CH474541A - Verfahren zum Überführen saurer kristalliner Triterpen-Saponine in Triterpen-Saponine erhöhter Wasserlöslichkeit - Google Patents
Verfahren zum Überführen saurer kristalliner Triterpen-Saponine in Triterpen-Saponine erhöhter WasserlöslichkeitInfo
- Publication number
- CH474541A CH474541A CH1488663A CH1488663A CH474541A CH 474541 A CH474541 A CH 474541A CH 1488663 A CH1488663 A CH 1488663A CH 1488663 A CH1488663 A CH 1488663A CH 474541 A CH474541 A CH 474541A
- Authority
- CH
- Switzerland
- Prior art keywords
- triterpene saponins
- water solubility
- increased water
- acidic crystalline
- triterpene
- Prior art date
Links
- 229930182493 triterpene saponin Natural products 0.000 title 2
- 230000002378 acidificating effect Effects 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM55118A DE1282852B (de) | 1962-12-14 | 1962-12-14 | Peroral anwendbares aescinhaltiges Arzneimittel |
| CH1488763 | 1963-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH474541A true CH474541A (de) | 1969-06-30 |
Family
ID=25715271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1488663A CH474541A (de) | 1962-12-14 | 1963-12-04 | Verfahren zum Überführen saurer kristalliner Triterpen-Saponine in Triterpen-Saponine erhöhter Wasserlöslichkeit |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3238104A (de) |
| AT (1) | AT245733B (de) |
| BE (1) | BE641151A (de) |
| CH (1) | CH474541A (de) |
| DE (2) | DE1282852B (de) |
| DK (1) | DK107183C (de) |
| FR (1) | FR3473M (de) |
| GB (1) | GB1017960A (de) |
| IT (1) | IT1150100B (de) |
| NL (2) | NL142595B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51139613A (en) * | 1975-05-24 | 1976-12-02 | Nippon Shinyaku Co Ltd | An absorbable non-crystalline sterol glycoside monopalmitate ester and a method for preparing its pharmaceutical |
| DE2530953C3 (de) * | 1975-07-11 | 1994-07-07 | Madaus Ag | Verfahren zur Herstellung von röntgenamorphem Aescin, nach diesem Verfahren erhältliches röntgenamorphes Aescin und dieses enthaltende Arzneimittel |
| JPS5948810B2 (ja) * | 1980-03-22 | 1984-11-29 | 山之内製薬株式会社 | ニカルジピン持続性製剤用組成物 |
| CN116115566B (zh) * | 2021-11-15 | 2025-02-14 | 上海维洱生物医药科技有限公司 | 一种七叶皂苷钠脂质体及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2123248A (en) * | 1937-01-14 | 1938-07-12 | Louis N Markwood | Insoluble reaction products of peat and process of making same |
| US2350804A (en) * | 1939-07-22 | 1944-06-06 | Ohta Masaki | Derivatives of hesperidin and process for preparing the same |
| US2691654A (en) * | 1952-06-11 | 1954-10-12 | Buroughs Wellcome & Co U S A I | Amino heterocycles and method of making |
| DE1134180B (de) * | 1954-01-22 | 1962-08-02 | Nitritfabrik Ges Mit Beschraen | Verfahren zur Umwandlung von therapeutisch anwendbaren, in Wasser praktisch unloeslichen organischen Stoffen in ein echt wasserloesliches Produkt |
| US2780620A (en) * | 1954-01-28 | 1957-02-05 | Merle M Krider | Partial acidic hydrolysis of steroidal saponins |
| US3110711A (en) * | 1960-06-14 | 1963-11-12 | Klinge Co Chem Pharm Fab | Process of producing two escin isomers from horse chestnut extracts, and products |
-
0
- NL NL301747D patent/NL301747A/xx unknown
-
1962
- 1962-12-14 DE DEM55118A patent/DE1282852B/de active Pending
-
1963
- 1963-12-04 CH CH1488663A patent/CH474541A/de not_active IP Right Cessation
- 1963-12-11 DK DK577663AA patent/DK107183C/da active
- 1963-12-12 FR FR957029A patent/FR3473M/fr active Active
- 1963-12-12 BE BE641151A patent/BE641151A/xx unknown
- 1963-12-12 AT AT997463A patent/AT245733B/de active
- 1963-12-12 NL NL63301747A patent/NL142595B/xx not_active IP Right Cessation
- 1963-12-12 IT IT25495/63A patent/IT1150100B/it active
- 1963-12-13 US US330479A patent/US3238104A/en not_active Expired - Lifetime
- 1963-12-16 GB GB49629/63A patent/GB1017960A/en not_active Expired
-
1964
- 1964-12-05 DE DE19641493999 patent/DE1493999A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE1282852B (de) | 1968-11-14 |
| AT245733B (de) | 1966-03-10 |
| DK107183C (da) | 1967-05-01 |
| BE641151A (de) | 1964-04-01 |
| NL301747A (de) | |
| GB1017960A (en) | 1966-01-26 |
| FR3473M (fr) | 1965-08-09 |
| IT1150100B (it) | 1986-12-10 |
| US3238104A (en) | 1966-03-01 |
| DE1493999A1 (de) | 1970-02-05 |
| NL142595B (nl) | 1974-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |