CN102670717B - Tortoise shell traditional Chinese medicine oral liquid for relieving rheumatoid arthritis and preparation method thereof - Google Patents

Abstract

The invention discloses a tortoise shell traditional Chinese medicine oral liquid for relieving rheumatoid arthritis, which is prepared from the following raw material medicines in parts by weight: 100 pieces of alangium chinense pursh 200 pieces, 100 pieces of divaricate saposhnikovia root soaking 200 pieces, 250 pieces of tortoise shell soaking 350 pieces, 100 pieces of cassia twig soaking 200 pieces, 100 pieces of twotooth achyranthes root soaking 200 pieces and 100 pieces of incised notopterygium rhizome soaking 200 pieces.

Description

Oral liquid of tortoiseshell traditional Chinese medicine for alleviating rheumatoid arthritis and its preparation method

technical field

The invention belongs to the field of traditional Chinese medicines, and in particular relates to a tortoise shell traditional Chinese medicine oral liquid for relieving rheumatoid arthritis and a preparation method thereof.

Background technique

Rheumatoid arthritis (RA) is a systemic immune disease characterized by chronic polyarthritis, which not only invades joints and tendons, but also affects various organs. 10 years after the onset of the disease, the disability rate is 60%, which is one of the main causes of disability, and there is no specific therapy at present. There are various clinical treatment methods, and the general principle of remission is to control inflammation, relieve symptoms, delay disease progression, maintain joint function and prevent deformity. Traditional Chinese medicine is used to relieve rheumatoid arthritis because of its small side effects and good curative effect, so it is very popular among people.

Contents of the invention

The object of the present invention is to provide a tortoise shell traditional Chinese medicine oral liquid for alleviating rheumatoid arthritis with few side effects and good curative effect and a preparation method thereof.

To achieve the above object, the present invention is achieved through the following technical solutions:

The tortoiseshell traditional Chinese medicine oral liquid for alleviating rheumatoid arthritis is made from the following raw materials in parts by weight:

100-200 parts of star anise maple, 100-200 parts of Fangfeng, 250-350 parts of tortoise shell, 100-200 parts of cassia twig, 100-200 parts of Achyranthes bidentata, 100-200 parts of notopterygium.

The tortoiseshell traditional Chinese medicine oral liquid for alleviating rheumatoid arthritis is made from the following raw materials in parts by weight:

150 parts of star anise maple, 150 parts of Fangfeng, 300 parts of tortoise shell, 150 parts of cassia twig, 150 parts of Achyranthes bidentata, 150 parts of Qianghuo.

The described tortoiseshell traditional Chinese medicine oral liquid for alleviating rheumatoid arthritis and its preparation method comprise the following steps:

Take 150 parts of star anise maple, 150 parts of Fangfeng, 300 parts of tortoise shell, 150 parts of cassia twig, 150 parts of Achyranthes bidentata, 150 parts of notopterygium, decoct twice with water, each time the amount of water is 8-10 times the weight of the medicinal materials, decoct Boil twice, each time for 1-2 hours, filter, concentrate the filtrate into a clear paste with a relative density of 1.10-1.25 measured at 60-65°C, add ethanol until the ethanol content is 60%, and stir well , stand still, filter, take the filtrate to recover ethanol, concentrate it into an extract containing 65-67% of solid weight, add 20% of sucrose, 12% of refined honey, and 1-3% of preservatives, pot the stock solution, and sterilize it by irradiation , package the finished product, and make it into an oral liquid.

Taking method: Take it once a day in the morning, noon and evening, with a dose of 20ml at a time, and 30 days as a course of treatment. After taking the medicine, it will take effect in 5 days at most, and it will be cured after 3-6 courses of treatment. The characteristics of the traditional Chinese medicine oral liquid are that it can make patients recover well, has little toxic and side effects, can treat both symptoms and root causes, strengthen the body without stagnation of pathogens, and eliminate pathogens without harming the body. It has no recurrence and low cost, and is worthy of clinical popularization and application.

