[go: up one dir, main page]

CH188810A - Process for the preparation of a substituted amide of a fatty aromatic acid. - Google Patents

Process for the preparation of a substituted amide of a fatty aromatic acid.

Info

Publication number
CH188810A
CH188810A CH188810DA CH188810A CH 188810 A CH188810 A CH 188810A CH 188810D A CH188810D A CH 188810DA CH 188810 A CH188810 A CH 188810A
Authority
CH
Switzerland
Prior art keywords
preparation
substituted amide
aromatic acid
fatty aromatic
amide
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH188810A publication Critical patent/CH188810A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Herstellung eines substituierten     Amides    einer     fettaromatischen    Säure.    Es wurde gefunden, dass man zu einem  substituierten     Amid    einer fettaromatischen  Säure gelangen kann, wenn man einen reak  tionsfähigen Ester des     Dimethylaminoäthanols     auf ein Metallderivat des     Diphenylessigsäure-          amides    einwirken lässt.  



  Das so erhaltene     Diphenylessigsäure-2-          dinrethylamirroäthylanrid    ist identisch mit der  in der Patentschrift Nr. 182891     beschriebenen     Verbindung.  



  <I>Beispiel:</I>  21 Teile     Diphenylessigsäureamid    und  4 Teile     Natriumamid    werden in 200 Teilen       Toluol    bis zur Beendigung der Ammoniak  entwicklung erwärmt. Nun fügt man die  berechnete Menge     Chloräthyldimethylamin     hinzu und erhitzt bis zur beendeten Reaktion  weiter. Nach dem Erkalten wird mit ver  dünnter Säure ausgezogen und aus der fil  trierten     wässrigen    Lösung die Base in übli  cher Weise abgeschieden.  



  An Stelle von     Ohloräthyldimethylamin     können auch andere reaktionsfähige Ester des       Dimethylaminoäthanols,    zum Beispiel der    Bromwasserstoff-, der     Jodwasserstoff-,    oder  der     Toluolsulfonsäureester    Verwendung fin  den. Zur Herstellung der Metallverbindung  des     Carbonsäureamides    kann man auch andere       Metallamide,    wie zum Beispiel Kalium- oder       Kalziumamid,        iyletallalkoholate,    wie zum Bei  spiel Natrium- oder     Kaliumalkoholat,    oder  reaktionsfähige Metalle wie zum Beispiel  Natrium, Kalium, usw., gebrauchen.



  Process for the preparation of a substituted amide of a fatty aromatic acid. It has been found that a substituted amide of a fatty acid can be obtained if a reactive ester of dimethylaminoethanol is allowed to act on a metal derivative of diphenylacetic acid amide.



  The diphenylacetic acid-2-dinrethylamirroethyl anride thus obtained is identical to the compound described in patent specification No. 182891.



  <I> Example: </I> 21 parts of diphenylacetic acid amide and 4 parts of sodium amide are heated in 200 parts of toluene until the evolution of ammonia has ended. Now add the calculated amount of chloroethyldimethylamine and continue heating until the reaction has ended. After cooling, the mixture is extracted with dilute acid and the base is deposited in the usual way from the filtered aqueous solution.



  Instead of Ohloräthyldimethylamin other reactive esters of dimethylaminoethanol, for example the hydrogen bromide, the hydrogen iodide, or the toluenesulfonic acid ester can be used. Other metal amides, such as potassium or calcium amide, metal alcoholates such as sodium or potassium alcoholate, or reactive metals such as sodium, potassium, etc., can also be used to produce the metal compound of the carboxamide.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines substituier ten Amides einer fettaromatischen Säure, da durch gekennzeichnet, dass man einen reak tionsfähigen Ester des Dirnethylaminoäthanols auf ein Metallderivat des Diphenylessigsäure- amides einwirken lässt. Das so erhaltene Diphenylessigsäure-2-di- methylarninoäthylamid ist identisch mit der in der Patentschrift Nr. 182891 beschriebe nen Verbindung. PATENT CLAIM: Process for the production of a substituted amide of a fatty aromatic acid, characterized in that a reactive ester of dimethylaminoethanol is allowed to act on a metal derivative of diphenylacetic acid amide. The diphenylacetic acid-2-dimethylaminoethylamide obtained in this way is identical to the compound described in Patent No. 182891.
CH188810D 1933-09-13 1933-09-13 Process for the preparation of a substituted amide of a fatty aromatic acid. CH188810A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH184722T 1933-09-13
CH188810T 1933-09-13

Publications (1)

Publication Number Publication Date
CH188810A true CH188810A (en) 1937-01-15

Family

ID=25721066

Family Applications (1)

Application Number Title Priority Date Filing Date
CH188810D CH188810A (en) 1933-09-13 1933-09-13 Process for the preparation of a substituted amide of a fatty aromatic acid.

Country Status (1)

Country Link
CH (1) CH188810A (en)

Similar Documents

Publication Publication Date Title
CH188810A (en) Process for the preparation of a substituted amide of a fatty aromatic acid.
CH184722A (en) Process for the preparation of a substituted amide of a fatty aromatic acid.
CH188809A (en) Process for the preparation of a substituted amide of a fatty aromatic acid.
CH188811A (en) Process for the preparation of a substituted amide of a fatty aromatic acid.
CH223219A (en) Process for the preparation of a basic amide.
CH156346A (en) Process for the preparation of a basic substituted carboxamide.
CH156349A (en) Process for the preparation of a basic substituted carboxamide.
CH156348A (en) Process for the preparation of a basic substituted carboxamide.
AT153694B (en) Process for the production of ammonium persulphate from solutions by crystallization.
DE375656C (en) Process for the production of iodine compounds or iodine.
CH156344A (en) Process for the preparation of a basic substituted carboxamide.
AT135351B (en) Process for the preparation of aliphatic amino alcohols.
AT164547B (en) Process for the production of vitamin B1
CH156345A (en) Process for the preparation of a basic substituted carboxamide.
DE670768C (en) Process for the production of a bath salt suitable for the preparation of solar baths
DE525185C (en) Process for the preparation of magnesium cyanide
AT152742B (en) Process for the preparation of 10-halo-1,5-phenanthrolines.
DE525654C (en) Process for the preparation of an o-amino-p-cresol carbonic acid
AT116719B (en) Process for making active oxygen releasing soap.
AT160592B (en) Soldering process and flux for carrying out the same.
CH156347A (en) Process for the preparation of a basic substituted carboxamide.
DE707704C (en) Process for the preparation of pyridine compounds
AT125233B (en) Process for the preparation of salt-like compounds from higher homologues of polyoxybenzenes.
CH198137A (en) Process for the preparation of p-sulfamidophenylcarbamic acid choline chloride.
CH156353A (en) Process for the preparation of a basic substituted carboxamide.