CN102326579A - Insecticidal composition containing cycloxaprid and synthetic pyrethroid insecticides - Google Patents

Abstract

The invention discloses an insecticidal composition containing cyclopyrid and pyrethroid insecticides and its application. Pyrethroid insecticide of cyfluthrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilicate, fenvalerate, fenvalerate, first active ingredient The weight ratio to the second active ingredient is 1:100˜100:1. The composition can be formulated into agriculturally acceptable water-dispersible granules, wettable powders, suspensions, dispersible oil suspensions, microcapsule suspensions, emulsifiable concentrates or microemulsion formulations. The composition of the invention is reasonable and the insecticidal effect is good. The drug cost is low, and its activity and insecticidal effect are not a simple superposition of the activities of each component. Compared with the existing single preparation, it not only has a significant insecticidal effect, but also has a significant synergistic effect and slows down resistance. The production of the preparation has less residual amount of the preparation, no pollution to the crops, good safety, and meets the safety requirements of the pesticide preparation.

Description

A kind of insecticidal composition containing cyclopyrid and pyrethroid insecticides

technical field

The invention relates to an insecticidal composition, in particular to an insecticidal composition of cyclopyrid and pyrethroid insecticides, and belongs to the technical field of compound pesticides.

Background technique

Cyclopyrid is a new neonicotinoid insecticide, created by East China University of Science and Technology, chemical name: 9-(6-chloropyridin-3-yl)methyl)-4-nitro-8-oxa -10,11-dihydroimidazo(2,3-a)bicyclo(3,2,1)oct-3-ene, English common name: cycloxaprid, chemical formula C ₁₄ H ₁₅ ClN ₄ O ₃ . It has systemic, stomach poisoning and contact killing effects on pests, and can be used to control Homoptera and Coleoptera pests on crops. It has no cross-resistance with imidacloprid, acetamiprid, thiamethoxam, etc., and is also effective against Lepidoptera pests. The dosage of this product is low, it is safe to the environment, and has little or no harm to beneficial organisms. It has high insecticidal activity against aphids, planthoppers, whiteflies, flea beetles, cotton bollworms, diamondback moths, Spodoptera litura, armyworms, etc. of crops such as wheat, cotton, rice, fruit trees, and vegetables. As a new type of neonicotinoid insecticide, Cyclopyrid has a high cost of use and a risk of gradually increasing resistance risk in the process of use. Reasonable mixing with different types of insecticides plays an important role in fully and effectively promoting cyclopyrid and prolonging its service life.

Lambda-cyhalothrin, English common name: Lambda-cyhalothrin, chemical name: 3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropanecarboxylic acid α- Cyano-3-phenoxybenzyl ester has a wide insecticidal spectrum, high activity, rapid drug effect, and is resistant to rain erosion after spraying, but it is easy to develop resistance to it after long-term use. There is a certain control effect on mites, but the dosage for mites should be 1-2 times higher than the conventional dosage. It is suitable for pests of peanuts, soybeans, cotton, fruit trees, and vegetables.

Beta-cypermethrin, common name Beta cypermethrin, trade name: high protection, beta-cypermethrin, this product is non-systemic but has contact and stomach poisoning insecticide. Disrupts nervous system function by interacting with pest sodium channels. Used in public health and animal husbandry to control various pests such as flies, cockroaches, mosquitoes, fleas, lice, bedbugs, animal ectoparasites such as ticks, mites, etc.

Cypermethrin, English name: Cypermethrin, other names: Mibaike, Xingmianbao, Anlubao, Saibokai, Fendina, chemical name: a-cyano-(3-phenoxybenzyl)(1RS)-cis , trans-2,2-dimethyl-3-(-2,2-dichlorovinyl) cyclopropane carboxylate, with contact killing, stomach poisoning and preventing feeding effects. It has a wide insecticidal spectrum and rapid drug effect, and it also has a killing effect on the eggs of some pests, and the residual effect period is more than 10 days.

Bifenthrin, English name bifenthrin; FMC-54800; Biphenthrin; Brigade; Capture; Talstar, alias bifenthrin; Uranus; Methyl-(Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate, with Contact and stomach poisoning, no systemic and fumigation effects, rapid insecticidal effect.

Beta-cyfluthrin, English name: beta-cyfluthrin, other names: Baode, chemical name: cyano-(4-fluoro-3-phenoxybenzyl)-methyl-(2,2-dichlorovinyl)- 2,2-Dimethylcyclopropane carboxylate has contact and stomach poisoning effects, wide insecticidal spectrum, rapid knockdown, long-lasting effect, and plants have good drug resistance to it.

Ethofenprox, common name in English: ethofenprox, other names MTI-500, Duolaibao, has the characteristics of contact and stomach toxicity, wide insecticidal spectrum, high insecticidal activity, fast knockdown speed, and long-lasting effect , safe for aquatic organisms, crops, and natural enemies. It is suitable for controlling various pests of rice, vegetables, cotton Lepidoptera, Hemiptera, Orthoptera, Coleoptera, Diptera and Isoptera. Especially the control effect on rice planthopper is remarkable, and it is also the designated product after the state prohibits the application of highly toxic pesticides on rice.

Silafluthrin, English name: silafluofen, is a new silicon-containing organic insecticide with stomach toxicity and contact action, high activity and stable chemical properties. Shows good repellent effect on termites.

Fenvalerate: English name: fenvalerate, other names: Laifuling, Sumisaldin, Zhongxifenthrin, chemical name: (S)-α-cyano-3-phenoxybenzyl (S) -2-(4-Chlorophenyl)-3-methylbutyrate. Mainly contact and stomach poisoning, no systemic and fumigation effects. Effective against Lepidoptera larvae. It also has good effect on pests of Homoptera, Orthoptera and Hemiptera.

Fenpropathrin, English name: Fenpropathrin, Chinese name: Misaoli, chemical name: α-cyano-3-phenoxybenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate. It has a wide insecticidal spectrum, long residual effect period, and good effect on many kinds of spider mites.

As a new type of neonicotinoid insecticide, cycloxaprid has high cost of use and the risk of gradually increasing resistance risk after it is launched on the market. It is highly effective against homopteran pests but poorly effective against lepidopteran pests Defects; pyrethroid insecticidal effect is good, fast-acting, but the duration is short, use year by year, the resistance develops rapidly, the inventor unexpectedly found that the mixed use of cyclopyrid and pyrethroids has The significant synergistic effect can reduce the cost of use and slow down the effect of pest resistance.

Contents of the invention

The object of the present invention is to provide a kind of insecticidal composition of cyclopyrid and pyrethroid insecticides with reasonable components, significant synergism, good insecticidal effect, low drug cost, and less resistance to drug resistance, and its preparation .

Another object of the present invention is to provide the application of the insecticidal composition of cyclopyrid and pyrethroid insecticides.

In order to overcome the defective of existing single preparation, technical scheme of the present invention solves like this:

Insecticidal compositions containing cyclopyrid and pyrethroid insecticides, comprising:

A) the first active ingredient cyclopyrid;

B) The second active ingredient is selected from the group of pyrethroid insecticides selected from lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenproxil, flusilithrin, and fenvalerate Esters, fenpropathrin;

The weight ratio of the first active ingredient to the second active ingredient is 1:100-100:1, preferably 1:50-50:1, more preferably 1:30-30:1.

The cumulative amount (total content) of the first active ingredient and the second active ingredient is 1% to 90% of the total weight of the composition, preferably 5% to 50%, and the cumulative amount of the active ingredient is also closely related to the dosage form. For example, the accumulative amount of active ingredients in a suspending agent generally does not exceed 50%.

The insecticidal composition of cyclopyridam and pyrethroid insecticides of the present invention can be prepared according to methods known to those skilled in the art. Suspension concentrate, microcapsule suspension concentrate, emulsifiable concentrate or microemulsion.

For water-dispersible granules, those skilled in the art are familiar with the use of corresponding adjuvants to complete the present invention. The dispersing agent is selected from polycarboxylate, lignosulfonate, alkyl naphthalene sulfonate; the wetting agent is selected from alkyl sulfate, alkyl sulfonate, naphthalene sulfonate; the disintegrant is selected from ammonium sulfate , urea, sucrose, glucose; the binder is selected from diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose; the filler is selected from diatomite, kaolin, white carbon black, light calcium, talcum powder , Attapulgite, clay.

For wettable powders, the auxiliary agents that can be used are: dispersant selected from polycarboxylate, lignosulfonate, alkyl naphthalene sulfonate; wetting agent selected from alkyl sulfate, alkyl sulfonate, Naphthalene sulfonate; the filler is selected from ammonium sulfate, urea, sucrose, glucose, diatomaceous earth, kaolin, white carbon black, light calcium carbonate, montmorillonite, talcum powder, attapulgite, and clay.

For suspending agent, the auxiliary agent that can be used is: dispersing agent is selected from polycarboxylate, lignin sulfonate, alkylnaphthalene sulfonate, TERSPERSE 2020 (produced by U.S. Huntsman Company, alkylnaphthalene sulfonate ); the emulsifier is selected from Nongru 700# (common name: alkylphenol formaldehyde resin polyoxyethylene ether), Span-60# (common name: sorbitan monostearate), Tween-60# ( Common name: sorbitan monostearate polyoxyethylene ether), Nongru 1601# (common name: phenylethylphenol polyoxyethylene polyoxypropylene ether), TERSPERSE 4894 (produced by Huntsman, USA); The wetting agent is selected from alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethylphenol polyoxyethylene ether phosphate, alkyl sulfate, alkylsulfonate salt, naphthalene sulfonate, TERSPERSE 2500 (produced by Huntsman, USA); thickener is selected from xanthan gum, polyvinyl alcohol, bentonite, magnesium aluminum silicate; preservative is selected from formaldehyde, benzoic acid, sodium benzoate ; Defoamer such as silicone defoamer; antifreeze selected from ethylene glycol, propylene glycol, glycerin, urea, inorganic salts such as sodium chloride.

