[go: up one dir, main page]

CN101263900B - Preparation of corn filament soft capsule - Google Patents

Preparation of corn filament soft capsule Download PDF

Info

Publication number
CN101263900B
CN101263900B CN2008100506357A CN200810050635A CN101263900B CN 101263900 B CN101263900 B CN 101263900B CN 2008100506357 A CN2008100506357 A CN 2008100506357A CN 200810050635 A CN200810050635 A CN 200810050635A CN 101263900 B CN101263900 B CN 101263900B
Authority
CN
China
Prior art keywords
corn silk
soft capsule
preparation
parts
corn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2008100506357A
Other languages
Chinese (zh)
Other versions
CN101263900A (en
Inventor
刘静波
林松毅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jilin University
Original Assignee
Jilin University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jilin University filed Critical Jilin University
Priority to CN2008100506357A priority Critical patent/CN101263900B/en
Publication of CN101263900A publication Critical patent/CN101263900A/en
Application granted granted Critical
Publication of CN101263900B publication Critical patent/CN101263900B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • General Preparation And Processing Of Foods (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

本发明的玉米花丝软胶囊及其制备方法属于功能食品加工的技术领域。玉米花丝软胶囊由囊化液和囊壳胶膜组成,组分包括玉米花丝粉、明胶、甘油、植物油、蜂蜡、维生素E、维生素C、色素、对羟基苯甲酸甲酯等。制备方法是以玉米花丝粉为主料;经玉米花丝粉制备、囊化液调配、囊壳胶膜制备、软胶囊丸制备的过程制得玉米花丝软胶囊。本发明有效利用玉米花丝资源,制得的玉米花丝软胶囊不但含有玉米花丝黄酮类、糖类、甾醇类等功效成分及其功效特性,而且还兼顾了软胶囊保健食品剂型所具有的饮用方便、贮藏方法简单、保质期长等特点,市场前景广阔。The corn silk soft capsule and the preparation method thereof of the present invention belong to the technical field of functional food processing. Corn silk soft capsule is composed of encapsulation liquid and capsule shell film, and its components include corn silk powder, gelatin, glycerin, vegetable oil, beeswax, vitamin E, vitamin C, pigment, methyl p-hydroxybenzoate, etc. The preparation method uses corn silk powder as the main ingredient; the corn silk soft capsule is prepared through the processes of preparation of corn silk powder, formulation of encapsulation solution, preparation of capsule shell film and preparation of soft capsule pills. The present invention effectively utilizes corn silk resources, and the prepared corn silk soft capsules not only contain corn silk flavonoids, sugars, sterols and other functional components and functional properties, but also take into account the convenience of drinking, the health food dosage form of soft capsules, The storage method is simple, the shelf life is long, etc., and the market prospect is broad.

Description

玉米花丝软胶囊的制备方法The preparation method of corn silk soft capsule

技术领域 technical field

本发明属于功能食品加工的技术领域,特别涉及玉米花丝赋型于软胶囊保健食品剂型的生产技术。  The invention belongs to the technical field of functional food processing, and in particular relates to the production technology of forming corn silk into the dosage form of soft capsule health food. the

背景技术 Background technique

玉米花丝是传统中药,含有甾醇类、糖类、黄酮类、有机酸、维生素、生物碱、皂苷、肌醇、隐黄质、尿囊素等多种功效成分,其药用价值主要体现在以下几个方面:  Corn silk is a traditional Chinese medicine, which contains sterols, sugars, flavonoids, organic acids, vitamins, alkaloids, saponins, inositol, cryptoxanthin, allantoin and other functional ingredients. Its medicinal value is mainly reflected in the following several aspects:

(1)降血糖、降血压、降血脂作用  (1) Lowering blood sugar, lowering blood pressure, lowering blood fat

《中药大辞典》记载,民间应用玉米花丝治疗糖尿病取得了较好的疗效。动物实验表明,玉米花丝多糖能够调节糖尿病小鼠的糖代谢,促进糖异生,对四氧嘧啶所至的血糖升高有明显降糖作用;玉米花丝总皂苷具有较好的降糖活性,对抗病因性糖尿病模型的胰岛损伤具有明显的保护作用,也是玉米花丝降糖的主要活性成分之一。此外,玉米花丝水提物对高血压具有明显的降压作用,而对血压正常者无影响。  "Dictionary of Chinese Medicine" records that the folk application of corn silk to treat diabetes has achieved good curative effect. Animal experiments have shown that corn silk polysaccharides can regulate glucose metabolism in diabetic mice, promote gluconeogenesis, and have a significant hypoglycemic effect on the increase in blood sugar caused by alloxan; corn silk total saponins have good hypoglycemic activity and can resist The islet injury of etiological diabetes model has obvious protective effect, and it is also one of the main active ingredients of corn silk for hypoglycemic effect. In addition, corn silk water extract has obvious antihypertensive effect on hypertension, but has no effect on normal blood pressure. the

