CN102727392A - Emulsified composition - Google Patents

Abstract

R¹为C4～30的烃基，Z为亚甲基、次甲基或O，X¹、X²和X³为H、OH或乙酰氧基，X⁴为H、乙酰基或甘油基，r²和R³为H、OH、羟甲基或乙酰氧甲基，R⁴为C5～60的烃基，r⁵为H、C1～30的烃基；(D)阴离子表面活性剂0.00025～10质量％；(F1)水；(E)选自烷基改性聚丙烯酸类乙烯基聚合物以及烷基改性多糖类聚合物中的水溶性高分子0.001～6质量％；(F2)水。The present invention relates to a method for producing an emulsified composition comprising: mixing the following components (A), (B), (C), (D) and an aqueous phase I containing (F1), followed by emulsification and cooling step 1; then, further mixing the following component (E) and step 2 of the aqueous phase II containing (F2), (A) 0.001 to 10% by mass of a compound represented by the following general formula (1), Z ¹ is a structure having two or more hydroxyl groups on glycerol, sorbitan, sorbitol or sucrose residues, Y ¹ is an ester bond or an ether bond, R is a C14-22 hydrocarbon group, and n is 1-22 The number of 4; (B) 0.001 to 10 mass % of one or more compounds selected from C14 to 22 higher alcohols and sterols; (C) 0.001 to 15 mass % of compounds represented by general formula (2),

R ¹ is a C4-30 hydrocarbon group, Z is methylene, methine or O, X ¹ , X ² and X ³ are H, OH or acetoxy, X ⁴ is H, acetyl or glyceryl, r ² and ^R3 are H, OH, hydroxymethyl or acetoxymethyl, ^R4 is a C5-60 hydrocarbon group, ^r5 is H, a C1-30 hydrocarbon group; (D) anionic surfactant 0.00025-10% by mass ; (F1) water; (E) 0.001 to 6% by mass of water-soluble polymers selected from alkyl-modified polyacrylic vinyl polymers and alkyl-modified polysaccharide polymers; (F2) water.

Description

emulsified composition

technical field

The present invention relates to emulsified compositions.

Background technique

In the stratum corneum, the outermost layer of the skin, there are intercellular lipids that fill the stratum corneum cells and their spaces. Most of it has an α-gel structure, and for the skin, it has the function of keeping the skin soft and smooth by preventing the intrusion of substances from the outside and evaporating the water from the inside while retaining its own moisture.

In general, it is known that the reduction of intercellular lipids, especially ceramide, leads to undesirable skin conditions, and it is considered that external ceramide supplementation involves improvement of the decrease in skin function.

However, since ceramide has a high melting point and high crystallinity, it is difficult to incorporate it into external preparations and the like. Therefore, various studies have been made on stably incorporating ceramide.

For example, in Patent Document 1, it is described that an emulsified composition combining ceramide, glycerol monofatty acid ester, and higher alcohol in a specific ratio can inhibit the crystallization of ceramide and form an α-gel structure that is easy to retain moisture, thereby moisturizing The effect is high.

In addition, it has also been considered that by further combining specific sugar alcohols or 2-monosaccharides or 3-monosaccharides, the water retention capacity of the α-gel can be further improved, and the water can be left on the skin for a long time to improve the condition of the skin (Patent Document 2 , Patent Document 3).

However, although these compositions form an α-gel structure, they are difficult to apply to the skin due to their low viscosity. Therefore, even if a film with a moisturizing effect is formed, the film is fragile and cannot cover the skin uniformly, making it difficult to apply it on the skin. Exhibit sufficient moisture retention.

In addition, since the film lacks flexibility and elasticity, the skin has a characteristic roughness and roughness after application, and a good touch cannot be obtained. In addition, there was a problem that the appearance after application was not smooth, and the effect of improving the appearance of the skin could not be obtained.

prior art literature

patent documents

Patent Document 1: Japanese Patent Laid-Open No. 2007-22997

Patent Document 2: Japanese Unexamined Patent Publication No. 2011-32265

Patent Document 3: Japanese Patent Laid-Open No. 2011-32266

Contents of the invention

The present invention provides a method for producing an emulsified composition comprising: mixing the following components (A), (B), (C), and (D) and an aqueous phase I containing (F1), followed by emulsification And the operation 1 of cooling; Then, the operation 2 of further mixing the following ingredients (E) and the aqueous phase II containing (F2),

(A) 0.001 to 10% by mass of a compound represented by the following general formula (1),

(In the formula, Z ¹ represents a structure with more than 2 hydroxyl groups on glycerol, sorbitan, sorbitol or sucrose residues, Y ¹ represents an ester bond or an ether bond, R represents a carbon atom number of 14 to 22 hydrocarbon group, n represents the number of 1 to 4.)

(B) 0.001 to 10% by mass of one or more compounds selected from higher alcohols and sterols with 14 to 22 carbon atoms;

(C) 0.001 to 15% by mass of the compound represented by the general formula (2);

(wherein, R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 4 to 30 carbon atoms substituted or unsubstituted by hydroxyl, carbonyl or amino; Z represents methylene, methine or an oxygen atom; X ¹ , X ² and X ³ independently represent a hydrogen atom, a hydroxyl group or an acetoxy group; X ⁴ represent a hydrogen atom, an acetyl group or a glyceryl group, or form a bridging oxygen group together with an adjacent oxygen atom ( However, when Z is a methine group, any one of X ¹ and X ² is a hydrogen atom and the other does not exist, and X ³ does not exist when X ⁴ forms a bridging oxygen group.); R ² and R ³ independently represent Hydrogen atom, hydroxyl group, hydroxymethyl group or acetoxymethyl group; R ⁴ represents the number of carbon atoms with or without ether bond, ester bond or amide bond on the main chain substituted or unsubstituted by hydroxyl group, carbonyl group or amino group, and the number of carbon atoms is from 5 to 60 linear, branched or cyclic saturated or unsaturated hydrocarbon groups; R ⁵ represents a hydrogen atom, or represents with or without a substituent selected from hydroxyl, hydroxyalkoxy, alkoxy and acetoxy A straight-chain or branched saturated or unsaturated hydrocarbon group with a total carbon number of 1 to 30; the dotted line indicates that it may be an unsaturated bond.)

