Four, the specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is elaborated.
Embodiment 1, the present invention is made by Radix Bupleuri 2.5g, Radix Salviae Miltiorrhizae 15g, Radix Scrophulariae 5.5g, Scorpio 5.5g, Pericarpium Citri Reticulatae 8g, Pericarpium Citri Reticulatae Viride 8g, Sanguis Draxonis 5.5g, Fructus Trichosanthis 21g, said medicine is dried respectively, pulverize, mixed-powder is crossed 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
Embodiment 2, the present invention is made by Radix Bupleuri 3g, Radix Salviae Miltiorrhizae 18g, Radix Scrophulariae 6g, Scorpio 6g, Pericarpium Citri Reticulatae 9g, Pericarpium Citri Reticulatae Viride 9g, Sanguis Draxonis 6g, Fructus Trichosanthis 24g, said medicine is dried respectively, pulverize, mixed-powder is crossed 100 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
Embodiment 3, the present invention can also be that Radix Bupleuri 3.5g, Radix Salviae Miltiorrhizae 20g, Radix Scrophulariae 6.5g, Scorpio 6.5g, Pericarpium Citri Reticulatae 10g, Pericarpium Citri Reticulatae Viride 10g, Sanguis Draxonis 6.5g, Fructus Trichosanthis 27g make, said medicine is dried respectively, pulverize, mixed-powder is crossed 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
The scientific compatible combination of said medicine supports to have the hard masses softening and resolving removing food stagnancy each other on function, the function of lactogenesis menstruation-regulating and speckle-dispelling just in time reaches effective treatment distending pain of the breast, cyclomastopathy, lump in breast, mammary gland fibroma, hysteromyoma, menoxenia, dysmenorrhea, mammary gland, menstruation and the skin disease of stagnation of QI causing phlegm retention blood stasis character such as chloasma, and proved that by clinical practice the concrete relevant clinical data of capsule of the present invention is as follows:
One, selects the standard of case
With cyclomastopathy and menoxenia is example:
Cyclomastopathy is meant breast epithelium and proliferation of fibrous tissue, is one of common gynecological disease.Can one-sided morbidity or bilateral fall ill simultaneously, the performance that cyclomastopathy is outstanding has lump in distending pain of the breast and the breast.
Menoxenia mainly is meant cycle, the menstrual period and unusual through what measure of menstruation, comprises epimenorrhea, i.e. the menstruation cycle is shorter than 21 days; Irregular menses, i.e. the menstruation cycle shifts to an earlier date 7 days or delays more than 7 days; Hypomenorrhea, i.e. the menstruation cycle was above 40 days; Menstrual period are long, and promptly menstrual period was above 7 days; Menorrhagia, i.e. menorrhagia; Hypomenorrhea, the front-month hypomenorrhea, even drop is promptly clean.
Two, diagnostic criteria
With cyclomastopathy and menoxenia is example:
The diagnostic criteria of cyclomastopathy is as follows:
1. single or multiple lumps appear in the one or both sides breast, and distending pain of the breast has obvious relation with emotion and menstrual cycle, can not alleviate in continuous three months;
2. get rid of the physiological mastalgia, the physiological mastalgia does not have the performance of breast lump;
3. can touch lump in the clinical health check-up breast, single or multiple, matter is tough, differs in size, and is irregular, multidigit in outside go up quadrant, lump and surrounding tissue do not have adhesion, can be pushed, the slight tenderness, the axillary lymph knot is not quite;
4. molybdenum target X line or color ultrasound are assisted diagnosis, go suction cytolgical examination of lump pin or local organization biopsy in case of necessity to make a definite diagnosis.
The diagnostic criteria of menoxenia is as follows:
1. epimenorrhea, menstrual cycle foreshortens to the person of promptly not rising about 20 days.
2. hypomenorrhea, menstrual cycle extended to more than 40 days, even 2~3 months persons of not rising once.
3. irregular menses is a tide about 20 days during menstrual cycle, the time be a tide about 40 days, successively do not have regularly.
4. menstrual period long, surpass 7 days menstrual period, very then the clean person of talent surplus in the of 10.
5.. menorrhagia, menstrual cycle, menstrual period are all normal, but menstrual blood volume showed increased more in the past, even along lower limb stream person.
6.. hypomenorrhea, menstrual cycle is normal, but menstrual blood volume more obviously reduces, obviously shortens menstrual period or drop is clean person.
Three, therapeutic scheme
The patient takes capsule of the present invention, and each 3~6, every day 2 times, the empty stomach warm water delivery service, per 2 weeks were 1 course of treatment.Observe clinical symptoms change before and after taking the present invention, judge curative effect.
Contraindication: menstrual period and pregnancy period forbidding.
