CN102986701B - Insecticidal composition containing cycloxaprid and chlorfluazuron and application of composition - Google Patents

Abstract

The invention relates to the field of agricultural insecticide preparations, in particular to an insecticide composition containing cycloxamid and chlorfluazuron and its application. The insecticidal composition containing cyclofluazuron and chlorfluazuron of the present invention, the insecticidal composition includes cyclofluazuron and chlorfluazuron, and the weight ratio of the cycloclofenac and the chlorfluazuron is 1:30~30:1. Compared with the prior art, the two active ingredients of the insecticidal composition of the present invention have different mechanisms of action, which can delay the generation of insecticide resistance, reduce the amount of pesticides used in the field, effectively reduce environmental pollution and pesticide residues, and further reduce the Hazard to beneficial organisms.

Description

A kind of insecticidal composition containing cyclopyrid and chlorfluazuron and its application

technical field

The invention relates to the field of agricultural insecticide preparations, in particular to an insecticide composition containing cycloxamid and chlorfluazuron and its application.

Background technique

Cyclopyrid is a new neonicotinoid insecticide. Cyclopyrid is the first nAChR antagonist in the world, and it is very likely to become a new class of insecticide with important influence in the world, and its activity is significantly better than that of imidacloprid. It is highly effective against rice brown planthopper, white-backed planthopper, and brown planthopper, and also has good control effects on cabbage aphids and cucumber aphids, and has a good concurrent control effect on rice leaf rollers. In addition, its bee toxicity is also significantly reduced. The 48-hour acute intake LC ₅₀ of cyclocloprid is 19.18mg/L, while that of imidacloprid is 4.94mg/L. The toxicity is significantly lower than that of imidacloprid, which improves the environmental safety. In addition, it shows excellent activity against tapeworms and coccidia of sheep and rabbits. As a new type of neonicotinoid insecticide, cycloxaprid has the risk of high cost of use and gradually increasing risk of resistance after it is launched on the market. poor.

Chlorfluazuron, as a benzoylurea insecticide, has the biological activity of anti-ecdysone, can inhibit the activation rate of insect epidermal chitin synthase and uridine coenzyme, and inhibit the activation rate of N-acetylglucosamine in several Combining with chitin can affect the respiratory metabolism of eggs and DNA and protein metabolism during embryonic development, so that larvae in eggs cannot hatch or die immediately after hatching due to lack of chitin; application at the larval stage hinders the formation of new epidermis of pests , Delayed development, or lack of hardness, unable to molt normally and lead to death or death of deformed pupae. Chlorfluazuron mainly controls resistant pests of Lepidoptera and Homoptera. It has the advantages of high efficiency, low toxicity and long lasting effect when used in the field to control pests. However, there are disadvantages of poor quick-acting property and high drug cost.

Insecticide varieties containing a single active ingredient often have varying degrees of defects in the control of agricultural pests: pests are prone to develop resistance after continuous use, and frequent use will aggravate environmental pollution. The compounding of different components can effectively overcome the above shortcomings. At the same time, using the synergistic effect produced by the mixing of the two active components can improve the control effect, reduce the amount of active ingredients, save the cost of medication, delay the generation of insecticide resistance of pests and pest mites, and reduce environmental pollution. important means. At present, no one has reported the compounding and application of cycloclofenac and chlorfluazuron.

Contents of the invention

The purpose of the present invention is to provide an insecticidal composition containing cycloxapamid and chlorfluazuron, so as to solve the technical problems in the prior art when cycloxapamid and chlorfluazuron are used alone.

Another object of the present invention is to provide the application of the above insecticidal composition containing cyclopyrid and chlorfluazuron.

The object of the invention is achieved through the following technical solutions:

A kind of insecticidal composition containing cyclofluazuron and chlorfluazuron, the insecticidal composition includes cycloclofenac and chlorfluazuron, and the weight ratio of the cycloclofenac and the chlorfluazuron is 1 :30~30:1.

Preferably, the weight ratio of cycloxaprid to the chlorfluazuron is 1:20-20:1.

Preferably, the weight ratio of cycloxaprid to the chlorfluazuron is 1:10-10:1.

Preferably, the weight ratio of cycloxaprid to the chlorfluazuron is 1:1.

Preferably, the pesticidal composition is made into wettable powder, suspension, water dispersible granule or water emulsion.

The above insecticidal composition containing cyclopyrid and chlorfluazuron is used for controlling Homoptera pests and Lepidoptera pests.

Preferably, the homopteran pests include brown planthopper and white-backed planthopper; and the lepidopteran pests include beet armyworm.

