CN101543223A - Composition containing thiophonate-methyl and hexaconazole with bactericidal effect - Google Patents
Composition containing thiophonate-methyl and hexaconazole with bactericidal effect Download PDFInfo
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- CN101543223A CN101543223A CN200910020865A CN200910020865A CN101543223A CN 101543223 A CN101543223 A CN 101543223A CN 200910020865 A CN200910020865 A CN 200910020865A CN 200910020865 A CN200910020865 A CN 200910020865A CN 101543223 A CN101543223 A CN 101543223A
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- methyl
- thiophanate
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- 239000000203 mixture Substances 0.000 title claims abstract description 35
- 230000000844 anti-bacterial effect Effects 0.000 title claims description 20
- STMIIPIFODONDC-UHFFFAOYSA-N 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(O)(CCCC)CN1C=NC=N1 STMIIPIFODONDC-UHFFFAOYSA-N 0.000 title abstract description 10
- 201000010099 disease Diseases 0.000 claims abstract description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 14
- 240000007594 Oryza sativa Species 0.000 claims abstract description 7
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 7
- 235000009566 rice Nutrition 0.000 claims abstract description 7
- 239000005842 Thiophanate-methyl Substances 0.000 claims description 43
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 claims description 43
- 150000003851 azoles Chemical class 0.000 claims description 32
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- 239000000843 powder Substances 0.000 claims description 17
- -1 antifreeze Substances 0.000 claims description 15
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 12
- 235000011430 Malus pumila Nutrition 0.000 claims description 10
- 235000015103 Malus silvestris Nutrition 0.000 claims description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 10
- 239000002270 dispersing agent Substances 0.000 claims description 10
- 238000009736 wetting Methods 0.000 claims description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 9
- 239000000375 suspending agent Substances 0.000 claims description 9
- 239000000080 wetting agent Substances 0.000 claims description 9
- 238000009472 formulation Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 229920002472 Starch Polymers 0.000 claims description 6
- 239000013530 defoamer Substances 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 6
- 229920001296 polysiloxane Polymers 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000008107 starch Substances 0.000 claims description 6
- 235000019698 starch Nutrition 0.000 claims description 6
- 239000002562 thickening agent Substances 0.000 claims description 6
- 239000005995 Aluminium silicate Substances 0.000 claims description 5
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 5
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 5
- 240000006365 Vitis vinifera Species 0.000 claims description 5
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 235000012211 aluminium silicate Nutrition 0.000 claims description 5
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 5
- 235000013311 vegetables Nutrition 0.000 claims description 5
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 4
- 229920001732 Lignosulfonate Polymers 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 4
- 241000209140 Triticum Species 0.000 claims description 4
- 235000021307 Triticum Nutrition 0.000 claims description 4
- 230000002528 anti-freeze Effects 0.000 claims description 4
- 239000012752 auxiliary agent Substances 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 239000007859 condensation product Substances 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- 229920001285 xanthan gum Polymers 0.000 claims description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 3
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 239000000440 bentonite Substances 0.000 claims description 3
- 229910000278 bentonite Inorganic materials 0.000 claims description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229920005646 polycarboxylate Polymers 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 229940088417 precipitated calcium carbonate Drugs 0.000 claims description 3
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 3
- 241000255789 Bombyx mori Species 0.000 claims description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 2
- 240000003377 Shepherdia canadensis Species 0.000 claims description 2
- 235000018324 Shepherdia canadensis Nutrition 0.000 claims description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 2
- 150000004996 alkyl benzenes Chemical class 0.000 claims description 2
- 229960000892 attapulgite Drugs 0.000 claims description 2
- 229940077388 benzenesulfonate Drugs 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 150000007942 carboxylates Chemical class 0.000 claims description 2
- 229920006184 cellulose methylcellulose Polymers 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 2
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- 239000000194 fatty acid Substances 0.000 claims description 2
- 229930195729 fatty acid Natural products 0.000 claims description 2
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 2
- 229920000609 methyl cellulose Polymers 0.000 claims description 2
- 239000001923 methylcellulose Substances 0.000 claims description 2
- 229910052625 palygorskite Inorganic materials 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 235000021003 saturated fats Nutrition 0.000 claims description 2
- 229920002545 silicone oil Polymers 0.000 claims description 2
- 159000000000 sodium salts Chemical class 0.000 claims description 2
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 claims description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
- 229910021653 sulphate ion Inorganic materials 0.000 claims description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 206010039509 Scab Diseases 0.000 abstract description 4
- 235000014443 Pyrus communis Nutrition 0.000 abstract description 3
- 230000000855 fungicidal effect Effects 0.000 abstract description 3
- 239000000575 pesticide Substances 0.000 abstract description 3
- 241000510928 Erysiphe necator Species 0.000 abstract description 2
- 241000219998 Philenoptera violacea Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 12
- 244000141359 Malus pumila Species 0.000 description 9
- 239000002131 composite material Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 230000003902 lesion Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 5
- FBOUIAKEJMZPQG-BLXFFLACSA-N diniconazole-M Chemical compound C1=NC=NN1/C([C@H](O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1Cl FBOUIAKEJMZPQG-BLXFFLACSA-N 0.000 description 5
- 230000000857 drug effect Effects 0.000 description 5
- 230000002045 lasting effect Effects 0.000 description 5
- 239000004562 water dispersible granule Substances 0.000 description 5
- 230000003449 preventive effect Effects 0.000 description 4
- 244000215068 Acacia senegal Species 0.000 description 3
- 229920000084 Gum arabic Polymers 0.000 description 3
- 239000000205 acacia gum Substances 0.000 description 3
- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
- 235000013350 formula milk Nutrition 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 241000223600 Alternaria Species 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 240000008790 Musa x paradisiaca Species 0.000 description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 230000035613 defoliation Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 241000233679 Peronosporaceae Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 150000008052 alkyl sulfonates Chemical class 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 235000021015 bananas Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 238000000205 computational method Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
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- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
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- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a pesticides fungicide mixture comprising thiophonate-methyl and hexaconazole. The main active components comprise the thiophonate-methyl and the hexaconazole, and the weight ratio of the thiophonate-methyl and the hexaconazole is 10 to 80:1 to 20. The invention has obvious effect for preventing and curing apple leaf spot disease, pear scab, grape powdery mildew and rice sheath blight disease.
Description
Technical field:
The present invention proposes the combination sterilization composition that a kind of active ingredient is thiophanate-methyl and own azoles alcohol, be used to prevent and treat apple, grape, vegetables, wheat, all kinds of diseases of paddy rice.
Background technology:
Because the long-term single spot defoliation that the bactericide that uses certain type is prevented and treated apple tree that depends on of people, be easy to generate pesticide resistance to a great extent, cause the dosage of chemical bactericide sharply to increase, simultaneously environment is caused pollution to a great extent, also increased peasant's drug cost.
The objective of the invention is to by after thiophanate-methyl and own azoles alcohol are carried out being mixed of reasonable science, thereby obtain control apple, grape, vegetables, wheat, all kinds of diseases of paddy rice.Avoided because of with an organic solvent easily producing poisoning, big for environment pollution, difficult transportation and the problem of preserving, and then reduce peasant's use cost greatly, and has obvious role in synergism after thiophanate-methyl and own azoles alcohol are composite, control efficiency obviously is better than the single usefulness of single agent, and does not see the relevant report of thiophanate-methyl and the composite product of own azoles alcohol so far as yet.
Summary of the invention:
The objective of the invention is to propose a kind of thiophanate-methyl and the composite bactericidal composition of own azoles alcohol, it has obvious synergistic effect, has enlarged fungicidal spectrum simultaneously, has reduced use cost, to people and animals, Environmental security, to fruit tree, vegetables and the good bactericidal composition of cereal control efficiency.
