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CN102247511B - High-efficiency burn and scald medicine and preparation method thereof - Google Patents

High-efficiency burn and scald medicine and preparation method thereof Download PDF

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CN102247511B
CN102247511B CN 201010598700 CN201010598700A CN102247511B CN 102247511 B CN102247511 B CN 102247511B CN 201010598700 CN201010598700 CN 201010598700 CN 201010598700 A CN201010598700 A CN 201010598700A CN 102247511 B CN102247511 B CN 102247511B
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陈国英
刘沙
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Abstract

本发明涉及一种高效烧烫伤药及其制备方法,所述的高效烧烫伤药包含茶油3~7份、芦荟皮7~15份等成分,本发明利用热乙醇进行芦荟大黄素的提取,充分利用回收的芦荟皮制成所述的高效烧烫伤药,本发明还包含绿豆4~12份、冰片2~5份,能有效治疗中/轻度的烫伤,消炎能力强,清热解毒、滋润皮肤,促进创伤面的愈合,愈合后不留疤痕。The invention relates to a high-efficiency burn and scald medicine and a preparation method thereof. The high-efficiency burn and scald medicine contains 3-7 parts of camellia oil, 7-15 parts of aloe bark and other components. The invention uses hot ethanol to extract aloe-emodin, The high-efficiency burn and scald medicine is made by making full use of recovered aloe bark. The present invention also contains 4-12 parts of mung bean and 2-5 parts of borneol, which can effectively treat moderate/mild burns, have strong anti-inflammatory ability, clear away heat, detoxify, and moisturize Skin, promote the healing of the wound surface, leaving no scars after healing.

Description

一种高效烧烫伤药及其制备方法A kind of high-efficiency burn and scald medicine and preparation method thereof

技术领域 technical field

本发明涉及一种烫伤药,尤其涉及一种高效烫伤药及其制备方法。 The invention relates to a scald medicine, in particular to a high-efficiency scald medicine and a preparation method thereof.

背景技术 Background technique

芦荟是一种营养价值很高的食品,它广泛应用于医药、食品以及化妆品等各个领域,不管用于哪个领域,基本都是需要去皮的,也就是说芦荟皮的数量其实是非常大的。但是目前芦荟皮的利用率非常低,仅有少量的商家把芦荟皮进行粉碎等简易操作,用于做肥料等用途,没有实在地针对芦荟皮所包含的物质进行科学的利用和合理的提取,无法发挥其主要的作用,浪费了很好的资源,此外,单纯的芦荟皮即使研成粉末,因为营养的单一和本身具备一定的刺激性,也不容易被吸收和利用,总而言之,芦荟皮所包含的营养没有被科学地利用起来,这是一种资源的浪费和财富的损失,不符合现代环保的概念。 Aloe vera is a food with high nutritional value. It is widely used in various fields such as medicine, food and cosmetics. No matter which field it is used in, it basically needs to be peeled, which means that the number of aloe vera skins is actually very large. . However, the utilization rate of aloe bark is very low at present, and only a small number of businesses carry out simple operations such as crushing aloe bark for fertilizers and other purposes, and there is no real scientific utilization and reasonable extraction of the substances contained in aloe bark. Can't bring into play its main effect, wasting very good resources, in addition, even if pure aloe vera skin is researched into powder, because the nutrition is single and itself possesses certain stimulation, also not easy to be absorbed and utilized, in a word, aloe vera skin The nutrients contained in it have not been used scientifically, which is a waste of resources and loss of wealth, which does not conform to the concept of modern environmental protection.

发明内容 Contents of the invention

为了克服现有技术的不足,本发明充分利用芦荟皮所包含的营养,并进行科学合理的搭配,从而提供一种高效烧烫伤药,包含如下重量比的成分:茶油3~7份,芦荟皮7~15份。 In order to overcome the deficiencies in the prior art, the present invention makes full use of the nutrition contained in the aloe bark, and carries out scientific and rational collocation, thereby providing a kind of high-efficiency burn and scald medicine, comprising the following ingredients in weight ratio: tea oil 3~7 parts, aloe vera Skin 7~15 parts.

