CN102284124A - Preparation method of wound surface filling dressing for surgical wound surface vacuum sealing drainage - Google Patents
Preparation method of wound surface filling dressing for surgical wound surface vacuum sealing drainage Download PDFInfo
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- CN102284124A CN102284124A CN 201110148013 CN201110148013A CN102284124A CN 102284124 A CN102284124 A CN 102284124A CN 201110148013 CN201110148013 CN 201110148013 CN 201110148013 A CN201110148013 A CN 201110148013A CN 102284124 A CN102284124 A CN 102284124A
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- 206010052428 Wound Diseases 0.000 title claims abstract description 51
- 208000027418 Wounds and injury Diseases 0.000 title claims abstract description 51
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 238000007789 sealing Methods 0.000 title claims abstract description 14
- 208000002847 Surgical Wound Diseases 0.000 title claims abstract description 12
- 235000009814 Luffa aegyptiaca Nutrition 0.000 claims abstract description 69
- 244000302544 Luffa aegyptiaca Species 0.000 claims abstract description 69
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 17
- 230000001954 sterilising effect Effects 0.000 claims abstract description 11
- 238000004140 cleaning Methods 0.000 claims abstract description 7
- 238000001035 drying Methods 0.000 claims abstract description 6
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000012528 membrane Substances 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 7
- 230000009469 supplementation Effects 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 229920002101 Chitin Polymers 0.000 claims description 4
- 239000003292 glue Substances 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 238000005520 cutting process Methods 0.000 abstract description 3
- 238000005469 granulation Methods 0.000 abstract description 3
- 230000003179 granulation Effects 0.000 abstract description 3
- 239000004744 fabric Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 229920001661 Chitosan Polymers 0.000 abstract 1
- 239000007888 film coating Substances 0.000 abstract 1
- 238000009501 film coating Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 230000003020 moisturizing effect Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 13
- 239000011159 matrix material Substances 0.000 description 12
- 241000255789 Bombyx mori Species 0.000 description 6
- 239000006260 foam Substances 0.000 description 6
- 239000004372 Polyvinyl alcohol Substances 0.000 description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 description 4
- 239000002344 surface layer Substances 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 108010022355 Fibroins Proteins 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
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- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000195474 Sargassum Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
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- 238000013461 design Methods 0.000 description 1
- 238000002682 general surgery Methods 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
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- 238000002639 hyperbaric oxygen therapy Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
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- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
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- 239000013589 supplement Substances 0.000 description 1
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Abstract
The invention discloses a preparation method of a wound surface filling dressing for surgical wound surface vacuum sealing drainage, which comprises the following steps: firstly, removing seeds from a ripe vegetable sponge, cleaning and drying for later use; secondly, cutting the vegetable sponge into the shape matched with the wound surface, wherein the thickness of the vegetable sponge does not exceed 4 centimeters; thirdly, wrapping the vegetable sponge with a microporous fabric, or attaching the microporous fabric on the upper and lower surfaces of the vegetable sponge; fourthly, carrying out high-pressure high-temperature steam sterilization on the formed vegetable sponge, and moisturizing the sterilized filling dressing; fifthly, putting the sterile vegetable sponge into a sterile chitosan solution or silver ion solution to carry out film coating; and finally, putting the vegetable sponge into a sterile packaging bag to obtain the wound surface filling dressing based on vegetable sponge. The vegetable sponge substrate disclosed by the invention can not be easily corroded and has a longer service life; and the bacterium proliferation on the substrate surface can be inhibited, thereby promoting the growth of the granulation on the wound surface, thereby avoiding irritation caused by frequent changes of the dressing, and lowering the probability of infections.
Description
Technical field
The present invention relates to adopt closed negative pressure drainage to fill the preparation method of dressing with wound surface.
Background technology
The notion of negative-pressure sealed drainage technology (vacuum sealing drainage/VSD, be called for short VSD technology) the earliest by German ULM doctor Fleischmann of university in initiative in 1992, and form six and take turns blank, be used for the drain of extremity wound surface.1997, Morykways etc. discovered that this device can promote the wound surface local blood circulation, promoted post bud tissue to generate, and reduced tissue bacterial content, improved flap or free skin-grafting survival rate.Confirmation such as Moues afterwards, the negative-pressure sealed drainage technology is compared with traditional moistening dressing wrapping, significantly shortens wound healing time.Fbaian compares more with hyperbaric oxygentherapy by experimental study discovery negative pressure drainage can promote granulation tissue hyperplasia; Couttefangeas finds that the cell that soaks on the adjuvant of wound filling is mainly the granulocyte composition, and CD4 (+) function T cell can promote the cleaning in the wound surface, and good microenvironment is provided.Labanaris etc. discovered that VSD can promote the hypertrophy of wound surface surrounding tissue lymph pipe network in 2009.More and more scholars has confirmed VSD Clinical application effect by a large amount of research and clinical practice, and its theoretical research is updated, and states such as Germany in 2003, Austria include this technology in wound treatment guide.
The negative-pressure sealed drainage technology is meant with the polyethylene ethanol aquation Sargassum salt foam dressing (VSD adjuvant) that contains drainage tube, cover or fill the wound surface of skin, soft tissue defects, the biological semipermeable membrane of reuse seals it, make it become a confined space, at last drainage tube is connected negative pressure source, promote a kind of brand-new Therapeutic Method of wound healing by controllable negative pressure.The VSD technology is widely used in China: fields such as traumatology department, orthopaedics, department of general surgery, Department of B urn.
Existing VSD technology basic configuration comprises negative pressure source (comprising central negative pressure device or negative pressure drainage vessel that medical attractor, hospital use), drainage tube, the breathable films of polyvinyl alcohol foam or other medical porous foam, sponge or gauze (being called for short the porous foam cushion), Pasting sealing usefulness, joint (comprising two pass joints, three way cock or multiple-pass joint), drainage container etc.
The VSD technology is the product that traditional negative pressure drainage method is combined with closure dressing, and it produces machinery and biological effect by forming negative pressure at wound surface, promotes wound healing.Therefore must use special-purpose wound surface to fill dressing, existing wound surface is filled dressing porous foam cushion, it requires inside to keep clear, to guarantee that the tissue that vacuum suction goes out can be by normal sucking-off, common used material is a polyvinyl alcohol, and require the foam micro-pore diameter at 0.2-1.0mm, and polyvinyl alcohol cost height, the manufacturing process complexity, mainly depend on import at present, simultaneously the required quantity of each patient treatment is more, causes this type of Therapeutic Method cost very high, has increased heavy financial burden to the patient.Therefore, a kind of substitute products cheaply of exploitation are task of top priority.
The inventor has invented the closed negative pressure drainage of a kind of surgical wound and has filled dressing and preparation method with wound surface, its wound surface is filled dressing and is substituted polyvinyl alcohol with vegetable sponge, reduced cost, but, the vegetable sponge matrix of the closed negative pressure drainage of this surgical wound in use, can be by germ contamination, making has a large amount of bacterial multiplications in the dressing; Influenced the effect of treatment.
Summary of the invention
The invention provides the closed negative pressure drainage of a kind of surgical wound and fill the preparation method of dressing with wound surface, problem to be solved be based on the porous dressing that uses in the existing closed negative pressure drainage technology as the vegetable sponge matrix in use easily by germ contamination, produce the value-added problem of a large amount of antibacterials in the porous dressing.
The present invention realizes by following technology:
The closed negative pressure drainage of a kind of surgical wound is filled the preparation method of dressing with wound surface, and its step is as follows:
At first, sophisticated vegetable sponge is gone seed, cleaning, drying for standby;
Secondly, vegetable sponge is cut into the shape that matches with the wound surface profile, thickness is no more than 4 centimetres;
The 3rd, with micropore lining parcel vegetable sponge or be mounted on the upper and lower surface of vegetable sponge;
The 4th, the vegetable sponge that is shaped is carried out the high temperature and high pressure steam sterilization, the filling dressing after the sterilization is preserved moisture;
The 5th, with aseptic vegetable sponge, insert in aseptic chitin solution or the silver ion solution and carry out coating;
At last, the vegetable sponge of above-mentioned preparation gained is placed aseptic package bag promptly get and fill dressing based on the wound surface of vegetable sponge.
Described step comprises and will fix in the end insertion vegetable sponge of drainage tube, liquid supplementation pipe and by suture.
