CN102369940A - Bactericidal composite containing fluopicolide and Zhongshengmycin - Google Patents
Bactericidal composite containing fluopicolide and Zhongshengmycin Download PDFInfo
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- CN102369940A CN102369940A CN2011103380066A CN201110338006A CN102369940A CN 102369940 A CN102369940 A CN 102369940A CN 2011103380066 A CN2011103380066 A CN 2011103380066A CN 201110338006 A CN201110338006 A CN 201110338006A CN 102369940 A CN102369940 A CN 102369940A
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- Prior art keywords
- bacterium amine
- pyrrole bacterium
- rhzomorph
- fluorine
- middle living
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 24
- 239000002131 composite material Substances 0.000 title abstract description 25
- 239000005782 Fluopicolide Substances 0.000 title abstract description 4
- VMFXMTJCTSYHCF-HHQUSWFZSA-N [(2r,3r,4s,5r)-5-(hexylamino)-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate Chemical compound CCCCCCN[C@@H]1[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)OC1\N=C\1NC(C(=O)NCC2O)C2N/1 VMFXMTJCTSYHCF-HHQUSWFZSA-N 0.000 title abstract description 4
- GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 title abstract description 4
- 239000000839 emulsion Substances 0.000 claims abstract description 26
- 239000000375 suspending agent Substances 0.000 claims abstract description 18
- 230000001580 bacterial effect Effects 0.000 claims abstract description 16
- 241000233679 Peronosporaceae Species 0.000 claims abstract description 14
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 13
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 13
- 241000918585 Pythium aphanidermatum Species 0.000 claims abstract 2
- 241000894006 Bacteria Species 0.000 claims description 114
- 150000001412 amines Chemical class 0.000 claims description 109
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical compound [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 claims description 95
- 239000000203 mixture Substances 0.000 claims description 51
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims description 32
- 201000010099 disease Diseases 0.000 claims description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 19
- 239000000843 powder Substances 0.000 claims description 17
- 238000009736 wetting Methods 0.000 claims description 17
- 229910052731 fluorine Inorganic materials 0.000 claims description 15
- 239000011737 fluorine Substances 0.000 claims description 15
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 14
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- 238000009472 formulation Methods 0.000 claims description 3
- 241000209504 Poaceae Species 0.000 claims description 2
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
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- 229940124561 microbicide Drugs 0.000 claims 1
- 239000002855 microbicide agent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 23
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- 239000003814 drug Substances 0.000 description 33
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- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 8
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- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 2
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- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
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- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 2
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- 230000001018 virulence Effects 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- BQSPOPBPQURHDF-QVYRLLROSA-N (4s)-2-amino-5-[(1r)-2-amino-1-hydroxyethyl]-4,5-dihydro-1h-imidazole-4-carboxylic acid Chemical compound NC[C@@H](O)C1NC(N)=N[C@@H]1C(O)=O BQSPOPBPQURHDF-QVYRLLROSA-N 0.000 description 1
- LYCAIKOWRPUZTN-NMQOAUCRSA-N 1,2-dideuteriooxyethane Chemical compound [2H]OCCO[2H] LYCAIKOWRPUZTN-NMQOAUCRSA-N 0.000 description 1
- VIESAWGOYVNHLV-UHFFFAOYSA-N 1,3-dihydropyrrol-2-one Chemical class O=C1CC=CN1 VIESAWGOYVNHLV-UHFFFAOYSA-N 0.000 description 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 1
- YBNQFFSHDBUNAA-UHFFFAOYSA-N 2,3,4-trifluoro-1h-pyrrole Chemical compound FC1=CNC(F)=C1F YBNQFFSHDBUNAA-UHFFFAOYSA-N 0.000 description 1
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 1
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 1
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- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 240000003377 Shepherdia canadensis Species 0.000 description 1
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- BQSPOPBPQURHDF-UHFFFAOYSA-N Streptolidine Natural products NCC(O)C1NC(N)=NC1C(O)=O BQSPOPBPQURHDF-UHFFFAOYSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 241000589652 Xanthomonas oryzae Species 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a bactericidal composite containing fluopicolide and Zhongshengmycin which serve as active components, wherein the weight percentage of fluopicolide to Zhongshengmycin is 1%-60%:1%-60%. Auxiliaries are added to the active components to be prepared into wettable powder, water dispersible granules, a suspending agent, emulsion in water, suspending emulsion and microemulsion. The bactericidal composite provided by the invention can be used for preventing and controlling downy mildew, blight, anthracnose, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, sheath blight, Alternaria leaf spot, damping off, and has the advantages of wide bactericidal spectrum, small dosage, rainwash resistance and obvisou synergism.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of bactericidal composition on crop pest of a kind of fluorine-containing pyrrole bacterium amine and middle living rhzomorph.
