Summary of the invention:
The objective of the invention is to: a kind of medicine for the treatment of stomachache and preparation method thereof is provided, and the medicine that is provided is a pure natural medical, has no side effect, and does not produce drug resistance, and the cure rate height, is difficult for recurrence, and therapeutic effect is good.
The present invention is achieved in that according to components by weight percent and calculates: it is prepared from for 200~400 parts by 300~700 parts of Herba Taraxacis, 300~700 parts of Flos Loniceraes, 300~700 parts of Herba Paederiaes, 300~700 parts of Rhizoma Corydalis, 300~700 parts of Endothelium Corneum Gigeriae Galli, 200~400 parts of Rhizoma Acori Graminei, 200~400 parts of Saussurea lappa Clarke, 200~400 parts of Fructus Evodiaes, 200~400 parts of Fructus Aurantiis and Radix Et Rhizoma Rhei.
Say accurately, calculate according to weight: it is prepared from by Herba Taraxaci 500g, Flos Lonicerae 500g, Herba Paederiae 500g, Rhizoma Corydalis 500g, Endothelium Corneum Gigeriae Galli 500g, Rhizoma Acori Graminei 250g, Saussurea lappa Clarke 250g, Fructus Evodiae 250g, Fructus Aurantii 250g and Radix Et Rhizoma Rhei 250g.
The medicine that the present invention treats stomachache is preparation like this: take by weighing Herba Taraxaci 500g, Flos Lonicerae 500g, Herba Paederiae 500g, Rhizoma Corydalis 500g, Endothelium Corneum Gigeriae Galli 500g, Rhizoma Acori Graminei 250g, Saussurea lappa Clarke 250g, Fructus Evodiae 250g, Fructus Aurantii 250g and Radix Et Rhizoma Rhei 250g, mix, grind to form fine powder and get final product.
The medicine that the present invention treats stomachache can also prepare like this: take by weighing Herba Taraxaci, Flos Lonicerae, Herba Paederiae, Rhizoma Corydalis, Endothelium Corneum Gigeriae Galli, Rhizoma Acori Graminei, Saussurea lappa Clarke, Fructus Evodiae, Fructus Aurantii and Radix Et Rhizoma Rhei, the decocting that adds 3~7 times of amount medical materials boils 2~6 times, each 1~4 hour, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, promptly obtain the effective ingredient of medicine of the present invention, the effective ingredient that obtains is added the adjuvant that needs, is prepared into required preparation according to conventional method.
The tablet that the present invention treats the medicine of stomachache prepares like this: take by weighing Herba Taraxaci 500g, Flos Lonicerae 500g, Herba Paederiae 500g, Rhizoma Corydalis 500g, Endothelium Corneum Gigeriae Galli 500g, Rhizoma Acori Graminei 250g, Saussurea lappa Clarke 250g, Fructus Evodiae 250g, Fructus Aurantii 250g and Radix Et Rhizoma Rhei 250g, the decocting that adds 5 times of amount medical materials boils 3 times, each 1.5 hours, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, adds appropriate amount of auxiliary materials lactose and dextrin, mixing, granulate, drying, tabletting, promptly.
The capsule that the present invention treats the medicine of stomachache prepares like this: take by weighing Herba Taraxaci 300g, Flos Lonicerae 300g, Herba Paederiae 300g, Rhizoma Corydalis 300g, Endothelium Corneum Gigeriae Galli 300g, Rhizoma Acori Graminei 200g, Saussurea lappa Clarke 200g, Fructus Evodiae 200g, Fructus Aurantii 200g and Radix Et Rhizoma Rhei 200g, the decocting that adds 3 times of amount medical materials boils 2 times, each 4 hours, collecting decoction filtered, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, mixing, encapsulated, promptly.