Compared with the prior art, the present invention has the following beneficial effects:

1. The two active ingredients of the insecticidal composition of the present invention have different mechanisms of action, which can delay the generation of insecticide resistance, reduce the amount of pesticides used in the field, effectively reduce environmental pollution and pesticide residues, and further reduce the harm to beneficial organisms ;

2. The insecticidal composition of the present invention can expand the control spectrum in application, and can control multiple pests at the same time through one application, thereby reducing farmers' control costs and having significant economic and social benefits;

3. The insecticidal composition of the present invention has a synergistic effect on pests, can improve the control effect, and reduce the dosage and cost of pesticides.

Detailed ways

Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the teachings of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined by the appended claims of the present application.

Example 1

Determination of Toxicity of Cyclopyrid, Chlorfluazuron and Mixtures with Different Proportions to Beet Spodoptera

Use the leaf dipping method. Cut the leaves of cabbage into discs of the same size, wash them and dip them in the prepared medicinal solution for 10 seconds, and use distilled water (containing 0.1% TritonX-100) as a control. After the treated leaves were dried at room temperature, the 3rd instar larvae of beet armyworm (starvation for 4 hours) were picked up, each concentration was repeated 3 times, and 20 larvae were picked up each time, placed in an artificial climate box, 27°C, L:D It was 14:10. The mortality of larvae was investigated within 72 hours, and the standard of death was that the larvae could not crawl normally. Calculate toxicology regression equation and LC ₅₀ . The joint action method adopts the co-toxicity coefficient (CTC) method of Sun Yunpei et al.

The formula for calculating the co-toxicity coefficient is as follows:

Actual toxicity index (ATI) = (standard drug LC ₅₀ / test drug LC ₅₀ ) × 100

Theoretical toxicity index (TTI) = A agent ATI × the percentage of A in the mixture + B agent ATI × the percentage of B in the mixture

Co-toxicity coefficient (CTC) = (mixture ATI/mixture TTI) × 100

When CTC≤80, the composition exhibits antagonistic effect; when 80<CTC<120, the composition exhibits additive effect; when CTC≥120, the composition exhibits synergistic effect.

The measurement results are shown in Table 1.

Table 1 Toxicity determination of cyclopyrid, chlorfluazuron and different ratios to beet armyworm (72h)

It can be seen from Table 1 that when cycloclofen and chlorfluazuron are mixed at a ratio of 30:1 to 1:30, the co-toxicity coefficients are both greater than 120, and the composition exhibits a synergistic effect on beet armyworm. Especially when the mixing ratio of cyclopyrid and chlorfluazuron is 20:1-1:20, the composition shows obvious synergistic effect on beet armyworm.

Example 2

Determination of Toxicity of Cycloclofen, Chlorfluazuron and Mixtures with Different Proportions to Brown Planthopper

Using rice seedling dipping method. The seedlings with a height of 150 mm are divided into 10 plants/group for soaking the medicinal liquid. The same batch of mid-3rd instar nymphs was selected for testing. Soak each group of rice seedlings in the prepared medicinal solution for 10 seconds, dry them at room temperature, and put them into disposable plastic cups, one group of rice seedlings per cup, and set 3 cups for each treatment dose to repeat. Put 20 test insects of brown planthopper into each cup, seal it with plastic wrap, punch small holes on the plastic wrap with needles for ventilation, cover it with black cloth and put it in an artificial climate box at 27°C and L:D ratio of 14:10 .72-hour survey mortality. Calculate toxicology regression equation and LC ₅₀ . The joint action method adopts the co-toxicity coefficient (CTC) method of Sun Yunpei et al. The calculation method is the same as above. The measurement results are shown in Table 2.

Table 2 Toxicity determination of cycloxaprid, chlorfluazuron and different ratios to brown planthopper (72h)

It can be seen from Table 2 that when cycloclofenac and chlorfluazuron are mixed at a ratio of 30:1 to 1:30, the co-toxicity coefficients are both greater than 120, and the composition exhibits a synergistic effect on N. lugens. Especially when the mixing ratio of cycloxaprid and chlorfluazuron is 20:1-1:20, the composition shows obvious synergistic effect on brown planthopper.

The insecticidal composition of the present invention can be made into wettable powder, suspension, water dispersible granule or water emulsion. The following example illustrates.

WP formulation

Example 3

In terms of weight percentage, take cycloxaprid 17.5%, chlorfluazuron 17.5%, fatty acid polyoxyethylene ester 5%, wetting agent T3%, kaolin to make up to 100%, and the mixture is mechanically crushed to obtain epoxyclofen-containing Pyridine and chlorfluazuron wettable powder.

