CN103083429B - Blood fat-reducing traditional Chinese medicine formula - Google Patents

Abstract

The invention provides a medicine for treating hyperlipidemia, in particular a traditional Chinese medicine prescription for lowering blood fat. The traditional Chinese medicine prescription is composed of the following raw materials in parts by weight: 100-150 parts of Samara oil tree leaf extract, 50-70 parts of hawthorn extract, 100-150 parts of Shouwu extract, 80-120 parts of cassia seed extract share. Each raw material in the traditional Chinese medicine prescription is formed by drying and pulverizing raw materials, ultrasonic extraction, extraction, concentration, freeze-drying and grinding. The traditional Chinese medicine prescription of the present invention has been proved by animal experiments and clinical treatment to have strong effect of lowering blood fat. The traditional Chinese medicine of the invention is a pure natural medicine and has the advantages of fast onset of action, high cure rate and no side effects. Generally, patients with hyperlipidemia will see the effect after taking it for half a month, and the curative effect is remarkable, with the total effective rate as high as 96.5%. Properly consolidate medication after recovery, hyperlipidemia will not rebound after recovery, and can prevent complications caused by hyperlipidemia.

Description

A kind of traditional Chinese medicine composition for lowering blood fat

technical field

The invention relates to a traditional Chinese medicine prescription, which belongs to the technical field of cardiovascular disease treatment, in particular to a traditional Chinese medicine prescription for lowering blood fat.

Background technique

Blood lipids are the general term for neutral fats (triglycerides and cholesterol) and lipids (phospholipids, glycolipids, sterols, steroids) in plasma, and are essential substances for the basic metabolism of living cells. However, long-term high blood lipids will cause hyperlipidemia, that is, dyslipidemia, also known as hyperlipoproteinemia, is a systemic disease, and its basic pathophysiology is: total cholesterol (TC) in blood, triglyceride (TG) ) is too high or high-density lipoprotein cholesterol (HDL-C) is too low. Hyperlipidemia is the main factor inducing coronary heart disease, atherosclerosis, hypertension and other cardiovascular diseases. Worldwide, 17 million people (accounting for 50% of all deaths) die of cardiovascular disease every year. The pathogenesis of hyperlipidemia is closely related to genetic factors, physical lesions, eating habits, and mental state. In recent years, with the improvement of people's living standards, the proportion of high-calorie foods in the dietary structure has increased significantly, coupled with the reduction in people's activity, the incidence of hyperlipidemia has continued to increase, and the number of patients with hyperlipidemia in my country alone has reached 160 million. With an average annual increase of 15 million people on the rise. How to prevent and treat hyperlipidemia has become a health problem that people pay close attention to day by day.

At present, there are many Chinese and Western medicines for lipid-lowering clinically used at home and abroad. Western medicines such as fenofibrate, ydolate, furandrolone, statins, etc., but statins dominate. Although statins can effectively reduce serum cholesterol levels, there are reports that the drug is related to muscle lesions, etc. . Lipid-lowering Chinese patent medicines with good domestic curative effect mainly include: Jiangzhiling Tablets, Tongmai Jiangzhi Tablets, Ruanmailing Tablets, Zhibituo Tablets, Anluoning, etc. These drugs have played a great role in the treatment of hyperlipidemia. effect. However, with the increase in the number of patients with hyperlipidemia, it is still of great practical significance to develop safe and effective drugs for the prevention and treatment of hyperlipidemia to meet clinical needs.

Contents of the invention

The purpose of the present invention is in order to solve above-mentioned problem, and provides a kind of prescription of Chinese medicine for lowering blood fat.

The present invention is achieved through the following technical solutions:

A traditional Chinese medicine prescription for lowering blood fat, consisting of the following raw materials in parts by weight:

100-150 parts of Samara oil tree leaf extract, 50-70 parts of hawthorn extract, 100-150 parts of Shouwu extract, and 80-120 parts of cassia seed extract.

