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CN102349510A - Composite disinfectant for livestock and poultry and using method - Google Patents

Composite disinfectant for livestock and poultry and using method Download PDF

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Publication number
CN102349510A
CN102349510A CN2011102317402A CN201110231740A CN102349510A CN 102349510 A CN102349510 A CN 102349510A CN 2011102317402 A CN2011102317402 A CN 2011102317402A CN 201110231740 A CN201110231740 A CN 201110231740A CN 102349510 A CN102349510 A CN 102349510A
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China
Prior art keywords
disinfectant
livestock
poultry
composite disinfectant
lactic acid
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CN2011102317402A
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Inventor
邹新华
户陆女
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GANZHOU 8V BIOLOGICAL TECHNOLOGY CO LTD
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GANZHOU 8V BIOLOGICAL TECHNOLOGY CO LTD
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Priority to CN2011102317402A priority Critical patent/CN102349510A/en
Publication of CN102349510A publication Critical patent/CN102349510A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

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Abstract

The invention relates to an animal disinfectant, especially to a composite disinfectant for livestock and poultry and a using method thereof. 1000ml composite disinfectant at Ph of 2.7-3.2 contains, by weight, 5-15% of ditetradecyl methyl betaine, 5.4-17.06 % of lactic acid of 0.1mol/L, 0.01-1% of fatty alcohol polyoxyethylene ether and 66.94-89.59 % of water. The using method is to dilute according to the proportion of V/V being 1: 600 until the pH value is 5.5-6.0 after the dilution and disinfect animals by air spraying. The composite disinfectant can be used to kill more aftosa virus and pseudorabies virus than air disinfectants for animals in the market with the killing rate being raised by over 10% and the highest rate being more than 20%.