For dispersible oil suspensions, the auxiliary agents that can be used are: dispersant is selected from polycarboxylate, lignosulfonate, alkylnaphthalene sulfonate (diffusion agent NNO), TERSPERSE 2020; emulsifier is selected from BY ( Castor oil polyoxyethylene ether) series emulsifier (BY-110, BY-125, BY-140) Nongru 700#, Nongru 2201, Span-60#, Tween-60#, Nongru 1601#, TERSPERSE 4894; Wetting agent is selected from alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethylphenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl Sulfonate, naphthalene sulfonate, TERSPERSE 2500; thickener selected from white carbon black, polyvinyl alcohol, bentonite, magnesium aluminum silicate; antifreeze selected from ethylene glycol, propylene glycol, glycerin, urea, inorganic salts such as chlorine Sodium chloride; stabilizer is selected from epoxy soybean oil, epichlorohydrin, triphenyl phosphate; dispersion medium is selected from soybean oil, rapeseed oil, corn oil, methyl oleate, diesel oil, machine oil, mineral oil.

For emulsifiable concentrates, the additives that can be used are: emulsifier selected from calcium dodecylbenzenesulfonate (Nongru 500#), Nongru 700#, Nongru 2201#, Span-60#, emulsifier T -60 (common name: sorbitan monostearate polyoxyethylene ether), TX-10 (common name: octylphenol polyoxyethylene (10) ether), Nongru 1601#, Nongru 600#, Nongru 400#; solvent selected from xylene, solvent naphtha (S-150, S-180, S-200), toluene, biodiesel, methylated vegetable oil; cosolvent selected from ethyl acetate, methanol, dimethyl Formamide, cyclohexanone, acetone, methyl ethyl ketone; the stabilizer is selected from triphenyl phosphite, epichlorohydrin, acetic anhydride.

For microemulsions, the auxiliary agents that can be used are: emulsifier selected from calcium dodecylbenzenesulfonate (Nongru 500#), Nongru 700#, Nongru 2201#, Span-60#, Tween-60 #, TX-10, agricultural milk 1601, agricultural milk 600#, agricultural milk 400#; co-emulsifier selected from methanol, isopropanol, n-butanol, ethanol; solvent selected from cyclohexanone, N-methylpyrrolidone, Xylene, toluene, mineral spirits (grades: S-150, S-180, S-200); stabilizers are selected from triphenyl phosphite, epichlorohydrin.

For microcapsule suspensions, the auxiliary agents and fillers that can be used are: solvents, emulsifiers, encapsulating monomers, wetting and dispersing agents, antifreeze agents, thickeners and water. The solvent is selected from toluene, xylene, dimethylformamide, cyclohexanone, acetone, dimethyl sulfoxide, and N-methylpyrrolidone; the emulsifier is selected from Nongru 700#, Nongru 2201#, Span-60 #, Tween-60#, TX-10, Nongru 1601#; the encapsulating monomer is selected from polyether polyol (the specification is 6305 (GB12008.2-89)), polyol modified MDI (the product specification is PMM -20, NCO (free isocyanuric acid) content is 27.0-28.0%, acid content ≤0.1%, viscosity 150±50mPas/25℃); wetting and dispersing agent is selected from alkylphenol formaldehyde resin polyoxyethylene ether sodium sulfate (SOPA), alkylphenol polyoxyethylene ether phosphate, phenylethylphenol polyoxyethylene ether phosphate; antifreeze is selected from ethylene glycol, propylene glycol, glycerin; thickener is selected from xanthan gum, polyethylene Alcohol, bentonite; preservative selected from formaldehyde, benzoic acid, sodium benzoate. The preparation process of the microcapsule suspension: after dissolving the first active ingredient and the second active ingredient in a solvent, adding a capsule-forming monomer and an emulsifier and mixing them uniformly as an oil phase, and using deionized water as a water phase. Add the oil phase to the water phase, and shear it under a high-speed shearing machine to make the particle size of the emulsion to 1-3 microns, and then solidify the microcapsules by controlling the temperature and stirring speed, and wait until the particle size of the system meets the required size. Hours to stop the encapsulation reaction, then add the dispersant, thickener, preservative and antifreeze, and stir evenly.

The composition of the invention is reasonable, the insecticidal effect is good, and the drug cost is low, and its activity and insecticidal effect are not a simple superposition of the activities of each component, but have a significant synergistic effect, which can slow down the generation of resistance and is safe for crops. Good performance, in line with the safety requirements of pesticide preparations. The invention has high insecticidal activity against aphids, planthoppers, whiteflies, flea beetles, cotton bollworms, diamondback moths, spodoptera litura, rice leaf rollers and the like in crops such as wheat, cotton, rice, fruit trees and vegetables.

Detailed ways

In order to control wheat aphids in agricultural production, the inventor used cyclopyrid and pyrethroids: beta-cyhalothrin, beta-cypermethrin, cypermethrin, bifenthrin, beta-cyfluthrin, etofenproxil, flufluthrin Ester, fenvalerate, and fenpropathrin have been researched on the synergistic effect of compounding each other. The test uses Sitobion avenae as the test object, and the specific method is: Sitobion avenae, belonging to Homoptera, Aphididae. The test drug cyclopyridin original drug was prepared by Shaanxi Shanggelu Biological Science Co., Ltd. Pyrethroids: beta-cyhalothrin, beta-cypermethrin, cypermethrin, bifenthrin, beta-cyfluthrin, etofenprox, The original drugs of flusalthrin, fenvalerate and fenvalerate are the original drugs produced by Nanjing Red Sun Group Co., Ltd., Jiangsu Yangnong Chemical Co., Ltd., and the technical department of Shaanxi Shanggelu Bioscience Co., Ltd. The original drug is prepared into the required test agent, and the test method refers to "The People's Republic of China Agricultural Industry Standard NY/T1154.6-2006". First, 5 different concentration gradients were set for the single agent and each mixed agent (on the basis of the preliminary test results, the aphid mortality rate was set according to the proportional progression within the range of 5% to 90%). The test insects are aphids collected from the field. The uniform larvae are selected in the laboratory and put into petri dishes with leaves. There are 40 worms per dish, 4 petri dishes for each treatment, and repeated 3 times. Spray under 50PSI pressure, spray one dish each time, and spray 3ml of liquid medicine per dish, then put the treated petri dish into a 12H/12H light incubator for cultivation, check the number of dead insects in 48 hours, and calculate the mortality rate. The blank control was sprayed with the same amount of water. DPS data processor software was used for statistical analysis, and the LC ₅₀ value of each agent and the co-toxicity coefficient (CTC) of the mixture were calculated to evaluate the activity of the test agent on the test insects.

The co-toxicity coefficient (CTC) ≥ 120 of the compound preparation shows a synergistic effect; CTC ≤ 80 shows an antagonistic effect; 80 < CTC < 120 shows an additive effect.

Table 1-1 Indoor toxicity determination of the combination of cyclopyrid and lambda-cyhalothrin to wheat aphids

Table 1-2 Indoor toxicity determination of the combination of cycloxaprid and beta-cypermethrin to wheat aphids

Table 1-3 Indoor toxicity determination of the combination of cycloxaprid and cypermethrin to wheat aphids

Table 1-4 Indoor toxicity test of cyclopyrid and bifenthrin combination to wheat aphids

Table 1-5 Indoor toxicity determination of the combination of cyclopyrid and beta-cyfluthrin to wheat aphids

Table 1-6 Indoor toxicity determination of cyclopyrid and etofenprox combination against wheat aphids

Table 1-7 Indoor toxicity determination of the combination of cyclopyrid and flusalthrin to wheat aphids

Table 1-8 Indoor toxicity determination of cyclopyrid and fenvalerate to wheat aphids

Table 1-9 Indoor toxicity determination of cyclopyrid and fenpropathrin to wheat aphids

The results of indoor toxicity test showed that: cyclopyrid and lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilithrin, fenvalerate, fenfenthrin The mixed use of esters at a weight ratio of 1:100 to 100:1 has good toxicity to wheat aphids, and both have significant synergistic effects.

In order to control pests such as vegetable diamondback moths in agricultural production, the inventor selected from efficient-cyhalothrin, efficient-cypermethrin, cypermethrin, bifenthrin, efficient-cyfluthrin, Etoproxil, flufluthrin, fenvalerate, and fenpropathrin have been researched on the synergistic effect of compounding each other. The test uses Plutella xylostella as the test object, and the specific method is as follows:

Plutella xylostella scientific name Plutella xylostella (L.) Lepidoptera, diamondback moth. Alias diamondback moth, square moth, two pointed. The test drug cyclopyridin original drug was prepared by Shaanxi Shanggelu Biological Science Co., Ltd. Pyrethroids: lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyhalothrin, etofenprox, fluoride The original drugs of persalmethrin, fenvalerate, and fenvalerate are those produced by Nanjing Red Sun Group Co., Ltd., Jiangsu Yangnong Chemical Co., Ltd., and the technical department of Shaanxi Shanggelu Bioscience Co., Ltd. The medicine is prepared into the required test agent, and the test method refers to the "People's Republic of China Agricultural Industry Standard NY/T1154.2-2006". Firstly, 5 different concentration gradients were set for the single agent and each mixed agent (on the basis of the preliminary test results, the death rate of Plutella xylostella was set in a proportional progression within the range of 5% to 90%). The test insects are Plutella xylostella reared indoors. Select Plutella xylostella of uniform age in the laboratory, starve for 4 to 8 hours, use a hole puncher with a diameter of 1 cm to remove leaf discs, put them into a petri dish, and pay attention to moisturizing. Use The capillary dropper starts from a low concentration, drips 1 μL to 2 μL of liquid medicine on each leaf dish, and after the solvent evaporates, it is combined with another leaf dish coated with starch paste to form a poisonous leaf dish, which is then placed in a 12-well tissue culture in the hole of the plate. Each treatment was repeated 4 times, with no less than 12 poisonous leaf discs per repetition, and the corresponding organic solvent treatment without medicament was set as a control. One test worm was placed in each well of the tissue culture plate and cultured under normal conditions. After 2 to 4 hours of inoculation, after the test insects have eaten the leaf disc containing the medicine, add clean feed to the wells of the culture plate and continue to raise until the investigation. Eliminate the test insects that have not eaten a complete leaf disc, and check for death within 48 hours. The number of insects was calculated to calculate the mortality rate. DPS data processor software was used for statistical analysis, and the LC ₅₀ value of each agent and the co-toxicity coefficient (CTC) of the mixture were calculated to evaluate the activity of the test agent on the test insects.