The extraction method of each raw material drug in the prescription is as follows:

①Extraction method of oil tree leaf extract: take leaves of oil tree samaras, dry and crush them to 60-80 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30 minutes, the amount of ethanol added is 1g leaves of oil tree Add 10-20ml of ethanol; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, extract the combined filtrate with ethyl acetate, concentrate the extract to extract, and finally freeze-dry and grind it into powder;

②Extraction method of hawthorn extract: take hawthorn, dry and crush it to 60-80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g hawthorn, add 10-20ml deionized water; repeat the above method Extract 3 times, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate to extract, and finally freeze-dry and grind into powder;

③Extraction method of Shouwu extract: take Shouwu, dry and crush it to 60-80 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min, the amount of ethanol added is 1g of Shouwu, add 10-20ml ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry and grind it into powder;

④Extraction method of cassia seed extract: choose cassia seed, dry and crush to 60-80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seed, add 10-20ml deionized water; repeat the above method Extract 3 times, combine the filtrates of the 3 times of ultrasonic extraction, extract the combined filtrates with ethyl acetate, concentrate the extract to extract, freeze-dry and grind into powder.

When the blood lipid-lowering traditional Chinese medicine is prepared according to the present invention, the preparation method is simple. After mixing the raw materials in the traditional Chinese medicine prescription of the present invention according to the stated ratio, the traditional Chinese medicine preparation method is used for preparation. At the same time, pharmaceutically acceptable auxiliary materials can also be added to give certain dosage forms, such as: capsules, tablets, granules, dropping pills, oral liquids, buccal tablets, granules, powders, suspensions, etc.

From the perspective of pharmacological activity, each raw drug component contained in the traditional Chinese medicine prescription of the present invention contains pharmacologically active ingredients that can effectively reduce blood lipids.

Samara oil tree is a bald family plant, and it is one of the relict plants after the glaciation in the fourth season of our country. Existing studies have shown that the leaves of Samara oil tree are rich in alkaloids, flavonoids, polysaccharides and terpenoids, Vc and trace elements closely related to human health; and its leaf extract has strong antioxidant activity. In addition, local residents often soak the leaves in water for drinking. Long-term drinking has the effect of lowering blood fat, lowering blood pressure, and prolonging life. In addition, animal (rat) hyperlipidemia model experiments have shown that feeding the above-mentioned leaf extract of Samara oleifera can effectively reduce the content of total cholesterol (TC) and triglyceride (TG) in rat serum (Figure 1-Figure 2 ).

The test process is as follows: ①High-fat model: Take 50 rats and feed them with high-fat diet (basic feed 78.6%, egg yolk powder 10%, cholesterol 1%, bile salt 0.2%, lard 10%, methimazole tablet 0.2 %) for 30 days, free to drink water and food every day, fasting after 30 days without water, blood lipid concentration was measured by tail vein blood collection after 12 hours, after the test passed, it was used as a hyperlipidemia model; ②Pharmacological analysis: 50 hyperlipidemia model rats were randomly divided into There are 5 groups, 10 rats in each group, set up as: model group, low, medium and high dose group (extract from leaves of Samara oleifera) and Zhibituo control group, and 10 healthy rats fed synchronously as blank control Group. Gastrointestinal administration once a day, the blank group was given the same amount of normal saline, respectively, on the 28th and 42nd day after administration, fasting without water for 12 hours before the experiment, blood was collected 2 hours after the last administration, and the blood lipid concentration was measured. In the figure, a, b, c, and d respectively represent the significant difference between groups at p<0.05.

Hawthorn is a Rosaceae plant, slightly warm in nature, sour in taste and sweet in taste. Rich in active ingredients such as triterpenoids, flavonoids, ursolic acid, saponins, and organic acids. A large number of studies have confirmed that the triterpenoids and flavonoids rich in hawthorn have the effect of dilating blood vessels and regulating blood lipid and cholesterol levels.

Shouwu is a Polygonaceae plant, slightly warm in nature, bitter, sweet and astringent. Contains stilbene glycosides, anthraquinones, flavonoids and other active ingredients that can effectively reduce blood lipid activity. Modern studies have found that making Shouwu can improve the ability of liver cells to transform and metabolize cholesterol, regulate serum cholesterol, and lower blood sugar.