(D) 0.00025% to 10% by mass of anionic surfactant;

(F1) water;

(E) 0.001-6% by mass of water-soluble polymers selected from alkyl-modified polyacrylic vinyl polymers and alkyl-modified polysaccharide polymers;

(F2) Water.

In addition, the present invention provides an emulsified composition containing the following components (A), (B), (C), (D), (E) and (F),

(A) 0.001% to 10% by mass of glyceryl monobehenate or monocetyl glyceryl ether;

(B) 0.001% to 10% by mass of cetyl alcohol or stearyl alcohol;

(C) 0.001 to 15% by mass of ceramides represented by general formula (3) or general formula (4),

(wherein, R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 7 to 19 carbon atoms substituted or unsubstituted by hydroxyl; Z ¹ represents methylene or methine; X ⁵ , X ⁶ and X ⁷ independently represent a hydrogen atom, hydroxyl or acetoxy group; X ⁸ represents a hydrogen atom, or forms a bridging oxygen group together with an adjacent oxygen atom (however, when Z ¹ is a methine group, Any one of X ⁵ and X ⁶ is a hydrogen atom and the other does not exist; when X ⁸ forms a bridging oxygen group, X ⁷ does not exist.); R ¹² represents a hydroxymethyl or acetoxymethyl group; R ¹³ represents a hydrogen atom , or represent an alkyl group with 1 to 4 carbon atoms; R ¹⁴ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 5 to 30 carbon atoms substituted or unsubstituted by a hydroxyl group, or represents The omega end of the alkyl group is formed by ester-bonding a linear or branched saturated or unsaturated fatty acid with 8 to 22 carbon atoms substituted or unsubstituted by a hydroxyl group; the dotted line indicates that it can be unsaturated bonds.)

(wherein, R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 10-22 carbon atoms substituted or unsubstituted by hydroxyl; X ⁹ represents a hydrogen atom, acetyl group or glycerol group; R ¹⁶ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 5 to 22 carbon atoms substituted or unsubstituted by hydroxyl or amino group, or represents an ester bond at the ω terminal of the hydrocarbon group to be Hydroxyl-substituted or unsubstituted straight-chain or branched chain saturated or unsaturated fatty acids with 8 to 22 carbon atoms; R ¹⁷ represents a hydrogen atom, or represents a group formed by hydroxyl, hydroxyalkoxy, or alkoxy An alkyl group with a total carbon number of 1 to 30 substituted or unsubstituted by a group or an acetoxy group.)

(D) 0.00025% to 10% by mass of stearyl glutamate, stearyl methyl taurate or polyoxyethylene stearyl ether phosphate;

(E) (Acrylic acid/Alkyl Acrylate (C10-30)) Copolymer, (Alkyl Acrylate/Steareth Methacrylate-20) Copolymer, Laureth-13PG Hydroxyethyl Cellulose Or 0.001% to 6% by mass of sodium stearyloxy PG hydroxyethyl cellulose sulfonate;

(F) water.

The effect of the invention

Since the emulsified composition of the present invention can obtain a high-viscosity and elastic liquid, and the coating film has softness and elasticity, it can evenly cover the skin, improve the moisture retention capacity, and make the skin smooth to the touch and smooth in appearance.

Detailed ways

The present invention relates to an emulsified composition, the coating film of which has softness and elasticity, can evenly cover the skin, improves the moisture retention capacity, and makes the skin smooth to the touch and smooth in appearance.

The inventors of the present invention have found that the α-gel designed to improve the water retention ability can be obtained by combining specific water-soluble polymers, because it can obtain high viscosity and elastic liquid properties, and the coating film has flexibility and elasticity. Therefore, it is an emulsified composition that can evenly cover the skin, improve the moisture retention capacity, and make the skin feel smooth and smooth.

Component (A) used in the present invention is a compound represented by the above general formula (1).

In the formula, as the hydrocarbon group having 14 to 22 carbon atoms represented by R, it is preferably a straight-chain hydrocarbon group, for example, straight-chain alkyl groups such as myristyl, palmityl, stearyl, behenyl, etc.; palmitoyl, Oil base etc.

Examples of the compound represented by the general formula (1) include glycerol monofatty acid ester, sorbitan monofatty acid ester, sorbitan difatty acid ester, sorbitol monofatty acid ester, sorbitol Di fatty acid ester, sucrose mono fatty acid ester, glycerin monoalkyl ether, etc.

As component (A), glycerol monofatty acid ester, sorbitan monofatty acid ester, and glycerin monoalkyl ether are preferable. Among them, glyceryl monopalmitate, glyceryl monostearate, glyceryl monobehenate, sorbitan monostearate, monocetyl glyceryl ether, and monostearyl glyceryl ether are preferred. Among them, glyceryl monobehenate or monocetylglyceryl ether is more preferable from the viewpoint of improving the formation property of the lamellar film described later and the water retention property.

Component (A) can use one or more types of compounds, and it contains 0.001-10 mass % in the whole composition, Preferably it contains 0.05-7 mass %, More preferably, it contains 0.25-3 mass %. Within this range, after the emulsified composition of the present invention is applied to the skin, a lipid layer composed of components (B) to (E) described later and moisture can be formed on the skin surface during the drying process. Lamellar film with alternating layers. This result is preferable because the moisture retention capacity which can be used to retain moisture between layers is improved. It is also preferable because the feeling of use of the coating film becomes favorable.

In the component (B) used in the present invention, the higher alcohol is a higher alcohol having 14 to 22 carbon atoms, preferably 16 to 18 carbon atoms. For example, myristyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, etc. are mentioned.

Among them, cetyl alcohol and stearyl alcohol are preferred, and cetyl alcohol is more preferred.

Moreover, in a component (B), cholesterol and a phytosterol are mentioned as a sterol. Phytosterol is a general term for phytosterols such as β-sitosterol, campesterol, stigmasterol, and brassicasterol, and its composition is not limited.

Component (B) can be used in 1 or more types, and it contains 0.001-10 mass % in the whole composition, Preferably it contains 0.05-7 mass %, More preferably, it contains 0.1-3 mass %. If it is within the range, after the emulsified composition of the present invention is applied to the skin, a lipid layer composed of the above-mentioned component (A) and the following components (C) to (E) can be formed on the skin surface during drying. Lamellar membranes arranged alternately with water layers. This result is preferable because the moisture blocking property capable of retaining interlayer moisture is improved. It is also preferable because it improves the appearance of the skin after application.

