CN101579471B

CN101579471B - Medicine for curing diabetes

Info

Publication number: CN101579471B
Application number: CN200910065295XA
Authority: CN
Inventors: 毛嘉诚; 毛凌波; 毛凌云; 卢海珠; 刘杰; 毛顺卿; 毛嘉全
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-06-29
Filing date: 2009-06-29
Publication date: 2011-03-30
Anticipated expiration: 2029-06-29
Also published as: CN101579471A

Abstract

The invention relates to a medicine for curing diabetes. The raw materials for preparing the medicine mainly comprise ginseng, raidx astragali, radix trichosanthis, rehmannia root, rhizoma coptidis, rhizoma anemarrhenae, yam, tokay, fructus corni, salvia miltiorrhiza bunge, the larva of silkworm with botrytis and the like. In the invention, the monarch drug in the prescription is indispensable andthe ministerial drug, adjuvant and conductant drugs can be adjusted dialectically to prepare according the clinical condition. In a comprehensive view of the prescription, the components of the presc ription is reasonable, the compatibility of the medicine is proper, the source of the raw materials are abroad, the functions are accurate and special, the various components come in handy, nourishingthe energy source of the body for the governing function of the lung, and the lung is the upper source of water for governing clearing and regulating water passage; three Jiao is transported for acti vity of vital energy; The central organs are mediated for elevation and subsiding; Yin und Yang are regulated for constant breathing; the medicine has the efficiency of supplementing qi and nourishingyin, promote the secretion and nourishing the lung, nourishing the stomach to improve the production of body fluid, moistening lung and nourishing the kidney, and consolidating constitution and recov ering the health. Dosage forms such as oral solution, pill, tablet, powder, capsule and the like can be produced by the prescription, and the invention is convenient in use, is effective for treating diabetes and accompanying symptoms and is low in treatment cost.

Description

The medicine of treatment traditional Chinese medical science diabete

Technical field

The present invention relates to a kind of pharmaceutical composition, particularly a kind of medicine for the treatment of traditional Chinese medical science diabete.

Background technology

Chinese medicine think quench one's thirst be with excessive thirst, polydipsia, polyphagia, polyuria, it is tired that to become thin, urinate pleasantly sweet be the disease of classical symptom, the diabetes that are equivalent to modern medicine, be a kind of be the common incretion metabolism disease of common trait with the hyperglycemia, absolute or relative deficiency causes owing to insulin.Chinese medicine thinks that quenching one's thirst is because of the five internal organs natural endowment fragility, and it is scorching to be added with the internal organs deficiency of YIN that inducements such as disorder of emotion, eating and drinking without temperance cause, deficiency of both QI and YIN, and body fluid is failed the not normal a kind of disease of cloth.This patient is in the majority with middle-aged and elderly people, disease such as that the person of being in a bad way can cause is pained, dizzy, apoplexy, numbness, carbuncle.Diabete (diabetes) is because carbohydrate metabolism disturbance and the nervus vasculairs complication that causes therefrom and the corresponding many organ injuries that defect of insulin secretion and insulin resistant are caused, and severe complications such as ketoacidosis, hypoglycemia and trunk, blood capillary and peripheral vessels neuropathy often take place diabetes.With non-diabetic physiognomy ratio, diabetes patient's cardiovascular and cerebrovascular disease, blind sickness rate and mortality rate thereof are all high 2～5 times, and ulcer of the lower limb and amputation rate exceed 20 times especially.Economically developed along with China, the affluence of people's life, the diabetes prevalence of China increases year by year: 1979 is 0.67%, and nineteen ninety is that 3.21%, 1995～1997 years male diabetes prevalences are 3.40%, and sending out a property is 3.79%.In less than the time in 20 years, from low sick rate (＜3%) country, stride into the national ranks of the medium prevalence in the world (3～10%) rapidly.Estimate that diabetics reaches more than 2,000 ten thousand more than 20 years old, glucose tolerance attenuating person is lower than 30,000,000.Whole nation diabetes total number of persons is only second to India, occupies the second place of the world.At present, diabetes have become the third-largest non-infective disease after cardiovascular disease and tumor, are the worldwide public health problems of serious threat human health.

China has just had the understanding of some to the epidemiology of diabetes, etiology etc. as far back as the first two century in Christian era, as " husband pines for; the middle person that disappears, and all rich and honour people also " of " element ask in the abdomen opinion ", have in " element is asked strange sick opinion " that " this person must count the sweet and refreshing and many fertilizer of food also." become in " the recording proved recipe at all times " of book in 625 years Christian eras before, newly diabetes have been descended definite definition: " yearningly and drinking a lot of water, frequent micturition, no fat seemingly the sweet person of bran flakes all diabetes is also." yet along with development of times, the clinical characters of quenching one's thirst also has distinct characteristics of the times, quenching one's thirst of different times also ought to have different pathological characteristics.Ancient quenches one's thirst, and typical " three types of diabetes " symptom is arranged, and quench one's thirst now (diabetes) are mostly based on obesity, its body constitution is deficiency of both QI and YIN, stays in wet, heat, the stasis of blood, and it is inside and outside two evil in sick that pathogenesis is attributable to, function of five internal organs imbalance, spleen-QI transporting the essence to the whole body is had no right, precise and tiny must not positizing.

At present both at home and abroad adopt chemical synthetic drugs that diabetes are treated more, its short-term curative effects still can, but long-term effect is not good, easily has side effects and complication.TCM treatment of diabetes, it is dialectical to be based on macroscopic view, whole function and holistic health level with the conditioning patient are criterion, can not think to be exactly simple blood sugar lowering, make a general survey of the successive dynasties name side that quenches one's thirst, respectively at different syndromes or Yin-nourishing and Yang-supporting, or invigorating the spleen and replenishing QI, or clear away heart-fire and hold up spleen, or the lung moistening and production of body fluid promoting etc., consolidate the effect of radically reforming to reach.At present, the Chinese medicine of treatment diabetes is a lot, but the usefulness side that has is improper, and the curative effect that has is not obvious.If any prescription in used Radix Codonopsis, Radix Scutellariae etc. to have the blood glucose increasing function Chinese medicine, as disclosed Yidaokang powder and preparation method thereof among the Chinese patent literature CN 1437995; Used Rhizoma Zingiberis in the prescription that has, and Rhizoma Zingiberis property is hot, the deficiency of YIN has hot person's forbidding.

Summary of the invention

The technical problem to be solved in the present invention provides a kind of side's reasonable set, compatibility degree of having, and raw material sources are extensive, and medicinal essence is special, and all medicines share, and have supplementing QI and nourishing YIN, and promote the production of body fluid and moisturize, nourishing the stomach to promote the production of body fluid, the lung moistening nourishing kidney consolidates the Chinese medicine preparation of the effect of post-equalization.

For solving the problems of the technologies described above, the technical solution used in the present invention is:

A kind of medicine for the treatment of traditional Chinese medical science diabete comprises following former medicine by weight:

Monarch drug: Radix Ginseng 10～20, the Radix Astragali 20～40, Radix Trichosanthis 10～20;

Ministerial drug: Radix Rehmanniae 10～30, Rhizoma Coptidis 1～5, the Rhizoma Anemarrhenae 10～20, Rhizoma Dioscoreae 20～40, Fructus Corni 10～20;

Adjuvant drug: Gecko 20～40, Radix Salviae Miltiorrhizae 20～40, Bombyx Batryticatus 15～25.

The medicine of described treatment traditional Chinese medical science diabete also comprises ministerial drug: at least a in Colla Plastri Testudinis 10～20, the Colla cornus cervi 10～20; Also comprise messenger drug: at least a in Fructus Lycii 15～25, the Radix Achyranthis Bidentatae 15～25.

The medicine of described treatment traditional Chinese medical science diabete comprises following former medicine: Radix Ginseng 12～18, the Radix Astragali 25～35, Radix Trichosanthis 10～16, Radix Rehmanniae 15～25, Rhizoma Coptidis 2～4, the Rhizoma Anemarrhenae 10～15, Rhizoma Dioscoreae 25～35, Gecko 25～30, Fructus Corni 12～18, Radix Salviae Miltiorrhizae 25～30, Colla Plastri Testudinis 14～20, Colla cornus cervi 13～18, Bombyx Batryticatus 16～20, Fructus Lycii 15～20, Radix Achyranthis Bidentatae 15～20.

Said medicine is any one in powder, capsule, tablet, the pill.

The preparation method of described medicine is: be mixed in proportion after each former medicine is ground to form fine powder, and cross 80～200 mesh sieves, be powder, or powder compaction is become tablet or pill, or powder incapsulated make capsule.

A kind of medicine for the treatment of traditional Chinese medical science diabete, its component are the water extract that comprises the former medicine of following weight portion:

Monarch drug: Radix Ginseng 5～15 (emergency and severe disease 15～30), the Radix Astragali 10～30 (heavy dose of available), Radix Trichosanthis 10～20 to 30～120;

Ministerial drug: Radix Rehmanniae 10～30, Rhizoma Coptidis 2～8, the Rhizoma Anemarrhenae 6～12, Rhizoma Dioscoreae 10～30 (heavy dose of available), Fructus Corni 6～15 (first aid is taken off serious symptom admittedly and can be used to 20～30) to 60～250;

Adjuvant drug: Gecko 3～10, Radix Salviae Miltiorrhizae 5～15, Bombyx Batryticatus 3～10.

The former medicine for preparing described medicine also comprises ministerial drug: at least a in Colla Plastri Testudinis 5～15, the Colla cornus cervi 5～12; Also comprise messenger drug: at least a in Fructus Lycii 5～15, the Radix Achyranthis Bidentatae 6～18.

The former medicated bag of the preparation of described medicine is drawn together: Radix Ginseng 5～10, the Radix Astragali 10～20, Radix Trichosanthis 10～15, Radix Rehmanniae 10～20, Rhizoma Coptidis 2～5, the Rhizoma Anemarrhenae 6～9, Rhizoma Dioscoreae 10～20, Gecko 3～7, Fructus Corni 6～10, Radix Salviae Miltiorrhizae 5～10, Colla Plastri Testudinis 5～10, Colla cornus cervi 5～9, Bombyx Batryticatus 3～7, Fructus Lycii 5～10, Radix Achyranthis Bidentatae 6～10.

The former medicated bag of the preparation of described medicine is drawn together: Radix Ginseng 9～15, the Radix Astragali 20～30, Radix Trichosanthis 15～20, Radix Rehmanniae 20～30, Rhizoma Coptidis 4～8, the Rhizoma Anemarrhenae 8～12, Rhizoma Dioscoreae 20～30, Gecko 6～10, Fructus Corni 10～15, Radix Salviae Miltiorrhizae 10～15, Colla Plastri Testudinis 10～15, Colla cornus cervi 8～12, Bombyx Batryticatus 6～10, Fructus Lycii 10～15, Radix Achyranthis Bidentatae 10～18.

The preparation method of described medicine is: with total former medicine by medicine: the Capacity Ratio of water be 1: 1.2～5 soak at least 0.5 hour after, boiling the back decocted 0.5～1 hour, the elimination medicinal residues, again with the medicinal liquid cryoconcentration or be evaporated to 1/5th to 3/4ths of original volume, sterilization back fill.

The present invention has actively useful effect:

Function with cure mainly the inventor during the diagnosis and treatment primary disease of 40 over-carriages, grope meticulously, deeply study intensively, the secret recipe that ancestor's remittance is handed down from the older generations of the family, and in conjunction with modern medicine pharmacological research achievement, develop the present invention's medicine (being commonly called as " the hot Ji of profit ball in the last of the ten Heavenly stems ", capsule, diffusing, Tang Junke), treatment traditional Chinese medical science diabete (diabetes) and the various accompanied symptoms used produce effects excellent.

Take a broad view of its side, square reasonable set, compatibility degree of having, medicinal essence is special, and all medicines share, the nourishingization source, to control joint again, lung governing coordinative activities of viscera energy regulating fluid apssage is so be source on the water; The logical three warmers of a surname are with multiple gasification; Mediation Central Region is with multiple lifting; The Heibei provincial opera negative and positive, entire to open again; Have supplementing QI and nourishing YIN, promote the production of body fluid and moisturize, nourishing the stomach to promote the production of body fluid, the lung moistening nourishing kidney consolidates the effect of post-equalization.

2. to belong to scorching be main from the beginning of more for dialectical medication and composition principle assertive evidence, and the course of disease is than the elder, the then deficiency of YIN and scorching cross-reference, and it is main that disease then causes the deficiency of YIN for a long time.No matter the upper, middle and lower three types of diabetes all should be followed nourishing kidney-YIN, and promoting the production of body fluid to quench thirst consolidates the rule of treatment that post-equalization is attached most importance to.Scorching more very the time, the assistant heat clearing away, diabetes due to kidney-deficiency is for a long time sick, the suitable tonifying both YIN and YANG of deficiency of YIN affecting YANG person; The deficiency of YIN is scorching, causes blood stasis, then can help the product with blood circulation promoting and blood stasis dispelling.

The pharmacological effect of key component is summarized as follows in the side:

Radix Ginseng is the root of Araliaceae Radix Ginseng.Sweet in the mouth, temperature, be slightly cold, abnormal smells from the patient is all light, can rise and can fall, and the moon is arranged in the sun, and is nontoxic.Be the panacea of QI invigorating, living person's clever Seedling also.Radix Ginseng or ginsenoside have Accommodation to undesired blood glucose, can improve hypoglycemia, reduce hyperglycemia.Radix Ginseng extract, ginseng polysaccharide, ginseng polypeptide, Stem and leaf of Radix Ginseng polysaccharide, the non-saponin part of Radix Ginseng all have the effect of blood sugar lowering.This product sweet and slightly bitter taste and slightly warm in nature, the gas of kind tonifying five ZANG-organs, QI invigorating and hold concurrently can yin nourishing is kept and is not walked; The Radix Astragali is apt to away the flesh table, and QI invigorating is held concurrently can invigorating YANG, walks and does not keep.Two medicine mutual reinforcements between pairings, the effect with powerful invigorate vital energy and yang, and the two walks to keep, strongly invigorating primordial QI, promoting generation of vital essence and blood, negative and positive are taken into account, and are out and out, logical mend not have rush down.The deficient QI of the spleen and stomach person use with gas in inspiring, reach three warmers with accent, weak person is with QI invigorating Gu Wei for the deficiency of the lung, the insufficiency of heart-QI person of dispelling helps arteries and veins with reinforcing the heart.The not dry benefit strengthening spleen and lung of the sweet temperature of Radix Ginseng helps fortuneization, and semen deposition is little, and the cloth seminal fluid makes gas Wang Jinsheng, and to reach the effect that supplementing QI for promoting the production of body fluid quenches the thirst, it is thirsty to control Tianjin wound again, the card that deficiency-heat is quenched one's thirst.

The Radix Astragali is the root of leguminous plant Radix Astagali Astragalus membranaceus Bge.var.mongholicus (Bge.) Hsiao.Sweet in the mouth, tepor is returned spleen, lung meridian.Effect: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer granulation promoting, it is weak to be used for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.Contain astragaloside (I.II), daucosterol, cupreol, Palmic acid, sucrose, Radix Astragali glycosides and astragaloside in the Radix Astragali root.Astragalus polysaccharides is to have the effect that two-way conciliation joint is equipped with sugar.The Radix Astragali can promote RNA and albumen to synthesize; increase the content of cyclic nucleotide in mice and the tissue; reduce hyperglycemia, rising hypoglycemia, effects such as blood fat reducing; myocardial cell there is significant protective effect; Radix Astragali saponin energy arrhythmia, coronary artery dilator and peripheral blood vessel bring high blood pressure down, and improve anemia animal hemogram; reduce platelet adhesion rate, reduce thrombosis.Radix Astragali energy tonifying QI to produce body fluid is controlled deficiency of vital energy body fluid deficiency, and the card that interior-heat is quenched one's thirst, card see that the deficiency of YIN is this, and scorching for marking, impairment of body fluid consumes gas.Often with the product of nourishing YIN and clearing away heat such as Radix Ginseng, Radix Rehmanniae, the Rhizoma Anemarrhenae, Radix Trichosanthis mutually 5.

Radix Trichosanthis is the root of cucurbitaceous plant Fructus Trichosanthis.Nature and flavor are sweet, and little hardship is slightly cold, and attaches to the lung and stomach meridians.The tool heat clearing away is promoted the production of body fluid, and quenches the thirst, and moisturizes evacuation of pus, the effect of detumescence.Its property is sweet cold again, kindly can control yearningly, controls empty yearningly from tonic, and it is thirsty to control fire from the medicine of a cold nature, controls strongly fragrant yearningly from the gas medicine, controls excessive thirst from the blood medicine, is to control thirsty key medicine also.Contain saccharide compound in the radices trichosanthis, tangible immunoregulation effect is arranged, have significant antitumor and cytotoxic activity, polysaccharide mainly contains glucose, breast enlargement sugar, fructose, mannitol, xylose and a small amount of protein and forms; Still contain trace element manganese.Studies have shown that the blood sugar lowering effective ingredient of Radix Trichosanthis is a kind of glycoprotein, belongs to the phytohemagglutinin compounds, coagulate plain so be called Radix Trichosanthis.The in vitro tests proof has the lipotropism fat to decompose and promotes lipogenesis and ILA.This product that is not taken by pregnant women, anti-Aconitum carmichjaelii Debx..

Radix Rehmanniae is the tuber of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..The property sweet, bitter, cold, GUIXIN, liver, kidney channel.The tool clearing away heat and cooling blood, the effect of YIN nourishing and the production of body fluid promoting.Radix Rehmanniae contains cupreol, mannitol, catalpol, rehmanin, retinoid material.The sweet Han Zhirun of Radix Rehmanniae has the effect of clearing away heat and nourishing YIN, promoting the production of body fluid to quench thirst again, controls Tianjin wound again, and the card that interior-heat caused by deficiency of YIN is quenched one's thirst is used for the diabete of interior-heat caused by deficiency of YIN, thirsty polydipsia.

Rhizoma Coptidis is ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao, coptis omeiensis or Coptis teeta rhizome.Hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.This product is obeyed injuring spleen-stomach for a long time, and the Deficiency and coldness of spleen and stomach person avoids clothes.Bitter again dry impairment of body fluid, the also careful clothes of deficiency of YIN Tianjin the wounded.

The Rhizoma Anemarrhenae is liliaceous plant Rhizoma Anemarrhenae rhizome.Bitter but sweet flavor, cold in nature, return lung, stomach, kidney channel, both clearing up internal heat by using drugs of bitter in taste and cold in nature, sweet again cold yin nourishing, with clear and rich be its speciality, last can the lung heat clearing fire, the QI rising in reverse order of lung is fallen, be used for expectorant heat, xeropulmonary cough's card; In can cool gastric heat, the moon is deposited in pathogenic fire purging, it is bright to treat the heat stagnation sun, the card of hyperpyrexia agitation can be gone into kidney channel down, rushes down the fire mutually of having a surplus, and grows water lung benefiting stomach, is used for fever due to yin deficiency, quench one's thirst, the hectic fever due to YIN-deficiency consumptive fever, every interior-heat syndrome, no matter real deficiency syndrome are all used it.Go into stomach through can cool gastric heat, the moon is deposited in pathogenic fire purging, is the key medicine of hardship profit heat clearing away YIN nourishing.Rhizoma Anemarrhenae rhizome contains multiple steroidal saponin, and total saponins is about 6%, wherein isolates 1-timosaponin A-1 1, A2, A3, A4, B1, B2 etc.Still contain trace element such as zinc, manganese, copper, chromium.Its infusion extract can reduce the normal rabbit blood sugar level, and is more obvious to the effect of alloxan diabetes rabbit.

