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CN101301412B - Shuyu Sanjie Capsules - Google Patents

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Publication number
CN101301412B
CN101301412B CN2008100500967A CN200810050096A CN101301412B CN 101301412 B CN101301412 B CN 101301412B CN 2008100500967 A CN2008100500967 A CN 2008100500967A CN 200810050096 A CN200810050096 A CN 200810050096A CN 101301412 B CN101301412 B CN 101301412B
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breast
capsules
pericarpium citri
citri reticulatae
radix
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CN101301412A (en
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鲁万强
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Abstract

本发明涉及疏郁散结胶囊,用于疏肝理气,醒脾化痰,祛瘀散结,补肾调经,可有效解决乳房胀痛,乳腺增生,乳房肿块,乳腺纤维瘤,子宫肌瘤,月经不调,痛经,黄褐斑等气滞痰阻血瘀性质的乳腺、月经及肌肤病症的问题,其解决的技术方案是,本发明胶囊是由柴胡2.5~3.5g、丹参15~20g、玄参5.5~6.5g、全蝎5.5~6.5g、陈皮8~10g、青皮8~10g、血竭5.5~6.5g、瓜蒌21~27g制成,将上述药物分别烘干,粉碎,混合粉末,过筛,装入胶囊,紫外线消毒即得。本发明药源丰富,制备工艺简便,易于携带,使用方便,价廉效佳,治疗面广,无副作用,其研究推广,有着良好的应用前景,必将产生较大的社会效益,并将为广大妇女解除痛苦。The invention relates to Shuyu Sanjie Capsules, which are used for soothing the liver and regulating qi, rejuvenating the spleen and resolving phlegm, dispelling blood stasis and dispelling stagnation, invigorating the kidney and regulating menstruation, and can effectively solve breast distending pain, breast hyperplasia, breast lump, breast fibroid, uterine fibroids, and irregular menstruation. Dysmenorrhea, breast, menstruation and skin diseases such as qi stagnation, phlegm and blood stasis properties such as chloasma, the technical solution is that the capsule of the present invention is composed of Bupleurum 2.5~3.5g, Salvia miltiorrhiza 15~20g, Scrophulariaceae 5.5-6.5g, 5.5-6.5g of scorpion, 8-10g of tangerine peel, 8-10g of green peel, 5.5-6.5g of dried blood, and 21-27g of Trichosanthes. Dry the above-mentioned medicines separately, crush them, mix the powder, and pass Sieve, pack into capsules, and sterilize with ultraviolet light. The present invention has rich sources of medicine, simple and convenient preparation process, easy to carry, convenient to use, low price and good effect, wide range of treatment, and no side effects. Its research and popularization have good application prospects, and will certainly produce greater social benefits, and will serve as The vast majority of women relieve pain.

