CH630897A5 - Process for preparing novel prostaglandin analogues having a triple bond between C-13 and C-14. - Google Patents

Info

Publication number

CH630897A5

CH630897A5 CH102677A CH102677A CH630897A5 CH 630897 A5 CH630897 A5 CH 630897A5 CH 102677 A CH102677 A CH 102677A CH 102677 A CH102677 A CH 102677A CH 630897 A5 CH630897 A5 CH 630897A5

Authority

CH

Switzerland

Prior art keywords

compounds

hydrogen

methyl

carbon atoms

compound

Prior art date

1976-02-17

Links

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• 238000004519 manufacturing process Methods 0.000 title description 4
• 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title description 3
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• 238000000034 method Methods 0.000 claims description 91
• 150000003180 prostaglandins Chemical class 0.000 claims description 88
• 239000000203 mixture Substances 0.000 claims description 47
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 42
• 125000004432 carbon atom Chemical group C* 0.000 claims description 41
• 239000002253 acid Substances 0.000 claims description 38
• 239000001257 hydrogen Substances 0.000 claims description 35
• 229910052739 hydrogen Inorganic materials 0.000 claims description 35
• 238000002360 preparation method Methods 0.000 claims description 34
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• 229910052731 fluorine Inorganic materials 0.000 claims description 13
• 239000011737 fluorine Substances 0.000 claims description 13
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• 150000001768 cations Chemical class 0.000 claims description 10
• PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 9
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• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
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