Description

A kind of livestock and poultry are with composite disinfectant and method for using
Technical field
The present invention relates to a kind of animal disinfectant, particularly a kind of livestock and poultry are with composite disinfectant and method for using.
Background technology
In the livestock and poultry cultivation process, spray, spray, sterilization such as drinking-water, with disinfecting air, colony house, drinking-water and livestock and poultry epidermis, specifically be divided into sky hurdle house and drive the thing sterilization.Drive propagation that the thing sterilization can suppress cause of disease in the air, reduce dirt content, (the specific bacteriogenic toxin that suppresses airborne endotoxin; Can be attached on the dust granules, this toxin has tangible influence to health and the production capacity of swinery) influence that animal is caused.Drive the thing disinfectant require can not be poisonous, excitant arranged, peculiar smell is arranged, be corrosive, can not be used for aerosol type as strong acid, highly basic, phenols preparation etc. and drive the thing sterilization.
Surfactant is not only to contain hydrophobic grouping but also contain hydrophilic radical, nonirritant, free from extraneous odour, non-corrosive amphoteric compound in the molecule.Cationic surface active agent and amphoteric ionic surfactant in the surfactant (showing as cationic under the acid condition) are adsorbable in the thalline surface because of having positive charge; And through changing the permeability of bacterium endochylema film; The thalline material is exosmosed; Hinder its metabolism and make bacterial death, and be used in the disinfectant products.Surfactant type disinfectant Disinfection Effect is subjected to the influence of hydrophobic grouping in the disinfectant structure (alkyl chain) carbon chain lengths, when carbon number in the alkyl chain is less than 10 or greater than 16 the time, disinfectant is little to the lethality of bacterium; And when carbon number 14, the antimicrbial power of disinfectant is maximum.And similar quaternary ammonium salt disinfectant, the toxicity that contains short alkyl chain is than big than two alkyl of the toxicity of big, the monoalkyl of long alkyl chain.
Used in the market drive thing disinfectant is the single disinfectant of cationic surfactant (amine salt type, quaternary), and representative products has " hundred poisonings ", " adding iodine hundred poisonings ", and its hydrophobic grouping alkyl chain carbon atomicity is 10.This type disinfectant Disinfection Effect usually is subjected to the weak points such as influence of environment pH value, organic matter, water quality etc.Like two ten alkyl-dimethyl ammonium chlorides (a kind of cation bi-quaternary ammonium salt) when pH=9 and the pH=3 colibacillary bactericidal effect is differed 3-10 doubly.
Two myristyl methyl betaine are a kind of hydrophobic grouping of two long-chains and zwitterionic surfactants of a hydrophilic radical of containing, and hydrophobic grouping alkyl chain carbon atomicity is 14, chemistry two myristyl methyl amine second lactones by name, and molecular formula is (C 14H 29) 2-NCH 3CH 2COO, isoelectric point is 6.5~7.5.Owing to contain the hydrophobic grouping of two long-chains in the molecule, and carbon number is 14 of optimum germicidal effect, so it has stronger bactericidal effect.Two myristyl methyl betaine are by two myristyl tertiary amines and chloroacetate reaction preparation.
Lactic acid, chemical name are α-Qiang Jibingsuan, and molecular formula is CH 3CHOHCOOH, molecular weight are 90.08, colourless or light yellow viscous liquid, and odorlessness can mix arbitrarily with water, pure and mild glycerine.Pharmaceutically as disinfection preservative, its steam is used for indoor sterilization.The organic acid disinfectant is at present commonly used has Peracetic acid, citric acid, lactic acid, glutaric acid etc., and wherein minimum with the lactic acid excitant, safety is the strongest.In the present invention, lactic acid directly plays disinfective action on the one hand, guarantee also that on the other hand thimerosal stoste and dilution are acid, thereby assurance double ion surfactant is normally brought into play effect.
Summary of the invention
The present invention seeks in order to fill up livestock and poultry blankly and overcome the weak point that existing cationic surface active agent exists, and provide a kind of livestock and poultry with composite disinfectant and method for using with double ion type surfactant disinfectant.
Technical scheme of the present invention is: a kind of livestock and poultry are used composite disinfectant, comprise two myristyl methyl betaine, lactic acid, fatty alcohol-polyoxyethylene ether, water; And among the 1000ml, contain two myristyl methyl betaine mass ratio 5-15%, 0.1mol/L lactic acid mass ratio 5.4-17.06%, fatty alcohol-polyoxyethylene ether mass ratio 0.01-1%, quality is than 66.94-89.59%, and its pH is 2.7-3.2.
Described livestock and poultry are with the method for using of composite disinfectant, and dilution ratio V/V is 1: 600, and the pH value is 5.5-6.0 after the dilution, drive thing air-atomizing sterilization.
Fatty alcohol-polyoxyethylene ether is a non-ionic surface active agent, and it has synergistic function with two myristyl methyl betaine, and because of its to acid, alkali high stability, so have stabilizer function concurrently.
Discover that the anti-organic matter ability of zwitterionic surfactant, anti-pH ability all are better than cationic surfactant, and toxicity is littler.The present invention selects for use has sterilizing ability preferably; Less hemolytic; High anti-organic matter ability; Little pH influence; Two long-chain amphoteric ionic surfactants of extremely low toxicity, high advantages such as permeability (two myristyl methyl betaine) are composite with organic acid (lactic acid); Form a kind of cationic surfactant disinfectant that both had, the composite disinfectant of weak acid disinfectant effect is arranged again, and this disinfectant has remedied the weak point of single cationic surfactant disinfectant.
Two myristyl methyl betaine of the double ion surfactant that bactericidal effect is good, excitant is little except selecting for use in the present invention, the external environment influence is little and the lactic acid; The most important is that thimerosal stoste of the present invention and dilution are acidity in addition, and the pH of dilution is 5.5-6.0.This weakly acidic thimerosal; Normally bring into play the effect except that guaranteeing the double ion surfactant; All right acidifying air; Kill acid nonfast pathogen in the air (like aphthovirus, Pseudorabies virus); And form the protective layer of one deck weakly acidic condition in the pig surface; Improve self epidemic prevention ability, reduce infection rate.
The good effect that the present invention has:
1, the two myristyl methyl betaine of the zwitterionic surfactant that the present invention is lower with toxicity first, excitant is littler are used for disinfectant for animals, have remedied the blank in the disinfectant industry.
