growth in the living standard and philosophy of life, the requirement that people take in foodstuff nutriment is comprehensively more and more higher, and the parent that the food with natural, convenient, delicious food and multifunctional characteristics is more and more subject to people looks at.Peptide class, lecithin, vitamin etc. are the function factors of needed by human, have good nutrition health-care functions, but these function factors are but very easily oxidized and rotten, lose its function.This just need to find a kind of stable technique for packing, and its function is protected.

Microcapsules technology refers to the solid matter, drop or the gas that disperse is encapsulated in to the method that forms microcapsules in one deck dense film completely.Conventionally dense film is to be made up of natural or artificial synthetic macromolecular material.Microcapsules technology has been applied in the industry such as medicine, agricultural, computer, chemicals, food, cosmetics, has caused the extensive concern of academia.

Summary of the invention

The object of this invention is to provide a kind of compound amphipathic core micro-capsule granules and preparation method thereof, the micro-capsule granules obtaining is made up of beta-schardinger dextrin-, little peptide, monose, water soluble vitamin, lecithin and liposoluble vitamin, calculate with quality and 100%, the mass content of beta-schardinger dextrin-is 55～65%, little peptide, monose and water soluble vitamin identical in quality, mass content is 5～8%, lecithin and liposoluble vitamin identical in quality, mass content is 7.5～12%, and the mass content of emulsifying agent is 0.25～0.6%.

The preparation method of a kind of compound amphipathic core micro-capsule granules of the present invention, its step is as follows:

(1) will after the mass ratio mixing such as little peptide, monose and water soluble vitamin, in water, dissolve, the gross mass mark of little peptide, monose and water soluble vitamin is 1%～5%;

(2) by dissolving in water after the mixing of the mass ratio such as lecithin and liposoluble vitamin, also magnetic agitation is even, the gross mass mark of lecithin and liposoluble vitamin is 1%～5%, then add emulsifying agent, emulsifying agent is sucrose fatty ester, every 100g lecithin adds emulsifying agent 3～5g, obtains stable emulsion after high-pressure homogeneous 2～8min;

(3) emulsion that solution step (1) being obtained and step (2) obtain is even by volume ratio mixing the magnetic agitation of 1:0.5～3, makes mixed liquor;

(4) beta-schardinger dextrin-is dissolved in the hot water of 40～80 DEG C, it is in 2%～10% beta-schardinger dextrin-solution that the mixed liquor stirring while step (3) is obtained joins mass fraction, the volume ratio of its mixed liquor and beta-schardinger dextrin-solution is 1:1～3, continue high-pressure homogeneous 3～5min, then ultrasonic 40～80min, ultrasonic power is 300～500W, ultrasonic temperature is 40～80 DEG C, last suction filtration, vacuum freeze drying, through collecting the finished product that obtains compound amphipathic micro-capsule granules of the present invention after dressing sieve selects.

Wherein, described little peptide can be Soybean Peptide, egg white peptide, corn peptide etc.; Described monose can be glucose, fructose etc., and described water soluble vitamin can be ascorbic acid (vitamin C), thiamines (vitamin B1), riboflavin (vitamin B2), nicotinic acid (vitamin B3) etc.

Described lecithin can be egg yolk lecithin, soybean lecithin etc., and described liposoluble vitamin can be retinol (vitamin A), tocopherol (vitamin E) etc.

Described suction filtration is low speed Filter paper filtering in adopting, and collects and obtains filter cake.

Described vacuum freeze drying be filter cake is less than in vacuum under the condition of 10Pa, cold sunken temperature-45～30 DEG C dry totally.

Detailed description of the invention

Embodiment 1:

1g Soybean Peptide, 1g glucose, 1g vitamin C are dissolved in 100ml water, obtain solution for standby; 1.5g egg yolk lecithin, 1.5g tocopherol are mixed and magnetic agitation in 100ml water, add the sucrose fatty ester of 0.075g, homogeneous 5min under high pressure homogenizer, obtains stable emulsion for subsequent use; The solution that above-mentioned steps is obtained and emulsion are even according to volume ratio mixing and the magnetic agitation of 1:1, make mixed liquor for subsequent use; 10g beta-schardinger dextrin-in being the hot water of 60 DEG C, 200mL and temperature is dissolved, stir while 200mL mixed liquor obtained above is joined in the 200mL beta-schardinger dextrin-solution obtaining, continue high-pressure homogeneous 3min, transfer to ultrasonic 60min in ultrasonic device, ultrasonic power 500W, temperature 50 C, and then suction filtration, the filter cake that suction filtration is obtained is 5Pa in vacuum, under the condition of cold sunken temperature-45～30 DEG C, freeze drying totally, obtain the powder of microcapsules, after the choosing of collection dressing sieve, obtain even-grained electuary, quality is 12.86g.

The micro-capsule granules finished product feel exquisiteness obtaining, uniform particles, and embedding rate reaches more than 80%, and shelf life is long, is convenient to storage.