Four, efficacy assessment standard
The criterion of therapeutical effect of cyclomastopathy:
1. complete obiteration of produce effects mammary gland tumor and mastalgia complete obiteration;
2. effective mammary gland tumor is dwindled more than 1/3 and mastalgia obviously alleviates;
3. invalid mammary gland tumor does not have significant change or mastalgia and does not have obviously and alleviate.
The criterion of therapeutical effect of menoxenia:
1. produce effects menstrual period, cycle, recover normal fully through the symptom of amount or dysmenorrhea;
2. effectively menstrual period, cycle, obviously alleviate through the symptom of amount or dysmenorrhea, and progressively alleviate more than two months;
3. invalid menstrual period, cycle, there is not obvious alleviator through the symptom of amount or dysmenorrhea.
Five, statistical disposition
By above-mentioned therapeutic scheme, diseases such as treatment cyclomastopathy or double menoxenia, wherein observe cyclomastopathy 947 examples, menoxenia 363 examples, the patient of 947 routine cyclomastopathy serves as to observe the time limit with the capsules for soothing depression and dissipating binds of the present invention of taking two courses of treatment all, in 947 routine patients of cyclomastopathy, there are 363 routine patients that the disease of menoxenia is arranged simultaneously, account for cyclomastopathy patient's 38.33%.These suffer from the patient of cyclomastopathy and two kinds of diseases of menoxenia simultaneously, and in the process of treatment cyclomastopathy, most of patient's menoxenia alleviates and alleviates with cyclomastopathy, and its total effective rate is respectively 98.34% and 94.54%.
Its result respectively as shown in Table 1 and Table 2.
The curative effect of table 1 capsules for soothing depression and dissipating binds treatment of the present invention cyclomastopathy
The curative effect of table 2 capsules for soothing depression and dissipating binds treatment of the present invention menoxenia
Among the 947 routine cyclomastopathy patients of clinical observation, there is the part patient to suffer from hysteromyoma simultaneously, also have the part patient to suffer from chloasma faciei simultaneously, the hysteromyoma that wherein has dwindles, the chloasma that has disappears, and illustrates that capsules for soothing depression and dissipating binds of the present invention can treat the multiple disease of cyclomastopathy, menoxenia, hysteromyoma and chloasma faciei to a certain extent simultaneously.
All take the patient of capsules for soothing depression and dissipating binds of the present invention, and at whole period in a medicine, none example occurs that the diarrhoea reaction appears in anaphylaxis, none example, uncomfortable reaction such as weak or poor appetite appears in none example; Part patient is through chemical examination monitorings such as routine blood test, routine urinalysis, stool routine, liver function and renal functioies before and after the treatment, and ANOMALOUS VARIATIONS appears in none example, and capsules for soothing depression and dissipating binds of the present invention is not only effective, and has no side effect, and is as safe as a house.
Observe from iconography, take the cyclomastopathy patient of capsules for soothing depression and dissipating binds of the present invention after two courses of treatment, its produce effects person's mammary gland luminous point become clear, even, yellowish orange, two newborn blood vessels are even, on slightly extend and attenuate smooth-shaped, nature out of shape to two lower limits, compare to the iconography before the treatment, its variation shows that cyclomastopathy recovered normal.
In sum, in the capsules for soothing depression and dissipating binds of the present invention, the Radix Bupleuri Pericarpium Citri Reticulatae Viride is with liver-smoothing, qi-regulating, and the Pericarpium Citri Reticulatae Fructus Trichosanthis is with eleminating phlegm and freeing channels, and the Radix Salviae Miltiorrhizae Sanguis Draxonis is with blood circulation promoting and blood stasis dispelling, and the Radix Scrophulariae Scorpio is with hard masses softening and resolving, and the Radix Bupleuri Radix Scrophulariae is with heat-clearing and toxic substances removing, Radix Scrophulariae Sanguis Draxonis invigorating kidney for regulating menstruation; Full side's scientific combination is supported hard masses softening and resolving removing food stagnancy, lactogenesis menstruation-regulating and speckle-dispelling mutually on the function, can be effective to treat distending pain of the breast, cyclomastopathy, lump in breast, mammary gland fibroma, hysteromyoma, menoxenia, dysmenorrhea, mammary gland, menstruation and the skin disease of stagnation of QI causing phlegm retention blood stasis character such as chloasma.The present invention is in conjunction with the clinical application experience, and the Chinese patent medicine preparation through scientific technology processes does not have irritated reaction and toxic and side effects to body.As Chinese medicine preparation, its medicine source is abundant, and preparation technology is easy, be easy to carry about with one, easy to use, inexpensive effect is good, treat wide, have no side effect, evident in efficacy, the succeeding in developing of capsules for soothing depression and dissipating binds of the present invention, clinical practice, apply, for numerous women remove misery, will produce good social benefit and economic benefit, be a creation on the Chinese medicine and pharmacy.