Comprise forming and fill the movably preparation method of the required semipermeable membrane of enclosed cavity of dressing, the steps include:
(1) middle section of semipermeable membrane is set to not have the bright zone that glue can be opened, and is provided with mounted and removable sealing paste at the position that can open;
What (2) the edge district of semipermeable membrane was set to permeable watertight has an adhesivity district;
Beneficial effect of the present invention:
1, vegetable sponge matrix of the present invention in use is difficult for being corroded through after the surface treatment, and the life-span prolongs.
2, the vegetable sponge matrix suppresses the matrix surface bacterial multiplication through after the surface treatment, promotes the growth of wound surface granulation.
3, the skin incision based on closed negative pressure drainage technology pastes, and can provide persistent dried clean for otch, avoids the stimulation of repeatedly changing dressings, and reduces and infects probability.
4, the filling dressing moving window of the present invention's design can be observed skin incision at any time, understands the otch situation, and wound can in time be handled.
5, portable depression drainage device is convenient to accept patient that closed negative pressure drainage technology treats and is carried out early rehabilitation and take exercise.
Description of drawings
Fig. 1 is the structural representation that closed wound surface of the present invention is filled dressing.
Fig. 2 is the structural representation that can open the closed wound surface filling of the semipermeable membrane dressing of window.
Wherein, 1-vegetable sponge matrix; 2-micropore lining bottom; 3-micropore lining surface layer; The 4-semipermeable membrane; The 5-suction catheter; The 6-liquid supplementation pipe; The window that 7-can open.
The specific embodiment
The present invention is further illustrated below in conjunction with drawings and Examples.
Embodiment 1
The manufacturing step that the closed negative pressure drainage of surgical wound of the present invention is filled dressing with wound surface is as follows:
At first, sophisticated vegetable sponge is gone seed, cleaning, drying for standby;
Secondly, vegetable sponge is cut into the shape that matches with the wound surface profile, control its thickness and be no more than 4 centimetres; Shape can be cut into different shape according to clinical needs, as strip, square, circular, oval, triangle etc.;
The 3rd, the vegetable sponge of cutting forming is carried out high-temperature sterilization; Can adopt conventional sterilization method of medical treatment and conventional sterilisation temp to carry out disinfection, sterilisation temp gets final product between 100-150 ℃;
The 4th, under gnotobasis with the sterile vegetable sponge of micropore lining (as silkworm silk gauze, staple gauze or rubber with holes) parcel or be mounted on the upper and lower surface of sterile vegetable sponge;
The 5th, with aseptic vegetable sponge, insert in the aseptic chitin solution and carry out coating;
At last, the vegetable sponge of above-mentioned preparation gained is placed aseptic package bag promptly get and fill dressing based on the wound surface of vegetable sponge.
The closed negative pressure drainage of a kind of surgical wound is filled the preparation method of dressing with wound surface, and its step is as follows:
At first, sophisticated vegetable sponge is gone seed, cleaning, drying for standby;
Secondly, vegetable sponge is cut into the shape that matches with the wound surface profile, thickness is no more than 4 centimetres;
The 3rd, with micropore lining parcel vegetable sponge or be mounted on the upper and lower surface of vegetable sponge;
The 4th, the vegetable sponge that is shaped is carried out the high temperature and high pressure steam sterilization, the filling dressing after the sterilization is preserved moisture;
The 5th, with aseptic vegetable sponge, insert and carry out coating in the aseptic silver ion solution;
The 6th, will fix in the end insertion vegetable sponge of drainage tube, liquid supplementation pipe and by suture;
The 7th, form and fill the movably preparation method of the required semipermeable membrane of enclosed cavity of dressing, the steps include:
(1) middle section of semipermeable membrane is set to not have the window that glue can be opened, and is provided with mounted and removable sealing paste sealing at the position that can open;
What (2) the edge district of semipermeable membrane was set to permeable watertight has an adhesivity district;
At last, the vegetable sponge of above-mentioned preparation gained is placed aseptic package bag promptly get and fill dressing based on the wound surface of vegetable sponge.
