CN100356071C - Minitype jet pump and preparation method - Google Patents
Minitype jet pump and preparation method Download PDFInfo
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Abstract
本发明提供了一种微型射流泵及其制备方法,泵体包括驱动结构和抽吸结构,驱动结构是由射流喷嘴和与之相连的驱动腔组成,驱动腔上设有驱动流体人口孔,抽吸结构包括抽吸入口端、抽吸流道和扩散出口,射流喷嘴位于扩散出口处,抽吸流道设在射流喷嘴的两侧,高压驱动气体或液体经过驱动流体人口孔进入驱动腔,在射流喷嘴出口处产生高速射流,同时在其边界处产生涡旋,涡旋卷吸抽吸流道内的流体进入射流,两种不同流速的混合流体共同流入扩散出口。微型射流泵的制备利用MEMS工艺设计,通过两张光刻版就可以实现,泵体材料的可选择范围大、易于和大多数微流体系统集成。
The invention provides a micro-jet pump and a preparation method thereof. The pump body includes a driving structure and a suction structure. The driving structure is composed of a jet nozzle and a driving chamber connected thereto. The suction structure includes a suction inlet port, a suction flow channel and a diffusion outlet. The jet nozzle is located at the diffusion outlet, and the suction flow channel is arranged on both sides of the jet nozzle. A high-speed jet is generated at the outlet of the jet nozzle, and a vortex is generated at its boundary at the same time. The vortex entrains the fluid in the suction channel into the jet, and two mixed fluids with different flow velocities flow into the diffuser outlet together. The preparation of the micro-jet pump is designed by MEMS technology, which can be realized by two photolithography plates. The pump body material has a wide range of options and is easy to integrate with most micro-fluidic systems.
Description
技术领域technical field
本发明属于微量流体控制、传输、微执行器技术领域,具体涉及一种采用微电子机械系统(MEMS)技术设计制作的微型射流泵。The invention belongs to the technical fields of microfluid control, transmission and microactuator, and in particular relates to a microjet pump designed and manufactured by adopting microelectromechanical system (MEMS) technology.
背景技术Background technique
微结构中的流体输运一直存在由于小尺寸带来的很多问题,例如微流道中液体的流动存在残余气泡,而且目前MEMS微泵因其结构复杂、加工实现难度较大,造价较高而限制了其广泛应用。Fluid transport in microstructures has always had many problems due to small size, such as residual bubbles in the flow of liquid in microchannels, and the current MEMS micropump is limited by its complex structure, difficult processing and high cost. its wide application.
微型泵是微流体控制系统的核心元件,采用MEMS技术加工的微型泵主要分为机械流体控制系统和非机械流体控制系统,机械微型泵主要包括压电微泵、电磁微泵、静电微泵和气动微泵等,这几种微泵的共同问题是结构复杂,加工实现的难度较大,制作成本相对较高,驱动需要外加复杂的电设备;非机械微泵主要包括电流体动力泵、磁流体动力泵等,这几类微泵都是用加电的方式驱动,电驱动的局限性也很明显,不能驱动非带电分子,是非均质移动,装置缺乏灵活性,进一步发展的潜力较小。且现有的很多微型泵系统的进口和出口都有可动部件(如微阀结构),这就增加了微型泵加工的难度,同时在泵的工作过程中,进出口阀极易损坏,缩短了微泵的使用寿命。一般的生物芯片都是不可重复利用的,因此以上两种微泵都因其成本较高、实现难度大,而不能在微流体芯片中广泛应用。Micropumps are the core components of microfluidic control systems. Micropumps processed with MEMS technology are mainly divided into mechanical fluid control systems and non-mechanical fluid control systems. Mechanical micropumps mainly include piezoelectric micropumps, electromagnetic micropumps, electrostatic micropumps and Pneumatic micropumps, etc., the common problems of these types of micropumps are complex structures, difficult processing and realization, relatively high production costs, and the drive requires additional complicated electrical equipment; non-mechanical micropumps mainly include electrohydrodynamic pumps, magnetic Fluid power pumps, etc. These types of micropumps are driven by electricity, and the limitations of electric drive are also obvious. They cannot drive uncharged molecules, and they move heterogeneously. The device lacks flexibility and has little potential for further development. . Moreover, the inlet and outlet of many existing micropump systems have movable parts (such as microvalve structures), which increases the difficulty of micropump processing. the service life of the micropump. General biochips are not reusable, so the above two types of micropumps cannot be widely used in microfluidic chips because of their high cost and difficulty in implementation.