Technical background
Fluorine pyrrole bacterium amine, English name: fluopicolide, molecular formula: C
14H
8Cl
3F
3N
2O, chemical name: 2,6-two chloro-N-[(3-chloro-5-trifluoromethyl-2-pyridine radicals) methyl] benzamide.Fluorine pyrrole bacterium amine protectiveness is good, permeability is strong, and the true guiding principle fungus diseases of oomycetes is had higher biologically active, has good control efficiency.Can conduct from leaves of plants basal orientation blade tip direction.To protecting blade not receive infection process after the young shoot processing.Can also distribute from root along the plant xylem to whole strain crop, but can not conduct along phloem.
It is efficient protection and its unique mixture prescription of result of treatment source of preventing and treating the Oomycete vegetable disease.This product has good system's conductivity and stronger thin layer penetration power, and each main form of pathogen is all had good inhibitory effect, can provide comprehensively and lasting protection for young leaves, stem, stem tuber, young fruit.Since medicament can be through the blade face fast Absorption, so resistance of rainwater washing against, for vegetables diseases prevention in rainy season provides reliable guarantee.
Middle rhzomorph (zhongshengmycin), the molecular formula: C of giving birth to
19H
34O
8N
8, chemical name: the amino L-lysine-2 of 1-N glucoside base streptolidine base-2-deoxidation gulose amine.Middle living rhzomorph is a N-glucoside antibiotic, and its has a broad antifungal spectrum can resisting gram-positive, negative bacteria, mycobacterium, saccharomycete and filamentous fungi.Especially to crops pathogenic bacteria such as dish Bacteria erwinia, the angular leaf spot of cucumber bacterium, Xanthomonas oryzae, fusarium graminearum etc. all have tangible antibacterial activity.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor research, find fluorine pyrrole bacterium amine and middle living rhzomorph is composite each other, good synergistic effect is arranged within the specific limits, and relevant composite about fluorine pyrrole bacterium amine and middle living rhzomorph, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect is good fluorine-containing pyrrole bacterium amine and the bactericidal composition of middle living rhzomorph.
The present invention realizes through following technical scheme:
The bactericidal composition of a kind of fluorine-containing pyrrole bacterium amine and middle living rhzomorph is characterized in that: the percentage by weight of effective active composition fluorine pyrrole bacterium amine and middle living rhzomorph is 1%～60%: 1%～60%.
The bactericidal composition of described fluorine-containing pyrrole bacterium amine and middle living rhzomorph is characterized in that: the percentage by weight of fluorine pyrrole bacterium amine and middle living rhzomorph is 2%～40%: 2%～40%.
The bactericidal composition of described fluorine-containing pyrrole bacterium amine and middle living rhzomorph is characterized in that: the percentage by weight of fluorine pyrrole bacterium amine and middle living rhzomorph is 5%～30%: 5%～30%.
The bactericidal composition of described fluorine-containing pyrrole bacterium amine and middle living rhzomorph is processed wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
The bactericidal composition of described fluorine-containing pyrrole bacterium amine and middle living rhzomorph, the disease that is used to prevent and treat grass family class crop, vegetables, fruit tree.
Described bactericidal composition is mainly used in plant diseases such as preventing and treating downy mildew, eqpidemic disease, anthracnose, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, banded sclerotial blight, spot defoliation, damping off.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 0.5%～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～70% active substance by weight, preferably is 5%～50%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5%～30% of a total formulation weight amount, and surplus is a liquid diluent.