Rhizoma Dioscoreae is the tuber of Dioscoreaceae plant Rhizoma Dioscoreae.The property sweet, flat, return spleen, lung, kidney channel.Supplementing QI and nourishing YIN is arranged, spleen reinforcing lung kidney, the effect for the treatment of spontaneous emission and leukorrhagia.Modern pharmacological research proof Rhizoma Dioscoreae tuber contains dopamine, Rhizoma Dioscoreae alkali, and free amino acids etc. still contain glucoproteid (hydrolysis gets lysine, glutamic acid, serine etc.), contain lymphatic temperament (in mannan and phytic acid are arranged) again.The Rhizoma Dioscoreae sweet in the mouth is little puckery, is longer than tonifying the spleen and stomach, the lung benefiting kidney, and gas that can spleen reinforcing lung kidney can nourish the moon of spleen lung kidney again, is the key medicine of reinforcing both QI and YIN.With the Rhizoma Anemarrhenae two medicines pairings, mend combination clearly, both purte the white, clearing away stomach-heat, tonifying the lung the moon, nourishing stomach-YIN, kidney nourishing water bring out the best in each other again.This product yin nourishing can help wet, contains fullness in the epigastrium and abdomen and has stagnant person to use so wet.

Gecko is for Gekkonidae animal Gecko is removed all of internal organs.The property salty, flat, return lung, kidney channel.Body stink smell hero can rise and can fall.Invigorating the lung and the kidney is arranged, and supporing yang benefit is smart, and the effect of improving inspiration by invigorating kidney-QI Dingchuan cures mainly impotence due to deficiency of the kidney, sends essence, and frequent micturition is quenched one's thirst, deficiency of both the lung and kidney asthma, cough due to consumptive disease.Pharmacological research finds that this product has effects such as antiinflammatory is relievingd asthma, anti-stress, defying age, blood sugar lowering, growth promotion.Assistant this product is joined Radix Rehmanniae, the Radix Astragali is equal to usefulness, and all suffering from a deficiency of the kidney quenched one's thirst, the immoderate person that urinates, and the same usefulness of adding medicine to is to heat the merit that the kidney YIN nourishing is quenched the thirst.Points for attention: affection of exogenous wind-cold, breathe heavily and cough and hyperactivity of fire caused by deficiency of YIN person forbidding.

Fructus Corni is Cornaceae plant Fructus Corni pulp.Property acid, puckery, tepor is returned liver, kidney channel.The tool liver and kidney tonifying, arresting seminal emission reducing urination, the effect that consolidating channel for hemostasis, arresting sweating take off admittedly.This product acid Wen Zhirun, kind can liver and kidney tonifying, its warm in nature and not bath is mended and oiliness, can the kidney invigorating and essence nourishing, again can warming the kidney to activate YANG.Radix Rehmanniae, the Radix Trichosanthis of this product and YIN nourishing and the production of body fluid promoting are equal to usefulness, the available treatment diabetes.This product temperature compensation convergence, gate of vitality's heated have damp and hotly, and the puckery person of urine leaching should not use.

Radix Salviae Miltiorrhizae is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge.Bitter in the mouth, cold nature, GUIXIN, Liver Channel.Nourshing blood and promoting blood circulation is arranged, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the effect of the relieving restlessness that clears away heart-fire.Radix Salviae Miltiorrhizae contains fat-soluble two circle quinones and water solublity phenoloid, as TANSHINONES, dihydrotanshinone etc.This product merit is arrogated to oneself blood circulation promoting and blood stasis dispelling, and property is comparatively gentle, can promoting tissue regeneration by removing blood stasis and just do not hinder.

Colla Plastri Testudinis, the solid blob of viscose that becomes for the carapace infusion of Testudinidae animal Testudinis forms.Sweet in the mouth, salty, property are flat, return liver, kidney channel.Abnormal smells from the patient is dense, purely gloomily falls.Effect: nourishing YIN for decreasing fever, tonifying blood and arresting bleeding.Cure mainly the hepatic and renal YIN deficiency, the hectic fever hectic fever due to YIN-deficiency, night sweat, seminal emission, the waist knee flaccidity, palpitation due to deficiency of blood, spitting of blood is spitted blood, and has blood in stool metrorrhagia, leukorrhagia.Colla Plastri Testudinis contains ossein, keratin and several amino acids." the continuous flame of doctor's lamp " " controlled to superintend and direct and appointed all void, asthenia of essence and blood." " Zhang Shi doctor logical ": the Carapax et Plastrum Testudinis ERXIANJIAO is controlled Kidney-Yin deficiency of kidney-YIN again, can not nourish battalion and defend, gradually to weak or deficiency-heat contact; spontaneous sweating, or mental derangement, blood are not returned former; or deficient impairment of YIN, or loses to drench and can't help, or the deficiency of vital energy swoons; or dim eyesight tinnitus; or dry mouth dry tongue, or waist soreness, normal and Radix Rehmanniae, RHIIZOMA DIOSCOREAE frOm Henan of China, Fructus Lycii, Fructus Corni, Radix Cyathulae; Colla Plastri Testudinis, Colla cornus cervi compatibility.Stomach has cold-damp to prohibit clothes this product, " evil Radix Adenophorae (Radix Glehniae) ".

Colla cornus cervi is for the angle of animal in deer family Cervus nippon Temminck and Cervus elaphus linnaeus decocts the piece of frying in shallow oil that forms.Its property of medicine bitter in the mouth, salty, warm in nature, return liver, kidney channel.The greasy property of matter and, it is few to fall many liters.Effect: mend lean blood, antiabortive hemostasis.Cure mainly deficiency of both the liver and kidney, asthenia of essence and blood, weakness with emaciation is thin, dizziness and tinnitus, soreness of the waist and knees, the sexual impotence spermatorrhea, bleeding not during menses is spitted blood, epistaxis, spitting of blood, hematuria, traumatic injury, carbuncle of yin nature skin infection.This product composition is similar to Cornu Cervi, mainly contains colloid, calcium phosphate, calcium carbonate etc.

Bombyx Batryticatus is the ossified dry Scorpio of larva infection muscardine of Bombycidae insecticide bombyx mori.Nature and flavor are salty, hot, flat, return liver, lung meridian.Tool endogenous wind stopping relieving convulsion, wind-expelling pain-stopping, the effect of dissipating phlegm and resolving masses.Contain hormone hydroxy ecdysterone and a kind of pigment-3-hydroxyl cynruin in the Bombyx Batryticatus body.Contain oxalic acid, ammonium, protein and fat in the white lead of Bombyx Batryticatus body surface.The Bombyx Batryticatus powder has blood sugar decreasing effect preferably.

Fructus Lycii is the mature fruit of matrimony vine of solanaceae plant or lycium barbarum.Sweet in the mouth, flat is returned liver, kidney channel.The tool nourishing the liver and kidney, beneficial intensive culture blood, the removing nebula that makes eye bright, the function of nourishing the lung to arrest cough.Lycium barbarum extracts has remarkable and persistent hypoglycemic activity to rat, and carbohydrate tolerance raises, and effective ingredient is thought guanidine derivatives and flavonoid.This product can be controlled the interior-heat consumptive fever hectic fever due to YIN-deficiency of quenching one's thirst, epistaxis, and property is flat and not hot, and energy of moisturizing system fire arranged, the promoting the production of body fluid to quench thirst by the moon of nourishing the liver and kidney, thirsty with the interior-heat impairment of body fluid.Control diabetes involving the kidney, disease is seen the sliding number of urine, and xerostomia is vexed, xerosis cutis, and the lower limb knee joint disappears carefully, gradually to unable person.This product sweet in the mouth matter profit, kind nourishing kidney-yin, the kidney tonifying essence is the principal agent for nourishing YIN again, the deficiency of YIN that can invigorating the liver and kidney, can make eye bright by beneficial intensive culture liver again, then control poor vision, interior external oculopathy eye, tinnitus is forgetful, early whitening of beard and hair, the nocturia frequency of suffering from a deficiency of the kidney is returned through going into Liver and kidney, then can complementary energy support, so for the principal agent of nourishing YIN also.

Radix Achyranthis Bidentatae is the root of amaranthaceous plant cattle rattan.The property hardship, acid, flat, return the Liver and kidney warp.The tool promoting blood circulation to restore menstrual flow, ignite (blood) is descending, invigorating the liver and kidney, bone and muscle strengthening, the effect of relieving stranguria by diuresis.Radix Achyranthis Bidentatae contains various trace elements such as three circle saponin, steroid Lou chemical compound, glucuronic acid and zinc, manganese.Radix Achyranthis Bidentatae can bring high blood pressure down, and accelerates blood flow rate, the main and histamine's release of its blood pressure lowering mechanism, and central nerve inhibition and peripheral blood vessel expansion are relevant.Radix Achyranthis Bidentatae can lower blood viscosity, quickens clotting time, and dosage is big more, and blood viscosity reduces obvious more.The Radix Achyranthis Bidentatae decoct can also improve liver function, reduces serum cholesterol, and ecdysterone can make the hyperglycemia due to glucagon, AIS, the alloxan reduce.

Radix Ginseng, the Radix Astragali, Radix Trichosanthis three medicines phase 5 are to be monarch drug, supplementing QI and nourishing YIN is all arranged, promoting the production of body fluid to quench thirst, clearing heat and moistening lung, Radix Astragali tonifying QI to produce body fluid in the side, close the Radix Ginseng strongly invigorating primordial QI, again can promoting the production of body fluid to quench thirst, the supplementing QI for promoting the production of body fluid lung moistening, and nourishing YIN void is consolidated it, Radix Trichosanthis YIN nourishing clearing away lung-heat can nourish body fluid again, to control scorching mark.

Rhizoma Dioscoreae in the side, Fructus Corni, the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Rehmanniae five kinds of Chinese medicine 5 are to be ministerial drug mutually, and Rhizoma Dioscoreae matches with the Rhizoma Anemarrhenae two medicines, mends combination clearly, both purte the white, clearing away stomach-heat, and tonifying the lung the moon, nourishing stomach-YIN, kidney nourishing water bring out the best in each other again.The monarch and his subjects assist mutually, and not only the power of YIN nourishing strengthening the spleen brings out the best in each other, and have the effect of nourishing the liver spleen reinforcing concurrently.

Radix Salviae Miltiorrhizae, Colla Plastri Testudinis, Colla cornus cervi, Bombyx Batryticatus, Gecko are adjuvant drug.The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling nourishes blood, and the pairing Radix Astragali is mended strengthening spleen and lung vigour, and two medicines share QI invigorating and invigorate blood circulation and usefulness, and then the prosperous blood of gas is capable, and the blood circulation of qi promoting is also prosperous, plays benefiting QI for activating blood circulation altogether, the merit of weeding out the old and bring forth the new; Radix Salviae Miltiorrhizae is joined Bombyx Batryticatus energy expelling wind to relieve convulsion, dissipating phlegm and resolving masses and energy heat clearing away, and two medicines share, and the expectorant stasis of blood is also controlled, the hypertension of controlling phlegm and blood stasis again and causing, hyperlipidemia, coronary heart disease, diabetes etc., Bombyx Batryticatus can go into blood system search turbid, the vanishing sputum and dispelling knot collateral dredging, refrigerant dispeling the wind, secretly moving to liver-wind, it is very suitable that turbid pathogen is stopped up Sheng person; Colla Plastri Testudinis, Colla cornus cervi two medicines share, monoyin and monoyang, and tonifying both YIN and YANG, the logical arteries and veins of superintending and directing of being transferred to is so the big tonifying kidney-yin kidney yang of energy is treated void and held up win also.Last four flavor adjuvant drugs are associated with, have nourish blood, invigorate blood circulation, nourishing the liver and kidney, waking up the patient from unconsciousness by clearing away phlegm, endogenous wind stopping collateral dredging, card seeing and disappears card with the passing of time, essence and blood both consumed, positive wind-transformation is moving, takes advantage of key to steal network, the stiff tongue speech is stuttering, limbs are slow vertically not to be received; Or all scorching misfortune impairment of body fluid blood, positive wind-transformation is moving, and extremity are walked on the side, and are sick as acupuncture, brothers' toe numbness, light play at night in daytime, red tongue uncoated tongue surface like a mirror, pulse condition stringy and rolling pulse person.

Fructus Lycii, Radix Achyranthis Bidentatae are messenger drug, and the two mutually 5 equal invigorating the liver and kidney is a Fructus Lycii sweet in the mouth matter profit, kind nourishing kidney-yin, and the kidney tonifying essence is the principal agent of nourishing YIN, and the Radix Achyranthis Bidentatae liver and kidney tonifying, and strengthening the tendons and bones is held a concurrent post expelling wind and removing dampness, and it is descending that property is apt to, again can promoting blood circulation to disperse blood clots and relieves pain, be longer than promoting blood circulation to restore menstrual flow.The Radix Achyranthis Bidentatae invigorating the liver and kidney, it is descending to draw heat again, unit loses void so can be used for down, or the type of hyperactivity of fire caused by deficiency of YIN diabete.

Monarch drug must be indispensable among the top, minister, helps, makes three medicines then can take the circumstances into consideration to carry out certain adjustment configuration (increase, replace or delete according to the state of an illness or card shape progress) according to clinical dialectical situation.

3. the disease diagnosis is formulated with reference to " the clinical research guideline of new Chinese medicine treatment diabetes " with criterion of therapeutical effect

Produce effects: fasting glucose FPG＜7.2mmol/L (130mg/dl), 2 hours after the meal blood glucose PPG＜8.3mmol/L (150mg/dl), twenty-four-hour urine sugar quantitatively＜10.0g; Or blood glucose, twenty-four-hour urine sugar quantitatively descends more than 30%, and clinical symptoms disappears substantially;

Effectively: FPG＜8.3mmol/L (150mg/dl), PPG＜10/0mmol/L (180mg/dl), twenty-four-hour urine sugar quantitatively＜25.0g; Or blood glucose, twenty-four-hour urine sugar quantitatively descends more than 10%, and clinical symptoms is clearly better;

Invalid: FPG＞10.0mmol/L, PPG＞11.1mmol/L does not reach above-mentioned standard, and clinical symptoms does not have obvious improvement.

This prescription therapeutic traditional Chinese medical science diabetes produces effects excellent: the inventor accepts diabetes patient 3000 many cases in more than 100 county of 19 provinces, cities and autonomous regions in the whole nation for medical treatment altogether from 40 over-carriages of practising medicine, and wherein men and women patient's ratio is 7: 3; Wherein more than 2000 of between twenty and fifty people between 20～40 years old accounts for 60.2%; Middle-aged and elderly people is 300 between 45～65, accounts for 10.6%; Other are 29.2% years old.

According to statistics, produce effects 2523 examples among the routine patient account for 84.1% surplus in the of 3000, and effective 456 examples account for 15.2%, and invalid 21 examples account for 0.7%, total effective rate 99.3%.

The specific embodiment

1 one kinds of medicine pills for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 15kg, Radix Astragali 30kg, Radix Trichosanthis 15kg, Radix Rehmanniae kg, Rhizoma Coptidis 3kg, Rhizoma Anemarrhenae 12kg, Rhizoma Dioscoreae powder 30kg, Gecko 30kg, Fructus Corni 15kg, Radix Salviae Miltiorrhizae 30kg, Colla Plastri Testudinis 15kg, Colla cornus cervi 15kg, Bombyx Batryticatus 18kg, Fructus Lycii 18kg, Radix Achyranthis Bidentatae 18kg, (but after being arranged in the side, the former medicine lyophilizing of cement pulverizes after above-mentioned each former medicine ground to form fine powder, as Fructus Corni wherein, Fructus Lycii etc., Colla Plastri Testudinis, Colla cornus cervi then can suitably cure the back and pulverize, down together), mixing, and mistake 100 mesh sieves, add suitable quantity of water and make watered pill, every ball 6～9g is preserved in dry back, clothes were 2 times on 1st, each 1 ball warm water delivery service.

2 one kinds of medicine pills for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 10kg, Radix Astragali 20kg, Radix Trichosanthis 12kg, Radix Rehmanniae 12kg, Rhizoma Coptidis 2, Rhizoma Anemarrhenae 6kg, RHIIZOMA DIOSCOREAE frOm Henan of China 20kg, Gecko 20kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 20kg, Colla Plastri Testudinis 10kg, Colla cornus cervi 10kg, Bombyx Batryticatus 15kg, Fructus Lycii 15kg, Radix Achyranthis Bidentatae 15kg, Radix Notoginseng 10kg, Rhizoma Chuanxiong 10kg, after above-mentioned each former medicine ground to form fine powder, cross 120 mesh sieves, add Mel 40～45kg behind the mixing, making pellets by mixing medical powder with honey, every ball 6g, clothes were 2 times on 1st, each 1～2 ball, warm water delivery service.

3 one kinds of Chinese medicine preparation for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 20kg, Radix Astragali 12kg, Radix Trichosanthis 20kg, Rhizoma Anemarrhenae 10kg, Rhizoma Coptidis 6kg, Radix Rehmanniae 15kg, Rhizoma Dioscoreae 30kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 12kg, Colla cornus cervi 6kg, Colla Plastri Testudinis 12kg, Bombyx Batryticatus 15kg, Gecko 20kg, Fructus Lycii 18kg, Radix Achyranthis Bidentatae 18kg, preparation method and instructions of taking are with embodiment 1.

4 one kinds of Chinese powder medicines for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 10kg, Radix Astragali 20kg, Radix Trichosanthis 10kg, Radix Rehmanniae 10kg, Rhizoma Coptidis 1kg, Rhizoma Anemarrhenae 10kg, Rhizoma Dioscoreae 20kg, Gecko 20kg, Fructus Corni 10kg, Radix Salviae Miltiorrhizae 20kg, Colla Plastri Testudinis 10kg, Colla cornus cervi 10kg, Bombyx Batryticatus 15kg, Fructus Lycii 15kg, Radix Achyranthis Bidentatae 15kg, above-mentioned each former medicine is ground to form fine powder, cross mixing behind 150 mesh sieves, be powder, clothes were 2 times on 1st, each 6～9g, warm water delivery service.

5 one kinds of Chinese medicinal capsules for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 20kg, Radix Astragali 40kg, Radix Trichosanthis 20kg, Radix Rehmanniae 30kg, Rhizoma Coptidis 5kg, Rhizoma Anemarrhenae 20kg, Rhizoma Dioscoreae 40kg, Gecko 40kg, Fructus Corni 20kg, Radix Salviae Miltiorrhizae 40kg, Colla Plastri Testudinis 20kg, Colla cornus cervi 20kg, Bombyx Batryticatus 25kg, Fructus Lycii 25kg, Radix Achyranthis Bidentatae 25kg, above-mentioned each former medicine is ground to form fine powder, cross mixing behind 160 mesh sieves, pack 0 into ^#Capsule is adorned 1～2g for every, and clothes were 2 times on 1st, and each 3～6, warm water delivery service.

6 one kinds of Chinese medicinal tablets for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 15kg, Radix Astragali 30kg, Radix Trichosanthis 15kg, Radix Rehmanniae 20kg, Rhizoma Coptidis 3kg, Rhizoma Anemarrhenae 15kg, Rhizoma Dioscoreae 30kg, Gecko 30kg, Fructus Corni 15kg, Radix Salviae Miltiorrhizae 30kg, Colla Plastri Testudinis 15kg, Colla cornus cervi 15kg, Bombyx Batryticatus 20kg, Fructus Lycii 20kg, Radix Achyranthis Bidentatae 20kg, above-mentioned each former medicine is ground to form fine powder, cross mixing behind 80 mesh sieves, be pressed into tablet, every 2～3g, clothes were 2 times on 1st, and each 2～3, warm water delivery service.

7 one kinds of Chinese medicinal tablets for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 11kg, Radix Astragali 40kg, Radix Trichosanthis 20kg, Radix Rehmanniae 10kg, Rhizoma Coptidis 2kg, Rhizoma Anemarrhenae 20kg, Rhizoma Dioscoreae 40kg, Gecko 22kg, Fructus Corni 20kg, Radix Salviae Miltiorrhizae 20kg, Colla Plastri Testudinis 20kg, Colla cornus cervi 10kg, Bombyx Batryticatus 15kg, preparation method and instructions of taking are with embodiment 5.

8 one kinds of Chinese medicinal tablets for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 11kg, Radix Astragali 40kg, Radix Trichosanthis 20kg, Radix Rehmanniae 10kg, Rhizoma Coptidis 2kg, Rhizoma Anemarrhenae 20kg, Rhizoma Dioscoreae 40kg, Gecko 22kg, Fructus Corni 20kg, Radix Salviae Miltiorrhizae 20kg, Colla Plastri Testudinis 20kg, Colla cornus cervi 10kg, Bombyx Batryticatus 15kg, Fructus Lycii 25kg, Radix Achyranthis Bidentatae 15kg, Radix Notoginseng 8kg, preparation method and instructions of taking are with embodiment 5.

9 one kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 12kg, Radix Astragali 15kg, Radix Trichosanthis 20kg, Rhizoma Anemarrhenae 10kg, Rhizoma Coptidis 6kg, Radix Rehmanniae 15kg, Rhizoma Dioscoreae 20kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 12kg, Colla Plastri Testudinis 12kg, Colla cornus cervi 6kg, Bombyx Batryticatus 10kg, Gecko 8kg, Fructus Lycii 12kg, Radix Achyranthis Bidentatae 15kg, with above-mentioned former medicine by medicine: the Capacity Ratio of water is after soaking 1 hour at 1: 3, boil back slow fire boiling 0.5 hour, the elimination medicinal residues, medicinal liquid is evaporated to 1/4th of original volume, the fill of sterilization back oral solutions, obey twice every day, each 60～75ml.

10 1 kinds of extract oral liquid formulations for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 12kg, each 12kg of the Radix Astragali, Radix Trichosanthis 20kg, Rhizoma Anemarrhenae 10kg, Rhizoma Coptidis 6kg, Rhizoma Dioscoreae 12kg, Fructus Corni 15kg, Radix Rehmanniae 15kg, Radix Salviae Miltiorrhizae 12kg, Colla Plastri Testudinis 12kg, Colla cornus cervi 6kg, Bombyx Batryticatus 10kg, Gecko 10kg, Fructus Lycii 12kg, Radix Achyranthis Bidentatae 10kg, with above-mentioned former medicine by medicine: the Capacity Ratio of water is after soaking 1 hour at 1: 3, boil back slow fire boiling 0.5 hour, the elimination medicinal residues, with 1/5th of the extremely original volume of medicinal liquid cryoconcentration, the fill of sterilization back oral solutions, obey twice every day, each 50～60ml.

11 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 12kg, Radix Astragali 12kg, Radix Trichosanthis 20kg, Rhizoma Anemarrhenae 10kg, Rhizoma Coptidis 6kg, Radix Rehmanniae 15kg, Rhizoma Dioscoreae 15kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 12kg, Colla cornus cervi 6kg, Colla Plastri Testudinis 12kg, Bombyx Batryticatus 10kg, Gecko 10kg, Fructus Lycii 10kg, Radix Achyranthis Bidentatae 10kg, with above-mentioned former medicine by medicine: the Capacity Ratio of water is after soaking 0.5 hour at 1: 4, boil back slow fire boiling 1 hour, the elimination medicinal residues, with 1/5th of the extremely original volume of medicinal liquid cryoconcentration, the fill of sterilization back oral solutions, obey twice every day, each 50～60ml.

12 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 14kg, Radix Astragali 12kg, Radix Trichosanthis 20kg, Rhizoma Anemarrhenae 10kg, Rhizoma Coptidis 6kg, Radix Rehmanniae 15kg, Rhizoma Dioscoreae 30kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 12kg, Colla cornus cervi 6kg, Colla Plastri Testudinis 12kg, Bombyx Batryticatus 9kg, Gecko 10kg, Fructus Lycii 15kg, Radix Achyranthis Bidentatae 16kg, preparation method and instructions of taking are with embodiment 11.

13 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 10kg, Radix Astragali 20kg, Radix Trichosanthis 12kg, Radix Rehmanniae 12kg, Rhizoma Coptidis 2, Rhizoma Anemarrhenae 6kg, RHIIZOMA DIOSCOREAE frOm Henan of China 20kg, Gecko 3kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 20kg, Colla Plastri Testudinis 10kg, Colla cornus cervi 10kg, Bombyx Batryticatus 12kg, Fructus Lycii 12kg, Radix Achyranthis Bidentatae 15kg, preparation method and instructions of taking are with embodiment 9.

14 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 14kg, Radix Astragali 12kg, Radix Trichosanthis 30kg, Rhizoma Anemarrhenae 30kg, SHENGHUANG connect 6kg, Radix Rehmanniae 30kg, Rhizoma Dioscoreae 30kg, Fructus Corni 12kg, Radix Salviae Miltiorrhizae 12kg, Colla cornus cervi 6kg, Colla Plastri Testudinis 12kg, Bombyx Batryticatus 18kg, Gecko 10kg, Fructus Lycii 15kg, Radix Achyranthis Bidentatae 16kg, and preparation method and instructions of taking are with embodiment 11.

15 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 5kg, Radix Astragali 10kg, Radix Trichosanthis 10kg, Radix Rehmanniae 10kg, Rhizoma Coptidis 2kg, Rhizoma Anemarrhenae 6kg, Rhizoma Dioscoreae 10kg, Gecko 3kg, Fructus Corni 6kg, Radix Salviae Miltiorrhizae 5kg, Colla Plastri Testudinis 5kg, Colla cornus cervi 5kg, Bombyx Batryticatus 3kg, Fructus Lycii 5kg, Radix Achyranthis Bidentatae 6kg, preparation method and instructions of taking are with embodiment 9.

16 1 kinds of Chinese medicine oral liquid for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 15kg, Radix Astragali 30kg, Radix Trichosanthis 20kg, Radix Rehmanniae 30kg, Rhizoma Coptidis 8kg, Rhizoma Anemarrhenae 12kg, Rhizoma Dioscoreae 30kg, Gecko 10kg, Fructus Corni 15kg, Radix Salviae Miltiorrhizae 15kg, Colla Plastri Testudinis 15kg, Colla cornus cervi 12kg, Bombyx Batryticatus 10kg, Fructus Lycii 15kg, Radix Achyranthis Bidentatae 15kg, preparation method and instructions of taking are with embodiment 10.

17 1 kinds of Chinese medicine oral liquid for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 5kg, Radix Astragali 15kg, Radix Trichosanthis 10kg, Radix Rehmanniae 15kg, Rhizoma Coptidis 2kg, Radix Angelicae Sinensis 10kg, Radix Salviae Miltiorrhizae 12kg, Radix Paeoniae Alba 10kg, Bombyx Batryticatus 9kg, Radix Achyranthis Bidentatae 15kg, Fructus Lycii 12kg, Pheretima 10kg, Ramulus Mori 10kg, Rhizoma Dioscoreae 12kg, preparation method and instructions of taking are with embodiment 10.

18 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 10kg, Radix Astragali 20kg, Radix Trichosanthis 15kg, Radix Rehmanniae 20kg, Rhizoma Coptidis 5kg, Rhizoma Anemarrhenae 9kg, Rhizoma Dioscoreae 20kg, Gecko 7kg, Fructus Corni 11kg, Radix Salviae Miltiorrhizae 10, Bombyx Batryticatus 6kg, with above-mentioned former medicine by medicine: the Capacity Ratio of water is after soaking 1 hour at 1: 4, boil back slow fire boiling 0.5 hour, the elimination medicinal residues, concentrating under reduced pressure medicinal liquid to its volume is 1/4th of an original volume, the fill of sterilization back oral agents, obey twice every day, each 50～80ml.

19 1 kinds of extract oral liquors for the treatment of traditional Chinese medical science diabete of embodiment, composition of raw materials is as follows:

Radix Ginseng 5kg, Radix Astragali 10kg, Radix Trichosanthis 20kg, Radix Rehmanniae 30kg, Rhizoma Coptidis 8kg, Rhizoma Anemarrhenae 6kg, Rhizoma Dioscoreae 10kg, Gecko 3kg, Fructus Corni 6kg, Radix Salviae Miltiorrhizae 5kg, Colla Plastri Testudinis 5kg, Colla cornus cervi 12kg, Bombyx Batryticatus 3kg, Fructus Lycii 5kg, Radix Achyranthis Bidentatae 18kg, preparation method and instructions of taking are with embodiment 11.

Enumerating some concrete cases is below illustrated:

Case 1 Luo, man, 55 years old, people from squad of week battalion of administrative village, oil mill, Huang gang township, Huangchuan County, Henan Province committee, first visit in January, 1993.The main suit: thirsty, polydipsia, polyuria is become thin year surplus in the of 20, increases the weight of 3 months.

Medical history: the patient since the seventies thirsty, polydipsia appears, symptom such as become thin, once repeatedly checked blood glucose, numerical value is all higher, Western medicine diagnose is diabetes.Medicines such as informal dress insoral, glyburide, the state of an illness never is effectively controlled.Afterwards, pain in the low back and legs occurs, the right side has a pain in the leg bitterly, difficulty in walking, and others arranges living needs.

Existing disease: the patient has often had a sleepless night since onset, shortness of breath and fatigue, and it is dried partially to defecate, chronic facies, spirit is not good enough, and body is thin partially, lustreless complexion, dimly pale tongue is a little less than the thready and stringy pulse.Fasting glucose 16.95 milli rubs/liter, glucose in urine qualitative (++ ++).

Tcm diagnosis: the concurrent severe and migratory arthralgia of quenching one's thirst.Method of treatment: nourishing kidney-YIN, inrigorating qi and promoting blood circulation collateral dredging.Take oral solutions described in the embodiment 11 (profit Xin Jigui consolidate post-equalization soup) every day twice, sub-service sooner or later, each 60～70ml.

Two examine: after taking medicine 7, symptoms such as patient's xerostomia, polydipsia, polyuria all have and alleviate, and outdoor activities are carried out in the material life of taking care of oneself, and come the outpatient service check alone, and lumbago and skelalgia is alleviated substantially, should keep former side.

Three examine: continue to take medicine day surplus in the of 30, patient's above-mentioned symptom disappears substantially, and life is taken care of oneself fully.Visit half a year, blood glucose is repeatedly all in normal range.Take medicine for a long time for convenient, change pill described in the clothes embodiment 1, obey 2～4 balls every day, take at twice, consolidate curative effect, after resume work.

Comment: this times patient polydipsia, polyphagia, polyuria, become thin, the sour skelalgia of lower limb is deficiency of kidney yin, influence store essential substances, moisten the precise and tiny minimizing of supporting the five internal organs, lung stomach body fluid loses empty, the heart-yin secretly consumes, yang deficiency is unable with the system yang-energy, and then yang-energy is restless and give birth to interior-heat, long-term in addition hyperactivity of YANG due to deficiency of YIN, form qi-deficiency kidney-deficiency gradually, can not reach extremity by cloth, so see row difficulty, pain in the low back and legs.Therefore, treatment is moistened Xin Jigui with nourishing kidney-YIN, in conjunction with the inrigorating qi and promoting blood circulation collateral dredging, the side consolidates post-equalization soup with profit Xin Jigui, with tonifying kidney and nourishing yin, Radix Ginseng, Radix Astragali strongly invigorating primordial QI, promoting the production of body fluid to quench thirst, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, collateral dredging analgesia, two glue are tonifying both YIN and YANG again, again can the kidney invigorating and essence nourishing blood, then strengthen the merit of bone and muscle strengthening, the Radix Ginseng improving inspiration by invigorating kidney-QI, the meaning of Gecko improving inspiration by invigorating kidney-QI and the life of depletion water has the merit of two tonifying the lung kidneys; Ginseng, clam match, and have kidney invigorating and YANG supporting, the power of benefiting essence-blood; The hot salty endogenous wind stopping relieving convulsion that reduces phlegm of being longer than of Bombyx Batryticatus, wind-expelling pain-stopping, the exogenous wind of both having dispelled puts out endogenous wind again; Radix Achyranthis Bidentatae, the strong muscle of Fructus Lycii the kidney invigorating.All medicines share, nourishing kidney-YIN, and supplementing QI for promoting the production of body fluid promotes the production of body fluid and moisturizes, and the deficiency of YIN must be grown, and body fluid deficiency is benefited, and the deficiency of vital energy must be mended, and is evident in efficacy.

Case 2 reeds, man, 39 years old, cadre, Lu Ying people from squad of the diligent village of hilllock township Lu Ying committee that oil of Huangchuan County, Henan, first visit on November 25 in 1987.Main suit: year surplus the thirst and drinking 10.

Medical history: thirsty and dry pharynx over surplus the patient 10 year, the excessive thirst polydipsia, every day the drinking a lot of water liter.Once remove how tame hospital therapy, every inspection no abnormality seen also never is interrupted treatment, and it is countless so to take medicine, and its effect is not good.The dreaminess of previously sleeping, chest distress and palpitation symptoms, dyspnea with rapid and short breath is breathed hard, poor appetite, the tired power of body, coolness of extremities, diarrhea, every day for several times, clear urine in large amounts.Lower limbs edema in recent years, premature ejaculation.

Existing disease: patient's thirsty and dry pharynx, the excessive thirst polydipsia is drunk water 2000～3000 milliliters every day, companion's chest distress and palpitation symptoms, dyspnea with rapid and short breath is breathed hard, and is indigestion and loss of appetite, the tired power of body, coolness of extremities, diarrhea, every day is for several times; clear urine in large amounts, the difference of sleeping dreaminess, lower limb is swollen; premature ejaculation, and red tongue has be full of cracks; the greasy in vain little Huang of tongue, and wiry and frequent pulse is right greater than a left side.Patient's body is fat big, abdominal distention, lower limbs edema, by depression do not rise, face is slightly floating, lip is red.

Tcm diagnosis: quench one's thirst; Card belongs to qiactivity of triple energizer mistake department, and drink is stopped the supple of gas or steam stagnant, the body fluid loss.

Method of treatment: clearing heat and expelling damp is earlier.Earlier with square medicine sanren decoction plus-minus: roud cardamon seed 5g, Semen Coicis 30g, Poria 20g, LIUYI SAN (decocting a drug wrapped) 18g, Herba Plantaginis 20g, Cortex Magnoliae Officinalis degree flower 9g, Herba Pogostemonis pendant GENGGE 6g, Rhizoma Acori Graminei 9g, Fructus Chaenomelis 12g, Radix Glycyrrhizae 6g, this is the potion dose, makes oral solutions, every day potion, each 250～300 milliliters, 2 times on the one, sub-service sooner or later.

Two examine: December 17 days, and the patient takes nearly 20 doses of top, and dyspnea with rapid and short breath is breathed hard, and edema disappears, and belt is gradually wide, loses weight 5 kilograms, and drinking-water reduces 1/3rd, yellow and thin fur.Method of treatment changes into nourshing Yin and drynsessmoistening prescription, and QI invigorating heat clearing away and usefulness are taken embodiment 10 described oral solutionses, obey twice every day, each 50～60ml.

Three examine: on January 7th, 1988, the patient took medicine again 14, thirstyly obviously alleviated, and amount of drinking water subtracts greatly, and it is preferable to sleep, and coolness of extremities has alleviation greatly, and premature ejaculation disappears substantially, and stool every day 1 time, just matter is soft, and wiry and frequent pulse subtracts, white and thin fur, the few Tianjin of little Huang.Still keep preceding method, kind to consolidate it.

Comment: it is not normal that this patient demonstrate,proves the genus qiactivity of triple energizer, fluid-retention stagnating in the interior, and drink is stopped the supple of gas or steam stagnant, with the passing of time wets and accumulates heat-transformation, and consumption of body fluid by heat wets and feels frustrated, then impairment of both QI and YIN, then excessive thirst taking fluids profusely; Be primary in damp and hotly, continue to become and lose in the moon.The method of treatment, it is damp and hot clearly in the ban, and Semen Armeniacae Amarum is declared sharp part of the body cavity above the diaphragm housing the heart and lungs lung qi in the first visit, the lid the lung is concerned with QI of the whole body, gasification is then wet also changes roud cardamon seed removing dampness by means of aromatics, promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Semen Coicis, the sweet light property of Poria are put down then spleen invigorating eliminating dampness by diuresis; Sweet cold light the oozing of Herba Plantaginis, LIUYI SAN strengthened the power of sharp temperature heat clearing away; Flos Magnoliae Officinalis, leaves of pulse plants pendant obstruct, Rhizoma Acori Graminei is amusing removing dampness, regulate the flow of vital energy and have one's ideas straightened out; The Fructus Chaenomelis removing dampness to restore normal function of the stomach, digesting and appetizing; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription.All medicines share, and three core mutually 5 are oozed among the Xuan Shangchang and descended, and make the three warmers mechanism of qi unobstructed, and temper is healthy and vigorous, and diseases caused by retention of fluid must remove.Two when examining, and patient's damp syndrome is separated, and the interior-heat body fluid deficiency does not eliminate, and changes nourishing kidney-YIN then, and the agent of moisturizing of promoting the production of body fluid is thrown it, promptly reaches its purpose with the side of the present invention.In damp and hot and deficiency of both QI and YIN interweave, treat the most thornyly, it is well arranged that this example is faced card, the balance deficiency and excess, and the side's of sending medication, apt, so the bone joints-most important juncture of hitting is can be with a flat side severe and lingering illness obstinate disease.

Case 3 Zhangs, the man, 51 years old, Shangcheng County, Henan Province Yan Gang village people was in December in 1999 first visit on the 16th.The main suit: polydipsia, polyuria, the moon of becoming thin is surplus.

Medical history: the patient is over nearly one month, do not have that obvious inducement is thirsty, a polydipsia, polyuria, and is heavy, but obviously becomes thin, accompany weak, cold perspiration.

Existing disease: thirsty, polydipsia, polyuria, appetite is as usual, loses weight 6 kilograms, and is weak obvious, cold perspiration.52 kilograms of existing body weight, dimly red tongue, tongue is white, and stringy pulse is slow.Glucose in urine (++ ++), blood glucose 16.2 millis rub/liter, cholesterol 7.49 millis rub/liter.

Tcm diagnosis: quench one's thirst, card belongs to QIYINLIANGXU.Method of treatment: take oral solutions described in the embodiment 11, every day 2 times, each 50～60ml; Keep on a diet simultaneously, take the photograph sugar and be no more than 250g every day, protein 100g, and fatty 50g eats vegetable when hungry.

Two examine: on January 13rd, 2000, and the thirsty improvement of patient, hypourocrinia, the staple food amount must be controlled, and sweating due to debility disappears, 0.56 kilogram of weight increase, muscle power is recovered to some extent, but the feel blurred vision, body of the tongue is light red, thin white fur of tongue, pulse condition stringy and thready pulse, blood glucose 13.3 milli rub/liter, glucose in urine (+++).The deficiency of vital energy takes a turn for the better, deficiency of YIN liver-yang hyperactivity.Intend high and level tone liver method, take the oral solutions described in the embodiment 12, every day 2 times, each 50～60 milliliters.

Three examine: February 28, all diseases of patient are taken a turn for the better, and look thing and recovered normally, glucose in urine (++), 58 kilograms of body weight, the body of the tongue inflammation is red, white and thin fur, deep-thready pulse is slow.Liver-yang is flat, QIYINLIANGXU.The side still keeps the place ahead, preceding method.

The four diagnostic methods: there was expectorant on April 7 in patient's pharynx, and the steam sense is arranged, surplus no discomfort, and muscle power is multiple normal, glucose in urine (+), body of the tongue is light red, white and thin fur, stringy pulse.The deficiency of YIN has heat, increases the weight of Radix Rehmanniae, Radix Trichosanthis, the Rhizoma Anemarrhenae, Bombyx Batryticatus consumption in the side, i.e. preparation described in the embodiment 14, and removing heat-phlegm closes the same usefulness of all medicines, nourishing YIN and clearing away heat, YIN nourishing and the production of body fluid promoting.

Five examine: May 19, last month 24, patient's glucose in urine was turned out cloudy, and blood glucose is normal, and body weight is stabilized in 58 kilograms, and muscle power is normal, is engaged in operate as normal.Continue and obey the pill described in the embodiment 3, to consolidate curative effect, an order 2 times, each 1 ball warm water delivery service.

Comment: this routine patient belongs to 2 type glycosurias, adds the may command that takes traditional Chinese medicine by diet control.

Case 4 chapters, woman, 39 years old, Zhang village village, Bao Xin town, Xi County, Henan Province two peasants of squad that entrust, JIUYUE in 2000 first visit on the 27th.The main suit: drink is not known hungry full, outbreak repeatedly in nearly 2 years.

Medical history: patient husband accident is met accident deadly before 15 years, suffers huge direct stimulation, after this works with all one's might every day about 12 hours.Patient's prominent sense hunger in coming home from work on the way is hard to bear before 2 years, and having enough and just go out in the dining shop, soon starves again, returns and eat, and so repeatedly several times, money is most in the capsule, and the household comes to pay off meal expense back and suddenly sends to hospital, examines to be diabetes, leaves hospital behind infusion treatment.After this adhere to western medicine, but still outbreak repeatedly, inferior surplus in the of 10 before extremely going to a doctor, symptom increases the weight of gradually, each all hospitalization.At any time carry confection in the patient bag usually, in order to the need of outbreak, body weight increases to present 85 kilograms by original 50 kilograms, takes traditional Chinese medicine between once.

Existing disease: patient's hunger sensation is obvious, the polyphagia insatiable hunger, and thirsty polydipsia, weak, it is unreal sleep, even had palpitation, the every day 5～6 times of defecating, shapeless, menstrual blood volume is few, and color is light, and there is the tooth mark on the enlarged tongue limit, white and thin fur, thready pulse decimal.Patient's obesity.

Tcm diagnosis: quench one's thirst; Card belongs to taste imbalance, deficiency of both the heart and spleen.Method of treatment: invigorating the spleen and regulating the stomach, nourishing blood to tranquillize the mind sedate.The side medicine: the present invention moisten Xin Jigui consolidate the post-equalization Tonga subtract Radix Ginseng 15g, Radix Astragali 12g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Rhizoma dioscoreae (parched) 15g, Radix Trichosanthis 15g, Radix Salviae Miltiorrhizae 20g, Rhizoma Anemarrhenae 12g, Rhizoma Coptidis 10g, Radix Polygalae 12g, this is a dosage, is decocted in water for oral dose 1 dose of every day, each 300 milliliters, sub-service sooner or later on the one.

Two examine: October 8, patient's hunger sensation is still the same, still has feeling of repletion after the food, weakly slightly subtracts.Surplus disease is the same substantially, enlarged tongue, and there is indentation on the limit, and root of the tongue tongue is thick slightly, rolling pulse.Still keep the place ahead, method such as preceding method continue and obey 7 doses.

Three examine: October 15, the patient is in good mood, and shows the smile, and feeling of repletion is arranged after the feed.Feed prolongs blanking time, and full sense is the same, only be shaped, menstruation extremely, there is indentation on the enlarged tongue limit, rolling pulse.Former side adds the Rhizoma Anemarrhenae, and each 9g of Fructus Corni continues and obeys 14 doses, and instructions about how to take medicine are the same.

The four diagnostic methods: all symptoms of patient all have alleviation, and the oral solutions described in the embodiment 16 is taken in the plus-minus conditioning on the former side basis, and taking medicine sky surplus in the of 60 altogether and heal in front and back, resumes work.

Comment: this patient comes from feelings will and hinders, and adds overwork again, falls sick from overwork, dialectical genus taste imbalance, deficiency of both the heart and spleen.Method of treatment is worked as with invigorating the spleen and regulating the stomach, the tranquilizing by nourishing the heart sedate.This routine patient knows hungry insatiable hunger, and the gastric heat polyphagia that deficiency of the spleen and heat of the stomach causes is become thoroughly decomposed too, but insufficiency of the spleenly causes becoming thoroughly decomposed and the turbid descending functional disorder of stomach, and the functional disorder of stomach, rather than not enough, but too.This is the key point of primary disease treatment.

Case 5 Zhangs, man, 58 years old, Xincai County, the Henan Province retired cadre of cultural bureau, February 12 nineteen eighty-three.The main suit: thirsty weak, the companion's lower limb pain of becoming thin is surplus half a year.

Medical history: the patient has a dizzy spell once because of thirst and drinking July nineteen eighty-two, and the urine of urinating increases, lose weight, and the lower limb twinge, the sugar that has urine examined (+++), blood glucose 9.99 millis rubs/liter, live certain hospitalize with diabetes, sciatica.While in hospital orally-taken blood sugar reducing spirit, intramuscular injection VB12, and carry out physical therapy and massage, the sugar (±) that has urine examined after 1 month, blood glucose 7.77 millis rub/liter, right acroesthesia does not subtract.Nineteen eighty-two, December was checked at certain hospital's Neurology Department, and got rid of the lower limb twinge that the cerebral tumor causes, doctor trained in Western medicine is examined to diabetes merge polyneuritis, and school advises it to leave hospital with treatment by Chinese herbs, changes the inventor then over to and locates diagnosis and treatment.

Existing disease: patient's lower limb persistence such as the twinge of electric shock sample, can not touch clothing, then support clothing at nightfall with waddy, have a pain in case touch.Respectively there are 20 cm x, 5 cm section pain in the two lower limb outside more so, and companion's dizziness and blurred vision is moving then increase the weight of, and very then desire is fallen forward, bitter taste in the mouth and dry throat, and urine is still transferred, and it is soft to defecate, and go every days 2, and body of the tongue is light red, white and thin fur, stringy and thready pulse.

Tcm diagnosis: quench one's thirst arthralgia aggravated by cold; Card belongs to the hepatic and renal YIN deficiency, the resistance of venation numbness.Method of treatment: nourishing the liver and kidney, dispel the wind promoting blood circulation to remove obstruction in the collateral.Side's medicine: return medicine Dihuang Wan plus-minus (Radix Rehmanniae 10g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 12g, Ramulus Mori 15g, Radix Achyranthis Bidentatae 10g, Rhizoma Dioscoreae 10g, Radix Astragali 15g, Poria 10g, Ramulus Cinnamomi 6g, Pheretima 10g, Radix Angelicae Pubescentis 6g, Fructus Lycii 10g, Radix Glycyrrhizae Preparata 5g, this is 1 dose), be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, each 200～300 milliliters.

Two examine: 32 doses of clothes are advanced in the top, and all illness of patient all subtract, and acroesthesia ten goes seven or eight, and sleep is supported clothing without waddy, and walking is sane, and the sound of receiving is just transferred, and continue with adjusting and reinforcing liver and kidney, and the nourishing blood and promoting blood circulation assistant is a rule of treatment with the collateral dredging.Take oral liquid described in the embodiment 17, sub-service sooner or later, each 50～60 milliliters.Defence's medical treatment two weeks, dizziness and blurred vision, two lower limb pains are removed, check blood glucose 5.83 millis to rub/liter, weight increase is left hospital and is continued conditioning.

Comment: the card of quenching one's thirst, intense heat of YANG MING pents up dryness-transformation, the bright body fluid that disappears, and then undermine Liver and kidney.Liver governing tendons, kidney governing bones, deficiency of the liver and kindey, muscles and bones lose to be supported, Rong Ze pain not, thus the side recover Tonga and subtract with consolidating with the 'Guishao Dihuang ball, to consolidate post-equalization, nourishing the kidney and liver, treating both the principal and secondary aspects of a disease.The Radix Rehmanniae, Radix Angelicae Sinensis, Radix Paeoniae, Fructus Lycii, Radix Achyranthis Bidentatae, Radix Astragali nourishing kidney tonifying liver in the side, strong muscles and bones; Radix Salviae Miltiorrhizae, Ramulus Mori, Radix Angelicae Pubescentis, Pheretima, Bombyx Batryticatus are with the expelling wind and activating blood circulation collateral dredging.The merging arthralgia aggravated by cold of quenching one's thirst, real be obstinate disease, only keeps pathogenesis, the specimen smelting of holding concurrently, though to recover, the evil receipts merit of removing of eutopic reduction.

Case 6 Huangs, woman, 58 years old, the peasant of Xu Fu village, Guan Jin township, Xincai County, Henan committee, JIUYUE in 1998 first visit on the 18th.The main suit: suffered from diabetes 16 years, two lower limb pains are sent out cold, right sufficient middle toe blackout, blue 8 months.

Medical history: the patient found diabetes before 16 years, the treatment of oral glyburide spirit once.In December, 1997 copper acidosis is lived certain hospital and is used insulinize instead, fasting glucose be controlled at 7.6～9.6 the milli rub/liter, post-prandial glycemia 8～11.4 the milli rub/liter.1989 from the beginning of whole body pain, extremity more so, pain is as the sample that lancinates, si dol urg is difficult to stand, so that roll about, and send out cold with lower limb, right sufficient middle toe blackout is blue, inspection turns out to be diabetes and merges peripheral neuropathy, retinopathy I-II level, diabetic foot (confirmation of artery of lower extremity doppler ultrasound), (B ultrasonic shows left kidney diffuse lesion to diabetic nephropathy, urine protein+), hypertension.Rare when doing during stool, sleep night can, the while in hospital once annotates with 654-2 vein point, body is painful slightly to take a favorable turn, but the alleviation yet of the cool pain of lower limb, so treat.

Existing disease: patient's both hands refer to numb, the cool fiber crops of two lower limb, and acupuncture sample pain is difficult to stand, and increases the weight of during walking, and the right side is sufficient more very, right sufficient middle toe redness, nail root place blackout, brothers have the ankle socks sense.Fasting glucose 8 milli rubs/liter, 2 hours after the meal blood glucose 10 millis rub/liter, rare when doing during stool, day 1～2 row, xerostomia is thirsty, spiritlessness and weakness, sleep poor night, and dark tongue quality has ecchymosis, and corpulent tongue is big, and there is indentation on the limit, the few Tianjin of white and thin fur, thready and stringy pulse CHI-pulse being weak.Two hypodermis temperature are low, the purplish red swelling of right sufficient middle toe, nail root place blackout, about 1 centimetre of diameter, two ankle joint hyporeflexias, lower limb do not have edema, cardiopulmonary (one), 18.7/ kPa of blood pressure (140/170 millimetres of mercury), serum creatinine, blood urea nitrogen are in normal range, and triacylglycerol and very low density lipoprotein (VLDL) increase, kidney figure position element, the kidney dynamic chek all has left renal function poor, urine protein (+), twenty-four-hour urine albumen 0.2 gram.

Western medicine diagnose: type 2 diabetes mellitus complication with diabetes foot (dry gangrene), peripheral neuropathy, retinopathy and diabetic nephropathy, hypertension, hyperlipidemia.

Tcm diagnosis: diabetes.Syndrome belongs to deficiency in both YIN and YANG, phlegm and blood stasis, venation block.Method of treatment: the present invention moisten Xin Jigui consolidate the post-equalization Tonga subtract: Radix Ginseng 12g, Radix Astragali 20g, Radix Trichosanthis 10g, Radix Rehmanniae 12g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Colla cornus cervi 12g, Radix Salviae Miltiorrhizae 15g, Bombyx Batryticatus 12g, Radix Achyranthis Bidentatae 18g, Rhizoma Chuanxiong 12g, Hirudo 9g, Caulis Spatholobi 20g, Ramulus Cinnamomi 9g, this is 1 dosage, is decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, each 250～300 milliliters.

Two examine: October 8, after 20 doses, the cold of patient's lower limb, fiber crops, pain all alleviated above obeying, and right toe swelling is disappeared, and still has black, and big loose stool is thin, and go every day 1～2, and mouth is not thirsty, and dark tongue quality has ecchymosis, the tongue body hypertrophy, and there is indentation on the limit, stringy pulse.Method of treatment is still kept the place ahead, consolidates post-equalization, warming and recuperating the kidney-YANG, replenishing QI to invigorate the spleen, activating blood circulation to dissipate blood stasis and dredge the collateral.

Three examine: October 28, patient's toes are cool painful to be alleviated, and not bitterly, but finger, toes are still felt fiber crops and expand that big loose stool is thin during walking, and every day 1～2, row was mouthful thirsty, and dark tongue quality has ecchymosis, corpulent tongue, indented tongue margin, stringy pulse.Method of treatment adds Radix Angelicae Sinensis 15g on the basis up, Semen Persicae 12g, and Fructus Corni 12g is decocted in water for oral dose, 1 dose of every day, 2 times on the 1st, sub-service sooner or later, each 200～300 milliliters.

The four diagnostic methods: November 16, patient's lower limb are sent out cold and are obviously alleviated, pain relief, right sufficient middle toe black and aubergine swelling are obviously gone down, night xerostomia, bitter taste, lower limbs edema is not obvious, and blood pressure is steady, big dry stool, the tip of the tongue is dark red, and there is indentation on the limit, the few Tianjin of white and thin fur, stringy and thready pulse.Fasting glucose 8.1 milli rubs/liter.The side uses: Radix Ginseng 15g, Radix Astragali 30g, Radix Rehmanniae 15g, Radix Trichosanthis 15g, Fructus Corni 15g, Radix Achyranthis Bidentatae 15g, Semen Persicae 10g, Flos Carthami 12g, Rhizoma Chuanxiong 10g, the system breast does not have 9g, Ramulus Cinnamomi 6g, Colla cornus cervi 12g, this is 1 dosage, makes oral solutions, 1 dose of every day, 2 times on the 1st, sub-service sooner or later, each 200～300 milliliters.

Five examine: December 6 days, and the patient obeys 20 doses of tops, the not cool pain of lower limb toes, the red and swollen blackout of right crus of diaphragm second toe is not obvious, and the sense of ankle socks glove alleviates, but still has feeling of numbness, and blood pressure is steady, red tip of the tongue, the few Tianjin of white and thin fur, thready and stringy pulse.Fasting glucose 7.3～7.6 milli rubs/liter, 2 hours after the meal blood glucose 10.1 millis rub/liter, renal function is normal, and hemodynamics is normal substantially, twenty-four-hour urine albumen 0.01g.Control with replenishing QI to invigorate the spleen, nourishing kidney consolidates, and promoting blood circulation to remove obstruction in the collateral is taken oral solutions described in the embodiment 13, every day twice, sub-service sooner or later, each 250 milliliters.

Six examine: December 26 days, patient's lower limb are not cool bitterly, and toes black disappears, and the sense of glove ankle socks is not obvious, and blood pressure is steady, and the tip of the tongue is little red, white and thin fur, stringy and thready pulse.Fasting glucose 6.3 milli rubs/liter, post-prandial glycemia 7.4～9.4 millis rub/liter, urine protein (-), two artery of lower extremity doppler ultrasounds show that two artery of lower extremity blood flows are unobstructed, frequency spectrum is: phase wave, empty window exists, and is bifilar, the dorsal artery of foot internal diameter is normal.For convenient its curative effect of consolidating, take pill described in the embodiment 2, every day 2 times, each 2 ball warm water delivery services.Adhered to taking medicine nearly so far 4 years, lower limb are cold type of pain more not, and blackout, redness appear in toes again, also do not have sense of hands ankle socks and feeling of numbness again; Renal function is normal, urine protein (-), and lower limbs edema, blood pressure is steady.

Comment: diabetes merge the multiple complications poor prognosis.This case patient has related to big and small vessel, and peripheral nerve is clinical heavier, has belonged to the internal organs deficiency in both YIN and YANG, so that phlegm and blood stasis, and venation block is a simulataneous insufficiency and excessive, the card of deficiency in origin and excess in superficiality.Treat first warming and recuperating the kidney-YANG, replenishing QI to invigorate the spleen, the phlegm reduction of blood circulation promoting collateral dredging, the card of the deficiency of kidney yin of waiting takes a turn for the better to some extent, and then based on spleen benefiting and strengthen kidney, blood circulation promoting and blood stasis dispelling is then prosecuted to the end, could obtain the comparatively good result of clinical and various inspection.To reach solid first the foundation of acquired constitution, to dispel with the eutopic reduction heresy, severe and lingering illness or habit must be removed, and is the strong post-equalization of body.

Claims

1. medicine for the treatment of traditional Chinese medical science diabete comprises the following former medicine in weight portion:

2. the medicine of treatment traditional Chinese medical science diabete according to claim 1 is characterized in that, the medicine of described treatment traditional Chinese medical science diabete also comprises ministerial drug: at least a in Colla Plastri Testudinis 10～20, the Colla cornus cervi 10～20; Also comprise messenger drug: at least a in Fructus Lycii 15～25, the Radix Achyranthis Bidentatae 15～25.

3. the medicine of treatment traditional Chinese medical science diabete according to claim 2 is characterized in that, the medicine of described treatment traditional Chinese medical science diabete comprises following former medicine:

Radix Ginseng 12～18, the Radix Astragali 25～35, Radix Trichosanthis 10～16, Radix Rehmanniae 15～25, Rhizoma Coptidis 2～4, the Rhizoma Anemarrhenae 10～15, Rhizoma Dioscoreae 25～35, Gecko 25～30, Fructus Corni 12～18, Radix Salviae Miltiorrhizae 25～30, Colla Plastri Testudinis 14～20, Colla cornus cervi 13～18, Bombyx Batryticatus 16～20, Fructus Lycii 15～20, Radix Achyranthis Bidentatae 15～20.

4. according to the medicine of any described treatment traditional Chinese medical science of the claim diabete of claim 1～3, it is characterized in that described medicine is any one in powder, capsule, tablet, the pill.

5. the medicine of treatment traditional Chinese medical science diabete according to claim 4, it is characterized in that, the preparation method of described medicine is: be mixed in proportion after each former medicine is ground to form fine powder, and mistake 80～200 mesh sieves, be powder, or powder compaction become tablet or pill, or powder incapsulated make capsule.

6. medicine for the treatment of traditional Chinese medical science diabete, its component comprises the water extract of the former medicine of following weight portion:

Monarch drug: Radix Ginseng 5～15, the Radix Astragali 10～30, Radix Trichosanthis 10～20;

Ministerial drug: Radix Rehmanniae 10～30, Rhizoma Coptidis 2～8, the Rhizoma Anemarrhenae 6～12, Rhizoma Dioscoreae 10～30, Fructus Corni 6～15;

7. the medicine of treatment traditional Chinese medical science diabete according to claim 6 is characterized in that, the former medicine for preparing described medicine also comprises ministerial drug: at least a in Colla Plastri Testudinis 5～15, the Colla cornus cervi 5～12; Also comprise messenger drug: at least a in Fructus Lycii 5～15, the Radix Achyranthis Bidentatae 6～18.

8. the medicine of treatment traditional Chinese medical science diabete according to claim 7 is characterized in that, the former medicated bag for preparing described medicine is drawn together:

Radix Ginseng 5～10, the Radix Astragali 10～20, Radix Trichosanthis 10～15, Radix Rehmanniae 10～20, Rhizoma Coptidis 2～5, the Rhizoma Anemarrhenae 6～9, Rhizoma Dioscoreae 10～20, Gecko 3～7, Fructus Corni 6～10, Radix Salviae Miltiorrhizae 5～10, Colla Plastri Testudinis 5～10, Colla cornus cervi 5～9, Bombyx Batryticatus 3～7, Fructus Lycii 5～10, Radix Achyranthis Bidentatae 6～10.

9. the medicine of treatment traditional Chinese medical science diabete according to claim 7 is characterized in that, the former medicated bag of the preparation of described medicine is drawn together:

Radix Ginseng 9～15, the Radix Astragali 20～30, Radix Trichosanthis 15～20, Radix Rehmanniae 20～30, Rhizoma Coptidis 4～8, the Rhizoma Anemarrhenae 8～12, Rhizoma Dioscoreae 20～30, Gecko 6～10, Fructus Corni 10～15, Radix Salviae Miltiorrhizae 10～15, Colla Plastri Testudinis 10～15, Colla cornus cervi 8～12, Bombyx Batryticatus 6～10, Fructus Lycii 10～15, Radix Achyranthis Bidentatae 10～18.

10. according to the medicine of any described treatment traditional Chinese medical science of the claim diabete of claim 6～8, it is characterized in that, the preparation method of described medicine is: with total former medicine by medicine: the Capacity Ratio of water be 1: 1.2～5 soak at least 0.5 hour after, boil back slow fire boiling 0.5～1 hour, the elimination medicinal residues, again with the medicinal liquid cryoconcentration or be evaporated to 1/5th to 3/4ths of original volume, sterilization back fill.