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CN103028044B - Paste for treating burns and scalds - Google Patents

Paste for treating burns and scalds Download PDF

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Publication number
CN103028044B
CN103028044B CN201210534847.9A CN201210534847A CN103028044B CN 103028044 B CN103028044 B CN 103028044B CN 201210534847 A CN201210534847 A CN 201210534847A CN 103028044 B CN103028044 B CN 103028044B
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parts
ointment
coarse powder
calamine
scalds
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CN103028044A (en
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张幸国
赵青威
洪东升
张相宜
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Zhejiang University ZJU
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Abstract

本发明公开了一种治疗烧烫伤的膏剂,由以下重量份的原料制成: 鸭跖草10—20份;生石膏 5-15份;红藤 10-30份;山慈菇 5-15份;炉甘石 2-10份;乳香 2-5份;没药 2-5份;菜籽油 50-100份。本发明采用清热解毒药、清热泻火药、活血化瘀药和拔毒化腐生肌药配以甘温的菜籽油进行熬制成膏剂,涂于烧烫伤疮面后能有效缓解烧烫伤带来的疼痛感,并能起到防止伤口感染及促进烧烫伤组织再生的作用。The invention discloses an ointment for treating burns and scalds, which is prepared from the following raw materials in parts by weight: 10-20 parts of Commelina chinensis; 5-15 parts of raw gypsum; 10-30 parts of red rattan; 5-15 parts of Shanzi mushroom; 2-10 parts of calamine; 2-5 parts of frankincense; 2-5 parts of myrrh; 50-100 parts of rapeseed oil. In the present invention, heat-clearing and detoxifying medicine, heat-clearing and gunpowder medicine, blood-activating and stasis-removing medicine and detoxification-dissolving saprophytic-invigorating medicine are used together with sweet and warm rapeseed oil to make ointment. Pain, and can play a role in preventing wound infection and promoting regeneration of burnt tissue.

Description

一种治疗烧烫伤的膏剂Ointment for treating burns

技术领域 technical field

本发明涉及一种中药膏剂,具体涉及一种治疗烧烫伤的膏剂。The invention relates to a traditional Chinese medicine ointment, in particular to an ointment for treating burns and scalds.

背景技术 Background technique

烧烫伤是日常生活中常见的一类机体损失,它是由火焰、热流体、电、化学物质等作用于机体而引起的急性损伤性疾病,中医学称其为“水火烫伤”。烧烫伤根据损伤程度分为4个等级:I度损伤,为表皮角质层、透明层、颗粒层的损伤,局部红肿,故又称“红斑性损伤”;浅II度损伤,到达真皮层的表面(乳头层),表面发红,同时带有清水泡,如压迫会发白;深II度损伤,到达真皮层的深层(网状层),表面又红又白,带有出血的水泡;III度损伤,热力伤害穿透整个真皮层,表面发白、发硬。Burns are a common type of body loss in daily life. It is an acute injury disease caused by the action of flames, thermal fluids, electricity, and chemical substances on the body. Traditional Chinese medicine calls it "water and fire burns". Burns and scalds are divided into 4 grades according to the degree of injury: I degree injury, which is the injury of the stratum corneum, translucent layer, and granular layer of the epidermis, with local redness and swelling, so it is also called "erythematous injury"; shallow II degree injury, reaching the surface of the dermis (papillary layer), the surface is red with clear blisters, and will turn white if pressed; deep second-degree damage, reaching the deep layer of the dermis (reticular layer), the surface is red and white, with bleeding blisters; III Degree of damage, heat damage penetrates the entire dermis, and the surface turns white and hard.

烧伤处局部组织坏死、血管栓塞、局部血运差,局部用药优于全身用药,因此外用药物在烧烫伤的治疗中占有重要的地位。目前临床上用于治疗烧烫伤的外用药物主要包括防止感染、促进创面愈合、加速成痂及活血化瘀类药物,但是这些药物在临床治疗中存在创面疼痛、进行性坏死、易感染这三大技术难题,因此迫切需要寻找更为有效的药物。Local tissue necrosis, vascular embolism, and poor local blood supply at the burn site, local medication is better than systemic medication, so external medication occupies an important position in the treatment of burns and scalds. At present, the external medicines used clinically to treat burns and scalds mainly include medicines for preventing infection, promoting wound healing, accelerating scab formation and promoting blood circulation and removing blood stasis. Due to technical difficulties, there is an urgent need to find more effective drugs.