The surfactant that bactericidal composition of the present invention is selected for use is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the antifoaming agent one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
When processing wetting powder, composition comprises following constituent content: fluorine pyrrole bacterium amine 1～60%, middle living rhzomorph 1～60%, dispersant 5～10%, wetting agent 2～10%, filler surplus.
The former medicine of fluorine pyrrole bacterium amine, the former medicine of middle living rhzomorph, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When processing water dispersible granules, composition comprises following constituent content: fluorine pyrrole bacterium amine 1～60%, middle living rhzomorph 1～60%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler surplus.
The former medicine of fluorine pyrrole bacterium amine, the former medicine of middle living rhzomorph, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that article are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
When processing suspending agent, composition comprises following constituent content: fluorine pyrrole bacterium amine 1～40%, middle living rhzomorph 1～40%, dispersant 2～10%; Wetting agent 2～10%, antifoaming agent 0.1～1%, thickener 0.1～2%; Antifreeze 0.1～8%, stabilizing agent 0.05～3%, deionized water adds to 100%.
Dispersant, wetting agent, antifoaming agent, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear; Add the former medicine of fluorine pyrrole bacterium amine, the former medicine of middle living rhzomorph; Ball milling is 2～3 hours in ball mill; Make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is processed suspension emulsion: fluorine pyrrole bacterium amine 1%～40%, middle living rhzomorph 1%～40%, emulsifier 2%～10%, dispersant 2%～10%, antifoaming agent 0.1%～2%, thickener 0.1%～2%, antifreeze 0.1%～8%, stabilizing agent 0.05%～3%, water add to 100%.
Dispersant, antifoaming agent, thickener, antifreeze, stabilizing agent in the above-mentioned prescription are mixed through high speed shear; Add the former medicine of fluorine pyrrole bacterium amine; Ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes fluorine pyrrole bacterium amine suspending agent; Then with the former medicine of middle living rhzomorph, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
When processing aqueous emulsion, composition comprises following constituent content: fluorine pyrrole bacterium amine 1%～40%, middle living rhzomorph 1%～40%, solvent 2%～10%, emulsifier 2%～12%; Dispersant 2%～10%, co-emulsifier 0.2%～5%, antifreeze 0.1%～8%, antifoaming agent 0.1%～2%, thickener 0.1%～2%, deionized water adds to 100%.
Be dissolved into even oil phase with having former medicine, solvent, emulsifier, co-emulsifier to add together in the above-mentioned prescription, making.With deionized water, dispersant, antifreeze,, antifoaming agent, thickener mix, and becomes the homogeneous water, under high-speed stirred, water slowly splashed into oil phase, processes the finely disseminated aqueous emulsion product of the present composition.
When processing microemulsion, composition comprises following constituent content: fluorine pyrrole bacterium amine 1%～40%, middle living rhzomorph 1%～40%, emulsifier 5%～15%, and solvent 2%～10%, antifreeze 5%～10%, stabilizing agent 0.5%～3%, deionized water adds to 100%.
Above-mentioned prescription Central Plains medicine, solvent, emulsifier are added in the mother liquor modulation kettle; Make even oil phase; Deionized water, antifreeze etc. is mixed injection product modulation kettle,, mix and process the transparent or semitransparent microemulsion product of the present composition through high-speed stirred.
Beneficial effect of the present invention: (1) present composition effective active composition fluorine pyrrole bacterium amine and middle living rhzomorph belong to the bactericide of different effects mechanism, and each other composite have a good synergistic effect; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) organic solvent usage amount of the present invention is little, is difficult for producing poisoning, is convenient to transportation and storage; (4) present composition has enlarged fungicidal spectrum, and crop downy mildew, eqpidemic disease, anthracnose, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, banded sclerotial blight, spot defoliation, damping off are all had special efficacy.