The ceramides of the component (C) used in the present invention are compounds represented by the above general formula (2).

In the formula, ^R1 is a straight chain, branched or cyclic saturated or unsaturated compound having 4 to 30 carbon atoms that may be substituted by hydroxyl, carbonyl or amino, preferably 7 to 22 carbon atoms that may be substituted by hydroxyl. Saturated hydrocarbon groups or hydrogen atoms.

Z represents any one of a methylene group, a methine group or an oxygen atom.

X ¹ , X ² and X ³ each independently represent a hydrogen atom, a hydroxyl group or an acetoxy group. Preferably, 0 to 1 of X ¹ , X ² and X ³ is a hydroxyl group, and the rest are oxygen atoms. When Z is a methine group, any one of ^X1 and ^X2 is only a hydrogen atom, and the other is absent. In addition, X ⁴ is preferably a hydrogen atom or a glyceryl group.

R ² and R ³ represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group, preferably R ² is a hydrogen atom or a hydroxymethyl group, and preferably R ³ is a hydrogen atom.

R ⁴ represents a straight-chain, branched or cyclic saturated or unsaturated compound with 5 to 60 carbon atoms that may be substituted by hydroxyl, carboxyl or amino and may have an ether bond, ester bond or amide bond on the main chain. the hydrocarbon group. Preferable examples include linear, branched or cyclic saturated or unsaturated hydrocarbon groups with 5 to 35 carbon atoms that may be substituted by hydroxyl or amino groups, or bonded with an ester bond or amide at the ω position of the hydrocarbon group. A group bonded to a linear, branched or cyclic saturated or unsaturated fatty acid with 8 to 22 carbon atoms which may be substituted by a hydroxyl group. As bound fatty acid, preference is given to isostearic acid, 12-hydroxystearic acid or linoleic acid.

R ⁵ represents a hydrogen atom, or a linear or branched saturated or unsaturated group with a total carbon number of 1 to 30 that may also have a substituent selected from hydroxyl, hydroxyalkoxy, alkoxy and acetoxy the hydrocarbon group. When ^R1 is a hydrogen atom and Z is an oxygen atom, ^R5 is a hydrocarbon group with 10 to 30 carbon atoms in total. In addition, when R ¹ is a hydrocarbon group, R ⁵ is a hydrocarbon group with 1 to 8 carbon atoms in total. Among them, a hydrogen atom or a hydrocarbon group having 1 to 8 total carbon atoms which may be substituted by 1 to 3 selected from hydroxyl, hydroxyalkoxy, and alkoxy is preferable. Here, as the hydroxyalkoxy group and the alkoxy group, a group having 1 to 7 carbon atoms is preferable.

As the compound represented by the general formula (2), ceramides represented by the following general formula (3) or (4) are preferable.

(I) The compound represented by the general formula (3) may be a natural ceramide or a synthetic compound having the same structure.

(In the formula, R ¹¹ represents a straight chain, branched chain or cyclic saturated or unsaturated hydrocarbon group with 7 to 19 carbon atoms that can be substituted by a hydroxyl group; Z ¹ represents a methylene or methine group; X ⁵ , X ⁶ and X ⁷ independently represent a hydrogen atom, hydroxyl or acetoxy; X ⁸ represents a hydrogen atom, or forms a bridging oxygen group with an adjacent oxygen atom (however, when Z ¹ is a methine group, X ⁵ and any one of ^X6 is a hydrogen atom and the other does not exist; when ^X8 forms a bridging oxygen group, ^X7 does not exist.); ^R12 represents a hydroxymethyl or acetoxymethyl group; ^R13 represents a hydrogen atom, or Represents an alkyl group with 1 to 4 carbon atoms; R ¹⁴ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group with a carbon number of 5 to 30 that may be substituted by a hydroxyl group, or The omega end of the α-terminal is ester-bonded to a straight-chain or branched saturated or unsaturated fatty acid with 8 to 22 carbon atoms that can be substituted by a hydroxyl group; the dotted line indicates that it may be an unsaturated bond.)

Preferably, ^R11 is a straight-chain alkyl group with 7 to 19 carbon atoms, more preferably 13 to 15 carbon atoms, ^R14 is a straight-chain alkyl group with 9 to 27 carbon atoms that may be substituted by a hydroxyl group, or A compound in which a linear alkyl group having 9 to 27 carbon atoms is bonded to linoleic acid through an ester bond. In addition, it is preferable that ^X8 represents a hydrogen atom, or forms a bridging oxygen group together with an oxygen atom. In addition, as R ¹⁴ , tricosyl, 1-hydroxypentadecyl, 1-hydroxytricosyl, heptadecyl, 1-hydroxyundecyl, and an ester bond at the ω position are preferable. The nonacosyl group of linoleic acid.

Specific examples of natural ceramides include ceramide types 1 to 7 in which sphingosine, dihydrosphingosine, phytosphingosine, or sphingadienine (Sphingadienine) has been amidated (for example, J. Lipid Res., 24: 759 (1983) Figure 2, and J. Lipid. Res., 35: 2069 (1994) Figure 4 described porcine and human ceramides).

Furthermore, these N-alkyl forms (eg, N-methyl forms) are also included.

These ceramides may be optically active in natural type (D(-) form), optically active in non-natural type (L(+) form), or a mixture of natural and non-natural types. The relative configuration of the above-mentioned compounds may be a natural configuration, a non-natural configuration, or a mixture of these. Among them, compounds of CERAMIDE 1, CERAMIDE 2, CERAMIDE 3, CERAMIDE 5, and CERAMIDE 6II (above, INCI, 8th edition) and substances represented by the following formula are preferable.

These may be either natural extracts or synthetic compounds, and commercially available products may be used.

Commercially available products of such natural ceramides include Ceramide I, CeramideIII, CeramideIIIA, CeramideIIIB, CeramideIIIC, CeramideVI (above, Cosmo Farm Co.), Ceramide TIC-001 (Takasago Fragrance Co.), CERAMIDE II (Quest International Inc. ), DS-CeramideVI, DS-CLA-Phytoceramide, C6-Phytoceramide, DS-ceramide Y3S (DOOSAN Company), CERAMIDE 2 (Sederma Company).

(II) A pseudo-ceramide represented by the general formula (4).

(In the formula, R ¹⁵ represents a straight chain, branched chain or cyclic saturated or unsaturated hydrocarbon group or hydrogen atom with a carbon number of 10 to 22 that can be substituted by a hydroxyl group; X ⁹ represents a hydrogen atom, acetyl group or glyceryl group ; R ¹⁶ represents a straight chain, branched or cyclic saturated or unsaturated hydrocarbon group with 5 to 22 carbon atoms that can be substituted by hydroxyl or amino group, or represents an ester bond at the ω end of the hydrocarbon group that can be A group formed by a straight-chain or branched saturated or unsaturated fatty acid with 8 to 22 carbon atoms substituted by a hydroxyl group; R ¹⁷ represents a hydrogen atom, or represents a group that can be replaced by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or An alkyl group with a total carbon number of 1 to 30 substituted by an acetoxy group.)

R ¹⁶ is preferably nonyl, tridecyl, pentadecyl, undecyl in which linoleic acid is bonded to the ω position through an ester bond, pentadecyl in which linoleic acid is bonded to the ω position through an ester bond, The pentadecyl group of 12-hydroxystearic acid is bonded to the ω position by an ester bond, and the undecyl group of methyl branched isostearic acid is bonded to the ω position by an amide bond.

When R ¹⁵ is a hydrogen atom, R ¹⁷ is preferably 10 to 30 total carbon atoms that may be substituted by hydroxyl, hydroxyalkoxy, alkoxy or acetoxy, preferably 12 to 20 total carbon atoms. An alkyl group; when R ¹⁵ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group with 10 to 22 carbon atoms that can be substituted by a hydroxyl group, R ¹⁷ preferably represents a hydrogen atom, or represents that it can be An alkyl group having 1 to 8 carbon atoms in total substituted by hydroxy, hydroxyalkoxy, alkoxy or acetoxy. The hydroxyalkoxy or alkoxy group of R ¹⁷ preferably has 1 to 7 carbon atoms.

As general formula (4), preferably R ¹⁵ is hexadecyl, X ⁹ is a hydrogen atom, R ¹⁶ is pentadecyl, R ¹⁷ is a compound of hydroxyethyl; R ¹⁵ is hexadecyl, X ⁹ is Hydrogen atom, R ¹⁶ is nonyl, R ¹⁷ is hydroxyethyl; or R ¹⁵ is hexadecyl, X ⁹ is glyceryl, R ¹⁶ is tridecyl, R ¹⁷ is 3-methoxypropane The condensate-like ceramides of the ^{group ,} more preferably ^the compound ( ^N- (Hexadecyloxyhydroxypropyl)-N-Hydroxyethylhexadecanoamide).

The compound of component (C) can use 1 or more types, It contains 0.001-15 mass % in the whole composition, Preferably it contains 0.05-7 mass %, More preferably, it contains 0.5-5 mass %. If it is within the range, the above-mentioned components (A), (B) and the following components (D) to (E) can be formed on the skin surface during the drying process after the emulsified composition of the present invention is applied to the skin. A lamellar membrane consisting of lipid layers and water layers alternately arranged. As a result, interlayer moisture can be maintained. In addition, in the emulsified composition of the present invention and in the lamellar film formed after coating and drying, the component (C) was not crystallized. As a result, the component (C) can be highly permeated into the skin, which is preferable. Furthermore, it is preferable because it leads to an improvement in the appearance of the skin after application and an improvement in the feeling of use.

Examples of the anionic surfactant used in the present invention as component (D) include fatty acid salts having 12 to 24 carbon atoms such as sodium laurate, potassium palmitate, and arginine stearate; sodium lauryl sulfate , Potassium lauryl sulfate and other alkyl sulfate salts; Polyoxyethylene lauryl sulfate triethanolamine and other alkyl ether sulfate salts; N-acyl sarcosinates such as sodium lauryl sarcosinate; N-stearyl- Fatty acid amide sulfonates such as sodium N-methyl taurate and sodium N-myristoyl-N-methyl taurate; alkyl phosphates such as sodium monostearyl phosphate; sodium polyoxyethylene oleyl ether phosphate Polyoxyethylene alkyl ether phosphates, such as sodium polyoxyethylene stearyl ether phosphate; long-chain sulfosuccinates such as di-2-ethylhexyl sodium sulfosuccinate; monosodium N-lauroyl glutamate , Sodium N-Stearyl-L-Glutamate, Arginine N-Stearyl-L-Glutamate, Sodium N-Stearyl Glutamate, N-Myristoyl-L-Glutamate Sodium and other long chain N-acyl glutamate, etc.

Among them, fatty acid salts, alkyl fatty acid ester salts, alkyl ether sulfate ester salts, fatty acid amide sulfonates, alkyl phosphates, polyoxyethylene alkyl ether phosphates, polyoxyethylene alkyl ether phosphates, long Chain N-acyl glutamate.

Among them, stearoyl glutamate, stearoyl methyl taurate, polyoxyethylene stearyl ether phosphate are preferred, stearoyl glutamate and stearoyl methyl taurate are more preferred. , more preferably stearoyl glutamate.

The salt of component (D) is preferably at least one selected from sodium salts, potassium salts, basic amino acid salts, and ammonium, and is preferably selected from sodium salts and arginine from the viewpoint of expressing the viscosity of the emulsified composition. One or more types of salt.

Component (D) may be blended as an acid, or may be contained as a salt after being neutralized with an alkali. In this case, the base to neutralize the component (D) is preferably one or more selected from basic amino acids, sodium hydroxide, potassium hydroxide, triethanolamine, and calcium hydroxide, and the basic amino acids are preferably selected from arginine , lysine, and histidine, or one or more of them. The base for neutralizing the component (D) is preferably one or two selected from arginine and sodium hydroxide from the viewpoint of expressing the viscosity of the emulsified composition, and more preferably arginine from the viewpoint of usability. acid.

Component (D) can be used in 1 or more types, and it contains 0.00025-10 mass % in the whole composition, Preferably it contains 0.05-2 mass %, More preferably, it contains 0.1-1 mass %. Components (A) to (C) can be emulsified within this range. In addition, after the emulsified composition of the present invention is applied to the skin, a sheet in which lipid layers and water layers composed of components (A) to (D) and component (E) are alternately arranged can be formed on the skin surface during the drying process. Lamellar membrane. This result is preferable because interlayer moisture can be retained and is useful for improving the moisture retention capacity.