(2)免疫调节作用  (2) Immunomodulatory effect

医学研究表明:机体组织细胞的凋亡、疾病的发生或多或少都与机体免疫系统的结构组成和免疫功能有关。如果正常机体的免疫系统不能对细胞的凋亡进行调控,相应组织器官就会发生病变,如肿瘤、肝炎。玉米花丝中含有的多糖、黄酮等功效成分安全无毒,具有较好免疫活性和抗氧化能力,能显著提高机体免疫力。主要表现为,缓解疲劳,抗肿瘤,抗衰老。  Medical research shows that the apoptosis of body tissue cells and the occurrence of diseases are more or less related to the structural composition and immune function of the body's immune system. If the immune system of the normal body cannot regulate the apoptosis of the cells, the corresponding tissues and organs will have pathological changes, such as tumors and hepatitis. The functional ingredients such as polysaccharides and flavonoids contained in corn silk are safe and non-toxic, have good immune activity and antioxidant capacity, and can significantly improve the body's immunity. The main performance is to relieve fatigue, anti-tumor, and anti-aging. the

(3)清热利胆作用  (3) The effect of clearing heat and promoting gallbladder

玉米花丝多糖能明显增强胆汁分泌量,促进胆囊收缩,降低胆囊重量,具有明显的清热利胆作用。  Corn silk polysaccharides can significantly increase bile secretion, promote gallbladder contraction, reduce gallbladder weight, and have obvious heat-clearing and choleretic effects. the

(4)利尿、通便,抑制结石作用  (4) Diuretic, laxative, and stone-inhibiting effects

玉米花丝水提物能延长胃排空时间,使肠蠕动加速,排便次数增加;降低肾草酸含量并抑制草酸钙结晶的形成,从而抑制草酸盐类结石的产生。  The aqueous extract of corn silk can prolong the gastric emptying time, accelerate intestinal peristalsis, and increase the frequency of defecation; reduce the content of oxalic acid in the kidney and inhibit the formation of calcium oxalate crystals, thereby inhibiting the generation of oxalate stones. the

此外,《中药大辞典》记载,玉米花丝低毒;美国食品药物管理局确认玉米花丝为安全、无毒的物质,且玉米花丝提取物所制药品也确认为非处方药。玉米花丝在美国已公认是安全的。  In addition, the "Dictionary of Traditional Chinese Medicine" records that corn silk is low in toxicity; the US Food and Drug Administration has confirmed that corn silk is a safe and non-toxic substance, and the medicine made from corn silk extract is also confirmed as an over-the-counter drug. Filigree corn has been recognized as safe in the United States. the

目前,国内外市场上还没有以玉米花丝为主要原料开发研制的软胶囊产品。  At present, there is no soft capsule product developed with corn silk as the main raw material in the domestic and foreign markets. the

发明内容 Contents of the invention

本发明要解决的技术问题是:公开一种玉米花丝软胶囊的组分及各组分含量,公开制备玉米花丝软胶囊的方法。本发明所研制的玉米花丝软胶囊不但含有玉米花丝黄酮类、糖类、甾醇类等功效成分及其功效特性,而且还兼顾了软胶囊保健食品剂型所具有的饮用方便、贮藏方法简单、保质期长等特点。  The technical problem to be solved by the invention is to disclose the components and the content of each component of a corn silk soft capsule, and disclose a method for preparing the corn silk soft capsule. The corn filament soft capsule developed by the present invention not only contains corn filament flavonoids, sugars, sterols and other functional components and their functional properties, but also takes into account the convenience of drinking, simple storage method and long shelf life of the soft capsule health food dosage form. Features. the

本发明采用的技术方案如下:  The technical scheme that the present invention adopts is as follows:

