CH649553A5 - Azepinoindole und verfahren zu deren herstellung. - Google Patents

Azepinoindole und verfahren zu deren herstellung. Download PDF

Info

Publication number: CH649553A5
Authority: CH; Switzerland
Prior art keywords: compounds; formula; alkyl; mixture; solution
Prior art date: 1982-05-06

Application number

CH2806/82A

Other languages

German (de)

English (en)

Inventor

Fulvio Dr Gadient

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-06

Filing date

1982-05-06

Publication date

1985-05-31

1982-05-06 Application filed by Sandoz Ag filed Critical Sandoz Ag

1982-05-06 Priority to CH2806/82A priority Critical patent/CH649553A5/de

1983-04-27 Priority to FR8307089A priority patent/FR2526434A1/fr

1983-04-28 Priority to BE1/10774A priority patent/BE896590A/fr

1983-04-28 Priority to DE19833315467 priority patent/DE3315467A1/de

1983-04-29 Priority to FI831475A priority patent/FI831475L/fi

1983-05-02 Priority to ES522008A priority patent/ES522008A0/es

1983-05-03 Priority to NL8301552A priority patent/NL8301552A/nl

1983-05-04 Priority to SE8302554A priority patent/SE8302554L/xx

1983-05-04 Priority to GB08312159A priority patent/GB2120662B/en

1983-05-04 Priority to PT76632A priority patent/PT76632B/pt

1983-05-04 Priority to IL68576A priority patent/IL68576A0/xx

1983-05-04 Priority to DK199883A priority patent/DK199883A/da

1983-05-04 Priority to HU831531A priority patent/HU189275B/hu

1983-05-04 Priority to JP58078869A priority patent/JPS58203993A/ja

1983-05-05 Priority to AU14256/83A priority patent/AU1425683A/en

1983-05-06 Priority to IT48232/83A priority patent/IT1197644B/it

1983-05-06 Priority to ZA833266A priority patent/ZA833266B/xx

1985-05-31 Publication of CH649553A5 publication Critical patent/CH649553A5/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CH2806/82A 1982-05-06 1982-05-06 Azepinoindole und verfahren zu deren herstellung. CH649553A5 (de)

Priority Applications (17)

Application Number	Priority Date	Filing Date	Title
CH2806/82A CH649553A5 (de)	1982-05-06	1982-05-06	Azepinoindole und verfahren zu deren herstellung.
FR8307089A FR2526434A1 (fr)	1982-05-06	1983-04-27	Nouveaux azepino-indoles, leur preparation et leur utilisation comme medicaments
BE1/10774A BE896590A (fr)	1982-05-06	1983-04-28	Nouveaux azepino-indoles leur preparation et leur utilisation comme medicaments
DE19833315467 DE3315467A1 (de)	1982-05-06	1983-04-28	Azepinoindole, verfahren zu deren herstellung und diese enthaltende arzneimittel
FI831475A FI831475L (fi)	1982-05-06	1983-04-29	Nya azepinindoler, deras framstaellning och dessa innehaollande farmaceutiska foereningar
ES522008A ES522008A0 (es)	1982-05-06	1983-05-02	Procedimiento para preparar acepinoindoles.
NL8301552A NL8301552A (nl)	1982-05-06	1983-05-03	Nieuwe azepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
SE8302554A SE8302554L (sv)	1982-05-06	1983-05-04	Nya azepinoindoler, deras framstellning samt farmaceutiska kompositioner innehallande desamma
GB08312159A GB2120662B (en)	1982-05-06	1983-05-04	New azepinoindoles their production and pharmaceutical compositions containing them
PT76632A PT76632B (en)	1982-05-06	1983-05-04	Process for the preparation of 1-alkyl-1,2,3,4,5,6-hexahydro-azepine <4,5-b> indoles
IL68576A IL68576A0 (en)	1982-05-06	1983-05-04	Azepinoindoles,their production and pharmaceutical compositions containing them
DK199883A DK199883A (da)	1982-05-06	1983-05-04	Fremgangsmaade til fremstilling af azepinoindoler
HU831531A HU189275B (en)	1982-05-06	1983-05-04	Process for preparing azepino-indole derivatives and pharmaceutical compositions containing such compounds
JP58078869A JPS58203993A (ja)	1982-05-06	1983-05-04	新規アゼピノインド−ル、その製造法およびそれからなる医薬
AU14256/83A AU1425683A (en)	1982-05-06	1983-05-05	1-alkyl-1,2,3,4,5,6-hexahydroazepino(4,5-6)indoles
IT48232/83A IT1197644B (it)	1982-05-06	1983-05-06	Azepinoindoli,loro preparazione e loro impiego come medicamenti
ZA833266A ZA833266B (en)	1982-05-06	1983-05-06	New azepino indoles,their production and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH2806/82A CH649553A5 (de)	1982-05-06	1982-05-06	Azepinoindole und verfahren zu deren herstellung.