Description

Capsules for soothing depression and dissipating binds
One, technical field
The present invention relates to medical domain, particularly a kind of capsules for soothing depression and dissipating binds.
Two, background technology
Breast symptom comprises that acute mastitis, chronic mastitis, cyclomastopathy, cyclomastopathy, cyclomastopathy, cystic hyperplasia of breast, mammary gland fibroma, tuberculosis of breast, breast are painful, distending pain of the breast, breast tumor and breast carcinoma etc. before and after the mastalgia, menstruation.Except breast carcinoma and part breast tumor, most of breast symptoms are optimum, but benign cyclomastopathy and fibroma also are converted into virulent possibility.Chinese medicine thinks that the mastotic cause of disease relates generally to factors such as emotion, diet, age, endocrine.Depressed rage impairing the liver is qi depression to blood stasis then; The worried impairment of the spleen is turbid interior the giving birth to of expectorant then; The retardance of the liver spleen expectorant stasis of blood is then dashed and is appointed the passages through which vital energy circulates imbalance; Involve in newborn network mammary gland, then cause cyclomastopathy, distending pain of the breast; Involve in the kidney channel vessels of the uterus, even then cause the menoxenia hysteromyoma; Cause in the stagnant heat toxin and accumulate, then cause diseases such as the yellowish-brown speckle of skin and manifest.In view of this, cyclomastopathy, hysteromyoma and yellowish-brown pinta are " different sick homology ".Since belong to different sick homology, need naturally " treating different diseases with the same therapeutic principle ".So how realize this purpose?
Three, summary of the invention
At above-mentioned situation, the present invention's purpose just is to provide a kind of capsules for soothing depression and dissipating binds, be used for depressed liver-energy dispersing and QI regulating, be amusing and reduce phlegm, eliminating stasis and resolving masses, invigorating kidney for regulating menstruation, can effectively solve distending pain of the breast, cyclomastopathy, lump in breast, mammary gland fibroma, hysteromyoma, menoxenia, dysmenorrhea, the mammary gland of stagnation of QI causing phlegm retention blood stasis character such as chloasma, the problem of menstruation and skin disease, the technical scheme of its solution is, capsule of the present invention is by Radix Bupleuri 2.5~3.5g, Radix Salviae Miltiorrhizae 15~20g, Radix Scrophulariae 5.5~6.5g, Scorpio 5.5~6.5g, Pericarpium Citri Reticulatae 8~10g, Pericarpium Citri Reticulatae Viride 8~10g, Sanguis Draxonis 5.5~6.5g, Fructus Trichosanthis 21~27g makes, and said medicine is dried respectively, pulverizes, mixed-powder, sieve, incapsulate, disinfection by ultraviolet light promptly.Medicine of the present invention source is abundant, and preparation technology is easy, is easy to carry about with one, and is easy to use, and inexpensive effect is good, treats widely, has no side effect, and its research promotion has good prospects for application, will produce bigger social benefit, and will remove misery for numerous women.
Four, the specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is elaborated.
Embodiment 1, the present invention is made by Radix Bupleuri 2.5g, Radix Salviae Miltiorrhizae 15g, Radix Scrophulariae 5.5g, Scorpio 5.5g, Pericarpium Citri Reticulatae 8g, Pericarpium Citri Reticulatae Viride 8g, Sanguis Draxonis 5.5g, Fructus Trichosanthis 21g, said medicine is dried respectively, pulverize, mixed-powder is crossed 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
Embodiment 2, the present invention is made by Radix Bupleuri 3g, Radix Salviae Miltiorrhizae 18g, Radix Scrophulariae 6g, Scorpio 6g, Pericarpium Citri Reticulatae 9g, Pericarpium Citri Reticulatae Viride 9g, Sanguis Draxonis 6g, Fructus Trichosanthis 24g, said medicine is dried respectively, pulverize, mixed-powder is crossed 100 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
Embodiment 3, the present invention can also be that Radix Bupleuri 3.5g, Radix Salviae Miltiorrhizae 20g, Radix Scrophulariae 6.5g, Scorpio 6.5g, Pericarpium Citri Reticulatae 10g, Pericarpium Citri Reticulatae Viride 10g, Sanguis Draxonis 6.5g, Fructus Trichosanthis 27g make, said medicine is dried respectively, pulverize, mixed-powder is crossed 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
The scientific compatible combination of said medicine supports to have the hard masses softening and resolving removing food stagnancy each other on function, the function of lactogenesis menstruation-regulating and speckle-dispelling just in time reaches effective treatment distending pain of the breast, cyclomastopathy, lump in breast, mammary gland fibroma, hysteromyoma, menoxenia, dysmenorrhea, mammary gland, menstruation and the skin disease of stagnation of QI causing phlegm retention blood stasis character such as chloasma, and proved that by clinical practice the concrete relevant clinical data of capsule of the present invention is as follows:
One, selects the standard of case
With cyclomastopathy and menoxenia is example:
Cyclomastopathy is meant breast epithelium and proliferation of fibrous tissue, is one of common gynecological disease.Can one-sided morbidity or bilateral fall ill simultaneously, the performance that cyclomastopathy is outstanding has lump in distending pain of the breast and the breast.
Menoxenia mainly is meant cycle, the menstrual period and unusual through what measure of menstruation, comprises epimenorrhea, i.e. the menstruation cycle is shorter than 21 days; Irregular menses, i.e. the menstruation cycle shifts to an earlier date 7 days or delays more than 7 days; Hypomenorrhea, i.e. the menstruation cycle was above 40 days; Menstrual period are long, and promptly menstrual period was above 7 days; Menorrhagia, i.e. menorrhagia; Hypomenorrhea, the front-month hypomenorrhea, even drop is promptly clean.
Two, diagnostic criteria
With cyclomastopathy and menoxenia is example:
The diagnostic criteria of cyclomastopathy is as follows:
1. single or multiple lumps appear in the one or both sides breast, and distending pain of the breast has obvious relation with emotion and menstrual cycle, can not alleviate in continuous three months;
2. get rid of the physiological mastalgia, the physiological mastalgia does not have the performance of breast lump;
3. can touch lump in the clinical health check-up breast, single or multiple, matter is tough, differs in size, and is irregular, multidigit in outside go up quadrant, lump and surrounding tissue do not have adhesion, can be pushed, the slight tenderness, the axillary lymph knot is not quite;
4. molybdenum target X line or color ultrasound are assisted diagnosis, go suction cytolgical examination of lump pin or local organization biopsy in case of necessity to make a definite diagnosis.