发明内容Contents of the invention
本发明克服上述微型泵结构复杂、制备工艺难度大等缺点,提供了一种微型射流泵,无需外加复杂的电、磁、热等驱动系统;微型泵内没有移动部件,结构简单,适用于各种流体的微量输运。The present invention overcomes the above-mentioned shortcomings of the micro pump such as complicated structure and difficult preparation process, and provides a micro jet pump without additional complicated electric, magnetic, thermal and other driving systems; Microtransport of fluids.
本发明的另一特点在于:制备工艺容易实现, 泵体材料的可选择范围大,易于和大多数微流体系统集成。Another feature of the present invention is that the preparation process is easy to realize, the pump body material can be selected in a wide range, and it is easy to integrate with most microfluidic systems.
本发明的技术方案如下:Technical scheme of the present invention is as follows:
一种微型射流泵,泵体包括驱动结构和抽吸结构,其特征在于:驱动结构是由射流喷嘴和与之相连的驱动腔组成,抽吸结构包括抽吸入口端、抽吸流道和扩散出口,射流喷嘴位于扩散出口处,抽吸流道设在射流喷嘴的两侧,在驱动力作用下,驱动腔的射流喷嘴出口处会产生高速射流,同时在其边界处产生涡旋,涡旋卷吸抽吸流道内的流体进入射流,两种不同流速的混合流体共同流入扩散出口。A micro-jet pump, the pump body includes a driving structure and a suction structure, characterized in that: the driving structure is composed of a jet nozzle and a driving cavity connected thereto, and the suction structure includes a suction inlet port, a suction flow channel and a diffuser At the outlet, the jet nozzle is located at the diffuser outlet, and the suction flow channel is set on both sides of the jet nozzle. Under the action of the driving force, a high-speed jet will be generated at the exit of the jet nozzle of the driving chamber, and a vortex will be generated at its boundary at the same time. The fluid in the entrainment suction flow channel enters the jet flow, and two mixed fluids with different flow velocities flow into the diffusion outlet together.
所述抽吸流道是由多个相互平行的流道组成,每个流道的末端呈射流喷嘴状,流体流经流道的末端时,会在其产生的射流边界处产生涡旋,涡旋卷吸相邻流道内的流体进入射流。The suction flow channel is composed of a plurality of flow channels parallel to each other. The end of each flow channel is in the shape of a jet nozzle. When the fluid flows through the end of the flow channel, a vortex will be generated at the boundary of the jet generated by it. The vortex The swirl sucks fluid from adjacent channels into the jet.
所述抽吸入口端连接一微流体芯片。The suction inlet port is connected with a microfluidic chip.
驱动腔上设有驱动流体入口孔,高压驱动气体或液体经过驱动流体入口孔进入驱动腔,在射流喷嘴出口处产生高速射流。The driving chamber is provided with a driving fluid inlet hole, and the high-pressure driving gas or liquid enters the driving chamber through the driving fluid inlet hole, and produces a high-speed jet at the outlet of the jet nozzle.
所述驱动腔为密封腔体,通过压电、电磁、静电、形状记忆合金、指压等驱动方式产生射流。The driving cavity is a sealed cavity, and jets are generated through piezoelectric, electromagnetic, electrostatic, shape memory alloy, finger pressure and other driving methods.
一种微型射流泵的制备方法,步骤包括:A preparation method of a micro jet pump, the steps comprising:
(1)硅片上光刻、刻蚀出微型射流泵的驱动结构和抽吸结构,驱动结构包括射流喷嘴和与之相连的驱动腔,抽吸结构包括抽吸端口、抽吸流道和扩散出口;(1) The driving structure and suction structure of the micro-jet pump are photolithographically etched on the silicon chip. The driving structure includes the jet nozzle and the driving chamber connected to it. exit;
(2)采用塑料、聚合物、玻璃片或硅片作为盖片;(2) Use plastic, polymer, glass or silicon as the cover;
(3)硅片和盖片对准键合。(3) Silicon wafer and cover sheet are aligned and bonded.
一种微型泵的制备方法,步骤包括:A preparation method of a micropump, the steps comprising:
(1)制备模具,采用三维成型加工的模塑成型或真空热压法制成塑料或聚合物材料泵体结构,该结构包括微型射流泵的驱动结构和抽吸结构,驱动结构包括射流喷嘴和与之相连的驱动腔,抽吸结构包括抽吸端口、抽吸流道和扩散出口;(1) Prepare the mold, and use three-dimensional molding processing molding or vacuum hot pressing to make a plastic or polymer material pump body structure, which includes the drive structure and suction structure of the micro jet pump. The drive structure includes jet nozzles and The driving chamber connected to it, the suction structure includes a suction port, a suction flow channel and a diffusion outlet;
(2)采用塑料、聚合物、玻璃片或硅片作为盖片;(2) Use plastic, polymer, glass or silicon as the cover;
(3)将制得的塑料或聚合物泵体与盖片对准键合。(3) Align and bond the prepared plastic or polymer pump body with the cover sheet.
在盖片上光刻、刻蚀穿通孔图形,在相应的标记位置处打通孔。Lithographically and etch through-hole patterns on the cover sheet, and drill through-holes at corresponding marked positions.
在硅片上光刻、刻蚀出模具结构,采用三维成型加工的模塑成型或真空热压法制成塑料或聚合物材料泵体结构。The mold structure is photoetched and etched on the silicon wafer, and the plastic or polymer material pump body structure is made by three-dimensional molding processing molding or vacuum hot pressing.
本发明的技术效果:本发明根据经典二维紊动射流理论,应用了具有一定压力的气流可以在微型喷嘴处产生高速射流这一特性,利用MEMS工艺设计了一种微型射流泵。根据经典流体力学理论,完成了气-气、气-液、液-气、液-液微型射流泵的设计制作和测试。这种微型射流泵适用于各种流体的微量输运,具有结构简单、泵体材料的可选择范围大、工艺实现容易、驱动方式简单无需外加复杂的电、磁、热等驱动系统等特点,使其易于和大多数微流体系统集成,延长了微泵的使用寿命,提高了其工作的稳定性。Technical effects of the present invention: According to the classic two-dimensional turbulent jet theory, the present invention uses the characteristic that the airflow with a certain pressure can generate high-speed jet at the micro nozzle, and designs a micro jet pump by using MEMS technology. According to the classical fluid mechanics theory, the design, fabrication and testing of gas-gas, gas-liquid, liquid-gas, liquid-liquid micro jet pumps have been completed. This micro-jet pump is suitable for micro-transportation of various fluids. It has the characteristics of simple structure, wide range of choices for pump body materials, easy process realization, simple driving mode and no need for additional complicated electric, magnetic, thermal and other driving systems. It makes it easy to integrate with most microfluidic systems, prolongs the service life of the micropump, and improves its working stability.
众所周知一般意义的生物芯片都是即抛型的,微型射流泵的最大优势在于除了可以采用MEMS工艺在硅片上加工以外,还包括基于塑料或聚合物材料的三维成型加工方法如模塑法和热压法,使其易与一些廉价的塑料或聚合物材料芯片集成,这就大大降低了整个芯片的制作成本。从而为其在生物、医学检测领域的广泛应用打下了坚实的基础,我们可以将它集成在PCR阵列式芯片或化学分析芯片上顺利实现反应物的进样。It is well known that biochips in the general sense are disposable. The biggest advantage of micro jet pumps is that in addition to processing on silicon wafers using MEMS technology, it also includes three-dimensional molding processing methods based on plastic or polymer materials such as molding and The hot pressing method makes it easy to integrate with some cheap plastic or polymer material chips, which greatly reduces the production cost of the entire chip. Therefore, it has laid a solid foundation for its wide application in the field of biological and medical detection. We can integrate it on a PCR array chip or a chemical analysis chip to smoothly realize the injection of reactants.
本发明所述及的微型射流泵驱动压力较低,40kPa的压力即可使其开始工作,一般的医用注射器就可以驱动其工作。The driving pressure of the miniature jet pump mentioned in the present invention is relatively low, and the pressure of 40kPa can make it start to work, and a general medical syringe can drive it to work.
附图说明Description of drawings
下面结合附图,对本项发明做出详细描述。Below in conjunction with accompanying drawing, this invention is described in detail.
图1为本发明微型射流泵平面结构示意图;Fig. 1 is the schematic diagram of the planar structure of the micro jet pump of the present invention;
图2微型射流泵测试结构原理示意图;Fig. 2 schematic diagram of micro jet pump test structure principle;
图3为驱动压力与射流泵背压关系的拟合曲线;Fig. 3 is the fitting curve of the relationship between driving pressure and jet pump back pressure;
图4多级喷嘴并用的微型射流泵平面结构示意图;Figure 4 is a schematic diagram of the planar structure of a micro-jet pump with multi-stage nozzles;
图5微型射流泵工艺制作流程剖面图;Figure 5 is a cross-sectional view of the micro jet pump process;
图6硅片上腐蚀出的泵体结构电镜照片。Fig. 6 Electron micrograph of pump body structure corroded on silicon wafer.
具体实施方式:Detailed ways:
图1为本发明提供的微型射流泵的平面结构示意图。该微型射流泵的主体包括驱动结构和抽吸结构,驱动结构是由射流喷嘴4和与之相连的驱动腔2组成,其中驱动腔2上设有驱动流体入口孔1,驱动流体入口孔1位于驱动腔2上部所对应的某一位置,是与外部管路连接的接口,驱动腔2可以是方形、圆形或椭圆形等。驱动腔2和射流喷嘴4一起构成了产生射流的驱动结构。本发明也可将驱动腔2密封,通过微加工的方法加工出泵腔膜,在其上粘压电片,磁片,形状记忆合金膜或在泵腔的上下表面各加一层膜电极,亦可通过压电,电磁和静电或指压等方式驱动而产生射流,驱动其工作。当射流射入静止的环境中时,与周围静止流体之间的间断面处产生涡旋,涡旋卷吸周围流体进入射流,随同原来射出的流体向前连续流动,从而形成负压,可以通过改变射流喷嘴的截面形状和出口处环形截面的尺寸,控制微型射流泵的工作性能。抽吸结构包括抽吸端口、抽吸流道3和扩散出口5,抽吸流道3设在射流喷嘴的两侧。本发明微型射流泵的工作过程如下:在驱动流体入口孔1打入高压气流,经驱动腔2,在射流喷嘴4的出口处产生高速射流,射流流体与周围静止流体之间存在速度不连续的间断面,间断面一般不可避免受到干扰,失去稳定,从而在抽吸流道5的出口处产生涡旋,涡旋卷吸两侧抽吸流道3内的气体进入射流,同时不断移动、变形、分裂产生紊动,其影响逐渐向内外两侧发展形成内外两个自由紊动的混合层,由于动量的横向传递,卷吸进入的流体取得动量而随同原来射出的流体向前流动进入扩散出口5,形成不同流道内流体的混合段,在混合层中形成一定的流速梯度,出现剪切层,原来的流体失去动量而降低速度,扩散出口5的主要作用是将射流喷嘴4出口处的动能转变为压能,如此连续的工作,以达到抽真空的目的。调节微型射流泵各个结构的尺寸,可以实现不同流量范围的控制。另外泵加工成形以后,可以通过调节驱动气体的压强值,继而控制微型射流泵的流量。Fig. 1 is a schematic plan view of the micro jet pump provided by the present invention. The main body of the micro-jet pump includes a driving structure and a suction structure. The driving structure is composed of a
为了便于测量我们在微型射流泵泵体的左侧设计了入口腔6和入口7,如图2所示,入口7位于入口腔上部的某一位置。在实际应用中,入口腔6可以设计成各种样式的微流体芯片,微型射流泵的抽吸端口与入口腔6相连,抽吸芯片内的气体或液体,从而在芯片内部产生负压,牵引液体充满芯片,负压牵引液体流动的方式可以避免在微流体芯片的内部产生气泡。In order to facilitate the measurement, we designed the
我们分别在驱动管道内(即驱动气体的入口处到射流的出口处)和喷嘴出口处的环形截面上用伯努利方程:We use the Bernoulli equation on the annular section in the driving pipeline (ie, from the inlet of the driving gas to the outlet of the jet) and at the outlet of the nozzle respectively:
这里Ppump是驱动气体的压力,V0是喷嘴出口处气体的速度,Ploss是管道内压力的损失,P0是气体静压力即大气压,Ps是喷嘴出口处所产生的负压.由此式我们可以求出喷嘴出口处的流速V0。Here P pump is the pressure of the driving gas, V 0 is the velocity of the gas at the nozzle outlet, P loss is the pressure loss in the pipeline, P 0 is the static pressure of the gas, that is, atmospheric pressure, and P s is the negative pressure generated at the nozzle outlet. We can find the flow velocity V 0 at the outlet of the nozzle.
根据二维不可压缩等密度紊动射流理论.射流轴线上的速度Vm和卷吸速度Vc可以表示为:According to the theory of two-dimensional incompressible equal-density turbulent jet, the velocity V m and entrainment velocity V c on the jet axis can be expressed as:
这里b0是喷嘴的宽度,x为射流面和出射原点距离,ε的值是根据实验得出的经验值0.154。Here b 0 is the width of the nozzle, x is the distance between the jet surface and the exit origin, and the value of ε is the empirical value 0.154 obtained from experiments.
射流泵驱动的任何流体的平均流速 可以通过下式估算而得Average flow rate of any fluid driven by a jet pump can be estimated by the following formula
这里d是管道的水利直径,ΔP是产生的压差,μ是液体的粘度系数,l是管长。Here d is the hydraulic diameter of the pipe, ΔP is the pressure difference generated, μ is the viscosity coefficient of the liquid, and l is the pipe length.
微型射流泵的背压测量:在器件的驱动进气口1处打入高压驱动气体,入口7处连一毛细玻璃管,将玻璃毛细管的末端垂直置入水中,在不同的气体驱动压力下,上升液面的稳定高度不同,因此我们可以得出不同驱动压力与背压的关系曲线。参考图3,可以看出:结果基本与理论符合成线性关系,而且微型射流泵的工作压力较低。The back pressure measurement of the micro jet pump: inject high-pressure driving gas into the
为了提高射流泵的效率,可以采用多级喷嘴结构并用的泵体形式。参见图4,抽吸流道为若干个流道,每个流道相互平行,流道的末端形成喷嘴;流体流经流道的末端时,会在出口处产生高速射流,同时在其边界处产生涡旋,涡旋卷吸相邻流道内的流体进入射流。In order to improve the efficiency of the jet pump, a pump body with a multi-stage nozzle structure can be used. Referring to Figure 4, the suction flow channel is a number of flow channels, each flow channel is parallel to each other, and the end of the flow channel forms a nozzle; when the fluid flows through the end of the flow channel, a high-speed jet will be generated at the exit, and at the same time at its boundary A vortex is created which entrains fluid in an adjacent flow channel into the jet.
除了气-气微型射流泵,我们也可以依据同样的原理得到气-液,液-液和液-气射流泵,但是由于微小尺度下液体的表面张力作用显著,阻力增加,相应的驱动压力也会增加。In addition to air-air micro-jet pumps, we can also obtain air-liquid, liquid-liquid and liquid-air jet pumps based on the same principle, but due to the significant effect of the surface tension of the liquid on a micro scale, the resistance increases, and the corresponding driving pressure also increases. will increase.
微型射流泵使用形式还可以为:两侧进气产生射流抽吸中间管道内的流体,即将驱动结构和抽吸结构功能互换,具体为进气口7注入高压驱动气体,在两侧的抽吸流道3的出口产生射流,射流边界产生涡旋,卷吸射流喷嘴4和驱动腔内的气体。The use form of the micro jet pump can also be: the air intake on both sides generates jets to suck the fluid in the middle pipeline, that is, the functions of the driving structure and the suction structure are interchanged, specifically, the high-pressure driving gas is injected into the
参考图5,微型射流泵可以通过以下工艺方案实现:Referring to Figure 5, the micro jet pump can be realized through the following process scheme:
方案一、MEMS加工工艺
1、硅片加工工艺,具体的工艺流程如下:1. Silicon wafer processing technology, the specific process is as follows:
1)如图5-a所示硅片9上光刻显影露出要刻蚀的部分(即微型扩散泵的泵体结构);1) As shown in Figure 5-a, the photolithographic development on the silicon wafer 9 exposes the part to be etched (ie the pump body structure of the micro diffusion pump);
2)如图5-b所示,硅片9上腐蚀出泵体结构,具体的腐蚀深度根据性能指标确定(干法刻蚀和湿法刻蚀均可)。2) As shown in Figure 5-b, the pump body structure is etched on the silicon wafer 9, and the specific etching depth is determined according to the performance index (dry etching and wet etching are both acceptable).
2、盖片的加工工艺,具体的工艺流程如下:2. The processing technology of the cover sheet, the specific process is as follows:
如图5-c所示,在玻璃或塑料、聚合物、硅片等材料的盖片11上光刻刻蚀出打孔标记12;如图5-d所示,盖片11上打通孔13(与外部管路的连接口);As shown in Figure 5-c, the
3、硅片和盖片对准键合。3. Alignment and bonding of silicon wafer and cover sheet.
如图5-e所示,刻蚀完的硅片10与打好孔的盖片14对准键合(包括阳极键合和聚合物键合等方法)。As shown in FIG. 5-e, the etched
本项专利所设计的微射流泵通过两张光刻版就可以实现微泵结构,一张版是为硅上刻蚀泵体结构所设计的,另外一张是专为玻璃打孔设计的,在某些情况下玻璃打孔的光刻版可以不做,这又进一步降低了制作的成本。The micro-jet pump designed in this patent can realize the micro-pump structure through two photolithography plates. One plate is designed for etching the pump body structure on silicon, and the other is designed for glass drilling. In some cases, the glass perforated photolithography plate can be omitted, which further reduces the production cost.
图6为刻蚀完毕的硅片上的泵体结构的电镜照片,主要结构包括:驱动腔2、抽吸流道3、射流喷嘴4、扩散出口5。FIG. 6 is an electron micrograph of the structure of the pump body on the etched silicon wafer. The main structure includes: a
方案二、三维模塑成型加工方法
1、首先是要制作负模具,其工艺过程为在硅片表面光刻与腐蚀出微型扩散泵泵体的互补结构,具体步骤与方案一硅片的刻蚀步骤相同。模具也可以采用其它材料制得,如SU8等。1. The first step is to make a negative mold. The process is to photoetch and corrode the complementary structure of the micro-diffusion pump body on the surface of the silicon wafer. The specific steps are the same as the etching steps of the silicon wafer in
2、采用基于一些塑料和聚合物材料的三维成型方法如模塑法或热压法等加工方法,利用负模具制得一些塑料或聚合物材料(如PDMS、PFPE和PMMA等)的泵体,微模塑法具体如下:首先要在作为负模具的硅片上长一层聚合物便于拖模,继而将流态的聚合物涂在硅模具上、抽真空、聚合物高温固化、脱模得到与负模具图案互补的泵体结构。最后与打孔的盖片(包括塑料、聚合物和硅片等材料)对准键合,实现微泵的结构。2. The pump body of some plastic or polymer materials (such as PDMS, PFPE and PMMA, etc.) is made by using negative molds based on three-dimensional molding methods such as molding or hot pressing methods based on some plastic and polymer materials. The micro-molding method is as follows: First, a layer of polymer is grown on the silicon wafer as the negative mold to facilitate moulding, and then the fluid polymer is coated on the silicon mold, vacuumed, the polymer is cured at high temperature, and demoulding is obtained. Pump body structure complementary to negative mold pattern. Finally, it is aligned and bonded with a perforated cover sheet (including materials such as plastics, polymers, and silicon wafers) to realize the micropump structure.
3、采用塑料、聚合物、玻璃片或硅片作为盖片,如盖片上有入口孔,在盖片上光刻、刻蚀穿通孔图形,在相应的标记位置处打通孔。3. Use plastic, polymer, glass sheet or silicon wafer as the cover sheet. If there is an entrance hole on the cover sheet, photoetch and etch the through-hole pattern on the cover sheet, and drill the through-hole at the corresponding marked position.
4、将以负模具制得的塑料或聚合物泵体与盖片对准键合。4. Align and bond the plastic or polymer pump body made by the negative mold with the cover sheet.
这种基于塑料和聚合物材料的三维成型加工方法使得此种微型射流泵易与一些廉价材料芯片集成,这就大大降低了整个芯片的制作成本,从而为其在生物、医学检测领域的广泛应用打下了坚实的基础。This three-dimensional molding processing method based on plastic and polymer materials makes the micro jet pump easy to integrate with some cheap material chips, which greatly reduces the production cost of the entire chip, thus making it widely used in the fields of biological and medical detection. Laid a solid foundation.
Claims (9)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100434728C (en) * | 2005-04-07 | 2008-11-19 | 北京大学 | Micro diffusion pump and its preparation method |
| US8109083B2 (en) * | 2007-11-05 | 2012-02-07 | Cummins Filtration Ip, Inc. | Aspirator support structure |
| US9523358B2 (en) * | 2009-02-12 | 2016-12-20 | The Board Of Trustees Of The University Of Illinois | Magnetically driven micropump |
| JP6003020B2 (en) * | 2011-08-03 | 2016-10-05 | ソニー株式会社 | Microchip and fine particle analyzer |
| CN103864000B (en) * | 2014-02-28 | 2016-02-03 | 西南交通大学 | A kind of electric conjugation fluidic micropumps |
| DE102015224624B3 (en) * | 2015-12-08 | 2017-04-06 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Free-jet metering system for delivering a fluid into or under the skin |
| WO2018191008A1 (en) * | 2017-04-10 | 2018-10-18 | 3M Innovative Properties Company | Powder jet pump |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5224843A (en) * | 1989-06-14 | 1993-07-06 | Westonbridge International Ltd. | Two valve micropump with improved outlet |
| JP2002356224A (en) * | 2001-03-30 | 2002-12-10 | Trinity Ind Corp | Ejector, minute solid piece recovering device and fluid conveyor |
| US20030223880A1 (en) * | 2002-05-29 | 2003-12-04 | Yung-Chiang Chung | A pneumatic driving device for micro fluids wherein fluid pumping is governed by the control of the flow and direction of incident plural gas streams |
| US20040172966A1 (en) * | 2003-03-05 | 2004-09-09 | Yukikatsu Ozaki | Ejector with tapered nozzle and tapered needle |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5224843A (en) * | 1989-06-14 | 1993-07-06 | Westonbridge International Ltd. | Two valve micropump with improved outlet |
| JP2002356224A (en) * | 2001-03-30 | 2002-12-10 | Trinity Ind Corp | Ejector, minute solid piece recovering device and fluid conveyor |
| US20030223880A1 (en) * | 2002-05-29 | 2003-12-04 | Yung-Chiang Chung | A pneumatic driving device for micro fluids wherein fluid pumping is governed by the control of the flow and direction of incident plural gas streams |
| US20040172966A1 (en) * | 2003-03-05 | 2004-09-09 | Yukikatsu Ozaki | Ejector with tapered nozzle and tapered needle |
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