As shown in Figure 2, when needs are observed the healing state of wound, open the window 7 that to open on the semipermeable membrane 4, mobile porous dressing owing to be the adhesive-free area territory, can carry out moving of porous dressing below the window 7 that can open, edge district at semipermeable membrane 4 also can partly be provided with the adhesive-free area territory, when having observed wound, close semipermeable membrane 4, and window 7 sealings that can open on the semipermeable membrane 4.
The manufacturing step that the closed negative pressure drainage of surgical wound of the present invention is filled dressing with wound surface is as follows:
At first, sophisticated vegetable sponge is gone seed, cleaning, drying for standby;
Secondly, vegetable sponge is cut into the shape that matches with the wound surface profile, control its thickness and be no more than 4 centimetres; Shape can be cut into different shape according to clinical needs, as strip, square, circular, oval, triangle etc.;
The 3rd, the vegetable sponge of cutting forming is carried out high-temperature sterilization; Can adopt conventional sterilization method of medical treatment and conventional sterilisation temp to carry out disinfection, sterilisation temp gets final product between 100-150 ℃;
The 4th, under gnotobasis with the sterile vegetable sponge of micropore lining (as silkworm silk gauze, staple gauze or rubber with holes) parcel or be mounted on the upper and lower surface of sterile vegetable sponge;
The 5th, with aseptic vegetable sponge, insert in the aseptic chitin solution and carry out coating;
The 6th, sticked the semipermeable membrane of sealing and fixation at the upper surface of the vegetable sponge that includes poromerics;
The 7th, an end of drainage tube is inserted in the vegetable sponge (also can when clinical use plug-in mounting), also answer liquid supplementation pipe of plug-in mounting in case of necessity.
At last, the vegetable sponge of above-mentioned preparation gained is placed aseptic package bag promptly get and fill dressing based on the wound surface of vegetable sponge.
During use, unpack in the scene, and dressing is covered on the skin incision, and employing can form fills the semipermeable membrane sealing wound surface that dressing moves, and an end of suction catheter is linked to each other with negative pressure source and can start working.
As shown in Figure 1, the closed negative pressure drainage of a kind of surgical wound pastes with the conduit type skin incision, it is mainly by vegetable sponge matrix 1, micropore lining bottom 2, micropore lining surface layer 3, form and fill dressing movably required semipermeable membrane 4 of enclosed cavity and suction catheter 5 compositions, the thickness of vegetable sponge matrix 1 is 3 centimetres, it is between micropore lining bottom 2 and surface layer 3, can be connected to a bag shaped structure around micropore lining bottom 2 and the surface layer 3, can not link to each other mutually yet, the bright zone that the central area of semipermeable membrane 4 can be opened for no glue, three limits are provided with opening, be what seal on one side, opening bright zone like this is convenient to fill dressing and moves the observation wound, the edge district be permeable watertight the adhesivity district arranged, its main effect is the environment that forms a sealing around wound, so that can in the environment of sealing, form negative pressure by negative pressure generator, and then be convenient to wound fluid and see through micropore lining bottom 2 and enter in the vegetable sponge matrix 1, suction catheter from stretch into vegetable sponge matrix 15 sucks in the drainage bottle again, in case of necessity, also can insert feeder current pipe 6 in the vegetable sponge matrix 1, so that be wound surface supplement therapy liquid or nutritional solution by positive pressure system.The semipermeable membrane 4 of sealing usefulness is used for the impermeable plastic wound dressing wound surface, and requirement is not by fluid molecule, to antibacterial certain barrier to be arranged by gaseous molecular, can adopt polyurethane semipermeable membrane commonly used at present.Drainage tube 5 can use single and many drains according to the wound surface situation, buries and fills in vegetable sponge matrix 1 inside, adopts loose structure and needs certain rigidity, can adopt silica gel tube or high molecule plastic pipe.Substitute drainage tube and liquid supplementation pipe with face shield, be attached at the bright zone window, promptly become the mask type skin incision and paste.Negative pressure suction device adopts portable mechanism vacuum suction dish.
During concrete enforcement, described micropore lining is one or more the combination in silkworm silk gauze, staple gauze or the rubber with holes, be the best wherein with the silkworm silk gauze, fibroin in the silkworm silk gauze and human body skin cutin protein structure be similar characteristic very, as vegetable sponge surface coverage or lapping, the fineness that can increase the vegetable sponge surface reaches vegetable sponge surface microporeization (silkworm silk gauze micro-pore diameter is at 0.2-1.0mm), make wound surface granulation growth uniformity, and fibroin can promote the inflammation wound to dwindle, promote the collagen protein secretion.
