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CN100571606C - A kind of microrobot and external guidance system thereof - Google Patents

A kind of microrobot and external guidance system thereof Download PDF

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CN100571606C
CN100571606C CNB2006101654959A CN200610165495A CN100571606C CN 100571606 C CN100571606 C CN 100571606C CN B2006101654959 A CNB2006101654959 A CN B2006101654959A CN 200610165495 A CN200610165495 A CN 200610165495A CN 100571606 C CN100571606 C CN 100571606C
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宋涛
李晓南
王铮
王明
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/70Manipulators specially adapted for use in surgery
    • A61B34/73Manipulators for magnetic surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147Holding or positioning arrangements
    • A61B1/00158Holding or positioning arrangements using magnetic field
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging

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Abstract

A kind of microrobot and external guidance system thereof, fuselage [1a] internal placement has permanent magnet block [1b], micromotor [1f], radio frequency receiver [1d], minicell [1e], afterbody rotating mechanism [1h] forms a fixed connection by the swingle that stretches out in the through hole of fuselage [1a] rear end with afterbody [1i], and swingle and fuselage [1a] adopt the sealing of high resiliency diaphragm seal.The external alignment control system of microrobot, treat search coverage by imaging subsystems [6] and carry out continuous sweep, the gained raw image data is admitted to computer control subsystem [7] and carries out image reconstruction, magnetic orientation subsystem [5] carries out magnetic orientation to the inner permanent magnet block [1b] of microrobot [1], the gained original position-information is admitted to computer control subsystem [5] and carries out the position reconstruction, computer control subsystem [5] produces the guiding control information and also is passed to magnetic steering subsystem [4], and magnetic steering subsystem [4] is to microrobot [1] control of leading.

Description

一种微型机器人及其体外导向系统 A kind of micro-robot and its external guidance system

技术领域 technical field

本发明涉及仿生微型机器人技术领域,特别涉及微型机器人及其体外导向系统。The invention relates to the technical field of bionic micro-robots, in particular to a micro-robot and an in vitro guidance system thereof.

背景技术 Background technique

随着机器人技术和微电子机械系统的发展,微型机器人成为国内外研究的热点,特别是进入人体的无线内窥镜、血管机器人以及面向工业设备细小管路探测用的微型机器人,其发展和应用尤其受到重视。由于工作环境的特殊,这类微型机器人不可能是普通机器人的简单微小化,特别是在驱动方式上会与普通机器人有很大的不同。目前,微型机器人的驱动方式大致可以分为两类:一类是利用机器人本体执行机构进行驱动;另一类是借助外场进行驱动,主要是利用一些功能材料对外加物理场的响应特性制成微执行器,通过外场激励实现无线驱动。With the development of robot technology and micro-electro-mechanical systems, micro-robots have become a research hotspot at home and abroad, especially the development and application of wireless endoscopes that enter the human body, vascular robots, and micro-robots for the detection of small pipelines in industrial equipment. are especially valued. Due to the special working environment, this type of micro-robot cannot be a simple miniaturization of ordinary robots, especially in the way of driving will be very different from ordinary robots. At present, the driving methods of micro-robots can be roughly divided into two categories: one is driven by the actuator of the robot body; The actuator realizes wireless drive through external field excitation.

对于本体执行机构驱动方式来说,大多采用仿生驱动方式,如D.Reynaerts等模仿尺蠖制成了消化道检查机器人模型、S.Hirose设计出仿蛇机器人、浙江大学周银生等提出了仿蜗牛和仿蝌蚪机器人、中国科学院合肥智能机械研究所梅涛等提出了仿壁虎爬行机器人以及上海交通大学颜国正等研制了微型六足仿生机器人等。由于工作环境对机器人的体积有严格的要求,因此,目前这些仿生微型机器人的可控自由度较少,一般来说没有专门的姿态控制,而是靠管路或接触面的自然约束来实现,因此对接触面会有一定的损伤,这对于医疗机器人来说是不利的,在一些曲率较大的地方甚至可能造成堵塞。外场驱动方式的研究也比较活跃,如T.Yasuda等研制了由超声场驱动的微型蚂蚁、T.Fukuda等用巨磁致伸缩材料制成了由交变磁场驱动的管路微型机器人、K.Ishyama等用缠绕有螺旋金属线的永磁材料制成了由旋转磁场驱动的微型机器人、中国科学院合肥智能机械研究所梅涛等研究了外磁场驱动的胶囊内窥镜机器人以及中国科学院电工研究所王秋良等研制了均匀梯度磁场驱动永磁磁块的磁导航外科手术模型系统等。这些机器人本体不需要电动机,也不需要内部提供能量,因此尺寸可以做得很小,有的已经做到直径小于1.5mm,但是缺少姿态控制,以及灵活性欠佳。在很多应用场合下,将两种驱动方式结合起来可能是一种更好的方案,自然界中趋磁细菌的运动形式就是采用类似的方式。For the driving mode of body actuators, most of them adopt bionic driving mode. For example, D.Reynaerts imitated the inchworm to make a robot model for digestive tract inspection, S.Hirose designed a snake-like robot, and Zhou Yinsheng of Zhejiang University proposed a snail-like and bionic robot. Tadpole robot, Mei Tao, Hefei Institute of Intelligent Machinery, Chinese Academy of Sciences, etc. proposed a gecko-like crawling robot, and Yan Guozheng, Shanghai Jiaotong University, etc. developed a miniature hexapod bionic robot. Because the working environment has strict requirements on the size of the robot, these bionic micro-robots currently have less controllable degrees of freedom. Generally speaking, there is no special attitude control, but it is realized by the natural constraints of pipelines or contact surfaces. Therefore, there will be certain damage to the contact surface, which is unfavorable for medical robots, and may even cause blockage in some places with large curvature. The research on external field driving methods is also relatively active. For example, T. Yasuda et al. have developed miniature ants driven by ultrasonic field, T. Fukuda et al. have made pipeline micro-robots driven by alternating magnetic field with giant magnetostrictive materials, K. Ishyama et al. made a micro-robot driven by a rotating magnetic field with a permanent magnet material wound with a helical metal wire. Mei Tao et al. studied a capsule endoscopic robot driven by an external magnetic field and the Institute of Electrical Engineering, Chinese Academy of Sciences. Wang Qiuliang and others have developed a magnetic navigation surgery model system with a permanent magnetic block driven by a uniform gradient magnetic field. The body of these robots does not require motors, nor does it require internal energy supply, so the size can be made very small, and some have achieved a diameter of less than 1.5mm, but they lack attitude control and poor flexibility. In many applications, it may be a better solution to combine the two driving methods. The movement form of magnetotactic bacteria in nature uses a similar method.

趋磁细菌是一类具有趋磁性行为的细菌,体内含有排列成链状的单磁畴颗粒(即磁小体),端部生有由鞭毛马达驱动的螺旋状鞭毛。在自然环境中,地磁场作用于磁小体链产生磁转矩,迫使趋磁细菌沿地磁场取向。细菌体内的趋化传感器是负责感应环境变化的受体复合体蛋白--甲基趋化蛋白,可以启动鞭毛马达使鞭毛逆时针旋转,驱动菌体沿地磁场方向直线泳动,由此探寻适合其生长的微好氧环境。这样,趋磁细菌利用地磁场将三维空间的探寻任务简化为一维空间的探寻任务,已有研究表明,这种方式大大提高其探寻速度以及探寻效率。Magnetotactic bacteria are a type of bacteria with magnetotropic behavior. They contain single magnetic domain particles (magnetosomes) arranged in chains in their bodies, and spiral flagella driven by flagellar motors grow at the ends. In the natural environment, the geomagnetic field acts on the magnetosome chains to generate magnetic torque, forcing magnetotactic bacteria to orient along the geomagnetic field. The chemotaxis sensor in bacteria is a receptor complex protein responsible for sensing environmental changes—methyl chemoattractant protein, which can activate the flagellar motor to rotate the flagella counterclockwise and drive the bacteria to swim in a straight line along the direction of the geomagnetic field. The microaerobic environment in which it grows. In this way, magnetotactic bacteria use the geomagnetic field to simplify the search task in three-dimensional space to one-dimensional space search task. Studies have shown that this method greatly improves their search speed and search efficiency.

美国专利5337732、5662587、5906591“仿蛇或尺蠖内窥镜机器人”,中国专利01126965.0“六足仿生微型机器人”,均采用基于本体执行机构的驱动方式。上述美国专利“仿蛇或尺蠖内窥镜机器人”,本体执行机构为机器人体内多段相互连接的关节,包括牵引关节和激励关节,通过对每个关节的动作进行有序控制,使机器人做类似于蛇或尺蠖的移动。上述中国专利“六足仿生微型机器人”主要包括机架、微电动机、蜗轮蜗杆装置、皮带传动装置、四杆机构,以及前足、中足和后足,其连接方式为:机架内部设有微电动机、蜗轮蜗杆装置、皮带传动装置,机架外部设有四杆机构与前足、中足和后足各两条,微电动机与蜗轮蜗杆装置连接,通过皮带又与皮带传动装置连接,皮带传动装置的轴分别与四杆机构连接,并将动力分别传给四杆机构,四杆机构分别与前足、中足和后足连接,并带动六足步行。本发明中,机器人体内含有微型电池、射频接收器、微电动机、尾部旋转机构与尾部,由计算机通过射频发射器控制微电动机的动作,带动尾部旋转机构工作,使机器人向前或向后移动。U.S. patents 5,337,732, 5,662,587, and 5,906,591 "snake or inchworm-like endoscopic robot" and Chinese patent 01126965.0 "hexapod bionic micro-robot" all adopt the drive method based on the body actuator. The above-mentioned U.S. patent "snake-like or inchworm endoscopic robot", the main body actuator is a multi-section interconnected joints in the robot body, including traction joints and excitation joints. By orderly controlling the movements of each joint, the robot can do things similar to The movement of snakes or inchworms. The above-mentioned Chinese patent "hexapod bionic micro-robot" mainly includes a frame, a micro-motor, a worm gear device, a belt drive, a four-bar mechanism, and a forefoot, a middle foot, and a rear foot. Electric motor, worm gear device, belt transmission device, four-bar mechanism and two forefoot, middle foot and rear foot are arranged outside the frame, the micro motor is connected with the worm gear device, and connected with the belt transmission device through the belt, the belt transmission device The axes of the four-bar mechanism are respectively connected with the four-bar mechanism, and the power is transmitted to the four-bar mechanism respectively, and the four-bar mechanism is respectively connected with the front foot, the middle foot and the rear foot, and drives the hexapod to walk. In the present invention, the robot body contains a micro battery, a radio frequency receiver, a micro motor, a tail rotation mechanism and a tail, and the computer controls the movement of the micro motor through a radio frequency transmitter to drive the tail rotation mechanism to make the robot move forward or backward.

另一类专利涉及外场驱动微型机器人技术,例如中国专利200510040887.8“体内探测外磁场驱动装置及方法”与中国专利200410009485.7、200410009528.1。上述专利所涉及的外磁场驱动技术均是利用组合线圈系统构造空间中较为均匀的梯度磁场(由常导或超导线圈产生),通过调整加载电流的大小以及部分线圈相对于人体的运动共同控制梯度的大小与方向,该梯度磁场作用于磁性微型机器人的内置磁性体以获得期望的空间矢量力,进而实现期望的运动。本发明中,外部导向线圈产生均匀导向磁场,迫使磁性微型机器人的内置磁体沿导向磁场方向偏转,从整个移动过程来看,微型机器人趋于沿管路延伸的切线方向移动,驱动微型机器人移动的能量由微型机器人内部的微电动机等装置提供。Another type of patent involves external field-driven micro-robot technology, such as Chinese patent 200510040887.8 "In vivo detection of external magnetic field driving device and method" and Chinese patents 200410009485.7 and 200410009528.1. The external magnetic field driving technology involved in the above patents is to use the combined coil system to construct a relatively uniform gradient magnetic field (generated by normal or superconducting coils) in the space, and jointly control the magnitude of the loading current and the movement of some coils relative to the human body. The magnitude and direction of the gradient, the gradient magnetic field acts on the built-in magnetic body of the magnetic micro-robot to obtain the desired space vector force, and then realize the desired movement. In the present invention, the external guiding coil produces a uniform guiding magnetic field, forcing the built-in magnet of the magnetic micro-robot to deflect along the direction of the guiding magnetic field. From the perspective of the entire movement process, the micro-robot tends to move along the tangential direction of the pipeline extension, driving the micro-robot to move Energy is provided by devices such as micro-motors inside the micro-robot.

当前,医疗机器人技术日益得到重视,由于体内环境的特点,传统机器人很难发挥作用,因此各种仿生微型机器人应运而生,但目前仿生微型机器人在体积的微型化和运动的灵活性等方面还存在不足。At present, medical robot technology is getting more and more attention. Due to the characteristics of the internal environment, it is difficult for traditional robots to play a role. Therefore, various bionic micro-robots have emerged as the times require. It has a shortpart.

发明内容 Contents of the invention

本发明的目的是克服现有微型机器人驱动技术中存在的姿态控制与移动灵活性欠佳等缺点,借鉴趋磁细菌的运动方式,提出一种主动螺旋推进结合外磁场姿态控制的仿生微型机器人及其体外导向系统。在一定程度上,本发明解决了机器人体积微型化与运动灵活性之间的矛盾,可在体内诊疗和非磁性细小管路的探测中发挥重要作用。The purpose of the present invention is to overcome the disadvantages of poor attitude control and movement flexibility in the existing micro-robot drive technology, learn from the movement mode of magnetotactic bacteria, and propose a bionic micro-robot with active helical propulsion combined with external magnetic field attitude control. its in vitro guidance system. To a certain extent, the invention solves the contradiction between the miniaturization of the volume of the robot and the flexibility of movement, and can play an important role in in vivo diagnosis and treatment and detection of non-magnetic small pipelines.

1、本发明微型机器人功能及结构说明如下:1. The function and structure of the micro-robot of the present invention are described as follows:

本发明微型机器人在外部导向磁场及体内微电动机的驱动下,沿导向磁场方向偏转,并沿管路延伸的切线方向向给定目标前进,并能够在计算机控制下通过射频发射接收器调节微电动机,使机器人做正向、反向移动。Driven by the external guiding magnetic field and the internal micro-motor, the micro-robot of the present invention deflects along the direction of the guiding magnetic field, and advances to a given target along the tangential direction of the pipeline extension, and can adjust the micro-motor through the radio frequency transmitting receiver under the control of the computer , to make the robot move forward and backward.

微型机器人包括以下组成部分:机身、永磁磁块、微电动机、射频接收器、微型电池、尾部旋转机构以及尾部。The micro-robot includes the following components: fuselage, permanent magnet block, micro-motor, radio-frequency receiver, micro-battery, tail rotating mechanism and tail.

微型机器人的机壳制作成胶囊状,两端圆滑,中间无突起和沟槽,表面采用光滑的、具有一定韧性和柔性的医用材料包覆,以减少与管路内壁的摩擦。机身内部镂空,前端内周面上开有一用于固定永磁磁块的螺旋槽,底部开有一个轴向通孔,机身用左右对称的两块材料加工制成,安装时两者合二为一粘贴成一体。微电动机外形为长方体,布置在机身内。机器人尾部旋转机构用于驱动形状类似于趋磁细菌鞭毛的尾部,尾部由柔韧性较好医用材料制成,尾部与从机身通孔内伸出的旋转杆形成固定连接,采用高弹性密封膜将旋转杆与机身密封。射频接收器安装在机身的内周面上,微电动机与射频接收器均由装在机身内的微型电池供电。The casing of the micro-robot is made into a capsule shape, with smooth ends and no protrusions or grooves in the middle. The surface is covered with smooth, tough and flexible medical materials to reduce friction with the inner wall of the pipeline. The interior of the fuselage is hollowed out. There is a spiral groove on the inner peripheral surface of the front end for fixing the permanent magnet block, and an axial through hole is opened on the bottom. The fuselage is made of two symmetrical materials. Two for one paste into one. The shape of the micro-motor is a cuboid, arranged in the fuselage. The tail rotation mechanism of the robot is used to drive the tail with a shape similar to the flagella of magnetotactic bacteria. The tail is made of medical materials with good flexibility. The tail is fixedly connected with the rotating rod protruding from the through hole of the fuselage, and a high elastic sealing film is used. Seal the swivel rod to the body. The radio frequency receiver is installed on the inner peripheral surface of the fuselage, and both the micro motor and the radio frequency receiver are powered by a micro battery installed in the fuselage.

所述永磁磁块相当于趋磁细菌体内的磁小体链,具有磁矩,在外部导向磁场的作用下会产生磁转矩,趋向于导向磁场的方向。The permanent magnet block is equivalent to the magnetosome chain in the magnetotactic bacteria, and has a magnetic moment, which will generate a magnetic torque under the action of an external guiding magnetic field, tending to the direction of the guiding magnetic field.

当正向接通微电动机的电极时,微电动机驱动尾部旋转机构正向转动,进而带动柔性尾部周期性正向转动。反之,在操作者通过计算机的控制下,反向接通微电动机的电极时,旋转杆将带动尾部反向转动,环境液体对机器人产生向后的轴向推力,使机器人后退。When the electrodes of the micro-motor are turned on in the forward direction, the micro-motor drives the tail rotating mechanism to rotate forwardly, and then drives the flexible tail to rotate forwardly periodically. Conversely, when the operator reversely connects the electrodes of the micro-motor under the control of the computer, the rotating rod will drive the tail to rotate in the reverse direction, and the environmental liquid will generate a backward axial thrust on the robot, causing the robot to retreat.

本发明中,由计算机产生射频发射信号,由机器人体内的射频接收器接收,控制微电动机的转动方向和转速,再结合其他体外控制装置,实现对微型机器人移动的控制。In the present invention, the computer generates the radio frequency transmission signal, which is received by the radio frequency receiver in the robot body to control the rotation direction and speed of the micro motor, and then combined with other external control devices to realize the control of the movement of the micro robot.

2、本发明微型机器人体外导向系统包括磁定位子系统、成像子系统、磁导向子系统以及计算机控制子系统,其中计算机控制子系统提供人机交互界面,通过控制磁定位、成像与磁导向子系统实现对微型机器人移动的控制。计算机控制子系统作为中央控制台,通过数据总线和控制总线分别连接磁定位子系统、成像子系统与磁导向子系统,完成对其它子系统工作状态的控制并进行数据交换。各子系统功能及工作原理说明如下:2. The in vitro guidance system of the miniature robot of the present invention includes a magnetic positioning subsystem, an imaging subsystem, a magnetic guidance subsystem and a computer control subsystem, wherein the computer control subsystem provides a human-computer interaction interface, and controls the magnetic positioning, imaging and magnetic guidance subsystems. The system realizes the control of the movement of the micro-robot. As the central console, the computer control subsystem connects the magnetic positioning subsystem, the imaging subsystem and the magnetic guiding subsystem respectively through the data bus and the control bus to control the working status of other subsystems and exchange data. The functions and working principles of each subsystem are described as follows:

2.1磁定位子系统2.1 Magnetic positioning subsystem

在不考虑外扰磁场的情况下,本子系统的功能是测量出永磁磁块磁场空间分布的变化,并转化为电流信号提供给计算机,计算机通过求逆算法,计算出永磁磁块、即微型机器人的位置,可以实现连续位置测量。同时结合成像子系统分阶段提供的机器人与管路间的相对位置,使操作人员通过计算机实时获得机器人的相对位置。Without considering the external disturbance magnetic field, the function of this subsystem is to measure the change of the spatial distribution of the magnetic field of the permanent magnet block, and convert it into a current signal and provide it to the computer. The computer calculates the permanent magnet block through the inverse algorithm, namely The position of the micro-robot can achieve continuous position measurement. At the same time, combined with the relative position between the robot and the pipeline provided by the imaging subsystem in stages, the operator can obtain the relative position of the robot in real time through the computer.

本子系统主要由8个巨磁电阻(GMR)传感器构成,所述传感器分布于一虚拟的罩于被测管路外面的长方体的8个顶点上。根据磁阻效应,巨磁电阻的电阻率能够随着外磁场的变化而变化,则在给定电压下电阻中流过的电流会发生变化。根据该电流变化,计算机能够利用磁定位求逆算法求出永磁磁块的坐标。This subsystem is mainly composed of 8 giant magnetoresistance (GMR) sensors, and the sensors are distributed on the 8 vertices of a virtual cuboid covering the outside of the pipeline under test. According to the magnetoresistance effect, the resistivity of the giant magnetoresistance can change with the change of the external magnetic field, and the current flowing in the resistance will change at a given voltage. According to the current change, the computer can use the magnetic positioning inversion algorithm to obtain the coordinates of the permanent magnet block.

永磁磁块在其周围空间中激发的磁场具有特定的分布规律,因此可通过检测该磁场的变化确定永磁磁块的位置。当永磁磁块的尺寸远远小于检测点和永磁磁块间的距离时,永磁磁块可等效为磁偶极子,其空间磁场分布模型可以用下式表示:The magnetic field excited by the permanent magnet block in its surrounding space has a specific distribution law, so the position of the permanent magnet block can be determined by detecting the change of the magnetic field. When the size of the permanent magnet block is much smaller than the distance between the detection point and the permanent magnet block, the permanent magnet block can be equivalent to a magnetic dipole, and its spatial magnetic field distribution model can be expressed by the following formula:

中的磁导率,

Figure C20061016549500062
为磁偶极子的磁矩矢量,
Figure C20061016549500063
为磁偶极子到检测点的矢径。 The magnetic permeability in
Figure C20061016549500062
is the magnetic moment vector of the magnetic dipole,
Figure C20061016549500063
is the vector radius from the magnetic dipole to the detection point.

2.2成像子系统2.2 Imaging subsystem

本子系统采用成熟的X射线计算机断层成像技术对探测区域进行三维成像,考虑到管路可能做微小的随机运动,以及获得机器人位置信息的速度与成像速度相差较大,因此,本发明中成像子系统对管路与机器人进行周期性成像,每一幅图像被用于在相应的周期内辅助对机器人移动的导向。根据计算机断层成像原理,X射线源发出的X射线穿过受检体投射至检测器,X射线检测器收到与局部X射线衰减系数有关的投影数据并送入计算机,再由计算机通过图像重建算法重构关于受检体的图像,即管路与机器人的图像,可以得到管路的三维延伸方向与管路尺寸信息。This subsystem adopts mature X-ray computed tomography imaging technology to perform three-dimensional imaging of the detection area. Considering that the pipeline may make small random movements, and the speed of obtaining the position information of the robot is quite different from the imaging speed, therefore, the imaging sub-system in this invention The system periodically images the pipeline and the robot, and each image is used to aid in the guidance of the robot's movement during the corresponding period. According to the principle of computerized tomography, the X-rays emitted by the X-ray source pass through the subject and project to the detector. The X-ray detector receives the projection data related to the local X-ray attenuation coefficient and sends it to the computer, and then the computer reconstructs the image The algorithm reconstructs the image of the subject, that is, the image of the pipeline and the robot, and can obtain the three-dimensional extension direction and size information of the pipeline.

本子系统包括X射线源、X射线检测器圆周阵列、成像电源、移动床、接口电路以及显示器,其中,X射线检测器圆周阵列位于与移动床轴向垂直的平面内,X射线源在该平面内可做圆周扫描,成像电源用于给X射线源与X射线检测器圆周阵列供电,接口电路用于接收原始图像数据并进行滤波、格式转化等预处理,然后将其输入计算机控制子系统进行图像重建与合成,最后由显示器显示出来。This subsystem includes an X-ray source, a circular array of X-ray detectors, an imaging power supply, a moving bed, an interface circuit, and a display, wherein the circular array of X-ray detectors is located in a plane perpendicular to the axial direction of the moving bed, and the X-ray source is on the plane Circumferential scanning can be done inside, the imaging power supply is used to supply power to the X-ray source and the X-ray detector circular array, the interface circuit is used to receive the original image data and perform preprocessing such as filtering and format conversion, and then input it into the computer control subsystem for further processing The image is reconstructed and synthesized, and finally displayed on the monitor.

工作时,将受检体置于移动床上,该床可沿自身轴线方向平移,并能在扫描平面内进行微移动以使待成像部位位于成像区域内。X射线源发出的X射线经准直后成为一条很窄的射线束,X射线源在扫描平面内,以成像部位的几何中心为圆心做断层圆周扫描。本子系统采用光电二极管作为X射线检测器,将若干个光电二极管以圆周阵列的形式布置于扫描平面上,与扫描圆周同圆心,成像过程中该阵列位置不变。When working, the subject is placed on the moving bed, which can translate along its own axis and move slightly in the scanning plane so that the part to be imaged is located in the imaging area. The X-rays emitted by the X-ray source become a very narrow beam after being collimated. The X-ray source is in the scanning plane, and the geometric center of the imaging part is used as the center of the circle to scan the tomographic circle. This subsystem uses photodiodes as X-ray detectors, and several photodiodes are arranged on the scanning plane in the form of a circular array, concentric with the scanning circle, and the position of the array remains unchanged during the imaging process.

本子系统是在二维平面成像的基础上,通过对多个连续断层分别成像并合成,实现对管路与机器人进行三维成像,即需要先利用反投影重建算法得到二维图像。对某一个断层进行成像时,首先在移动床的驱动下将待成像断层移至成像区域,然后X射线源以恒定角速度作360°圆周扫描。扫描完一周以后,X射线源回到起始位置,等到下一个待扫描断层进入扫描平面后,再对下一个断层进行扫描。对指定部位扫描完毕后,计算机利用图像处理程序对原始图像数据进行处理并重建出每一幅断层图像,最后合成为一幅管路与机器人的三维图像。This subsystem is based on two-dimensional plane imaging, and realizes three-dimensional imaging of pipelines and robots by separately imaging and synthesizing multiple continuous slices, that is, it is necessary to use back projection reconstruction algorithm to obtain two-dimensional images. When imaging a slice, the slice to be imaged is first moved to the imaging area driven by the moving bed, and then the X-ray source performs a 360° circular scan at a constant angular velocity. After one week of scanning, the X-ray source returns to the initial position, and the next slice to be scanned is scanned after entering the scanning plane. After the specified parts are scanned, the computer uses image processing programs to process the original image data and reconstruct each tomographic image, and finally synthesize a three-dimensional image of the pipeline and the robot.

2.3磁导向子系统2.3 Magnetic Guidance Subsystem

在移动床的配合下,本子系统可在中心区域产生指向所需方向的均匀导向磁场,对永磁磁块实施偏转性导向控制,进而实现对微型机器人的姿态控制。导向磁场的方向由磁导向算法得到,并由接口电路将导向磁场信号传送至磁导向子系统电源。根据磁定位子系统测得的机器人的位置,以及成像子系统提供的管路与机器人间相对位置,操作者可以实时给出微型机器人的移动方向,由导向磁场作用于永磁磁块实现。利用磁导向算法,本子系统能够根据机器人的姿态生成沿所需方向的导向磁场。导向磁场由在三组亥姆霍兹线圈中通以可调直流电流得到,即由空间中方向两两正交的三个磁场叠加而成。这种方法操作简单,能有效地控制机器人的姿态,使其在管路中移动时较易克服空间狭小、转弯等一些障碍。With the cooperation of the moving bed, this subsystem can generate a uniform guiding magnetic field pointing to the desired direction in the central area, implement deflection guiding control on the permanent magnet block, and then realize the attitude control of the micro robot. The direction of the steering magnetic field is obtained by the magnetic steering algorithm, and the interface circuit sends the steering magnetic field signal to the magnetic steering subsystem power supply. According to the position of the robot measured by the magnetic positioning subsystem and the relative position between the pipeline and the robot provided by the imaging subsystem, the operator can give the moving direction of the micro robot in real time, which is realized by the guiding magnetic field acting on the permanent magnet block. Using the magnetic guidance algorithm, this subsystem can generate a guidance magnetic field along the desired direction according to the pose of the robot. The guiding magnetic field is obtained by passing an adjustable DC current through three sets of Helmholtz coils, that is, it is formed by superimposing three magnetic fields with two pairs of orthogonal directions in space. This method is simple to operate and can effectively control the attitude of the robot, making it easier to overcome some obstacles such as narrow space and turning when moving in the pipeline.

磁导向算法的流程包括:首先,建立统一坐标系,根据成像子系统生成的管路延伸图像建立一条机器人参考移动轨迹,可选取管路的中心延伸轴为参考轨迹;在图像的有效时间内,将机器人的移动轨迹用若干间断点连接而成的折线代替,所述间断点即为由磁定位子系统测得的机器人位置;确定导向磁场的方向时,当机器人的尺度相远远小于管路的长度时,可将机器人看成一质点,假设t=t0时刻机器人位于p0(x0,y0,z0),在磁定位子系统位置分辨率允许的范围内,经过时间Δt,Δt→0,微型机器人移动至p1(x1,y1,z1)点,再在参考移动轨迹上找到一点,该点为p1在参考移动轨迹上的正交投影,计算出在参考移动轨迹上该投影点处切线方向的方向导数,以及由p0点指向p1的方向导数,由程序计算出两个方向导数之差,该差值即为t=t0+Δt时刻所需的方向修正值;最后将该方向修正值转化为导向磁场的控制参数,即线圈中电流的修正值,计算机将此修正值由接口电路传送至磁导向子系统电源装置,最终产生所需的导向磁场。The process of the magnetic guidance algorithm includes: firstly, establish a unified coordinate system, establish a robot reference moving trajectory according to the pipeline extension image generated by the imaging subsystem, and select the central extension axis of the pipeline as the reference trajectory; within the effective time of the image, Replace the moving trajectory of the robot with a broken line connected by several discontinuous points. The discontinuous point is the position of the robot measured by the magnetic positioning subsystem; when determining the direction of the guiding magnetic field, when the scale of the robot is much smaller than that of the pipeline When the length of , the robot can be regarded as a mass point, assuming that the robot is located at p 0 (x 0 , y 0 , z 0 ) at time t=t 0 , within the range allowed by the position resolution of the magnetic positioning subsystem, the elapsed time Δt, Δt →0, the micro-robot moves to point p 1 (x 1 , y 1 , z 1 ), and then finds a point on the reference trajectory, which is the orthogonal projection of p 1 on the reference trajectory, and calculates The directional derivative of the tangent direction at the projected point on the trajectory, and the directional derivative from point p 0 to p 1 , the difference between the two directional derivatives is calculated by the program, and the difference is the time t=t 0 +Δt required Direction correction value; finally, the direction correction value is converted into the control parameter of the guiding magnetic field, that is, the correction value of the current in the coil, and the computer transmits this correction value from the interface circuit to the magnetic guidance subsystem power supply unit, and finally generates the required guiding magnetic field .

本子系统是根据磁场力原理设计的,即处于外磁场中的磁体会受到力的作用而发生偏转。在均匀磁场中,永磁磁块受到力偶矩

Figure C20061016549500081
的作用,
Figure C20061016549500082
可表示为 T ρ = P ρ × B ρ , 式中
Figure C20061016549500084
为磁矩,等于磁块的磁化强度矢量
Figure C20061016549500085
在磁块体积上的积分,在数值上有P=∫vMdv,
Figure C20061016549500086
为外部磁场的磁感应强度矢量。当磁块磁场的方向与外磁场正交时,力偶矩
Figure C20061016549500087
最大。This subsystem is designed according to the principle of magnetic field force, that is, the magnet in the external magnetic field will be deflected under the action of force. In a uniform magnetic field, the permanent magnet block is subjected to a couple moment
Figure C20061016549500081
role,
Figure C20061016549500082
can be expressed as T ρ = P ρ × B ρ , In the formula
Figure C20061016549500084
is the magnetic moment, which is equal to the magnetization vector of the magnetic block
Figure C20061016549500085
The integral on the volume of the magnetic block has P= ∫v Mdv in value,
Figure C20061016549500086
is the magnetic induction vector of the external magnetic field. When the direction of the magnetic field of the magnetic block is perpendicular to the external magnetic field, the moment of the couple
Figure C20061016549500087
maximum.

本子系统由三组互相正交的亥姆霍兹线圈与电源装置组成,可以在中心区域产生均匀磁场,每组线圈又由两对互相平行的圆形线圈构成,两对线圈之间的间距等于线圈半径。通过调节线圈电流,导向磁场的磁感应强度在数值和方向上均连续可调。电源装置接收计算机求得的导向磁场控制参数,调整每组线圈产生的磁感应强度

Figure C20061016549500089
i=x,y,z,分别代表空间直角坐标系中的三个分量。对三个磁场分量做矢量叠加后,得到导向磁感应强度 This subsystem consists of three sets of mutually orthogonal Helmholtz coils and a power supply device, which can generate a uniform magnetic field in the central area. Each set of coils is composed of two pairs of circular coils parallel to each other. The distance between the two pairs of coils is equal to coil radius. By adjusting the coil current, the magnetic induction intensity of the guiding magnetic field It is continuously adjustable in value and direction. The power supply device receives the control parameters of the guiding magnetic field obtained by the computer, and adjusts the magnetic induction intensity generated by each group of coils
Figure C20061016549500089
i=x, y, z represent three components in the space Cartesian coordinate system respectively. After vector superposition of the three magnetic field components, the guiding magnetic induction intensity is obtained

根据毕奥-萨伐尔定律,亥姆霍兹线圈产生的磁场为According to the Biot-Savart law, the magnetic field generated by the Helmholtz coil is

Figure C200610165495000811
(2)
Figure C200610165495000811
(2)

式中,I为线圈中电流强度,

Figure C200610165495000812
为线圈上微线元
Figure C200610165495000813
所产生的磁场,
Figure C200610165495000814
为微线元
Figure C200610165495000815
相对于感兴趣位置的矢径。In the formula, I is the current intensity in the coil,
Figure C200610165495000812
Microline element on the coil
Figure C200610165495000813
The resulting magnetic field,
Figure C200610165495000814
microline element
Figure C200610165495000815
Radius relative to the location of interest.

2.4计算机控制子系统2.4 Computer Control Subsystem

本子系统是机器人体外导向系统的信号处理与控制中心,由一台计算机与接口电路组成。该子系统通过与磁定位子系统、成像子系统、磁导向子系统以及射频收发器配合工作,控制机器人的移动速度和方向。在主动螺旋驱动结合外磁场姿态控制的混合驱动下,可以实现多种控制策略,并从中找出最优的控制策略,使机器人按照期望的轨迹移动。This subsystem is the signal processing and control center of the robot's external guidance system, and is composed of a computer and an interface circuit. The subsystem controls the moving speed and direction of the robot by cooperating with the magnetic positioning subsystem, imaging subsystem, magnetic guidance subsystem and radio frequency transceiver. Under the hybrid drive of active helical drive combined with external magnetic field attitude control, various control strategies can be realized, and the optimal control strategy can be found to make the robot move according to the desired trajectory.

本子系统通过接口电路连接磁定位子系统、成像子系统以及磁导向子系统,负责数据处理与通信。接口电路主要包括一片模数转换器AD9874、一片数字信号处理器TMS320f2812、一片可编程逻辑器件EPM7128AETC100-10以及一片数模转换器DAC7625。模数转换器负责对模拟输入数据进行放大、模数转换以及滤波,输出数字信号至数字信号处理器,数模转换器负责将计算机产生的数据信号和控制信号转换为模拟信号,并输出给其他子系统。数字信号处理器负责对原始图像数据进行快速傅立时变换,可编程逻辑器件对接口电路中的模数转换器等器件实施逻辑控制,包括寄存器参数设置、中断管理等。This subsystem is connected to the magnetic positioning subsystem, the imaging subsystem and the magnetic guidance subsystem through the interface circuit, and is responsible for data processing and communication. The interface circuit mainly includes a piece of analog-to-digital converter AD9874, a piece of digital signal processor TMS320f2812, a piece of programmable logic device EPM7128AETC100-10 and a piece of digital-to-analog converter DAC7625. The analog-to-digital converter is responsible for amplifying, converting and filtering the analog input data, and outputting the digital signal to the digital signal processor. The digital-analog converter is responsible for converting the data signal and control signal generated by the computer into an analog signal and outputting it to other subsystem. The digital signal processor is responsible for the fast Fourier transform of the original image data, and the programmable logic device implements logic control on the analog-to-digital converter and other devices in the interface circuit, including register parameter setting and interrupt management.

本发明工作过程简述如下:The working process of the present invention is briefly described as follows:

首先,操作者控制移动床将受检管路移至成像区域,并将机器人放至管路始端。然后,成像子系统对第一段管路进行成像并显示,建立磁定位与磁导向所需的统一坐标系,确定机器人初始坐标。操作者通过计算机使射频发射器发出微电动机启动信号,由机器人体内的射频接收器接收,使机器人进入待机状态。在机器人移动过程中,操作者通过体外导向系统连续调整机器人的移动方向与速度,控制机器人按照管路的延伸方向移动。当机器人需要向后移动时,则借助射频信号控制,使机器人体内的微电动机反转,带动机器人向后移动。最后,当机器人完成所给探寻任务,需控制机器人反向退出管路,与前向移动时类似,操作者通过控制体外部导向系统使其反向移动,退出管路。First, the operator controls the moving bed to move the inspected pipeline to the imaging area, and puts the robot at the beginning of the pipeline. Then, the imaging subsystem images and displays the first section of pipeline, establishes a unified coordinate system required for magnetic positioning and magnetic guidance, and determines the initial coordinates of the robot. The operator uses the computer to make the radio frequency transmitter send out the start signal of the micro motor, which is received by the radio frequency receiver in the robot body, so that the robot enters the standby state. During the movement of the robot, the operator continuously adjusts the moving direction and speed of the robot through the external guidance system, and controls the robot to move in the direction in which the pipeline extends. When the robot needs to move backward, the micro-motor in the robot body is reversed by means of radio frequency signal control to drive the robot to move backward. Finally, when the robot completes the given search task, it needs to control the robot to exit the pipeline in the reverse direction. Similar to the forward movement, the operator moves in the reverse direction and exits the pipeline by controlling the external guidance system of the body.

本发明采用主动螺旋推进结合导向磁场姿态控制的混合驱动方式,在一定程度上解决了机器人体积微型化与移动灵活性之间的矛盾,以期在人体内部诊疗中发挥重要作用。另外,本发明还可应用于工业设备非磁性细小管路的探测。本发明通过将机器人技术、磁定位与导向技术、断层成像技术、数据处理技术以及自动控制等技术结合起来,实现无创伤诊疗或探测。The present invention adopts a hybrid drive mode of active screw propulsion combined with guided magnetic field attitude control, which solves the contradiction between the miniaturization of the robot volume and the mobility flexibility to a certain extent, and is expected to play an important role in the internal diagnosis and treatment of the human body. In addition, the invention can also be applied to the detection of non-magnetic small pipelines of industrial equipment. The invention realizes non-invasive diagnosis and treatment or detection by combining robot technology, magnetic positioning and guidance technology, tomographic imaging technology, data processing technology and automatic control technology.

另外,在该混合驱动方式中,本发明采用巨磁电阻(GMR)传感器检测微型机器人内永磁磁块磁场的方法,比现有的其它磁定位方法更简单、更精确。In addition, in the hybrid driving mode, the present invention adopts a giant magnetoresistance (GMR) sensor to detect the magnetic field of the permanent magnet block in the micro-robot, which is simpler and more accurate than other existing magnetic positioning methods.

附图说明 Description of drawings

图1为微型机器人内部结构示意图;图中:1微型机器人,2管路,3管路内介质,1a机身,1b永磁磁块,1c机壳,1d射频接收器,1e微型电池,1f微电动机,1g蜗杆,1h尾部旋转机构,1i尾部。Figure 1 is a schematic diagram of the internal structure of the micro-robot; in the figure: 1 micro-robot, 2 pipelines, 3 medium in the pipeline, 1a body, 1b permanent magnet block, 1c casing, 1d radio frequency receiver, 1e micro-battery, 1f Micro motor, 1g worm, 1h tail rotating mechanism, 1i tail.

图2为本发明体外导向系统组成结构方框图;图中:4磁导向子系统,5磁定位子系统,6成像子系统,7计算机控制子系统。Fig. 2 is a structural block diagram of the in vitro guidance system of the present invention; in the figure: 4 magnetic guidance subsystems, 5 magnetic positioning subsystems, 6 imaging subsystems, and 7 computer control subsystems.

