CN102895472B - Topical combination medicament for treating dental ulcer and preparation method thereof - Google Patents
Topical combination medicament for treating dental ulcer and preparation method thereof Download PDFInfo
- Publication number
- CN102895472B CN102895472B CN201210368234.2A CN201210368234A CN102895472B CN 102895472 B CN102895472 B CN 102895472B CN 201210368234 A CN201210368234 A CN 201210368234A CN 102895472 B CN102895472 B CN 102895472B
- Authority
- CN
- China
- Prior art keywords
- parts
- ulcer
- preparation
- medicine
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 208000025865 Ulcer Diseases 0.000 title abstract description 27
- 231100000397 ulcer Toxicity 0.000 title abstract description 27
- 230000000699 topical effect Effects 0.000 title abstract description 4
- 208000002399 aphthous stomatitis Diseases 0.000 claims abstract description 19
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 208000007117 Oral Ulcer Diseases 0.000 claims description 9
- 235000005956 Cosmos caudatus Nutrition 0.000 claims description 6
- 244000293323 Cosmos caudatus Species 0.000 claims description 6
- 239000009286 sanguis draxonis Substances 0.000 claims description 6
- 235000000177 Indigofera tinctoria Nutrition 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 229940097275 indigo Drugs 0.000 claims description 5
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 3
- 235000011837 pasties Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- 210000004877 mucosa Anatomy 0.000 abstract description 5
- 210000005178 buccal mucosa Anatomy 0.000 abstract description 3
- 241000411851 herbal medicine Species 0.000 abstract description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 abstract description 2
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 abstract description 2
- 229910021538 borax Inorganic materials 0.000 abstract description 2
- 239000004328 sodium tetraborate Substances 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241001172538 Daemonorops draco Species 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052956 cinnabar Inorganic materials 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 230000001314 paroxysmal effect Effects 0.000 abstract 1
- 239000008159 sesame oil Substances 0.000 abstract 1
- 235000011803 sesame oil Nutrition 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 description 8
- 206010010904 Convulsion Diseases 0.000 description 7
- 230000036461 convulsion Effects 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 239000003440 toxic substance Substances 0.000 description 7
- 208000037920 primary disease Diseases 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 206010015037 epilepsy Diseases 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 238000005469 granulation Methods 0.000 description 4
- 230000003179 granulation Effects 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010068319 Oropharyngeal pain Diseases 0.000 description 3
- 206010033557 Palpitations Diseases 0.000 description 3
- 201000007100 Pharyngitis Diseases 0.000 description 3
- 239000003172 expectorant agent Substances 0.000 description 3
- 230000003419 expectorant effect Effects 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010010071 Coma Diseases 0.000 description 2
- 208000006877 Insect Bites and Stings Diseases 0.000 description 2
- 206010024572 Lip ulceration Diseases 0.000 description 2
- 241000475481 Nebula Species 0.000 description 2
- 206010040943 Skin Ulcer Diseases 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 210000003026 hypopharynx Anatomy 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 230000001047 pyretic effect Effects 0.000 description 2
- 208000009146 rhinoscleroma Diseases 0.000 description 2
- 231100000019 skin ulcer Toxicity 0.000 description 2
- 208000003265 stomatitis Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 208000000412 Avitaminosis Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 206010021135 Hypovitaminosis Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 206010033078 Otitis media Diseases 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010044278 Trace element deficiency Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000007937 eating Effects 0.000 description 1
- 201000010582 ecthyma Diseases 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 210000004357 third molar Anatomy 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000005182 tip of the tongue Anatomy 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 208000030401 vitamin deficiency disease Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention belongs to the field of traditional Chinese medicine, and relates to a topical combination medicament for treating dental ulcer and a preparation method thereof. The medicament is prepared from the following raw materials in parts by weight: 14-20 parts of pearl, 2-5 parts of calculus bovis, 5-10 parts of borneol, 10-15 parts of indigo naturalis, 15-20 parts of dried alum, 10-15 parts of borax, 5-10 parts of daemonorops draco, 5-10 parts of cinnabar and 100-200 parts of sesame oil. According to the invention, the formulating prescription compatibility is appropriate and rigorous; the preparation method is unique; the adopted raw materials are Chinese herbal medicine, have no side effect, and do not bring with sequelae; moreover, the topical combination medicament for treating dental ulcer takes effect rapidly, is short in treatment course, is high in treatment rate, and is low in expense, and has unique treatment efficacy for repeated paroxysmal aphtha, root mucosa ulcer, buccal mucosa ulcer, lip mucosa ulcer and lingual mucosa ulcer.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of externally applied compound medicinal for the treatment of oral ulcer
And preparation method thereof.
Background technology
Oral ulcer, is called again " aphtha ", is the superficial ulcer occurring on oral mucosa, big or small from the grain of rice to Semen Glycines, the circular or oval of large I, and ulcer surface is recessed, hyperemia around.Ulcer has the features such as periodicity, recurrent and self limiting, is apt to occur in lip, cheek, lingual margin etc.The cause of disease and mechanism of causing a disease are still indefinite.Inducement may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in it occurs, develops.Treatment mainly be take topical therapeutic as main, and severe patient needs whole body therapeutic.Modern medicine thinks that primary disease is how relevant with the factor such as psychentonia, endocrine disturbance, malnutrition, infection, heredity, immunologic dysfunction, digestive system disease.The traditional Chinese medical science is thought the generation of primary disease, and exopathogenic factor be take pyretic toxicity as main; Endogenous cause of ill mostly is feelings will internal injury, and eating and drinking without temperance, due to chamber overstrain.
Adopt of the treatment of primary disease taken to vitamin drug treatment more both at home and abroad at present, its effect can not be satisfactory, cures the symptoms, not the disease, and treatment cycle is long, occurred the Chinese patent medicine for the treatment of primary disease on market, and effect is not ideal.
Summary of the invention
The object of this invention is to provide a kind of medicine of imitating fast, short treating period, treatment oral ulcer that cure rate is high.
For realizing object of the present invention, existing according to following technical scheme.This medicine is made by the raw material of following weight portion proportioning:
14-20 parts of Margaritas, 2-5 parts of Calculus Boviss, 5-10 parts of Borneolum Syntheticums, 10-15 parts of Indigo Naturaliss, 15-20 parts of dried Alumens, 10-15 parts of Boraxs, 5-10 parts of Sanguis Draxonis, 5-10 parts, Cinnabaris, 100-200 parts of Oleum sesami.
The fill a prescription weight proportion of best each raw material of the present invention is:
17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums, 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs, 7 parts of Sanguis Draxonis, 7 parts, Cinnabaris, 150 parts of Oleum sesami.
Preparation method of the present invention is: by prescription, take respectively above-mentioned each medicine, then grind respectively, then mix homogeneously furnishing pasty state with Oleum sesami, be.
Medicine of the present invention is according to the theory of Chinese medical discrimination, many because of long-pending in heart-fire in conjunction with primary disease, and spleen-heat is wet contains, hyperactivity of fire caused by deficiency of YIN, and fumigation is in mouth, and intenseness of heat meat is rotten, due to immunologic hypofunction.Therefore treating primary disease should heat-clearing and toxic substances removing, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, hemostasia and promoting granulation, just can receive treating both the principal and secondary aspects of a disease, be difficult for the radical cure effect of recurrence.
Side separates:
Margarita: tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, removing toxic substances and promoting granulation.Control palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, the raw cataracta of order, skin infection does not close up for a long time.
Calculus Bovis: clear away heart-fire, eliminating phlegm, has one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances.For calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
Borneolum Syntheticum: logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha.
Indigo Naturalis: nature and flavor are salty-cold, heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion.Cure mainly: epidemic febrile disease intenseness of heat, macule, spits blood, spits blood, pharyngalgia aphtha, pediatric epilepsy scared, skin ulcer is swollen, erysipelas, snake bite and insect sting.
Dried Alumen: expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.
Borax: sweet, salty, cool.External heat-clearing and toxic substances removing, detumescence, anticorrosion; Removing heat from the lung and dissipating phlegm for oral administration.For acute tonsillitis, pharyngolaryngitis, laryngopharynx swelling and pain, aphtha of the mouth and tongue, stomatitis, gingivitis, otitis media.
Sanguis Draxonis: there is promoting blood circulation to remove blood stasis, analgesic therapy, the effect of hemostasia and promoting granulation.Control continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.
Cinnabaris: clear away heart-fire relieving convulsion, the removing toxic substances of calming the nerves, for palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.
Oleum sesami: lower three warmers pyretic toxicity, the pain relieving of putting on flesh of logical intestine and small intestine, too fat to move, the granulation promoting of disappearing.
Using method of the present invention is: by appropriate directly deposited the smearing and affected part of medicine of the present invention.Administration every day 2 to 3 times, patients with mild can be cured for general 12 hours, and the general 2-7 of severe patient days can cure.
The present invention be inventor on the basis of secret prescription handed down in the family from generation to generation, in conjunction with oneself summary of clinical experience for many years, through repeatedly testing, obtain, so this medicine for external use has unique curative effect to obstinate oral ulcer.It adopts multiple Chinese herbal medicine synergy, and comprehensive measure makes the active ingredient rapid permeability focus of medicine, eliminates patient part pain, promotes ulcer spot healing.Its prescription compatibility is proper, rigorous, and preparation method is unique, adopts and is Chinese herbal medicine, without any side effects, does not stay sequela, and instant effect, short treating period, cure rate is high, expense is little.Repeated relapsing aphtha, root of the tooth mucosal ulcer, buccal mucosa ulcer, Mucosa of lip ulcer, periglottis ulcer are had to unique curative effect.