发明内容 Contents of the invention

为解决上述问题,本发明的目的是提供一种抗菌、缓解疼痛、促进烧烫伤处组织再生的中药外用膏剂,主要用于治疗I度烧烫伤和浅II度烧烫伤。In order to solve the above problems, the object of the present invention is to provide a kind of traditional Chinese medicine external application ointment which is antibacterial, relieves pain, and promotes the tissue regeneration of burns and scalds, and is mainly used in the treatment of first-degree burns and shallow second-degree burns.

为了实现上述目的,本发明采用以下技术方案:In order to achieve the above object, the present invention adopts the following technical solutions:

一种治疗烧烫伤的膏剂,所述膏剂由以下重量份的原料制成: 鸭跖草10—20份;生石膏 5-15份;红藤 10-30份;山慈菇 5-15份;炉甘石 2-10份;乳香 2-5份;没药 2-5份;菜籽油 50-100份。An ointment for treating burns and scalds, the ointment is made of the following raw materials in parts by weight: 10-20 parts of Commelina chinensis; 5-15 parts of raw gypsum; 10-30 parts of red rattan; 5-15 parts of Shanzi mushroom; Calamus 2-10 parts; frankincense 2-5 parts; myrrh 2-5 parts; rapeseed oil 50-100 parts.

进一步,所述膏剂用于治疗I度烧烫伤时,所述膏剂优选由以下重量份的原料制成:鸭跖草10份;生石膏10份;红藤20份;山慈菇 10份;炉甘石 5份;乳香 3份;没药3份;菜籽油70份。Further, when the ointment is used to treat first-degree burns, the ointment is preferably made of the following raw materials in parts by weight: 10 parts of Commelina chinensis; 10 parts of raw gypsum; 20 parts of red rattan; 10 parts of Arrowhead mushroom; 5 parts of stone; 3 parts of frankincense; 3 parts of myrrh; 70 parts of rapeseed oil.

所述膏剂用于治疗浅II度烧烫伤时,所述膏剂优选由以下重量份的原料制成:鸭跖草 15份;生石膏15份;红藤25份;山慈菇15份;炉甘石8份;乳香5份;没药5份;菜籽油70份。When the ointment is used to treat superficial second-degree burns, the ointment is preferably made of the following raw materials in parts by weight: 15 parts of Commelina chinensis; 15 parts of raw gypsum; 25 parts of red rattan; 15 parts of Arrowhead mushroom; calamine 8 parts; frankincense 5 parts; myrrh 5 parts; rapeseed oil 70 parts.

本发明涉及的中药原料均为药物原料药批发市场中可直接购得的原料,如鸭跖草、红藤、山慈菇、乳香、没药均是指中医药中选用的入药部位,本领域技术人员都能理解这些原料来源。The raw materials of traditional Chinese medicine involved in the present invention are the raw materials that can be directly purchased in the raw material drug wholesale market, such as Commelina chinensis, red rattan, Arrowhead mushroom, frankincense, and myrrh all refer to the medicinal parts selected in traditional Chinese medicine. Those of skill in the art will understand the sources of these raw materials.

本发明还提供所述的膏剂的制备方法,所述方法为:按照组方重量配比称取原料,将生石膏、红藤、山慈菇、炉甘石分别粉碎成粗粉,红藤粗粉、山慈菇粗粉、炉甘石粗粉加入100℃的菜籽油中煎煮3~5个小时,然后加入鸭跖草、乳香、没药再于100℃煮30~60分钟,最后加入生石膏粗粉100℃煮15~20分钟,趁热过滤去渣,滤液冷却后装瓶,即得到所述治疗烧烫伤的膏剂。The present invention also provides the preparation method of the ointment. The method is as follows: weighing the raw materials according to the weight ratio of the formula, and crushing raw gypsum, red rattan, Arrowhead mushroom and calamine respectively into coarse powder, red rattan coarse powder , Shanzi mushroom coarse powder, and calamine coarse powder are added to 100°C rapeseed oil and decocted for 3-5 hours, then add commelina, frankincense, and myrrh and cook at 100°C for 30-60 minutes, and finally add Coarse raw gypsum powder is boiled at 100°C for 15-20 minutes, filtered while hot to remove slag, and the filtrate is bottled after cooling to obtain the ointment for treating burns and scalds.