Table 2-1 Indoor toxicity determination of the combination of cyclopyrid and lambda-cyhalothrin to diamondback moth

Table 2-2 Indoor toxicity determination of the combination of cyclopyrid and beta-cypermethrin to diamondback moth

Table 2-3 Indoor toxicity determination of cyclopyrid and cypermethrin combination to diamondback moth

Table 2-4 Indoor toxicity determination of cyclopyrid and bifenthrin combination to Plutella xylostella

Table 2-5 Indoor toxicity determination of the combination of cyclopyrid and beta-cyfluthrin to diamondback moth

Table 2-6 Indoor toxicity determination of cyclopyrid and etofenprox combination to Plutella xylostella

Table 2-7 Indoor toxicity determination of cyclopyrid and flusalthrin combination on diamondback moth

Table 2-8 Indoor toxicity determination of cyclopyrid and fenvalerate to Plutella xylostella

Table 2-9 Indoor toxicity determination of cyclopyrid and fenpropathrin to Plutella xylostella

The results of indoor toxicity test showed that: cyclopyrid and lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilithrin, fenvalerate, fenfenthrin The mixed use of esters in a weight ratio of 1:100 to 100:1 has good toxicity to diamondback moth, and both have significant synergistic effects.

In order to prevent flea beetles on vegetables, the inventors conducted synergistic research on compounding each other with cyclopyrid and pyrethroids. The test uses flea beetle as the test object, and the specific method is as follows:

Striped flea beetle (Striped flea beetle), belongs to Coleoptera, Chrysophyteidae. The test method refers to the "People's Republic of China Agricultural Industry Standard NY/T1154.6-2006". Firstly, 5 different concentration gradients were set for the single agent and each mixed agent (on the basis of the preliminary test results, the mortality rate of flea beetle is set in the range of 5% to 90% according to the proportional progression). The test insects were adult flea beetles collected from the field. After one week of indoor breeding, uniform adults were selected and inserted into a cylinder with a diameter of 15 cm and a depth of 30 cm where the cabbage leaves were placed. Each barrel receives 30 flea armors. Wrap the underside of the cylinder with gauze and leave a small opening that can shake out the flea beetle with a rubber tie. Use a potter spray tower to spray on the inside of the cylinder under a pressure of 50PSI. Spray one cylinder at a time, and spray 5ml of the drug solution per dish. Cover the top of the cylinder after spraying, shake the flea beetle out from the lower opening after standing still for 10 minutes, and place it in a 200ml triangular flask together with the medicated cabbage heart leaf. The blank control was sprayed with the same amount of water. Cultivate in a 25°C, 12H/12H light incubator, check the number of dead insects within 48 hours, and calculate the mortality rate. DPS data processor software was used for statistical analysis, and the LC ₅₀ value of each agent and the co-toxicity coefficient (CTC) of the mixture were calculated to evaluate the activity of the test agent on the test insects.

Table 3-1 Indoor toxicity determination of the combination of cyclopyrid and lambda-cyhalothrin on flea beetle

Table 3-2 Indoor toxicity determination of the combination of cyclopyrid and beta-cypermethrin on flea beetle

Table 3-3 Indoor toxicity determination of the combination of cyclopyrid and cypermethrin on flea beetle

Table 3-4 Indoor toxicity determination of the combination of cyclopyrid and bifenthrin on flea beetle

Table 3-5 Indoor toxicity determination of the combination of cyclopyrid and beta-cyfluthrin on flea beetle

Table 3-6 Indoor toxicity determination of the combination of cyclopyrid and etofenproxil on flea beetle

Table 3-7 Indoor toxicity determination of the combination of cyclopyrid and flusalthrin on flea beetle

Table 3-8 Indoor toxicity determination of the combination of cycloxaprid and fenvalerate on flea beetle

Table 3-9 Indoor toxicity determination of the combination of cyclopyrid and fenpropathrin on the flea beetle

The results of indoor toxicity test showed that: cyclopyrid and lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilithrin, fenvalerate, fenfenthrin The mixed use of esters at a weight ratio of 1:100 to 100:1 has good toxicity to flea beetle, and both have significant synergistic effects.

In order to control rice leaf rollers in agricultural production, the inventors conducted synergistic research on compounding each other with cyclopyrid and pyrethroid insecticides. The test uses the rice leaf roller as the test object, and the specific method is as follows:

The scientific name of the rice leaf roller is Cnaphalocrocis medinalis Guenee, Lepidoptera, Mothidae. Also known as vertical roller borer, leaf roller. The test method refers to the "People's Republic of China Agricultural Industry Standard NY/T1154.2-2006". First, 5 different concentration gradients were set for the single agent and each mixed agent (on the basis of the preliminary test results, the death rate of the rice leaf roller was set in the range of 5% to 90% according to the proportional progression). The test insects are the larvae of the rice leaf roller collected in the field. The rice leaf rollers of uniform age are selected in the laboratory, starved for 4 to 8 hours, and the leaf discs are punched out with a hole punch with a diameter of 1 cm, and placed in culture. Use a capillary dropper to start from a low concentration, and drip 1 μL to 2 μL of liquid medicine on each leaf dish. After the solvent evaporates, combine it with another leaf dish coated with starch paste to form a poisonous leaf dish. Place in the wells of a 12-well tissue culture plate. Each treatment was repeated 4 times, with no less than 12 poisonous leaf discs per repetition, and the corresponding organic solvent treatment without medicament was set as a control. One test worm was placed in each well of the tissue culture plate and cultured under normal conditions. After 2 to 4 hours of inoculation, after the test insects have eaten the leaf disc containing the medicine, add clean feed to the wells of the culture plate and continue to raise until the investigation. Eliminate the test insects that have not eaten a complete leaf disc, and check for death within 24 hours. The number of insects was calculated to calculate the mortality rate. DPS data processor software was used for statistical analysis, and the LC ₅₀ value of each agent and the co-toxicity coefficient (CTC) of the mixture were calculated to evaluate the activity of the test agent on the test insects.

Table 4-1 Indoor toxicity determination of the combination of cyclopyrid and lambda-cyhalothrin against the rice leaf roller

Table 4-2 Indoor toxicity determination of the combination of cyclopyrid and beta-cypermethrin against the rice leaf roller

Table 4-3 Indoor toxicity determination of the combination of cyclopyrid and cypermethrin against the rice leaf roller

Table 4-4 Indoor toxicity determination of the combination of cyclopyrid and bifenthrin against the rice leaf roller

Table 4-5 Indoor toxicity determination of the combination of cyclopyrid and beta-cyfluthrin against the rice leaf roller

Table 4-6 Indoor toxicity determination of the combination of cyclopyrid and etofenprox against the rice leaf roller

Table 4-7 Indoor toxicity determination of the combination of cyclopyrid and flusalthrin against the rice leaf roller

Table 4-8 Indoor toxicity determination of the combination of cyclopyrid and fenvalerate against the rice leaf roller

Table 4-9 Indoor toxicity determination of the combination of cyclopyrid and fenpropathrin against the rice leaf roller

The results of indoor toxicity test showed that: cyclopyrid and lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilithrin, fenvalerate, fenfenthrin The mixed use of esters at a weight ratio of 1:100 to 100:1 has good toxicity to rice leaf roller, and both have significant synergistic effects.

In order to prevent and control rice planthoppers in agricultural production, the inventors conducted synergistic research on compounding each other with cyclopyrid and pyrethroid insecticides. The rice brown planthopper was used as the test object in the test, and the specific method was as follows:

Rice brown planthopper scientific name Nilaparvata lugens, homoptera, planthopper family. The test method refers to the "People's Republic of China Agricultural Industry Standard NY/T1154.7-2006". Firstly, 5 different concentration gradients are set for the single agent and each mixed agent (on the basis of the preliminary test results, the mortality rate of N. lugens is set in the range of 5% to 90% according to the proportional progression). The test insects are rice planthopper (brown planthopper) eggs collected from the field, and rice seedlings are used for 3 generations in the greenhouse. The uniform 3rd instar nymphs are selected and placed in a petri dish with a diameter of 12 cm for rice seedlings (treated with cotton balls for moisturizing). , each dish received 30 anesthetized nymphs, and each treatment received 4 petri dishes, sprayed with a potter spray tower at a pressure of 50PSI, sprayed one dish at a time, and sprayed 3ml of liquid medicine per dish. After the worms woke up, the treated Put the petri dish into a 12H/12H light incubator for cultivation, check the number of dead insects within 72 hours, and calculate the mortality rate. The blank control was sprayed with the same amount of water. DPS data processor software was used for statistical analysis, and the LC ₅₀ value of each agent and the co-toxicity coefficient (CTC) of the mixture were calculated to evaluate the activity of the test agent on the test insects.

Table 5-1 Indoor toxicity test of the combination of cyclopyrid and lambda-cyhalothrin against rice brown planthopper

Table 5-2 Indoor toxicity test of the combination of cyclopyrid and beta-cypermethrin against rice brown planthopper

Table 5-3 Indoor toxicity test of the combination of cyclopyrid and cypermethrin to brown planthopper

Table 5-4 Indoor toxicity determination of the combination of cyclopyrid and bifenthrin against rice brown planthopper

Table 5-5 Indoor toxicity test of cyclopyrid and beta-cyfluthrin combination against rice brown planthopper

Table 5-6 Indoor toxicity test of cyclopyrid and aldothrin combination against rice brown planthopper

Table 5-7 Indoor toxicity test of the combination of cyclopyrid and flusalthrin against rice brown planthopper

Table 5-8 Indoor toxicity test of cycloxaprid and fenvalerate to brown planthopper

Table 5-9 Indoor toxicity test of the combination of cyclopyrid and fenpropathrin against rice brown planthopper

The results of indoor toxicity test showed that: cyclopyrid and lambda-cyhalothrin, lambda-cypermethrin, cypermethrin, bifenthrin, lambda-cyfluthrin, etofenprox, flusilithrin, fenvalerate, fenfenthrin The mixed use of esters at a weight ratio of 1:100 to 100:1 has good toxicity to brown planthopper, and both have significant synergistic effects.

