CN101804958B - Sterile negative pressure isolation facility of capping machine - Google Patents
Sterile negative pressure isolation facility of capping machine Download PDFInfo
- Publication number
- CN101804958B CN101804958B CN2010101734837A CN201010173483A CN101804958B CN 101804958 B CN101804958 B CN 101804958B CN 2010101734837 A CN2010101734837 A CN 2010101734837A CN 201010173483 A CN201010173483 A CN 201010173483A CN 101804958 B CN101804958 B CN 101804958B
- Authority
- CN
- China
- Prior art keywords
- cabin
- cover
- rotating disk
- roll
- bottle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002955 isolation Methods 0.000 title claims abstract description 18
- 238000005192 partition Methods 0.000 claims abstract description 34
- 238000005096 rolling process Methods 0.000 claims description 79
- 238000009423 ventilation Methods 0.000 claims description 51
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 17
- 229910052782 aluminium Inorganic materials 0.000 claims description 17
- 239000004411 aluminium Substances 0.000 claims description 17
- 230000003139 buffering effect Effects 0.000 claims description 12
- 238000005516 engineering process Methods 0.000 claims description 11
- 239000002245 particle Substances 0.000 claims description 9
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 8
- 239000011521 glass Substances 0.000 claims description 5
- 239000013618 particulate matter Substances 0.000 claims description 3
- 238000009428 plumbing Methods 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000003749 cleanliness Effects 0.000 abstract description 9
- 239000000428 dust Substances 0.000 abstract 3
- 230000005540 biological transmission Effects 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 108010066114 cabin-2 Proteins 0.000 description 15
- 239000003814 drug Substances 0.000 description 7
- 238000004140 cleaning Methods 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000011109 contamination Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Images
Landscapes
- Accommodation For Nursing Or Treatment Tables (AREA)
Abstract
The invention discloses a sterile negative pressure isolation facility of a capping machine, which comprises a filling room (1), a capping cabin (2), a bottle discharge room (3), an A operation cabin (4), a B operation cabin (5), a transmission cabin (6) and the capping machine (7). The facility separates all functional parts and manual operation areas of the capping machine with transparent partition walls, to form mutually isolated working areas and functional cabin facilities; a negative pressure exhaust facility is arranged below the capping machine, for removing the dust produced in capping in real time; all the areas and the cabins are isolated and communicated by sterile air pressure difference, i.e. the technical scheme of sterile negative pressure isolation, communication and operation overcomes the problems and the defects of dust pollution and difficulty of the cleanliness of the capping environment in meeting standards; and the provided sterile negative pressure isolation facility of the capping machine ensures that the capping environment of the capping machine achieves the purposes that the dust pollution is eliminated and the cleanliness meets the standards through sterile negative pressure isolation.
Description
Technical field
The present invention relates to the isolation facility of the aseptic operation of pharmaceutical manufacturing equipment, specifically be meant the isolation method that adopts sterile negative pressure, make Cover-rolling machine be in the sterile negative pressure isolation facility of a kind of Cover-rolling machine that seals operation in the gnotobasis.
Background technology
Cover-rolling machine is in the production of medicine or food, under clean environment the container of having jumped a queue is carried out the equipment that aluminium lid or aluminium-plastic cap seal.After medicine filling and stopper-adding or freeze-drying tamponade, need be delivered to Cover-rolling machine and roll the cap seal mouth.1998 editions " minimum requirements " of rolling lid for non-final sterilized prod is 100,000 grades (D levels); Many Cover-rolling machine is placed under 100,000 grades of 100 grades of laminar flow hood of rolling between lid of general producer moved, and it is quite serious to rolling between lid pollution to roll a large amount of aluminium bits, chips of glass and other dirt bits that produce when cover, makes the cleanliness dynamic monitoring of rolling between lid be difficult to up to standard.Behind the medicine filling and stopper-adding and before rolling lid, plug is actually " non-complete sealing state " at the state of bottleneck, there is the situation that plug is loosening even jumping is filled in, roll the germ-free condition of the dirt bits pollution entail dangers to medicine between lid, and this single bottle of contamination phenomenon is difficult to detect.China medicine prison department has clearly stipulated rolling lid and must carrying out of non-final sterilized prod in " the A level under the B level background " environment when revision version GMP in 2010; Yet prior art is because aluminium bits, chips of glass and other dirt bits to rolling the pollution between lid, can't satisfy the requirement of new edition GMP.Therefore, the prior art cleanliness that exists dirt bits to pollute, roll the bezel ring, border is difficult to problems and shortcomings up to standard.