一种玉米花丝软胶囊,由囊化液和囊壳胶膜组成,其特征在于,以玉米花丝粉为主料,所述的囊化液各组分及其含量的质量份计为:玉米花丝粉9~20份、植物油80~91份、蜂蜡2~7.5份、维生素E 0.2~0.5份、维生素C 0~0.5份;所述的囊壳胶膜各组分及其按质量份计为:明胶2份、水0.2~0.3份、甘油0.6~1.5份、色素0.015~0.025份、对羟基苯甲酸甲酯0.005~0.015份。  A corn silk soft capsule, which is composed of an encapsulation liquid and a capsule shell film, is characterized in that corn silk powder is used as the main ingredient, and the mass parts of the components of the encapsulation liquid and their contents are: corn silk 9 to 20 parts of powder, 80 to 91 parts of vegetable oil, 2 to 7.5 parts of beeswax, 0.2 to 0.5 parts of vitamin E, and 0 to 0.5 parts of vitamin C; the components of the capsule shell film and their parts by mass are: 2 parts of gelatin, 0.2-0.3 parts of water, 0.6-1.5 parts of glycerin, 0.015-0.025 parts of pigment, 0.005-0.015 parts of methyl p-hydroxybenzoate. the

所述的玉米花丝粉,是玉米花丝经筛选、浸泡、清洗、烘干、粉碎得到的,颗粒度控制在70~200目。  The corn silk powder is obtained by screening, soaking, washing, drying and pulverizing the corn silk, and the particle size is controlled at 70-200 mesh. the

玉米花丝软胶囊的制备方法,以玉米花丝粉为主料;经玉米花丝粉制备、囊化液调配、囊壳胶膜制备、软胶囊丸制备的过程制得玉米花丝软胶囊;  The preparation method of the corn silk soft capsule is based on the corn silk powder; the corn silk soft capsule is prepared through the processes of preparation of corn silk powder, formulation of encapsulation solution, preparation of capsule shell film, and preparation of soft capsule pills;

所述的玉米花丝粉制备过程,是将玉米花丝剔除霉变部分,用水浸泡再流水冲洗反复操作2~4次,采用烘干粉碎或者湿料粉碎烘干至颗粒度在70~200目;  The preparation process of the corn filament powder is to remove the moldy part of the corn filament, soak it in water and then rinse it with running water for 2 to 4 times, and then use drying and crushing or wet material crushing and drying until the particle size is 70 to 200 mesh;

所述的囊化液调配过程,是将蜂蜡在70~90℃融化,按质量比例加入玉米花丝粉、植物油、维生素E、维生素C,在20~50℃搅拌使物料混合均匀,再经过胶体磨5~10次,20~50℃保温;  The preparation process of the encapsulation solution is to melt beeswax at 70-90°C, add corn silk powder, vegetable oil, vitamin E, and vitamin C according to the mass ratio, stir at 20-50°C to mix the materials evenly, and then pass through the colloid mill 5~10 times, keep warm at 20~50℃;

所述的囊壳胶膜制备过程,是按各组分质量比例明胶2份、水2份、甘油0.6~1.5份、色素0.015~0.025份、对羟基苯甲酸甲酯0.005~0.015份备料,先将明胶和水投入至真空溶胶桶中,经5~40分钟的浸泡使明胶膨胀,在50~80℃下搅拌溶解,再加入甘油、色素、对羟基苯甲酸甲酯,混匀后再通过软胶囊主机控制下制得囊壳胶膜;  The preparation process of the capsule shell film is to prepare materials according to the mass ratio of each component: 2 parts of gelatin, 2 parts of water, 0.6 to 1.5 parts of glycerin, 0.015 to 0.025 parts of pigment, and 0.005 to 0.015 parts of methyl p-hydroxybenzoate. Put the gelatin and water into the vacuum sol barrel, soak the gelatin for 5-40 minutes to expand the gelatin, stir and dissolve at 50-80°C, then add glycerin, pigment, methyl p-hydroxybenzoate, mix well and pass through the soft The capsule shell film is prepared under the control of the capsule host;

所述的软胶囊丸制备过程,是利用软胶囊机制备玉米花丝软胶囊丸,经定型、洗丸、晾丸、拣丸的过程制得成品。该过程于现有的胶囊丸剂食品的制丸过程相同。  The preparation process of the soft capsule pills is to use a soft capsule machine to prepare corn silk soft capsule pills, and to obtain finished products through the processes of setting the shape, washing the pills, drying the pills, and sorting the pills. This process is the same as the pill-making process of existing capsule pill food. the