根据传统中医药理论,本发明所选取的原料药物的功效和药理作用分别是:鸭跖草具有清热解毒、利水消肿的功效;生石膏能清热、收敛生肌;红藤具有清热解毒、活血止痛的功效;山慈菇具有清热解毒、消痈散结的功效;炉甘石具有解毒、收敛生肌敛疮的作用;乳香具有活血行气止痛、消肿生肌的功效;没药具有活血止痛、消肿生肌的功效;菜籽油味甘、辛,性温,具有散火单、消肿毒的功效,并能隔离细菌、保护烧烫伤的疮面,是良好的药物组分载体。According to the theory of traditional Chinese medicine, the efficacy and pharmacological effects of the raw materials selected in the present invention are respectively: Commelina chinensis has the effects of clearing away heat and detoxifying, diuresis and detumescence; Arrowhead mushroom has the effect of clearing heat and detoxifying, eliminating carbuncle and resolving stagnation; calamine has the effect of detoxification, astringent and promoting muscle regeneration; frankincense has the effect of promoting blood circulation, promoting qi and relieving pain, reducing swelling and promoting muscle; myrrh has the effect of promoting blood circulation and relieving pain , the effect of reducing swelling and promoting muscle growth; rapeseed oil is sweet, pungent, and warm in nature.

本发明所述的一种治疗烧烫伤的中药外用膏剂其有益效果在于:本发明采用清热解毒药、清热泻火药、活血化瘀药和拔毒化腐生肌药配以甘温的菜籽油进行熬制成膏剂,涂于烧烫伤疮面后能有效缓解烧烫伤带来的疼痛感,并能起到防止伤口感染及促进烧烫伤组织再生的作用;使用上述制剂对92例烧烫患者进行治疗,使用30分钟后89例患者的疼痛感明显减轻,使用30天后85列患者基本痊愈并未出现感染,治愈率达到92%;同时上述制剂所需的原料药物比较容易获得,药物成本较低,可降低烧烫伤患者的就医费用。The beneficial effects of the traditional Chinese medicinal ointment for treating burns and scalds according to the present invention are: the present invention uses heat-clearing and detoxifying medicines, heat-clearing and gunpowder medicines, blood-activating and stasis-removing medicines, and detoxification-dissolving saprophytic-muscle-promoting medicines together with sweet and warm rapeseed oil for boiling Made into ointment, it can effectively relieve the pain caused by burns and scalds after being applied to the surface of burns and scalds, and can prevent wound infection and promote the regeneration of burns and scalds; use the above preparation to treat 92 burn patients, After 30 minutes of use, the pain of 89 patients was significantly relieved. After 30 days of use, 85 patients were basically cured without infection, and the cure rate reached 92%. Reduce the cost of medical treatment for patients with burns and scalds.

具体实施方式Detailed ways

下面具体实施里来对本发明进行详细说明,但本发明的保护范围不限于此。The present invention will be described in detail in the following specific implementation, but the protection scope of the present invention is not limited thereto.

实施列1Implementation column 1

称取如下重量份数的原料:鸭跖草,10g;生石膏,10g;红藤,20g;山慈菇,10g;炉甘石,5g;乳香,3g;没药,3g;菜籽油,70g;将生石膏、红藤、山慈菇、炉甘石分别粉碎成粗粉,然后将菜籽油加热到100℃,加入红藤粗粉、山慈菇粗粉、炉甘石粗粉煎煮3个小时,然后加入鸭跖草、乳香、没药再于100℃煮半个小时,最后加入生石膏粗粉100℃煮15分钟,趁热过滤去渣,滤液冷却后放入备用瓶中即为治疗烧烫伤的中药膏剂成品,适合治疗I度烧烫伤。Weigh the following raw materials in parts by weight: commelina, 10g; raw gypsum, 10g; red rattan, 20g; shanzi mushroom, 10g; calamine, 5g; frankincense, 3g; myrrh, 3g; rapeseed oil, 70g ; Pulverize raw gypsum, red rattan, Arrowhead mushroom, and calamine into coarse powder respectively, then heat rapeseed oil to 100°C, add red rattan coarse powder, Arrowhead mushroom coarse powder, calamine coarse powder and decoct for 3 Then add commelina, frankincense, and myrrh and cook at 100°C for half an hour. Finally, add raw gypsum coarse powder and cook at 100°C for 15 minutes. Filter while it is hot to remove residue. After the filtrate is cooled, put it into a spare bottle for treatment. The finished product of traditional Chinese medicine ointment for burns and scalds is suitable for treating first-degree burns and scalds.