其中,芦荟皮中含有有效成分芦荟大黄素,有关研究表明,芦荟皮含有的芦荟大黄素为0.4%,芦荟大黄素作为大黄的抗菌有效成分,可从芦荟皮中提取,具有抗肿瘤活性、抗菌活性和免疫抑制作用,芦荟大黄素对烫伤具有较好的疗效;当然,仅仅只有芦荟大黄素,成分太单一,对烫伤的疗效也会有所折扣,因此,本发明还包含茶油等成分。 Among them, the aloe-emodin contains the active ingredient aloe-emodin, relevant research shows that the aloe-emodin contained in the aloe-emodin is 0.4%. Activity and immunosuppressive effect, aloe-emodin has a better curative effect on scald; of course, only aloe-emodin, the composition is too single, the curative effect on scald will also be reduced to some extent, therefore, the present invention also includes ingredients such as camellia oil.

茶油是山茶果提炼而成的食用油,又名油茶籽。茶油整个生长过程中不施农药、化肥等,不含芥酸、胆固醇、黄曲霉素等对人体有害物质。茶油色泽金黄或浅黄,品质纯净,澄清透明,气味清香,味道纯正,是中国政府提倡推广的纯天然木本食用植物油,也是国际粮农组织首推的卫生保健植物食用油。茶油具有清热化湿、杀虫解毒等作用,常用于痧气腹痛、疥癣、汤伤,并具有良好的稳定性和抗氧化性,保质期长,易于消化吸收。茶油中单不饱和脂肪酸的含量超过橄榄油,单不饱和脂肪酸的含量高达80%,同时富含较高的维生素E,是橄榄油的两倍,此外还含有角鲨烯与黄酮类物质,对抗癌、抗炎有着极佳的作用;利用茶油与芦荟皮所制成的高效烫伤药能快速杀菌,消炎能力强,促进烧烫伤面的快速愈合,滋润修复肌肤,不留疤痕。此法所致的高效烧烫伤药用于治疗二度及以下的中/轻度烧烫伤,治愈时间为2~6天,治愈率为97%。 Camellia oil is edible oil extracted from camellia fruit, also known as camellia seed. No pesticides, chemical fertilizers, etc. are applied during the whole growth process of camellia oil, and it does not contain erucic acid, cholesterol, aflatoxin and other harmful substances to the human body. Camellia oil is golden or light yellow in color, pure in quality, clear and transparent, with a delicate smell and pure taste. It is a pure natural woody edible vegetable oil promoted by the Chinese government, and also a health-care vegetable edible oil recommended by the International Food and Agriculture Organization. Camellia oil has the functions of clearing heat and dampness, killing insects and detoxifying, etc. It is often used for abdominal pain, mange, and soup injury. It has good stability and anti-oxidation, long shelf life, and is easy to digest and absorb. The content of monounsaturated fatty acid in camellia oil exceeds that of olive oil, the content of monounsaturated fatty acid is as high as 80%, and it is rich in vitamin E, which is twice that of olive oil. In addition, it also contains squalene and flavonoids. It has excellent anti-cancer and anti-inflammatory effects; the high-efficiency scald medicine made of tea oil and aloe vera skin can quickly sterilize bacteria, has strong anti-inflammatory ability, promotes the rapid healing of burns and scalds, moisturizes and repairs the skin, and leaves no scars. The high-efficiency burn and scald medicine caused by this method is used to treat moderate/slight burns of the second degree and below. The healing time is 2 to 6 days, and the cure rate is 97%.