在玉米花丝粉制备过程中,一般要浸泡冲洗2~4次,这是以农药残留各项指标控制在国家规定允许范围内为控制浸泡冲洗操作技术要点的;玉米花丝粉碎方式中,可以选用烘干粉碎或者选用湿料粉碎烘干的方式,至水分含量在3%~5%;若选用烘干粉碎时烘干温度应该控制在50℃~90℃,若选用湿料粉碎烘干时,烘干温度应该控制在40℃~80℃。  In the preparation process of corn silk powder, it is generally necessary to soak and rinse 2 to 4 times. This is to control the technical points of the soaking and washing operation by controlling the indicators of pesticide residues within the allowable range of national regulations; Dry crushing or wet material crushing and drying, until the moisture content is 3% to 5%; if drying and crushing is used, the drying temperature should be controlled at 50°C to 90°C; if wet material is crushed and dried, the drying temperature should be The drying temperature should be controlled between 40°C and 80°C. the

在囊化液调配过程中,胶体磨之后还可以进行7~15Mpa均质处理,使各组分混合得更均匀。  During the preparation process of the encapsulation solution, after the colloid mill, 7-15Mpa homogenization treatment can be carried out, so that the components can be mixed more evenly. the

在软胶囊丸制备过程中,更具体的可以是,利用软胶囊机制备玉米花丝软胶囊丸,输送至定型转炉中定型8~18小时;定型后浸于浓度为75%~95%乙醇中洗丸10~30秒;在相对湿度为35~45%、温度为21~25℃环境下晾丸10~24小时,之后检丸。检丸时,要剔除软胶囊丸形不均匀、不饱满的软胶囊丸。  In the soft capsule pill preparation process, it may be more specific to use a soft capsule machine to prepare corn silk soft capsule pills, and transport them to a shaping converter for shaping for 8 to 18 hours; Take the pills for 10-30 seconds; dry the pills for 10-24 hours in an environment with a relative humidity of 35-45% and a temperature of 21-25°C, and then check the pills. When inspecting the pills, the soft capsules with uneven and unfull shape should be rejected. the

吉林省是主要玉米产区,年种植面积达4000余万亩,除玉米及其精深加工产品研究开发外,对玉米须(玉米花丝)资源尚未有效利用,一般采取烧掉或废弃处理。所以,本发明开发玉米花丝软胶囊产品,能够将吉林省每年90余万吨玉米花丝作为功能食品新资源进行规模开发和利用,这将产生巨大的经济效益和社会效益。  Jilin Province is a major corn producing area, with an annual planting area of more than 40 million mu. Except for the research and development of corn and its deep-processing products, corn silk (corn silk) resources have not been effectively utilized, and are generally burned or discarded. Therefore, the invention develops the corn filament soft capsule product, which can use more than 900,000 tons of corn filament in Jilin Province as a new resource of functional food for large-scale development and utilization, which will generate huge economic and social benefits. the

本发明有效的利用了玉米花丝资源,所制得的玉米花丝软胶囊产品,不但含有玉米花丝黄酮类、糖类、甾醇类等功效成分及其功效特性,而且还兼顾了软胶囊保健食品剂型所具有的饮用方便、贮藏方法简单、保质期长等特点,真正体现出玉米花丝精深加工蕴涵的经济效益和社会效益,市场前景极其广阔。  The present invention effectively utilizes corn filament resources, and the prepared corn filament soft capsule product not only contains corn filament flavonoids, sugars, sterols and other functional ingredients and their functional properties, but also takes into account the health food formulations of soft capsules. It has the characteristics of convenient drinking, simple storage method and long shelf life, which truly reflects the economic and social benefits of deep processing of corn filigree, and has an extremely broad market prospect. the

具体实施方式 Detailed ways

实施例1:  Example 1:

取干玉米花丝剔除霉变部分,用水浸泡再流水冲洗反复操作2次,烘干至水分含量3%,粉碎至颗粒度90目;烘干时温度控制在80~90℃。  Take the dried corn filaments and remove the mildewed parts, soak them in water and rinse them with running water twice, dry them until the moisture content is 3%, and crush them to a particle size of 90 mesh; the temperature during drying is controlled at 80-90°C. the