Summary of the invention
At the problems and shortcomings that above-mentioned prior art exists, the present invention adopts transparent partition wall that each the functional part and the manual operation region separation of Cover-rolling machine are come, and constitutes the work area and the functional cabin facility of isolating mutually; The ventilation and negative pressure ventilation facility is set under Cover-rolling machine, removes in real time and roll the dirt bits that lid produces; Between each zone, cabin, taking aseptic draught head to isolate is communicated with, be that sterile negative pressure is isolated the technical scheme that is communicated with operation, a kind of sterile negative pressure isolation facility of Cover-rolling machine is provided, be intended to isolate, guarantee that the bezel ring, border of rolling of Cover-rolling machine reaches the pollution of elimination dirt bits, cleanliness purpose up to standard by sterile negative pressure.
The object of the present invention is achieved like this: a kind of sterile negative pressure isolation facility of Cover-rolling machine, comprise bottling department, roll cover between cabin, bottle outlet, first operational window, second operational window, transferring cabin, Cover-rolling machine, wherein: described bottling department, roll cover between cabin, bottle outlet, first operational window, second operational window, transferring cabin be for being isolated each job shop and the cabin that surrounds by transparent partition wall; Press the left-right and front-back orientation and describe, roll that to cover the cabin be to roll the cabin of covering operation; Rolling the next door, the left side of covering the cabin is the bottling department that is provided with the can operation of filling apparatus, and rolls the left side partition wall that covers the cabin and be provided with the bottleneck that advances that communicates with bottling department, and advances bottleneck and be provided with valve; Roll the next door, the right of covering the cabin for handling between the bottle outlet that seals the back finished product, and roll the right partition wall that covers the cabin be provided with bottle outlet between communicate go out bottleneck, and go out bottleneck and be provided with valve; Roll the first operational window that the next door, front of covering the cabin is a manual work, and roll the front partition wall that covers the cabin and be provided with the gloves handle hole of isolating with the first operational window; Roll the second operational window that the next door, back of covering the cabin is a manual work, and roll the back partition wall that covers the cabin and be provided with the gloves handle hole of isolating with the second operational window; Be positioned at and roll the place, left front corner of covering the cabin and be provided with by the clear glass partition wall and isolate the transferring cabin that surrounds, and transferring cabin is provided with the Men Yujia operational window and communicates; Be positioned at partition wall place, the left side between bottle outlet be provided with one with roll cover the cabin, the first operational window is adjacent and the technology passageway that be used for aseptic isolation roughing-in purposes adjacent with the front partition wall of second operational window; Be laid with in the technology passageway and Cover-rolling machine bottom bonded assembly, by the ventilation and negative pressure ventilation pipe of negative pressure induced wind machine driving.
Each job shop all is provided with baroceptor separately with the cabin and is connected with described control housing;
Be positioned at the right-hand of second operational window front partition wall, be provided with plumbing connection of the same name separately in compressed-air cleaner, ozone generator and the technology passageway; Be positioned at the left of second operational window front partition wall, be provided with, each job shop and cabin air pressure are carried out control housing automatic follow-up control, able to programme, preset control parameters by the air door of control ventilation and negative pressure ventilation pipe in each job shop and cabin; The roof portion in each job shop and cabin is equipped with the ventilation inlet of the high efficiency particle air filter that is called as HEPA; The air outlet place that effluxes of ventilation and negative pressure ventilation pipe is provided with solid particulate matter separated and collected device and the high efficiency particle air filter of being convenient to change;
Described Cover-rolling machine is for carrying out the equipment that aluminium lid or aluminium-plastic cap roll the cap seal mouth automatically to the container of having jumped a queue; Cover-rolling machine is by sending a bottle buffering rotating disk, advance a bottle rotating disk, rolling and cover rotating disk, bottle outlet rotating disk, bottle outlet dish, aluminium lid hopper and constitute; Cover-rolling machine rolls the bottom of covering rotating disk and is provided with the table top slope, and the below on table top slope is provided with pipeline and links to each other with described ventilation and negative pressure ventilation pipe;
Cover-rolling machine and each job shop and mutual alignment, cabin and annexation:
Bottle buffering rotating disk that send of Cover-rolling machine is located in the bottling department, is positioned at into bottle mouth position; Cover-rolling machine advance a bottle rotating disk, roll cover rotating disk, the bottle outlet rotating disk is located to roll and covers in the cabin; Wherein, advance bottle rotating disk and be positioned at and roll the left side of covering rotating disk, the bottle outlet rotating disk is positioned at and rolls the right of covering rotating disk, advances bottle rotating disk and links to each other with bottle buffering rotating disk that send that is positioned at bottling department by advancing bottleneck, and the bottle outlet rotating disk links to each other with the bottle outlet dish that is positioned between bottle outlet by going out bottleneck; The bottle outlet dish of Cover-rolling machine is positioned at bottle mouth position in being located between bottle outlet; The aluminium lid hopper of Cover-rolling machine is located in the transferring cabin;
The air pressure setting in each job shop and cabin:
During work, by control housing control, each job shop with the control of cabin baric gradient by height to hanging down is, bottling department, rolls and covers between cabin, bottle outlet; That is, roll that to cover the relative bottling department in cabin be negative pressure, roll to cover to be malleation between the relative bottle outlet in cabin, air pressure is minimum between bottle outlet, and air-flow mobilely between cabin, bottle outlet is effluxed through the ventilation and negative pressure ventilation pipe to rolling cover by bottling department.
Principle of work
During work, aluminium lid sterilized by manually delivering to the transferring cabin aluminium lid hopper of packing into, medicine bottle in bottling department can tamponade, bottle buffering rotating disk that send by Cover-rolling machine enters to roll and covers the cabin from advancing bottleneck, send into to roll and cover rotating disk and roll the cap seal mouth through advancing a bottle rotating disk, leave to roll and cover the cabin and arrive bottle outlet dish between bottle outlet by going out bottleneck through the bottle outlet rotating disk again; Roll and cover rotating disk and roll the dirt bits that lid produces, cover below the rotating disk by being located to roll, the pipeline that links to each other with the table top slope effluxes by described ventilation and negative pressure ventilation pipe;
The negative pressure separation principle
Extraneous air enters each job shop and cabin by the ventilation inlet that roof portion is provided with high efficiency particle air filter; Roll the air that covers the cabin, major part discharges through the ventilation and negative pressure ventilation pipe, and few part is discharged between bottle outlet from going out bottleneck because of pressure reduction; Control housing by to each job shop and cabin advance exhaust air rate control, baric gradient is controlled to be to low by height, bottling department, roll and cover between cabin, bottle outlet; That is, roll that to cover the relative bottling department in cabin be negative pressure, roll to cover to be malleation between the relative bottle outlet in cabin, minimum between bottle outlet, make air-flow cover nonreturn flow between cabin, bottle outlet to rolling by bottling department; Thereby guarantee bottling department, roll the environment cleanliness that covers the cabin.
During work, can manually operate Cover-rolling machine by gloves handle hole and special tool, behind the end-of-job, close into bottleneck and the valve that goes out bottleneck, manually by the pressurized air of gloves handle hole after with compressed air filter degerming filtering bacterium to the Cover-rolling machine cleaning of blowing, dirt is considered to be worth doing and is effluxed by the ventilation and negative pressure ventilation pipe; After the cleaning, open ozone generator and carry out ozone sterilization.
