Summary of the invention
To the deficiency of prior art, the purpose of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, function is different, mouthfeel is good, be prone to serial donkey-hide gelatin product of clothes for a long time and preparation method thereof.The remarkable result that these series of products have the beneficial gas of making light of one's life by commiting suicide, antitoxic heart-soothing and sedative, promote longevity can satisfy the needs of different crowd.
Technical scheme of the present invention is: the oral donkey-hide gelatin series of products of function, form by following feedstock production, and be weight portion: donkey-hide gelatin 10-50 part, functional mass extract 800-1200 part.
The oral donkey-hide gelatin series of products of aforesaid function, preferred scheme is that donkey-hide gelatin is got 25-40 part, functional mass extract 900-1000 part.
The oral donkey-hide gelatin series of products of aforesaid function, preferably scheme is, and said functional mass extract is to get A or the said raw material of B, adds water 1500-2200 part, decocts 20-45 minute, and filtrating concentrates and gets, and is weight portion:
A, Poria cocos 15-25 part, American Ginseng 8-15 part, Chinese yam 15-25 part, arillus longan 4-10 part, matrimony vine 8-12 part, dried orange peel 4-8 part, hawthorn 4-8 part, date 8-15 part;
B, Poria cocos 13-17 part, citron 8-12 part, Buddha's hand 8-12 part, Chinese yam 12-17 part, fructus amomi 4-8 part, peppermint 4-8 part, matrimony vine 6-12 part, dried orange peel 2-6 part, hawthorn 2-6 part, date 6-10 part.
More preferred, each raw material is among the said A: 20 parts in Poria cocos, 10 parts of American Ginsengs, 20 parts of Chinese yams, 6 parts of arillus longans, 10 parts of matrimony vines, 6 parts of dried orange peels, 6 parts of hawthorn, 10 parts in date; Each raw material is among the said B: 15 parts in Poria cocos, 10 parts of citrons, 15 parts of 10 portions of Chinese yams of Buddha's hand, 6 parts of fructus amomis, 6 parts of peppermints, 8 parts of matrimony vines, 4 parts of dried orange peels, 4 parts of hawthorn, 8 parts in date.
The oral donkey-hide gelatin series of products of aforementioned functional, preferred scheme is also to comprise sweet substance 10-50 part in the raw material.Be more preferably, said sweet substance is a kind of in sucrose, fructose, honey, oligoisomaltose, soyabean oligosaccharides, the hydroxyl isomaltulose or several.
The oral donkey-hide gelatin series of products of aforementioned functional, preferred scheme is also to comprise black sesame powder and/or walnut meat powder 10-30 part in the raw material.
The present invention also provides the preparation method of the oral donkey-hide gelatin series of products of aforementioned functional, is donkey-hide gelatin is placed the dissolving of functional mass extract evenly; The degassing;-15 ℃----80 ℃ are freezing 224 hours; Vacuum freeze drying is cut, is packed and gets.Preferably, cryogenic temperature is-30 ℃----60 ℃, cooling time is 12-20 hour.More preferably, cryogenic temperature is-40 ℃----50 ℃, cooling time is 15-18 hour.
The preparation method of above-mentioned oral donkey-hide gelatin series of products is simple, unique flavor, taking convenience, is easy to carry.It has tonifying Qi and blood and stomach is calmed the nerves, strengthened muscle power, improves effects such as sleeping, increase appetite, raising body health level.Especially travel on official business and carry taking convenience, promptly change, do not need water, be easy to quantitatively take for a long time to mouth.
The present invention adopt the traditional Chinese medical science traditional " monarch, minister, help, make the compatibility of drugs principle "; In conjunction with the modern Chinese medicine research theory, will have collaborative each other Chinese medicine reasonable compatibility, extraction mass efficient element and vegetable protein, colloid are processed from various plants herbal medicine material; Wherein donkey-hide gelatin is a monarch drug in a prescription; Can carry out good facilitation to hemopoietic system, hematopoiesis materials such as rich in amino acid, calcium, iron, zinc are provided simultaneously, promote erythrocytic generation.Medicine-food two-purpose of the present invention, gentle safety, applied range.
In addition, excellent results of the present invention also is embodied in:
1, because has collaborative each other Chinese medicine reasonable compatibility; Auxilliary mutually the use carried out good facilitation to hemopoietic system, and hematopoiesis materials such as rich in amino acid, calcium, iron, zinc are provided simultaneously; Promote erythrocytic generation, finally reach the effect of regulating blood pressure, enriching blood.
2, can recover and improve the normal physiological function of each organs such as kidney, the heart, brain, spleen, enhancing human immune, health status is stable.
3, this product is easy to packing, has kept the advantage of donkey-hide gelatin, both conveniently takes, and has kept the useful effect of Chinese medicine again, takes the back active principle and discharges rapidly, digests and assimilates fully instant effect, definite effect.
The specific embodiment
Specify technical scheme of the present invention below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The medicine-food two-purpose material that the used functional mass of the present invention relates to and the main pharmacology of Chinese medicine material are following: donkey-hide gelatin: the property of medicine is sweet, and is flat.Return lung, liver, kidney channel.But medicine-food two-purpose, " donkey-hide gelatin, herbal classic is top grade, claims " obeying the beneficial gas of making light of one's life by commiting suicide for a long time " for the record of Li Shizhen (1518-1593 A.D.) Compendium of Material Medica.Main effect is the enriching yin of enriching blood, and moisturizes hemostasis.It is sallow to can be used for the general crowd and the deficiency of blood, dizzy palpitaition, and the flesh impotence is unable, dysphoria and insomnia, endogenous deficient wind, xeropulmonary cough, the labor spitting of blood of coughing, haematemesis hematuria, the diseases such as uterine bleeding, vaginal bleeding during pregnancy of having blood in stool.Poria cocos: the property of medicine is sweet, light, and is flat.The thoughts of returning home, spleen, kidney channel.Main effect is eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative.Can be used for difficult urination, oedema turgor, phlegm and retained fluid cough contrary, vomiting, insufficiency of the spleen food less, have loose bowels, disease such as palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea.American Ginseng: sweet, the little hardship of the property of medicine, cold.The thoughts of returning home, lung, kidney channel.Main effect is boosting qi and nourishing yin, clearing heat and promoting fluid.Be used for that the deficiency of vital energy cloudy is lost, interior heat, cough breathe heavily phlegm blood, abnormal heat tired tired, quench one's thirst, dryness of the mouth and throat.The modern pharmacological research result shows that American Ginseng has antifatigue, anti-oxidant, the anti-effect that stress, suppress platelet aggregation, reduces blood clotting property; The diabetic is regulated in addition the effect of blood sugar; Saponin in the American Ginseng can effectively strengthen nervous centralis, reach with all worries set aside with fixed attention, eliminate effects such as fatigue, enhance memory power, applicable to insomnia, agitation, be losing one's memory and symptom such as senile dementia; Can protect cardiovascular system, improve immunity etc.Chinese yam: the property of medicine is sweet, and is flat.Return spleen, lung, kidney channel.But medicine-food two-purpose is according to Shennong's Herbal record Chinese yam " bowl spares, beneficial strength, longue meat ".According to Compendium of Material Medica record Chinese yam " kidney-nourishing gas, strengthening the spleen and stomach ".Main effect is the tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, and the puckery essence of kidney tonifying reduces blood sugar, promotes longevity.Can be used for general crowd and syndrome of spleen deficiency, deficiency syndrome of the lung card, nephrasthenia syndrome, the syndrome of deficiency of both qi and yin etc. of quenching one's thirst.Arillus longan: nature and flavor are sweet, temperature.The thoughts of returning home, the spleen channel.But medicine-food two-purpose is according to " daily book on Chinese herbal medicine " record arillus longan " peaceful heart of intelligence development." " must join book on Chinese herbal medicine " think: " beneficial taste are preserved painstaking effort to longan, and moisturizing viscera is controlled palpitation." " Quanzhou book on Chinese herbal medicine " think: longan " establishing-Yang benefit gas, tonifying spleen and stomach." main effect is tonifying heart and spleen, nourishing