Formulation Example 1

Weigh 10% cyclopyrid, 10% lambda-cyhalothrin, 3% TERSPERSE 4894, 1% TERSPERSE 2500, 2% diffusing agent NNO, 0.3% xanthan gum, 5% propylene glycol, 0.5% benzoic acid, 0.5 % organosilicon defoamer (trade name: s-29 produced by Nanjing Sixin Applied Chemicals Co., Ltd.), and deionized water are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare 20% cyclopyrid-cyhalothrin suspending agent.

The formula is used to prevent and control rice stem borer, the dosage per mu is 12g, diluted and sprayed with 45kg of water, the control effect is 92.4% after 7 days of application, and 94.5% after 14 days of application. The dosage of 10% cyclopyrid SC is 20g per mu and the dosage of 10% beta-cyhalothrin SC is 20g per mu. Using the same method, the control effect of 7 days after the medicine is respectively 82.62% and 78.81%. The control effects were 78.53% and 82.85% respectively 14 days after treatment. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 2

Weigh 20% cyclopyrid, 2% beta-cypermethrin, 4% TERSPERSE 4894, 1.5% TERSPERSE 2500, 1% TERSPERSE 2020, 0.2% magnesium aluminum silicate, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone Defoamer and deionized water are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare a 22% epoxyclopyrid-beta-cypermethrin suspension concentrate.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 6g, diluted and sprayed with 45kg of water, the control effect is 90.2% after 7 days of application, and 92.6% after 14 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 4.5% beta-cypermethrin emulsifiable concentrate per mu dosage 45g, use with the same method, the control effect of 7 days after the medicine is respectively 83.4% and 61.2%, after the medicine 14 days The control effects were 82.4% and 64.6%, respectively. The compound combination of cyclopyrid and beta-cypermethrin has obvious synergistic effect, and the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 3

Weigh 20% cyclopyrid, 5% cypermethrin, 3% TERSPERSE 4894, 1.5% TERSPERSE 2500, 1% TERSPERSE 2425, 0.2% xanthan gum, 5% propylene glycol, 0.5% benzoic acid, 0.5% silicone defoamer 1. Add deionized water to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 25% epoxyclopyrid-cypermethrin suspension concentrate.

The formula is used to control rice and wheat aphids, the dosage per mu is 5g, diluted with 45kg of water and sprayed, the control effect is 98.3% after 7 days, and 95.6% after 14 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 7 days after the medicine is respectively 83.6% and 56.4%, the control effect of 14 days after the medicine The efficiency is 85.7% and 60.2% respectively. The synergistic effect of the combination of cyclopyrid and cypermethrin is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 4

Weigh 15% cyclopyrid, 5% bifenthrin, 1% diffusing agent NNO, 3% Nongru 700#, 2% Nongru 1601#, 2% TERSPERSE 2500, 0.3% xanthan gum, 5% propylene glycol , 0.5% benzoic acid, 0.5% organosilicon defoamer, and deionized water are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare a 20% cyclopyrid-bifenthrin suspending agent.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 8g, diluted and sprayed with 50kg of water, the control effect is 90.1% after 7 days of application, and 93.7% after 14 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 25 g/liter bifenthrin emulsifiable concentrate per mu dosage 80mL, using the same method, the control effect of 7 days after the medicine is respectively 83.6% and 71.4%. The control effects after 14 days were 76.2% and 58.8%, respectively. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 5

Weigh 7.5% cyclopyrid, 2.5% beta-cyfluthrin, 2% TERSPERSE 2020, 2% Span-60#, 2% Tween-60#, 1% TERSPERSE 2500, 0.5% white carbon black, 0.3% yellow Raw gum, 5% ethylene glycol, 0.5% benzoic acid, 0.5% organic silicon defoamer, and deionized water are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 10% cycloclofenac·beta-cyfluthrin suspending agent.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 12g, diluted and sprayed with 50kg of water, the control effect is 95.2% after 7 days of application, and 96.6% after 14 days of application. The dosage of 10% cyclopyrid suspending agent per mu is 20g and the dosage of 2.5% beta-cyfluthrin EC is 30mL per mu. Using the same method, the control effects are 82.4% and 72.6% respectively after 7 days of application, and 14 days after application. The control effects of the two were 84.1% and 67.9%. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 6

Weigh 2% cyclopyrid, 18% etofenproxil, 1% TERSPERSE 2020, 3% Nongru 1601#, 2% Nongru 2201#, 1% TERSPERSE 2500, 0.3% xanthan gum, 5% ethylene glycol , 0.5% formaldehyde, 0.5% silicone defoamer, deionized water added to 100% by weight. High-speed shear dispersion for 30 minutes, and sand grinding with a sand mill to prepare a 20% epoxyclopyrid-ethofenprox suspension.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 15g, diluted and sprayed with 50kg of water, the control effect is 91.7% after 3 days of application, and 92.8% after 7 days of application. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 60g per mu. Using the same method, the control effects are 81.2% and 77.1% respectively after 3 days of application, and 7 days after application. The control effects of the two are 80.6% and 75.6%, respectively. The synergistic effect of the combination of cyclopyridam and etofenproxil is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 7

Weigh 5% cyclopyrid, 5% fluthrin, 1% TERSPERSE 2020, 3% TERSPERSE 4894, 1% Tween-60#, 1% TERSPERSE 2500, 0.5% white carbon black, 0.3% xanthan gum , 5% ethylene glycol, 0.5% benzoic acid, 0.5% organosilicon defoamer, and deionized water are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 10% epoxyclopyrid-flusalate suspending agent.

The formula is used to prevent and control wheat aphids. The dosage per mu is 10g, diluted with 50kg of water and sprayed. The control effect is 95.2% after 7 days and 92.4% after 14 days. The dosage of 10% cyclopyrid suspending agent is 15g per mu and the dosage of 5% flusalthrin emulsifiable concentrate is 30g per mu. Using the same method, the control effects after 7 days of medicine are respectively 88.2% and 78.6%. The control effects of days are 86.1% and 71.9%, respectively. The synergistic effect of the combination of cyclopyrid and flusalthrin is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 8

Weigh 5% cyclopyrid, 2.5% beta-cyhalothrin, 6% calcium lignosulfonate, 3% alkylnaphthalene sulfonate formaldehyde condensate, 1% sodium lauryl sulfate, 3% white Carbon black and kaolin are added up to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 7.5% cyclopyrid-cyhalothrin wettable powder.

The formula is used to prevent and control wheat aphids. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect is 96.5% after 3 days and 92.6% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 2.5% lambda-cyhalothrin emulsifiable concentrate per mu dosage 45g, use with the same method, the control effect of 3 days after the medicine is respectively 84.7% and 76.6%. The control effects after 7 days were 83.6% and 70.5%, respectively. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 9

Weigh 30% cyclopyrid, 0.3% beta-cypermethrin, 4% calcium lignosulfonate, 5% alkylnaphthalenesulfonate formaldehyde condensate, 1.5% sodium lauryl sulfate, 10% white carbon black, light Calcium is added up to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 30.3% epoxyclopyrid-beta-cypermethrin wettable powder.

The formula is used to prevent and control wheat aphids. The dosage per mu is 5g, diluted with 50kg of water and sprayed. The control effect is 89.2% after 3 days and 87.6% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% beta-cypermethrin emulsifiable concentrate per mu dosage 60g, using the same method, the control effect is 81.2% and 79.1% respectively after 3 days of medicine, and 7 days after medicine The control effects were 83.7% and 71.5%, respectively. The compound combination of cyclopyrid and beta-cypermethrin has obvious synergistic effect, and the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 10

Weigh 30% cyclopyrid, 0.3% cypermethrin, 6% calcium lignosulfonate, 4% alkylnaphthalene sulfonate formaldehyde condensate, 1.5% sodium lauryl sulfate, 3% white carbon black, light calcium Add up to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 30.3% epoxyclopyrid-cypermethrin wettable powder.

The formula is used for preventing and treating flea beetle. The dosage per mu is 5g, diluted and sprayed with 50kg of water, and the control effect is 88.2% after 3 days and 84.6% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the drug is respectively 80.2% and 78.1%, the control effect of 7 days after the drug They are 82.5% and 72.6% respectively. The synergistic effect of the combination of cyclopyrid and cypermethrin is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 11

Weighing 30% cyclopyrid, 1% bifenthrin, 4% calcium lignosulfonate, 4% TERSPERSE 2020, 2% sodium lauryl sulfate, 5% white carbon black, kaolin added to 100% parts by weight. The above raw materials are mixed, pulverized by ultra-fine airflow and mixed to prepare 31% wettable powder of cyclopyrid-bifenthrin.

The formula is used to prevent and control rice planthopper. The dosage per mu is 5g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 89.2%, and the control effect after 7 days of application is 82.8%. 10% cyclopyrid suspending agent per mu dosage 20g and 5% bifenthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 81.7% and 76.2%, after the medicine 7 The control effect of Tian was 78.2% and 70.3%. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 12

Said 17.5% cyclopyrid, 2.5% beta-cyfluthrin, 3% TERSPERSE 2700 (polycarboxylate, produced by Huntsman, USA), 2% TERSPERSE 2020, 1% sodium lauryl sulfate, white carbon black plus up to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 20% cyclopyrid-beta-cyfluthrin wettable powder.

The formula is used to prevent and control Plutella xylostella, the dosage per mu is 8g, diluted with 50kg of water and sprayed, the control effect is 82.2% after 2 days of spraying, and 85.7% after 7 days of spraying. The dosage of 10% cyclopyrid suspending agent per mu is 20g and the dosage of 2.5% beta-cyfluthrin emulsifiable concentrate is 60g per mu. Using the same method, the control effects are respectively 77.7% and 68.2% after 2 days of application, and 7 days after application. The control effect is 81.5% and 72.4%. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 13

Weighing 0.3% cyclopyrid, 30% etofenprox, 3% calcium lignosulfonate, 2% TERSPERSE 2020, 2% sodium lauryl sulfate, 5% white carbon black, kaolin added to 100% by weight share. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 30.3% wettable powder of epoxyclopyrid-ethofenprox.

The formula is used to prevent and control rice planthopper. The dosage per mu is 30g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 88.2%, and the control effect after 7 days of application is 90.8%. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 80g per mu. Using the same method, the control effects are respectively 83.7% and 76.2% after 3 days of application, and 7 days after application. The control effect is 85.5% and 70.3%. The synergistic effect of the combination of cyclopyrid and etofenproxil is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 14

Weigh 30% cyclopyrid, 0.5% fluthrin, 6% calcium lignosulfonate, 4% alkylnaphthalene sulfonate formaldehyde condensate, 1.5% sodium lauryl sulfate, 5% white carbon black , light calcium added to 100% by weight. The above raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 30.5% epoxyclopyrid-flusalthrin wettable powder.

The formula is used to prevent and control rice planthopper. The dosage per mu is 5g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 88.2%, and the control effect after 7 days of application is 90.3%. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 5% flusalthrin emulsifiable concentrate is 30g per mu. Using the same method, the control effects of 3 days after the drug are respectively 82.6% and 78.3%. The control effects of days were 85.7% and 70.3%. The synergistic effect of the combination of cyclopyrid and flusalthrin is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 15

Weigh 3% cyclopyrid, 7% fenvalerate, 6% calcium lignosulfonate, 4% alkylnaphthalene sulfonate formaldehyde condensate, 1.5% sodium lauryl sulfate, 3% white carbon black , light calcium added to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 10% wettable powder of epoxyclopyrid-fenvalerate.

The formula is used for flea beetle flea beetle. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 87.2%, and the control effect after 7 days of application is 91.3%. 10% cyclopyrid suspending agent per mu dosage 20g and 10% fenvalerate emulsifiable concentrate per mu dosage 30g, use with the same method, the control effect of 3 days after the medicine is respectively 83.6% and 77.3%, after the medicine 7 The control effects of days were 85.7% and 70.3%. The synergistic effect of the compound combination of cycloclofenac and fenvalerate is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 16

Weigh 30% cyclopyrid, 30% fenpropathrin, 6% calcium lignosulfonate, 4% alkylnaphthalene sulfonate formaldehyde condensate, 1.5% sodium lauryl sulfate, 3% white carbon black , light calcium added to 100% by weight. The above-mentioned raw materials are mixed, pulverized by ultra-fine airflow, and mixed to prepare 60% epoxypyrid-fenpropathrin wettable powder.

The formula is used to prevent and control wheat aphids. The dosage per mu is 3g, diluted with 50kg of water and sprayed. The control effect is 95.2% after 3 days and 94.6% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 20% fenpropathrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 80.2% and 68.1%, after the medicine 7 The control effects of days are 82.5% and 62.6%, respectively. The compound combination of cyclopyrid and fenpropathrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 17

Take by weighing 10% cyclopyrid, 20% beta-cyfluthrin, 3% TERSPERSE 2700 (polycarboxylate, produced by Huntsman, U.S.), 2% diffusing agent NNO (alkyl naphthalene sulfonate formaldehyde condensate), 3% pull-off powder BX (sodium dibutylnaphthalene sulfonate), 2% K-12 (sodium lauryl sulfate), 5% corn starch, 8% ammonium sulfate, and kaolin are added to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 30% epoxacloprid·beta-cyfluthrin water-dispersible granules.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 10g, diluted with 50kg of water and sprayed, the control effect is 87.6% after 7 days, and 89.7% after 14 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% beta-cyfluthrin emulsifiable concentrate per mu dosage 40g, used in the same way, the control effect was 81.8% and 78.2% respectively in 7 days after the medicine, and 14 days after the medicine The control effects of the two were 82.5% and 71.4%. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 18

Weigh 20% cyclopyrid, 20% beta-cypermethrin, 5% TERSPERSE 2700, 3% diffusing agent NNO, 2% pull open powder BX, 1% K-12, 10% glucose, 10% ammonium sulfate, 1% carboxylate Add methylcellulose and diatomaceous earth to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 40% cycloclofenac·beta-cypermethrin water-dispersible granules.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 6g, diluted with 50kg of water and sprayed, the control effect is 90.5% after 7 days, and 93.5% after 14 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% beta-cypermethrin emulsifiable concentrate per mu dosage 30g, use with the same method, the control effect of 7 days after the medicine is respectively 82.6% and 79.8%, the 14 days after the medicine The control effects are 84.5% and 73.7% respectively. The synergistic effect is obvious after the compound combination of cyclopyrid and beta-cypermethrin, the control effect is obviously better than that of single agent, and the dosage of active ingredients is obviously reduced, which is safe for crops.

Formulation Example 19

Weigh 30% cyclopyrid, 20% cypermethrin, 3% TERSPERSE 2700, 3% sodium lignosulfonate, 1% pull open powder BX, 1% K-12, 1% PVA (molecular weight 2000), 10% sulfuric acid Ammonium and kaolin are added to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 50% epoxyclofenac-cypermethrin water-dispersible granules.

The formula is used to prevent and control wheat aphids, the dosage per mu is 5g, diluted with 50kg of water and sprayed, the control effect is 96.5% after 3 days of spraying, and 94.3% after 7 days of spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 86.5% and 80.7%, and the control effect of 7 days after the medicine is 86.5%. The efficacy is 83.6% and 72.8%, respectively, safe for crops.

Formulation Example 20

Weigh 1% cyclopyrid, 30% bifenthrin, 3% TERSPERSE 2700, 2% diffusing agent NNO, 2% pull open powder BX, 2% K-12, 10% diatomaceous earth, 8% urea, Kaolin is added to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultra-micro airflow pulverization, mixing, and granulation to prepare 31% epoxyclopyrid-bifenthrin water-dispersible granules.

The formula is used to prevent and control rice planthoppers. The dosage per mu is 8g, diluted and sprayed with 50kg of water, and the control effect is 90.5% after 3 days and 92.3% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% bifenthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 83.7% and 79.6%, after the medicine 7 The control effects of the two days are 82.5% and 68.8%, respectively, which are safe for crops.

Formulation Example 21

Weigh 20% cyclopyrid, 2.5% beta-cyfluthrin, 4% TERSPERSE 2700, 1% pull open powder BX, 1% K-12, 10% diatomaceous earth, 15% ammonium sulfate, attapulgite to 100 % parts by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 22.5% epoxacloprid·beta-cyfluthrin water-dispersible granules.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 8g, diluted with 50kg of water and sprayed, the control effect is 87.5% after 7 days, and 90.3% after 14 days. 10% cyclopyrid suspending agent per mu dosage 20g and 2.5 beta-cyfluthrin emulsifiable concentrate per mu dosage 30g, using the same method, 7 days after the drug, the control effect is 83.6% and 80.6% respectively, 14 days after the drug The control effects are 84.7% and 71.8% respectively, which are safe for crops.

Formulation Example 22

Weigh 30% cyclopyrid, 40% etofenprox, 4% TERSPERSE 2020, 3% sodium lignosulfonate, 1% pull-off powder BX, 1% carboxymethylcellulose, 3% urea, diatomaceous earth Add to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 70% epoxyclopyrid-etofenprox water-dispersible granules.

The formula is used to prevent and control rice planthopper. The dosage per mu is 3g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 93.6%, and the control effect after 7 days of application is 91.3%. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 50g per mu. Using the same method, the control effects after 3 days of application are 84.6% and 80.4% respectively, and after 7 days of application The control effects were 85.6% and 71.8%, respectively, safe for crops.

Formulation Example 23

Weigh 8% cyclopyrid, 32% fluthrin, 3% TERSPERSE 2020, 3% TERSPERSE 2700, 1% pull open powder BX, 1% carboxyethyl cellulose, 5% urea, diatomaceous earth and add to 100% parts by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulation steps to prepare 40% epoxyclopyrid-flusalthrin water-dispersible granules.

The formula is used to prevent and control cauliflower diamondback moth. The dosage per mu is 8g, diluted with 50kg of water and sprayed. The control effect is 85.6% after 3 days and 86.6% after 7 days. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 5% fluthrin emulsifiable concentrate is 30g per mu. Using the same method, the control effects of 3 days after the medicine are respectively 81.7% and 76.4%. The control effects of the two days are 78.4% and 70.5%, respectively, which are safe for crops.

Formulation Example 24

Weigh 3% cyclopyrid, 10% fenvalerate, 3% TERSPERSE 2700, 2% diffusing agent NNO, 3% pull open powder BX, 2% K-12, 3% white carbon black, 5% ammonium sulfate , diatomite is added to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 13% epoxacloprid-fenvalerate water-dispersible granules.

The formula is used to prevent and control the cauliflower diamondback moth. The dosage per mu is 15g, diluted with 50kg of water and sprayed. The control effect is 82.6% for 3 days after spraying, and 85.6% for 7 days after spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 5% fenvalerate emulsifiable concentrate per mu dosage 30g, use with the same method, the control effect of 3 days after the medicine is respectively 80.1% and 76.8%, after the medicine 7 The control effects of the two days are 79.4% and 72.3%, respectively, which are safe for crops.

Formulation Example 25

Weigh 4% cyclopyrid, 32% fenpropathrin, 3% TERSPERSE 2700, 4% diffusing agent NNO, 3% pull open powder BX, 5% K-12, 3% white carbon black, 5% ammonium sulfate , diatomite is added to 100% by weight. The above-mentioned raw materials are prepared through the conventional method for preparing water-dispersible granules, ie, mixing, ultrafine airflow pulverization, mixing, and granulating steps to prepare 36% epoxyclopyrid-fenpropathrin water-dispersible granules.