The present invention realizes in the following manner:
Described bactericidal composition, preparation of compositions raw material weight percentage are thiophanate-methyl 10～80%, own azoles alcohol 1～20%, auxiliary agent and excipients 15～90%.
Described auxiliary agent and excipients comprise dispersant, wetting agent, thickener, antifreeze, defoamer, filler.
Described dispersant is selected from one or more in polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, DBSA, Nekal BX, wetting and penetrating agent F, alkylnaphthalene sulfonate, polyoxyethylene triphenylethylene phosphenylic acid salt, spaonin powder, silkworm excrement, the soapberry powder.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, the glycerine.
Described defoamer is selected from: one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
The formulation of described bactericidal composition is wetting powder, water dispersion granule or suspending agent.
When making wetting powder, the present composition comprises: thiophanate-methyl 10%～80%, own azoles alcohol 1%～20%, wetting agent 1～5%, dispersant 1～8%, filler surplus.
Above-mentioned formulation material is mixed, in stirred tank, evenly stir, behind airslide disintegrating mill, mixing, promptly can be made into the own azoles alcohol of thiophanate-methyl wetting powder.
The present composition comprises following group component composition when making the thiophanate-methyl diniconazole water dispersible granule: thiophanate-methyl 10%～80%, own azoles alcohol 1%～20%, wetting agent 1～8%, dispersant 1%～10%, disintegrant 1%～4%, filler surplus.
Formulation material is mixed, pulverize,, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis is made the thiophanate-methyl diniconazole water dispersible granule through mediating with micro jet.
The present composition comprises following group component composition when making the thiophanate-methyl hexaconazole suspending agent: thiophanate-methyl 10%～60%, own azoles alcohol 1%～15%, dispersant 3%～8%, antifreezing agent 1%～5%, thickener 0.1%～1%, defoamer 0.1%～0.5%, water surplus.
Back in the above-mentioned formulation material except that crossing all the other components of active ingredient, is mixed through high speed shear, adding active ingredient, ball milling is 2～3 hours in ball mill, makes particle diameter all below 5 μ m, makes the thiophanate-methyl hexaconazole suspending agent.
Described bactericidal composition is used to prevent and treat apple, grape, vegetables, wheat, all kinds of diseases of paddy rice.
The advantage of bactericidal composition of the present invention is: 1, the composite use of thiophanate-methyl and own azoles alcohol has enlarged fungicidal spectrum; 2, have synergistic function, control efficiency is better than the single usefulness of single agent; 3, not with an organic solvent, reduced pollution, improved safety the producer, transporter, user to environment; 4, a medicine is controlled more, has reduced access times and cost; 5, has the advantage that drug effect height, quick-acting are good, the lasting period is long; 6, it is effective to prevent and treat the resistance disease, and can effectively delay the generation of disease drug resistance.
Specific embodiment:
Below will describe, but the purposes of preventing and treating of the present invention is not limited thereto with specific embodiment.
The preparation of the own azoles alcohol of example 1:70% thiophanate-methyl wetting powder, each set of dispense compares by weight:
Thiophanate-methyl 64g (weight ratio 64%)
Own azoles alcohol 6g (weight ratio 6%)
Bay alcohol radical sodium sulphate 4g (weight ratio 4%)
Alkylsulfonate 8g (weight ratio 8%)
White carbon 8g (weight ratio 8%)
The kaolin surplus
Above-mentioned formulation material is mixed, in stirred tank, evenly stir, behind airslide disintegrating mill, mixing, promptly can be made into the own azoles alcohol of 70% thiophanate-methyl wetting powder.
The part by weight of thiophanate-methyl and own azoles alcohol can change between 50～69:1～20 (routine 52:18,65:5) in the present embodiment, and both total weight items are 70%, form new embodiment.
