CN102429954A - Processing method of motherwort - Google Patents

Abstract

The invention relates to a processing method of motherwort, which comprises the steps of taking motherwort, cutting into sections, adding yellow wine accounting for 30% of the weight of the motherwort, soaking the motherwort in a closed container for 1 hour, draining off the yellow wine, reserving redundant yellow wine for later use, cooking the soaked motherwort in a pressure cooker at the set temperature of 120 ℃ for 2 hours under the pressure of 0.2MPa, taking out the motherwort, drying the motherwort in a hot air circulating oven at the temperature of 60 ℃ for 5 hours, taking out the motherwort after drying, adding redundant yellow wine in the soaking step, putting the motherwort in the closed container to be moistened till the yellow wine is completely absorbed by medicinal materials, taking the motherwort moistened and completely absorbed by the yellow wine, drying the motherwort in the hot air circulating oven at the temperature of 60 ℃ for 5 hours, and drying the processed motherwort to obtain the finished product with the good pain relieving effect.

Description

A kind of concocting method of Herba Leonuri

Technical field

The present invention relates to a kind of concocting method of Herba Leonuri, belong to medical technical field.

Background technology

Herba Leonuri is the herb of labiate Herba Leonuri.1 year or biennial herb, bloom summer.Be born in hill wasteland, ridge, meadow etc.Whole nation most of areas all has distribution.Summer riotous growth flower do not pluck during standard-sized sheet.Edible effect: acrid in the mouth is bitter, cool.Invigorate blood circulation, dispel silt, regulating menstruation, water disappears.The treatment menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, rushes down blood, the carbuncle skin infection at hematuria.Wine Herba Leonuri concocting method is: get the Herba Leonuri section, spray quantitative yellow wine and mix thoroughly, moistening slightly, treat that wine is exhausted after, put in the parch container, fry to little with slow fire and do, take out, cool (100 jin of every Herba Leonuris are with 15 jin of yellow wine).Analgesia generally use wine product, and its curative effect of discovery instability in clinical use is unfavorable for that Herba Leonuri uses and develop in pharmaceuticals industry.

Summary of the invention

In view of the deficiency of prior art, the object of the present invention is to provide a kind of concocting method of Herba Leonuri.

The objective of the invention is to realize like this: a kind of concocting method of Herba Leonuri, it is following to concoct step:

A. get Herba Leonuri, add the yellow wine of Herba Leonuri weight 30%, put in the hermetic container and soaked 1 hour, drain, unnecessary yellow wine is subsequent use;

The Herba Leonuri that b. will soak is placed on steaming and decocting in the pressure cooker, and design temperature is 120 ℃, and the time is 2 hours, and pressure is 0.2MPa;

C. take out the Herba Leonuri of HTHP steaming and decocting, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, oven dry;

D. the Herba Leonuri after will drying adds unnecessary yellow wine in a step immersion process, puts moistening in the hermetic container, till being exhausted by medical material to yellow wine;

E. get the Herba Leonuri that is exhausted by the yellow wine moistening, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, and oven dry promptly gets the Herba Leonuri processed product.

Prior art is compared, and the Herba Leonuri analgesic effect that the present invention makes is better, helps large-scale production and application, compared with prior art has outstanding substantive distinguishing features and obvious improvement.

The specific embodiment

Below form through Test Example foregoing of the present invention is remake further detailed description; But should this be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following instance, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.

Embodiment 1: the preparation of Herba Leonuri processed product:

A. get Herba Leonuri 100g, add the 30g yellow wine, put in the hermetic container and soaked 1 hour, drain, unnecessary yellow wine is subsequent use;

The Herba Leonuri that b. will soak is placed on steaming and decocting in the pressure cooker, and design temperature is 120 ℃, and the time is 2 hours, and pressure is 0.2MPa;

C. take out the Herba Leonuri of HTHP steaming and decocting, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, oven dry;

D. the Herba Leonuri after will drying adds unnecessary yellow wine in a step immersion process, puts moistening in the hermetic container, till being exhausted by medical material to yellow wine;

E. get the Herba Leonuri that is exhausted by the yellow wine moistening, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, and oven dry promptly gets the Herba Leonuri processed product.

Embodiment 2: different Herba Leonuri processed product analgesic activity researchs

1 materials and methods

1.1 animal cleaning level ICR mice, body weight 18-22g, male and female half and half provide licence by Yangzhou University's medical college Experimental Animal Center: SCXK (Soviet Union) 2004-0006.

1.2 reagent: yellow wine (Guyuelongshan Shaoxing Wine Co Ltd, Zhejiang, 20090303)

1.3 medicine

The common processed product of Herba Leonuri: get Herba Leonuri 100g, add the 15g yellow wine, mix thoroughly, moistening slightly, treat that yellow wine is exhausted after, fry to little and do, the cold of drying in the air, the common processed product of Herba Leonuri.

Herba Leonuri processed product of the present invention: press the foregoing description 1 preparation and get.

1.4 method

30 healthy ICR mices are divided into 3 groups at random, and 10 every group, male and female half and half are divided into model group, the common processed product of Herba Leonuri, Herba Leonuri processed product group of the present invention.Every afternoon, model group was irritated stomach pure water 10ml/kg, and the common processed product of Herba Leonuri, Herba Leonuri processed product group dosage of the present invention are 8.6g crude drug/kg, irritated the long-pending 0.1ml/10g of body of stomach, continuous 10 days.After the last administration, each organize in the morning every day lumbar injection 0.5% glacial acetic acid 0.1ml/ only, that observes mice in 10 minutes after the injection immediately turns round the body number of times.See table 1.

Analgesia percentage rate (%)=(model group writhing response number of times one administration group writhing response number of times)/model group writhing response number of times x 100%

Table 1 the present invention to mice acetic acid cause the pain turn round body effect (x ± s, n=10)

Compare * * P＜0.01 with the common processed product group of Herba Leonuri

The result shows in the table 1, and the acetic acid 0.lrnl/ of mouse peritoneal injection 0.5% only can cause mouse peritoneal pain, writhing response occurs.After the administration, Herba Leonuri processed product analgesic activity of the present invention obviously is better than the common processed product of Herba Leonuri.

Claims (1)

1. the concocting method of a Herba Leonuri, it is following to it is characterized in that concocting step:

A. get Herba Leonuri, cutting adds the yellow wine of Herba Leonuri weight 30%, puts in the hermetic container and soaks 1 hour, drains, and unnecessary yellow wine is subsequent use;

The Herba Leonuri that b. will soak is placed on steaming and decocting in the pressure cooker, and design temperature is 120 ℃, and the time is 2 hours, and pressure is 0.2MPa;

C. take out the Herba Leonuri of HTHP steaming and decocting, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, oven dry;

D. the Herba Leonuri after will drying adds unnecessary yellow wine in a step immersion process, puts moistening in the hermetic container, till being exhausted by medical material to yellow wine;

E. get the Herba Leonuri that is exhausted by the yellow wine moistening, in heated-air circulation oven, dry, temperature is 60 ℃, and the time is 5 hours, and oven dry promptly gets the Herba Leonuri processed product.