Component (E) used in the present invention is a water-soluble polymer selected from alkyl-modified polyacrylic polymers and alkyl-modified polysaccharide polymers.

Examples include alkyl acrylate copolymers, (meth)acrylic acid/alkyl (meth)acrylate copolymers, alkyl acrylate/alkyl methacrylate/polyoxyethylene stearyl ether copolymers, polysaccharide derivatives, etc.

More specifically, (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/steareth-20 methacrylate) copolymer, laureth-13PG hydroxyethyl Base cellulose, sodium stearyloxy PG hydroxyethyl cellulose sulfonate, etc.

As a commercial product, for example, ACULYN33 (The Dow Chemical Company) can be mentioned as an alkyl acrylate polymer; PEMULEN TR-1, PEMULEN TR-1, PEMULEN TR-2, Carbopol ETD2020 (above, Lubrizol Advanced Materials, Inc.), etc. In addition, examples of the alkyl acrylate/alkyl methacrylate/polyoxyethylene stearyl ether copolymer include ACULYN 22 (The Dow Chemical Company) and the like. Examples of polysaccharide derivatives include SPS-S-SA, SOFCARE EP-S (above, Kao Corporation), Natrosol Plus (Hercules-Aqualon) and the like.

One or more types of component (E) can be used, and it contains 0.001-6 mass % in the whole composition, Preferably it contains 0.05-5 mass %, More preferably, it contains 0.1-3 mass %. When it exists in this range, the storage stability of the emulsified composition of this invention can be improved. In addition, crystallization of the lipid mixture composed of components (A) to (D) can be suppressed. As a result, after application of the emulsified composition of the present invention, flexibility can be imparted to the lamellar film formed on the skin surface during the drying process. As a result, it is useful for moisture retention ability/improvement of feel/improvement of skin appearance after application, and is therefore preferable.

In the present invention, the water of the component (F) may be contained as the balance of each component, and it is preferably contained in an amount of 49 to 85% by mass, and more preferably contained in an amount of 55 to 80% by mass in the entire composition.

In the present invention, from the viewpoint of obtaining high-viscosity and elastic liquid, the mass ratio of components (A), (B), (C), (D) and (E) is preferably (E)/(( A)+(B)+(C)) = 0.0025 to 50, more preferably 0.01 to 3, particularly preferably 0.1 to 1.5. As a result, when applied to the skin, a high coating feeling can be felt and a good usability can be provided.

In addition, in order to obtain a film having flexibility and elasticity, (E)/(D)=0.025-100 is preferable, 0.14-7.5 is more preferable, and 1.2-6 is especially preferable.

In the present invention, it is more preferable to combine the respective preferred components and preferred contents of the above components.

In addition, in the emulsified composition of the present invention, preferably: component (A) is glyceryl monobehenate or monocetyl glyceryl ether, component (B) is cetyl alcohol or stearyl alcohol, component (C) It is a compound represented by the general formula (1), the component (D) is stearoyl glutamate, stearyl methyl taurate or polyoxyethylene stearyl ether phosphate, and the component (E) is ( Acrylic acid/Alkyl Acrylate (C10-30)) Copolymer, (Alkyl Acrylate/Steareth-20) Copolymer, Laureth-13PG Hydroxyethylcellulose or Stearyl Oxygen Sodium PG hydroxyethyl cellulose sulfonate, component (F) is water.

In addition, in the emulsified composition of the present invention, it is preferable that the component (A) is glyceryl monobehenate, the component (B) is cetyl alcohol, the component (C) is a compound represented by the general formula (1), and the component (D) is stearyl glutamate, component (E) is (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/steareth-20 methacrylate) Copolymer, laureth-13PG hydroxyethylcellulose or sodium stearyl PG hydroxyethylcellulose sulfonate, ingredient (F) is water.

In this invention, the lipid which forms an emulsion from components (A)-(D). If these are dried, crystallization will occur and a hard and brittle film will be formed, so that a film with high moisture retention cannot be obtained. However, by further containing the component (E), the crystallization of the lipid can be suppressed, and a large amount of water can be contained to form a lamellar soft film in which lipid layers and water layers are alternately arranged. In particular, when cetyl alcohol is used as the component (B), the flexibility of the film can be increased, and the appearance and smoothness of the skin can be improved. Furthermore, the use of the emulsified composition of the present invention for producing a skin coating agent, the use of the emulsified composition of the present invention for producing a skin moisturizing agent, and the production of a coating film-forming agent for skin can be provided Use of the emulsified composition of the present invention.

The emulsified composition of the present invention may contain oily components other than components (B) and (C). Examples include hydrocarbon oils such as liquid paraffin, squalane, and petrolatum; ether oils such as cetyl dimethyl butyl ether, ethylene glycol dioctyl ether, and glyceryl monooleyl ether; octadecyl myristate; ester oils such as isopropyl palmitate, butyl stearate, di-2-ethylhexyl adipate, neopentyl glycol dicaprate, and trioctanoin; stearic acid , behenic acid, isomyristic acid and other higher fatty acids; olive oil and other vegetable oils; dimethyl polysiloxane, cyclic dimethyl polysiloxane, methylphenyl polysiloxane, amino-modified silicone , Carboxyl-modified silicone, alcohol-modified silicone, alkyl-modified silicone, polyether-modified silicone, fluorine-modified silicone and other silicone oils; perfluoroalkyl ethyl phosphoric acid, perfluoroalkyl polyoxyethylene Phosphoric acid, perfluoropolyether, polytetrafluoroethylene and other fluorine oils, etc. These oily components are preferably contained in an amount of 0 to 20% by mass in the entire composition.

In addition, the emulsified composition of the present invention may contain active ingredients and additives commonly used in cosmetics, such as water-soluble vitamins such as ascorbic acid, niacinamide, and niacin; Extract, Tea Extract, Cucumber Extract, Clove Extract, Carrot Extract, Witch Hazel Extract, Placenta Extract, Seaweed Extract, Horse Chestnut Extract, Grapefruit Extract, Podocarpus Extract, Royal Jelly Extract , eucalyptus extract, Luo Hanbo extract and other animal and plant extracts; potassium hydroxide, sodium hydroxide, triethanolamine, sodium carbonate and other alkalis; citric acid, tartaric acid, lactic acid, phosphoric acid, succinic acid, adipic acid and other acids, etc. .

