CN101253870A - Pesticide composition containing spinosad and carbamate insecticide - Google Patents

Abstract

The present invention relates to a pesticide composition, more specifically to a pesticide composition comprising a synergistically effective amount of spinosyn and a carbamate insecticide. Wherein the weight ratio of spinosyn to carbamate insecticide is preferably 1:0.1-1:200, more preferably 1:1-1:150, most preferably 1:19-1:139.

Description

Pesticide composition containing spinosad and carbamate insecticide

technical field

The invention relates to a synergistic pesticide composition, in particular to a synergistic pesticide composition comprising spinosyn and carbamate insecticides.

Background technique

Spinosyn (spinosad), also known as spinosad, is an intracellular secondary metabolite produced by aerobic fermentation of Saccharopolyspora actinomycetes (Saccharopolysporaspinosa), and its main active ingredient is spinosad Component A (spinosyn A) and component D (spinosyn D). Spinosad has good control effects on Lepidoptera and Diptera pests, especially against cotton bollworm, beet armyworm, litura, diamondback moth, rice stem borer, planthopper, thrips, etc. Active and fast-acting. Spinosyns are contact and stomach toxic to insects, by stimulating the nervous system of insects, resulting in non-functional muscle contraction, failure, accompanied by tremors and paralysis. This unique effect is consistent with activation of nicotinic acetylcholine receptors. So far, no product has been found that acts on the nervous system of insects in the same way.

Spinosad is mainly photodegraded and microbially degraded in the environment, and finally becomes carbon, hydrogen, oxygen, nitrogen, etc. Spinosad degrades rapidly, the half-life of soil photodegradation is 9-10d, the half-life of water photodegradation is less than 1d, and the half-life of leaf photodegradation is 1.6-16d. Spinosad has the characteristics of both the safety of biological pesticides and the rapidity of chemically synthesized pesticides. It has the advantages of low toxicity, low residue, natural enemies of insects, and beneficial biological safety. It has won the "Green Chemicals Challenge Award" of the US President for this reason.

In 2000, spinosad was approved to be used in more than 150 crops such as cotton, grains, fruits and vegetables in the United States. And registered in more than 30 other countries. Low toxicity to mammals and environmental friendliness, selectivity of insects and adaptability to integrated pest management, unique mechanism of action and resistance management characteristics plus excellent insect control effect, showing its huge market prospects and social benefits , It is expected to become a substitute product for many traditional pesticides.

Western flower thrips is a world-renowned dangerous pest, native to North America, first discovered in Kauai, Hawaii in 1955, and was once the most common thrips in California, USA. However, since the 1980s, it has become a more dominant species, with enhanced adaptability to different environments and increased resistance to insecticides, so it gradually expanded outwards. Up to now, western flower thrips has been distributed throughout the Americas, Europe, Asia, Africa, and Oceania, and has become a worldwide pest. Western flower thrips is extremely harmful to crops. The pest feeds on the stems, leaves, flowers, and fruits of the plants, causing the plants to wither, and also spreads various viral diseases including tomato spotted wilt virus. Moreover, Western flower thrips is omnivorous. At present, there are more than 500 known host plants, mainly plums, peaches, apples, grapes, strawberries, eggplants, peppers, lettuces, tomatoes, beans, orchids, chrysanthemums, etc. The number of host species has been continuously increasing. At present, western flower thrips has been introduced into my country and has become an invasive pest, which is causing serious damage to fruit trees, vegetables, flowers, etc. There is an urgent need to develop new agents, but there is currently no effective agent for the control of western flower thrips in China.

After a lot of research, the applicant found that the mixed use of spinosad and carbamate insecticides has an unexpected control effect on western flower thrips, and the synergistic effect is very obvious. Based on this finding, the applicants have completed the present invention.

Contents of the invention

The object of the present invention is to provide a synergistic pesticide composition with reasonable mixing, good control effect and low medication cost.

Another object of the present invention is to provide formulations such as emulsifiable concentrates, wettable powders, emulsions in water, and suspensions prepared from the synergistic pesticide composition.

Another object of the present invention is to provide the use of the synergistic pesticide composition for controlling western flower thrips.

Technical scheme of the present invention is as follows:

A pesticide composition is characterized in that it contains spinosyn and carbamate insecticides in synergistically effective doses.

In the aforementioned synergistic pesticide composition, the weight ratio of spinosyn to carbamate insecticide is preferably 1:0.1-1:200, more preferably 1:1-1:150, most preferably 1:19 -1:139. Among them, the carbamate insecticide is preferably carbosulfan, carbaryl or isoprocarb. The pesticide composition of the present invention can be formulated into dosage forms such as emulsifiable concentrate, wettable powder, water emulsion or suspension according to methods known to those skilled in the art.