Semen Cassiae is a leguminous plant, cold in nature, sweet and bitter in taste. It has the effects of expelling wind and dissipating heat, clearing the liver and brightening the day, moistening the intestines and laxative. Modern pharmacological studies have shown that Semen Cassiae has the effects of lowering blood fat and blood pressure, and its active ingredient for lowering blood fat is the anthraquinone compound it contains.

Further, the preferred parts by weight of each component raw material in the Chinese medicine prescription of the present invention are:

150 parts of Samara oil tree leaf extract, 50 parts of hawthorn extract, 150 parts of Shouwu extract, and 100 parts of cassia seed extract.

The optimal proportioning ratio of each component raw material drug in the Chinese medicine prescription of the present invention is preferably obtained by orthogonal experiments (Table 1-Table 2):

Table 1 Effects of different formula ratios on serum TC levels in hyperlipidemia model rats

Note: The serum TC content is the mean value of the test results at the end of the culture of the hyperlipidemia model rats.

Table 2 Effects of different formula ratios on serum TG levels in hyperlipidemia model rats

Note : The serum TG content is the mean value of the final test results of the high-fat model rat type culture.

As can be seen from the results of the above-mentioned orthogonal test, in the Chinese medicine prescription for lowering blood fat of the present invention, the optimal proportioning ratio of each raw material drug is: 150 parts of the leaf extract of Samara oleifera, 50 parts of the hawthorn extract, and 150 parts of the Radix Polygoni Multiflori extract. , 100 parts of cassia seed extract.

The blood fat-lowering traditional Chinese medicine prescription of the present invention has stronger blood-lipid-lowering medicinal effect, and the synergistic action of each raw material drug in the Chinese medicinal prescription has been confirmed to have stronger blood-lipid-lowering medicinal effect by animal (rat) hyperlipidemia model test analysis (Table 3):

Table 3 Effects of prescriptions on serum lipid levels in hyperlipidemic rats (mmoL ^-1 )

The traditional Chinese medicine formula for lowering blood fat of the present invention shows that no toxic reaction is seen in the tested animals (rats) after feeding the formula through animal toxicity tests, and the physiological and visceral tissues of the tested animals (rats) are compared with the normal control There was no significant difference (Table 4-Table 6), which to a certain extent shows that this Chinese medicine formula is safe and reliable.

Table 4 Effects of prescriptions on final hematological indicators in rats

The influence of table 5 prescription on rat biochemical index

The influence of table 6 prescription on rat viscera body ratio

In order to show the therapeutic effect of the traditional Chinese medicine prescription of the present invention on patients with hyperlipidemia, the present invention has undergone 86 systematic clinical observations. During the above-mentioned clinical observation process, record the medical history, condition, age and curative effect of the above-mentioned patients.

The criteria for judging clinical efficacy are:

Cure: Symptoms and signs all disappeared, and the laboratory indicators were all within the normal range.

Improvement: subjective symptoms such as chest tightness, abdominal distension, fatigue, dizziness and headache basically disappeared, and blood lipids were close to normal.

Ineffective: Symptoms, signs, and laboratory indicators have not been significantly improved.

Treatment results: 86 patients with hyperlipidemia were treated with the traditional Chinese medicine formula of the present invention, 73 patients were cured, 10 patients took a turn for the better, 3 patients were ineffective, and the total effective rate reached 96.5%.

Typical cases:

Case 1: patient Zhang, man, 38 years old, suffered from hyperlipidemia for 2 years, long-term chest tightness, palpitation, fatigue, dizziness, after taking the Chinese medicine of the present invention for eight months, the symptoms disappeared completely, and blood lipids in laboratory tests were normal. Follow up a case by regular visits to and do not recur in one year.

Case 2: patient Chen XX, female, 435 years old, suffers from hyperlipidemia, after oral medicine of the present invention six months, symptom disappears, and blood fat of laboratory test is normal. Follow up a case by regular visits to and do not recur in one year.

Case 3: patient Yang, male, 50 years old, suffered from hyperlipidemia for 3 years, and multiple treatments were ineffective. After taking the medicine of the present invention orally for one year, the symptoms disappeared, and the blood fat was normal. Follow up a case by regular visits to and do not recur in one year.

The beneficial effects of the invention are: the traditional Chinese medicine of the invention is a pure natural medicine, and has the advantages of fast onset of action, high cure rate and no side effects. Generally, patients with hyperlipidemia will see the effect after taking it for half a month, and the curative effect is remarkable, with the total effective rate as high as 96.5%. Properly consolidate medication after recovery, hyperlipidemia will not rebound after recovery, and can prevent complications caused by hyperlipidemia.

Description of drawings

Figure 1 is the effect of the leaf extract of Samara oleifera on the serum total cholesterol (TC) concentration of rats.

Figure 2 is the effect of the leaf extract of Samara oleifera on rat serum triglyceride (TG) concentration.

Detailed ways

Example 1

A traditional Chinese medicine prescription for lowering blood fat, which is composed of the following raw materials in parts by weight (each part is 1g):

Samara oil tree leaf extract 150g, hawthorn extract 50g, Shouwu extract 150g, cassia seed extract 100g.

The extraction method of each raw material in the prescription is as follows:

①Extraction method of the leaf extract of Samara oil tree: take the leaf of Samara oil tree, dry and crush it to 60 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min, the amount of ethanol added is 1g of Samara oil tree leaf and 17ml Ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 ultrasonic extractions, extract the combined filtrates with ethyl acetate, concentrate the extracts into extracts, and finally freeze-dry them and grind them into powders; ② Hawthorn extract Extraction method: take hawthorn, dry and crush to 70 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g hawthorn and add 20ml deionized water; repeat the extraction 3 times according to the above method, and 3 times ultrasonically The extracted filtrates are combined, the combined filtrates are concentrated to an extract, and finally freeze-dried and ground into a powder; ③The extraction method of the Radix Polygoni Multiflori extract: take Radix Polygoni Multiflori, dry and crush it to 74 mesh, add 60% ethanol Ultrasonic extraction at 80°C for 30 minutes, adding 14ml of ethanol to 1 g of Shouwu; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry Just grind it into powder; ④ Extraction method of cassia seed extract: take cassia seed, dry and crush to 63 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seed and 15ml deionized water; according to the above Methods The extraction was repeated 3 times, the filtrates of the 3 times of ultrasonic extraction were combined, the combined filtrates were extracted with ethyl acetate, the extract was concentrated to extract, and finally freeze-dried and ground into powder.

Mix the extract powders of the above raw materials: 150g of Samara oil tree leaf extract, 50g of hawthorn extract, 150g of Radix Polygoni Multiflori extract, and 100g of Semen Cassiae extract. That's it.

Example 2

A traditional Chinese medicine prescription for reducing blood fat, which is composed of the following raw materials in parts by weight (each part is 1kg):

Samara oil tree leaf extract 115 kg, hawthorn extract 70 kg, Shouwu extract 120 kg, cassia seed extract 90 kg.

The extraction method of each raw material in the prescription is as follows:

①Extraction method of the leaf extract of Samara oil tree: take the leaf of Samara oil tree, dry and crush it to 80 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min, the amount of ethanol added is 1g of Samara oil tree leaf and add 10ml Ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 ultrasonic extractions, extract the combined filtrates with ethyl acetate, concentrate the extracts into extracts, and finally freeze-dry them and grind them into powders; ② Hawthorn extract Extraction method: take hawthorn, dry and crush to 80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g hawthorn and add 12ml deionized water; repeat the extraction 3 times according to the above method, and 3 times ultrasonically The extracted filtrates are combined, the combined filtrates are concentrated to an extract, and finally freeze-dried and ground into a powder; ③The extraction method of the Radix Polygoni Multiflori extract: take Radix Polygoni Multiflori, dry and crush it to 60 mesh, add 60% ethanol Ultrasonic extraction at 80°C for 30 minutes, adding 10ml of ethanol to 1 g of Shouwu; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry Just grind it into powder; ④ Extraction method of cassia seed extract: take cassia seed, dry and crush to 72 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seed and 20ml deionized water; according to the above Methods The extraction was repeated 3 times, the filtrates of the 3 times of ultrasonic extraction were combined, the combined filtrates were extracted with ethyl acetate, the extract was concentrated to extract, and finally freeze-dried and ground into powder.

The extract powders of the above-mentioned raw materials were pressed: 115 kg of Samara oil tree leaf extract, 70 kg of hawthorn extract, 120 kg of Shouwu extract, and 90 kg of cassia seed extract, fully mixed, then crushed into fine powder, added starch, Microcrystalline cellulose and low-substituted cellulose are wet granulated with 70% ethanol, compressed into tablets, and coated to obtain tablets.

Example 3

A traditional Chinese medicine prescription for reducing blood fat, which is composed of the following raw materials in parts by weight (each part is 1 tael):

Samara oil tree leaf extract 100 taels, hawthorn extract 65 taels, Shouwu extract 135 taels, cassia seed extract 80 taels.

The extraction method of each raw material in the prescription is as follows:

①Extraction method of the leaf extract of Samara oil tree: Take the leaf of Samara oil tree, dry and crush it to 75 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30 minutes, the amount of ethanol added is 1g of Samara oil tree leaf and add 13ml Ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 ultrasonic extractions, extract the combined filtrates with ethyl acetate, concentrate the extracts into extracts, and finally freeze-dry them and grind them into powders; ② Hawthorn extract Extraction method: take hawthorn, dry and crush it to 65 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g hawthorn and add 10ml deionized water; repeat the extraction 3 times according to the above method, and 3 times ultrasonically The extracted filtrates are combined, the combined filtrates are concentrated to an extract, and finally freeze-dried and ground into a powder; ③The extraction method of the Radix Polygoni Multiflori extract: take Radix Polygoni Multiflori, dry and crush it to 80 mesh, add 60% ethanol Ultrasonic extraction at 80°C for 30 minutes, the amount of ethanol added is 1 g of Shouwu, and 20 ml of ethanol is added; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry Grind into powder; ④Extraction method of cassia seed extract: take cassia seed, dry and crush to 80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seed and 17ml deionized water; according to the above Methods The extraction was repeated 3 times, the filtrates of the 3 times of ultrasonic extraction were combined, the combined filtrates were extracted with ethyl acetate, the extract was concentrated to extract, and finally freeze-dried and ground into powder.

The extract powders of the above raw materials were mixed according to: 100 taels of Samara oil tree leaf extract, 65 taels of hawthorn extract, 135 taels of Zhishouwu extract, and 80 taels of cassia seed extract, and then pulverized into fine powder. The method can be made into capsules.

Example 4

A traditional Chinese medicine prescription for reducing blood fat, which is composed of the following raw materials in parts by weight (each part is 1 catties):

Samara oil tree leaf extract 140 catties, hawthorn extract 60 catties, Shouwu extract 100 catties, cassia seed extract 120 catties.

The extraction method of each raw material in the prescription is as follows: Extraction method of the leaf extract of Samara oil tree: take the leaf of Samara oil tree, dry and crush to 65 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min, the amount of ethanol added Add 20ml of ethanol to 1g of Samara oil tree leaves; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, extract the combined filtrate with ethyl acetate, concentrate the extract to extract, finally freeze-dry and grind It can be made into powder; ②Extraction method of hawthorn extract: take hawthorn, dry and crush to 60 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g hawthorn and 18ml deionized water; according to the above method Repeat the extraction 3 times, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry it and grind it into powder; To 67 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min. The amount of ethanol added is 1g of Shouwu and 18ml of ethanol is added; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, and concentrate the combined filtrate To the extract form, finally freeze-dried and ground into powder; ④ Extraction method of cassia seed extract: take cassia seed, dry and crush to 60 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g Add 10ml of deionized water to the cassia seeds; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, extract the combined filtrates with ethyl acetate, concentrate the extracts into extracts, and finally freeze-dry them and grind them into powders .

The extract powders of the above-mentioned raw materials are pressed: 140 jin of Samara oleifera leaf extract, 60 jin of hawthorn extract, 100 jin of Shouwu extract, 120 jin of cassia seed extract, and make oral liquid according to the conventional method. Can.