为了进一步实现所述的高效烧烫伤药,所述的高效烫伤药还包含如下重量比的成分:绿豆4~12份,冰片2~5份。绿豆性味甘凉,有清热解毒的作用;冰片,又名片脑、桔片等,是龙脑香科植物龙脑香的树脂和挥发油加工品提取获得的结晶,近乎于纯粹的右旋龙脑,可用于用于闭证神昏、目赤肿痛、喉痹口疮、疮疡肿痛、溃后不敛等,冰片经粘膜和皮下组织均很容易被吸收,结合绿豆和冰片的作用,能更为高效的治愈烧烫创口,解毒杀菌,使得烧烫伤面的愈合更为快速、有效。 In order to further realize the high-efficiency burn and scald medicine, the high-efficiency scald medicine also includes the following components by weight: 4-12 parts of mung beans, and 2-5 parts of borneol. Mung bean is sweet and cool in nature and has the effect of clearing away heat and detoxification; Borneol, also known as sliced brain, orange slice, etc., is the crystallization obtained from the resin and volatile oil processing products of dipterocarp, which is almost pure D-borneol , can be used for closed-syndrome coma, red eyes and swelling pain, sore throat, sore swelling and pain, ulcer after ulceration, etc. Borneol is easily absorbed through the mucous membrane and subcutaneous tissue, combined with mung bean and Borneol, can More efficient healing of burns and scalds, detoxification and sterilization, making the healing of burns and scalds faster and more effective.

为了进一步实现所述的高效烧烫伤药,所述的高效烧烫伤药包含的各成分重量比如下:茶油6份,芦荟皮13份,绿豆12份,冰片3份,此比例的成分配置高效烧烫伤药,非常适合用于治疗二度及以下的中/轻度烧烫伤,治愈时间为2~4天,治愈率为98%。 In order to further realize the described high-efficiency burn and scald medicine, the weight ratio of each component contained in the high-efficiency burn and scald medicine is as follows: 6 parts of camellia oil, 13 parts of aloe bark, 12 parts of mung beans, and 3 parts of borneol. Burn and scald medicine, very suitable for the treatment of second-degree and below moderate/slight burns and scalds, the healing time is 2-4 days, and the healing rate is 98%.

本发明还提供上述高效烧烫伤药的制备方法,所述的制备方法包含如下步骤: The present invention also provides a preparation method of the above-mentioned high-efficiency burn and scald medicine, the preparation method comprising the following steps:

A、取芦荟皮洗净搅碎,加入浓度为60~65%的乙醇10~25份以及水8~16份,搅拌至少3min,搅拌的速度控制为1800~2000r/min,得到混合液; A. Take the aloe bark and wash it and crush it, add 10-25 parts of ethanol with a concentration of 60-65% and 8-16 parts of water, stir for at least 3 minutes, and control the stirring speed at 1800-2000r/min to obtain a mixed solution;

B、对步骤A所得的混合液进行过滤,取得滤液,对所得的滤液进行加热和搅拌操作,所述的加热和搅拌操作同时进行,搅拌速度控制为1200~2400r/min,加热直至45~49℃, 并保持该温度范围5~25min,得到芦荟皮精华; B. Filter the mixed solution obtained in step A, obtain the filtrate, heat and stir the obtained filtrate, the heating and stirring operations are carried out simultaneously, the stirring speed is controlled at 1200 ~ 2400r/min, and heated until 45 ~ 49 ℃, and maintain the temperature range for 5~25min to obtain aloe bark essence;

C、将茶油加热并保持温度在50~60℃,加入步骤B所得的芦荟皮精华并进行搅拌,搅拌速度控制为1200~2400r/min,搅拌持续6~10min。 C. Heat the camellia oil and keep the temperature at 50-60°C, add the aloe bark essence obtained in step B and stir, the stirring speed is controlled at 1200-2400r/min, and the stirring lasts for 6-10min.