Publications (1)

Publication Number	Publication Date
CH649553A5 true CH649553A5 (de)	1985-05-31

Family

ID=4242007

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH2806/82A CH649553A5 (de)	1982-05-06	1982-05-06	Azepinoindole und verfahren zu deren herstellung.

Country Status (17)

Country	Link
JP (1)	JPS58203993A (af)
AU (1)	AU1425683A (af)
BE (1)	BE896590A (af)
CH (1)	CH649553A5 (af)
DE (1)	DE3315467A1 (af)
DK (1)	DK199883A (af)
ES (1)	ES522008A0 (af)
FI (1)	FI831475L (af)
FR (1)	FR2526434A1 (af)
GB (1)	GB2120662B (af)
HU (1)	HU189275B (af)
IL (1)	IL68576A0 (af)
IT (1)	IT1197644B (af)
NL (1)	NL8301552A (af)
PT (1)	PT76632B (af)
SE (1)	SE8302554L (af)
ZA (1)	ZA833266B (af)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU193083B (en) *	1984-02-22	1987-08-28	Sandoz Ag	Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds
AU582564B2 (en) *	1985-02-20	1989-04-06	Sandoz Ltd.	2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
EP1319004A2 (en) *	2000-09-20	2003-06-18	PHARMACIA & UPJOHN COMPANY	Substituted azepino[4,5-b]indole derivatives
ATE306486T1 (de) *	2001-08-08	2005-10-15	Pharmacia & Upjohn Co Llc	Therapeutische 1h-pyrido(4,3-b)indole
US7893051B2 (en) *	2006-01-19	2011-02-22	Athersys, Inc.	Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof
NZ586120A (en)	2008-01-11	2012-07-27	Albany Molecular Res Inc	(1-azinone) -substituted pyridoindoles as mch antagonists
WO2011003012A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
EP2448585B1 (en)	2009-07-01	2014-01-01	Albany Molecular Research, Inc.	Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en)	2010-12-21	2014-04-15	Albany Molecular Research, Inc.	Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3070467D1 (en) *	1979-11-02	1985-05-15	Sandoz Ag	Azepinoindoles, process for their production and pharmaceutical compositions containing them

1982
- 1982-05-06 CH CH2806/82A patent/CH649553A5/de not_active IP Right Cessation
1983
- 1983-04-27 FR FR8307089A patent/FR2526434A1/fr active Pending
- 1983-04-28 BE BE1/10774A patent/BE896590A/fr not_active IP Right Cessation
- 1983-04-28 DE DE19833315467 patent/DE3315467A1/de not_active Withdrawn
- 1983-04-29 FI FI831475A patent/FI831475L/fi not_active Application Discontinuation
- 1983-05-02 ES ES522008A patent/ES522008A0/es active Granted
- 1983-05-03 NL NL8301552A patent/NL8301552A/nl not_active Application Discontinuation
- 1983-05-04 GB GB08312159A patent/GB2120662B/en not_active Expired
- 1983-05-04 SE SE8302554A patent/SE8302554L/xx not_active Application Discontinuation
- 1983-05-04 DK DK199883A patent/DK199883A/da not_active Application Discontinuation
- 1983-05-04 IL IL68576A patent/IL68576A0/xx unknown
- 1983-05-04 HU HU831531A patent/HU189275B/hu unknown
- 1983-05-04 PT PT76632A patent/PT76632B/pt unknown
- 1983-05-04 JP JP58078869A patent/JPS58203993A/ja active Pending
- 1983-05-05 AU AU14256/83A patent/AU1425683A/en not_active Abandoned
- 1983-05-06 ZA ZA833266A patent/ZA833266B/xx unknown
- 1983-05-06 IT IT48232/83A patent/IT1197644B/it active