Various auxiliary agents, solvents and carriers used in the preparation of the dosage form of the present invention are as follows:

Solvents and co-solvents: aromatic hydrocarbons, aliphatic hydrocarbons, ethers, phenols, alcohols, etc., such as benzene, petroleum ether, methanol, xylene, ethanol, n-butanol, toluene, isoamyl alcohol, ethyl acetate, tris Chloromethane, ethyl acetate, dichloromethane, kerosene, dimethyl sulfoxide, phenol, engine oil, etc. Wherein the solvent content usually accounts for 10-66wt%, and the co-solvent content usually accounts for 5-15wt%.

Emulsifiers and co-emulsifiers: fatty alcohol ethoxylates, alkylphenol ethoxylates, styrylphenol ethoxylates, alkylphenol ethoxylates sulfosuccinates, castor oil ethoxylates Ether, fatty acid polyoxyalkylene ester, alkyl aryl sulfonate, etc., such as 2201, Nongru 0203B, 0201B, 6202B, Nongru OX-2568, 500#, 600#, 700#, 6201, 602, 790, 1602, 1303, 603, etc. One or more emulsifiers can be mixed, but the total amount generally does not exceed 20wt%.

PH value adjusting agent: it can be sodium hydroxide, potassium hydroxide, hydrochloric acid, acetic acid, etc., and the content can be 0.5-1wt%.

Carrier (or filler): kaolin, activated clay, diatomaceous earth, peat, light calcium carbonate, white carbon black, pyrophyllite, talc, calcite, etc. It can be a mixture of one or more, but the total amount generally does not exceed 15-75wt%.

Dispersant: anionic dispersant, sulfurous acid pulp waste liquid, sodium lignosulfonate, calcium lignosulfonate, nonionic surfactant, etc., such as polyoxyethylene polyoxypropylene ether block copolymer, alkylphenol Polyoxyethylene phosphate, etc. It can be a mixture of one or more, but the total amount generally does not exceed 5-35wt%.

Wetting agent: natural products and anionic surfactants such as tea dry powder, saponin powder, SOPA (230, 270, 235), washing powder, sodium dodecylbenzene sulfonate, pull open powder, Nongru No. 2000 series, wetting and penetrating agent F, etc. It can be a mixture of one or more, but the total amount generally does not exceed 5-30wt%.

Stabilizer: urea, methanol, petroleum ether, wettable starch, cresyl glycidyl alcohol, etc. The dosage usually accounts for 0.5-10wt%.

Defoaming agent: it can be silicone oil, methanol, ethanol, epoxy soybean oil, etc.

Antifreeze: it can be glycerin, propylene glycol, ethylene glycol, sodium chloride, urea, glycerol, sorbitol, etc., and the dosage usually accounts for 1-8wt%

Binder: mainly soybean lecithin, gelatin, polyvinyl alcohol, polyethylene glycol, cyclodextrin, rosin, starch, etc. It can be a mixture of one or more, but the total amount generally does not exceed 1-10wt%.

Detailed ways:

The present invention will be further described below in conjunction with embodiment, but the present invention is by no means limited to following embodiment. The percentages of each component described in the examples refer to percentages by weight unless otherwise specified.

Preparation Example 1: Spinosad · Isoprocarb (Multi · Iso) wettable powder

The spinosad is pulverized with a jet mill first, then mixed with isoprocarb crude oil, then added with emulsifier, dispersant, wetting agent and filler, mixed thoroughly and then pulverized with a jet mill. The formulations of various ingredients in the wettable powder are spinosad 0.1-10%, isoprocarb 10-50%, emulsifier 1-10%, wetting agent 1-20%, dispersant 1-20%, and fillers are filled to 100%.

Preparation Example 2: Spinosyn Isoprocarb (Multiple Iso) Water Emulsion

Add the isoprocarb and spinosad into the solvent and co-solvent to completely dissolve the original drug, then add the emulsifier and stir to form a uniform oil phase. Add dispersant, antifreeze and defoamer to water under stirring to form a uniform water phase. With high speed stirring, pour the oil phase into the water phase. Forms a homogeneously dispersed emulsion in water. The formula of various ingredients in the aqueous emulsion is spinosad 0.5-20%, isoprocarb 20-35%, solvent 2-20%, emulsifier 1-8%, co-emulsifier 0.1-2%, dispersant 0.1- 2%, defoamer, antifreeze 2-8%.

Formulation Example 3: Spinosad Carbosulfan (Duo Ding) EC

Choose a suitable solvent to dissolve the original drug, if necessary, add a co-solvent, and then add an emulsifier and mix well. Among them, the content of spinosad is 0.5-2.5%, carbosulfan 19.5-49.5%, emulsifier 10-20%, methanol 5-10%, and xylene.