The diagnostic criteria of menoxenia is as follows:
1. epimenorrhea, menstrual cycle foreshortens to the person of promptly not rising about 20 days.
2. hypomenorrhea, menstrual cycle extended to more than 40 days, even 2~3 months persons of not rising once.
3. irregular menses is a tide about 20 days during menstrual cycle, the time be a tide about 40 days, successively do not have regularly.
4. menstrual period long, surpass 7 days menstrual period, very then the clean person of talent surplus in the of 10.
5.. menorrhagia, menstrual cycle, menstrual period are all normal, but menstrual blood volume showed increased more in the past, even along lower limb stream person.
6.. hypomenorrhea, menstrual cycle is normal, but menstrual blood volume more obviously reduces, obviously shortens menstrual period or drop is clean person.
Three, therapeutic scheme
The patient takes capsule of the present invention, and each 3~6, every day 2 times, the empty stomach warm water delivery service, per 2 weeks were 1 course of treatment.Observe clinical symptoms change before and after taking the present invention, judge curative effect.
Contraindication: menstrual period and pregnancy period forbidding.
Four, efficacy assessment standard
The criterion of therapeutical effect of cyclomastopathy:
1. complete obiteration of produce effects mammary gland tumor and mastalgia complete obiteration;
2. effective mammary gland tumor is dwindled more than 1/3 and mastalgia obviously alleviates;
3. invalid mammary gland tumor does not have significant change or mastalgia and does not have obviously and alleviate.
The criterion of therapeutical effect of menoxenia:
1. produce effects menstrual period, cycle, recover normal fully through the symptom of amount or dysmenorrhea;
2. effectively menstrual period, cycle, obviously alleviate through the symptom of amount or dysmenorrhea, and progressively alleviate more than two months;
3. invalid menstrual period, cycle, there is not obvious alleviator through the symptom of amount or dysmenorrhea.
Five, statistical disposition
By above-mentioned therapeutic scheme, diseases such as treatment cyclomastopathy or double menoxenia, wherein observe cyclomastopathy 947 examples, menoxenia 363 examples, the patient of 947 routine cyclomastopathy serves as to observe the time limit with the capsules for soothing depression and dissipating binds of the present invention of taking two courses of treatment all, in 947 routine patients of cyclomastopathy, there are 363 routine patients that the disease of menoxenia is arranged simultaneously, account for cyclomastopathy patient's 38.33%.These suffer from the patient of cyclomastopathy and two kinds of diseases of menoxenia simultaneously, and in the process of treatment cyclomastopathy, most of patient's menoxenia alleviates and alleviates with cyclomastopathy, and its total effective rate is respectively 98.34% and 94.54%.
Its result respectively as shown in Table 1 and Table 2.
The curative effect of table 1 capsules for soothing depression and dissipating binds treatment of the present invention cyclomastopathy
The curative effect of table 2 capsules for soothing depression and dissipating binds treatment of the present invention menoxenia
Figure GSB00000121854800042
Among the 947 routine cyclomastopathy patients of clinical observation, there is the part patient to suffer from hysteromyoma simultaneously, also have the part patient to suffer from chloasma faciei simultaneously, the hysteromyoma that wherein has dwindles, the chloasma that has disappears, and illustrates that capsules for soothing depression and dissipating binds of the present invention can treat the multiple disease of cyclomastopathy, menoxenia, hysteromyoma and chloasma faciei to a certain extent simultaneously.
All take the patient of capsules for soothing depression and dissipating binds of the present invention, and at whole period in a medicine, none example occurs that the diarrhoea reaction appears in anaphylaxis, none example, uncomfortable reaction such as weak or poor appetite appears in none example; Part patient is through chemical examination monitorings such as routine blood test, routine urinalysis, stool routine, liver function and renal functioies before and after the treatment, and ANOMALOUS VARIATIONS appears in none example, and capsules for soothing depression and dissipating binds of the present invention is not only effective, and has no side effect, and is as safe as a house.
Observe from iconography, take the cyclomastopathy patient of capsules for soothing depression and dissipating binds of the present invention after two courses of treatment, its produce effects person's mammary gland luminous point become clear, even, yellowish orange, two newborn blood vessels are even, on slightly extend and attenuate smooth-shaped, nature out of shape to two lower limits, compare to the iconography before the treatment, its variation shows that cyclomastopathy recovered normal.
In sum, in the capsules for soothing depression and dissipating binds of the present invention, the Radix Bupleuri Pericarpium Citri Reticulatae Viride is with liver-smoothing, qi-regulating, and the Pericarpium Citri Reticulatae Fructus Trichosanthis is with eleminating phlegm and freeing channels, and the Radix Salviae Miltiorrhizae Sanguis Draxonis is with blood circulation promoting and blood stasis dispelling, and the Radix Scrophulariae Scorpio is with hard masses softening and resolving, and the Radix Bupleuri Radix Scrophulariae is with heat-clearing and toxic substances removing, Radix Scrophulariae Sanguis Draxonis invigorating kidney for regulating menstruation; Full side's scientific combination is supported hard masses softening and resolving removing food stagnancy, lactogenesis menstruation-regulating and speckle-dispelling mutually on the function, can be effective to treat distending pain of the breast, cyclomastopathy, lump in breast, mammary gland fibroma, hysteromyoma, menoxenia, dysmenorrhea, mammary gland, menstruation and the skin disease of stagnation of QI causing phlegm retention blood stasis character such as chloasma.The present invention is in conjunction with the clinical application experience, and the Chinese patent medicine preparation through scientific technology processes does not have irritated reaction and toxic and side effects to body.As Chinese medicine preparation, its medicine source is abundant, and preparation technology is easy, be easy to carry about with one, easy to use, inexpensive effect is good, treat wide, have no side effect, evident in efficacy, the succeeding in developing of capsules for soothing depression and dissipating binds of the present invention, clinical practice, apply, for numerous women remove misery, will produce good social benefit and economic benefit, be a creation on the Chinese medicine and pharmacy.

