CN102078558A - Pharmaceutical composition for treating cough and preparation method thereof - Google Patents
Pharmaceutical composition for treating cough and preparation method thereof Download PDFInfo
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- CN102078558A CN102078558A CN2009102164024A CN200910216402A CN102078558A CN 102078558 A CN102078558 A CN 102078558A CN 2009102164024 A CN2009102164024 A CN 2009102164024A CN 200910216402 A CN200910216402 A CN 200910216402A CN 102078558 A CN102078558 A CN 102078558A
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- parts
- pharmaceutical composition
- cough
- crude drug
- powder
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- 206010011224 Cough Diseases 0.000 title claims abstract description 37
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 239000003814 drug Substances 0.000 claims abstract description 22
- 239000000843 powder Substances 0.000 claims description 17
- 229940079593 drug Drugs 0.000 claims description 16
- 239000006187 pill Substances 0.000 claims description 7
- 241000209128 Bambusa Species 0.000 claims description 6
- 235000014435 Mentha Nutrition 0.000 claims description 6
- 241001072983 Mentha Species 0.000 claims description 6
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 6
- 235000012239 silicon dioxide Nutrition 0.000 claims description 6
- 239000003826 tablet Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 3
- 238000002481 ethanol extraction Methods 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims description 2
- 239000000706 filtrate Substances 0.000 claims description 2
- -1 filter Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 3
- 244000141331 Amomum villosum Species 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 240000003582 Platycodon grandiflorus Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 241000157352 Uncaria Species 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition for treating cough and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The technical problem solved by the invention is that the invention provides a pharmaceutical composition that can effectively treat cough. The pharmaceutical composition for treating cough of the present invention comprises, by weight, the following raw materials: 30-40 parts of uncaria, 40-50 parts of tabasheer, 10-15 parts of balloonflower, 50-60 parts of amomum villosum, 50-60 parts of tangerine peel, 10-15 parts of poria cocos, 50-60 parts of mint, 20-25 parts of licorice, and 7-9 parts of calculus bovis. The pharmaceutical composition for treating cough of the present invention has good efficacy for treating cough and has no significant toxic and side effects; the invention provides a new selection to medicine for treating cough and has wide application prospects.
Description
Technical field
The present invention relates to pharmaceutical composition for the treatment of cough and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Cough is one of cardinal symptom of respiratory system disease.Cough but no phlegm or amount of expectoration are dry cough seldom, are common in acute pharyngolaryngitis, bronchitic initial stage; Foreign body in the bronchus is more common in the acute cough that takes place suddenly; Long-term chronic cough is more common in chronic bronchitis, pulmonary tuberculosis etc.
If not treatment in time, or malpractice, cough may be diffused into contiguous bronchia to the trachea pathological changes, aggravates disease.In addition, lasting violent cough also can influence rest, and easy consumption muscle power, and the destruction that can cause the alveolar wall Elastic tissue are brought out emphysema.
Summary of the invention
Technical problem to be solved by this invention provides a kind of pharmaceutical composition that can effectively treat cough.
The present invention treats the pharmaceutical composition of cough, and the weight proportion of its crude drug is as follows: 30～40 parts of Ramulus Uncariae Cum Uncis, 40～50 parts of Concretio Silicea Bambusaes, 10～15 parts of Radix Platycodoniss; 50～60 parts of Fructus Amomis, 50～60 parts of Pericarpium Citri Reticulataes, 10～15 parts in Poria; 50～60 parts of Herba Menthaes, 20～25 parts in Radix Glycyrrhizae, 7～9 parts of Calculus Boviss.
Further; the present invention treats the pharmaceutical composition of cough; the weight proportion of its crude drug is preferably as follows: 32～38 parts of Ramulus Uncariae Cum Uncis, 41～46 parts of Concretio Silicea Bambusaes, 12～15 parts of Radix Platycodoniss; 50～55 parts of Fructus Amomis; 52～58 parts of Pericarpium Citri Reticulataes, 11～14 parts in Poria, 52～58 parts of Herba Menthaes; 21～24 parts in Radix Glycyrrhizae, 7～9 parts of Calculus Boviss.
Further, the present invention treats the pharmaceutical composition of cough, and the weight proportion of its crude drug is most preferably as follows: 35 parts of Ramulus Uncariae Cum Uncis, 43 parts of Concretio Silicea Bambusaes, 13 parts of Radix Platycodoniss, 53 parts of Fructus Amomis, 55 parts of Pericarpium Citri Reticulataes, 13 parts in Poria, 55 parts of Herba Menthaes, 22 parts in Radix Glycyrrhizae, 8 parts of Calculus Boviss.
The dosage form that the present invention treats the pharmaceutical composition of cough can be a regular dosage form, as: tablet, granule, capsule, powder or pill.
The present invention also provides the method for the pharmaceutical composition for preparing above-mentioned treatment cough; this method is: get each crude drug by weight ratio; Calculus Bovis is ground to form fine powder; all the other crude drug are ground into fine powder; mixing; add appropriate amount of auxiliary materials, technology makes tablet, granule, capsule, powder or pill routinely.
Further, the pharmaceutical composition for preparing above-mentioned treatment cough, can also adopt following method: get each crude drug by weight ratio, Calculus Bovis is ground to form fine powder, all the other crude drug concentration are the ethanol extraction 1～3 time of 70～80wt%, extract 3～24h at every turn, filter, filtrate is concentrated, dry, obtains extractum; With Calculus Bovis fine powder and extractum mixing, add appropriate amount of auxiliary materials, technology makes tablet, granule, capsule, powder or pill routinely.