The own azoles of 70% thiophanate-methyl alcohol wetting powder control alternaria leaf spot of apple, dispenser is 3 times altogether, dispenser in per 7 days once, the following table of preventive effect behind the last medicine:
Thiophanate-methyl and own azoles alcohol has good quick-acting after composite as seen from the above table, and the lasting period is long, and preventive effect is apparently higher than contrasting single agent.In this tested effective dosage scope, to apple tree safety, medicament of the present invention also had certain control efficiency to apple scab.
The preparation of example 2:60% thiophanate-methyl diniconazole water dispersible granule, each set of dispense compares by weight:
Thiophanate-methyl 55g (weight ratio 55%)
Own azoles alcohol 5g (weight ratio 5%)
Lignosulfonates sodium 4g (weight ratio 4%)
Lauryl sodium sulfate 7g (weight ratio 7%)
Ammonium sulfate 4g (weight ratio 4%)
Starch 2g (weight ratio 2%)
The kaolin surplus
Formulation material is mixed, pulverize,, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis is made 60% thiophanate-methyl diniconazole water dispersible granule through mediating with micro jet.
The part by weight of thiophanate-methyl and own azoles alcohol can change between 40～59:1～20 (routine 42:18,50:10) in the present embodiment, and both total weight items are 60%, form new embodiment.
The own azoles of 60% thiophanate-methyl alcohol control grape powdery mildew, dispenser is 3 times altogether, dispenser in per 7 days once, 7 days, 14 days, 30 days preventive effects such as following table after the last dispenser:
Thiophanate-methyl and own azoles alcohol has good quick-acting after composite as seen from the above table, and the lasting period is long, and preventive effect is apparently higher than contrasting single agent.In this tested effective dosage scope, to grape safety, medicament of the present invention also had certain well control efficiency to downy mildew of garpe.
The preparation of example 3:50% thiophanate-methyl hexaconazole suspending agent, each set of dispense compares by weight:
Thiophanate-methyl 46g (weight ratio 46%)
Own azoles alcohol 4g (weight ratio 4%)
Polycarboxylate 5g (weight ratio 5%)
Ethylene glycol 2g (weight ratio 2%)
Aluminium-magnesium silicate 0.8g (weight ratio 0.8%)
Xanthans 0.1g (weight ratio 0.1%)
Silicone defoaming agent 0.1g (weight ratio 0.1%)
White carbon 1g (weight ratio 1%)
Water surplus
Back in the above-mentioned formulation material except that crossing all the other components of active ingredient, is mixed through high speed shear, adding active ingredient, ball milling is 2～3 hours in ball mill, makes particle diameter all below 5 μ m, makes 50% thiophanate-methyl hexaconazole suspending agent.
The part by weight of thiophanate-methyl and own azoles alcohol can change between 35～49:1～15 (routine 35:15,45:5) in the present embodiment, and both total weight items are 50%, form new embodiment.
50% thiophanate-methyl hexaconazole suspending agent is to the sigatoka test of pesticide effectiveness.
One, investigation method: take a sample 10 strain bananas tree of accidental sampling is taked in every sub-district, and every strain is looked into 10 from top to bottom and launched leaf fully, and every leaf accounts for leaf area with lesion area percentage is by following standard grading:
0 grade: anosis
1 grade: lesion area accounts for whole leaf area below 5%;
3 grades: lesion area accounts for whole leaf area 6%～15%;
5 grades: lesion area accounts for whole leaf area 16%～25%;
7 grades: lesion area accounts for whole leaf area 26%～50%;
9 grades: lesion area accounts for whole leaf area more than 50%;
Two, computational methods:
In the formula: Ck
0For the disease of clear water check plot before the medicine refers to;
Pt
0For the disease of medicament treatment region before the medicine refers to;
Ck
1For the disease of clear water check plot behind the medicine refers to;
Pt
1For the disease in chemicals treatment district behind the medicine refers to.