Example 4

In terms of weight percentage, take cycloxaprid 2%, chlorfluazuron 40%, fatty acid polyoxyethylene ester 5%, wetting agent T3%, kaolin to make up to 100%, and the mixture is mechanically pulverized to obtain epoxyclofen-containing Pyridine and chlorfluazuron wettable powder.

Suspending agent configuration

Example 5

In terms of weight percentage, take cycloclofenac 27.3%, chlorfluazuron 2.7%, sodium dodecylbenzene sulfonate 2.1%, calcium lignosulfonate 2.5%, methyl cellulose 2.5%, bentonite 3.2%, propane Triol 2%, add water to make up to 100%, and mix to obtain a suspension containing cycloclofenac and chlorfluazuron.

Example 6

In terms of weight percentage, take cycloclofenac 1.5%, chlorfluazuron 44.5%, sodium dodecylbenzene sulfonate 2.1%, calcium lignosulfonate 2.5%, methyl cellulose 2.5%, bentonite 3.2%, propane Triol 2%, add water to make up to 100%, and mix to obtain a suspension containing cycloclofenac and chlorfluazuron.

Water dispersible granules configuration

Example 7

In terms of weight percentage, take cycloclofenac 3.6%, chlorfluazuron 36.4%, sodium lauryl sulfate 3%, polyvinylpyrrolidone 5%, carboxymethyl cellulose 0.2%, pull open powder 0.3%, ammonium sulfate 8%, add kaolin to make up to 100%, and mix to obtain water-dispersible granules containing cycloclofenac and chlorfluazuron.

Example 8

In terms of weight percentage, take cycloclofenac 46.4%, chlorfluazuron 1.6%, sodium lauryl sulfate 3%, polyvinylpyrrolidone 5%, carboxymethyl cellulose 0.2%, pull open powder 0.3%, ammonium sulfate 8%, add kaolin to make up to 100%, and mix to obtain water-dispersible granules containing cycloclofenac and chlorfluazuron.

Water emulsion configuration

Example 9

In terms of weight percentage, take cycloclofenac 22.9%, chlorfluazuron 1.1%, calcium dodecylbenzenesulfonate 3.2%, cyclohexanone 10.1%, ethylene glycol 1.1%, xanthan gum 0.5%, add water to make up to 100%, mixed to obtain the aqueous emulsion containing cycloclofenac and chlorfluazuron.

The two active ingredients of the insecticidal composition of the present invention have different action mechanisms, which can delay the occurrence of insecticide resistance, reduce field dosage, effectively reduce environmental pollution and pesticide residues, and further reduce the harm to beneficial organisms. The insecticidal composition of the present invention can expand the control spectrum in application, and can control multiple pests at the same time through one spraying, thereby reducing the cost of farmers' control, and has significant economic and social benefits. The insecticidal composition of the invention has a synergistic effect on pests, can improve the control effect, and can reduce the dosage and cost of chemicals.

The above disclosures are only a few specific embodiments of the present application, but the present application is not limited thereto, and any changes conceivable by those skilled in the art shall fall within the protection scope of the present application.

Claims (6)

1. containing a Pesticidal combination for cycloxaprid and fluorine pyridine urea, it is characterized in that, described Pesticidal combination is comprised of cycloxaprid and fluorine pyridine urea, and the weight ratio of described cycloxaprid and described fluorine pyridine urea is 1:30～30:1.

2. the Pesticidal combination containing cycloxaprid and fluorine pyridine urea as claimed in claim 1, is characterized in that, the weight ratio of described cycloxaprid and described fluorine pyridine urea is 1:20～20:1.

3. the Pesticidal combination containing cycloxaprid and fluorine pyridine urea as claimed in claim 1, is characterized in that, the weight ratio of described cycloxaprid and described fluorine pyridine urea is 1:10～10:1.

4. the Pesticidal combination containing cycloxaprid and fluorine pyridine urea as claimed in claim 1, is characterized in that, the weight ratio of described cycloxaprid and described fluorine pyridine urea is 1:1.

5. the Pesticidal combination containing cycloxaprid and fluorine pyridine urea as described in any one in claim 1-4, is characterized in that, described Pesticidal combination is made wetting powder, suspending agent, water dispersible granules or aqueous emulsion.

6. the Pesticidal combination containing cycloxaprid and fluorine pyridine urea as claimed in claim 1 is for preventing and treating the application of homoptera pest and lepidoptera pest.