blood and tranquilization, invigorating the spleen to arrest diarrhea, inducing diuresis to reduce edema etc.Can be used for sallow, the illness such as body void after being ill of general crowd and insufficiency of vital energy and blood, palpitation and severe palpitation, forgetful insomnia, neurasthenia, the deficiency of blood.Matrimony vine: the property of medicine is sweet, flat, returns liver, kidney channel; But medicine-food two-purpose, " nourishing the liver makes eye bright for matrimony vine, kidney-tonifying sperm-generating, and hard smart bone goes fatigue, is prone to color, bleaches, and makes eye bright and calms the nerves, and makes us long-lived according to the Compendium of Material Medica record." main effect is nourishing liver and kidney, nourishes the liver to improve visual acuity, moistening lung is promoted the production of body fluid, beneficial complexion, and longue meat, hard muscles and bones, clothes have and promote longevity the effect that delays senility for a long time.Can be used for general crowd and caused by liver and kidney deficiency, soreness and weakness of waist and knees, impotence and seminal emission, have a dizzy spell, blurring of vision, cough due to consumptive disease, card such as quench one's thirst.Dried orange peel: the property of medicine is hot, bitter, temperature.Return spleen, lung channel.But medicine-food two-purpose, main effect is a regulating qi-flowing for strengthening spleen, in the accent, eliminating dampness is reduced phlegm.The abdominal fullness and distention of the crowd and the taste stagnation of the circulation of vital energy or pain, indigestion as can be used for.Abdominal distension uncomfortable in chest in the wet turbid resistance, vomiting, hiccup card, indigestion and loss of appetite loose stool, phlegm disease such as wet.Citron: the property of medicine is hot, bitter, sour, temperature.Return liver, lung, the spleen channel.Main effect is full vexed for the chest abdomen; The distending pain in hypochondrium.Buddha's hand: the property of medicine is hot, bitter, sour, temperature.Return liver, spleen, lung channel.Main effect is a liver-smoothing, qi-regulating, and stomach and alleviating pain.Be used for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, the gastral cavilty ruffian is full, the few vomiting of food.Fructus amomi: nature and flavor: flavor is hot, and is warm in nature.Return the spleen channel, stomach warp, kidney channel.Main effect is the dampness elimination appetizing, and warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy.Peppermint: nature and flavor: suffering, cold.Return lung, Liver Channel.Main effect is a dispelling wind-heat, refresh oneself, promoting eruption.Can be used for anemopyretic cold, wind-warm syndrome is from the beginning of, headache, hot eyes, larynx numbness, aphtha, rubella, measles, the chest side of body vexed disease of waiting of expanding.Hawthorn: property of medicine acid, sweet, tepor.Return spleen, stomach, Liver Channel; But medicine-food two-purpose, " change diet, the meat that disappears is long-pending, abdominal mass, the full acid regurgitation of phlegm and retained fluid ruffian, stagnant blood distending pain according to Compendium of Material Medica record hawthorn." main effect is promoting digestion and removing indigestion, the promoting the circulation of qi stasis of blood of loosing.Can be used for cards such as general crowd and eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia.Date: the property of medicine is sweet, temperature.Return spleen, stomach warp.But medicine-food two-purpose " is supported spleen " according to Shennong's Herbal record date in the peace.According to " Mingyi Bielu " record date " tonifying middle-Jiao and Qi, brute force are removed unhappy ".Main effect is tonifying middle-Jiao and Qi, nourishing blood and tranquilization.Can be used for general crowd and insufficiency of the spleen, cards such as consumptive disease is unhappy, insomnia.
The oral donkey-hide gelatin product of 1 one kinds of functions of embodiment adopts the preparation of functional mass aqueous extract dissolving donkey-hide gelatin, and step is following: Poria cocos 20g is got in (1), American Ginseng 10g; Chinese yam 20g, arillus longan 6g, matrimony vine 10g, dried orange peel 6g; Hawthorn 6g, date 10g adds water 1800g; Decocted 35 minutes, and filtered, it is subsequent use that filtrating is concentrated into 1000g.(2) get that donkey-hide gelatin 40g pulverizes, 15g honey is dissolved in (1) gained filtrating, stir.(3) (2) gained material is put the degassing in the mould (stainless steel disc or porcelain dish all can); (4)-50 ℃ freezing 15 hours; (5) vacuum freeze drying, cutting, packing gets final product.