Above-mentioned, the present invention adopts transparent partition wall that each the functional part and the manual operation region separation of Cover-rolling machine are come, and constitutes the work area and the functional cabin facility of isolating mutually; The ventilation and negative pressure ventilation facility is set under Cover-rolling machine, removes in real time and roll the dirt bits that lid produces; Between each zone, cabin, taking aseptic draught head to isolate is communicated with, be that sterile negative pressure is isolated the technical scheme that is communicated with operation, overcome the cleanliness that prior art exists the dirt bits to pollute, roll the bezel ring, border and be difficult to problems and shortcomings up to standard, the sterile negative pressure isolation facility of a kind of Cover-rolling machine that is provided, isolate by sterile negative pressure, guaranteed that the bezel ring, border of rolling of Cover-rolling machine reaches the pollution of elimination dirt bits, cleanliness purpose up to standard.
Description of drawings
Fig. 1 is the plane figure scheme drawing of the sterile negative pressure isolation facility of a kind of Cover-rolling machine of the present invention;
Fig. 2 is that scheme drawing cuts open in the office of looking up of Fig. 1.
Below in conjunction with the embodiment in the accompanying drawing the present invention is described in further detail, but should not be construed as any limitation of the invention.
Among the figure: bottling department 1, roll cover cabin 2, advance bottleneck 21, go out bottleneck 22, between ventilation and negative pressure ventilation pipe 23, bottle outlet 3, first operational window 4, second operational window 5, transferring cabin 6, compressed-air cleaner 01, ozone generator 02, control housing 03, technology passageway 04, transparent partition wall 05, gloves handle hole 06, high efficiency particle air filter 07, Cover-rolling machine 7, send a bottle buffering rotating disk 71, advance bottle rotating disk 72, roll and cover rotating disk 73, bottle outlet rotating disk 74, bottle outlet dish 75, aluminium lid hopper 76, table top slope 77.
The specific embodiment
Consult Fig. 1～Fig. 2, the sterile negative pressure isolation facility of a kind of Cover-rolling machine of the present invention, comprise bottling department 1, roll cover between cabin 2, bottle outlet 3, first operational window 4, second operational window 5, transferring cabin 6, Cover-rolling machine 7, wherein: described bottling department 1, roll cover between cabin 2, bottle outlet 3, first operational window 4, second operational window 5, transferring cabin 6 be for isolating each job shop and the cabin that surrounds by transparent partition wall 05; Press the left-right and front-back orientation and describe, roll and cover cabin 2 for rolling the cabin of covering operation; Rolling the next door, the left side of covering the cabin is the bottling department 1 that is provided with the can operation of filling apparatus, and roll the left side partition wall that covers the cabin be provided with communicate with bottling department 1 advance bottleneck 21, and advance bottleneck and be provided with valve; Roll the next door, the right of covering the cabin for handling between the bottle outlet that seals the back finished product 3, and roll the right partition wall that covers the cabin be provided with bottle outlet between 3 communicate go out bottleneck 22, and go out bottleneck and be provided with valve; Roll the first operational window 4 that the next door, front of covering the cabin is a manual work, and roll the front partition wall that covers the cabin and be provided with the gloves handle hole 06 of isolating with first operational window 4; Roll the second operational window 5 that the next door, back of covering the cabin is a manual work, and roll the back partition wall that covers the cabin and be provided with the gloves handle hole 06 of isolating with second operational window 5; Be positioned at and roll the place, left front corner of covering the cabin and be provided with by clear glass partition wall 05 and isolate the transferring cabin 6 that surrounds, and transferring cabin 6 is provided with Men Yujia operational window 4 and communicates; Being positioned between bottle outlet 3 partition wall place, the left side is provided with one and covers adjacent and adjacent with the front partition wall of the second operational window 5 technology passageway 04 that is used for aseptic isolation roughing-in purposes in cabin 2, first operational window 4 with rolling; Be laid with in the technology passageway and Cover-rolling machine bottom bonded assembly, by the ventilation and negative pressure ventilation pipe 23 of negative pressure induced wind machine driving.
Each job shop all is provided with baroceptor separately with the cabin and is connected with described control housing 03;
Be positioned at the right-hand of second operational window 5 front partition walls, be provided with plumbing connection of the same name separately in compressed-air cleaner 01, ozone generator 02 and the technology passageway 04; Be positioned at the left of second operational window 5 front partition walls, be provided with, each job shop and cabin air pressure are carried out control housing 03 automatic follow-up control, able to programme, preset control parameters by control ventilation and negative pressure ventilation pipe 23 air doors in each job shop and cabin; The roof portion in each job shop and cabin is equipped with the ventilation inlet of the high efficiency particle air filter 07 that is called as HEPA; The air outlet place that effluxes of ventilation and negative pressure ventilation pipe 23 is provided with solid particulate matter separated and collected device and the high efficiency particle air filter of being convenient to change 07;
Described Cover-rolling machine 7 is for carrying out the equipment that aluminium lid or aluminium-plastic cap roll the cap seal mouth automatically to the container of having jumped a queue; Cover-rolling machine is by sending a bottle buffering rotating disk 71, advance bottle rotating disk 72, rolling and cover rotating disk 73, bottle outlet rotating disk 74, bottle outlet dish 75, aluminium lid hopper 76 and constitute; Cover-rolling machine rolls the bottom of covering rotating disk 73 and is provided with table top slope 77, and the below on table top slope is provided with pipeline and links to each other with described ventilation and negative pressure ventilation pipe 23;
Cover-rolling machine 7 and each job shop and mutual alignment, cabin and annexation:
Bottle buffering rotating disk 71 that send of Cover-rolling machine 7 is located in the bottling department 1, is positioned at into bottleneck 21 places; Cover-rolling machine 7 advance bottle rotating disk 72, roll cover rotating disk 73, bottle outlet rotating disk 74 is located to roll and covers in the cabin 2; Wherein, advancing bottle rotating disk 72 is positioned at and rolls the left side of covering rotating disk 73, bottle outlet rotating disk 74 is positioned at and rolls the right of covering rotating disk 73, advances bottle rotating disk 72 and links to each other with bottle buffering rotating disk 71 that send that is positioned at bottling department 1 by advancing bottleneck 21, and bottle outlet rotating disk 74 links to each other with the bottle outlet dish 75 that is positioned between bottle outlet 3 by going out bottleneck 22; The bottle outlet dish 75 of Cover-rolling machine 7 is located between bottle outlet in 3, is positioned at bottleneck 22 places; The aluminium lid hopper 76 of Cover-rolling machine 7 is located in the transferring cabin 6;
The air pressure setting in each job shop and cabin:
During work, by control housing 03 control, each job shop with the control of cabin baric gradient by height to hanging down is, bottling department 1, rolls and covers between cabin 2, bottle outlet 3; That is, roll and cover the relative bottling departments 1 in cabin 2 and be negative pressure, roll that cover between the 2 relative bottle outlets of cabin 3 be malleation, 3 air pressure are minimum between bottle outlet, and air-flow is covered between cabin 2, bottle outlet 3 and mobilely effluxes through ventilation and negative pressure ventilation pipe 23 to rolling by bottling department 1.
Principle of work
During work, aluminium lid sterilized by manually delivering to the transferring cabin 6 aluminium lid hopper 76 of packing into, medicine bottle in bottling department 1 can tamponade, bottle buffering rotating disk 71 that send by Cover-rolling machine 7 enters to roll and covers cabin 2 from advancing bottleneck 21, send into to roll and cover rotating disk 73 and roll the cap seal mouth through advancing bottle rotating disk 72, leave to roll and cover cabin 2 and arrive between bottle outlets 3 bottle outlet dish 75 by going out bottleneck 22 through bottle outlet rotating disk 74 again; Roll and cover rotating disk 73 and roll the dirt bits that lid produces, cover rotating disk 73 belows by being located to roll, the pipeline that links to each other with table top slope 77 effluxes by described ventilation and negative pressure ventilation pipe 23;
The negative pressure separation principle
Extraneous air enters each job shop and cabin by the ventilation inlet that roof portion is provided with high efficiency particle air filter 07; Roll the air that covers the cabin, most of discharge through ventilation and negative pressure ventilation pipe 23, few part is discharged between bottle outlet 3 because of pressure reduction from going out bottleneck 22; Control housing 03 by to each job shop and cabin advance exhaust air rate control, baric gradient is controlled to be to low by height, bottling department 1, roll and cover between cabin 2, bottle outlet 3; That is, roll and cover the relative bottling departments 1 in cabin 2 and be negative pressure, roll that cover between the 2 relative bottle outlets of cabin 3 be malleation, 3 is minimum between bottle outlet, makes air-flow cover 3 nonreturn floies between cabin 2, bottle outlet by bottling department 1 to rolling; Thereby guarantee bottling department 1, roll the environment cleanliness that covers cabin 2.
During work, manually Cover-rolling machine is operated by gloves handle hole 06 and special tool, behind the end-of-job, close into bottleneck 21 and the valve that goes out bottleneck 22, manually by the pressurized air behind the compressed air filter 01 degerming filtering bacterium of gloves handle hole 06 usefulness to Cover-rolling machine 7 cleaning of blowing, dirt is considered to be worth doing and is effluxed by ventilation and negative pressure ventilation pipe 23; After the cleaning, open ozone generator 02 and carry out ozone sterilization.
Claims (1)
1. the sterile negative pressure isolation facility of a Cover-rolling machine, comprise bottling department (1), roll and cover (3) between cabin (2), bottle outlet, first operational window (4), second operational window (5), transferring cabin (6), Cover-rolling machine (7), it is characterized in that: described bottling department (1), roll and cover (3) between cabin (2), bottle outlet, first operational window (4), second operational window (5), transferring cabin (6) for isolate each job shop and the cabin that surrounds by transparent partition wall (05); Press the left-right and front-back orientation and describe, roll and cover cabin (2) for rolling the cabin of covering operation; Rolling the next door, the left side of covering the cabin is the bottling department (1) that is provided with the can operation of filling apparatus, and roll the left side partition wall that covers the cabin be provided with communicate with bottling department (1) advance bottleneck (21), and advance bottleneck and be provided with valve; Roll the next door, the right of covering the cabin for handling between the bottle outlet that seals the back finished product (3), and roll the right partition wall that covers the cabin be provided with bottle outlet between (3) communicate go out bottleneck (22), and go out bottleneck and be provided with valve; Rolling the next door, front of covering the cabin is the first operational window (4) of manual work, and rolls the front partition wall that covers the cabin and be provided with the gloves handle hole (06) of isolating with first operational window (4); Rolling the next door, back of covering the cabin is the second operational window (5) of manual work, and rolls the back partition wall that covers the cabin and be provided with the gloves handle hole (06) of isolating with second operational window (5); Be positioned at and roll the place, left front corner of covering the cabin and be provided with by clear glass partition wall (05) and isolate the transferring cabin (6) that surrounds, and transferring cabin (6) is provided with Men Yujia operational window (4) and communicates; The partition wall place, the left side that is positioned at (3) between bottle outlet be provided with one with roll cover cabin (2), first operational window (4) is adjacent and the technology passageway (04) that be used for aseptic isolation roughing-in purposes adjacent with the front partition wall of second operational window (5); Be laid with in the technology passageway and Cover-rolling machine bottom bonded assembly, by the ventilation and negative pressure ventilation pipe (23) of negative pressure induced wind machine driving;
Each job shop all is provided with baroceptor separately with the cabin and is connected with control housing (03); Be positioned at the right-hand of second operational window (5) front partition wall, be provided with plumbing connection of the same name separately in compressed-air cleaner (01), ozone generator (02) and the technology passageway (04); Be positioned at the left of second operational window (5) front partition wall, be provided with by the air door of control ventilation and negative pressure ventilation pipe (23), each job shop and cabin air pressure are carried out control housing (03) automatic follow-up control, able to programme, preset control parameters in each job shop and cabin; The roof portion in each job shop and cabin is equipped with the ventilation inlet of the high efficiency particle air filter (07) that is called as HEPA; The air outlet place that effluxes of ventilation and negative pressure ventilation pipe (23) is provided with solid particulate matter separated and collected device and the high efficiency particle air filter of being convenient to change (07);
Described Cover-rolling machine (7) is for carrying out the equipment that aluminium lid or aluminium-plastic cap roll the cap seal mouth automatically to the container of having jumped a queue; Cover-rolling machine is by sending a bottle buffering rotating disk (71), advance a bottle rotating disk (72), rolling and cover rotating disk (73), bottle outlet rotating disk (74), bottle outlet dish (75), aluminium lid hopper (76) formation; Cover-rolling machine rolls the bottom of covering rotating disk (73) and is provided with table top slope (77), and the below on table top slope is provided with pipeline and links to each other with described ventilation and negative pressure ventilation pipe (23);
Cover-rolling machine (7) and each job shop and mutual alignment, cabin and annexation:
Bottle buffering rotating disk (71) that send of Cover-rolling machine (7) is located in the bottling department (1), is positioned at into bottleneck (21) and locates; Cover-rolling machine (7) advance a bottle rotating disk (72), roll cover rotating disk (73), bottle outlet rotating disk (74) is located to roll and covers in the cabin (2); Wherein, advancing a bottle rotating disk (72) is positioned at and rolls the left side of covering rotating disk (73), bottle outlet rotating disk (74) is positioned at and rolls the right of covering rotating disk (73), advance a bottle rotating disk (72) and link to each other with bottle buffering rotating disk (71) that send that is positioned at bottling department (1) by advancing bottleneck (21), bottle outlet rotating disk (74) links to each other with the bottle outlet dish (75) that is positioned at (3) between bottle outlet by going out bottleneck (22); The bottle outlet dish (75) of Cover-rolling machine (7) is located between bottle outlet in (3), is positioned at bottleneck (22) and locates; The aluminium lid hopper (76) of Cover-rolling machine (7) is located in the transferring cabin (6);
Each job shop and cabin baric gradient are set to, and, bottling department (1), are rolled and cover between cabin (2), bottle outlet (3) to low by height; That is, roll cover cabin (2) relatively bottling department (1) be negative pressure, roll cover cabin (2) relatively between bottle outlet (3) be malleation, (3) air pressure is minimum between bottle outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101734837A CN101804958B (en) | 2010-04-29 | 2010-04-29 | Sterile negative pressure isolation facility of capping machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101734837A CN101804958B (en) | 2010-04-29 | 2010-04-29 | Sterile negative pressure isolation facility of capping machine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101804958A CN101804958A (en) | 2010-08-18 |
| CN101804958B true CN101804958B (en) | 2011-10-05 |
Family
ID=42606941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010101734837A Expired - Fee Related CN101804958B (en) | 2010-04-29 | 2010-04-29 | Sterile negative pressure isolation facility of capping machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101804958B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102115020A (en) * | 2010-09-27 | 2011-07-06 | 楚天科技股份有限公司 | Capping machine |
| CN102145871B (en) * | 2011-03-21 | 2012-08-29 | 楚天科技股份有限公司 | Capping machine |
| CN102219174B (en) * | 2011-05-10 | 2012-10-17 | 浙江卫信生物药业有限公司 | Dust removing device with air curtain separation and self-circulation purification |
| CN102381671A (en) * | 2011-09-14 | 2012-03-21 | 南京乐惠轻工装备制造有限公司 | Air purifying device for glass bottled draught beer filling line |
| CN102303724A (en) * | 2011-09-14 | 2012-01-04 | 南京乐惠轻工装备制造有限公司 | Air purifier applied in filling production line of draught beer can |
| CN102530324A (en) * | 2011-11-25 | 2012-07-04 | 杭州泰林生物技术设备有限公司 | Purification isolating device of aseptic powder needle split-charging production line |
| CN103641048A (en) * | 2013-12-11 | 2014-03-19 | 上海新旭发机械科技有限公司 | Cleaning and protecting system for plugging device |
| CN107126907A (en) * | 2016-02-26 | 2017-09-05 | 南京中硼联康医疗科技有限公司 | Pharmaceutical synthesis device |
| CN107459016A (en) * | 2017-09-19 | 2017-12-12 | 长沙市中制药机械有限公司 | Encapsulating device is washed in a kind of big transfusion of linear plastic bottle |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1071392A (en) * | 1991-10-09 | 1993-04-28 | 李华锋 | Machine for filling and closing of bottles |
| FR2691451A1 (en) * | 1992-05-21 | 1993-11-26 | Lavy Sa | Automatic container cleaning device, barrel tanks or the like. |
| CN2709414Y (en) * | 2004-06-11 | 2005-07-13 | 长沙锐信机械制造有限公司 | Liquid filling and sealing machine |
| CN101391734A (en) * | 2008-10-25 | 2009-03-25 | 江苏华宇飞凌包装机械有限公司 | Reverse cover eliminating apparatus |
| CN101580218A (en) * | 2009-06-11 | 2009-11-18 | 杭州保灵集团有限公司 | Filling and sealing machine of oral liquid and vial |
| CN101585504A (en) * | 2008-05-22 | 2009-11-25 | 上海索维机电设备有限公司 | Fully-automatic paint filling system |
-
2010
- 2010-04-29 CN CN2010101734837A patent/CN101804958B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1071392A (en) * | 1991-10-09 | 1993-04-28 | 李华锋 | Machine for filling and closing of bottles |
| FR2691451A1 (en) * | 1992-05-21 | 1993-11-26 | Lavy Sa | Automatic container cleaning device, barrel tanks or the like. |
| CN2709414Y (en) * | 2004-06-11 | 2005-07-13 | 长沙锐信机械制造有限公司 | Liquid filling and sealing machine |
| CN101585504A (en) * | 2008-05-22 | 2009-11-25 | 上海索维机电设备有限公司 | Fully-automatic paint filling system |
| CN101391734A (en) * | 2008-10-25 | 2009-03-25 | 江苏华宇飞凌包装机械有限公司 | Reverse cover eliminating apparatus |
| CN101580218A (en) * | 2009-06-11 | 2009-11-18 | 杭州保灵集团有限公司 | Filling and sealing machine of oral liquid and vial |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101804958A (en) | 2010-08-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101804958B (en) | Sterile negative pressure isolation facility of capping machine | |
| EP2703335A1 (en) | Apparatus for dust removal by air curtain isolation and self-circulation purification | |
| US5490546A (en) | Installation and method for transferring products flowing out under gravity | |
| CN106429151B (en) | A kind of automatic feed/discharge warehouse sampling system and method | |
| EP0684928B1 (en) | Apparatus for discharging flowable material | |
| AU765805B2 (en) | Apparatus and method for handling material | |
| CN203998161U (en) | A kind of enclosed charging device | |
| CN211317919U (en) | Full-automatic intelligent crushing instrument | |
| CN101367467B (en) | Bunker for collecting solid castoff in industrial production process and operation method thereof | |
| CN105689327A (en) | Outer cleaning equipment for packages | |
| CN207483314U (en) | Lid and online head space oxygen detection equipment are rolled in a kind of dustless vertical laminar flow isolation | |
| CN211543659U (en) | Multifunctional movable vertical laminar flow hood | |
| CN203294322U (en) | Automatic and intelligent packing device for rubber powder | |
| CN102101119B (en) | Dedusting system for sample making chamber | |
| CN205042520U (en) | Be suitable for concentrated clearance of wheat flour milling factory, hierarchical, recovery system | |
| CN104888539A (en) | Built-in dry dust pre-treatment device and working method | |
| CN202316473U (en) | Mobile cyclone dust remover | |
| JP4734238B2 (en) | Structure for sealing and isolating packaging equipment from the external environment | |
| CN116116329B (en) | Seasoning processing production line | |
| CN213474262U (en) | Material transfer device | |
| JPS6320653Y2 (en) | ||
| CN205435665U (en) | Whole grain device of totally closed over -and -under type | |
| CN204282886U (en) | A new kind of workshop | |
| CN202046862U (en) | Dust removing device with air curtain isolating and self-circulation purifying functions | |
| CN210063481U (en) | Dust collection system for fire extinguisher filling production line |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111005 Termination date: 20150429 |
|
| EXPY | Termination of patent right or utility model |