Formulation Example 4: Spinosyn Carbaryl (Multiple A) Suspension Concentrate

The components are 10-40% by weight of dispersant, 0.5-10% of thickener, 1-5% of antifreeze, 1-10% of defoamer, 1-10% of stabilizer, and 0.5-10% of spinosad. 50%, Carbaryl 20-60%. The specific method is to mix the original drug evenly, add the dispersant in proportion and stir fully, then add defoamer, thickener, stabilizer, antifreeze and deionized water in turn, stir evenly and grind to make the particle size below 4 μm. Can.

Biological Example 1: Combined Effects of Spinosyn and Carbamate Insecticides on Western Flower Thrips

Set different concentrations of liquid medicine, fill 3 1.5ml Tubes with each concentration of liquid medicine (3 repetitions), mark the corresponding control and treatment concentrations with a marker pen, pour out the liquid medicine after standing for 4 hours, and put the Tube tubes in place. Dry on the bench, ready to use.

Wash and dry the kale leaves. Dip in the liquid medicine for 10 seconds. Let dry and set aside.

Heat the tip of a thin needle with a length of about 10 cm through an alcohol lamp, pierce the bottom of the dried centrifuge tube, and iron a hole with a diameter of about 2-3 mm. Then fill the cap of the centrifuge tube with absorbent paper to absorb water during the experiment and keep the centrifuge tube from forming water droplets. Cut the dried cabbage leaves into 2cm×4cm rectangular strips, and use small tweezers to clamp them into centrifuge tubes dipped in the same concentration of the medicinal solution, one piece per tube, and place it flat.

Seal the interface of the vacuum pump with gauze, put it on the mouth of the centrifuge tube treated above, turn on the vacuum pump, adjust the air flow, and align the ironing hole at the bottom of the centrifuge tube with the western flower thrips, so that the insects can be sucked into the centrifuge tube along the air flow. Each tube sucks 10-20 heads of 2nd instar nymphs, then covers the tube cover, and seals the scalding hole with a parafilm. Store at 25°C for 1-4 days (the number of days varies with the quick-acting properties of the medicine).

Pour the worms and leaves in the centrifuge tube onto the white paper. Touch the worm body lightly with a brush, and it will be considered dead if it cannot crawl. Record the total number of tested insects and the number of dead insects. Indoor toxicity test results are as follows:

Table 1 Combined effect of spinosyn and carbamate insecticides on western flower thrips

The indoor measurement results showed that the mixed use of spinosad with carbamate insecticides carbaryl, carbosulfan, and isoprocarb had synergistic effects on western flower thrips.

Biological Example 2: Field efficacy test results

The test site is in a vegetable greenhouse in Xiaojiahe Village, Dongbeiwang Township, Haidian District, Beijing. The crop is cucumber, and the variety is Beijing No. 4. The experimental design adopts random block design, the area of the plot is 100m2, 4 repetitions, and the water consumption per mu is 50 liters. Investigation method: investigate 10 cucumbers in each plot, and investigate the number of living larvae of different ages on the whole plant. The survey base before spraying, and the number of residual insects were surveyed on the 1st, 3rd, and 7th days after spraying

The control effect of table 2 medicament to western flower thrips

Drug effect test shows that the prepared preparation of the present invention is more than 50%. Different wettable powder 30-40 grams/mu is obviously better than single agent 20% Isoprocarb emulsifiable concentrate 75 grams/mu treatment and 25 g/liter Caixi suspension concentrate 100 g/mu, the use cost is much lower than that of spinosad. Therefore, the mixture is worthy of application in the control of Western flower thrips.

Claims (7)

1. composition pesticide is characterized in that containing the pleocidin and the carbamate insecticide of synergy effective dose.

2. according to the composition pesticide of claim 1, the weight ratio that it is characterized in that pleocidin and carbamate insecticide is 1: 0.1-1: 200.

3. according to the composition pesticide of claim 1 or 2, the weight ratio that it is characterized in that pleocidin and carbamate insecticide is 1: 1-1: 150.

4. according to arbitrary composition pesticide of claim 1-3, the weight ratio that it is characterized in that pleocidin and carbamate insecticide is 1: 19-1: 139.

5. according to arbitrary composition pesticide of claim 1-4, it is characterized in that described carbamate insecticide is carbosulfan, carbaryl or Mobucin.

6. missible oil, wetting powder, aqueous emulsion or the suspending agent formulated according to the described composition pesticide of arbitrary claim of claim 1-5.

7. the purposes that the described composition pesticide of arbitrary claim of claim 1-6 is used to prevent and treat Frankliniella occidentalis.