The oral donkey-hide gelatin product of 2 one kinds of functions of embodiment adopts the preparation of functional mass aqueous extract dissolving donkey-hide gelatin, and step is following: Poria cocos 15g is got in (1), citron 10g; Buddha's hand 10g, Chinese yam 15g, fructus amomi 6g, peppermint 6g; Matrimony vine 8g, dried orange peel 4g, hawthorn 4g, date 8g; Add water 1500g, decocted 25 minutes, filter, it is subsequent use that filtrating is concentrated into 900g.(2) get donkey-hide gelatin 10g and pulverize, be dissolved in (1) gained filtrating, add honey 10g, stir.(3) (2) gained material is put outgased in the mould; (4)-80 ℃ freezing 2 hours; (5) vacuum freeze drying, cutting, packing gets final product.
The oral donkey-hide gelatin product of 3 one kinds of functions of embodiment adopts the preparation of functional mass aqueous extract dissolving donkey-hide gelatin, and step is following: Poria cocos 25g is got in (1), American Ginseng 15g; Chinese yam 25g, arillus longan 10g, matrimony vine 12g, dried orange peel 8g; Hawthorn 8g, date 15g adds water 2200g; Decocted 45 minutes, and filtered, it is subsequent use that filtrating is concentrated into 1200g.(2) get donkey-hide gelatin 50g and pulverize, be dissolved in (1) gained filtrating, add black sesame powder 30g, stir.(3) (2) gained material is put the degassing in the mould (stainless steel disc or porcelain dish all can); (4)-60 ℃ freezing 12 hours; (5) vacuum freeze drying, cutting, packing gets final product.
The oral donkey-hide gelatin product of 4 one kinds of functions of embodiment adopts the preparation of functional mass aqueous extract dissolving donkey-hide gelatin, and step is following: Poria cocos 13g is got in (1), citron 8g; Buddha's hand 8g, Chinese yam 12g, fructus amomi 4g, peppermint 4g; Matrimony vine 6g. dried orange peel 2g, hawthorn 2g, date 6g adds water 1800g; Decocted 25 minutes, and filtered, it is subsequent use that filtrating is concentrated into 1000g.(2) get donkey-hide gelatin 12g and pulverize, be dissolved in (1) gained filtrating, stir.(3) (2) gained material is put outgased in the mould; (4)-50 ℃ freezing 15 hours; (5) vacuum freeze drying, cutting, packing gets final product.
The oral donkey-hide gelatin product of 5 one kinds of functions of embodiment adopts the preparation of functional mass aqueous extract dissolving donkey-hide gelatin, and step is following: Poria cocos 17g is got in (1), citron 12g; Buddha's hand 12g, Chinese yam 17g, fructus amomi 8g, peppermint 8g; Matrimony vine 12g, dried orange peel 6g, hawthorn 6g, date 10g; Add water 2200g, decocted 35 minutes, filter, it is subsequent use that filtrating is concentrated into 1200g.(2) get donkey-hide gelatin 50g and pulverize, be dissolved in (1) gained filtrating, add soybean compound sugar 10g, stir.(3) (2) gained material is put outgased in the mould; (4)-60 ℃ freezing 12 hours; (5) vacuum freeze drying, cutting, packing gets final product.
Use product of the present invention can directly contain clothes, promptly change to mouth, taking convenience is convenient to take according to quantity for a long time.
Test Example 1
The embodiment of the invention 1 products obtained therefrom is treated the clinical testing that 90 examples belong to deficiency of qi and blood sub-health state patient, wherein women 58 examples, male 32 examples, oldest 52 years old, minimal ages 24 years old, 37.18 years old mean age in August, 2006-2009 year December.Inclusion criteria: have with next or above symptom also to continue person more than month.Lassitude hypodynamia is had a dizzy spell, palpitation, and the work of not enduring hardships, insomnia and dreamful sleep, sallow complexion, from sweating, easy catching a cold, indigestion and loss of appetite abdominal distension, companion's tongue is light or light red, and tongue is thin white, weak pulse.Except the organic disease. 2 weeks before the test, patient to be observed continuously, record symptom and variation are divided into two groups at random, experimental group and control group, experimental group is taken embodiment 1 products obtained therefrom, and control group is taken other health products.Method for using is: take 3-2 every day, takes each 3-8g after meal or between two meal.Every day, consumption was 24-3g; With one month was a course of treatment.Curative effect situation criterion: cure: take course of treatment of these article, hemochrome >=12, female menstrual period and normal through amount, the malaise symptoms disappearance, muscle power obviously strengthens; Effectively: take course of treatment of these article, hemochrome content >=12, female menstrual period and improve through amount, malaise symptoms alleviates or part disappears, and muscle power strengthens; Invalid: as to take course of treatment of these article, malaise symptoms no change.The result is as shown in table 1.