The method for producing the emulsified composition of the present invention preferably comprises: mixing the components (A) to (D) and the aqueous phase I containing a part (F1) of the component (F), followed by emulsification and cooling step 1; and then further mixing The process of component (E) and the water phase component (water phase II) containing the remainder (F2) of component (F). According to this method, an emulsion excellent in stability over a wide temperature range can be obtained by causing the polymers to interact after forming an α-gel structure, and it is preferable.

Step 1 is a step of forming an α-gel structure, and is preferably a step selected from the following four production steps of Steps 1A, 1B, 1C, and 1D. From the standpoint of manufacturability, it is preferable to select from Step 1A and Step 1C which include a step of neutralizing the unneutralized component (D) with an alkali; A step selected from step 1A and step 1B of mixing the component (D). As described above, step 1 preferably includes a step selected from step 1A, step 1B, and step 1C, more preferably includes step 1A or step 1B, and even more preferably includes step 1A.

Step 1A: is a step of obtaining a mixed component of an oil phase containing components (A), (B), (C) and an unneutralized component (D); and mixing components containing component (F) in the oil phase A portion (F1) and the aqueous phase I of the base, followed by emulsification and cooling.

Step 1B: is a step of mixing ingredients with an oil phase containing ingredients (A), (B), (C) and a salt of ingredient (D); and mixing a part of the oil phase containing ingredient (F) ( The aqueous phase I of F1) is followed by emulsification and cooling.

Step 1C: a step of obtaining a mixed component of an oil phase containing components (A), (B) and (C); and mixing unneutralized component (D) and component (F) in the oil phase A portion (F1) and the aqueous phase I of the base, followed by emulsification and cooling.

Step 1D: is a step of obtaining a mixed component of an oil phase containing components (A), (B) and (C); and mixing a salt containing component (D) and a part of component (F) in the oil phase ( The aqueous phase I of F1) is followed by emulsification and cooling.

In these methods, the water of component (F) is added and mixed as (F1) and (F2), and the mass ratio thereof is preferably (F1)/(F2)=0.1-9, more preferably 0.25-4.

The obtained emulsified composition is an α-gel (α-type crystal), and precipitation of crystals (γ-type crystal) is suppressed. The α-gel can be confirmed by X-ray structural analysis. The characteristic of the α-type structure is that it is a hexagonal crystal system, the lipophilic group is vertically oriented relative to the hydrophilic group, and a sharp diffraction peak appears near the Bragg angle of 21-23°.

In addition, the viscosity of the emulsified composition at 25° C. is preferably 10 to 8000 dPa·s, more preferably 500 to 1500 dPa·s, and still more preferably 1500 to 5000 dPa·s. The emulsified composition of the present invention can obtain a highly viscous and elastic liquid by combining the above-mentioned components.

In addition, in the present invention, the viscosity is measured at 25° C. with a B8R type rotational viscometer (spindle C or D, 5 r/min, measurement for 1 minute).

In addition, the obtained emulsified composition is an oil-in-water emulsified composition, and is preferably used as cosmetics such as lotion, emulsion, cream, and gel, or external skin preparations. Regarding the above-mentioned embodiment, the present invention further discloses the usage method and application of the following emulsified composition.

Use of an emulsified composition containing components (A), (B), (C), (D), (E) and (F) for producing a coating film-forming agent for skin.

Use of an emulsified composition containing components (A), (B), (C), (D), (E) and (F) for the production of an external preparation for skin.

The application film to the skin containing the components (A), (B), (C), (D), (E) and (F) forms an oil-in-water emulsion composition.

Example

Examples 1-10 and Comparative Examples 1-7

The oil-in-water emulsion compositions with the compositions shown in Table 1 and Table 2 were produced, and the viscosity and residual water content were measured. The lamellar structure of the film was confirmed by SAXS and the surface state was observed by SEM. In addition, the durability of moisture, the touch and appearance of the skin after application were sensory evaluated. The results are shown in Table 1 and Table 2 together.

(Manufacturing method)

Heat and mix the ingredients of the first phase at 80-90°C, add the ingredients of the second phase heated to 80-90°C under propeller stirring (300rpm), and use an emulsifying homogenizer (homomixer) at 7000rpm, 10 Minutes of emulsification while applying shear to form α-gel. After slowly cooling to 25° C., the ingredients of Phase III were added to obtain an oil-in-water emulsion composition.

(Evaluation method)

(1) Viscosity:

Measured at 25° C. with a B8R-type rotational viscometer (spindle C or D, 5 r/min, measurement for 1 minute).

(2) Residual moisture content:

1 g of the oil-in-water emulsion composition was uniformly spread to a certain thickness in a metal tray of 6×6 cm, and the mass change with respect to time was plotted at 20° C. and a constant temperature and humidity of 40%. Since the lamellar film is formed over time, the change in mass thereafter becomes extremely small. The amount of residual moisture after 24 hours with a constant mass was obtained, and the amount of moisture relative to the solid content in the formulation was obtained by the following formula. All components of components (A)-(E) are contained in solid content.

(3) Confirmation of the sheet structure by SAXS:

30分钟照射，在照相机长度(camera length)649.5mm、2θ＝0.2～5°的范围内来测定皮膜表面的状态。Spread the oil-in-water emulsion composition evenly on the artificial leather PRARE (registered trademark) at 0.001g/cm ² , let it dry for 1 day, and use Nano-viewer,

After irradiating for 30 minutes, the state of the film surface was measured in the range of camera length (camera length) 649.5 mm, 2θ=0.2 to 5°.

(4) Observation of the surface state of the film by SEM:

The oil-in-water emulsion composition was evenly spread on the artificial leather PRARE (registered trademark) at 0.001 g/cm ² , dried for 1 day, and the state of the surface of the film was observed by SEM (scanning electron microscope) at a magnification of 50 times. The results are shown by the following benchmarks.

◯: The boundary portion of Pichu and Pigou is smooth.

△: There is crimping at the boundary portion of Pichu and Pigou.

x: No film was formed.

(5) Persistence of moisture, touch (smoothness) and appearance (smooth appearance) of the skin after application:

12 panelists applied 0.4 to 0.6 g of each oil-in-water emulsion composition on the face and immediately sensory evaluated "the touch of the skin is smooth" and "the appearance of the skin is smooth", and after 10 hours after application, the sensory evaluation The "persistence of moisture" was evaluated. The results are expressed in terms of the number of panelists rated as "good".

