CN101991649A - Medicament for treating allergic rhinitis - Google Patents
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- CN101991649A CN101991649A CN2009100180022A CN200910018002A CN101991649A CN 101991649 A CN101991649 A CN 101991649A CN 2009100180022 A CN2009100180022 A CN 2009100180022A CN 200910018002 A CN200910018002 A CN 200910018002A CN 101991649 A CN101991649 A CN 101991649A
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Abstract
The invention provides a medicament for treating allergic rhinitis, belonging to a medicament using traditional Chinese medicines as effective ingredients. The medicament for treating allergic rhinitis is prepared from the raw materials of milkvetch roots, small centipeda herbs, asarum, violet magnolia, cocklebur fruits, angelica roots, borneol, sesame oil and liquid paraffin. The medicament has good treatment effect, is convenient for use, overcomes the defects of long treatment course, great pain, high expense, more complications, easy relapse and the like of Western medicine treatment, and also overcomes the defects of slow effect taking, inconvenient use and the like of traditional Chinese pills, oral decoctions, patches and the like.
Description
Technical field
The medicine of a kind of treatment of allergic rhinitis of the present invention, especially a kind of with the medicine of Chinese medicine as effective ingredient.
Background technology
Allergic rhinitis claims allergic rhinitis again, is called for short allergic rhinitis, is the nasal mucosa inflammation that the allergy reason causes.Allergic rhinitis belongs to the traditional Chinese medical science " allergic rhinitis " category, is cardinal symptom with nasal obstruction, sneeze, rhinocnesmus, snivel etc.Present western medical treatment mainly contains specificity and non-specific two classes, exists patient's course of disease long, and painful big, cost is high, defectives such as easy recurrence.Chinese traditional treatment has pill, decoction oral, patch etc., mainly is symptomatic treatment, and relief of symptoms can not effect a radical cure, and it is slow not only to take effect, and uses inconvenient.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of medicine of treatment of allergic rhinitis, to improve the convenience of therapeutic effect and use.
The present invention realizes like this, a kind of medicine of treatment of allergic rhinitis, described medicine is by making as the Oleum sesami of adjuvant, liquid paraffin and as the raw materials of effective components medicine, Oleum sesami, liquid paraffin and be as the weight proportion of raw materials of effective components medicine:
The Radix Astragali 15～25 weight portions
Herba Centipedae 25～35 weight portions
Herba Asari 2～4 weight portions
Flos Magnoliae 4～8 weight portions
Fructus Xanthii 4～8 weight portions
The Radix Angelicae Dahuricae 8～12 weight portions
Borneolum Syntheticum 0.5～1.5 weight portion
Oleum sesami 450～550 weight portions
Liquid paraffin 25～35 weight portions.
The medicine of this treatment of allergic rhinitis, therapeutic effect is good, and is easy to use, and it is long the course of treatment to have overcome western medical treatment, painful big, cost is high, and complication is many, defectives such as easy recurrence, overcome traditional Chinese medical science pill, decoction oral, patch etc., it is slow to take effect, and uses defectives such as inconvenience.
The specific embodiment
Further specify the present invention below.
The traditional Chinese medical science thinks that allergic rhinitis is because of insufficiency of lung-QI, instability of surface, and the wind and cold invasion and attack, body fluid stops gathering, and causes due to the stuffy nose.
In the present invention's the medicine, Radix Astragali benefiting QI for strengthening the superficies, the tonifying the lung spleen invigorating is a monarch drug; Herba Asari Radix Angelicae Dahuricae warming lung for dispelling cold is a ministerial drug; Herba Centipedae, Flos Magnoliae, Fructus Xanthii, Borneolum Syntheticum, clear the nasal passage are adjuvant drug.
Modern pharmacology studies show that, the Radix Astragali mainly contains the tired analog derivative of triterpenoid saponin, flavone compound, polysaccharide, chlorine-containing compound, vitamin, other Organic substance and various trace elements, body immune system had extensive influence, based on immunostimulant, immunomodulating, the enhancing body nonspecific resistance has the positive therapeutic effect to viral, infectious disease and inflammation in respiratory system.Herba Asari mainly contains methyleugenol, volatilization wet goods composition, has antihistaminic and antiallergic action, immunosuppressant, antibiotic and lax tracheospasm effect.The Radix Angelicae Dahuricae mainly contains volatile oil, Ingredients Such As Coumarin, has antipyretic-antalgic, antiinflammatory, antipathogen effect.Flos Magnoliae mainly contains compositions such as volatile oil, Camphora, Borneolum Syntheticum, eugenol, isoeugenol, has antiallergic, antiinflammatory, analgesia, local convergence, anti-dopamine effect.Herba Centipedae contains pseudoguaianolides and Flavonoid substances, has antiallergic, antimutagenic, eliminating phlegm and stopping cough and antiasthmatic effect.Fructus Xanthii contains Fructus Xanthii methanol, oils and fats, resin and volatile oil, has antiinflammatory, analgesia, antibiotic, has respiratory tract motion reinforcement and waits effect.Borneolum Syntheticum contains Borneolum Syntheticum, isoborneol, has antiinflammatory, sterilization and sedation.Oleum sesami, liquid paraffin are blender, and be easy to use.
Can think that thus the mechanism of action of the present invention's Drug therapy allergic rhinitis is with to regulate immunity of organism, enhancing body nonspecific resistance, anti-inflammation, convergence astringent or styptic treatment for spontaneous sweating relevant.
Fructus Xanthii claims grey son again.
A kind of preparation method of the present invention's medicine is, take by weighing by proportioning and to get as raw materials of effective components medicine and Oleum sesami, liquid paraffin, the Radix Astragali, Herba Centipedae, Herba Asari, Flos Magnoliae, grey son, the Radix Angelicae Dahuricae are put into Oleum sesami soaked 24～48 hours, wherein, Flos Magnoliae will bind up with gauze, heat then, it is pulled out when the aforementioned base materials medicine is yellow black, put into Borneolum Syntheticum, liquid paraffin again, mixing, cold filtration, packing, sterilization again makes the drop of this medicine.
The using method of the present invention's medicine is, the patient faces upward head, makes the nostril up, at the uniform velocity splashes into 3～5 of the drops of the present invention's medicine, and every day 4～6 times, 1 week was a course of treatment, total 3 weeks of the course of treatment.
Be the clinical effectiveness of the Drug therapy allergic rhinitis that shows the present invention, use present common drug furacilin-ephedrine solution collunariums and 160 examples to use the cases of the present invention's Drug therapy allergic rhinitis, contrast with 168 examples.
Use the patient of drop of the present invention's medicine to be test group, administrated method is with above-mentioned.Using the matched group that is of furacilin-ephedrine solution collunarium, use the furacilin-ephedrine solution collunarium, also is to splash in patient's nose, and each 3～5, every day 4～6 times, 1 week was a course of treatment, total 3 weeks of the course of treatment.
The diagnostic criteria of allergic rhinitis: with the related content in " eye, the otolaryngologic disease diagnostic criteria " of Shu Huai chief editor, the publication in August calendar year 2001 of Beijing science tech publishing house is standard.Concrete standard is: 1, perennial onset has clinical manifestations such as sneeze (each continuous more than 5), snivel and nasal mucosa swelling.Morbidity month number surpasses 6 months in 1 year, and disease time was above 0.5 hour on 1st.2, the course of disease is at least more than half a year.3, comprehensive grading is more than 6 minutes.The score standard: 1. clear and definite inhalation (inhalatio) sensitinogen clue is arranged, a guy or (with) family's allergies,, there are typical symptoms and sign stage of attack, each remembers 1 fen, totally 3 minutes.2. allergen tuerculoderma positive reaction has a kind of be (++) or more than (++) at least, and specificity antibody IgE detects the positive or the allergen provocative test positive, and meets with tuerculoderma and medical history, each gets totally 4 minutes 2 fens.3. nasal smear eosinophilic granulocyte and/or mastocyte (eosinophilic granulocyte) are positive got 1 fen.Score 6～8 minutes is diagnosable to be long-term allergic rhinitis.
Curative effect determinate standard; Cure: clinical symptom disappearance, other relevant inspection reaches normal substantially.Produce effects: clinical symptoms disappears substantially, or by the serious symptom disease that lightens, other relevant inspection is clearly better.Effectively: clinical symptom relief, disease in becoming as serious symptom, the middle disease disease that lightens, other relevant inspection is taken a turn for the better.Invalid: the clinical symptoms no change, other relevant inspection does not have improvement.
Case choice criteria and eliminating case standard: 1, case choice criteria: select to meet allergic rhinitis diagnostic criteria person and be the object of observation.2, get rid of the case standard: 1. differential diagnosis in tcm is indeterminate, or the folder disease of too much holding concurrently is arranged.2. the age is below 15 years old, or more than 45 years old; Gestation or women breast-feeding their children; Medicine or furacilin-ephedrine solution collunarium allergy sufferers to the present invention.3. do not meet the standard of including in, do not take medicine in accordance with regulations, can't judge curative effect, or clinical data is not congruent affects the treatment or safety judgement person.3, the symptom grade scale be light, in, heavy.Gently: sneeze, one-time continuous is more than 5; Watery nasal discharge: blow one's nose every day more than 4 times, idol has nasal obstruction.In: sneeze, one-time continuous is more than 10; Watery nasal discharge: blow one's nose every day more than 5 times, nasal obstruction is between light and weight.Heavy: sneeze, one-time continuous is more than 15; Watery nasal discharge: blow one's nose more than 10 times nasal obstruction, almost whole day mouth breathing every day.
In two groups of cases, situations such as patient's age, the state of an illness, M-F are suitable, and comparability is arranged.
Observation index and method: 1, health giving quality is observed: patient symptom and sign observation, allergen skin test, nasal smear are observed.2, observational technique: observe preceding detailed medical history-taking of treatment and clinical symptoms, system's physical examination, check in per as the case may be 7 days once except that observing by These parameters, is write down clinical symptoms and sign at any time and is changed during the treatment.Observe and finish the every observation index of back check,, and carry out statistical procedures in strict accordance with criterion of therapeutical effect evaluation curative effect.
The clinical efficacy situation sees the following form:
Situation of change sees the following form before and after two groups of symptoms and the sign treatment:
Change before and after two groups of lab testing treatments and see the following form:
From above-mentioned each table as can be seen, the therapeutic effect of the present invention's medicine obviously is better than drop furacilin-ephedrine solution collunarium commonly used at present.In addition, paid a return visit after 6 months, test group is cured case does not have recurrence.
Embodiment 1
Take by weighing the Radix Astragali 15 weight portions, Herba Centipedae 35 weight portions, Herba Asari 2 weight portions, Flos Magnoliae 8 weight portions, Fructus Xanthii 4 weight portions, the Radix Angelicae Dahuricae 12 weight portions, Borneolum Syntheticum 0.5 weight portion, Oleum sesami 550 weight portions, liquid paraffin 25 weight portions.Preparation method is, the Radix Astragali, Herba Centipedae, Herba Asari, Flos Magnoliae, grey son, the Radix Angelicae Dahuricae are put into Oleum sesami to be soaked 48 hours, wherein, Flos Magnoliae will bind up with gauze, and heats then, it is pulled out when the aforementioned base materials medicine is yellow black, put into Borneolum Syntheticum, liquid paraffin again, mixing, cold filtration, packing, sterilization again makes the drop of this medicine.
Embodiment 2
Take by weighing the Radix Astragali 25 weight portions, Herba Centipedae 25 weight portions, Herba Asari 4 weight portions, Flos Magnoliae 4 weight portions, Fructus Xanthii 8 weight portions, the Radix Angelicae Dahuricae 8 weight portions, Borneolum Syntheticum 1.5 weight portions, Oleum sesami 450 weight portions, liquid paraffin 35 weight portions.Preparation method is, the Radix Astragali, Herba Centipedae, Herba Asari, Flos Magnoliae, grey son, the Radix Angelicae Dahuricae are put into Oleum sesami to be soaked 24 hours, wherein, Flos Magnoliae will bind up with gauze, and heats then, it is pulled out when the aforementioned base materials medicine is yellow black, put into Borneolum Syntheticum, liquid paraffin again, mixing, cold filtration, packing, sterilization again makes the drop of this medicine.
Embodiment 3
Take by weighing the Radix Astragali 20 weight portions, Herba Centipedae 30 weight portions, Herba Asari 3 weight portions, Flos Magnoliae 6 weight portions, Fructus Xanthii 6 weight portions, the Radix Angelicae Dahuricae 10 weight portions, Borneolum Syntheticum 1.0 weight portions, Oleum sesami 500 weight portions, liquid paraffin 30 weight portions.Preparation method is, the Radix Astragali, Herba Centipedae, Herba Asari, Flos Magnoliae, grey son, the Radix Angelicae Dahuricae are put into Oleum sesami to be soaked 36 hours, wherein, Flos Magnoliae will bind up with gauze, and heats then, it is pulled out when the aforementioned base materials medicine is yellow black, put into Borneolum Syntheticum, liquid paraffin again, mixing, cold filtration, packing, sterilization again makes the drop of this medicine.
