CN100593412C - Chinese medicine composition for treating rheumatoid arthritis and method for preparing the same - Google Patents
Chinese medicine composition for treating rheumatoid arthritis and method for preparing the same Download PDFInfo
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Abstract
The present invention relates to a traditional Chinese medicine composition for the treatment of rheumatoid arthritis and the preparation method. The traditional Chinese medicine composition is composed of the substances with the following parts by weight: 5 to 10 parts of sabia japonica maxim, 2 to 6 parts of rehmannia radix, 1 to 2 parts of epimedium and 0.5 to 2 parts of ephedra herb. The traditional Chinese medicine composition overcomes the problems of complicated formulations of the traditional Chinese medicine, containing hormones and toxic components, easy to cause complications, great toxicity and side effects, not radically cure and easy recurrence in the prior art; while the formulation is simple, the treatment effective rate is high, and the diseases have no recurrence basically. When in preparation, the raw materials after drying over a fire are mixed according to the mix ratio by weight, smashed into the powder and passed through the 80 mesh screen.
Description
(1) technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of rheumatoid arthritis and preparation method thereof.
(2) background technology
Rheumatoid arthritis belongs to the traditional Chinese medical science " arthromyodynia " category.The arthromyodynia Clinical typing many based on wind, cold, wet, hot four types, wherein predominant wind to be apt to migration person be migratory arthralgia, predominant cold pain severe patient is an arthralgia aggravated by cold, the preponderance of dampness struttuer is a damp arthralgia, portion of steam win or whole body heating person are pyretic arthralgia.Rheumatoid main feature is an arthralgia, and migration is indefinite, and the sore spot frequent fever has the general character of damp and hot four numbness of wind and cold, and typing is difficult for.
At present the rheumatoid Chinese medicine of treatment is more, but the prescription complicated problems that exists more, and some also contains hormone and numerous toxic component, leads to complications easily, and not only toxic and side effects is big but also effect is also not obvious, perhaps can not effect a radical cure recurrence easily after the drug withdrawal.
(3) summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, prescription is simple, and the effective percentage height does not recur substantially.
The technical solution used in the present invention is as follows:
A kind of Chinese medicine composition for the treatment of rheumatoid arthritis is made up of following substances in parts by weight: 5～10 parts of Caulis Sinomenii, 2～6 parts in the Radix Rehmanniae, 1～2 part of Herba Epimedii, 0.5～2 part in Herba Ephedrae.
Further, described Chinese medicine composition is made up of following substances in parts by weight: 5 parts of Caulis Sinomenii, 2.5 parts in the Radix Rehmanniae, 1 part of Herba Epimedii, 0.5 part in Herba Ephedrae.
Perhaps weight is composed as follows: 8 parts of Caulis Sinomenii, 5 parts in the Radix Rehmanniae, 1.5 parts of Herba Epimedii, 0.8 part in Herba Ephedrae.
Perhaps weight is composed as follows: 10 parts of Caulis Sinomenii, 6 parts in the Radix Rehmanniae, 2 parts of Herba Epimedii, 1 part in Herba Ephedrae.
Caulis Sinomenii is bitter, hot, flat, slightly poisonous; Wind-damp dispelling, the meridian dredging, diuretic, pain relieving, dispelling the wind and dampness pathogens arthralgia pain, oncotic arthralgia of limbs are monarch drug.The Radix Rehmanniae, sweet, bitter, cool; Go into the heart, liver, kidney channel, clearing away heat and nourishing YIN, removing heat from blood is moisturized, and controls epidemic febrile disease heating, fever due to yin deficiency, quenches one's thirst, and is ministerial drug.Herba Epimedii, hot, sweet, warm; Go into liver, kidney channel, warming the kidney to activate YANG, expelling wind and removing dampness is controlled sexual impotence, premature ejaculation, senile chronic tracheitis, rheumatic arthralgia, is adjuvant drug.Herba Ephedrae, bitter, hot, warm, go into lung, urinary bladder channel, diaphoresis is relievingd asthma, diuretic, dispelling the wind and dampness pathogens flu, fever without perspiration, nephritis initial stage edema are messenger drug.The mild toxicity of Caulis Sinomenii greatly weakens under the mediation effect of other medicines.All medicines share, can not only wind-damp dispelling, and the meridian dredging, invigorating the liver and kidney simultaneously, bone and muscle strengthening.
The swollen place of the pain of rheumatoid arthritis has the heat of touching more or feels heat, and it is then light to meet heat, meet coldly then to weigh, active stage the rheumatoid multilist now be this kind of.The described heat of touching is meant that the doctor catches and touches patient's pain part skin hotness is arranged, and feels that heat is the conscious heating of patient's pain part.Chinese medicine composition simultaneously using both cold and hot drugs of the present invention, reinforcement and elimination in combination, cold relieving heat clearing away.
The present invention also provides a kind of preparation method of Chinese medicine composition of aforesaid treatment rheumatoid arthritis, described raw material is dried the weight proportion mixing of back according to 5～10 parts of Caulis Sinomenii, 2～6 parts in the Radix Rehmanniae, 1～2 part of Herba Epimedii, 0.5～2 part in Herba Ephedrae, be ground into powder, cross 80 mesh sieves.
Powder after sieving can be made the watered pill, also can also can make concentrated pill before use with being decocted in water for oral dose.
Generally according to each 10g, every day, 3 times amount was taken (the decocting dosing herewith) in the described Chinese medicine composition use, clothes in the middle of having a meal.Two months is a course of treatment, and take effect a general course of treatment, and take a turn for the better three courses of treatment.But in the use, diet chicken, pig, beef, Semen arachidis hypogaeae, Semen setariae, milk product; Prevention cold, humidity, exhaustion due to sexual indulgence, malnutrition, psychic trauma.
Described Chinese medicine composition is used for 120 routine rheumatoid arthritis patients treats, wherein male 45 examples, women 75 examples; Minimum 7 years old of age, maximum 64 years old; The course of disease is the shortest 3 months, and is the longest 20 years.
American Rheumatism Association's standard is adopted in the rheumatoid arthritis definition:
1) morning deadlock at least 1 hour, continue more than 6 weeks;
2) 3 or 3 above arthroncuss continue more than six weeks at least;
3) carpal joint, metacarpophalangeal joints or more than 6 weeks of near-end finger tip arthroncus;
4) symmetry arthroncus;
5) subcutaneous rheumatoid nodules;
6) the rheumatoid factor positive;
7) finger-joint X line changes confirmation.
Possess 4 or 4 above persons and be diagnosed as rheumatoid arthritis.
Criterion of therapeutical effect:
1. recovery from illness: painful, swollen, erythrocyte sedimentation rate, rheumatoid factor, five of functions are all normal;
2. produce effects: in above five four normal;
3. effective: in above five three normal.
4. take a turn for the better: have two in above five normally;
5. invalid: above five do not change.
Therapeutic outcome:
Example number recovery from illness produce effects is the invalid effective percentage of improvement effectively
120 40 46 22 6 6 95％
The present invention has following advantage with respect to prior art:
It is complicated that Chinese medicine composition of the present invention has overcome in the prior art Chinese medicine prescription, contains hormone and toxic component, leads to complications easily, the problem that toxic and side effects is big, can not effect a radical cure easy recurrence, and prescription is simple, and treatment effective percentage height does not recur substantially.
(4) specific embodiment:
Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:
Embodiment 1
Select high-quality Caulis Sinomenii, the Radix Rehmanniae, Herba Epimedii, Herba Ephedrae, after drying, get 10 parts of Caulis Sinomenii, 6 parts in the Radix Rehmanniae, 2 parts of Herba Epimedii, 1 part in Herba Ephedrae, cross 80 mesh sieves after being ground into powder, make the watered pill, be sub-packed in plastic bag, every bag of 100g dress.
Embodiment 2
Select high-quality Caulis Sinomenii, the Radix Rehmanniae, Herba Epimedii, Herba Ephedrae, after drying, get 5 parts of Caulis Sinomenii, 2.5 parts in the Radix Rehmanniae, 1 part of Herba Epimedii, 0.5 part in Herba Ephedrae, cross 80 mesh sieves after making powder, make the watered pill, be sub-packed in plastic bag, every bag of 100g dress.
Embodiment 3
Select high-quality Caulis Sinomenii, the Radix Rehmanniae, Herba Epimedii, Herba Ephedrae, after drying, get 8 parts of Caulis Sinomenii, 5 parts in the Radix Rehmanniae, 1.5 parts of Herba Epimedii, 0.8 part in Herba Ephedrae, cross 80 mesh sieves after making powder, make concentrated pill, be sub-packed in plastic bag, every bag of 100g dress.
Model case 1
Poplar, man, 23 years old, people from Heilungkiang.When JIUYUE was gone to a doctor on the 8th in 2004, dim complexion, the tongue fur center does not have, and coating colour is yellow greasy, and coating nature is thick, and sound is low, and rapid pulse is strong, and painful place's swelling of two knee joints and pain have the deadlock in morning, and Sleep hyperhidrosis has heating, and the course of disease is more than 2 years.The lab testing data are Hb:11.09/L, WBC:5.8 * 10
9/ L, DBC:5.8 * 10
9/ L, N:0.64L:0.35E:0.01; RF (-). advise it to take the watered pill that embodiment 1 makes, each 10g obeys in the meal every day three times, and erythrocyte sedimentation rate is normal during on March 15th, 06, and it is normal substantially to walk, and RG is heavy.After continuing to take half a year, all are normal, so far not recurrence.
Model case 2
The Wang, man, 59 years old.People from Hebei province.On January 11st, 07 went to a doctor.Left hand middle finger, right knee joint swell painful, painful 1 year of right scapulo-posterior.The deadlock in morning is arranged, and painful place chance heat is then light, meets cold and then weighs.RF(+)，ASO(-)，CPR(-)，ESR?9mm/h。Advise it to take the watered pill that embodiment 1 makes, each 10g, obeys in the meal at every day three times.On July 29th, 2007, medication is surplus half a year, and pain disappears, and swelling disappears, no morning deadlock.
Model case 3
Pacify certain, woman, 45 years old, people from Heilungkiang.Migration whole body after the trouble heel was painful in 2004 aches place's feel heat, touches heat, and chance heat is then gently met cold and then weighed.The time had palpitation, the eye have dry and astringent, insomnia and dreamful sleep, subcutaneous have a many places tuberosity, and big about 2 * 2cm has tenderness, sensation of aching, in stiff about 4～5 minutes of morning, pain is heavy light night in daytime, no amyotrophy, color of the lip is light red, erythrocyte sedimentation rate 120mm/h, c reactive protein (+), anti-" O " (+), rheumatoid factor (+), 37.6 ℃ of body temperature.General aching when on June 20th, 2006 went to a doctor, swollen painful 2 years of double knee joint, duplex, two ankle, both shoulders, clavicle, mandibular joint ache, and walking can not.Shallow complexion, shortness of breath and fatigue, arthroncus, morning deadlock, deformity of knee-joint, painful place touches heat, yellowish fur, rolling pulse.Advise it to take the watered pill that embodiment 1 makes, each 10g, obeys in the meal at every day three times.The back second day body temperature of taking medicine is normal, and diet does not hinder, and continues to take.Surplus January to medication on August 1 in 2006, sore spot heat is light, and the pain order of severity takes a turn for the better, can out-of-bed activity.After taking 1 year, pain disappears substantially, and swelling is clearly better, and before knee joint returns to distortion, can walk 4～6 li, and erythrocyte sedimentation rate is normal, and rheumatoid factor is still positive, stiff disappearance in morning, and life can be taken care of oneself.