Table 1: take embodiment 1 product deficiency of qi and blood sub-health state crowd treatment results
Result of treatment: cure 13 examples (35.6%), effective 27 examples (60%), invalid 2 examples (4.4%), total effective rate 95.6%.
Effect obviously is superior to control group.Self-induction symptom and muscle power spirit thereof change as shown in table 2 during taking.
Table 2: take embodiment 1 product deficiency of qi and blood sub-health state crowd process result of variations
The used prescription of present embodiment is with donkey-hide gelatin, American Ginseng, Poria cocos, Chinese yam, arillus longan benefiting qi and nourishing blood, antitoxic heart-soothing and sedative; With the matrimony vine filling liver kidney, go fatigue; Dried orange peel, hawthorn are regulated the flow of vital energy and help digestion; The date qi-restoratives, coordinating the drug actions of a prescription; All medicines mutually with, the merit of blood-enrich, antitoxic heart-soothing and sedative is arranged.Took 10 days, feeling more than 62% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 20 days, feeling more than 86% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 30 days, feeling more than 95% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen.
Test Example 2
The embodiment of the invention 2 products obtained therefroms are treated the clinical testing that 76 examples belong to caused by hepatic stagnation qi stagnation sub-health state patient, wherein women 52 examples, male 24 examples, oldest 50 years old, minimal ages 27 years old, 38.1 years old mean age in August, 2006-2009 year December.Inclusion criteria: have with next or above symptom also to continue person more than month.Gloomy, demoralized, of few words few joyous, the chest distress of mood, chest side of body string pain, abdominal distension and anorexia are kindly sighed, dreaming often and waking easily, irregular menstruation, and companion's pink tongue or dark red, tongue is thin white or thin yellow, and arteries and veins is profound.Except the organic disease. in 2 weeks before the test, patient is observed continuously record symptom and variation; Be divided into two groups at random, experimental group and control group, experimental group is taken embodiment 2 products obtained therefroms; Control group is taken other health products; Method for using is: take 3-2 every day, takes each 3-9g after meal or between two meal.Every day, consumption was 27-9g; With one month was a course of treatment.
Curative effect situation criterion: cure: take course of treatment of these article, hemochrome >=12, female menstrual period and normal through amount, malaise symptoms disappears, the muscle power enhancing, the state of mind is clearly better; Take a turn for the better: take course of treatment of these article, hemochrome content >=12, female menstrual period and improve through amount, malaise symptoms alleviates or part disappears, and muscle power strengthens, state of mind improvement; Invalid: as to take course of treatment of these article, malaise symptoms no change.The result is as shown in table 3.
Table 3: take embodiment 2 product stagnation of QI due to depression of the liver sub-health state crowd treatment results
Result of treatment: cure 14 examples (36.84%), effective 23 examples (60.53%), invalid 1 example (2.63%), total effective rate 97.37%.Effect obviously is superior to control group.
Self-induction symptom and muscle power spirit thereof change as shown in table 4 during taking.
Table 4: take embodiment 2 product stagnation of QI due to depression of the liver sub-health state crowd process result of variations
The used prescription of present embodiment, with donkey-hide gelatin, matrimony vine nourishing blood and liver, citron, Buddha's hand, peppermint, fructus amomi dispersing stagnated hepatoqi are separated strongly fragrant, Chinese yam, Poria cocos, dried orange peel invigorating the spleen to dry, the hawthorn long-pending appetizing that disappears, date with in, all medicines share, can soothing liver-qi stagnation, regulate the flow of vital energy and in.Took 10 days, feeling more than 60% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 20 days, feeling more than 81% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Took 30 days, feeling more than 97% takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen.