CN101485839A - Chinese medicament preparation for preventing and treating children's malnutrition and preparation method thereof - Google Patents
Chinese medicament preparation for preventing and treating children's malnutrition and preparation method thereof Download PDFInfo
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- CN101485839A CN101485839A CN 200810056321 CN200810056321A CN101485839A CN 101485839 A CN101485839 A CN 101485839A CN 200810056321 CN200810056321 CN 200810056321 CN 200810056321 A CN200810056321 A CN 200810056321A CN 101485839 A CN101485839 A CN 101485839A
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Abstract
The invention relates to a traditional Chinese medicine preparation for preventing and treating infantile malnutrition and a preparation method thereof. The preparation is prepared by Atractylis ovata, hawthorn, malt, taro, mineral substances such as calcium, iron, zinc and the like, and vitamin A. The preparation has the efficacies of strengthening the spleen and the stomach, promoting digestion and eliminating indigestion, fixing the spleen and stopping diarrhea, can regulate dysfunction of the whole intestines, regulate intestinal flora, promote absorption and supplement deletion and deficiency of nutrient components of the body caused by the infantile malnutrition at the same time of preventing and treating children weakness of the spleen and the stomach and indigestion, has the effect of treating both symptoms and root causes for the infantile malnutrition, and has definite effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, particularly relate to a kind of be used to prevent and treat infantile malnutrition Chinese medicine preparation and preparation method thereof.
Background technology
Malnutrition is a kind of food deficiency disease due to heat or the protein for want of, so claim EMP again.Its Clinical symptoms is gradual becoming thin or edema, and subcutaneous fat reduces, weight loss or with the dysfunction in various degree of many organs.Underfed child reduces disease resistance, not only influences child's anthropometic, also influences its intelligence development simultaneously.
Along with improving constantly of people's living standard, usually the childhood dystrophy that causes because of hunger in the notion is rarely found, the result shows according to latest survey, 6 years old following child nutrition health status aggregate level turns for the better in China city, near WHO standard, but continuous progress along with society, people's life style, dietary habit, huge variation is also taking place in aspects such as dietary structure, though the childhood dystrophy sickness rate significantly reduces than eighties of last century is existing, because of child's dyspepsia, Bad Eating Habit, monophagia, the childhood dystrophy that anorexia and disease factor cause has been the main cause that causes that at present child nutrition lacks.
Report shows that China's urban children malnutrition rate is 26.43% according to investigations, and rural children malnutrition rate is 15.1%.More than the survey showed that, the whole society growth in the living standard, what particularly urban human all living creatures running water was flat improves constantly, child's dietary structure, dietary habit have been influenced, cause present childhood dystrophy disease situation occurred to be higher than the city by original rural area and change the city into and be higher than the rural area, its malnutrition mainly shows: the supply of nutrients such as nac protein, calcium, ferrum, zinc and vitamin A is obviously not enough.
At present, clinical treatment for childhood dystrophy still involves in the composition that has additional nutrients, control with spleen invigorating, help digestion, eliminate indigestion is purpose, but in recent years, the childhood dystrophy cause of disease changes to some extent, therefore, also should dialectical again opinion control on its therapeutic modality, in prevention and treatment, will carry out reasonable diet on the one hand childhood dystrophy, guarantee child's nutritive equilibrium, on the other hand, on original Therapeutic Principle basis, need to lack situation at present child nutrition, replenish the plain composition of appropriate nutrition, effectively to avoid influencing growth of children because of malnutrition.
Summary of the invention
One of the object of the invention is to provide a kind of Chinese medicine preparation with control infantile malnutrition, said preparation has the effect of invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation, stopping diarrhea with astringents, be used for childhood dystrophy due to prevention and treatment infantile dyspepsia, the inappetence, determined curative effect.
Two of the object of the invention is to provide the preparation method of this Chinese medicine preparation.
The traditional Chinese medical science claims that malnutrition is an infantile consumption, belongs to the spleen and stomach illness, often with strengthening the spleen and nourishing the stomach, and dyspepsia and intestinal stasis relieving, the treatment of methods such as invigorating qi and benefiting blood.
The effect that ancient literature record, the Rhizoma Atractylodis Macrocephalae have " strengthening the spleen and stomach, strong health " and improve body resistance against diseases, modern study shows that the Rhizoma Atractylodis Macrocephalae also has tangible strong effect, the effect of enhancing human body immunity power and bacteriostasis; Fructus Hordei Germinatus, Fructus Crataegi have circulation of qi promoting, help digestion, the appetite promoting and the spleen strengthening effect; Fructus Colocasiae Esculentae has stopping diarrhea with astringents, regulates intestinal microbial population, promotes the effect of absorption of nutrient ingredients and treatment infantile diarrhea.
The present invention is on the basis of Traditional Chinese medical theory treatment " infantile consumption ", generally lack calcium at modern malnourished children, ferrum, the clinical status of nutrient such as zinc and vitamin A, select the Rhizoma Atractylodis Macrocephalae for use, Fructus Hordei Germinatus, Fructus Crataegi, Fructus Colocasiae Esculentae is to reach invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation, the merit of stopping diarrhea with astringents, be equipped with calcium, ferrum, vitamin such as mineral cpd commonly used such as zinc and vitamin A, at prevention and treatment child weakness of the spleen and stomach, the dyspeptic while, in order to adjust bowel dysfunction, regulate intestinal microbial population, promote to absorb, and the additional body nutrient composition that causes because of childhood dystrophy lacks with not enough, childhood dystrophy had the merit for the treatment of both the principal and secondary aspects of a disease, definite effect.
A kind of Chinese medicine preparation of preventing and treating infantile malnutrition provided by the invention is characterized in that said preparation is to be made by following crude drug:
The Rhizoma Atractylodis Macrocephalae (stir-fry) 200～400 weight portion Fructus Crataegis 100～300 weight portion Fructus Hordei Germinatus (stir-fry) 100～300 weight portions
Fructus Colocasiae Esculentae 100～300 weight portion calcium 10～80 weight portion ferrum 1～8 weight portion
Zinc 1～8 weight portion vitamin A 0.09～0.3 weight portion
Used calcium was the calcium mineral materialization compound that can be used for food and medicine during raw material of the present invention was formed, as in calcium gluconate, calcium bicarbonate, calcium carbonate, calcium lactate, calcium acetate, calcium phosphate, calcium hydrogen phosphate, dalcium biphosphate, calcium citrate, calcium cirate malate, calcium malate, calcium caseinate, calcium sulfate, calcium ascorbate, the calcium glycerophosphate one or more; Used ferrum was the iron-bearing mineral materialization compound that can be used for food and medicine during raw material was formed, as in Ferrous gluconate, ferric ammonium citrate, iron chloride, ferric citrate, ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous sulfate, ferrous lactate, heme iron (iron porphyrin), protohemin, ferrous succinate, the ferric phrophosphate one or more; Used zinc was the zinc-bearing mineral materialization compound that can be used for food and medicine during raw material was formed, and comprised in zinc acetate, zinc carbonate, zinc chloride, zinc citrate, zinc gluconate, zinc lactate, zinc sulfate, the zinc oxide one or more.
Further, on the basis that said medicine is formed, the part by weight of the active drug composition of the Chinese medicine preparation that is used to prevent and treat infantile malnutrition of the present invention can be adopted as especially:
The Rhizoma Atractylodis Macrocephalae (stir-fry) 250 weight portion Fructus Crataegis 200 weight portion Fructus Hordei Germinatus (stir-fry) 200 weight portions
Fructus Colocasiae Esculentae 200 weight portion calcium 10 weight portion ferrum 1.5 weight portions
Zinc 1.5 weight portion vitamin A 0.1 weight portion
The preparation method of pharmaceutical preparation of the present invention is:
(1) get the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi powder is broken into coarse powder, adds Fructus Hordei Germinatus, adds 6～12 times of water gagings and decocts 2～4 times, each 1-3 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50～80 ℃), and is standby;
(2) get taro meal and be broken into coarse powder, add 8～12 times of water gagings and decoct 2 times, each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50～80 ℃), and is standby;
(3) get step 1. with step 2. the gained clear paste mix, zinc-bearing mineral materialization compound and vitamin A that other gets the calcium mineral materialization compound that is equivalent to required calcium amount in the proportioning raw materials, the iron-bearing mineral materialization compound that is equivalent to required ferrum amount in the proportioning raw materials, is equivalent to required zinc amount in the proportioning raw materials, formulation method is prepared into it in clinical acceptable drug preparations such as tablet, granule, syrup, effervescent tablet, chewable tablet routinely.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
Embodiment 1
(1) get Rhizoma Atractylodis Macrocephalae 50g, Fructus Crataegi 40g is ground into coarse powder, adds Fructus Hordei Germinatus 40g, adds 10 times of water gagings and decocts 2 hours, decocting liquid filters;
(2) medicinal residues add 8 times of water gagings, decoct 2 hours, and decocting liquid filters, and filtrate merges, and is concentrated into relative density and is the clear paste of 1.30 (50 ℃), and is standby;
(3) get Fructus Colocasiae Esculentae 40g and be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters;
(4) medicinal residues add 10 times of water gagings, decoct 1.5 hours, and decocting liquid filters, and filtrate merges, and are concentrated into relative density for inferior, and each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50 ℃), and is standby;
(5) above-mentioned clear paste merges, mix homogeneously, and other gets calcium gluconate 31.7g, Ferrous gluconate 2.7g, zinc gluconate 2.3g, vitamin A 0.02g and an amount of steviosin, sodium benzoate, citric acid, stirs evenly, and adds water to 1000ml, packing, promptly.