The formula is used to prevent and control wheat aphids, the dosage per mu is 15g, diluted with 50kg of water and sprayed, the control effect is 96.8% after 3 days of spraying, and 91.3% after 7 days of spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 20% fenpropathrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 88.3% and 85.2%, after the medicine 7 The control effects of days were 82.5% and 67.6%. The compound combination of cyclopyrid and fenpropathrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 26

Weigh 5% cyclopyrid, 5% lambda-cyhalothrin, 4% agricultural milk 500#, 2% agricultural milk 600#, 3% agricultural milk 2201#, 3% triphenyl phosphite, 10% bis Add methyl formamide and solvent naphtha S-180 to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to prepare 10% epoxyclopyrid-effective-cyhalothrin emulsifiable concentrate.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 20g, diluted with 50kg of water and sprayed, the control effect is 86.2% after 3 days, and 84.7% after 14 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% lambda-cyhalothrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 81.3% and 67.5%. The control effects after 14 days were 76.8% and 68.2%, respectively. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 27:

Weigh 3% cyclopyrid, 7% beta-cypermethrin, 5% agricultural milk 500#, 2% agricultural milk 400#, 3% agricultural milk 700#, 1% epichlorohydrin, 15% ethyl acetate, xylene Add to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to obtain 10% cyclopyrid-beta-cypermethrin emulsifiable concentrate.

The formula is used to prevent and control rice planthopper, the dosage per mu is 15g, diluted with 50kg of water and sprayed, the control effect is 89.8% after 3 days of application, and 86.3% after 10 days of application. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 5% beta-cypermethrin emulsifiable concentrate is 50g per mu. Using the same method, the control effects of 3 days after the drug are respectively 81.3% and 60.2%. The control effects were 82.5% and 57.6% respectively. The compound combination of cyclopyrid and beta-cypermethrin has obvious synergistic effect, and the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 28

Weigh 5% cyclopyrid, 15% cypermethrin, 5% agricultural milk 500#, 3% agricultural milk 400#, 3% agricultural milk 600#, 1% epichlorohydrin, 15% cyclohexanone, xylene plus to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to prepare 20% epoxyclopyrid-cypermethrin emulsifiable concentrate.

The formula is used to prevent and control wheat aphids, the dosage per mu is 15g, diluted with 50kg of water and sprayed, the control effect is 95.6% after 3 days of spraying, and 93.5% after 7 days of spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 50g, use with same method, the control effect of 3 days after the medicine is respectively 88.1% and 79.2%, the control effect of 7 days after the medicine The efficiency is 83.3% and 67.8% respectively. The synergistic effect of the combination of cyclopyrid and cypermethrin is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 29

Weigh 2% cyclopyrid, 8% bifenthrin, 5% Nongru 500#, 3% TX-10, 4% Nongru 1601#, 1% epichlorohydrin, 10% acetone, xylene plus to 100% by weight. The above raw materials are mixed, stirred and dissolved completely to prepare 10% cyclopyrid-bifenthrin emulsifiable concentrate.

The formula is used to prevent and control rice planthopper. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 88.7%, and the control effect after 7 days of application is 90.7%. 10% cyclopyrid suspending agent 20g per mu and 10% bifenthrin emulsifiable concentrate 50g per mu are used in the same way, and the control effects after 3 days of medicine are respectively 82.5% and 68.6%. The control effects of days were 83.5% and 68.9%. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 30

Weigh 5% cyclopyrid, 5% beta-cyfluthrin, 4% agricultural milk 500#, 4% agricultural milk 600#, 3% agricultural milk 700#, 10% acetone, 2% triphenyl phosphite, toluene to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to obtain 10% cyclopyrid-beta-cyfluthrin emulsifiable concentrate.

The formula is used to control rice leaf roller, the dosage per mu is 30g, diluted with 50kg of water and sprayed, the control effect is 87.6% after 3 days, and 89.5% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 25 g/liter beta-cyfluthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 81.3% and 69.6%, after the medicine The 10-day control effects were 82.6% and 68.8%, respectively. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 31

Weigh 5% cyclopyrid, 18% etofenproxil, 4% Nongru 500#, 6% Nongru 600#, 8% dimethylformamide, 1% epichlorohydrin, S-200 and add to 100 % parts by weight. The above raw materials were mixed, stirred and dissolved completely to obtain 23% epoxyclopyrid-etoproxil emulsifiable concentrate.

The formula is used to prevent and control wheat aphids. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect is 95.8% after 3 days and 93.7% after 14 days. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 60g per mu. Using the same method, the control effects after 3 days of application are 88.3% and 80.6% respectively, and after 14 days of application The control effects of the two were 83.6% and 71.7%. The synergistic effect of the combination of cyclopyrid and etofenproxil is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 32

Weigh 10% cyclopyrid, 5% fluthrin, 4% Nongru 500#, 6% Nongru 600#, 20% cyclohexanone, 1% epichlorohydrin, and xylene to 100% by weight share. The above-mentioned raw materials are mixed, stirred and dissolved completely to obtain 15% epoxyclopyrid-flusalthrin emulsifiable concentrate.

The formula is used to prevent and control rice planthopper. The dosage per mu is 10g, diluted with 50kg of water and sprayed. The control effect is 92.9% after 3 days and 88.6% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% flusalthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 82.5% and 71.3%, after the medicine 10 The control effects of days were 83.4% and 68.6%. The synergistic effect of the combination of cyclopyrid and flusalthrin is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 33

Weigh 5% cyclopyrid, 5% fenvalerate, 4% agricultural milk 500#, 4% agricultural milk 600#, 3% agricultural milk 700#, 10% acetone, 2% triphenyl phosphite, di Toluene was added to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to obtain 10% epoxyclopyrid-fenvalerate emulsifiable concentrate.

The formula is used for preventing and treating flea beetle. The dosage per mu is 30g, diluted and sprayed with 50kg of water, and the control effect is 87.6% after 3 days and 81.5% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% fenvalerate emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 81.3% and 69.6%, after the medicine 10 The control effects of days were 79.6% and 67.8%. The synergistic effect of the compound combination of cycloclofenac and fenvalerate is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 34

Weigh 3% cyclopyrid, 17% fenpropathrin, 4% Nongru 500#, 6% Nongru 600#, 8% dimethylformamide, 3% acetone, 1% epichlorohydrin, S -200 added to 100% by weight. The above-mentioned raw materials are mixed, stirred and dissolved completely to obtain 20% epoxyclopyrid-fenpropathrin emulsifiable concentrate.

The formula is used for preventing and treating flea beetle. The dosage per mu is 20g, diluted and sprayed with 50kg of water, and the control effect is 91.8% after 3 days of application, and 85.7% after 7 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 20% fenpropathrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 85.3% and 79.6%, after the medicine 7 The control effects of days were 83.6% and 70.0%. The compound combination of cyclopyrid and fenpropathrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 35

Weigh 5% cyclopyrid, 5% lambda-cyhalothrin, 4% TX-10, 5% agricultural milk 700#, 6% agricultural milk 500#, 4% agricultural milk 1601#, 15% cyclohexanone , 5% N-methylpyrrolidone, 5% n-butanol, 1% epichlorohydrin, after dissolving completely and mixing uniformly, deionized water is added to 100% by weight, and after stirring, 10% epoxypyrid. Lambda-cyhalothrin microemulsion.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 20g, diluted and sprayed with 50kg of water, the control effect is 88.2% after 3 days of application, and 83.7% after 14 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% lambda-cyhalothrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 80.3% and 67.5%. The control effects after 14 days were 75.8% and 68.2%, respectively. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 36

Weigh 2.5% cyclopyrid, 7.5% beta-cypermethrin, 4% agricultural milk 700#, 3% agricultural milk 500#, 6% agricultural milk 600#, 10% xylene, 5% cyclohexanone, 5% isopropyl Alcohol and 1% epichlorohydrin are completely dissolved and mixed evenly, and deionized water is added to 100% by weight, and after stirring, 10% cycloclofenac·beta-cypermethrin microemulsion is obtained.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 15g, diluted and sprayed with 50kg of water, the control effect is 86.8% after 3 days of application, and 83.3% after 10 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% beta-cypermethrin emulsifiable concentrate per mu dosage 50g, using the same method, 3 days after the drug, the control effect is respectively 80.3% and 62.2%, 10 days after the drug The control effects were 75.5% and 58.6% respectively. The compound combination of cyclopyrid and beta-cypermethrin has obvious synergistic effect, and the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 37

Weigh 2% cyclopyrid, 10% cypermethrin, 5% agricultural milk 700#, 3% agricultural milk 500#, 6% agricultural milk 600#, 10% xylene, 13% cyclohexanone, 5% ethanol, 1 % epichlorohydrin, after dissolving completely and mixing evenly, adding deionized water to 100% by weight, and stirring to obtain 12% cyclopyrid-cypermethrin microemulsion.

The formula is used for preventing and treating flea beetle. The dosage per mu is 20g, diluted and sprayed with 50kg of water, and the control effect is 90.6% after 3 days and 87.5% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 84.1% and 69.2%, and the control effect of 7 days after the medicine is 84.1% and 69.2%. The efficiency is 80.3% and 67.8% respectively. The synergistic effect of the combination of cyclopyrid and cypermethrin is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 38

Weigh 10% cyclopyrid, 8% bifenthrin, 5% Nongru 700#, 3% Nongru 500#, 6% Nongru 600#, 5% xylene, 20% cyclohexanone, 5% After ethanol is completely dissolved and mixed evenly, deionized water is added to 100% by weight, and after stirring, an 18% cyclopyrid-bifenthrin microemulsion is prepared.

The formula is used to prevent and control wheat aphids. The dosage per mu is 6g, diluted with 50kg of water and sprayed. The control effect is 95.7% after 3 days and 90.7% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% bifenthrin emulsifiable concentrate per mu dosage 30g, use with the same method, the control effect of 3 days after the medicine is respectively 86.5% and 78.6%, after the medicine 7 The control effects of days were 83.5% and 78.9%. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 39

Weigh 3% cyclopyrid, 5% beta-cyfluthrin, 5% Nongru 700#, 3% Nongru500#, 6% Nongru600#, 10% xylene, 13% cyclohexanone, 5% ethanol , 1% epichlorohydrin, after dissolving completely and mixing evenly, adding deionized water to 100% by weight, and stirring to prepare 8% epiclofenac·beta-cyfluthrin microemulsion.