图3为磁导向子系统示意图;图中:4a x方向亥姆霍兹线圈,4b y方向亥姆霍兹线圈,4c z方向亥姆霍兹线圈,4d磁导向电源装置,8受检者,9移动床。Figure 3 is a schematic diagram of the magnetic guidance subsystem; in the figure: 4a Helmholtz coils in the x direction, 4b Helmholtz coils in the y direction, 4c Helmholtz coils in the z direction, 4d magnetic guidance power supply device, 8 subjects, 9 mobile beds.

图4为磁定位子系统示意图;图中,5a巨磁电阻,5b磁定位电源装置,5c导线。Figure 4 is a schematic diagram of the magnetic positioning subsystem; in the figure, 5a is a giant magnetoresistance, 5b is a magnetic positioning power supply device, and 5c is a wire.

图5为成像子系统示意图;图中,6a探测器圆周阵列,6b圆周扫描轨道,6c X射线发射器,6d成像电源装置。Figure 5 is a schematic diagram of the imaging subsystem; in the figure, 6a detector circular array, 6b circular scanning track, 6c X-ray emitter, 6d imaging power supply device.

图6为磁定位求逆算法流程图;Fig. 6 is a flow chart of the magnetic positioning inversion algorithm;

图7为磁导向算法流程图。Figure 7 is a flow chart of the magneto-steering algorithm.

具体实施方式 Detailed ways

下面结合附图及具体实施方式进一步说明本发明。The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

微型机器人1的内部结构示意如图1所示,其前端光滑,外壁无突起或沟槽,外壳采用光滑的、具有一定韧性和柔性的医用材料包覆,与管路2内壁摩擦较小。永磁磁块1b外周面有螺旋槽,与机身1a内部前端的螺旋槽密闭配合。尾部旋转机构1h与尾部1i通过从机身内伸出的旋转杆形成固定连接。尾部旋转机构1h由蜗杆1g、蜗轮、凸轮、旋转杆、底板、铰链、永磁铁与电磁线圈组成,蜗杆1g安装在微电动机1f主轴上,蜗轮和凸轮共轴布置,蜗轮的转轴安装在底板上,该底板粘贴在机身上,旋转杆安装在铰链上,铰链固定在微电动机的壳体上,旋转杆的一端与尾部固定连接,其另一端搁置在凸轮上,永久磁铁固定在旋转杆上,电磁线圈位于永久磁铁的外侧。尾部1i采用光滑的、柔韧性较好的生物医学材料制成。射频接收器1d安装在机身1a后端内周面上。微电动机1f与射频接收器1d由装在机身1a内的微型电池1e供电,该电池1e安装在机身1a后端内周面上,位置与射频接收器1d对称。The internal structure of the micro-robot 1 is shown in Figure 1. Its front end is smooth, and its outer wall has no protrusions or grooves. There is a spiral groove on the outer peripheral surface of the permanent magnet block 1b, which is airtightly matched with the spiral groove at the inner front end of the fuselage 1a. The tail rotating mechanism 1h is fixedly connected with the tail 1i through a rotating rod protruding from the inside of the fuselage. The tail rotating mechanism 1h is composed of a worm 1g, a worm gear, a cam, a rotating rod, a bottom plate, a hinge, a permanent magnet and an electromagnetic coil. The worm 1g is installed on the main shaft of the micromotor 1f. The worm wheel and the cam are coaxially arranged, and the rotating shaft of the worm wheel is installed on the bottom plate. , the bottom plate is pasted on the fuselage, the rotating rod is installed on the hinge, the hinge is fixed on the housing of the micro motor, one end of the rotating rod is fixedly connected with the tail, the other end rests on the cam, and the permanent magnet is fixed on the rotating rod , the electromagnetic coil is located outside the permanent magnet. Tail 1i is made of smooth, flexible biomedical material. The radio frequency receiver 1d is installed on the inner peripheral surface of the rear end of the fuselage 1a. The micro motor 1f and the radio frequency receiver 1d are powered by a micro battery 1e installed in the body 1a, and the battery 1e is installed on the inner peripheral surface of the rear end of the body 1a, and its position is symmetrical with the radio frequency receiver 1d.

微型机器人1的轴向移动速率由射频发射器与射频接收器1d控制,射频发射器属于计算机控制子系统7的一部分,集成在接口电路上。射频接收器1d控制微电动机1f的工作状态,包括其转速与电源接通极性,微电动机1f通过蜗杆1g与尾部旋转机构1h相连接,带动微型机器人1在管路内介质3中前向或后向移动。The axial movement rate of the micro-robot 1 is controlled by a radio frequency transmitter and a radio frequency receiver 1d. The radio frequency transmitter is part of the computer control subsystem 7 and is integrated on the interface circuit. The radio frequency receiver 1d controls the working state of the micromotor 1f, including its rotational speed and the polarity of the power supply. The micromotor 1f is connected with the tail rotation mechanism 1h through the worm 1g, and drives the microrobot 1 to move forward or backward in the medium 3 in the pipeline. Move backwards.

永磁磁块1b采用高性能稀土永磁材料制成,如铷铁硼永磁材料等。磁定位子系统5通过感知永磁磁块1b所激发的磁场,对微型机器人1在管路2中的位置进行实时测量。磁导向子系统4能够在永磁磁块1b所在区域激发出沿所需方向的导向磁场,永磁磁块1b受导向磁场的作用被迫沿导向磁场取向,以使微型机器人1沿期望路径移动。The permanent magnet block 1b is made of high-performance rare earth permanent magnet materials, such as NdFeB permanent magnet materials. The magnetic positioning subsystem 5 measures the position of the micro robot 1 in the pipeline 2 in real time by sensing the magnetic field excited by the permanent magnet block 1b. The magnetic guiding subsystem 4 can excite a guiding magnetic field along the required direction in the area where the permanent magnet block 1b is located, and the permanent magnetic block 1b is forced to be oriented along the guiding magnetic field by the action of the guiding magnetic field, so that the micro robot 1 moves along the desired path .

如图2所示,本发明体外导向系统由磁导向子系统4、磁定位子系统5、成像子系统6以及计算机控制子系统7组成。As shown in FIG. 2 , the extracorporeal guidance system of the present invention is composed of a magnetic guidance subsystem 4 , a magnetic positioning subsystem 5 , an imaging subsystem 6 and a computer control subsystem 7 .

计算机控制子系统7由一台计算机与接口电路组成,用于计算、协调及控制微型机器人1、磁导向子系统4、磁定位子系统5以及成像子系统6的工作,其作为各种数据与信号的接收、处理及发送中心,同时为操作者提供人机交互界面。除计算机控制子系统7外,磁导向子系统4、磁定位子系统5以及成像子系统6与微型机器人1之间也存在逻辑关系。The computer control subsystem 7 is composed of a computer and an interface circuit, and is used for calculating, coordinating and controlling the work of the micro-robot 1, the magnetic guidance subsystem 4, the magnetic positioning subsystem 5 and the imaging subsystem 6. The signal receiving, processing and sending center also provides the operator with a human-computer interaction interface. In addition to the computer control subsystem 7 , there is also a logical relationship between the magnetic guidance subsystem 4 , the magnetic positioning subsystem 5 , and the imaging subsystem 6 and the micro robot 1 .

图2所示的逻辑关系包括:成像子系统6对待成像区域进行若干断层图像扫描,所得原始图像数据被送入计算机控制子系统7进行图像重建并显示;磁定位子系统5对微型机器人1内部永磁磁块1b通过磁场进行定位,所得含有位置信息的信号被送入计算机控制子系统7由磁定位求逆算法进行位置重建;计算机控制子系统7产生导向磁场控制信号并传递至磁导向子系统4,对微型机器人1进行导向控制;计算机控制子系统7发送射频控制信号至微型机器人1。The logical relationship shown in Figure 2 includes: the imaging subsystem 6 scans several tomographic images of the area to be imaged, and the obtained original image data is sent to the computer control subsystem 7 for image reconstruction and display; The permanent magnet block 1b is positioned by the magnetic field, and the obtained signal containing position information is sent to the computer control subsystem 7 to reconstruct the position by the magnetic positioning inversion algorithm; the computer control subsystem 7 generates the control signal of the guiding magnetic field and transmits it to the magnetic director System 4 is used to guide and control the micro-robot 1 ; the computer control subsystem 7 sends radio frequency control signals to the micro-robot 1 .

如图3所示的磁导向子系统4中,包括三组亥姆霍兹线圈4a、4b和4c,设计线圈几何参数时,考虑到将受检者8由移动床9送入磁导向子系统4时不使其产生压迫感,三组亥姆霍兹圆形线圈4a、4b和4c直径相等,每组线圈两两正交,并由两个镜像对称的线圈组成,间距0.6米。磁导向电源装置4d在计算机控制子系统7的控制下,用于向线圈4a、4b和4c供应可调直流电流。In the magnetic guidance subsystem 4 shown in Figure 3, including three groups of Helmholtz coils 4a, 4b and 4c, when designing the coil geometric parameters, it is considered that the subject 8 is sent into the magnetic guidance subsystem by the moving bed 9 4 o'clock does not make it feel oppressive, three groups of Helmholtz circular coils 4a, 4b and 4c have the same diameter, each group of coils is orthogonal to each other, and is composed of two mirror-image symmetrical coils with a distance of 0.6 meters. The magneto-steering power supply device 4d is used to supply adjustable DC current to the coils 4a, 4b and 4c under the control of the computer control subsystem 7 .

如图4所示的磁定位子系统5中,采用8个巨磁电阻5a,分布于一虚拟的罩于被测管路2外面的长方体的8个顶点上,以测量微型机器人1内永磁磁块1b磁场的空间分布。根据测得的结果,通过求逆算法获得微型机器人1的位置。磁定位子系统电源装置5b负责向巨磁电阻5a提供恒定直流电压,导线5c用于将巨磁电阻5a与电源装置5b连成一个串并联回路,即将巨磁电阻5a分成两组,每组中采用串联方式,组间采用并联方式。In the magnetic positioning subsystem 5 shown in Figure 4, 8 giant magnetoresistors 5a are used to distribute on the 8 vertices of a cuboid covering the outside of the tested pipeline 2 to measure the permanent magnet in the micro robot 1. Spatial distribution of magnetic field of magnetic block 1b. According to the measured results, the position of the micro robot 1 is obtained through an inversion algorithm. The magnetic positioning subsystem power supply device 5b is responsible for providing a constant DC voltage to the giant magnetoresistance 5a, and the wire 5c is used to connect the giant magnetoresistance 5a and the power supply device 5b into a series-parallel circuit, that is, the giant magnetoresistance 5a is divided into two groups, each group The series mode is adopted, and the parallel mode is adopted between the groups.

如图5所示的成像子系统6,X射线发射器6c对管路2的一系列断层进行若干次圆周扫描。每一次扫描中,X射线发射器6c在圆周扫描轨道6b上的每一次步进,对应于探测器圆周阵列6a中的一个探测器,并得到一个原始图像数据。探测器圆周阵列6a包含若干个探测器,当X射线发射器6c做完一次圆周扫描,相应断层的扫描数据被送入计算机控制子系统7进行图像重建,获得一幅断层图像,对一段管路的成像是通过对若干幅断层图像进行合成而得到的。成像电源装置6d负责给X射线发射器6c与探测器圆周阵列6a供电。As shown in the imaging subsystem 6 in FIG. 5 , the X-ray emitter 6 c performs several circular scans on a series of slices of the pipeline 2 . In each scan, each step of the X-ray emitter 6c on the circular scanning track 6b corresponds to a detector in the detector circular array 6a, and a raw image data is obtained. The detector circular array 6a includes several detectors. When the X-ray emitter 6c completes a circular scan, the scanning data of the corresponding slice is sent to the computer control subsystem 7 for image reconstruction to obtain a slice image. The imaging is obtained by synthesizing several tomographic images. The imaging power supply device 6d is responsible for supplying power to the X-ray emitter 6c and the detector circular array 6a.

移动床9为非磁性床,根据断层成像子系统5以及磁导向子系统2的需要,并考虑到微型机器人1在管路2中的移动特点,其运动形式为以轴向平移为主、兼可在垂直于受检者8轴线方向的平面内微位移,即具备三个自由度,以将感兴趣区域送至有效导向磁场区域或成像区域。The moving bed 9 is a non-magnetic bed. According to the needs of the tomographic imaging subsystem 5 and the magnetic guidance subsystem 2, and considering the moving characteristics of the micro robot 1 in the pipeline 2, its movement form is mainly axial translation, combined with It can be slightly displaced in a plane perpendicular to the axis direction of the subject 8, that is, it has three degrees of freedom, so as to send the region of interest to the effective guidance magnetic field region or imaging region.

如图6所示的磁定位求逆算法流程图,首先确定统一坐标系,给出各巨磁电阻5a在坐标系中的空间坐标;根据成像子系统6提供的管路2几何形状,选取管路2的几何中心轴作为机器人1参考移动轨迹;对于给定的永磁磁块1b,通过(1)式计算当其位于参考移动轨迹上每一点时各巨磁电阻5a所在位置的磁感应强度值,并预测各巨磁电阻5a的测量值,建立一张位置-磁场对应数据表;然后,在机器人1体外控制系统的配合下使机器人1在管路2中尽可能沿参考移动轨迹移动,并在移动过程中连续记录每个巨磁电阻5a的测量值;最后,由各测量值,结合位置-磁场对应数据表进行曲线拟合,获得对应于每一时刻机器人1的近似位置。The flow chart of the magnetic positioning inversion algorithm shown in Figure 6 first determines the unified coordinate system, and provides the spatial coordinates of each giant magnetoresistance 5a in the coordinate system; according to the geometric shape of the pipeline 2 provided by the imaging subsystem 6, select the pipeline The geometric central axis of road 2 is used as the reference trajectory of robot 1; for a given permanent magnet block 1b, the magnetic induction intensity value of each giant magnetoresistance 5a is calculated when it is located at each point on the reference trajectory by formula (1) , and predict the measured value of each giant magnetoresistance 5a, and establish a position-magnetic field correspondence data table; then, with the cooperation of the external control system of robot 1, make robot 1 move as far as possible along the reference moving track in pipeline 2, and Continuously record the measurement value of each giant magnetoresistance 5a during the moving process; finally, perform curve fitting based on each measurement value combined with the position-magnetic field corresponding data table, and obtain the approximate position corresponding to each moment of the robot 1 .

如图7所示的磁导向算法流程图,首先,根据成像子系统6生成的管路2延伸图像建立一条机器人1参考移动轨迹,选取管路2的几何中心轴为参考轨迹。在当前图像的有效时间内,将磁定位子系统5测得的一系列不连续机器人位置坐标连接起来获得一条折线路径。判断导向磁场方向的原理如下:当机器人1的尺寸远远小于管路的长度时,可将机器人1看成质点,假设t=t0时刻机器人1位于p0(x0,y0,z0),在不超过磁定位子系统位置分辨率的情况下,经过时间段Δt,Δt→0,机器人1移动至p1(x1,y1,z1)点;在参考移动轨迹上找一点p′1,该点为p1点在参考移动轨迹上的正交投影,然后计算出参考移动轨迹在p′1点切线方向的方向导数,以及由p0点指向p1点的方向导数;计算出上述两方向导数之差,此差值即为所求的导向磁场方向修正值。最后将方向修正值转化为对应于p1点的导向磁场控制参数,并由接口电路传送至磁导向子系统4的电源装置4d,最终使机器人1尽可能沿参考移动轨迹移动。As shown in the flow chart of the magneto-steering algorithm in Fig. 7, firstly, a reference moving trajectory of the robot 1 is established according to the extended image of the pipeline 2 generated by the imaging subsystem 6, and the geometric central axis of the pipeline 2 is selected as the reference trajectory. Within the effective time of the current image, a series of discontinuous robot position coordinates measured by the magnetic positioning subsystem 5 are connected to obtain a polyline path. The principle of judging the direction of the guiding magnetic field is as follows: when the size of the robot 1 is much smaller than the length of the pipeline, the robot 1 can be regarded as a mass point, assuming that the robot 1 is located at p 0 (x 0 , y 0 , z 0 ), without exceeding the position resolution of the magnetic positioning subsystem, after the time period Δt, Δt→0, robot 1 moves to point p 1 (x 1 , y 1 , z 1 ); find a point on the reference trajectory p′ 1 , this point is the orthogonal projection of point p 1 on the reference moving trajectory, and then calculate the directional derivative of the reference moving trajectory in the tangential direction of point p′ 1 , and the directional derivative from point p 0 to point p 1 ; Calculate the difference between the above-mentioned two direction derivatives, and this difference is the correction value of the steering magnetic field direction. Finally, the direction correction value is converted into the guidance magnetic field control parameter corresponding to point p1 , and is transmitted by the interface circuit to the power supply device 4d of the magnetic guidance subsystem 4, and finally the robot 1 is moved along the reference movement trajectory as much as possible.

本发明的具体工作流程为:Concrete workflow of the present invention is:

1.首先开启计算机控制子系统7,并打开与微型机器人1、磁导向子系统4、磁定位子系统5以及成像子系统6连接的接口电路。1. First, turn on the computer control subsystem 7, and turn on the interface circuit connected with the micro robot 1, the magnetic guidance subsystem 4, the magnetic positioning subsystem 5 and the imaging subsystem 6.

2.开启成像子系统6,在移动床9的配合下,调整待成像区域与X射线扫描平面间的相对位置,将相应断层,即管路2的始端调整至成像视野。2. Turn on the imaging subsystem 6, and with the cooperation of the moving bed 9, adjust the relative position between the area to be imaged and the X-ray scanning plane, and adjust the corresponding slice, that is, the beginning of the pipeline 2, to the imaging field of view.

3.开启磁定位子系统5,给巨磁电阻5a串并联电路加固定电压。将微型机器人1放置于管路2始端,计算机控制子系统7发出射频微电动机控制信号至微型机器人1内部的射频接收器1d,并在射频接收器1d控制下,使微电动机1f进入待机状态。接下来,磁定位子系统5测量微型机器人1的初始位置,并将数据送入计算机控制子系统7进行处理。3. Turn on the magnetic positioning subsystem 5, and apply a fixed voltage to the series-parallel circuit of the giant magnetoresistance 5a. Place the micro-robot 1 at the beginning of the pipeline 2, and the computer control subsystem 7 sends a radio-frequency micro-motor control signal to the radio-frequency receiver 1d inside the micro-robot 1, and under the control of the radio-frequency receiver 1d, the micro-motor 1f enters a standby state. Next, the magnetic positioning subsystem 5 measures the initial position of the micro robot 1, and sends the data to the computer control subsystem 7 for processing.

利用磁定位算法,由计算机控制子系统7计算出永磁磁块1b的初始位置,即微型机器人1的初始位置。需要注意的是,成像子系统6对管路2与微型机器人1成像的工作是周期性进行的,而微型机器人1与管路2间的相对位置,是通过将磁定位子系统5对微型机器人1实时测得的位置与每一帧图像相结合得到的。Using the magnetic positioning algorithm, the computer control subsystem 7 calculates the initial position of the permanent magnet block 1 b, that is, the initial position of the micro robot 1 . It should be noted that the work of the imaging subsystem 6 on the imaging of the pipeline 2 and the microrobot 1 is carried out periodically, and the relative position between the microrobot 1 and the pipeline 2 is obtained by aligning the magnetic positioning subsystem 5 with the microrobot. 1 The position measured in real time is combined with each frame of image.

4.结合第三步中得到的管路2与微型机器人1相对位置,操作者根据微型机器人1所要实现的探测目的,决定其期望移动方向。并根据该期望方向,利用磁导向算法,由计算机控制子系统7计算出关于该期望方向的一组磁感应强度,

Figure C20061016549500121
叠加后得到的总磁感应强度的方向即为期望的微型机器人1移动方向。4. Combined with the relative position of the pipeline 2 and the micro-robot 1 obtained in the third step, the operator determines the desired movement direction of the micro-robot 1 according to the detection purpose to be realized by the micro-robot 1 . And according to the desired direction, using the magnetic guidance algorithm, the computer control subsystem 7 calculates a group of magnetic induction intensities about the desired direction,
Figure C20061016549500121
The total magnetic induction intensity obtained after superposition The direction of is the desired moving direction of the micro-robot 1 .