For the therapeutic effect of surperficial medicine of the present invention to oral ulcer, the inventor has carried out system clinical observation to 298 routine intractable oral cavity ulcers, and its curative effect statistical result is as follows:
Contrast before and after table 1 dental ulcer treatment
Wherein, intractable oral cavity ulcer age of onset reckling 3 years old, the maximum 70 years old, male's 116 examples, women's 182 examples.
From above-mentioned clinical statistics data, show, the present invention, to controlling the state of an illness, alleviates patient's symptom and complication successful.
the specific embodiment:
By prescription, take following medicine:
17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums, 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs, 7 parts of Sanguis Draxonis, 7 parts, Cinnabaris, 150 parts of Oleum sesami.
Preparation method of the present invention is: by prescription, take respectively above-mentioned each medicine, then grind respectively, more evenly mix with Oleum sesami, be.
model case:
Case 1, Liu, man, 30 years old, Shangqiu City people, suffered from acute stomatitis, upper lower lip ulcer, also there are two place's ulcer in Sublingual, babble at that time, tongue can not extending port outside.Go hospitalize not feel any better, the difficulty of not only having a meal, the also difficulty of speaking, is used external used medicine of the present invention 2 days upon somebody's introduction, and ulcer disappears, recovery from illness.
Case 2, Wang, man, 20 years old, Yong Cheng people from city, there is ulcer and occur scleroma in the upper lip side of taking back.Through me, introduce, once lip was bitten in the past, bad during later fashion, fail to heal completely always, within nearly one month, increase the weight of, what occur festering and touch hardens, and pain is obvious, and color is blackening gradually.I am afraid of to cancerate, and come that I go out medically, and the application of the invention external used medicine affected part every day administration 5 times, is used 2 weeks continuously, ulcer, scleroma transference cure.
Case 3, Mrs Liu, 55 years old, retired cadre, suffered from periglottis ulcer, and there is ulcer in the tip of the tongue position, once uses antibiotic therapy after one week, occurs again body part ulcer, hurt like hell, the difficulty of speaking, take food, the application of the invention external used medicine 3 days, recovery from illness.
Case 4, Li Dan, female, 3 years old, since 2000, there were several pieces of 0.5-1 centimeter of ulcer in several months oral cavity always, and hurt like hell is invalid with medical antibiotic therapy, the recovery from illness in 3 days of the application of the invention external used medicine.
Case 5, Chen man, 57 years old, people from Yucheng.Before one week, ate Caulis Sacchari sinensis and eat cut chamber buccal mucosa, ulcer occurs, ate Pianomide first quarter moon and do not heal, containing cydiodine, lose effect in addition, the recovery from illness in 5 days of the application of the invention external used medicine.
Case 6, Mrs Jia, 40 years old, Shangqiu City people, the wisdom teeth dental caries in the upper right corner goes the mucosa that burns neural latter 2 days those tooth sides to start ulcer for the first time, take Chinese patent medicine, vitamin B2, vitamin C and the Vitamains With Minerals Tablets state of an illness and do not feel any better, the recovery from illness in 7 days of the application of the invention external used medicine.
Claims (3)
1. treat an externally applied compound medicinal for oral ulcer, it is to be made by the raw material of following weight portion proportioning:
14-20 parts of Margaritas, 2-5 parts of Calculus Boviss, 5-10 parts of Borneolum Syntheticums, 10-15 parts of Indigo Naturaliss, 15-20 parts of dried Alumens, 10-15 parts of Boraxs, 5-10 parts of Sanguis Draxonis, 5-10 parts, Cinnabaris, 100-200 parts of Oleum sesami.
2. a kind of externally applied compound medicinal for the treatment of oral ulcer according to claim 1, is characterized in that the weight ratio of each raw material is: 17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums; 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs; 7 parts of Sanguis Draxonis, 7 parts, Cinnabaris, 150 parts of Oleum sesami.
3. a kind of preparation method for the treatment of the externally applied compound medicinal of oral ulcer according to claim 1 and 2, is characterized in that: by prescription, take respectively above-mentioned each medicine, then grind respectively, then mix homogeneously furnishing pasty state with Oleum sesami, be.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210368234.2A CN102895472B (en) | 2012-09-28 | 2012-09-28 | Topical combination medicament for treating dental ulcer and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210368234.2A CN102895472B (en) | 2012-09-28 | 2012-09-28 | Topical combination medicament for treating dental ulcer and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102895472A CN102895472A (en) | 2013-01-30 |
CN102895472B true CN102895472B (en) | 2014-10-01 |
Family
ID=47568158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210368234.2A Expired - Fee Related CN102895472B (en) | 2012-09-28 | 2012-09-28 | Topical combination medicament for treating dental ulcer and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102895472B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104758505A (en) * | 2015-04-02 | 2015-07-08 | 成都市飞龙水处理技术研究所青白江第一分所 | Internal medicine for treating child ptyalism and preparation method of internal medicine |
CN104758328A (en) * | 2015-04-02 | 2015-07-08 | 成都市飞龙水处理技术研究所青白江第一分所 | Powder medicine for treating severe glossitis and preparation method of powder medicine |
CN105434662A (en) * | 2015-12-31 | 2016-03-30 | 吕丽梅 | Traditional Chinese medicine preparation for treating aphthous ulcer |
CN105832942A (en) * | 2016-06-03 | 2016-08-10 | 温红卫 | Traditional Chinese medicine powder for treating aphtha and recurrent aphtha and preparation method thereof |
CN106421493A (en) * | 2016-11-30 | 2017-02-22 | 唐文龙 | Traditional Chinese medicine preparation for treating dental ulcer |
CN110339282A (en) * | 2019-07-31 | 2019-10-18 | 吉林大学 | Traditional Chinese medicine composition for treating recurrent aphthous ulcer and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1476885A (en) * | 2003-06-10 | 2004-02-25 | 王印雄 | Nianmoyankuiling for curing mucositis mucitis and its preparation |
CN102038815A (en) * | 2010-12-22 | 2011-05-04 | 于馥源 | Oral ulcer powder |
-
2012
- 2012-09-28 CN CN201210368234.2A patent/CN102895472B/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1476885A (en) * | 2003-06-10 | 2004-02-25 | 王印雄 | Nianmoyankuiling for curing mucositis mucitis and its preparation |
CN102038815A (en) * | 2010-12-22 | 2011-05-04 | 于馥源 | Oral ulcer powder |
Non-Patent Citations (2)
Title |
---|
中医药治疗复发性口疮研究进展;张杰;《河南中医学院学报》;20030131;第1卷(第1期);85-88 * |
张杰.中医药治疗复发性口疮研究进展.《河南中医学院学报》.2003,第1卷(第1期),85-88. |
Also Published As
Publication number | Publication date |
---|---|
CN102895472A (en) | 2013-01-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102895472B (en) | Topical combination medicament for treating dental ulcer and preparation method thereof | |
CN102166280B (en) | Chinese medicinal composition for preventing and treating common cold and influenza and preparation method thereof | |
CN103610885B (en) | Traditional Chinese medicine preparation for treating rash | |
CN103041030B (en) | Pharmaceutical composition for treating fever with swollen head, as well as preparation method and application thereof | |
CN104306711A (en) | Traditional Chinese medicine for treating oral ulcer | |
CN102600343B (en) | Traditional Chinese medicinal preparation for treating oral diseases and/or toothache | |
CN101390989B (en) | Traditional Chinese medicine preparation for treating recurrent oral ulcer | |
CN103393822A (en) | Drug for treating toothache and preparation method thereof | |
CN103638323B (en) | The medicine pill for the treatment of atrophic gastritis | |
CN102671058B (en) | Traditional Chinese medicine oral liquid for treatment of vomiting and preparation method thereof | |
CN101361893B (en) | A traditional Chinese medicine composition for preventing and treating osteoporosis | |
CN106511773A (en) | Traditional Chinese medicine composite for treating dental ulcer | |
CN104740443A (en) | Traditional Chinese medicine compound essential oil | |
CN104958735A (en) | Traditional Chinese medicine for treating rheumatic arthritis | |
CN103751499A (en) | Chinese medicine composition for treating dental ulcer | |
CN104189608B (en) | Traditional Chinese medicine preparation for recurrent oral ulcer and preparation method thereof | |
CN103623179B (en) | A kind of Chinese medicine composition for the treatment of snoring | |
CN103623335B (en) | A kind of Chinese medicine preparation for the treatment of rhinitis | |
CN102743516B (en) | Traditional Chinese medicine composition for treating flesh goiter | |
CN105381433A (en) | Traditional Chinese medicine oral caring and refreshing agent | |
CN106109944A (en) | A kind of Chinese medicine composition treating oral ulcer | |
CN104906352A (en) | Traditional Chinese medicine liquid for treating deficiency-fire flaring-up type infantile oral ulcer and preparation method thereof | |
CN104958653A (en) | Traditional Chinese medicine composition for treating tuberculosis | |
CN103446333A (en) | Medicament for preventing and treating odontia | |
CN104524253A (en) | Chinese medicinal composition for treatment of pregnant and lactating women toothache |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141001 Termination date: 20150928 |
|
EXPY | Termination of patent right or utility model |