The granule that the present invention treats the medicine of stomachache prepares like this: take by weighing Herba Taraxaci 700g, Flos Lonicerae 700g, Herba Paederiae 700g, Rhizoma Corydalis 700g, Endothelium Corneum Gigeriae Galli 700g, Rhizoma Acori Graminei 400g, Saussurea lappa Clarke 400g, Fructus Evodiae 400g, Fructus Aurantii 400g and Radix Et Rhizoma Rhei 400g, the decocting that adds 7 times of amount medical materials boils 6 times, each 1 hour, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, add aspartame then and lactose is an amount of, dry-pressing is granulated promptly.
The soft capsule preparation that the present invention treats the medicine of stomachache prepares like this: take by weighing Herba Taraxaci 400g, Flos Lonicerae 400g, Herba Paederiae 400g, Rhizoma Corydalis 400g, Endothelium Corneum Gigeriae Galli 400g, Rhizoma Acori Graminei 300g, Saussurea lappa Clarke 300g, Fructus Evodiae 300g, Fructus Aurantii 300g and Radix Et Rhizoma Rhei 300g, the decocting that adds 4 times of amount medical materials boils 3 times, each 2 hours, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, add tween 80 and propylene glycol then, mixing is with being pressed into soft capsule after the colloid mill grinding, promptly.
The traditional Chinese medical science is thought: the reason that stomachache takes place is owing to troubled thoughts brain anger, the irritability imbalance, and perverse and unreasonable manner is violated stomach; Or the dysfunction of the spleen, stomach-QI being unable to descend normally and causing.Be monarch drug with Flos Lonicerae, Herba Taraxaci among the we, get the merit of its pathogenic fire purging heat-clearing and toxic substances removing.Flos Lonicerae, the flower of just opening for dry flower or the band of caprifoliaceae plant Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae or hair style Radix Ophiopogonis.The flowers are in blossom gathers drying before putting for early summer; It is cold in nature, sweet in the mouth.Effect with heat-clearing and toxic substances removing, wind-heat dissipating, the treatment that is mainly used in carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating disease.Herba Taraxaci is for feverfew Herba Taraxaci, alkali ground Herba Taraxaci or belong to the dry herbs of several plants together.Spend spring to autumn when just opening and excavate, remove impurity, clean, dry.Nature and flavor hardship, sweet, cold.Return liver, stomach warp.Have heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effect of inducing diuresis for treating stranguria syndrome is used for furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the treatment of the puckery pain of pyretic stranguria.Modern pharmacological research shows that two medicines all have antibacterial action, and gastric ulcer is had preventive effect, and " book on Chinese herbal medicine is logical upright " cloud: Flos Lonicerae master distension, " book on Chinese herbal medicine just " cloud: Flos Lonicerae is good at removing toxic substances.Herba Taraxaci is traditional affectionate antidote, by research in recent years, proves that it has tangible anti-infectious function, is used for various inflammation, and the inflammation to stomach also has the good curing effect certainly.Herba Paederiae, Rhizoma Corydalis are ministerial drug in the side, and the pharmacological research of two flavor medicines through the modern times all has similar morphine, and dolantin etc. are analgesic activity preferably, energy analgesic antidotal, dyspepsia and intestinal stasis relieving." medical science is seen the source " cloud: Rhizoma Corydalis is controlled depressed the stagnating of taste and is not loose, cardiac and abdominal pain, and the therapeutic method to keep the adverse QI flowing downwards helps digestion.With Endothelium Corneum Gigeriae Galli, Rhizoma Acori Graminei is assistant, all has the increase gastric secretion behind the two medicines clothes, and removing food stagnancy stagnates, strengthening the spleen and stomach, and the distension that helps digestion, gastrointestinal abnormal fermentation is prevented in vomiting, the effect of the slow smooth muscle spasm of speeding.For making, reach soothing the liverly with the Radix Aucklandiae, Fructus Aurantii, Radix Et Rhizoma Rhei, regulate the flow of vital energy, rush down the merit of down blow detoxifcation.All medicines match, and are total to the long memorial liver and qi, the effect of heat-clearing and toxic substances removing, analgesia, the logical invigorating middle warmer of temperature, invigorating the spleen and regulating the stomach.Thereby can receive good effect to the treatment of gastropathy.
The applicant is through the clinical practice of four more than ten years, and the diagnosis and treatment tens thousand of examples of disease of having a stomachache are cured thousands of examples with medicine of the present invention, have received excellent curative, and it is as follows now to enumerate ten routine clinical cases:
Example one: the king so-and-so, man, 45 years old, peasant.On March 5th, 1963 went to a doctor.Gastral cavilty portion pain has had several years, increases the weight of whenever spring, two seasons of autumn, suppresses bloated, heating installation, heartburn, pantothenic acid during usual sick sending out, and vomiting recently is frequent, and thing does not feel like eating.
Main suit: buy several gastropines when pain, pantothenic acid usually and eat, with alleviating pain, but do not have therapeutical effect, thereby the state of an illness increases the weight of year by year at all.
Health check-up: chronic facies, lassitude, nutrition is very poor, stringy and thready pulse.Examine through so-and-so x of hospital line canel barium meal contrast examination and to be duodenal bulbar ulcer.
Treatment: after taking one week of medicine of the present invention (10g*7 bag 1 bag), pain obviously alleviates, take 7 week of this medicine (1 bag of 10g*7 bag) continuously after, symptom all disappears, diet heightens.June, stomach and duodenography there is no pathological changes in so-and-so hospital's review result.So far do not recur.
Example two: the hole so-and-so, the man, 35 years old, the carpenter, JIUYUE in 1972 was gone to a doctor on the 8th.
The main suit: the stomachache history is arranged more than a year, must eat slightly and subtract,, also vomit when pain is acute with Yuan gas acid regurgitation, system of mourning acids medicine, pain reduces to some extent.Through so-and-so hospital's gastrointestinal canel barium meal contrast examination, the visible ulcer niche of lesser gastric curvature side has obvious tenderness, and peristalsis is not obvious at this, examines to be gastric ulcer.
Treatment: after taking medicine of the present invention fortnight (two bags of 10g*7 bags), pain disappears substantially.Both tea-drinking was worked as with medicine 10g bubble boiled water of the present invention every day in the back, and continuous two months, three never suffered from the disease that has a stomach-ache during the last ten years so far.
Example three: thunder so-and-so, the woman, 30 years old, the peasant went to a doctor in August, 1976.
Ill process: over the past half year, variable interval stomachache, heartburn is diagnosed as superficial gastritis through so-and-so hospital gastroscope inspection.
Health check-up: chronic facies, complexion is wax yellow, and nutrition is not good enough, thready and rapid pulse, thin white fur of tongue.
Treatment: through taking medicine of the present invention 7 days (10g*7 bag 1 bag), and advise it not eat raw food, acid, peppery thing at period in a medicine, pain relief, continue to take 28 days after, through the examination in hospital recovery from illness, and recurrence as yet so far.
Example four: Zhang, man, 32 years old.
The main suit: often stomachache, the pain increased when drinking, eating hard thing or vinegar-pepper food, often with the heating installation acid regurgitation, eat sweet wine or white gruel after acid more frequently, to the gastroscopy of the x of hospital light, clarifying a diagnosis is gastric ulcer.
Treatment: symptom disappears substantially after taking 8 bags of medicines of the present invention (10g*7 bag be a bag), after take 5 bags again and consolidate curative effect, by after the taking medicine of continuous three wheat harvesting periods, the patient removes examination in hospital after half a year, ulcer healing.Follow up a case by regular visits to not recurrence as yet so far.
Example five: Liu so-and-so, the man, 31 years old is gastric ulcer at examination in hospital, after taking 14 days medicines of the present invention, stomachache obviously alleviates.This person is because of being addicted to drink, because of insobriety recurs again, after one bag of " Guizhou stomach medicine " 7 sack of 10g*7 bag of asking someone to take obeyed altogether 49 days, after the alleviating alcohol addiction, do not send out in 3 years so far.
Example six: the king so-and-so, the man, 40 years old, because of long-term gastralgia, go to so-and-so hospital to make x line and gastroscopy and canel barium meal contrast examination, pyloric cap has obvious niche, is diagnosed as duodenal bulbar ulcer.Amount to 21 days for three bags through obeying medicine of the present invention (10g*7 bag be a bag), the patient feels that symptom takes a turn for the better to some extent, again the bimester taking continuously after, the patient is perfectly recovered from one's illness, and does not see recurrence so far.
Example six: solemn so-and-so, woman, 41 years old, peasant.The gastral cavilty distending pain is shown effect repeatedly, loss of appetite, and limbs fatigue is an atrophic gastritis in so-and-so hospital gastroscope inspection.
During prescription on individual diagnosis: upset in the stomach, Yuan gas pantothenic acid, dull pain or feeling of distension and oppression, massage is then relaxed, and it is shapeless to defecate, yellowish fur, small and stringy pulse.
Have a stomachache after 49 days and alleviate through obeying medicine of the present invention, but under the rib distending pain is arranged, a small amount of sour water is arranged, continue clothes after 49 days in May, 2003 check, microscopy is a chronic superficial gastritis, atrophic gastritis has obtained recovery from illness.
Example seven: Liu so-and-so, 30 years old, the teacher went to a doctor in July, 2004.
Main suit: because of diet does not have rule; the normal gastropathy of suffering from; eat irritating food or just normal gastric abscess when feeling bad; through informal dress SIDASHU, SANJIU WEITAI, bismuth aluminate compound etc., slightly alleviate during clothes, after the drug withdrawal; do not spend several days and recur again; through so-and-so hospital's tcm diagnosis is chronic gastropathy, and through obeying medicine of the present invention after 7 days, pain is promptly ended.After continued to take 49 days, the recovery from illness, so far never the recurrence.
Example eight: Song, the man, 36 years old, on January 3rd, 2005 went to a doctor.
The main suit: the x of hospital line canel barium meal contrast examination is diagnosed as duodenal bulbar ulcer, and through taking medicine of the present invention after 49 days, stomachache stops.
Example nine: Song, the man, 40 years old, went to a doctor April 4 nineteen ninety-five.
The main suit: violated gastropathy 2 years, frequent epigastric pain, the time when sending out more, it is very much serious initiating whenever spring end, autumn Mo, through so-and-so hospital's x ray examination the ulcer niche is arranged, and diagnoses duodenal bulbar ulcer.Taking 14 days left and right sides of medicine of the present invention pain disappears.
Example ten: chapter so-and-so, the woman, 18 years old, middle school student went to a doctor on May 1st, 2005.
The main suit: six kilometers in the school of leaving home, the sky did not work to get up and ate the meal meal and read to school every day, afternoon, classes are over goes back just to eat again second meal, over nearly two months, upper abdomen hits exactly the pain at any time of taking back, through take medicine of the present invention after 7 days pain stop.
Comprehensive above-mentioned clinical example, medicine of the present invention is evident in efficacy to stomachache.
Medicine of the present invention is compared with commercially available various stomach medicines, and cost is extremely low, and does not have toxicity, be difficult for producing drug resistance, and also its cure rate height, being difficult for recurrence, therapeutic effect is good, is the ideal medicament of treatment gastropathy.
The specific embodiment:
Embodiments of the invention 1: take by weighing Herba Taraxaci 500g, Flos Lonicerae 500g, Herba Paederiae 500g, Rhizoma Corydalis 500g, Endothelium Corneum Gigeriae Galli 500g, Rhizoma Acori Graminei 250g, Saussurea lappa Clarke 250g, Fructus Evodiae 250g, Fructus Aurantii 250g and Radix Et Rhizoma Rhei 250g, mix, grind to form fine powder jointly, get final product in the bag of packing into.Every bag 10g, every bag 7 bag, every day 1, bag bubble boiled water was taken, and 7 days is a course of treatment.
Embodiments of the invention 2: take by weighing Herba Taraxaci 300g, Flos Lonicerae 300g, Herba Paederiae 300g, Rhizoma Corydalis 300g, Endothelium Corneum Gigeriae Galli 300g, Rhizoma Acori Graminei 200g, Saussurea lappa Clarke 200g, Fructus Evodiae 200g, Fructus Aurantii 200g and Radix Et Rhizoma Rhei 200g, mix, grind to form fine powder jointly, get final product in the bag of packing into.
Embodiments of the invention 3: take by weighing Herba Taraxaci 700g, Flos Lonicerae 700g, Herba Paederiae 700g, Rhizoma Corydalis 700g, Endothelium Corneum Gigeriae Galli 700g, Rhizoma Acori Graminei 400g, Saussurea lappa Clarke 400g, Fructus Evodiae 400g, Fructus Aurantii 400g and Radix Et Rhizoma Rhei 400g, mix, grind to form fine powder jointly, get final product in the bag of packing into.
Embodiments of the invention 4: take by weighing Herba Taraxaci 400g, Flos Lonicerae 400g, Herba Paederiae 400g, Rhizoma Corydalis 400g, Endothelium Corneum Gigeriae Galli 400g, Rhizoma Acori Graminei 300g, Saussurea lappa Clarke 300g, Fructus Evodiae 300g, Fructus Aurantii 300g and Radix Et Rhizoma Rhei 300g, mix, grind to form fine powder jointly, get final product in the bag of packing into.
Embodiments of the invention 5: take by weighing Herba Taraxaci 500g, Flos Lonicerae 500g, Herba Paederiae 500g, Rhizoma Corydalis 500g, Endothelium Corneum Gigeriae Galli 500g, Rhizoma Acori Graminei 250g, Saussurea lappa Clarke 250g, Fructus Evodiae 250g, Fructus Aurantii 250g and Radix Et Rhizoma Rhei 250g, the decocting that adds 5 times of amount medical materials boils 3 times, each 1.5 hours, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, adds appropriate amount of auxiliary materials lactose and dextrin, mixing, granulate, drying, tabletting promptly obtains the tablet of medicine of the present invention.
Embodiments of the invention 6: take by weighing Herba Taraxaci 300g, Flos Lonicerae 300g, Herba Paederiae 300g, Rhizoma Corydalis 300g, Endothelium Corneum Gigeriae Galli 300g, Rhizoma Acori Graminei 200g, Saussurea lappa Clarke 200g, Fructus Evodiae 200g, Fructus Aurantii 200g and Radix Et Rhizoma Rhei 200g, the decocting that adds 3 times of amount medical materials boils 2 times, each 4 hours, collecting decoction filtered, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, mixing, encapsulated, promptly obtain capsule of the present invention.
Embodiments of the invention 7: take by weighing Herba Taraxaci 700g, Flos Lonicerae 700g, Herba Paederiae 700g, Rhizoma Corydalis 700g, Endothelium Corneum Gigeriae Galli 700g, Rhizoma Acori Graminei 400g, Saussurea lappa Clarke 400g, Fructus Evodiae 400g, Fructus Aurantii 400g and Radix Et Rhizoma Rhei 400g, the decocting that adds 7 times of amount medical materials boils 6 times, each 1 hour, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, add aspartame then and lactose is an amount of, dry-pressing is granulated and is promptly got granule of the present invention
Embodiments of the invention 8: take by weighing Herba Taraxaci 400g, Flos Lonicerae 400g, Herba Paederiae 400g, Rhizoma Corydalis 400g, Endothelium Corneum Gigeriae Galli 400g, Rhizoma Acori Graminei 300g, Saussurea lappa Clarke 300g, Fructus Evodiae 300g, Fructus Aurantii 300g and Radix Et Rhizoma Rhei 300g, the decocting that adds 4 times of amount medical materials boils 3 times, each 2 hours, collecting decoction, filter, the survey relative density was 1.04~1.05 clear paste when decocting liquid was concentrated into 50 ℃, drying under reduced pressure, dried cream powder is broken into fine powder, add tween 80 and propylene glycol then, mixing with being pressed into soft capsule after the colloid mill grinding, promptly obtains soft capsule preparation of the present invention.