The formula is used to control rice leaf roller, the dosage per mu is 18g, diluted with 50kg of water and sprayed, the control effect is 88.6% after 3 days of application, and 85.5% after 10 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% beta-cyfluthrin emulsifiable concentrate per mu dosage 50g, using the same method, the control effect is respectively 81.1% and 69.2% after 3 days of medicine, 7 days after medicine The control effects of these were 72.3% and 67.8%, respectively. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 40

Weigh 5% cyclopyrid, 10% etofenproxil, 4% TX-10, 5% Nongru 700#, 6% Nongru 500#, 4% Nongru 1601#, 15% cyclohexanone, 5% N-Methylpyrrolidone, 5% n-butanol, 1% epichlorohydrin, completely dissolved and mixed uniformly, deionized water was added to 100% by weight, and after stirring, 15% cyclopyrid-etrafenprox was obtained Microemulsion.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 18g, diluted and sprayed with 50kg of water, the control effect is 89.8% after 3 days of application, and 82.7% after 14 days of application. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 50g per mu. Using the same method, the control effects are 85.3% and 80.6% respectively after 3 days of application, and 14 days after application. The control effects of the two were 73.6% and 71.7%. The synergistic effect of the combination of cyclopyrid and etofenproxil is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 41

Weigh 10% cyclopyrid, 10% fluthrin, 3% TX-10, 4% agricultural milk 700#, 3% agricultural milk 500#, 6% agricultural milk 1601#, 30% cyclohexanone, 3 % n-butanol, 1% epichlorohydrin, completely dissolved and mixed uniformly, deionized water is added to 100% by weight, and after stirring, 20% cyclopyrid-etoproxil microemulsion is obtained.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 6g, diluted with 50kg of water and sprayed, the control effect is 92.9% after 3 days, and 88.6% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% flusalthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 82.5% and 71.3%, after the medicine 10 The control effects of days were 81.0% and 68.6%. The synergistic effect of the combination of cyclopyrid and flusalthrin is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 42

Weigh 5% cyclopyrid, 5% fenvalerate, 5% agricultural milk 700#, 3% agricultural milk 500#, 6% agricultural milk 600#, 10% xylene, 13% cyclohexanone, 5% Ethanol and 1% epichlorohydrin are completely dissolved and mixed evenly, and deionized water is added to 100% by weight, and stirred to prepare 10% epoxypyrid-fenvalerate microemulsion.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 30g, diluted and sprayed with 50kg of water, the control effect is 87.6% after 3 days, and 81.5% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% fenvalerate emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 81.3% and 68.6%, after the medicine 10 The control effects of days were 79.1% and 67.0%, respectively. The synergistic effect of the compound combination of cycloclofenac and fenvalerate is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 43

Weigh 5% cyclopyrid, 17% fenpropathrin, 4% TX-10, 5% agricultural milk 700#, 6% agricultural milk 500#, 4% agricultural milk 1601#, 15% cyclohexanone, 5% % N-methylpyrrolidone, 5% n-butanol, 1% epichlorohydrin, completely dissolved and mixed evenly, deionized water is added to 100% by weight, and after stirring, 22% epoxypyrid·methanamide is obtained Permethrin microemulsion.

The formula is used to control Plutella xylostella, the dosage per mu is 20g, diluted with 50kg of water and sprayed, the control effect is 88.8% after 3 days of spraying, and 85.7% after 7 days of spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 20% fenpropathrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 83.3% and 69.6%, after the medicine 7 The control effects of days were 78.6% and 65.5%. The compound combination of cyclopyrid and fenpropathrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 44

Weigh 5% cyclopyrid, 5% lambda-cyhalothrin, 2% TERSPERSE 2020, 4% Span-60#, 3% Tween-60#, 4% Nongru 2201#, 3% Nongru 700#, 1% TERSPERSE 2500, 0.5% white carbon black, 5% propylene glycol, 1% epichlorohydrin, and methyl oleate are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 10% epoxaprid-cyhalothrin dispersible oil suspension concentrate.

The formula is used to prevent and control wheat aphids. The dosage per mu is 8g, diluted with 50kg of water and sprayed. The control effect is 96.4% after 3 days and 94.5% after 7 days. The dosage of 10% cyclopyrid SC is 20g per mu and the dosage of 10% beta-cyhalothrin SC is 20g per mu. Using the same method, the control effects of 3 days after the medicine are respectively 88.62% and 78.81%. The control effects after 7 days of administration were 89.53% and 82.85% respectively. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 45

Weigh 10% cyclopyrid, 5% beta-cypermethrin, 2% diffusing agent NNO, 3% Nongru 2201#, 10% BY-110, 1% TERSPERSE 2500, 1% magnesium aluminum silicate, 3% glycerin, 15 % epoxidized soybean oil and soybean oil are added to 100% by weight. The above-mentioned raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare 15% epoxaprid·beta-cypermethrin dispersible oil suspension concentrate.

The formula is used to prevent and control wheat aphids. The dosage per mu is 10g, diluted with 50kg of water and sprayed. The control effect is 95.7% after 3 days and 90.7% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 5% beta-cypermethrin emulsifiable concentrate per mu dosage 50g, using the same method, the control effect is 86.5% and 78.6% respectively after 3 days of medicine, and 7 days after medicine The control effects were 82.5% and 77.9% respectively. The compound combination of cyclopyrid and beta-cypermethrin has obvious synergistic effect, and the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 46

Weigh 2% cyclopyrid, 10% cypermethrin, 1.5% TERSPERSE 2020, 3% Span-60#, 3% Tween-60#, 8% BY-110, 1% TERSPERSE 2500, 0.5% white carbon black , 5% propylene glycol, 20% epoxidized soybean oil, and methyl oleate are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 12% epoxaprid-cypermethrin dispersible oil suspension concentrate.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 20g, diluted with 50kg of water and sprayed, the control effect is 90.6% after 3 days, and 87.5% after 10 days. 10% cyclopyrid suspending agent per mu dosage 20g and 10% cypermethrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 84.1% and 69.2%, and the control effect of 7 days after the medicine is 84.1% and 69.2%. The efficiency is 81.3% and 67.6% respectively. The synergistic effect of the combination of cyclopyrid and cypermethrin is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 47

Weigh 15% cyclopyrid, 5% bifenthrin, 3% TERSPERSE 2020, 5% Span-60#, 3% Tween-60#, 2% TERSPERSE 2500, 0.5% white carbon black, 5% Propylene glycol, 0.5% benzoic acid, 1% epichlorohydrin, and methyl oleate are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 20% epoxypyrid bifenthrin dispersible oil suspension concentrate.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 8g, diluted with 50kg of water and sprayed, the control effect is 90.1% after 3 days of application, and 93.7% after 10 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 25 g/liter bifenthrin emulsifiable concentrate per mu dosage 80mL, using the same method, the control effect of 3 days after the medicine is respectively 82.6% and 70.4%. The control effects after 10 days were 76.2% and 68.8%, respectively. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 48

Weigh 16.5% cyclopyrid, 3.5% beta-cyfluthrin, 1% diffusing agent NNO, 5% BY-125, 3% Span-60#, 3% Tween-60#, 4% Nongru 1601#, 1% phenethylphenol polyoxyethylene ether phosphate, 0.5% bentonite, 5% glycerin, 3% triphenyl phosphate, and rapeseed oil are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 20% epoxacloprid·beta-cyfluthrin dispersible oil suspension concentrate.

The formula is used to prevent and control Plutella xylostella, the dosage per mu is 9g, diluted and sprayed with 50kg of water, the control effect is 83.2% after 2 days of spraying, and 88.7% after 7 days of spraying. 10% cyclopyrid suspending agent per mu dosage 20g and 2.5% beta-cyfluthrin emulsifiable concentrate per mu dosage 60g, using the same method, the control effect is 75.7% and 66.2% respectively after 2 days of medicine, 7 days after medicine The control effect is 80.5% and 72.9%. The synergistic effect of cyclopyrid and beta-cyfluthrin compound combination is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 49

Weigh 4.5% cyclopyrid, 9.5% etofenproxil, 2% TERSPERSE 2020, 4% Span-60#, 3% Tween-60#, 4% Nongru 2201#, 3% Nongru 700#, 1% TERSPERSE 2500, 0.5% white carbon black, 5% propylene glycol, 1% epichlorohydrin, and methyl oleate are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 15% epoxypyrid-etofenprox dispersible oil suspension concentrate.

The formula is used to prevent and control rice planthopper. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect is 88.8% after 3 days and 83.7% after 14 days. The dosage of 10% cyclopyrid suspending agent is 20g per mu and the dosage of 20% etofenproxil emulsifiable concentrate is 50g per mu. Using the same method, the control effects are 82.3% and 80.6% respectively after 3 days of application, and 14 days after application. The control effects of the two were 73.3% and 71.8%. The synergistic effect of the combination of cyclopyrid and etofenproxil is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 50

Weigh 8.5% cyclopyrid, 6.5% flusalthrin, 3% TERSPERSE 2020, 5% Span-60#, 3% Tween-60#, 2% TERSPERSE 2500, 0.5% white carbon black, 5% Propylene glycol, 0.5% benzoic acid, 1% epichlorohydrin, and methyl oleate are added to 100% by weight. The above raw materials were mixed, dispersed at high speed for 30 minutes, and sanded with a sand mill to prepare a 15% epoxypyrid-flusalthrin oil suspension concentrate.

The formula is used to prevent and control rice planthoppers, the dosage per mu is 12g, diluted and sprayed with 50kg of water, the control effect is 90.9% after 3 days of application, and 87.6% after 10 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% flusalthrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 82.5% and 71.8%, after the medicine 10 The control effects of days were 83.7% and 68.5%. The synergistic effect of the combination of cyclopyridam and flusalthrin is obvious, the control effect is obviously better than that of single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 51

Weigh 4.5% cyclopyrid, 5.5% fenvalerate, 1% diffusing agent NNO, 5% BY-125, 3% Span-60#, 3% Tween-60#, 4% Nongru 1601# , 1% phenethylphenol polyoxyethylene ether phosphate, 0.5% bentonite, 5% glycerin, 3% triphenyl phosphate, and rapeseed oil are added to 100% by weight. The above-mentioned raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare 10% epoxyclopyrid-fenvalerate dispersible oil suspension concentrate.