Embodiment 2:

2g corn peptide, 2g fructose, 2g dissolution of ascorbic acid, in 150ml water, are obtained to solution for standby; 3g egg yolk lecithin, 3g retinol are mixed and magnetic agitation in 150ml water, add the sucrose fatty ester of 0.125g, homogeneous 5min under high pressure homogenizer, obtains stable emulsion for subsequent use; The solution that above-mentioned steps is obtained and emulsion are even according to volume ratio mixing and the magnetic agitation of 1:1, make mixed liquor for subsequent use; 15g beta-schardinger dextrin-in being the hot water of 60 DEG C, 400mL and temperature is dissolved, stir while 300mL mixed liquor obtained above is joined in the 400mL beta-schardinger dextrin-solution obtaining, continue high-pressure homogeneous 3min, transfer to ultrasonic 60min in ultrasonic device, ultrasonic power 500W, temperature 50 C, and then suction filtration, the filter cake that suction filtration is obtained is 5Pa in vacuum, under the condition of cold sunken temperature-45～30 DEG C, freeze drying totally, obtain the powder of microcapsules, after the choosing of collection dressing sieve, obtain even-grained electuary, quality is 21.7g.

Embodiment 3:

1.5g egg white peptide, 1.5g glucose, 1.5g riboflavin are dissolved in 100ml water, obtain solution for standby; 2.25g soybean lecithin, 2.25g tocopherol are mixed and magnetic agitation in 120ml water, add the sucrose fatty ester of 0.11g, homogeneous 5min under high pressure homogenizer, obtains stable emulsion for subsequent use; The solution that above-mentioned steps is obtained and emulsion are even according to volume ratio mixing and the magnetic agitation of 1:1.2, make mixed liquor for subsequent use; 12g beta-schardinger dextrin-in being the hot water of 60 DEG C, 300mL and temperature is dissolved, stir while 220mL mixed liquor obtained above is joined in the 300mL beta-schardinger dextrin-solution obtaining, continue high-pressure homogeneous 3min, transfer to ultrasonic 60min in ultrasonic device, ultrasonic power 400W, temperature 60 C, and then suction filtration, the filter cake that suction filtration is obtained is 5Pa in vacuum, under the condition of cold sunken temperature-45～30 DEG C, freeze drying totally, obtain the powder of microcapsules, after the choosing of collection dressing sieve, obtain even-grained electuary, quality is 16.88g.

Claims

1. A composite type amphiphilic core material microcapsule granule, characterized in that: the microcapsule granule is made up of β-cyclodextrin, small peptide, monosaccharide, water-soluble vitamin, lecithin and fat-soluble vitamin, with quality Calculated with 100%, the mass content of β-cyclodextrin is 55-65%; the mass content of small peptides, monosaccharides and water-soluble vitamins is the same, and the mass content is 5-8%; the mass content of lecithin and fat-soluble vitamins is the same, The mass content is 7.5-12%; the mass content of the emulsifier is 0.25-0.6%; and the microcapsule granule is prepared by the following steps,

(1) Mix small peptides, monosaccharides and water-soluble vitamins in equal mass ratios and dissolve them in water. The total mass fraction of small peptides, monosaccharides and water-soluble vitamins is 1% to 5%;

(2) Mix lecithin and fat-soluble vitamins in equal mass ratios, dissolve in water and stir evenly with a magnetic force. The total mass fraction of lecithin and fat-soluble vitamins is 1% to 5%, and then add an emulsifier, which is sucrose fat Ester, add 3-5g of emulsifier per 100g of lecithin, and obtain a stable emulsion after high-pressure homogenization for 2-8 minutes;

(3) Mix the solution obtained in step (1) and the emulsion obtained in step (2) at a volume ratio of 1:0.5 to 3, and magnetically stir evenly to obtain a mixed solution;

(4) Dissolve β-cyclodextrin in hot water at 40-80°C with a mass fraction of 2%-10%; add the mixture obtained in step (3) into the β-cyclodextrin solution while stirring , the volume ratio of the mixed solution to the β-cyclodextrin solution is 1:1~3, continue to homogenize under high pressure for 3~5min, filter after ultrasonication, vacuum freeze-dry, and obtain the composite amphiphilic core material Micro The finished product of capsule granules.

2. A kind of composite amphiphilic core material microcapsule granule as claimed in claim 1, characterized in that: the small peptide is soybean peptide, egg white peptide or corn peptide, and the monosaccharide is glucose or fructose, water-soluble Vitamins are ascorbic acid, thiamine, riboflavin, or niacin; lecithin is egg yolk lecithin or soybean lecithin; and fat-soluble vitamins are retinol or tocopherol.

3. A kind of compound type amphiphilic core material microcapsule granule as claimed in claim 1, characterized in that: the suction filtration adopts medium and low speed filter paper to filter and collect to obtain the filter cake.

4. A kind of compound type amphiphilic core material microcapsule granule as claimed in claim 1, it is characterized in that: vacuum freeze-drying is that the filter cake that suction filtration obtains is under vacuum tightness less than 10Pa, cold sink temperature-45～30 Dry under the condition of ℃.

5. A composite amphiphilic core material microcapsule granule as claimed in claim 1, characterized in that: ultrasonic time is 40-80 min, ultrasonic power is 300-500W, and ultrasonic temperature is 40-80°C.