CL2015002743A1 - Proteínas de unión especificas duales dirigidas contra tnfa - Google Patents
Proteínas de unión especificas duales dirigidas contra tnfaInfo
- Publication number
- CL2015002743A1 CL2015002743A1 CL2015002743A CL2015002743A CL2015002743A1 CL 2015002743 A1 CL2015002743 A1 CL 2015002743A1 CL 2015002743 A CL2015002743 A CL 2015002743A CL 2015002743 A CL2015002743 A CL 2015002743A CL 2015002743 A1 CL2015002743 A1 CL 2015002743A1
- Authority
- CL
- Chile
- Prior art keywords
- specific binding
- directed against
- binding proteins
- dual specific
- proteins directed
- Prior art date
Links
- 230000009977 dual effect Effects 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 101150033527 TNF gene Proteins 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
- 230000009870 specific binding Effects 0.000 title 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
Classifications
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- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G01N33/6869—Interleukin
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
PROTEÍNAS DE UNIÓN ESPECIFICAS DUALES DIRIGIDAS CONTRA EL FACTOR DE NECROSIS TUMORAL ALFA (TNF-ALFA); COMPOSICIÓN FARMACÉUTICA QUE LAS COMPRENDE; Y USO.
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US201361794964P | 2013-03-15 | 2013-03-15 |
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CL2015002743A CL2015002743A1 (es) | 2013-03-15 | 2015-09-15 | Proteínas de unión especificas duales dirigidas contra tnfa |
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UY (1) | UY35479A (es) |
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TW202037609A (zh) | 2012-11-01 | 2020-10-16 | 美商艾伯維有限公司 | 抗-vegf/dll4雙重可變區域免疫球蛋白及其用途 |
EP2970459A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against il-1beta and il-17 |
KR102489452B1 (ko) | 2014-02-02 | 2023-01-16 | 메디뮨 리미티드 | Ngf 길항제 도메인 및 tnfa 길항제 도메인으로 구성된 키메라 단백질 |
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PL3104854T3 (pl) | 2014-02-10 | 2020-11-30 | Respivant Sciences Gmbh | Stabilizatory komórek tucznych do leczenia choroby płuc |
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US10238625B2 (en) | 2015-08-07 | 2019-03-26 | Respivant Sciences Gmbh | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
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GB201522394D0 (en) | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
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JP7195929B2 (ja) | 2016-04-13 | 2022-12-26 | サノフイ | 三重特異性および/または三価結合タンパク質 |
BR112018072263A2 (pt) | 2016-04-27 | 2019-02-12 | Abbvie Inc. | métodos de tratamento de doenças nas quais atividade de il-13 é prejudicial usando anti-anticorpos anti-il-13 |
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ZA201506582B (en) | 2017-01-25 |
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CR20150522A (es) | 2016-01-12 |
ECSP15040888A (es) | 2015-11-30 |
WO2014144299A2 (en) | 2014-09-18 |
CN105209491A (zh) | 2015-12-30 |
AU2014227664A1 (en) | 2015-09-24 |
EP2970457A2 (en) | 2016-01-20 |
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