The formula is used to prevent and control rice leaf roller, the dosage per mu is 30g, diluted and sprayed with 50kg of water, the control effect is 88.6% after 3 days of application, and 82.5% after 10 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% fenvalerate emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 80.3% and 68.7%, after the medicine 10 The control effects of days were 78.6% and 66.9%. The synergistic effect of the compound combination of cycloclofenac and fenvalerate is obvious, the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 52

Weigh 2.5% cyclopyrid, 17.5% fenpropathrin, 2% TERSPERSE 2020, 4% Span-60#, 3% Tween-60#, 4% Nongru 2201#, 3% Nongru 700# , 1% TERSPERSE 2500, 0.5% white carbon black, 5% propylene glycol, 1% epichlorohydrin, methyl oleate added to 100% by weight. The above-mentioned raw materials were mixed, dispersed at high speed for 30 minutes, and sand-milled with a sand mill to prepare 20% epoxypyrid-fenpropathrin dispersible oil suspension concentrate.

The formula is used to prevent and control wheat aphids. The dosage per mu is 20g, diluted with 50kg of water and sprayed. The control effect is 95.8% after 3 days and 88.7% after 7 days. 10% cyclopyrid suspending agent per mu dosage 20g and 20% fenpropathrin emulsifiable concentrate per mu dosage 60g, use with the same method, the control effect of 3 days after the medicine is respectively 85.3% and 79.9%, after the medicine 7 The control effects of days were 83.6% and 70.8%. The compound combination of cyclopyrid and fenpropathrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 53

Weigh 4.5% cyclopyrid, 5.5% lambda-cyhalothrin, solvent toluene 15%, N-methylpyrrolidone 5%, encapsulating monomer PMM-203%, emulsifier TX-104%, emulsifier 22012 %, dispersant alkylphenol polyoxyethylene ether phosphate 4%, thickener xanthan gum 0.3%, antifreeze agent ethylene glycol 4%, 0.5% benzoic acid, deionized water to make up 100%. After the two active components of cyclopyrid and lambda-cyhalothrin are heated and dissolved with solvent toluene and N-methylpyrrolidone, the encapsulation monomer and emulsifier are added and mixed uniformly as the oil phase, and the remaining water is used as the water Mutually. With a high-speed shearing machine at 8000 rpm, add the oil phase to the water phase and shear for 10-15 minutes to obtain an emulsion. Take a sample to measure the particle size of the emulsion, and the average particle size should be 3 microns. Then transfer the emulsion to a reaction kettle with a thermometer and a stirrer, heat the temperature to 45°C, and stir at a speed of 500 rpm, so that the encapsulating monomer slowly undergoes interfacial polymerization reaction on the emulsion particles, and on the surface of the particles Gradually form a microporous structure capsule. After the system has reacted for 3-3.5 hours, take a sample to measure the particle size, and the average particle size is about 5 microns, and the encapsulation reaction stage is over. Then the temperature is raised to 65° C., and the reaction of the system is transferred from the encapsulation reaction stage to the encapsulation curing stage, and the curing stage takes 1-1.5 hours. After the curing stage of the capsule skin is over, the temperature of the system returns to room temperature, and then the wetting and dispersing agent, thickener, antifreeze, and preservative are added, and stirred at a speed of 800 rpm for 30 minutes to obtain 10% cyclopyrid ·Beta-cyhalothrin microcapsule suspension.

The formula is used to prevent and control rice planthopper, the dosage per mu is 20g, diluted with 50kg of water and sprayed, the control effect is 87.2% after 3 days of application, and 85.1% after 7 days of application. 10% cyclopyrid suspending agent per mu dosage 20g and 5% lambda-cyhalothrin emulsifiable concentrate per mu dosage 50g, use with the same method, the control effect of 3 days after the medicine is respectively 79.3% and 67.5%. The control effects after 7 days were 76.6% and 68.1%, respectively. The compound combination of cyclopyrid and lambda-cyhalothrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

Formulation Example 54

Weigh 2% cyclopyrid, 8% bifenthrin, solvent xylene 10%, 10% cyclohexanone, encapsulation monomer polyether polyol 63054%, emulsifier Nongru 700# 3%, emulsifier 22012%, dispersant phenethylphenol polyoxyethylene ether phosphate 4%, alkylphenol formaldehyde resin polyoxyethylene ether sodium sulfate (SOPA) 2%, thickener xanthan gum 0.3%, antifreeze agent propylene glycol 4% , 0.5% sodium benzoate, deionized water make up 100%. The two active components of cyclopyrid and bifenthrin are heated and dissolved with solvent xylene and cyclohexanone, and the encapsulating monomer and emulsifier are added and mixed uniformly to form an oil phase, and the remaining water is used as a water phase. With a high-speed shearing machine at 8000 rpm, add the oil phase to the water phase and shear for 10-15 minutes to obtain an emulsion. Take a sample to measure the particle size of the emulsion, and the average particle size should be 3 microns. Then transfer the emulsion to a reaction kettle with a thermometer and a stirrer, heat the temperature to 45°C, and stir at a speed of 500 rpm, so that the encapsulating monomer slowly undergoes interfacial polymerization reaction on the emulsion particles, and on the surface of the particles Gradually form a microporous structure capsule. After the system has reacted for 3-3.5 hours, take a sample to measure the particle size, the average particle size is about 5 microns, and the encapsulation reaction stage ends. Then the temperature is raised to 65° C., and the system reaction is transferred from the encapsulation reaction stage to the encapsulation curing stage, and the curing stage takes 1-1.5 hours. After the curing stage of the capsule skin is over, the temperature of the system returns to room temperature, and then the wetting and dispersing agent, thickener, antifreeze, and preservative are added, and stirred at a speed of 800 rpm for 30 minutes to obtain 10% cyclopyrid · Bifenthrin microcapsule suspension.

The formula is used for preventing and treating flea beetle. The dosage per mu is 30g, diluted with 50kg of water and sprayed. The control effect after 3 days of application is 89.9%, and the control effect after 7 days of application is 90.7%. 10% cyclopyrid suspending agent 20g per mu and 10% bifenthrin emulsifiable concentrate 50g per mu are used in the same way, and the control effects after 3 days of medicine are respectively 82.5% and 68.6%. The control effects of days were 83.5% and 67.1%. The compound combination of cyclopyridam and bifenthrin has obvious synergistic effect, and the control effect is obviously better than that of a single agent, and the dosage of active ingredients is significantly reduced, which is safe for crops.

As can be seen from the above examples, the first active ingredient cyclopyrid and the second active ingredient beta-cyhalothrin, beta-cypermethrin, cypermethrin, bifenthrin, beta-cyfluthrin, etofenprox, flusilicate , fenvalerate, and fenvalerate can be made into water-dispersible granules, wettable powders, suspension concentrates, dispersible oil suspension concentrates, microcapsule suspension concentrates, emulsifiable concentrates or microemulsion formulations, which are effective against wheat aphids, Plutella xylostella, yellow flea beetle, rice brown planthopper, and rice leaf roller have significant control effects, with less dosage and high control effect, which saves the cost and dosage of medication, and is safe for crops. Therefore, production There are broad application prospects.

In summary, the composition of the present invention adopts a compounding scheme of two active ingredients, and its activity and insecticidal effect are not a simple superposition of the activities of each component. Compared with the existing single preparation, in addition to having significant insecticidal In addition to the effect, it also has a significant synergistic effect, slows down the generation of resistance, has less residue in the preparation, has no pollution to crops, has good safety, and meets the safety requirements of pesticide preparations.

Claims (9)

1. An insecticidal composition containing cyclopyrid and pyrethroid insecticides, characterized in that the insecticidal composition comprises active ingredient cyclopyrid and pyrethroid insecticides, cyclopyrid The weight ratio with the pyrethroid insecticide is (1:100)～(100:1). 2. according to the described insecticidal composition of cyclopyrid and pyrethroid insecticides according to claim 1, it is characterized in that: the weight ratio of cyclopyrid and pyrethroid insecticides is (1: 50) ~ (50:1). 3. according to the described insecticidal composition of cyclopyrid and pyrethroid insecticides according to claim 2, it is characterized in that: the weight ratio of cyclopyrid and pyrethroid insecticides is (1: 30) ~ (30:1). 4. According to the insecticidal composition containing cyclopyrid and pyrethroid insecticides according to any one of claims 1 to 3, it is characterized in that: the pyrethroid insecticides are selected from the group consisting of efficient cyhalothrin Ester, Beta-cypermethrin, Cypermethrin, Bifenthrin, Beta-cyfluthrin, Etoproxil, Flufluthrin, Fenvalerate, Fenpropathrin. 5. according to the described insecticidal composition of cyclopyrid and pyrethroid insecticides according to claim 1, it is characterized in that: the cumulative amount of cyclopyrid and pyrethroid insecticides is the combination 1% to 90% of the total weight of the product. 6. according to the described insecticidal composition of cyclopyrid and pyrethroid insecticides according to claim 5, it is characterized in that: the cumulative amount of cyclopyrid and pyrethroid insecticides is the combination 5% to 50% of the total weight of the product. 7. The insecticidal composition containing cyclopyridam and pyrethroid insecticides according to claim 1, characterized in that the composition can be formulated into any agriculturally acceptable dosage form. 8. the insecticidal composition containing cyclopyrid and pyrethroid insecticides according to claim 7, is characterized in that said composition is water dispersible granule, wettable powder, suspending agent, dispersible oil Suspension concentrate, microcapsule suspension concentrate, emulsifiable concentrate or microemulsion. 9. The insecticidal composition containing cyclopyridam and pyrethroid insecticides described in claim 1 is used in the control of wheat aphids, vegetable diamondback moth, flea beetle, rice leaf roller, and rice planthopper pests use in .