Embodiment
The present invention is explained further that the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application implementation example one
Give birth to the rhzomorph wetting powder in the instance 110% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 5%, middle living rhzomorph 5%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, spaonin powder 5%, kaolin add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in the 10% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph wetting powder in the instance 224% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 20%, middle living rhzomorph 4%, polycarboxylate 7%, sldium lauryl sulfate 4%, bentonite add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in the 24% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph wetting powder in the instance 361% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 60%, middle living rhzomorph 1%, polyoxyethylene carboxylate 6%, Nekal BX 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in the 61% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph water dispersible granules in the instance 418% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 15%, middle living rhzomorph 3%, lignosulfonates 8%, silkworm excrement 6%, urea 2.5%, kaolin add to 100%, give birth to the rhzomorph water dispersible granules in mixed the 18% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph water dispersible granules in the instance 515% fluorine pyrrole bacterium amine
The phonetic formaldehyde condensation products sulphate of fluorine pyrrole bacterium amine 10%, middle living rhzomorph 5%, alkylphenol-polyethenoxy 7%, lauryl sodium sulfate 4%, aluminium chloride 3%, attapulgite add to 100%, give birth to the rhzomorph water dispersible granules in mixed the 15% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph water dispersible granules in the instance 641% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 1%, middle living rhzomorph 40%, naphthalene sulfonic acid-formaldehyde condensation product 8%, neopelex 5%, bentonite add to 100%, give birth to the rhzomorph water dispersible granules in mixed the 41% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph suspending agent in the instance 78% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 5%, middle living rhzomorph 3%, alkylnaphthalene sulfonate 8%, wetting and penetrating agent F 4%, C
8～10Aliphatic alcohols 0.2%, hydroxyethylcellulose 0.9%, ethylene glycol 2.8%, deionized water add to 100%, and mixed getting given birth to the rhzomorph suspending agent in the 8% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph suspending agent in the instance 812% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 9%, middle living rhzomorph 3%, aliphatic amine polyoxyethylene are phonetic 6%, lauryl sodium sulfate 5%, silicone compound 0.4%, xanthans 1.1%, diethylene glycol (DEG) 2%, deionized water add to 100%, give birth to the rhzomorph suspending agent in mixed the 12% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph suspending agent in the instance 925% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 15%, middle living rhzomorph 10%, ester polyoxyethylene are phonetic 7%, neopelex 3%, silicone oil 0.3%, Magnesiumaluminumsilicate 0.8%, polyethylene glycol 2.5%, deionized water add to 100%, give birth to the rhzomorph suspending agent in mixed the 25% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph suspension emulsion in the instance 106% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 3%, middle living rhzomorph 3%, lignosulfonates 7%, wetting and penetrating agent F 4%, methylcellulose 0.9%, tween series 5%, propane diols 2%, silicone 0.2%, water add to 100%, in mixed 6% fluorine pyrrole bacterium amine, give birth to the rhzomorph suspension emulsion.
Give birth to the rhzomorph suspension emulsion in the instance 118% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 6%, middle living rhzomorph 2%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 8%, Nekal BX 3%, xanthans 1.1%, phenethyl phenol polyoxy ethyl polypropylene-base ether 6%, triethylene glycol 2.5%, silicone oil 0.1%, water add to 100%, in mixed 8% fluorine pyrrole bacterium amine, give birth to the rhzomorph suspension emulsion.
Give birth to the rhzomorph suspension emulsion in the instance 1220% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 16%, middle living rhzomorph 4%, lignosulfonates 5%; Soapberry powder 4%, sodium phosphate trimer 0.8%, polyethylene glycol 2.3%, silicone compound 0.4%, AEO 8%, water add to 100%, and mixed getting given birth to the rhzomorph suspension emulsion in the 20% fluorine pyrrole bacterium amine.
Give birth to rhzomorph alcohol aqueous emulsion in the instance 132% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 1%, middle living rhzomorph 1%, toluene 6%, ethyl acetate 3%, sorbitan monostearate 5%, diethylene glycol (DEG) 2.1%, silicone oil 0.2%, deionized water adds to 100%, gives birth to rhzomorph alcohol aqueous emulsion in mixed the 2% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph aqueous emulsion in the instance 1412% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 2%, middle living rhzomorph 10%, cyclohexanone 6%, butanols 3%, alkyl benzene calcium sulfonate 7%, glycerine 2.5%, silicone 0.5%, deionized water adds to 100%, in mixed 12% fluorine pyrrole bacterium amine, gives birth to the rhzomorph aqueous emulsion.