Three, the processing medicament is as shown in the table to sigatoka field control effectiveness test result:
As seen from the above table, making suspending agent after thiophanate-methyl and own azoles alcohol are composite prevents and treats sigatoka, compare with single agent, have the drug effect height, quick-acting is good, the advantage that lasting period is long, and to the target crop safety, in process of the test, medicament of the present invention is higher than 80% to 14 days control efficiency of banana freckle.
Embodiment 4: the own azoles of thiophanate-methyl alcohol wetting powder formula ratio and prevent and treat the pear scab drug effect
| Content | 50％ | 55％ | 60％ | 65％ |
| Thiophanate-methyl | 47g | 50g | 55g | 55g |
| Own azoles alcohol | 3g | 5g | 5g | 10g |
| Dispersant | Neopelex 5g | Sodium carboxymethylcellulose 8g | NNO6g | Lignosulfonates 8g |
| Wetting agent | The withered powder 1g of tea | Spaonin powder 3g | Draw back powder 3g | Wetting agent F5g |
| Filler | Kaolin 44g | White carbon 34g | White carbon 31g | Precipitated calcium carbonate 22g |
| Extension rate | 2000 times of liquid | 3000 times of liquid | 3000 times of liquid | 5000 times of liquid |
| Control efficiency | 89.12％ | 87.35％ | 93.25％ | 90.09％ |
Embodiment 5: thiophanate-methyl diniconazole water dispersible granule formula ratio and prevent and treat the rice sheath blight disease drug effect
| Content | 50％ | 55％ | 65％ | 70％ |
| Thiophanate-methyl | 48g | 52g | 60g | 60g |
| Own azoles alcohol | 2g | 3g | 5g | 10g |
| Dispersant | NNO 5g | Two sodium naphthasulfonate 5g | Carboxymethyl cellulose 5g | Sodium lignin sulfonate 5g |
| Wetting agent | The withered powder 3g of tea | Spaonin powder 3g | Neopelex 5g | Draw back powder 3g |
| Binding agent | Starch 1g | Gum Arabic 1g | Polyvinyl alcohol 2g | Starch 2g |
| Disintegrant | Citric acid 2g | Tartaric acid 3g | Succinic acid 3g | Adipic acid 4g |
| Filler | Kaolin 44g | Bentonite 37g | Diatomite 25g | Kaolin 16g |
| The preparation dosage | 45 gram/mus | 38 gram/mus | 25 gram/mus | 15 gram/mus |
| Control efficiency | 85.2％ | 89.4％ | 88.1％ | 90.8％ |
Embodiment 6: thiophanate-methyl hexaconazole suspending agent formula ratio and control alternaria leaf spot of apple drug effect
| Content | 40％ | 40％ | 45％ | 45％ |
| Thiophanate-methyl | 38g | 36g | 42g | 40g |
| Own azoles alcohol | 2g | 4g | 3g | 5g |
| Dispersant | Sodium lignin sulfonate 1g | NNO3g | Sodium lignin sulfonate 3g | Carboxymethyl cellulose 3g |
| Defoamer | Isooctyl acid 0.3g | Organic silicone 0.3g | Organic silicone 0.5g | Organic silicone 0.5g |
| Thickener | Gum Arabic 03g | Gum Arabic 0.4g | Starch 0.5g | Xanthans 0.1g, aluminium-magnesium silicate 0.8g |
| Antifreezing agent | Ethylene glycol 4g | Propane diols 3g | Polyethylene glycol 4g | Glycerine 4g |
| Water adds to | 100g | 100g | 100g | 100g |
| Extension rate | 1500 times of liquid | 2500 times of liquid | 2000 times of liquid | 3000 times of liquid |
| Control efficiency | 87.37％ | 88.45％ | 92.09％ | 94.69％ |
By above-mentioned experimental results show that; we are as can be seen thus; thiophanate-methyl and composite spot defoliation, pear scab, sigatoka, the rice sheath blight disease of preventing and treating apple tree of own azoles alcohol have specific action; not not with an organic solvent; good to environmental protection property, to warm blooded animal safety; compare with single agent, have tangible synergy and lasting effect.So research and extension of the present invention is used has crucial meaning.