Examples 11-29 and Comparative Examples 8-9

In the same manner as in Examples 1 to 10, oil-in-water emulsion compositions with the compositions shown in Tables 3 to 6 were produced, and the viscosity and residual water content were measured, and the lamellar structure of the film was confirmed by SAXS and by SEM. Observation of the surface state is carried out. In addition, the durability of moisture, the touch and appearance of the skin after application were evaluated. The results are shown in Table 3 to Table 6 together.

[table 3]

[Table 4]

[table 5]

[Table 6]

Embodiment 1, 30-32

An oil-in-water emulsion composition with the composition shown in Table 7 was produced in the same manner as in Examples 1 to 10, and the viscosity and residual moisture were measured, and the lamellar structure of the film was confirmed by SAXS and the surface state by SEM. observation. In addition, the durability of moisture, the touch and appearance of the skin after application were evaluated. The results are shown in Table 7 together.

[Table 7]

Examples 1 and 30 were manufactured by manufacturing process 1A, Example 31 was manufactured by manufacturing process 1C, and Example 32 was manufactured by manufacturing process 1D. In Example 1 and Example 30 produced by the production process 1A of blending the unneutralized component (D) into the oil phase, the evaluation of the smoothness of the skin touch after application was high, and the sheet that suppressed the precipitation of ceramide crystals was confirmed Layer structure, high moisturizing effect is obtained, and high viscosity is obtained.

Claims (21)

1. the manufacturing approach of an emulsification composition, wherein,

Said manufacturing approach has: following composition (A), (B), (C), (D) and the water I that contains (F1) are mixed, then emulsifying and refrigerative operation 1; Then, composition (E) below further mixing and the operation 2 that contains the water II of (F2),

(A) chemical compound 0.001～10 quality % that representes by following general formula (1),

In the formula, Z ¹Be illustrated in the structure that has the hydroxyl more than 2 on glycerol, anhydrosorbitol, Sorbitol or the sucrose residue, Y ¹Expression ester bond or ehter bond, R representes that carbon number is 14～22 alkyl, n representes 1～4 number;

(B) being selected from carbon number is 14～22 higher alcohol and 0.001～10 quality % of the chemical compound more than a kind in the sterols;

(C) chemical compound 0.001～15 quality % that representes by general formula (2),

In the formula, R ¹Expression is 4～30 straight chain, side chain or cyclic saturated or unsaturated alkyl by hydroxyl, carbonyl or amino replacement or not substituted carbon number; Z representes methylene, methine or oxygen atom; X ¹, X ²And X ³Represent hydrogen atom, hydroxyl or acetoxyl group respectively independently; X ⁴Represent hydrogen atom, acetyl group or glyceryl, or form oxo group with adjacent oxygen atom, still, X when Z is methine ¹And X ²Any one for hydrogen atom another does not exist, work as X ⁴X when forming oxo group ³Do not exist; R ²And R ³Represent hydrogen atom, hydroxyl, methylol or acetyl-o-methyl respectively independently; R ⁴Expression replaced by hydroxyl, carbonyl or amino or not substituted main chain on had or do not had ehter bond, ester bond or an amido link carbon number be 5～60 straight chain, side chain or cyclic saturated or undersaturated alkyl; R ⁵The expression hydrogen atom, or expression has or does not have the saturated or undersaturated alkyl that the substituent total carbon atom number that is selected from hydroxyl, hydroxy alkoxy base, alkoxyl and the acetoxyl group is 1～30 straight or branched; Dotted portion representes it can is unsaturated bond;

(D) anion surfactant 0.00025～10 quality %;

(F1) water;

(E) be selected from water soluble polymer 0.001～6 quality % in alkyl-modified polyacrylic polyvinyl and the alkyl-modified polysaccharide polymer;

(F2) water.

2. the manufacturing approach of emulsification composition as claimed in claim 1, wherein,

Operation 1 is following operation 1A or operation 1B,

Operation 1A has: the operation of blending constituent that obtains containing the oil phase of composition (A), (B), (C) and unneutralized composition (D); With in this oil phase, mix the water I that contains (F1) and alkali, then emulsifying and refrigerative operation,

Operation 1B has: the operation of blending constituent of oil phase that obtains containing the salt of composition (A), (B), (C) and composition (D); With in this oil phase, mix the water I that contains (F1), then emulsifying and refrigerative operation.

3. the manufacturing approach of emulsification composition as claimed in claim 1, wherein,

Operation 1 is following operation 1C or operation 1D,

Operation 1C has: the operation that obtains containing the blending constituent of composition (A), (B) and oil phase (C); With in this oil phase, mix the water I contain unneutralized composition (D), (F1) and alkali, then emulsifying and refrigerative operation,

Operation 1D has: the operation that obtains containing the blending constituent of composition (A), (B) and oil phase (C); Contain the salt of composition (D) and water I (F1) with in this oil phase, mixing, then emulsifying and refrigerative operation.

4. like the manufacturing approach of each described emulsification composition in the claim 1～3, wherein,

Composition (A), (B), (C), (D) and mass ratio (E) do, (E)/and ((A)+(B)+(C))=0.0025～50, and (E)/(D)=0.025～100.

5. like the manufacturing approach of each described emulsification composition in the claim 1～4, wherein,

Composition (A) is for being selected from the chemical compound more than a kind in fatty acid monoglyceride, anhydrosorbitol mono fatty acid ester, anhydrosorbitol di fatty acid ester, Sorbitol mono fatty acid ester, Sorbitol di fatty acid ester, sucrose monofatty acid ester and the glycerol monoalkyl ether.

6. like the manufacturing approach of each described emulsification composition in the claim 1～5, wherein,

Composition (D) is the chemical compound in 12～24 soap, alkyl sulfate salt, alkyl ether sulfate, fatty acid amide sulfonate, alkylphosphonic, polyoxyethylene alkyl ether phosphate and the long-chain N-acyl glutamate for being selected from carbon number.

7. like the manufacturing approach of each described emulsification composition in the claim 1～6, wherein,

Said emulsification composition forms α-gel structure.

8. like the manufacturing approach of each described emulsification composition in the claim 1～7, wherein,

The viscosity of said emulsification composition under 25 ℃ is 10～8000dPas.