Also Published As

Publication number	Publication date
ES8502440A1 (es)	1985-01-01
FI831475L (fi)	1983-11-07
ZA833266B (en)	1984-12-24
NL8301552A (nl)	1983-12-01
GB2120662A (en)	1983-12-07
DE3315467A1 (de)	1983-11-17
ES522008A0 (es)	1985-01-01
GB8312159D0 (en)	1983-06-08
HU189275B (en)	1986-06-30
FI831475A0 (fi)	1983-04-29
SE8302554L (sv)	1983-11-07
FR2526434A1 (fr)	1983-11-10
IT8348232A0 (it)	1983-05-06
IT1197644B (it)	1988-12-06
JPS58203993A (ja)	1983-11-28
IL68576A0 (en)	1983-09-30
SE8302554D0 (sv)	1983-05-04
GB2120662B (en)	1985-09-11
BE896590A (fr)	1983-10-28
AU1425683A (en)	1983-11-10
DK199883A (da)	1983-11-07
PT76632A (en)	1983-06-01
PT76632B (en)	1986-01-27
DK199883D0 (da)	1983-05-04

Publication	Publication Date	Title
CH648553A5 (de)	1985-03-29	Neue 3,4-dihydro-5h-2,3-benzodiazepin-derivate und verfahren zur herstellung derselben.
CH649553A5 (de)	1985-05-31	Azepinoindole und verfahren zu deren herstellung.
DD149071A5 (de)	1981-06-24	Herstellung 2-substituierter trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido eckige klammer auf 4,3-b eckige klammer zu indole
CH646696A5 (de)	1984-12-14	Dibenzazepine, ihre herstellung und verwendung.
DE3500251C2 (de)	1995-01-26	Neue 8alpha-Acylaminoergoline
CH643263A5 (de)	1984-05-30	Benzodiazepine, ihre herstellung und verwendung.
DE2708111A1 (de)	1977-09-01	Aminoalkylpyrrolbenzoxaazaalkane
DE2628570B2 (af)	1980-02-07
DE2429290A1 (de)	1975-01-16	Tricyclische kondensierte imidazolderivate und verfahren zu ihrer herstellung
CH617701A5 (af)	1980-06-13
DE2051962A1 (de)	1971-04-29	Benzimidazo eckige Klammer auf l,2d eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu benzodiazepin 6 (5H) one und Verfahren zu deren Her stellung
DE1901497A1 (de)	1969-08-28	Neue heterocyclische Verbindungen und Verfahren zu ihrer Herstellung
DE2609437C2 (af)	1987-10-01
EP0233483A2 (de)	1987-08-26	Pyrrolo[1,2-a][4,1]benzoxazepine, Verfahren zur ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie therapeutische Verwendung
DE2609862A1 (de)	1976-10-07	Verbindungen mit antidepressiver wirkung
CH644126A5 (de)	1984-07-13	4-phenyl-thieno-(2,3-c)-piperidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen.
DE2542791A1 (de)	1976-04-15	N,n'-disubstituierte naphthylacetamidine
EP0120439B1 (de)	1987-01-14	7,8,9,10-Tetrahydrothieno-(3,2-e)-pyrido-(4,3-b)-indole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE1620373A1 (de)	1970-04-02	Verfahren zur Herstellung von neuen heterocyclischen Verbindungen
CH461489A (de)	1968-08-31	Verfahren zur Herstellung von neuen Oxazolderivaten
DE2610679C2 (de)	1985-09-12	Sulfinylgruppenhaltige Oximätherderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Mittel
DE3505017A1 (de)	1985-08-22	Diazepinoindole, verfahren zu deren herstellung und diese enthaltende arzneimittel
DD215540A5 (de)	1984-11-14	Verfahren zur herstellung von benzazepinderivaten
CH626083A5 (af)	1981-10-30
DE1770775A1 (de)	1971-12-09	Neue Dibenzazepinderivate und Verfahren zu ihrer Herstellung

Legal Events

Date	Code	Title	Description
1987-01-30	PL	Patent ceased
2024-10-31	PL	Patent ceased