将12g蜂蜡在70℃融化,加入玉米花丝粉80g、植物油320g、维生素E 2g,在50℃搅拌使物料混合均匀,再经过胶体磨10次,50℃保温,得到软胶囊的囊 化液。  Melt 12g of beeswax at 70°C, add 80g of corn silk powder, 320g of vegetable oil, and 2g of vitamin E, stir at 50°C to mix the materials evenly, then pass through a colloid mill 10 times, and keep warm at 50°C to obtain the encapsulation liquid of the soft capsule. the

将明胶80g、水80g投入至真空溶胶桶中,经40分钟的浸泡使明胶膨胀,在80℃下搅拌溶解,再加入甘油40g、对羟基苯甲酸甲酯0.2g、亮黑色素0.6g混合均匀,再通过软胶囊主机控制下制备囊壳胶膜。  Put 80g of gelatin and 80g of water into a vacuum sol bucket, soak the gelatin for 40 minutes to swell, stir and dissolve at 80°C, then add 40g of glycerin, 0.2g of methyl p-hydroxybenzoate, and 0.6g of bright melanin and mix evenly. Then the capsule shell film is prepared under the control of the soft capsule host. the

利用软胶囊机制备玉米花丝软胶囊丸,定型18h后,浸于75%乙醇中洗丸10秒后取出,并在21℃晾丸,控制相对湿度为45%,晾至24h后,剔除软胶囊丸形不均匀、不饱满的即为玉米花丝软胶囊成品。  Use a soft capsule machine to prepare corn silk soft capsule pills. After setting the shape for 18 hours, wash the pills in 75% ethanol for 10 seconds, take them out, and dry the pills at 21°C. Control the relative humidity at 45%. After drying for 24 hours, remove the soft capsules The ones with uneven and unfull shape are the finished corn silk soft capsules. the

实施例2  Example 2

取干玉米花丝60g,剔除霉变部分,用水浸泡再流水冲洗反复操作4次,烘干至水分含量5%,粉碎至颗粒度200目;烘干时温度控制在60~70℃。  Take 60g of dried corn filaments, remove the mildewed parts, soak in water and rinse with running water for 4 times, dry to a moisture content of 5%, and crush to a particle size of 200 mesh; the drying temperature is controlled at 60-70°C. the

将10g蜂蜡在90℃融化,加入玉米花丝粉40g、植物油358g、维生素E 1g、维生素C 1g,在40℃搅拌使物料混合均匀,再经过胶体磨8次,40℃保温,得到软胶囊的囊化液。  Melt 10g of beeswax at 90°C, add 40g of corn silk powder, 358g of vegetable oil, 1g of vitamin E, and 1g of vitamin C, stir at 40°C to mix the materials evenly, and then pass through the colloid mill 8 times, keep warm at 40°C, and obtain the capsule of the soft capsule liquid. the

先将明胶100g和水200g投入至真空溶胶桶中,经30分钟的浸泡使明胶膨胀,在60℃下搅拌溶解,再加入甘油50g、亮黑色素0.4g、对羟基苯甲酸甲酯0.6g,混匀后再通过软胶囊主机控制下制备囊壳胶膜。  First put 100g of gelatin and 200g of water into the vacuum sol bucket, soak the gelatin for 30 minutes to swell, stir and dissolve at 60°C, then add 50g of glycerin, 0.4g of bright melanin, 0.6g of methyl p-hydroxybenzoate, mix After uniformity, the capsule shell film is prepared under the control of the soft capsule host. the

利用软胶囊机制备玉米花丝软胶囊丸,定型8h后,浸于95%乙醇中洗丸30秒后取出,并在25℃晾丸,控制相对湿度为35%,晾至10h后,剔除软胶囊丸形不均匀、不饱满的即为玉米花丝软胶囊成品。  Use a soft capsule machine to prepare corn silk soft capsule pills. After setting the shape for 8 hours, soak the pills in 95% ethanol for 30 seconds, take them out, and dry the pills at 25°C. Control the relative humidity at 35%. After airing for 10 hours, remove the soft capsules The ones with uneven and unfull shape are the finished corn silk soft capsules. the

实施例3  Example 3

取干玉米花丝100g,剔除霉变部分,用水浸泡再流水冲洗反复操作3次,选用湿料粉碎烘干,颗粒度控制在100目,烘干温度应该控制在60℃。  Take 100g of dried corn filaments, remove the moldy part, soak in water and rinse with running water for 3 times, use wet materials to crush and dry, the particle size should be controlled at 100 mesh, and the drying temperature should be controlled at 60°C. the

将20g蜂蜡在70℃融化,加入玉米花丝粉60g、植物油380g、维生素E 2g、维生素C 2.2g,在40℃搅拌使物料混合均匀,再经过胶体磨5次,40℃保温,得到软胶囊的囊化液。  Melt 20g of beeswax at 70°C, add 60g of corn silk powder, 380g of vegetable oil, 2g of vitamin E, and 2.2g of vitamin C, stir at 40°C to mix the materials evenly, then pass through the colloid mill for 5 times, keep warm at 40°C, and obtain the soft capsule cystic fluid. the

先将明胶50g和水120g投入至真空溶胶桶中,经5分钟的浸泡使明胶膨胀,在80℃下搅拌溶解,再加入甘油50g、棕黄色素0.2g、对羟基苯甲酸甲酯0.3g,混匀后再通过软胶囊主机控制下制备囊壳胶膜。  First put 50g of gelatin and 120g of water into the vacuum sol bucket, soak the gelatin for 5 minutes to swell, stir and dissolve at 80°C, then add 50g of glycerin, 0.2g of buffy yellow pigment, and 0.3g of methyl p-hydroxybenzoate. After mixing evenly, the capsule shell film is prepared under the control of the soft capsule host. the

利用软胶囊机制备玉米花丝软胶囊丸,定型12h后,浸于85%乙醇中洗丸 20秒后取出,并在23℃晾丸,控制相对湿度为40%,晾至12h后,剔除软胶囊丸形不均匀、不饱满的即为玉米花丝软胶囊成品。  Use a soft capsule machine to prepare corn silk soft capsule pills. After setting the shape for 12 hours, soak the pills in 85% ethanol for 20 seconds, take them out, and dry the pills at 23°C with a relative humidity of 40%. After airing for 12 hours, remove the soft capsules The ones with uneven and unfull shape are the finished corn silk soft capsules. the

实施例4  Example 4

取干玉米花丝200g,剔除霉变部分,用水浸泡再流水冲洗反复操作4次,选用湿料粉碎烘干,颗粒度控制在80目,烘干温度应该控制在80℃。  Take 200g of dried corn filaments, remove the moldy part, soak in water and rinse with running water for 4 times, use wet materials to crush and dry, the particle size should be controlled at 80 mesh, and the drying temperature should be controlled at 80°C. the

将100g蜂蜡在80℃融化,加入玉米花丝粉150g、植物油1200g、维生素E5g、维生素C4g,在20℃搅拌使物料混合均匀,再经过胶体磨10次,20℃保温,得到软胶囊的囊化液。  Melt 100g of beeswax at 80°C, add 150g of corn silk powder, 1200g of vegetable oil, 5g of vitamin E, and 4g of vitamin C, stir at 20°C to mix the materials evenly, then pass through the colloid mill for 10 times, keep warm at 20°C, and obtain the encapsulation liquid of the soft capsule . the

先将明胶100g和水200g投入至真空溶胶桶中,经20分钟的浸泡使明胶膨胀,在50℃下搅拌溶解,再加入甘油30g、棕黄色素0.9g、对羟基苯甲酸甲酯0.8g,混匀后再通过软胶囊主机控制下制备囊壳胶膜。  First put 100g of gelatin and 200g of water into the vacuum sol bucket, soak the gelatin for 20 minutes to swell, stir and dissolve at 50°C, then add 30g of glycerin, 0.9g of brown yellow pigment, and 0.8g of methyl p-hydroxybenzoate. After mixing evenly, the capsule shell film is prepared under the control of the soft capsule host. the

利用软胶囊机制备玉米花丝软胶囊丸,定型10h后,浸于95%乙醇中洗丸30秒后取出,并在25℃晾丸,控制相对湿度为45%,晾至10h后,剔除软胶囊丸形不均匀、不饱满的即为玉米花丝软胶囊成品。  Use a soft capsule machine to prepare corn silk soft capsule pills. After setting the shape for 10 hours, soak the pills in 95% ethanol for 30 seconds, take them out, and dry the pills at 25°C. Control the relative humidity at 45%. After airing for 10 hours, remove the soft capsules The ones with uneven and unfull shape are the finished corn silk soft capsules. the

Claims (3)