芦荟大黄素为大黄抗菌的有效成分,可从芦荟皮中提取,具有抗肿瘤活性、抗菌活性和免疫抑制等作用,对烫伤有较好的疗效,芦荟大黄素易溶于热乙醇里面;将芦荟皮洗净搅碎,搅碎芦荟皮有助于增大芦荟皮与乙醇的接触面积,促进其有效成分的溶解,加入浓度为60~65%的乙醇10~25份以及水8~16份,搅拌至少3min,搅拌的速度控制为1800~2000r/min,得到混合液,然后将所得的混合液进行过滤,取得滤液,对所得的滤液进行加热和搅拌操作,所述的加热和搅拌操作同时进行,搅拌速度控制为1200~2400r/min,加热直至45~49℃, 并保持该温度范围5~25min,此过程能有效得到芦荟皮精华,即主要为芦荟大黄素的芦荟精华,同时还能促进乙醇的挥发,防止刺激皮肤,得到温和的芦荟皮精华。 Aloe-emodin is the antibacterial active ingredient of rhubarb, which can be extracted from aloe bark. It has anti-tumor activity, antibacterial activity and immunosuppressive effects, and has good curative effect on burns. Aloe-emodin is easily soluble in hot ethanol; Wash and crush the skin, crushing the aloe skin helps to increase the contact area between the aloe skin and ethanol, and promote the dissolution of its active ingredients. Add 10-25 parts of ethanol with a concentration of 60-65% and 8-16 parts of water. Stir for at least 3 minutes, control the stirring speed to 1800~2000r/min, obtain the mixed solution, then filter the obtained mixed solution to obtain the filtrate, heat and stir the obtained filtrate, and perform the heating and stirring operations simultaneously , the stirring speed is controlled at 1200~2400r/min, heated up to 45~49°C, and kept in this temperature range for 5~25min, this process can effectively obtain the aloe skin essence, that is, the aloe essence mainly composed of aloe-emodin, and at the same time promote The volatilization of ethanol prevents the skin from being irritated, and a mild aloe vera skin essence is obtained.

将茶油加热并保持温度在50~60℃,加入步骤B所得的芦荟皮精华并进行搅拌,搅拌速度控制为1200~2400r/min,搅拌持续6~10min,使得芦荟精华与茶油充分混合,并将余量的乙醇挥发完全,使之更为切合人体的皮肤,不刺激。 Heat the camellia oil and keep the temperature at 50~60°C, add the aloe bark essence obtained in step B and stir, the stirring speed is controlled at 1200~2400r/min, and the stirring lasts for 6~10min, so that the aloe essence and camellia oil are fully mixed, And the remaining ethanol is completely volatilized to make it more suitable for human skin without irritation.

为了进一步实现上述的高效烧烫伤药的制备方法,所述的步骤B还包含绿豆研粉操作,取所述的绿豆研磨成绿豆粉;所述的步骤C将茶油加热并保持温度在50~60℃,加入步骤B所得的芦荟皮精华和绿豆粉,进行搅拌,搅拌速度控制为1200~2400r/min,搅拌持续6~10min后,加入所述的冰片,搅拌均匀。此法制得的高效烧烫伤药,用于治疗二度及以下的中/轻度烧烫伤效果非常明显,愈合速度快,不留疤。 In order to further realize the preparation method of the above-mentioned high-efficiency burn and scald medicine, the step B also includes the mung bean grinding operation, and the mung bean is ground into mung bean powder; the step C is to heat the tea oil and keep the temperature at 50~ 60°C, add the aloe bark essence and mung bean powder obtained in step B, and stir, the stirring speed is controlled at 1200~2400r/min, after stirring for 6~10min, add the borneol, and stir evenly. The high-efficiency burn and scald medicine prepared by this method is very effective in treating second-degree and below moderate/slight burns and scalds, with fast healing speed and no scars.

为了进一步实现上述的高效烧烫伤药的制备方法,所述步骤B保持在45~49℃范围内8~12min,适当加长步骤B的加热时间,能使得乙醇挥发完全,保护烧烫伤口,促进其愈合。 In order to further realize the preparation method of the above-mentioned high-efficiency burn and scald medicine, the step B is kept in the range of 45-49°C for 8-12 minutes, and the heating time of step B is appropriately lengthened to completely volatilize the ethanol, protect the burn and scald wound, and promote its heal.