2, the present invention uses disinfectant with zwitterionic surfactant and organic acid compatibility as livestock and poultry first, and it is not enough to have replenished single use organic acid disinfectant, reduces cost simultaneously, raises the efficiency.
Confirm through comparative trial that 3, disinfectant of the present invention is better than existing air sanitizer for animals on the market killing all to show on aphthovirus, Pseudorabies virus, the total bacterial population, killing rate improves more than 10%, is up to more than 20%.
4, disinfectant acidity of the present invention is low, and excitant is little, and is safe, and forms a kind of weak acid environment, suppresses pathogen, improves livestock and poultry self-defense ability.
Embodiment
Embodiment 1:
Disinfectant prescription of the present invention: in the 1000ml thimerosal, contain two myristyl methyl betaine mass ratioes 5%, contain 0.1mol/L lactic acid mass ratio 17.06%, fatty pure APEO synergist mass ratio is 0.01%, and quality is than 77.93%, and the pH value is 2.7.
Compound method: measure the two myristyl methyl betaine solution (content is 30%) of 167ml, take by weighing the 10g fatty alcohol-polyoxyethylene ether, water is settled to 981.04ml, adds 0.1mol/L lactic acid 18.96ml again, and last mixing gets final product.
Method for using: air-atomizing sterilization (can drive the thing sterilization), dilution ratio V/V is 1: 600, dilution back pH value is 5.5.Comparative trial: at two pig houses that area is identical, service life is identical; Use like product on amphion composite disinfectant of the present invention and the market " hundred poisonings " respectively; Dilution ratio V/V is 1: 600, and the thimerosal volume is 6000ml, is 30min action time.Respectively the forward and backward once appearance of respectively adopting of sterilizing.The nutrient agar of the used diameter 9cm of air sampling, the concrete method of sampling is got 3 points for adopting dull and stereotyped natural sedimentation on house ground, hurdle face diagonal, and every dot spacing 1m, the flat board of will sampling place overhead 1m eminence, open dull and stereotyped lid and expose the 5min sampling.To adopt excellent flat board and in incubator, cultivate 24-48h, record flat-plate bacterial colony number calculates average total number of bacteria and sees table 1.
Table 1 the present invention and " hundred poisonings " disinfectant Disinfection Effect contrast
Figure BDA0000083109680000031
Can know from table 1 result: the present invention is to bacterium average kill ratio=1-260/840.67=69.07% the test pig house air; And " hundred poisoning " disinfectant is to bacterium average kill ratio=1-389.33/857.33=54.59% in the test pig house air, and double ion type surfactant composite disinfectant killing rate has improved 14.48% than " hundred poisonings ".
Embodiment 2:
Disinfectant prescription of the present invention: in the 1000ml thimerosal, contain two myristyl methyl betaine mass ratioes 10%, contain 0.1mol/L lactic acid mass ratio 5.4%, fatty pure APEO synergist mass ratio is 0.05%, and quality is than 84.55%, and the pH value is 3.2.
Compound method: measure the two myristyl methyl betaine solution (content is 30%) of 334ml, take by weighing the 50g fatty alcohol-polyoxyethylene ether, water is settled to 994ml, adds 0.1mol/L lactic acid 6ml again, and last mixing gets final product.
Method for using: air-atomizing sterilization (can drive the thing sterilization), dilution ratio V/V is 1: 600, dilution back pH value is 6.0.
Comparative trial: at two pig houses that area is identical, service life is identical; Use like product on amphoteric ion type composite disinfectant of the present invention and the market " hundred poisonings " respectively; Dilution ratio V/V is 1: 600, and the thimerosal volume is 6000ml, is 30min action time.Respectively the forward and backward once appearance of respectively adopting of sterilizing.The nutrient agar of the used diameter 9cm of air sampling, the concrete method of sampling is got 3 points for adopting dull and stereotyped natural sedimentation on house ground, hurdle face diagonal, and every dot spacing 1m, the flat board of will sampling place overhead 1m eminence, open dull and stereotyped lid and expose the 5min sampling.To adopt excellent flat board and in incubator, cultivate 24-48h, record flat-plate bacterial colony number calculates average total number of bacteria and sees table 2.
Table 2 the present invention and " hundred poisonings " disinfectant Disinfection Effect contrast
Figure BDA0000083109680000041
Can know from table 2 result: the present invention is to bacterium average kill ratio=1-287/812.33=64.67% the test pig house air; And " hundred poisoning " disinfectant is to bacterium average kill ratio=1-385/847.33=54.56% in the test pig house air, and double ion type surfactant composite disinfectant killing rate has improved 10.11% than " hundred poisonings ".
Embodiment 3:
Disinfectant prescription of the present invention: in the 1000ml thimerosal, contain two myristyl methyl betaine mass ratioes 15%, contain 0.1mol/L lactic acid mass ratio 5.4%, fatty pure APEO synergist mass ratio is 1%, and quality is than 78.6%, and the pH value is 3.2.
Compound method: measure the two myristyl methyl betaine solution (content is 30%) of 501ml, take by weighing the 100g fatty alcohol-polyoxyethylene ether, water is settled to 994ml, adds 0.1mol/L lactic acid 6ml again, and last mixing gets final product.
Method for using: air-atomizing sterilization (can drive the thing sterilization), dilution ratio V/V is 1: 600, dilution back pH value is 6.0.
Comparative trial: at two pig houses that area is identical, service life is identical; Use like product on amphoteric ion type composite disinfectant of the present invention and the market " hundred poisonings " respectively; Dilution ratio V/V is 1: 600, and the thimerosal volume is 6000ml, is 30min action time.Respectively the forward and backward once appearance of respectively adopting of sterilizing.The nutrient agar of the used diameter 9cm of air sampling, the concrete method of sampling is got 3 points for adopting dull and stereotyped natural sedimentation on house ground, hurdle face diagonal, and every dot spacing 1m, the flat board of will sampling place overhead 1m eminence, open dull and stereotyped lid and expose the 5min sampling.To adopt excellent flat board and in incubator, cultivate 24-48h, record flat-plate bacterial colony number calculates average total number of bacteria and sees table 3.
Can know from table 3 result: the present invention is to bacterium average kill ratio=1-216.33/864.67=74.98% the test pig house air; And " hundred poisoning " disinfectant is to bacterium average kill ratio=1-399/859=53.55% in the test pig house air, and double ion type surfactant composite disinfectant killing rate has improved 21.43% than " hundred poisonings ".
Table 3 the present invention and " hundred poisonings " disinfectant Disinfection Effect contrast
Figure BDA0000083109680000051