9. like the manufacturing approach of each described emulsification composition in the claim 1～8, wherein,

Said emulsification composition contains the composition (A) of 0.05～7 quality %, the composition (B) of 0.05～7 quality %, the composition (C) of 0.05～7 quality %, the composition (D) of 0.05～2 quality %, the composition (E) of 0.05～5 quality %.

10. like the manufacturing approach of each described emulsification composition in the claim 1～9, wherein,

Composition (A), (B), (C) and mass ratio (E) do, (E)/and ((A)+(B)+(C))=0.01～3.

11. like the manufacturing approach of each described emulsification composition in the claim 2～10, wherein,

Contained alkali is a kind or 2 kinds that is selected from arginine and the sodium hydroxide among the water I.

12. an emulsification composition, wherein,

Said emulsification composition contains following composition (A), (B), (C), (D), (E) and (F),

(A) single Compritol 888 ATO or single cetyl glycerin ether 0.001～10 quality %;

(B) hexadecanol or stearyl alcohol 0.001～10 quality %;

(C) ceramide type 0.001～15 quality % that representes by general formula (2),

In the formula, R ¹Expression is 4～30 straight chain, side chain or cyclic saturated or unsaturated alkyl by hydroxyl, carbonyl or amino replacement or not substituted carbon number; Z representes methylene, methine or oxygen atom; X ¹, X ²And X ³Represent hydrogen atom, hydroxyl or acetoxyl group respectively independently; X ⁴Represent hydrogen atom, acetyl group or glyceryl, or form oxo group with adjacent oxygen atom, still, X when Z is methine ¹And X ²Any one for hydrogen atom another does not exist, work as X ⁴X when forming oxo group ³Do not exist; R ²And R ³Represent hydrogen atom, hydroxyl, methylol or acetyl-o-methyl respectively independently; R ⁴Expression replaced by hydroxyl, carbonyl or amino or not substituted main chain on had or do not had ehter bond, ester bond or an amido link carbon number be 5～60 straight chain, side chain or cyclic saturated or undersaturated alkyl; R ⁵The expression hydrogen atom, or expression has or does not have the saturated or undersaturated alkyl that the substituent total carbon atom number that is selected from hydroxyl, hydroxy alkoxy base, alkoxyl and the acetoxyl group is 1～30 straight or branched; Dotted portion representes it can is unsaturated bond;

(D) stearyl glutamate, Glu, stearyl methyl tauride or polyoxyethylene stearyl base ether phosphate 0.00025～10 quality %;

(E) (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/methacrylic acid stearyl alcohol polyethers-20) copolymer, laureth-13PG hydroxyethyl-cellulose or stearic oxygen base PG hydroxyethyl-cellulose sodium sulfonate 0.001～6 quality %;

(F) water.

13. emulsification composition as claimed in claim 12, wherein,

Composition (A) is single Compritol 888 ATO;

Composition (B) is a hexadecanol;

Composition (C) is the ceramide type by general formula (3) or general formula (4) expression,

In the formula, R ¹¹Expression is 7～19 straight chain, side chain or cyclic saturated or undersaturated alkyl by hydroxyl replacement or not substituted carbon number; Z ¹Expression methylene or methine; X ⁵, X ⁶And X ⁷Represent hydrogen atom, hydroxyl or acetoxyl group respectively independently; X ⁸Represent hydrogen atom, or form oxo group, still, work as Z with adjacent oxygen atom ¹X during for methine ⁵And X ⁶Any one for hydrogen atom another does not exist, work as X ⁸X when forming oxo group ⁷Do not exist; R ¹²Expression methylol or acetyl-o-methyl; R ¹³The expression hydrogen atom, or the expression carbon number is 1～4 alkyl; R ¹⁴Expression is replaced by hydroxyl or not substituted carbon number is 5～30 straight chain, side chain or cyclic saturated or undersaturated alkyl, or is illustrated on the ω end of this alkyl with ester bond and combines to be replaced or not substituted carbon number is the group that the saturated or undersaturated fatty acid of 8～22 straight or branched forms by hydroxyl; Dotted portion representes it can is unsaturated bond,

In the formula, R ¹⁵Expression is 10～22 straight chain, side chain or cyclic saturated or undersaturated alkyl by hydroxyl replacement or not substituted carbon number; X ⁹Expression hydrogen atom, acetyl group or glyceryl; R ¹⁶Expression is replaced by hydroxyl or amino or not substituted carbon number is 5～22 straight chain, side chain or cyclic saturated or undersaturated alkyl, or is illustrated on the ω end of this alkyl with ester bond and combines to be replaced or not substituted carbon number is the group that the saturated or undersaturated fatty acid of 8～22 straight or branched forms by hydroxyl; R ¹⁷The expression hydrogen atom, or expression is 1～30 alkyl by hydroxyl, hydroxy alkoxy base, alkoxyl or acetoxyl group replacement or not substituted total carbon atom number;

Composition (D) is the stearyl glutamate, Glu;

Composition (E) is (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/methacrylic acid stearyl alcohol polyethers-20) copolymer, laureth-13PG hydroxyethyl-cellulose or stearic oxygen base PG hydroxyethyl-cellulose sodium sulfonate;

Composition (F) is a water.

14. like claim 12 or 13 described emulsification compositions, wherein,

Composition (A), (B), (C), (D) and mass ratio (E) do, (E)/and ((A)+(B)+(C))=0.0025～50 and (E)/(D)=0.025～100.

15. like each described emulsification composition in the claim 12～14, wherein,

Said emulsification composition forms α-gel structure.

16. like each described emulsification composition in the claim 12～15, wherein,

The viscosity of said emulsification composition under 25 ℃ is 10～8000dPas.

17. like each described emulsification composition in the claim 12～16, wherein,

Said emulsification composition contains the composition (A) of 0.05～7 quality %, the composition (B) of 0.05～7 quality %, the composition (C) of 0.05～7 quality %, the composition (D) of 0.05～2 quality %, the composition (E) of 0.05～5 quality %.

18. like each described emulsification composition in the claim 12～17, wherein,

Composition (A), (B), (C) and mass ratio (E) do, (E)/and ((A)+(B)+(C))=0.01～3.

19. each described emulsification composition is in the purposes that is used for making the skin smears in the claim 12～18.

20. each described emulsification composition is in the purposes that is used for making the moisture of skin retention agent in the claim 12～18.

21. each described emulsification composition is being used for making the purposes that the coated film of skin is formed agent in the claim 12～18.