5.开启磁导向子系统4。通过接口电路,计算机控制子系统5将第四步中得到的导向磁场控制参数传送至磁导向子系统4的电源装置4d,该电源装置4d将导向磁场控制参数变换为三组亥姆霍兹线圈4a、4b和4c中电流强度的变化量。根据安培环路定理,

Figure C20061016549500123
在线圈中通以直流电流会在其周围空间中激发出恒定的磁场。本发明中,利用电源装置4d控制4a、4b、4c三组线圈中直流电流的大小与方向,在磁导向子系统4的中心区域得到所需均匀导向磁场
Figure C20061016549500124
5. Turn on the magnetic guidance subsystem 4. Through the interface circuit, the computer control subsystem 5 transmits the steering magnetic field control parameters obtained in the fourth step to the power supply device 4d of the magnetic steering subsystem 4, and the power supply device 4d transforms the steering magnetic field control parameters into three sets of Helmholtz coils Variation of current intensity in 4a, 4b and 4c. According to the Ampere loop theorem,
Figure C20061016549500123
Passing a direct current through the coil excites a constant magnetic field in the space around it. In the present invention, the magnitude and direction of the direct current in the three groups of coils 4a, 4b, and 4c are controlled by the power supply device 4d, and the required uniform guiding magnetic field is obtained in the central area of the magnetic guiding subsystem 4
Figure C20061016549500124

6.在外部导向磁场

Figure C20061016549500125
作用下,微型机器人1中的永磁磁块1b将产生磁转矩,迫使永磁磁块1b沿导向磁场方向取向。同时,计算机控制子系统7通过射频收发器启动微电动机1f,由蜗杆1g带动尾部旋转机构1h与尾部1i,使微型机器人1沿指定方向前进。6. Guide the magnetic field externally
Figure C20061016549500125
Under the action, the permanent magnet block 1b in the micro robot 1 will generate a magnetic torque, forcing the permanent magnet block 1b to be oriented along the direction of the guiding magnetic field. At the same time, the computer control subsystem 7 activates the micromotor 1f through the radio frequency transceiver, and the worm 1g drives the tail rotating mechanism 1h and the tail 1i to make the microrobot 1 move forward in a specified direction.

7.微型机器人1移动过程中移动方向与速度的连续控制。由于管路2的内部尺寸与延伸方向的不确定性,必须随时调整微型机器人1的移动方向与速度,就需要操作者通过微型机器人1体外导向系统时时获得管路2与微型机器人1的相对位置信息,并通过体外导向控制系统使微型机器人1最终移动至指定位置。7. Continuous control of the moving direction and speed of the micro robot 1 during the moving process. Due to the uncertainty of the internal size and extension direction of the pipeline 2, the moving direction and speed of the micro-robot 1 must be adjusted at any time, which requires the operator to constantly obtain the relative position of the pipeline 2 and the micro-robot 1 through the external guidance system of the micro-robot 1 information, and finally move the micro robot 1 to the designated position through the in vitro guidance control system.

8.当微型机器人1完成所给探寻任务,或者因为遇到障碍等原因需要向后移动时,与前向移动时类似,计算机控制子系统7通过射频发射器发射射频驱动信号至微型机器人1,使微电动机1f驱动尾部1i反向转动,即可实现使微型机器人1向后移动。而且,与前进时一样,后退过程也需要在体外导向控制系统的控制下进行。8. When the micro-robot 1 completes the given search task, or needs to move backward due to encountering obstacles, etc., similar to when moving forward, the computer control subsystem 7 transmits a radio frequency drive signal to the micro-robot 1 through a radio frequency transmitter, The micro-motor 1f drives the tail part 1i to reversely rotate, so that the micro-robot 1 can move backward. And, the same as advancing, the retreating process also needs to be carried out under the control of the in vitro guidance control system.

Claims (6)

1、一种微型机器人,机身[1a]内部镂空,布置有射频接收器[1d]、微型电池[1e]与微电动机[1f],其特征在于机身[1a]内部前端周面上开有一个用于布置永磁磁块[1b]的螺旋槽,永磁磁块[1b]外周面有螺旋槽,与机身[1a]内部前端环形螺旋槽密闭配合;机身[1a]底部开有一个轴向通孔;尾部旋转机构[1h]与尾部[1i]通过从机身[1a]通孔内伸出的旋转杆固定连接,旋转杆与机身[1a]采用高弹性密封膜密封;微型机器人[1]前端光滑,外壁表面无突起或沟槽;射频接收器[1d]安装在机身[1a]后端内周面上,微电动机[1f]与射频接收器[1d]由微型电池[1e]供电,该电池[1e]安装在机身[1a]后端内周面上,位置与射频接收器[1d]对称;尾部旋转机构[1h]通过蜗杆[1g]与微电动机[1f]主轴连接,带动微型机器人[1]向前或向后移动;所述尾部旋转机构[1h]由蜗杆[1g]、蜗轮、凸轮、旋转杆、底板、铰链、永磁铁与电磁线圈组成,蜗杆[1g]安装在微电动机[1f]主轴上,蜗轮和凸轮共轴布置,蜗轮的转轴安装在底板上,所述的底板粘贴在机身[1a]上,旋转杆安装在铰链上,所述的铰链固定在微电动机[1f]的壳体上,旋转杆的一端与尾部[1i]固定连接,旋转杆的另一端与凸轮连接,永磁铁固定在旋转杆上,电磁线圈位于永磁铁的外侧。1. A micro-robot, the inside of the fuselage [1a] is hollowed out, and a radio frequency receiver [1d], a micro-battery [1e] and a micro-motor [1f] are arranged. There is a spiral groove for arranging the permanent magnet block [1b]. The outer peripheral surface of the permanent magnet block [1b] has a spiral groove, which is tightly matched with the ring spiral groove at the front end of the fuselage [1a]; the bottom of the fuselage [1a] is opened There is an axial through hole; the tail rotating mechanism [1h] is fixedly connected with the tail [1i] through the rotating rod protruding from the through hole of the fuselage [1a], and the rotating rod and the fuselage [1a] are sealed with a highly elastic sealing film The front end of the micro-robot [1] is smooth, and there are no protrusions or grooves on the surface of the outer wall; the radio frequency receiver [1d] is installed on the inner peripheral surface of the rear end of the fuselage [1a], and the micro-motor [1f] and the radio frequency receiver [1d] are composed of The micro battery [1e] supplies power, and the battery [1e] is installed on the inner peripheral surface of the rear end of the fuselage [1a], and its position is symmetrical to that of the radio frequency receiver [1d]; [1f] The main shaft is connected to drive the micro robot [1] to move forward or backward; the tail rotation mechanism [1h] is composed of a worm [1g], a worm wheel, a cam, a rotating rod, a bottom plate, a hinge, a permanent magnet and an electromagnetic coil , the worm [1g] is installed on the main shaft of the micro-motor [1f], the worm gear and the cam are coaxially arranged, the rotating shaft of the worm gear is installed on the base plate, the base plate is pasted on the fuselage [1a], and the rotating rod is installed on the hinge, The hinge is fixed on the housing of the micro motor [1f], one end of the rotating rod is fixedly connected to the tail [1i], the other end of the rotating rod is connected to the cam, the permanent magnet is fixed on the rotating rod, and the electromagnetic coil is located on the permanent magnet. outside. 2、一种用于权利要求1所述微型机器人的体外导向系统,其特征在于包括磁导向子系统[4]、磁定位子系统[5]、成像子系统[6]以及计算机控制子系统[7];计算机控制子系统[7]分别与微型机器人[1]、磁导向子系统[4]、磁定位子系统[5]以及成像子系统[6]连接;成像子系统[6]对待探测区域进行连续断层平面扫描,所得原始图像数据被送入计算机控制子系统[7]进行图像重建并显示,磁定位子系统[5]对微型机器人[1]内部的永磁磁块[1b]进行磁定位,所得原始位置信息被送入计算机控制子系统[7]进行位置重建,计算机控制子系统[7]产生导向控制信息并传递至磁导向子系统[4],磁导向子系统[4]对微型机器人[1]进行导向控制,计算机控制子系统[7]发送射频控制信号至微型机器人[1]。2. An in vitro guidance system for a microrobot as claimed in claim 1, characterized in that it comprises a magnetic guidance subsystem [4], a magnetic positioning subsystem [5], an imaging subsystem [6] and a computer control subsystem [ 7]; the computer control subsystem [7] is connected with the micro robot [1], the magnetic guide subsystem [4], the magnetic positioning subsystem [5] and the imaging subsystem [6] respectively; the imaging subsystem [6] is to be detected The area is scanned continuously tomographically, and the original image data obtained are sent to the computer control subsystem [7] for image reconstruction and display, and the magnetic positioning subsystem [5] carries out the Magnetic positioning, the original position information obtained is sent to the computer control subsystem [7] for position reconstruction, the computer control subsystem [7] generates guidance control information and transmits it to the magnetic guidance subsystem [4], the magnetic guidance subsystem [4] The micro-robot [1] is guided and controlled, and the computer control subsystem [7] sends a radio frequency control signal to the micro-robot [1]. 3、按照权利要求2所述的微型机器人体外导向系统,其特征在于所述的磁导向子系统[4]中,三组亥姆霍兹线圈[4a、4b、4c]均为轴对称结构,直径相等,两两正交;每组线圈分别由两对互相平行的圆形线圈组成。3. The in vitro guidance system for microrobots according to claim 2, characterized in that in the magnetic guidance subsystem [4], the three sets of Helmholtz coils [4a, 4b, 4c] are all axisymmetric structures, The diameters are equal, and the pairs are orthogonal; each group of coils is composed of two pairs of circular coils parallel to each other. 4、按照权利要求2所述的微型机器人体外导向系统,其特征在于所述的磁定位子系统[5]中,采用8个巨磁电阻[5a],分两层布置于管路[2]的外部,即在受检者轴线方向上分前后互相平行的两层布置,以实时检测微型机器人[1]内永磁磁块磁场的分布变化,并将检测结果与已知的磁场分布数据进行比拟,通过磁定位求逆算法获得微型机器人[1]的位置信息。4. The in vitro guidance system for microrobots according to claim 2, characterized in that in the magnetic positioning subsystem [5], 8 giant magnetoresistances [5a] are used, arranged in two layers in the pipeline [2] The exterior of the tester is divided into two layers parallel to each other in the direction of the subject's axis to detect the distribution of the magnetic field of the permanent magnet in the micro-robot [1] in real time, and compare the detection results with the known magnetic field distribution data. In comparison, the position information of the micro-robot [1] is obtained through the magnetic positioning inversion algorithm. 5、按照权利要求3所述的微型机器人体外导向系统,其特征在于所述的计算机控制子系统[7]由磁定位求逆算法进行位置重建流程如下:首先确定统一坐标系,给出各巨磁电阻[5a]在坐标系中的空间坐标;根据所述的成像子系统[6]提供的管路[2]几何形状,选取管路[2]的几何中心轴作为机器人[1]参考移动轨迹;对于给定的永磁磁块[1b],计算当其位于参考移动轨迹上每一点时各巨磁电阻[5a]所在位置的磁感应强度值,并预测各巨磁电阻[5a]的测量值,建立一张位置一磁场对应数据表;然后,在机器人[1]体外控制系统的配合下使机器人[1]在管路[2]中尽可能沿参考移动轨迹移动,并在移动过程中连续记录每个巨磁电阻[5a]的测量值;最后,由各测量值,结合位置一磁场对应数据表进行曲线拟合,获得对应于每一时刻机器人[1]的近似位置。5. According to claim 3, the in vitro guidance system for micro-robots is characterized in that the computer control subsystem [7] uses the magnetic positioning inversion algorithm to perform position reconstruction as follows: first determine the unified coordinate system, and give each giant The spatial coordinates of the magnetic resistance [5a] in the coordinate system; according to the geometric shape of the pipeline [2] provided by the imaging subsystem [6], the geometric center axis of the pipeline [2] is selected as the reference movement of the robot [1] trajectory; for a given permanent magnet block [1b], calculate the magnetic induction intensity value of each giant magnetoresistance [5a] when it is located at each point on the reference moving trajectory, and predict the measurement of each giant magnetoresistance [5a] value, establish a position-magnetic field correspondence data table; then, with the cooperation of the external control system of the robot [1], make the robot [1] move along the reference movement track as much as possible in the pipeline [2], and during the movement process Continuously record the measured value of each giant magnetoresistance [5a]; finally, perform curve fitting on each measured value combined with the position-magnetic field corresponding data table to obtain the approximate position corresponding to each moment of the robot [1]. 6、按照权利要求2所述的微型机器人体外导向系统,其特征在于所述的计算机控制子系统[7]通过磁导向算法控制机器人的移动方向的流程如下:首先,根据成像子系统[6]生成的管路[2]延伸图像建立一条机器人[1]参考移动轨迹,选取管路[2]的几何中心轴为参考轨迹;在当前图像的有效时间内,将磁定位子系统[5]测得的一系列不连续机器人位置坐标连接起来获得一条折线路径;当机器人[1]的尺寸远远小于管路的长度时,可将机器人[1]看成质点,假设t=t0时刻机器人[1]位于p0(x0,y0,z0),在不超过磁定位子系统位置分辨率的情况下,经过时间段Δt,Δt→0,机器人[1]移动至p1(x1,y1,z1)点;在参考移动轨迹上找一点p′1,该点为p1点在参考移动轨迹上的正交投影,计算出参考移动轨迹在p′1点切线方向的方向导数,以及由p0点指向p1点的方向导数;再计算出上述两方向导数之差,此差值即为所求的导向磁场方向修正值;最后将方向修正值转化为对应于p1点的导向磁场控制参数,并由接口电路传送至磁导向子系统[4]的电源装置[4d],使机器人[1]尽可能沿参考移动轨迹移动。6. The in vitro guidance system for micro-robots according to claim 2, characterized in that the computer control subsystem [7] controls the moving direction of the robot through the magnetic guidance algorithm as follows: First, according to the imaging subsystem [6] The generated extended image of the pipeline [2] establishes a reference trajectory of the robot [1], and selects the geometric center axis of the pipeline [2] as the reference trajectory; within the effective time of the current image, the magnetic positioning subsystem [5] is measured A series of discontinuous robot position coordinates are connected to obtain a polyline path; when the size of the robot [1] is much smaller than the length of the pipeline, the robot [1] can be regarded as a particle, assuming that at t=t 0 , the robot [ 1] located at p 0 (x 0 , y 0 , z 0 ), without exceeding the position resolution of the magnetic positioning subsystem, the robot [1] moves to p 1 (x 1 , y 1 , z 1 ) point; find a point p′ 1 on the reference moving track, which is the orthogonal projection of point p 1 on the reference moving track, and calculate the direction of the reference moving track in the tangential direction of point p′ 1 Derivative, and the directional derivative from point p 0 to point p 1 ; then calculate the difference between the above two direction derivatives, this difference is the correction value of the direction of the steering magnetic field; finally convert the direction correction value to correspond to p 1 Point guidance magnetic field control parameters are transmitted by the interface circuit to the power supply unit [4d] of the magnetic guidance subsystem [4], so that the robot [1] can move along the reference trajectory as much as possible.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015529471A (en) * 2012-06-13 2015-10-08 コーポレイション ドゥレ エコール ポリテクニーク ドゥ モンレアル Grouping and control of magnetic sensors