实施例2Example 2

称取如下重量配比的原料:鸭跖草,15g;生石膏,15g;红藤,25g;山慈菇,15g;炉甘石,8g;乳香,5g;没药,5g;菜籽油,70g;将生石膏、红藤、山慈菇、炉甘石分别粉碎成粗粉,然后将菜籽油加热到100℃,加入红藤粗粉、山慈菇粗粉、炉甘石粗粉煎煮3个小时,然后加入鸭跖草、乳香、没药再于100℃煮半个小时,最后加入生石膏粗粉于100℃煮15分钟,趁热过滤去渣,滤液冷却后放入备用瓶中即为治疗烧烫伤的中药膏剂成品,,适合治疗浅II度烧烫伤。Weigh the raw materials with the following weight ratio: commelina, 15g; raw gypsum, 15g; red rattan, 25g; mountain arrowhead, 15g; calamine, 8g; frankincense, 5g; myrrh, 5g; rapeseed oil, 70g ; Pulverize raw gypsum, red rattan, Arrowhead mushroom, and calamine into coarse powder respectively, then heat rapeseed oil to 100°C, add red rattan coarse powder, Arrowhead mushroom coarse powder, calamine coarse powder and decoct for 3 Then add commelina, frankincense, and myrrh and cook at 100°C for half an hour. Finally, add raw gypsum coarse powder and cook at 100°C for 15 minutes. The finished product of traditional Chinese medicine ointment for treating burns and scalds is suitable for treating superficial second-degree burns and scalds.

为表明本发明的应用效果,本发明经临床观察,结果如下:For showing the application effect of the present invention, the present invention is through clinical observation, and result is as follows:

一、资料和方法1. Materials and methods

1、一般资料1. General Information

在92例确诊为I度烧烫伤和浅II度烧烫伤的患者中,62%为女性,年龄在25-55岁之间,平均年龄32.5岁,其中I度烧烫伤患者55例,浅II度烧烫伤患者37例。Among the 92 patients diagnosed with first-degree burns and superficial second-degree burns, 62% were women, aged between 25 and 55, with an average age of 32.5 years, of which 55 were patients with first-degree burns and superficial second-degree burns. 37 patients with burns and scalds.

2、治疗方法2. Treatment method

用实施例1制得的药物对55例I度烧烫伤患者进行治疗,实施例2制得的药物对37例浅II度烧烫伤患者进行治疗,治疗方法是将药物涂抹在伤口处,药物的涂抹量要求是药膏能覆盖伤口表面,1天3次。Treat 55 patients with first-degree burns and scalds with the medicine prepared in Example 1, and treat 37 patients with shallow second-degree burns and scalds with the medicine prepared in Example 2. The treatment method is to smear the medicine on the wound. The amount of application required is that the ointment can cover the surface of the wound, 3 times a day.

3、结果3. Results

用实施例1的药物对55例I度烧烫伤患者进行治疗,30分钟后患者的疼痛感消失,使用7天后,52患者烧伤处的红肿基本消失,治愈率达到95%;实施例2的药物对37例浅II度烧烫伤患者进行治疗,30分钟后34例患者感到疼痛感明显减轻,治疗30天后,33例患者症状基本消失,治愈率达到89%。下面是列举了几个典型病例。Treat 55 routine I degree burn patients with the medicine of embodiment 1, the patient's pain disappears after 30 minutes, use after 7 days, the redness and swelling of 52 patients' burns disappears substantially, and the cure rate reaches 95%; The medicine of embodiment 2 37 patients with superficial second-degree burns were treated. After 30 minutes, 34 patients felt that the pain was significantly relieved. After 30 days of treatment, the symptoms of 33 patients basically disappeared, and the cure rate reached 89%. A few typical cases are listed below.

典型病例1Typical case 1

李某,女,37岁,浙江省杭州市萧山区农民,于2010年9月在家中烧开水,碰翻了烧水壶,造成腿部烫伤,就诊时患者感觉烫伤处觉得像“针刺”一样的,并伴有表面红肿,轻压发白,诊断为浅II度烫伤,用实施例2制得的药物涂抹于烫伤处,30分钟后,患者“针刺”的感觉消失,连续使用22天后,患者症状基本消失。Li, female, 37 years old, a farmer in Xiaoshan District, Hangzhou City, Zhejiang Province, boiled water at home in September 2010 and knocked over the kettle, resulting in burns on her legs. and accompanied by surface redness and swelling, whitish under light pressure, diagnosed as shallow II degree burn, applied the medicine prepared in Example 2 to the scald, and after 30 minutes, the patient's "acupuncture" sensation disappeared, and after continuous use for 22 days , the patient's symptoms basically disappeared.

典型病例2Typical case 2

吴某,男,22岁,浙江省杭州市西湖区留下镇人,于2010年7月在饭店用餐时,不慎将热汤打翻在脚上,造成脚板烫伤,就诊时,患者脚板处感觉“火辣辣”的,表面出现红斑,确诊为I度烫伤,采用实施例1制得的药物涂抹于烫伤处,15分钟后,患者“火辣辣”的感觉消失,连续使用14天后,患者症状基本消失。Wu, male, 22 years old, a resident of Liuliu Town, Xihu District, Hangzhou City, Zhejiang Province, in July 2010, while eating at a restaurant, he accidentally spilled hot soup on his feet, causing burns on his feet. Feel " hot ", erythema appears on the surface, be diagnosed as I degree scald, adopt the medicine that embodiment 1 makes to smear on scald, after 15 minutes, patient's " hot " sensation disappears, and after 14 days of continuous use, patient's symptom disappears substantially .

以上所述,仅是本发明的较佳实施例,并非对本发明做任何限制,凡是根据本发明技术实质对以上实施所作的任何简单修改、变更以及等效结构变化,均仍属于本发明技术方案的保护范围内。The above descriptions are only preferred embodiments of the present invention, and do not limit the present invention in any way. All simple modifications, changes and equivalent structural changes made to the above implementations according to the technical essence of the present invention still belong to the technical solution of the present invention. within the scope of protection.

Claims (4)

1.一种治疗烧烫伤的膏剂,其特征在于所述膏剂由以下重量份的原料制成:鸭跖草10—20份;生石膏5-15份;红藤10-30份;山慈菇5-15份;炉甘石2-10份;乳香2-5份;没药2-5份;菜籽油50-100份;1. a kind of ointment for the treatment of burns and scalds, is characterized in that described ointment is made of the raw material of following weight portion: commelina 10-20 parts; Gypsum 5-15 parts; Red Vine 10-30 parts; Shanzi mushroom 5 parts -15 parts; 2-10 parts of calamine; 2-5 parts of frankincense; 2-5 parts of myrrh; 50-100 parts of rapeseed oil; 所述的膏剂按以下方法制得:按照组方重量配比称取原料,将生石膏、红藤、山慈菇、炉甘石分别粉碎成粗粉,红藤粗粉、山慈菇粗粉、炉甘石粗粉加入100℃的菜籽油中煎煮3~5个小时,然后加入鸭跖草、乳香、没药再于100℃煮30~60分钟,最后加入生石膏粗粉100℃煮15~20分钟,趁热过滤去渣,滤液冷却后装瓶,即得到所述治疗烧烫伤的膏剂。The ointment is prepared as follows: raw materials are weighed according to the weight ratio of the formula, and raw gypsum, red rattan, mountain arrowhead, and calamine are respectively pulverized into coarse powder, red rattan coarse powder, mountain arrowroot coarse powder, Add calamine coarse powder to rapeseed oil at 100°C and cook for 3 to 5 hours, then add commelina, frankincense, and myrrh and cook at 100°C for 30 to 60 minutes, and finally add raw gypsum coarse powder and cook at 100°C for 15 hours. After ~20 minutes, filter while hot to remove the slag, and bottle the filtrate after cooling to obtain the ointment for treating burns and scalds. 2.如权利要求1所述的膏剂,其特征在于所述膏剂用于治疗I度烧烫伤,所述膏剂由以下重量份的原料制成:鸭跖草10份;生石膏10份;红藤20份;山慈菇10份;炉甘石5份;乳香3份;没药3份;菜籽油70份。2. the ointment as claimed in claim 1, is characterized in that said ointment is used for the treatment of first-degree burns and scalds, and described ointment is made of the raw material of following parts by weight: 10 parts of commelina; 10 parts of raw gypsum; 20 parts of red rattan 10 parts of Shanzi mushroom; 5 parts of calamine; 3 parts of frankincense; 3 parts of myrrh; 70 parts of rapeseed oil. 3.如权利要求1所述的膏剂,其特征在于所述膏剂用于治疗浅II度烧烫伤,所述膏剂由以下重量份的原料制成:鸭跖草15份;生石膏15份;红藤25份;山慈菇15份;炉甘石8份;乳香5份;没药5份;菜籽油70份。3. The ointment as claimed in claim 1, wherein said ointment is used for the treatment of shallow second-degree burns, and said ointment is made of the following raw materials in parts by weight: 15 parts of Commelina chinensis; 15 parts of raw gypsum; 25 parts; 15 parts of Shanzi mushroom; 8 parts of calamine; 5 parts of frankincense; 5 parts of myrrh; 70 parts of rapeseed oil. 4.如权利要求1~3之一所述的膏剂的制备方法,其特征在于所述方法为:按照组方重量配比称取原料,将生石膏、红藤、山慈菇、炉甘石分别粉碎成粗粉,红藤粗粉、山慈菇粗粉、炉甘石粗粉加入100℃的菜籽油中煎煮3~5个小时,然后加入鸭跖草、乳香、没药再于100℃煮30~60分钟,最后加入生石膏粗粉100℃煮15~20分钟,趁热过滤去渣,滤液冷却后装瓶,即得到所述治疗烧烫伤的膏剂。4. The preparation method of ointment as claimed in any one of claims 1 to 3, characterized in that the method is: taking the raw materials according to the weight ratio of the prescription, and taking raw gypsum, red rattan, Arrowhead mushroom and calamine respectively Grind into coarse powder, add red rattan coarse powder, mountain arrowroot coarse powder, and calamine coarse powder to rapeseed oil at 100°C and decoct for 3 to 5 hours, then add commelina, frankincense, and myrrh at 100 Cook at 100°C for 30 to 60 minutes, finally add raw gypsum coarse powder and cook at 100°C for 15 to 20 minutes, filter while hot to remove residue, and bottle the filtrate after cooling to obtain the ointment for treating burns and scalds.
CN201210534847.9A 2012-12-08 2012-12-08 Paste for treating burns and scalds Expired - Fee Related CN103028044B (en)

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CN103239512A (en) * 2013-04-28 2013-08-14 陈爱玲 Plaster for treating scalds
CN104721254A (en) * 2015-03-27 2015-06-24 姜启禹 Skin healing and tissue regeneration cream

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CN102526438A (en) * 2012-02-24 2012-07-04 阳俊才 Drug for treating burn and scald and preparation method of same
CN102579763A (en) * 2012-03-12 2012-07-18 高永学 Externally applied traditional Chinese medicine composition for treating burns and scalds
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CN1157724A (en) * 1995-12-07 1997-08-27 吴远界 Ointment for treatment of burn and scald
CN1444967A (en) * 2003-04-16 2003-10-01 吉林敖东延边药业股份有限公司 Chinese herbal medicine preparation for treating burns
CN1785335A (en) * 2005-02-28 2006-06-14 张岚 Pure Chinese medicinal preparation for external treating burn and scald
CN101244109A (en) * 2008-03-21 2008-08-20 冯九玉 Natural Chinese medicine of oil-water liniment for treating burn and scald, and preparation thereof
CN102008612A (en) * 2010-11-25 2011-04-13 黄书芳 Medicament for treating empyrosis and preparation method thereof
CN102652763A (en) * 2011-03-01 2012-09-05 上海交通大学医学院附属第三人民医院 Traditional Chinese medicine preparation for treating burn and scald and preparation method thereof
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