本发明的有益效果是:提供一种高效烧烫伤药及其制备方法,所述的高效烧烫伤药包含茶油3~7份、芦荟皮7~15份等成分,本发明利用热乙醇进行芦荟大黄素的提取,充分利用回收的芦荟皮制成所述的高效烧烫伤药,本发明还包含绿豆4~12份、冰片2~5份,能有效治疗中/轻度的烫伤,消炎能力强,清热解毒、滋润皮肤,促进创伤面的愈合,愈合后不留疤痕。 The beneficial effects of the present invention are: provide a high-efficiency burn and scald medicine and its preparation method, the high-efficiency burn and scald medicine contains 3~7 parts of camellia oil, 7~15 parts of aloe bark and other ingredients, the present invention uses hot ethanol to process aloe Extraction of emodin, making full use of recovered aloe bark to make the high-efficiency burn and scald medicine, the present invention also contains 4-12 parts of mung beans and 2-5 parts of borneol, which can effectively treat moderate/slight burns and has strong anti-inflammatory ability , clear away heat and detoxify, moisturize the skin, promote the healing of the wound surface, and leave no scars after healing.

附图说明 Description of drawings

无图。 no picture.

具体实施方式 Detailed ways

下面结合较佳实施例详细说明本发明的具体实施方式。 The specific implementation of the present invention will be described in detail below in conjunction with preferred embodiments.

实施例1: Example 1:

烫伤药利用如下重量比的成分配置:茶油3份、芦荟皮7份。 The scald medicine utilizes the following components by weight to configure: 3 parts of camellia oil and 7 parts of aloe bark.

使用本例治疗二度及以下的轻度烫伤,治愈时间为2~6天,治愈率为97%,烧烫伤口不留疤痕。 Using this example to treat mild burns of the second degree and below, the healing time is 2 to 6 days, the healing rate is 97%, and no scars are left on the scalded wound.

实施例2: Example 2:

烫伤药利用如下重量比的成分配置:茶油7份、芦荟皮15份。 The scald medicine utilizes the following components by weight to configure: 7 parts of camellia oil and 15 parts of aloe bark.

使用本例治疗二度及以下的轻度烫伤,治愈时间为2~4天,治愈率为97%,烧烫伤口不留疤痕。 Using this example to treat mild burns of the second degree and below, the healing time is 2 to 4 days, the healing rate is 97%, and no scars are left on the scalded wound.

实施例3: Example 3:

烫伤药利用如下重量比的成分配置:茶油6份,芦荟皮13份,绿豆12份,冰片3份。 The scald medicine utilizes the following composition by weight ratio: 6 parts of camellia oil, 13 parts of aloe bark, 12 parts of mung bean, and 3 parts of borneol.

使用本例治疗二度及以下的轻度烫伤,治愈时间为2~4天,治愈率为98%,烧烫伤口不留疤痕。 Using this example to treat mild burns of the second degree and below, the healing time is 2 to 4 days, the healing rate is 98%, and no scars are left on the burned wound.

实施例4: Example 4:

烫伤药利用如下重量比的成分配置:茶油6份,芦荟皮13份,绿豆12份,冰片3份。将上述成分进行芦荟皮提取精华、药材研粉以及制膏等步骤,其中,包含的具体步骤如下: The scald medicine utilizes the following composition by weight ratio: 6 parts of camellia oil, 13 parts of aloe bark, 12 parts of mung bean, and 3 parts of borneol. The above-mentioned ingredients are subjected to the steps of extracting the essence of aloe bark, grinding medicinal materials and making ointment, among which, the specific steps involved are as follows:

A、取芦荟皮洗净搅碎,加入浓度为60%的乙醇10份以及水8份,搅拌3min,搅拌的速度控制为1800r/min,得到混合液; A, get the aloe bark and wash it and grind it into pieces, add 10 parts of ethanol and 8 parts of water with a concentration of 60%, stir for 3 minutes, and control the speed of stirring to 1800r/min to obtain a mixed solution;

B、对步骤A所得的混合液进行过滤,取得滤液,对所得的滤液进行加热和搅拌操作,所述的加热和搅拌操作同时进行,搅拌速度控制为2400r/min,加热直至45~49℃, 并保持该温度范围10min,得到芦荟皮精华;取所述的绿豆研磨成绿豆粉; B. Filter the mixed solution obtained in step A, obtain the filtrate, and heat and stir the obtained filtrate. The heating and stirring operations are carried out simultaneously, and the stirring speed is controlled at 2400r/min, and heated until 45~49°C. And keep the temperature range for 10 minutes to obtain the aloe bark essence; take the mung beans and grind them into mung bean powder;

C、将茶油加热并保持温度在50~60℃,加入步骤B所得的芦荟皮精华和绿豆粉并进行搅拌,搅拌速度控制为1200r/min,搅拌持续12min后,加入所述的冰片,搅拌均匀。 C. Heat the camellia oil and keep the temperature at 50~60°C, add the aloe bark essence and mung bean powder obtained in step B and stir, the stirring speed is controlled at 1200r/min, after stirring for 12min, add the borneol and stir uniform.

使用本例治疗二度及以下的轻度烫伤,治愈时间为2~4天,治愈率为98%,烧伤伤口不留疤痕。 Using this example to treat mild burns of the second degree and below, the healing time is 2 to 4 days, the healing rate is 98%, and the burn wound does not leave scars.

以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明,不能认定本发明的具体实施只局限于这些说明。对于本发明所属技术领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干简单推演或替换,都应当视为属于本发明的保护范围。 The above content is a further detailed description of the present invention in conjunction with specific preferred embodiments, and it cannot be assumed that the specific implementation of the present invention is limited to these descriptions. For those of ordinary skill in the technical field of the present invention, without departing from the concept of the present invention, some simple deduction or replacement can be made, which should be regarded as belonging to the protection scope of the present invention.

Claims (3)

1. a high-efficiency burn treating medicine is characterized in that, is by 6 parts of Oleum Camelliae, 13 parts of aloe skins, and 12 parts in Semen phaseoli radiati, 3 parts of Borneolum Syntheticums are made.
2. the preparation method of high-efficiency burn treating medicine according to claim 1 is characterized in that, described preparation method comprises following steps:
A, get aloe skin and clean and to blend, add concentration and be 8 ~ 16 parts in 60 ~ 65% 10 ~ 25 parts of ethanol and water, stir at least 3min, the speed controlling of stirring is 1800 ~ 2000r/min, obtains mixed liquor;
B, the mixed liquor of steps A gained is filtered, obtain filtrate, the filtrate of gained is heated and stirring operation, described heating and stirring operation carry out simultaneously, mixing speed is controlled to be 1200 ~ 2400r/min, heating is until 45 ~ 49 ℃, and keeps this temperature range 5 ~ 25min, obtains the aloe skin elite; This step also comprises the operation of Semen phaseoli radiati levigation, gets described Semen phaseoli radiati and grinds to form Semen phaseoli radiati powder;
C, with Oleum Camelliae heating and maintain the temperature at 50 ~ 60 ℃, the aloe skin elite and the Semen phaseoli radiati powder that add step B gained also stir, mixing speed is controlled to be 1200 ~ 2400r/min, stirs to continue 6 ~ 10min, adds described Borneolum Syntheticum, stirs.
3. the preparation method of high-efficiency burn treating medicine according to claim 2 is characterized in that, described step B remains on 8 ~ 12min in 45 ~ 49 ℃ of scopes.
CN 201010598700 2010-12-21 2010-12-21 High-efficiency burn and scald medicine and preparation method thereof Expired - Fee Related CN102247511B (en)

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