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009009616A1 (en) * 2009-02-19 2010-08-26 Siemens Aktiengesellschaft Endoscopic capsule with device for promoting movement in the case of movement-inhibiting edge friction
US8777947B2 (en) * 2010-03-19 2014-07-15 Smith & Nephew, Inc. Telescoping IM nail and actuating mechanism
US20140039314A1 (en) * 2010-11-11 2014-02-06 The Johns Hopkins University Remote Center of Motion Robot for Medical Image Scanning and Image-Guided Targeting
US10102334B2 (en) * 2010-12-30 2018-10-16 Given Imaging Ltd. System and method for automatic navigation of a capsule based on image stream captured in-vivo
CN102048517B (en) * 2011-01-05 2012-05-30 华南理工大学 Screw-type active-thrust capsule-like robot
CN103121212B (en) * 2011-11-18 2016-08-03 同济大学 The microrobot driven based on antibacterial
CN103222842B (en) * 2013-04-18 2015-09-09 安翰光电技术(武汉)有限公司 A kind of device and method controlling capsule endoscope and move at human body alimentary canal
EP3033034B1 (en) 2013-08-15 2021-07-07 Intuitive Surgical Operations, Inc. Instrument sterile adapter drive interface
EP3708105B1 (en) 2013-08-15 2022-02-09 Intuitive Surgical Operations, Inc. Preloaded surgical instrument interface
JP6719376B2 (en) * 2013-08-15 2020-07-08 インテュイティブ サージカル オペレーションズ, インコーポレイテッド Driven elements of robot equipment
EP3834763A1 (en) 2014-08-15 2021-06-16 Intuitive Surgical Operations, Inc. A surgical system with variable entry guide configurations
CN104434008B (en) * 2014-12-12 2016-09-21 北京大学第三医院 Endoscope robot
CN105045261B (en) * 2015-06-19 2018-07-20 台州开腾园林工程有限公司 The steering control system of miniature untethered travel robot
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CN109746909A (en) * 2017-11-08 2019-05-14 深圳先进技术研究院 A kind of robot motion control method and equipment
CN109330684A (en) * 2018-10-16 2019-02-15 日照市以恒信息技术有限公司 A kind of magnetic navigation device and magnetic navigation method for cerebrovascular interventional therapy
US11521307B2 (en) * 2018-12-17 2022-12-06 ETH Zürich Method and system for propelling and controlling displacement of a microrobot in a space having a wall
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CN110327016A (en) * 2019-06-11 2019-10-15 清华大学 Intelligent minimally invasive diagnosis and treatment integral system based on optical image and optical therapeutic
CN112438804B (en) * 2019-08-28 2024-06-14 湖南早晨纳米机器人有限公司 Control system and control method of nano robot
CN112438803B (en) * 2019-08-28 2024-06-14 湖南早晨纳米机器人有限公司 Control system and control method of micro-nano robot
CN111419239B (en) * 2020-04-15 2023-01-24 江苏食品药品职业技术学院 A blood amino acid and carnitine quantitative detection device based on electromagnetic control
CN112828877B (en) * 2020-12-31 2022-03-11 华中科技大学 Driving device of electromagnetic driving type magnetic soft robot
CN112785648B (en) * 2021-04-12 2021-07-06 成都新西旺自动化科技有限公司 Visual alignment method, device and equipment based on to-be-imaged area and storage medium
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5337732A (en) * 1992-09-16 1994-08-16 Cedars-Sinai Medical Center Robotic endoscopy
US5662587A (en) * 1992-09-16 1997-09-02 Cedars Sinai Medical Center Robotic endoscopy
US5906591A (en) * 1996-10-22 1999-05-25 Scuola Superiore Di Studi Universitari E Di Perfezionamento S. Anna Endoscopic robot
CN1718152A (en) * 2005-06-29 2006-01-11 中国科学院合肥物质科学研究院 External magnetic field driving device and method for in-vivo detector

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5337732A (en) * 1992-09-16 1994-08-16 Cedars-Sinai Medical Center Robotic endoscopy
US5662587A (en) * 1992-09-16 1997-09-02 Cedars Sinai Medical Center Robotic endoscopy
US5906591A (en) * 1996-10-22 1999-05-25 Scuola Superiore Di Studi Universitari E Di Perfezionamento S. Anna Endoscopic robot
CN1718152A (en) * 2005-06-29 2006-01-11 中国科学院合肥物质科学研究院 External magnetic field driving device and method for in-vivo detector

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015529471A (en) * 2012-06-13 2015-10-08 コーポレイション ドゥレ エコール ポリテクニーク ドゥ モンレアル Grouping and control of magnetic sensors
EP2861174A4 (en) * 2012-06-13 2016-03-16 Polyvalor Ltd Partnership AGGREGATION AND CONTROL OF MAGNETO-SENSITIVE ENTITIES
US9905347B2 (en) 2012-06-13 2018-02-27 Polyvalor, Limited Partnership Aggregation and control of magneto-responsive entities
US10446308B2 (en) 2012-06-13 2019-10-15 Polyvalor, Limited Partnership Aggregation and control of magneto-responsive entities

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