Give birth to the rhzomorph aqueous emulsion in the instance 1516% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 10%, middle living rhzomorph 6%, 3-methyl cyclohexanol ketenes 8%, acetone 2%, ethylene oxide-propylene oxide block copolymer 6%, triethylene glycol 3%, C
8～10Aliphatic alcohols 0.1%, deionized water adds to 100%, gives birth to the rhzomorph aqueous emulsion in the 16% fluorine pyrrole bacterium amine through mixed getting.
Give birth to the rhzomorph microemulsion in the instance 168% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 6%, middle living rhzomorph 2%, vegetable oil 4%, butyl ether 3%, alkylphenol-formaldehyde resin polyoxy ethyl ether 9%, ethylene glycol 2%, silicone compound 0.3%, deionized water adds to 100%, gives birth to the rhzomorph microemulsion in mixed the 8% fluorine pyrrole bacterium amine.
Give birth to the rhzomorph microemulsion in the instance 1712% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 10%, middle living rhzomorph 2%, N-pyrrolidones 6%, EGME 4%, castor oil polyoxyethylene ether 7%, ethylene glycol 2.5%, silicone 0.4%, deionized water adds to 100%, in mixed 12% fluorine pyrrole bacterium amine, gives birth to the rhzomorph microemulsion.
Give birth to the rhzomorph microemulsion in the instance 1828% fluorine pyrrole bacterium amine
Fluorine pyrrole bacterium amine 20%, middle living rhzomorph 8%, cyclohexanone 5%, toluene 4%, NPE phosphate 6%, propane diols 3%, silicone oil 0.2%, deionized water adds to 100%, in mixed 28% fluorine pyrrole bacterium amine, gives birth to the rhzomorph microemulsion.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Fluorine pyrrole bacterium amine and middle living rhzomorph are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was confirmed in prerun, medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is following:
Wherein: a, b are respectively active component fluorine pyrrole bacterium amine and middle living rhzomorph shared ratio in combination;
A is a fluorine pyrrole bacterium amine;
B is middle living rhzomorph.
Practice example two:
Fluorine pyrrole bacterium amine and middle living rhzomorph are composite to the cucumber downy mildew Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of confirming fluorine pyrrole bacterium amine, the former medicine of middle living rhzomorph and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 fluorine pyrrole bacterium amine, the composite toxicity test analysis of results table of middle living rhzomorph to cucumber downy mildew
Can know that by table 1 fluorine pyrrole bacterium amine, middle living rhzomorph are to the EC of cucumber downy mildew
50Be respectively 1.86mg/L and 1.45mg/L.Fluorine pyrrole bacterium amine and middle living rhzomorph proportioning were at 60: 1 to 1: 60 o'clock; Synergy ratio SR is all greater than 1.5; Explaining that fluorine pyrrole bacterium amine and middle living rhzomorph were mixed in the scope at 60: 1 to 1: 60 all shows synergistic effect; Especially when the two proportioning during at 5: 1 to 1: 5; Synergistic effect is more obviously outstanding, synergy ratio SR maximum when fluorine pyrrole bacterium amine and middle living rhzomorph percentage by weight are 1: 1 wherein, and synergistic effect is the most obvious; Test is found; When the proportioning of fluorine pyrrole bacterium amine and middle living rhzomorph during at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 to banded sclerotial blight, vegetables downy mildew, eqpidemic disease, soft rot, bacterial angular leaf spot, bacterial wilt, fruit tree ring spot, spot defoliation, anthracnose, synergistic effect is obvious, synergy ratio is all greater than 1.5.
Application implementation example trifluoro pyrrole bacterium amine and the middle living rhzomorph and the composite control apple anthracnose test of pesticide effectiveness thereof
This EE is the Weinan City Baishui County in Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, gives birth to rhzomorph wetting powder (commercial) in the contrast medicament 687.5 grams per liter fluorine pyrrole bacterium amine propamocarb suspending agents (commercial), 3%.