Claims (1)
1. the medicine of a treatment of allergic rhinitis is characterized in that, described medicine is by making as the Oleum sesami of adjuvant, liquid paraffin and as the raw materials of effective components medicine, Oleum sesami, liquid paraffin and be as the weight proportion of raw materials of effective components medicine:
The Radix Astragali 15～25 weight portions
Herba Centipedae 25～35 weight portions
Herba Asari 2～4 weight portions
Flos Magnoliae 4～8 weight portions
Fructus Xanthii 4～8 weight portions
The Radix Angelicae Dahuricae 8～12 weight portions
Borneolum Syntheticum 0.5～1.5 weight portion
Oleum sesami 450～550 weight portions
Liquid paraffin 25～35 weight portions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100180022A CN101991649A (en) | 2009-08-11 | 2009-08-11 | Medicament for treating allergic rhinitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100180022A CN101991649A (en) | 2009-08-11 | 2009-08-11 | Medicament for treating allergic rhinitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101991649A true CN101991649A (en) | 2011-03-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100180022A Pending CN101991649A (en) | 2009-08-11 | 2009-08-11 | Medicament for treating allergic rhinitis |
Country Status (1)
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102648934A (en) * | 2011-02-24 | 2012-08-29 | 邴守兰 | Traditional Chinese medicine composition for treating chronic simple rhinitis and preparation method thereof |
| CN102657709A (en) * | 2012-03-19 | 2012-09-12 | 马广明 | A traditional Chinese medicine for treating rhinitis |
| CN102688314A (en) * | 2012-03-27 | 2012-09-26 | 荆金锁 | Traditional Chinese medicine for treating rhinitis |
| CN103182037A (en) * | 2012-01-01 | 2013-07-03 | 李书彬 | Traditional Chinese medicine for treating rhinitis |
| CN104173546A (en) * | 2014-09-03 | 2014-12-03 | 王继礼 | Traditional Chinese medicine liquid for treating rhinitis |
| CN104523826A (en) * | 2015-01-23 | 2015-04-22 | 李海红 | Medicine for treating nasosinusitis |
| CN105055518A (en) * | 2015-08-28 | 2015-11-18 | 柳州市妇幼保健院 | Traditional Chinese medicine fumigant for treating child rhinitis |
| WO2017219846A1 (en) * | 2016-06-20 | 2017-12-28 | 东莞市乐堂医疗投资有限公司 | Externally-used traditional chinese medicine preparation for treating rhinitis, and preparation method therefor |
| CN106540051B (en) * | 2016-11-30 | 2018-07-24 | 谭智成 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
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| CN109568380A (en) * | 2019-01-09 | 2019-04-05 | 义乌凌川科技有限公司 | It is a kind of to treat rhinitis Chinese medicine and preparation method thereof |
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| CN113940955A (en) * | 2020-07-16 | 2022-01-18 | 陕西家有爸妈九和药业有限公司 | Traditional Chinese medicine sachet for treating allergic rhinitis and preparation method thereof |
| CN117771296A (en) * | 2023-09-18 | 2024-03-29 | 旌德县万方日用品有限公司 | Composition for preventing allergic rhinitis |
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| CN102648934A (en) * | 2011-02-24 | 2012-08-29 | 邴守兰 | Traditional Chinese medicine composition for treating chronic simple rhinitis and preparation method thereof |
| CN103182037A (en) * | 2012-01-01 | 2013-07-03 | 李书彬 | Traditional Chinese medicine for treating rhinitis |
| CN102657709A (en) * | 2012-03-19 | 2012-09-12 | 马广明 | A traditional Chinese medicine for treating rhinitis |
| CN102688314A (en) * | 2012-03-27 | 2012-09-26 | 荆金锁 | Traditional Chinese medicine for treating rhinitis |
| CN104173546A (en) * | 2014-09-03 | 2014-12-03 | 王继礼 | Traditional Chinese medicine liquid for treating rhinitis |
| CN104523826A (en) * | 2015-01-23 | 2015-04-22 | 李海红 | Medicine for treating nasosinusitis |
| CN105055518A (en) * | 2015-08-28 | 2015-11-18 | 柳州市妇幼保健院 | Traditional Chinese medicine fumigant for treating child rhinitis |
| WO2017219846A1 (en) * | 2016-06-20 | 2017-12-28 | 东莞市乐堂医疗投资有限公司 | Externally-used traditional chinese medicine preparation for treating rhinitis, and preparation method therefor |
| CN106540051B (en) * | 2016-11-30 | 2018-07-24 | 谭智成 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
| CN108853288A (en) * | 2017-05-11 | 2018-11-23 | 季顺进 | A kind of nose is logical to be dissipated and preparation method thereof |
| CN108619242A (en) * | 2018-08-17 | 2018-10-09 | 深圳神思汉方生物科技有限公司 | A kind of rhinitis ointment |
| CN109010490A (en) * | 2018-10-24 | 2018-12-18 | 邓丰锡 | A kind of Chinese medicine for treating allergic rhinitis |
| CN109010490B (en) * | 2018-10-24 | 2022-08-16 | 邓丰锡 | Traditional Chinese medicine for treating allergic rhinitis |
| CN109568380A (en) * | 2019-01-09 | 2019-04-05 | 义乌凌川科技有限公司 | It is a kind of to treat rhinitis Chinese medicine and preparation method thereof |
| CN111494520A (en) * | 2020-06-18 | 2020-08-07 | 白振雪 | Medicine for treating rhinitis and preparation method and application thereof |
| CN113940955A (en) * | 2020-07-16 | 2022-01-18 | 陕西家有爸妈九和药业有限公司 | Traditional Chinese medicine sachet for treating allergic rhinitis and preparation method thereof |
| CN117771296A (en) * | 2023-09-18 | 2024-03-29 | 旌德县万方日用品有限公司 | Composition for preventing allergic rhinitis |
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