CN100487753C - CO for simulating human body tepidity2Pneumoperitoneum experimental device - Google Patents
CO for simulating human body tepidity2Pneumoperitoneum experimental device Download PDFInfo
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Abstract
一种模拟人体温热CO2气腹的实验装置,属医学实验装置技术领域。欲获得满足系统全面的温热CO2气腹研究需要的实验装置。本发明的其特点是容量和人体腹腔可比拟的气腹箱,是一个由绝热树脂材料构成的空芯六面体,箱壁外侧由内向外依次密封覆盖有铝箔,绕有加热电阻丝的石棉加热带,外层裹有软性绝热泡沫构成的保温套;有三个与气腹箱相通的管子,一个向上的通管为进气管,与热湿CO2发生器的出口相连接,另二个各为向上,和向下的,各带控制阀的通管。热湿CO2发生器由CO2加热器、雾化器和混合器构成。实施本发明后,提供了一种CO2的温度、湿度、流量和压力等可以控制的人体热CO2气腹模拟实验装置,可以在体外最大程度地模拟人体气腹情况,在明确温度场分布的基础上完成温热CO2气腹的系统研究。
The invention relates to an experimental device for simulating human body temperature CO2 pneumoperitoneum, which belongs to the technical field of medical experimental devices. To obtain an experimental device that meets the needs of systematic and comprehensive warm CO 2 pneumoperitoneum research. The characteristic of the present invention is that the gas-peritoneum box with a capacity comparable to the abdominal cavity of a human body is a hollow hexahedron made of heat-insulating resin material, and the outer side of the box wall is sealed and covered with aluminum foil from the inside to the outside, and an asbestos heating belt wrapped with a heating resistance wire , the outer layer is wrapped with an insulating cover made of soft heat-insulating foam; there are three pipes connected with the gas abdomen box, one upward pipe is the air intake pipe, which is connected with the outlet of the hot and humid CO 2 generator, and the other two are respectively Up, and down, each with a control valve through the pipe. The hot and humid CO2 generator consists of a CO2 heater, atomizer and mixer. After the present invention is implemented, a human body thermal CO pneumoperitoneum simulation experiment device that can control the temperature, humidity, flow and pressure of CO is provided, which can simulate the pneumoperitoneum situation of the human body to the greatest extent in vitro, and can clearly define the temperature field distribution. On the basis of completing the systematic study of warm CO 2 pneumoperitoneum.
Description
技术领域 technical field
属医学实验装置技术,是涉及模拟人体温热CO2气腹的实验装置。It belongs to medical experiment device technology, and is an experiment device involving simulating human body heat CO2 pneumoperitoneum.
背景技术 Background technique
微创外科是现代外科的发展方向,腹腔镜技术是其代表技术。作为腹腔镜手术基础的CO2气腹一直以来是腹腔镜技术研究的焦点。常规气腹应用的主要是常温CO2(室温25℃),其应用安全性等已得到系统研究。但是,常温CO2气体存在许多不足,可引起体核温度下降导致应激反应,影响患者术后恢复,并且随着腹腔镜运用于恶性肿瘤手术等长时间手术而问题益加突出,此外,还可引起腹部及肩部术后疼痛,心动过速等术后不适。随着腹腔镜技术的不断进步和日益完善,温CO2气腹(35-37℃)日渐应用于临床。尽管已有临床应用,但是温CO2的相关系统研究却严重不足。临床研究报道不一,基础研究则相当缺乏,气体温度在腹腔内的分布不明,腹腔镜恶性肿瘤手术中温CO2是否会增加肿瘤细胞播散等重要问题都少有研究,除温CO2缺乏研究以外,更高温度的CO2,即热CO2(41-43℃)在腹腔镜恶性肿瘤手术中是否具有杀伤肿瘤细胞组织,阻断肿瘤细胞播散,从而能够防治腹膜种植转移等值得探讨。总的来说,温热CO2气腹缺乏系统全面的研究和探讨,而研究缺乏的最主要原因是缺乏良好的人体温热CO2气腹模拟实验装置。Minimally invasive surgery is the development direction of modern surgery, and laparoscopy is its representative technology. As the basis of laparoscopic surgery, CO2 pneumoperitoneum has always been the focus of laparoscopic technology research. Normal temperature CO 2 (
目前,该类系统完整的实验装置尚缺乏。已报道的相关装置主要是通过CO2加热加湿恒温装置连接简易气腹模拟设备来实现。其中CO2的加热加湿及恒温目前主要通过以下三种方式实现:①具有内置加热功能的气腹机接上加湿装置:如Stryker气腹机加湿器;②不具有内置加热功能的气腹机接加热加湿装置:如简易Stryker气腹机+Insufflow热湿管;③使用既能加热又能加湿的气腹机,如Smith&Nephew气腹机;简易气腹模拟设备则国外报道或模糊不清,或过于简单。这些实验装置归结起来存在如下问题:①加热最高只能达到41℃,无法达到热CO2研究所需的41℃以上的温度;②温热CO2气体在一定空间内的温度分布常常是不均的,不同的部位有着不同的温度,空间较大时,温度差可以很大。而目前的实验装置,不论那种加热加湿方式,其测量的温度湿度都是仪器的气体出口温度,且温度湿度探头为单探头,不能自由移动,不能置入气腹模拟设备中测量气腹中特定部位的实际温度,因而虽然有恒温调节装置和调节能力,但是由于探头固定而只能保证仪器气体出口的气体温度湿度,不能保证气腹内特定部位的温度和湿度;③气腹模拟设备不足:缺乏相应的匹配良好的气腹模拟设备,气腹模拟装置结构简单导致气腹模拟失真,如人体腹壁温度缺乏模拟、容积不符合人体实际气腹的容量等,压力流量等研究因素的控制不足,温热CO2气体的温度分布不明等等。总起来说,目前的实验装置无法满足系统全面的温热CO2气腹研究的需要,缺乏良好的模拟人体温热CO2气腹的实验装置。At present, a complete experimental device for this type of system is still lacking. The related devices that have been reported are mainly realized by connecting simple pneumoperitoneum simulation equipment through CO2 heating, humidification and constant temperature device. Among them, the heating, humidification and constant temperature of CO 2 are mainly realized through the following three methods: ①The insufflation machine with built-in heating function is connected to the humidification device: such as the Stryker insufflation machine Humidifier; ②The insufflation machine without built-in heating function is connected to the heating and humidifying device: such as a simple Stryker insufflation machine + Insufflow heat and humidity tube; ③Use an insufflation machine that can both heat and humidify, such as Smith&Nephew insufflation machine; simple Foreign reports on pneumoperitoneum simulation equipment are either vague or too simple. These experimental devices have the following problems: ①The heating can only reach a maximum of 41°C, which cannot reach the temperature above 41°C required for hot CO 2 research; ②The temperature distribution of warm CO 2 gas in a certain space is often uneven Yes, different parts have different temperatures, and when the space is large, the temperature difference can be large. However, the current experimental device, regardless of the heating and humidification method, measures the temperature and humidity at the gas outlet temperature of the instrument, and the temperature and humidity probe is a single probe, which cannot move freely, and cannot be placed in the pneumoperitoneum simulation equipment to measure the pneumoperitoneum. The actual temperature of a specific part, so although there is a constant temperature adjustment device and adjustment ability, but because the probe is fixed, only the gas temperature and humidity at the gas outlet of the instrument can be guaranteed, and the temperature and humidity of a specific part in the pneumoperitoneum cannot be guaranteed; ③ Insufficient pneumoperitoneum simulation equipment : Lack of corresponding well-matched pneumoperitoneum simulation equipment, simple structure of pneumoperitoneum simulation device leads to pneumoperitoneum simulation distortion, such as lack of simulation of human abdominal wall temperature, volume does not conform to the actual pneumoperitoneum capacity of human body, etc., insufficient control of research factors such as pressure and flow , the temperature distribution of warm CO2 gas is unknown, etc. Generally speaking, the current experimental devices cannot meet the needs of systematic and comprehensive warm CO2 pneumoperitoneum research, and there is a lack of good experimental devices for simulating human warm CO2 pneumoperitoneum.
发明内容 Contents of the invention
本发明提供可将CO2气体加热加湿到指定温度和湿度并保持恒定,输入容量、压力等与人体气腹可比拟的气腹箱,箱内探头可预先设定,能实现温热CO2气腹良好模拟并用于系统研究的一种模拟人体温热CO2气腹的实验装置。The invention provides an insufflation box that can heat and humidify CO2 gas to a specified temperature and humidity and keep it constant. The input capacity and pressure are comparable to those of human pneumoperitoneum. The probes in the box can be preset to realize warming of CO2 gas An experimental device that simulates the human body's warm CO 2 pneumoperitoneum, which is well simulated and used for system research.
本发明的技术方案是:Technical scheme of the present invention is:
一种模拟人体温热CO2气腹的实验装置,由医用CO2钢瓶出口与气体减压阀进口相接;CO2流量计串接在热湿CO2发生器的进口与减压阀的出口之间,热湿CO2发生器的出口与气腹箱进口相连;并有恒温恒湿检测、控制装置引出检测端和控制端;检测端有气腹箱内的温湿探头、箱壁温度探头以及热湿CO2发生器的雾化器部分的汽雾温度探头;控制端有热湿CO2发生器的CO2加热和雾化液加热控制端、箱体加热控制端以及超声振子控制端相连接所组成;其特征是:容量和人体腹腔可比拟的气腹箱是一个由绝热树脂材料构成的空芯六面体,箱壁外侧由内向外依次紧密覆盖有铝箔,绕有加热电阻丝的石棉加热带,外层裹有软性绝热泡沫构成的保温套;有三个与气腹箱相通的管子;一个为向上的进气通管,与热湿CO2发生器的混合器部分(混合器)的出口相接,混合器的一个入口端与CO2加热器的出口端相接,混合器的另一入口端与热湿雾化器的出口端相接;另二个通管,一个带有控制阀的位于顶部向上与进气口并列的出气口通管,另一个处在底部向下带控制阀的出气口通管;CO2加热器是一个圆柱体内腔,中心有垂直腔底的固定电加热柱,加热片呈螺旋状盘绕其上形成类似钻头状结构,外紧密包被不锈钢套,形成螺旋加热气道,加热柱加热并传热至螺旋加热片及包被钢套,气体通过螺旋气道时三者共同对其加热;雾化器是一个装水的密闭容器,在水的上方有通外的管口,在箱体的中下部的水中,各有带控制的加热体和超声振子;混合器是有一根粗管,在粗管壁上有一开口,从开口处顺粗管延伸方向,平行插入一口径渐小的渐细管,在粗管中心处折弯,与粗管壁平行,细管口处在粗管的管内中心;与粗管壁垂直伸出的细管以及粗管外壁表面均覆裹绝热层;伸出粗管壁的细管口与CO2加热器出口相接,粗管入口接雾化器出口,粗管出口接气腹箱入口。An experimental device for simulating human body temperature CO2 pneumoperitoneum, the outlet of the medical CO2 cylinder is connected to the inlet of the gas pressure reducing valve; the CO2 flowmeter is connected in series between the inlet of the hot and humid CO2 generator and the outlet of the pressure reducing valve Between, the outlet of the hot-humid CO2 generator is connected with the inlet of the insufflation box; and there are constant temperature and humidity detection and control devices leading to the detection end and the control end; And the vapor mist temperature probe of the atomizer part of the hot and humid CO2 generator; the control end has the CO2 heating of the hot and humid CO2 generator and the atomized liquid heating control end, the box heating control end and the ultrasonic vibrator control end. It is composed of connections; its characteristics are: the gas abdomen box with a capacity comparable to the human abdominal cavity is a hollow hexahedron made of heat-insulating resin material, the outside of the box wall is tightly covered with aluminum foil from inside to outside, and asbestos heating with heating resistance wire Belt, the outer layer is wrapped with a thermal insulation cover made of soft thermal insulation foam; there are three pipes communicating with the gas abdomen box; one is the upward air intake pipe, which is connected to the mixer part (mixer) of the hot and humid CO 2 generator The outlets are connected, one inlet end of the mixer is connected with the outlet end of the CO2 heater, the other inlet end of the mixer is connected with the outlet end of the hot and humid atomizer; the other two through pipes, one with a control The valve is located at the top of the gas outlet pipe parallel to the air inlet, and the other is at the bottom with the gas outlet pipe with the control valve; The heating column, the heating sheet is coiled in a spiral shape to form a drill-like structure, and is tightly covered with a stainless steel sleeve to form a spiral heating air channel. The heating column is heated and transferred to the spiral heating sheet and the coated steel sleeve, and the gas passes through the spiral gas The three together heat it; the atomizer is a closed container filled with water, above the water there is a nozzle leading to the outside, and in the water in the middle and lower part of the box, each has a controlled heating body and an ultrasonic vibrator. The mixer has a thick tube with an opening on the wall of the thick tube. From the opening along the direction of the extension of the thick tube, a tapered tube with a smaller diameter is inserted in parallel, bent at the center of the thick tube, and parallel to the wall of the thick tube. , the thin tube opening is located in the center of the thick tube; the thin tube extending perpendicular to the thick tube wall and the outer wall of the thick tube are covered with an insulating layer; the thin tube opening protruding from the thick tube wall is connected to the outlet of the CO2 heater , the inlet of the thick tube is connected to the outlet of the nebulizer, and the outlet of the thick tube is connected to the inlet of the insufflation box.
实施本发明后的积极效果是提供了一种CO2的温度、湿度、流量和压力等可以控制的人体温热CO2气腹模拟实验装置,可以在体外最大程度地模拟人体温热气腹,在明确温度场分布的基础上完成温热CO2气腹的系统研究。此外,本实验装置还可广泛应用于常温CO2以及其他不同种类气体的医学研究,稍作变更也可供临床手术应用。The positive effect after implementing the present invention is to provide a kind of CO temperature, humidity, flow rate and pressure etc. can control the body temperature CO pneumoperitoneum simulation experiment device, can simulate the human body heat pneumoperitoneum to the greatest extent outside the body, in The systematic study of warm CO2 pneumoperitoneum was completed on the basis of clarifying the temperature field distribution. In addition, this experimental device can also be widely used in the medical research of normal temperature CO2 and other different kinds of gases, and it can also be used in clinical operations with slight changes.
附图说明 Description of drawings
图1,本发明的系统结构示意图Fig. 1, the system structure schematic diagram of the present invention
图2,模拟人体腹腔的气腹箱结构示意图Figure 2. Schematic diagram of the structure of the gas-peritoneum box that simulates the human abdominal cavity
图3,,热湿CO2发生器结构示意图Fig. 3, Schematic diagram of the structure of the hot and humid CO2 generator
图4,,混合器原理示意图Figure 4, Schematic diagram of the mixer principle
具体实施方式 Detailed ways
现结合附图对本发明作进一步说明The present invention will be further described now in conjunction with accompanying drawing
一种模拟人体温热CO2气腹的实验装置,由医用CO2钢瓶5出口与气体减压阀4进口相接;CO2流量计3串接在热湿CO2发生器2的进口20与减压阀4的出口之间,热湿CO2发生器2的出口与气腹箱6进口相连;并有恒温恒湿检测、控制装置1引出检测端和控制端;检测端有气腹箱内的温湿探头15、箱壁温度探头7以及热湿CO2发生器2的雾化器部分的汽雾温度探头32;控制端有热湿CO2发生器2的CO2加热和雾化液加热控制端、箱体加热控制端以及超声振子30控制端相连接所组成;其特征是:容量和人体腹腔可比拟的气腹箱6是一个由绝热树脂材料构成的空芯六面体,箱壁外侧由内向外依次紧密覆盖有铝箔,绕有加热电阻丝13的石棉加热带,外层裹有软性绝热泡沫构成的保温套;有三个与气腹箱6相通的管子;一个为向上的进气通管10,与热湿CO2发生器的混合器部分(混合器)26的出口相接,混合器26的一个入口端与CO2加热器19的出口端相接,混合器的另一入口端与热湿CO2发生器的雾化器28的出口端相接;另二个通管,一个带有控制阀8的位于顶部向上与进气口并列的出气口通管9,另一个处在底部向下带控制阀18的出气口通管17;CO2加热器19是一个圆柱体内腔,中心有垂直腔底的固定电加热柱24,加热片22呈螺旋状盘绕其上,形成类似钻头状结构,外紧密包被不锈钢套23,形成螺旋加热气道,加热柱加热并传热至螺旋加热片及包被钢套,气体通过螺旋气道时三者共同对其加热;雾化器28是一个装水29的密闭容器,在水的上方有通外的管口,在箱体的中下部的水中,各有带控制的加热体31和超声振子30;混合器26是有一根粗管35,在粗管壁上有一开口,从开口处顺粗管延伸方向,平行插入一口径渐小的渐细管,在粗管中心处折弯,与粗管壁平行,细管口34处在粗管的管内中心;与粗管壁垂直伸出的细管以及粗管外壁表面均覆裹绝热层33;伸出粗管壁的细管口与CO2加热器出口相接,粗管入口接雾化器出口,粗管出口接气腹箱入口。An experimental device for simulating human body temperature CO2 pneumoperitoneum, the medical CO2 steel cylinder 5 outlet is connected to the gas pressure reducing valve 4 inlet; the CO2 flow meter 3 is connected in series to the
其中11为气腹箱保温套;12为气腹箱壁;14为带探头的压力表;16医学实验对象载体;17下出气口;21加热器保温套;27混合气道;32汽雾温度探头。Among them, 11 is the insulation cover of the pneumoperitoneum box; 12 is the wall of the pneumoperitoneum box; 14 is the pressure gauge with a probe; 16 is the carrier of the medical experiment object; 17 is the lower air outlet; 21 is the heat insulation cover of the heater; probe.
现对混合器原理作一说明:Now explain the principle of the mixer:
当CO2从口20进入加热器19后,热CO2进入混合器26的细管,通过口径渐小的渐细管25,CO2气高速由管25喷向粗管35的内管,并把汽雾吸入混合气道27,汽雾与CO2气体均匀混合。When CO enters the
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CN103021249B (en) * | 2012-12-31 | 2015-02-04 | 东莞市人民医院 | Heating carbon dioxide simulation abdominal cavity experimental box |
CN108685607B (en) * | 2018-06-15 | 2024-02-02 | 首都医科大学附属北京世纪坛医院 | Special constant temperature pneumoperitoneum system of tumour surgery |
CN109864765A (en) * | 2019-01-25 | 2019-06-11 | 中国人民解放军陆军军医大学第一附属医院 | Pneumoperitoneum apparatus device is used in a kind of laparoscopy |
CN111184543B (en) * | 2019-05-31 | 2024-10-25 | 上海交通大学医学院附属瑞金医院 | Multifunctional laparoscopic surgery auxiliary system |
CN114176665B (en) * | 2021-12-28 | 2024-01-23 | 上海交通大学 | Temperature-control humidifying pneumoperitoneum device for laparoscopic surgery |
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WO1994001154A1 (en) * | 1992-07-07 | 1994-01-20 | Andronic Devices, Ltd. | Apparatus and method for improved insufflation |
JP4154093B2 (en) * | 1999-09-13 | 2008-09-24 | キヤノン株式会社 | Dry toner and image forming method |
CN200972473Y (en) * | 2006-11-14 | 2007-11-07 | 上海交通大学医学院附属瑞金医院 | CO for simulating human body tepidity2Pneumoperitoneum experimental device |
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