Embodiment 2
(1) get Rhizoma Atractylodis Macrocephalae 250g, Fructus Crataegi 200g is ground into coarse powder, adds Fructus Hordei Germinatus 200g, adds 10 times of water gagings and decocts 2 hours, decocting liquid filters;
(2) medicinal residues add 8 times of water gagings, decoct 2 hours, and decocting liquid filters, and filtrate merges, and is concentrated into relative density and is the clear paste of 1.30 (50 ℃), and is standby;
(3) get Fructus Colocasiae Esculentae 200g and be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters;
(4) medicinal residues add 10 times of water gagings, decoct 1.5 hours, and decocting liquid filters, and filtrate merges, and are concentrated into relative density for inferior, and each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50 ℃), and is standby;
(5) above-mentioned clear paste merges, and mix homogeneously is standby;
(6) get calcium gluconate 158.5g, Ferrous gluconate 13.5g, zinc gluconate 11.5g, vitamin A 0.1g and an amount of sucrose, add in the above-mentioned clear paste, mix homogeneously, drying is ground into fine powder, makes granule, drying, packing, promptly.
Embodiment 3
(1) get Rhizoma Atractylodis Macrocephalae 250g, Fructus Crataegi 200g is ground into coarse powder, adds Fructus Hordei Germinatus 200g, adds 10 times of water gagings and decocts 2 hours, decocting liquid filters;
(2) medicinal residues add 8 times of water gagings, decoct 2 hours, and decocting liquid filters, and filtrate merges, and is concentrated into relative density and is the clear paste of 1.30 (50 ℃), and is standby;
(3) get Fructus Colocasiae Esculentae 200g and be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters;
(4) medicinal residues add 10 times of water gagings, decoct 1.5 hours, and decocting liquid filters, and filtrate merges, and are concentrated into relative density for inferior, and each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50 ℃), and is standby;
(5) above-mentioned clear paste merges, and spray drying gets the extractum powder, and is standby;
(6) get calcium gluconate 158.5g, Ferrous gluconate 13.5g, zinc gluconate 11.5g, vitamin A 0.1g, add in the above-mentioned extractum powder, mix homogeneously, drying, sealing is preserved;
(7) get effervescent, sweeting agent and essence in addition, be ground into fine powder, drying is with above-mentioned fine powder mix homogeneously, direct compression, packing, promptly.
Claims (6)
1, a kind of Chinese medicine preparation that is used to prevent and treat infantile malnutrition is characterized in that said preparation is to be made by following crude drug:
The Rhizoma Atractylodis Macrocephalae (stir-fry) 200～400 weight portion Fructus Crataegis 100～300 weight portions
Fructus Hordei Germinatus (stir-fry) 100～300 weight portion Fructus Colocasiae Esculentaes 100～300 weight portions
Calcium 10～80 weight portion ferrum 1～8 weight portion
Zinc 1～8 weight portion vitamin A 0.09～0.3 weight portion
2, Chinese medicine preparation as claimed in claim 1 is characterized in that the part by weight of the active drug composition of this Chinese medicine preparation can be adopted as especially:
The Rhizoma Atractylodis Macrocephalae (stir-fry) 250 weight portion Fructus Crataegis 200 weight portion Fructus Hordei Germinatus (stir-fry) 200 weight portions
Fructus Colocasiae Esculentae 200 weight portion calcium 10 weight portion ferrum 1.5 weight portions
Zinc 1.5 weight portion vitamin A 0.1 weight portion
3, used calcium during raw material as claimed in claim 1 or 2 is formed, be characterized in that this raw material is the calcium mineral materialization compound that can be used for food and medicine, as in calcium gluconate, calcium bicarbonate, calcium carbonate, calcium lactate, calcium acetate, calcium phosphate, calcium hydrogen phosphate, dalcium biphosphate, calcium citrate, calcium cirate malate, calcium malate, calcium caseinate, calcium sulfate, calcium ascorbate, the calcium glycerophosphate one or more.