Claims (3)

1. A Chinese medicine composition for lowering blood fat, characterized in that it is made up of the following raw materials in parts by weight: 100-150 parts of samara leaf extract, 50-70 parts of hawthorn extract, 100-100 parts of Shouwu extract 150 parts, 80-120 parts of cassia seed extract; wherein, the extraction method of each raw material in the prescription is as follows: 1. the extraction method of the leaf extract of Samara oil tree: get the leaf of Samara oil tree, dry and pulverize to 60-80 mesh, Add 60% ethanol and ultrasonically extract at 80°C for 30 minutes. The amount of ethanol added is 10-20ml of ethanol for 1g of Samara oleifera leaves; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, and pass the combined filtrate through acetic acid Ethyl ester extraction, concentrate the extract to extract, and finally freeze-dry and grind into powder; ②Extraction method of hawthorn extract: take hawthorn, dry and crush to 60-80 mesh, add deionized water in boiling water and ultrasonic Extract for 40min, add 10-20ml of deionized water to 1g of hawthorn; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry and grind It can be made into powder; ③Extraction method of Radix Polygoni Multiflori extract: take Radix Polygoni Multiflori, dry and crush it to 60-80 mesh, add 60% ethanol and extract ultrasonically at 80°C for 30min, the amount of ethanol added is 1g Radix Polygoni Multiflori 10-20ml of ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry and grind it into powder; ④ Extraction method of cassia seed extract: take Cassia seeds, dry and crush to 60-80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seeds, add 10-20ml deionized water; repeat the extraction 3 times according to the above method, and 3 times ultrasonic extraction The filtrates were combined, the combined filtrates were extracted with ethyl acetate, the extract was concentrated to extract, and finally freeze-dried and ground into powder. 2. A kind of Chinese medicine composition for lowering blood fat according to claim 1, characterized in that it is composed of the following raw materials in parts by weight: 150 parts of samara leaf extract, 50 parts of hawthorn extract, Shouwu extract 150 parts, 100 parts of Cassia seed extract; Among them, the extraction method of each raw material in the prescription is as follows: ①Extraction method of the leaf extract of Samara oil tree: take the leaf of Samara oil tree, dry and pulverize to 60-80 mesh, add Ultrasonic extraction with 60% ethanol at 80°C for 30 minutes, the amount of ethanol added is 10-20ml of ethanol for 1g of Samara oil tree leaves; repeat the extraction 3 times according to the above method, combine the filtrates of the 3 ultrasonic extractions, and pass the combined filtrates through ethyl acetate Ester extraction, concentrate the extract to an extract, and finally freeze-dry and grind it into powder; ②Extraction method of hawthorn extract: take hawthorn, dry and crush it to 60-80 mesh, add deionized water and ultrasonically extract in boiling water 40min, the amount of deionized water added is 1g hawthorn and 10-20ml deionized water; repeat the extraction 3 times according to the above method, combine the filtrates from the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry it and grind it into powder; ③Extraction method of Shouwu extract: take Shouwu, dry and crush it to 60-80 mesh, add 60% ethanol and ultrasonically extract at 80°C for 30min, the amount of ethanol added is 1g Shouwu and add 10 -20ml ethanol; Repeat the extraction 3 times according to the above method, combine the filtrates of the 3 times of ultrasonic extraction, concentrate the combined filtrate into an extract, and finally freeze-dry and grind it into powder; , dry and pulverize to 60-80 mesh, add deionized water and ultrasonically extract in boiling water for 40min, the amount of deionized water added is 1g cassia seed and add 10-20ml deionized water; repeat the extraction 3 times according to the above method, and the 3 times ultrasonically extracted The filtrates are combined, the combined filtrates are extracted with ethyl acetate, the extract is concentrated to extract, and finally freeze-dried and ground into powder. 3. A kind of Chinese medicine composition for reducing blood fat according to claim 1 or 2, characterized in that: the prescription is made into capsules, tablets, dropping pills, oral liquids, granules, powders, and suspensions.