1.一种玉米花丝软胶囊的制备方法,以玉米花丝粉为主料;经玉米花丝粉制备、囊化液调配、囊壳胶膜制备、软胶囊丸制备的过程制得玉米花丝软胶囊;1. A preparation method for corn silk soft capsules, which uses corn silk powder as the main ingredient; prepares corn silk soft capsules through the processes of corn silk powder preparation, encapsulation solution deployment, capsule shell film preparation, and soft capsule pill preparation; 所述的玉米花丝粉制备过程,是将玉米花丝剔除霉变部分,用水浸泡再流水冲洗反复操作2~4次,采用烘干粉碎或者湿料粉碎烘干至颗粒度在70~200目;The preparation process of the corn filament powder is to remove the moldy part of the corn filament, soak it in water and rinse it with running water for 2 to 4 times, and dry it by drying or wet material crushing until the particle size is 70 to 200 mesh; 所述的囊化液调配过程,是将蜂蜡在70~90℃融化,按质量比例加入玉米花丝粉、植物油、维生素E、维生素C,在20~50℃搅拌使物料混合均匀,再经过胶体磨5~10次,20~50℃保温;其中,囊化液各组分及其含量的质量份计为:玉米花丝粉9~20份、植物油80~91份、蜂蜡2~7.5份、维生素E 0.2~0.5份、维生素C 0~0.5份;The preparation process of the encapsulation solution is to melt beeswax at 70-90°C, add corn silk powder, vegetable oil, vitamin E, and vitamin C according to the mass ratio, stir at 20-50°C to mix the materials evenly, and then pass through the colloid mill 5-10 times, heat preservation at 20-50°C; among them, the mass parts of the components of the encapsulation liquid and their contents are: 9-20 parts of corn silk powder, 80-91 parts of vegetable oil, 2-7.5 parts of beeswax, vitamin E 0.2-0.5 parts, vitamin C 0-0.5 parts; 所述的囊壳胶膜制备过程,是按各组分质量比例明胶2份、水2份、甘油0.6~1.5份、色素0.015~0.025份、对羟基苯甲酸甲酯0.005~0.015份备料,先将明胶和水投入至真空溶胶桶中,经5~40分钟的浸泡使明胶膨胀,在50~80℃下搅拌溶解,再加入甘油、色素、对羟基苯甲酸甲酯,混匀后再通过软胶囊主机控制下制得囊壳胶膜;The preparation process of the capsule shell film is to prepare materials according to the mass ratio of each component: 2 parts of gelatin, 2 parts of water, 0.6 to 1.5 parts of glycerin, 0.015 to 0.025 parts of pigment, and 0.005 to 0.015 parts of methyl p-hydroxybenzoate. Put the gelatin and water into the vacuum sol barrel, soak the gelatin for 5-40 minutes to expand the gelatin, stir and dissolve at 50-80°C, then add glycerin, pigment, methyl p-hydroxybenzoate, mix well and pass through the soft The capsule shell film is prepared under the control of the capsule host; 所述的软胶囊丸制备过程,是利用软胶囊机制备玉米花丝软胶囊丸,经定型、洗丸、晾丸、拣丸的过程制得成品。The preparation process of the soft capsule pills is to use a soft capsule machine to prepare corn silk soft capsule pills, and to obtain finished products through the processes of setting the shape, washing the pills, drying the pills, and sorting the pills. 2.按照权利要求1所述的玉米花丝软胶囊的制备方法,其特征在于,所述的玉米花丝粉制备过程,烘干粉碎时烘干温度控制在50℃~90℃;湿料粉碎烘干时烘干温度控制在40℃~80℃。2. according to the preparation method of the corn silk soft capsule described in claim 1, it is characterized in that, described corn silk powder preparation process, drying temperature is controlled at 50 ℃~90 ℃ when drying and pulverizing; The drying temperature is controlled at 40°C to 80°C. 3.按照权利要求1或2所述的玉米花丝软胶囊的制备方法,其特征在于,所述的软胶囊丸制备过程,是利用软胶囊机制备玉米花丝软胶囊丸,输送至定型转炉中定型8~18小时;定型后浸于浓度为75%~95%乙醇中洗丸10~30秒;在相对湿度为35~45%、温度为21~25℃环境下晾丸10~24小时,之后检丸。3. according to the preparation method of the described corn silk soft capsule of claim 1 or 2, it is characterized in that, described soft capsule ball preparation process is to utilize soft capsule machine to prepare corn silk soft capsule ball, is transported to stereotypes in the shaping converter 8 to 18 hours; after finalizing the shape, soak the pellets in ethanol with a concentration of 75% to 95% for 10 to 30 seconds; dry the pellets at a relative humidity of 35 to 45% and a temperature of 21 to 25°C for 10 to 24 hours, then Check pills.
CN2008100506357A 2008-04-24 2008-04-24 Preparation of corn filament soft capsule Expired - Fee Related CN101263900B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008100506357A CN101263900B (en) 2008-04-24 2008-04-24 Preparation of corn filament soft capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2008100506357A CN101263900B (en) 2008-04-24 2008-04-24 Preparation of corn filament soft capsule