Claims (4)

1. capsules for soothing depression and dissipating binds, it is characterized in that, make by Radix Bupleuri 2.5~3.5g, Radix Salviae Miltiorrhizae 15~20g, Radix Scrophulariae 5.5~6.5g, Scorpio 5.5~6.5g, Pericarpium Citri Reticulatae 8~10g, Pericarpium Citri Reticulatae Viride 8~10g, Sanguis Draxonis 5.5~6.5g, Fructus Trichosanthis 21~27g, said medicine is dried respectively, pulverize, mix, incapsulate.
2. capsules for soothing depression and dissipating binds according to claim 1, it is characterized in that, make by Radix Bupleuri 2.5g, Radix Salviae Miltiorrhizae 15g, Radix Scrophulariae 5.5g, Scorpio 5.5g, Pericarpium Citri Reticulatae 8g, Pericarpium Citri Reticulatae Viride 8g, Sanguis Draxonis 5.5g, Fructus Trichosanthis 21g, said medicine is dried respectively, pulverize, mix, cross 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
3. capsules for soothing depression and dissipating binds according to claim 1, it is characterized in that, make by Radix Bupleuri 3g, Radix Salviae Miltiorrhizae 18g, Radix Scrophulariae 6g, Scorpio 6g, Pericarpium Citri Reticulatae 9g, Pericarpium Citri Reticulatae Viride 9g, Sanguis Draxonis 6g, Fructus Trichosanthis 24g, said medicine is dried respectively, pulverize, mix, cross 100 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
4. capsules for soothing depression and dissipating binds according to claim 1, it is characterized in that, make by Radix Bupleuri 3.5g, Radix Salviae Miltiorrhizae 20g, Radix Scrophulariae 6.5g, Scorpio 6.5g, Pericarpium Citri Reticulatae 10g, Pericarpium Citri Reticulatae Viride 10g, Sanguis Draxonis 6.5g, Fructus Trichosanthis 27g, said medicine is dried respectively, pulverize, mix, cross 150 mesh sieves, the capsule of packing into No. 0, every content 0.5 gram, bottling back disinfection by ultraviolet light.
CN2008100500967A 2008-06-20 2008-06-20 Shuyu Sanjie Capsules Expired - Fee Related CN101301412B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104398713A (en) * 2014-11-14 2015-03-11 魏勤友 Chinese medicinal composition for eliminating breast lumps, breast hyperplasia and mastadenoma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家药品监督管理局.消乳散结胶囊.国家中成药标准汇编,中成药地方标准上升国家标准部分,外科妇科分册.2002,138. *

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Inventor after: Lu Wanqiang

Inventor after: Wang Huiqin

Inventor after: Zheng Jiao

Inventor before: Lu Wanqiang

Inventor before: Zheng Jiao

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: LU WANQIANG ZHENG JIAO TO: LU WANQIANG WANG HUIQIN ZHENG JIAO

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Granted publication date: 20100915

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