Claims (10)
1, the present invention proposes a kind of bactericidal composition that contains thiophanate-methyl and own azoles alcohol, preparation of compositions raw material weight percentage is thiophanate-methyl 10～80%, own azoles alcohol 1～20%, auxiliary agent and excipients 15～90%.
2,, it is characterized in that its formulation is wetting powder, water dispersion granule or suspending agent according to right 1 described bactericidal composition.
3,, it is characterized in that described auxiliary agent and excipients comprise dispersant, wetting agent, thickener, antifreeze, defoamer, filler according to right 1 described bactericidal composition.
4,, it is characterized in that described dispersant is selected from one or more in polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO according to right 3 described bactericidal compositions.
5, according to right 3 described bactericidal compositions, it is characterized in that described wetting agent is selected from: one or more in lauryl sodium sulfate, DBSA, Nekal BX, wetting and penetrating agent F, alkylnaphthalene sulfonate, polyoxyethylene triphenylethylene phosphenylic acid salt, spaonin powder, silkworm excrement, the soapberry powder.
6,, it is characterized in that described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol according to right 3 described bactericidal compositions.
7,, it is characterized in that described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the urea according to right 3 described bactericidal compositions.
8, according to right 3 described bactericidal compositions, it is characterized in that described defoamer is selected from: one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
9,, it is characterized in that described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate according to right 3 described bactericidal compositions.
10, be used to prevent and treat apple, grape, vegetables, wheat, all kinds of diseases of paddy rice according to the described bactericidal composition of claim 1 to 10.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102599180A (en) * | 2012-02-24 | 2012-07-25 | 浙江威尔达化工有限公司 | Bactericidal composition and application thereof to rice sheath blight disease |
| CN103493835A (en) * | 2013-09-05 | 2014-01-08 | 江苏东宝农药化工有限公司 | Synergistic bactericide and preparation method thereof |
| CN105519523A (en) * | 2015-12-21 | 2016-04-27 | 河北省农林科学院石家庄果树研究所 | Composition containing evaporation reducing agent and sterilizing agent, and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101028009A (en) * | 2007-04-03 | 2007-09-05 | 盐城苏滨生物农化有限公司 | Caprotrahol and Bacillus subtilis compound agricultural chemicals |
| CN101103726A (en) * | 2007-08-14 | 2008-01-16 | 江苏龙灯化学有限公司 | Germicide composition containing thiophanate and tricyclazole |
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2009
- 2009-01-09 CN CN200910020865A patent/CN101543223A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101028009A (en) * | 2007-04-03 | 2007-09-05 | 盐城苏滨生物农化有限公司 | Caprotrahol and Bacillus subtilis compound agricultural chemicals |
| CN101103726A (en) * | 2007-08-14 | 2008-01-16 | 江苏龙灯化学有限公司 | Germicide composition containing thiophanate and tricyclazole |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102599180A (en) * | 2012-02-24 | 2012-07-25 | 浙江威尔达化工有限公司 | Bactericidal composition and application thereof to rice sheath blight disease |
| CN103493835A (en) * | 2013-09-05 | 2014-01-08 | 江苏东宝农药化工有限公司 | Synergistic bactericide and preparation method thereof |
| CN105519523A (en) * | 2015-12-21 | 2016-04-27 | 河北省农林科学院石家庄果树研究所 | Composition containing evaporation reducing agent and sterilizing agent, and preparation method and application thereof |
| CN105519523B (en) * | 2015-12-21 | 2018-06-29 | 河北省农林科学院石家庄果树研究所 | Composition, preparation method and application containing evaporation-reducing agent and fungicide |
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