Claims (6)
1. Chinese medicine composition for the treatment of rheumatoid arthritis is characterized in that described Chinese medicine composition is made up of the material of following parts by weight: 5～10 parts of Caulis Sinomenii, 2～6 parts in the Radix Rehmanniae, 1～2 part of Herba Epimedii, 0.5～2 part in Herba Ephedrae.
2. the Chinese medicine composition of treatment rheumatoid arthritis as claimed in claim 1 is characterized in that described Chinese medicine composition is made up of following substances in parts by weight: 5 parts of Caulis Sinomenii, 2.5 parts in the Radix Rehmanniae, 1 part of Herba Epimedii, 0.5 part in Herba Ephedrae.
3. the Chinese medicine composition of treatment rheumatoid arthritis as claimed in claim 1 is characterized in that described Chinese medicine composition is made up of following substances in parts by weight: 8 parts of Caulis Sinomenii, 5 parts in the Radix Rehmanniae, 1.5 parts of Herba Epimedii, 0.8 part in Herba Ephedrae.
4. the Chinese medicine composition of treatment rheumatoid arthritis as claimed in claim 1 is characterized in that described Chinese medicine composition is made up of following substances in parts by weight: 10 parts of Caulis Sinomenii, 6 parts in the Radix Rehmanniae, 2 parts of Herba Epimedii, 1 part in Herba Ephedrae.
5. the preparation method of the Chinese medicine composition of a treatment rheumatoid arthritis as claimed in claim 1 is characterized in that described raw material is dried the back to be mixed according to weight proportion, is ground into powder, crosses 80 mesh sieves.
6. preparation method for the treatment of the Chinese medicine composition watered pill of rheumatoid arthritis, it is characterized in that, after Caulis Sinomenii, the Radix Rehmanniae, Herba Epimedii, Herba Ephedrae dried, get 5～10 parts of Caulis Sinomenii, 2～6 parts in the Radix Rehmanniae, 1～2 part of Herba Epimedii, 0.5～2 part of mixing of Herba Ephedrae, be ground into powder, cross 80 mesh sieves, be prepared into the watered pill.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200710054941A CN100593412C (en) | 2007-08-13 | 2007-08-13 | Chinese medicine composition for treating rheumatoid arthritis and method for preparing the same |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200710054941A CN100593412C (en) | 2007-08-13 | 2007-08-13 | Chinese medicine composition for treating rheumatoid arthritis and method for preparing the same |
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| CN101112447A CN101112447A (en) | 2008-01-30 |
| CN100593412C true CN100593412C (en) | 2010-03-10 |
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| CN200710054941A Expired - Fee Related CN100593412C (en) | 2007-08-13 | 2007-08-13 | Chinese medicine composition for treating rheumatoid arthritis and method for preparing the same |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1175433A (en) * | 1996-08-30 | 1998-03-11 | 郭文钦 | Medicine for treating rheumatoid arthritis and its producing method |
| CN1276234A (en) * | 1999-06-05 | 2000-12-13 | 吴万年 | Medicine for treating rheumatism, rheumatoid, hyperosteogeny and arthritis and preparation method thereof |
-
2007
- 2007-08-13 CN CN200710054941A patent/CN100593412C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1175433A (en) * | 1996-08-30 | 1998-03-11 | 郭文钦 | Medicine for treating rheumatoid arthritis and its producing method |
| CN1276234A (en) * | 1999-06-05 | 2000-12-13 | 吴万年 | Medicine for treating rheumatism, rheumatoid, hyperosteogeny and arthritis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 痹痛宁胶囊的药理作用. 石扣兰，李利芬，杨立志，魏建丰，许维桢.中国药理与临床，第5卷第3期. 1989 |
| 痹痛宁胶囊的药理作用. 石扣兰，李利芬，杨立志，魏建丰，许维桢.中国药理与临床，第5卷第3期. 1989 * |
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