The investigation apple anthracnose state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 2 fluorine pyrrole bacterium amine, middle living rhzomorph and the composite control apple anthracnose test of pesticide effectiveness thereof
Can find out that by table 2 can effectively prevent and treat apple anthracnose after fluorine pyrrole bacterium amine and middle living rhzomorph are composite, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects; Simultaneously to banded sclerotial blight, vegetables downy mildew, eqpidemic disease, soft rot, bacterial wilt, bacterial angular leaf spot; The preventive effect of the common diseases of crop such as fruit tree ring spot, spot defoliation, shot hole is all more than 95%; Be superior to single agent preventive effect, synergistic effect is obvious.
Application implementation example tetrafluoro pyrrole bacterium amine and the middle living rhzomorph and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This EE is the Weinan City Linwei District in Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, gives birth to rhzomorph wetting powder (commercial) in the contrast medicament 687.5 grams per liter fluorine pyrrole bacterium amine propamocarb suspending agents (commercial), 3%.
The investigation cucumber downy mildew state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 3 fluorine pyrrole bacterium amine, middle living rhzomorph and the composite control cucumber downy mildew test of pesticide effectiveness thereof
Can find out by table 3, fluorine pyrrole bacterium amine with in sick rhzomorph can effectively prevent and treat cucumber downy mildew after composite, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.The target crop is had no adverse effects in the scope of medication in test, simultaneously to the preventive effect of diseases such as eqpidemic disease, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, anthracnose, banded sclerotial blight all more than 95%, preventive effect is superior to contrasting medicament, synergistic effect is obvious.
Application implementation example five fluorine pyrrole bacterium amine and the middle living rhzomorph and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof
This EE is the Yulin City Jingbian County in Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, gives birth to rhzomorph wetting powder (commercial) in the contrast medicament 687.5 grams per liter fluorine pyrrole bacterium amine propamocarb suspending agents (commercial), 3%.
The investigation potato late blight state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 10 days once is total to dispenser 3 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the third time.Experimental result is as follows:
Table 4 fluorine pyrrole bacterium amine, middle living rhzomorph and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof
Can find out that by table 4 can effectively prevent and treat potato late blight after fluorine pyrrole bacterium amine and middle living rhzomorph are composite, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.The target crop is had no adverse effects in the scope of medication in test, simultaneously to the preventive effect of diseases such as downy mildew, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, anthracnose, banded sclerotial blight all more than 95%, preventive effect is superior to contrasting medicament, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition of fluorine-containing pyrrole bacterium amine and middle living rhzomorph, it is characterized in that: the percentage by weight of effective active composition fluorine pyrrole bacterium amine and middle living rhzomorph is 1%～60%: 1%～60%.
2. the bactericidal composition of a kind of fluorine-containing pyrrole bacterium amine according to claim 1 and middle living rhzomorph is characterized in that: the percentage by weight of fluorine pyrrole bacterium amine and middle living rhzomorph is 2%～40%: 2%～40%.
3. the bactericidal composition of a kind of fluorine-containing pyrrole bacterium amine according to claim 2 and middle living rhzomorph is characterized in that: the percentage by weight of fluorine pyrrole bacterium amine and middle living rhzomorph is 5%～30%: 5%～30%.
4. the bactericidal composition of a kind of fluorine-containing pyrrole bacterium amine according to claim 1 and middle living rhzomorph is characterized in that: the formulation of microbicide compositions is selected from: wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
5. the bactericidal composition of a kind of fluorine-containing pyrrole bacterium amine according to claim 1 and middle living rhzomorph is used to prevent and treat the application of disease on grass family class crop, vegetables, the fruit tree.
6. application according to claim 5 is characterized in that: described disease comprises downy mildew, eqpidemic disease, anthracnose, ring spot, soft rot, bacterial wilt, bacterial angular leaf spot, banded sclerotial blight, spot defoliation, damping off.
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Application publication date: 20120314 |