Claims (3)

1. livestock and poultry are used composite disinfectant, it is characterized in that: comprise two myristyl methyl betaine, lactic acid, fatty alcohol-polyoxyethylene ether, water; And among the 1000ml, contain two myristyl methyl betaine mass ratio 5-15%, 0.1mol/L lactic acid mass ratio 5.4-17.06%, fatty alcohol-polyoxyethylene ether mass ratio 0.01-1%, quality compares 66.94-89.59%.
2. a kind of livestock and poultry according to claim 1 are used composite disinfectant, it is characterized in that: its pH is 2.7-3.2.
3. the described a kind of livestock and poultry of claim 1 is characterized in that with the method for using of composite disinfectant: dilution ratio V/V is 1: 600, and the pH value is 5.5-6.0 after the dilution, drives thing air-atomizing sterilization.
CN2011102317402A 2011-08-15 2011-08-15 Composite disinfectant for livestock and poultry and using method Pending CN102349510A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106135202A (en) * 2016-06-17 2016-11-23 广州市兴达动物药业有限公司 The preparation method of a kind of foamaseptic and using method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1151180A (en) * 1994-06-20 1997-06-04 尤尼利弗公司 Improvements relating to antimicrobial cleaning compositions
CN1429488A (en) * 2001-12-30 2003-07-16 李潜德 Insecticide having antiseptic function and its preparation method and application of said insecticide in paint
US20050069566A1 (en) * 2003-08-04 2005-03-31 Foamix Ltd. Foam carrier containing amphiphilic copolymeric gelling agent
CN101374412A (en) * 2006-03-13 2009-02-25 赢创戈尔德施米特有限公司 Agrochemical composition comprising alkylene glycol modified polysiloxane

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1151180A (en) * 1994-06-20 1997-06-04 尤尼利弗公司 Improvements relating to antimicrobial cleaning compositions
CN1429488A (en) * 2001-12-30 2003-07-16 李潜德 Insecticide having antiseptic function and its preparation method and application of said insecticide in paint
US20050069566A1 (en) * 2003-08-04 2005-03-31 Foamix Ltd. Foam carrier containing amphiphilic copolymeric gelling agent
CN101374412A (en) * 2006-03-13 2009-02-25 赢创戈尔德施米特有限公司 Agrochemical composition comprising alkylene glycol modified polysiloxane

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106135202A (en) * 2016-06-17 2016-11-23 广州市兴达动物药业有限公司 The preparation method of a kind of foamaseptic and using method thereof

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Application publication date: 20120215