Publications (2)

Publication Number Publication Date
CN101263900A CN101263900A (en) 2008-09-17
CN101263900B true CN101263900B (en) 2012-01-11

Family

ID=39986786

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008100506357A Expired - Fee Related CN101263900B (en) 2008-04-24 2008-04-24 Preparation of corn filament soft capsule

Country Status (1)

Country Link
CN (1) CN101263900B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101897912A (en) * 2010-07-27 2010-12-01 浙江大学 A kind of bamboo shoot sterol soft capsule and its application
CN103355450A (en) * 2013-05-14 2013-10-23 吉林大学 A kind of preparation method of corn filament tea bag

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1742950A (en) * 2004-09-01 2006-03-08 闵伟红 Chinese medicine preparation made from corn stigma and preparing method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1742950A (en) * 2004-09-01 2006-03-08 闵伟红 Chinese medicine preparation made from corn stigma and preparing method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
范碧亭主编.第十三章 第二节 三 软胶囊剂的制法.《中药药剂学》.1997, *
鲁晓翔,陈甲,连喜军,张彦青.玉米须黄酮微胶囊制备条件的研究.《食品科学》.2007,第28卷(第9期),132-136. *

Also Published As

Publication number Publication date
CN101263900A (en) 2008-09-17

Similar Documents

Publication Publication Date Title
CN102846698B (en) Wall-broken radix tetrastigme oral decoction pieces
CN103736063B (en) A kind of medicated diet for damp-heat constitution conditioning and preparation method thereof
CN103355679A (en) Making method of chewable tablet with effect of enriching blood
CN103608024B (en) Control the pharmaceutical composition of blood glucose, blood fat and body weight
CN105596646A (en) Medicine, health-care product or food composition for controlling blood glucose and treating abnormal blood lipid metabolism
CN102552388B (en) Cyclocarya paliurus capsule and preparation method thereof
CN102599511B (en) Food therapy prescription for treating diabetes
CN104107269A (en) Functional blood sugar-reduction health product and preparation method thereof
CN109123351A (en) A kind of special doctor's food and preparation method with hyperglycemia population generation meal regulatory function
CN103223104B (en) A kind of Chinese medicine composition treating diabetes and preparation method thereof
CN101263900B (en) Preparation of corn filament soft capsule
CN110548120A (en) Traditional Chinese medicine soft extract for improving female climacteric symptoms and preparation method thereof
CN106109488A (en) The application in preparing the food or medicine with blood fat reducing function of a kind of Quinoa polysaccharide
CN105851764B (en) A kind of Qingqian Willow leaf solid beverage and its preparation method and application
CN102068475B (en) Application and blood-sugar lowering effective part of trapa acornis nakano shell as well as extraction method of blood-sugar lowering effective part
CN110326788A (en) A kind of bitter buckwheat d-chiro-inositol compound hypoglycemic tabletting and preparation method thereof
CN105148242A (en) Medicated diet for conditioning specific endowment constitution and preparation method thereof
CN108770970A (en) A kind of hypoglycemic instant coffee of blue or green money willow and preparation method thereof
CN102940182A (en) Low energy propolis hard capsule preparation method
CN103461980A (en) Health food with function of adjusting blood fat
CN105688146A (en) Healthcare capsule for improving sleeping quality
CN1853660A (en) Erigeron breviscapus preparation and making method thereof
CN101401849B (en) Uses of tea polyphenol traditional Chinese medicine compound in preparing medicament for reducing blood fat and blood sugar
CN105920053A (en) Preparation method of phellinus igniarius fine powder
CN101023969A (en) Hippophate flavone powder capsule and its preparing method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120111

Termination date: 20210424

CF01 Termination of patent right due to non-payment of annual fee