4, used ferrum during raw material as claimed in claim 1 or 2 is formed, be characterized in that this raw material is the iron-bearing mineral materialization compound that can be used for food and medicine, as in Ferrous gluconate, ferric ammonium citrate, iron chloride, ferric citrate, ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous sulfate, ferrous lactate, heme iron (iron porphyrin), protohemin, ferrous succinate, the ferric phrophosphate one or more.
5, used zinc during raw material as claimed in claim 1 or 2 is formed, be characterized in that this raw material is the zinc-bearing mineral materialization compound that can be used for food and medicine, comprise in zinc acetate, zinc carbonate, zinc chloride, zinc citrate, zinc gluconate, zinc lactate, zinc sulfate, the zinc oxide one or more.
6, the preparation method of Chinese medicine preparation as claimed in claim 1 or 2 is characterized in that this method is:
(1) get the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi powder is broken into coarse powder, adds Fructus Hordei Germinatus, adds 6～12 times of water gagings and decocts 2～4 times, each 1-3 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50～80 ℃), and is standby;
(2) get taro meal and be broken into coarse powder, add 8～12 times of water gagings and decoct 2 times, each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the clear paste that relative density is 1.20～1.30 (50～80 ℃), and is standby;
(3) get step 1. with step 2. the gained clear paste mix, zinc-bearing mineral materialization compound and vitamin A that other gets the calcium mineral materialization compound that is equivalent to required calcium amount in the proportioning raw materials, the iron-bearing mineral materialization compound that is equivalent to required ferrum amount in the proportioning raw materials, is equivalent to required zinc amount in the proportioning raw materials, formulation method is prepared into it in clinical acceptable drug preparations such as tablet, granule, syrup, effervescent tablet, chewable tablet routinely.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200810056321 CN101485839A (en) | 2008-01-16 | 2008-01-16 | Chinese medicament preparation for preventing and treating children's malnutrition and preparation method thereof |
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| CN 200810056321 CN101485839A (en) | 2008-01-16 | 2008-01-16 | Chinese medicament preparation for preventing and treating children's malnutrition and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735556A (en) * | 2013-11-21 | 2014-04-23 | 荣成百合生物技术有限公司 | Multivitamin mineral composite effervescent tablet and preparation method thereof |
| CN106819129A (en) * | 2016-12-21 | 2017-06-13 | 河南中医药大学 | A kind of children's invigorating the spleen promotees digestion milk piece and preparation method thereof |
| CN108851079A (en) * | 2018-08-27 | 2018-11-23 | 陕西鹤鸣健康科技有限公司 | A kind of compound preparation of enhancing development and preparation method thereof |
| EP3916127A1 (en) * | 2020-05-26 | 2021-12-01 | AloxX GmbH | Composition and method for inhibition of corrosion of metals or metal alloys |
-
2008
- 2008-01-16 CN CN 200810056321 patent/CN101485839A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735556A (en) * | 2013-11-21 | 2014-04-23 | 荣成百合生物技术有限公司 | Multivitamin mineral composite effervescent tablet and preparation method thereof |
| CN106819129A (en) * | 2016-12-21 | 2017-06-13 | 河南中医药大学 | A kind of children's invigorating the spleen promotees digestion milk piece and preparation method thereof |
| CN108851079A (en) * | 2018-08-27 | 2018-11-23 | 陕西鹤鸣健康科技有限公司 | A kind of compound preparation of enhancing development and preparation method thereof |
| EP3916127A1 (en) * | 2020-05-26 | 2021-12-01 | AloxX GmbH | Composition and method for inhibition of corrosion of metals or metal alloys |
| WO2021239685A1 (en) | 2020-05-26 | 2021-12-02 | Aloxx Gmbh | Use of a composition for inhibition of corrosion of metals or metal alloys and method for inhibition of corrosion of metals or metal alloys |
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Open date: 20090722 |