The part that the present invention does not relate to prior art that maybe can adopt all same as the prior art is realized.
Claims (3)
1. the closed negative pressure drainage of surgical wound is filled the preparation method of dressing with wound surface, and its step is as follows:
At first, sophisticated vegetable sponge is gone seed, cleaning, drying for standby;
Secondly, vegetable sponge is cut into the shape that matches with the wound surface profile, thickness is no more than 4 centimetres;
The 3rd, with micropore lining parcel vegetable sponge or be mounted on the upper and lower surface of vegetable sponge;
The 4th, the vegetable sponge that is shaped is carried out the high temperature and high pressure steam sterilization, the filling dressing after the sterilization is preserved moisture;
The 5th, with aseptic vegetable sponge, insert in aseptic chitin solution or the silver ion solution and carry out coating;
At last, the vegetable sponge of above-mentioned preparation gained is placed aseptic package bag promptly get and fill dressing based on the wound surface of vegetable sponge.
2. according to the described preparation method of claim 1, it is characterized in that: described step comprises and will fix in the end insertion vegetable sponge of drainage tube, liquid supplementation pipe and by suture.
3. according to the described preparation method of claim 1, it is characterized in that: comprise forming and fill the movably preparation method of the required semipermeable membrane of enclosed cavity of dressing, the steps include:
(1) middle section of semipermeable membrane is set to not have the window that glue can be opened, and is provided with mounted and removable sealing paste at the opening part of the window that can open;
What (2) the edge district of semipermeable membrane was set to permeable watertight has an adhesivity district.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110148013 CN102284124A (en) | 2011-06-02 | 2011-06-02 | Preparation method of wound surface filling dressing for surgical wound surface vacuum sealing drainage |
| DE212011100178U DE212011100178U1 (en) | 2010-12-06 | 2011-11-22 | Dressing for vacuum seal drainage in surgical wound and drainage device |
| PCT/CN2011/082578 WO2012075882A1 (en) | 2010-12-06 | 2011-11-22 | Wound dressing for surgical wound vacuum-assisted closure and preparation method therefor and device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110148013 CN102284124A (en) | 2011-06-02 | 2011-06-02 | Preparation method of wound surface filling dressing for surgical wound surface vacuum sealing drainage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102284124A true CN102284124A (en) | 2011-12-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110148013 Pending CN102284124A (en) | 2010-12-06 | 2011-06-02 | Preparation method of wound surface filling dressing for surgical wound surface vacuum sealing drainage |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2769845C1 (en) * | 2021-08-02 | 2022-04-07 | Владимир Владимирович Федюшкин | Method for drainage of sutured wounds of various localization |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2329127A (en) * | 1997-09-12 | 1999-03-17 | Kci Medical Ltd | Suction head and drape wound treatment assembly |
| CN101257938A (en) * | 2005-09-07 | 2008-09-03 | 泰科保健集团有限合伙公司 | Wound dressing with vacuum reservoir |
| CN102038575A (en) * | 2010-12-06 | 2011-05-04 | 陈德华 | Wound filling dressing for closed negative pressure drainage of surgical wound as well as preparation method |
-
2011
- 2011-06-02 CN CN 201110148013 patent/CN102284124A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2329127A (en) * | 1997-09-12 | 1999-03-17 | Kci Medical Ltd | Suction head and drape wound treatment assembly |
| US20050028828A1 (en) * | 1997-09-12 | 2005-02-10 | Kci Licensing, Inc. | Surgical drape and suction head for wound treatment |
| CN101257938A (en) * | 2005-09-07 | 2008-09-03 | 泰科保健集团有限合伙公司 | Wound dressing with vacuum reservoir |
| CN102038575A (en) * | 2010-12-06 | 2011-05-04 | 陈德华 | Wound filling dressing for closed negative pressure drainage of surgical wound as well as preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2769845C1 (en) * | 2021-08-02 | 2022-04-07 | Владимир Владимирович Федюшкин | Method for drainage of sutured wounds of various localization |
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Application publication date: 20111221 |