Among the raw materials of traditional Chinese medicines used in the present invention, star anise maple: pungent, slightly warm, poisonous, entering the heart, liver meridian, expelling wind and dehumidification, relaxing tendons and activating collaterals, dissipating stasis and relieving pain; Fangfeng: pungent, sweet, slightly warm, returning to bladder, liver, spleen Meridian, expelling wind-dampness and arthralgia, expelling wind and cold, relieving spasm and diarrhea; tortoise shell (tortoise shell): sweet, salty, cold, returning to liver, kidney, heart meridian, nourishing yin, reducing heat and subsiding yang, relieving wind, nourishing kidney and strengthening bones, solidifying Meridian to stop bleeding, nourish blood and invigorate the heart; Guizhi: pungent, sweet, and warm, return to the heart, lung, and bladder meridians, sweat and relieve muscles, warm and unblock the meridians, help yang transform qi; Achyranthes bidentata: bitter, sour, flat, return to the liver and kidney Meridian, promoting blood circulation, tonifying liver and kidney, strengthening bones and muscles, diuresis and dredging stranguria, igniting fire (blood) descending; notopterygium: pungent, bitter, warm, returning to bladder and kidney meridian, dispelling cold and expelling wind, eliminating dampness and relieving pain; traditional Chinese medicine theory believes: Insufficient righteousness, deficiency of liver and kidney, weakness of muscles and bones, lack of interstitial joints, and weak defense are the internal factors causing rheumatoid arthritis; the external cause is the attack of wind, cold, damp and heat. Sick for a long time easily enters the network, and causes blood stasis to block the network, so wind, damp, heat, cold, stasis of blood, deficiency are its main pathological factors. The disease persists for a long time, and it is easy to cause mixed cold and heat, and the disease of both deficiency and excess. In the acute stage, pathogenic excess is the main factor and positive deficiency is the main principle. In the remission stage, eliminating pathogenic factors and strengthening vital energy is the treatment principle. This prescription is based on expelling wind and dampness, clearing heat and dispelling cold, nourishing liver and kidney, strengthening muscles and bones, diuresis, reducing swelling, dredging collaterals and relieving pain. , all medicines share the merit of expelling wind and removing dampness, clearing heat and reducing swelling, dispelling cold and dredging collaterals, benefiting liver and kidney, eliminating numbness and relieving pain altogether. The oral liquid of the invention can rapidly relieve the arthralgia and swelling caused by rheumatoid arthritis, and is specially cured by special medicine and has remarkable curative effect. Note: Pregnant women are prohibited.

Detailed ways

Example 1:

Raw materials: 150 parts of star anise maple, 150 parts of Fangfeng, 300 parts of tortoise shell, 150 parts of cassia twig, 150 parts of Achyranthes bidentata, 150 parts of notopterygium.

Preparation method: Take 150 parts of star anise maple, 150 parts of Fangfeng, 300 parts of tortoise shell, 150 parts of cassia twig, 150 parts of Achyranthes bidentata, 150 parts of notopterygium, decoct twice with water, each time the water consumption is 8-10 times the weight of the medicinal materials Decoct twice, each time for 1-2 hours, filter, and concentrate the filtrate into a clear paste with a relative density of 1.10-1.25 measured at 60-65°C, add ethanol until the ethanol content is 60% , stir well, leave standstill, filter, take the filtrate to recover ethanol, concentrate into an extractum containing 65-67% of solid weight, add 20% of sucrose, 12% of refined honey, and 1-3% of preservatives, the stock solution is potted, radiated According to sterilization, the finished product is packaged, and made into oral liquid, to get final product.

Example 2:

Raw materials: 200 parts of star anise maple, 200 parts of Fangfeng, 350 parts of tortoise shell, 200 parts of cassia twig, 200 parts of Achyranthes bidentata, 200 parts of notopterygium.

Preparation method: Take 200 parts of star anise maple, 200 parts of Fangfeng, 350 parts of tortoise shell, 200 parts of cassia twig, 200 parts of Achyranthes bidentata, 200 parts of notopterygium, decoct twice with water, each time the water consumption is 8-10 times the weight of the medicinal materials amount, decocted twice, each time for 1-2 hours, filtered, and the filtrate was concentrated into a clear paste with a relative density of 1.10-1.25 measured at 60-65 ° C, and ethanol was added to make the ethanol content 60%. Stir well, stand still, filter, take the filtrate to recover ethanol, concentrate it into an extract containing 65-67% of solid weight, add 20% of sucrose, 12% of refined honey, and 1-3% of preservatives, potting the original solution, and irradiating Sterilize, package the finished product, and make it into an oral liquid.

Example 3:

Raw materials: 100 parts of star anise maple, 100 parts of Fangfeng, 250 parts of tortoise shell, 100 parts of cassia twig, 100 parts of Achyranthes bidentata, 100 parts of notopterygium.

Preparation method: take 100 parts of star anise maple, 100 parts of Fangfeng, 250 parts of tortoise shell, 100 parts of cassia twig, 100 parts of Achyranthes bidentata, 100 parts of notopterygium, decoct twice with water, each time the water consumption is 8-10 times the weight of the medicinal materials amount, decocted twice, each time for 1-2 hours, filtered, and the filtrate was concentrated into a clear paste with a relative density of 1.10-1.25 measured at 60-65 ° C, and ethanol was added to make the ethanol content 60%. Stir well, stand still, filter, take the filtrate to recover ethanol, concentrate it into an extract containing 65-67% of solid weight, add 20% of sucrose, 12% of refined honey, and 1-3% of preservatives, potting the original solution, and irradiating Sterilize, package the finished product, and make it into an oral liquid.

Example 4:

1. Clinical trial: 70 patients with rheumatoid arthritis were clinically observed and relieved, aged 35 to 68 years, with a course of disease ranging from 1 year to 10 years.

2. Therapeutic method: take the Chinese medicine oral liquid made by the embodiment of the present invention 1, take it once every morning, noon and evening, once a dosage is 20ml, and 30 days is a course for the treatment of.

3. Treatment standard:

Recently cured: the joint pain and swelling disappeared, and the mobility impairment and the grip strength of both hands returned to normal.

Significant effect: joint pain and swelling disappeared, mobility impairment and recovery of grip strength of both hands were significantly improved.

Effective: the self-evaluation of the patient was improved, and the symptoms of the affected joints were relieved.

Ineffective: no change in symptoms before and after treatment.

4. Treatment effect: 70 clinical cases, 40 cases were cured recently, 20 cases were markedly effective, 5 cases were effective, and 5 cases were ineffective, the total effective rate was 92.8%.

Example 5:

Typical case: Lu Mou, female, 32 years old, suffered from rheumatoid arthritis for 2 years, took the traditional Chinese medicine oral liquid prepared in Example 1 of the present invention, took it once a day in the morning, noon and evening, and the dosage was 20ml for 30 days For one course of treatment, three courses of treatment are cured.

Embodiment 6:

Typical case: Han, female, 50 years old, suffered from rheumatoid arthritis for 8 years, took the traditional Chinese medicine oral liquid prepared in the embodiment of the present invention 1, and took it once a day in the morning, noon and evening, and the dosage at one time was 20ml.

Embodiment 7:

Typical case: Sun, man, 69 years old, suffered from rheumatoid arthritis for 10 years, took the traditional Chinese medicine oral liquid made by the embodiment of the present invention 1, and took it once every morning, noon and evening, once a dose of 20ml, 30 days. One course of treatment, four courses of treatment are cured.

Claims (1)

1. a preparation method for alleviating rheumatoid arthritis tortoise shell Chinese medicine oral liquid, is characterized in that: comprise the following steps: Take 100 parts of star anise maple, 100 parts of Fangfeng, 250 parts of tortoise shell, 100 parts of cassia twig, 100 parts of Achyranthes bidentata, 100 parts of notopterygium, decoct twice with water, each time the amount of water is 8-10 times the weight of the medicinal materials, decoct Boil twice, each time for 1-2 hours, filter, the filtrate is concentrated into a clear paste with a relative density of 1.10-1.25 measured at 60-65 ° C, add ethanol until the ethanol content is 60%, stir well, let stand, Filtrate, take the filtrate to recover ethanol, concentrate it into an extract containing 65-67% of solid weight, add 20% of sucrose, 12% of refined honey, and 1-3% of preservatives, potting the original solution, sterilizing by irradiation, and packaging the finished product. Made into oral liquid, that is, too.