The present invention treats that the effect of medicine composite for curing cough of cough is better, and cure rate can reach more than 95%, and said composition does not have obvious toxic-side effects, and the present invention has broad application prospects for the medicine of treatment cough provides a kind of new selection.
The specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is further described, does not therefore limit the present invention among the described scope of embodiments.
The preparation of embodiment medicine of the present invention
Press the proportioning of table 1, Calculus Bovis is ground to form fine powder, all the other crude drug are ground into fine powder, and mixing, every 100g powder add refined honey 100g and make big honeyed pills.
The proportioning of each crude drug of table 1
The test example
The medicine of the present invention of embodiment 1 preparation is used for the treatment of cough, through 231 routine clinical observations (No. 1 prescription 51 examples, No. 2 prescription 60 examples, No. 3 prescription 60 examples, No. 4 prescription 60 examples), total cure rate all reaches more than 95%, wherein No. 1 prescribed treatment cough cure rate is 96%, No. 2 prescribed treatment cough cure rates are that 97%, No. 3 prescribed treatment cough cure rate is that 97%, No. 4 prescribed treatment cough cure rate is 99%.
Claims (6)
1. treat the pharmaceutical composition of cough, it is characterized in that: the weight proportion of its crude drug is as follows: 30～40 parts of Ramulus Uncariae Cum Uncis, 40～50 parts of Concretio Silicea Bambusaes, 10～15 parts of Radix Platycodoniss; 50～60 parts of Fructus Amomis, 50～60 parts of Pericarpium Citri Reticulataes, 10～15 parts in Poria; 50～60 parts of Herba Menthaes, 20～25 parts in Radix Glycyrrhizae, 7～9 parts of Calculus Boviss.
2. the pharmaceutical composition of treatment cough according to claim 1; it is characterized in that: the weight proportion of its crude drug is as follows: 32～38 parts of Ramulus Uncariae Cum Uncis; 41～46 parts of Concretio Silicea Bambusaes; 12～15 parts of Radix Platycodoniss, 50～55 parts of Fructus Amomis, 52～58 parts of Pericarpium Citri Reticulataes; 11～14 parts in Poria; 52～58 parts of Herba Menthaes, 21～24 parts in Radix Glycyrrhizae, 7～9 parts of Calculus Boviss.
3. the pharmaceutical composition of treatment cough according to claim 2, it is characterized in that: the weight proportion of its crude drug is as follows: 35 parts of Ramulus Uncariae Cum Uncis, 43 parts of Concretio Silicea Bambusaes, 13 parts of Radix Platycodoniss; 53 parts of Fructus Amomis, 55 parts of Pericarpium Citri Reticulataes, 13 parts in Poria; 55 parts of Herba Menthaes, 22 parts in Radix Glycyrrhizae, 8 parts of Calculus Boviss.
4. according to the pharmaceutical composition of each described treatment cough of claim 1～3, it is characterized in that: the dosage form of described pharmaceutical composition is tablet, granule, capsule, powder or pill.
5. the method for preparing the pharmaceutical composition of the described treatment cough of claim 4; it is characterized in that: get each crude drug by weight ratio; Calculus Bovis is ground to form fine powder; all the other crude drug are ground into fine powder; mixing; add appropriate amount of auxiliary materials, technology makes tablet, granule, capsule, powder or pill routinely.
6. the method for preparing the pharmaceutical composition of the described treatment cough of claim 4, it is characterized in that: get each crude drug by weight ratio, Calculus Bovis is ground to form fine powder, all the other crude drug concentration are the ethanol extraction 1～3 time of 70～80wt%, each 3～24h that extracts, filter, filtrate is concentrated, dry, obtains extractum; With Calculus Bovis fine powder and extractum mixing, add appropriate amount of auxiliary materials, technology makes tablet, granule, capsule, powder or pill routinely.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102164024A CN102078558A (en) | 2009-11-27 | 2009-11-27 | Pharmaceutical composition for treating cough and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102164024A CN102078558A (en) | 2009-11-27 | 2009-11-27 | Pharmaceutical composition for treating cough and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102078558A true CN102078558A (en) | 2011-06-01 |
Family
ID=44084884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102164024A Pending CN102078558A (en) | 2009-11-27 | 2009-11-27 | Pharmaceutical composition for treating cough and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102078558A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432490A (en) * | 2013-08-08 | 2013-12-11 | 海安常大技术转移中心有限公司 | Traditional Chinese medicine composition for treating cough |
| CN105596695A (en) * | 2016-01-05 | 2016-05-25 | 扎拉嘎白乙拉 | Mongolian medicine Oxytropis antitussive powder |
-
2009
- 2009-11-27 CN CN2009102164024A patent/CN102078558A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432490A (en) * | 2013-08-08 | 2013-12-11 | 海安常大技术转移中心有限公司 | Traditional Chinese medicine composition for treating cough |
| CN103432490B (en) * | 2013-08-08 | 2015-02-25 | 海安常大技术转移中心有限公司 | Traditional Chinese medicine composition for treating cough |
| CN105596695A (en) * | 2016-01-05 | 2016-05-25 | 扎拉嘎白乙拉 | Mongolian medicine Oxytropis antitussive powder |
| CN105596695B (en) * | 2016-01-05 | 2021-04-20 | 扎拉嘎白乙拉 | Mongolian medicine echinocandin cough powder |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110601 |