CH184723A - Process for the production of basic bismuth sebacate. - Google Patents
Process for the production of basic bismuth sebacate.Info
- Publication number
- CH184723A CH184723A CH184723DA CH184723A CH 184723 A CH184723 A CH 184723A CH 184723D A CH184723D A CH 184723DA CH 184723 A CH184723 A CH 184723A
- Authority
- CH
- Switzerland
- Prior art keywords
- production
- bismuth
- basic bismuth
- sebacic acid
- excess
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Verfahren zur Herstellung von basischen Wismut-Sebaeinat. Gegenstand der vorliegenden Erfindung ist ein Verfahren zur Herstellung eines bis her nicht bekannten basischen Wismut- Sebacinats. Das Verfahren ist dadurch gekenn zeichnet, dass man einen Überschuss von Sebacinsäure bei einer Temperatur von 190 bis 2300 C mit einer Wismutverbindung re agieren lässt, die unter den Reaktionsbedin- Die Reaktion verläuft nach der Gleichung:
gungen den Rest Bi0 an die Sebacinsäure abgibt, und nach vollendeter Reaktion den Überschuss von Säure mit einem Lösungs mittel entfernt.
Als Wismutverbindung kann man Wis- muttrioxyd, Wismuthydroxyd, Wismut-car- bonat oder -subcarbonat verwenden.
Man er hält in jedem Fall das gleiche Endprodukt -COOH - C00. Bi0 (CHs)a -COOH + 2 Bi 0 g = (CHa)s - C00. Bi0 + 2 H g. <I>Beispiel:
</I> 46,6 gr ('/io Mol.) Wismuttrioxyd werden mit 140 gr ('/io Mol.) Sebacinsäure innig ge mischt und in einem Rundkolben mit Hilfe aines Ölbades auf 220" C erhitzt. Die all mählich flüssig werdende Masse wird nun berührt, und zwar so lange, bis alles Wis- nuttrioxyd aufgelöst ist und die Flüssigkeit vollkommen klar erscheint.
Nun wird das ;eschmolze,)P Gemisch in dünnem Strahle auf warmen, kräftig gerührten Alkohol ge gossen und dann abgenutscht.
Der Rückstand des basischen Wismut Sebacinats wird so lange mit Alkohol extra hiert, bis alle freie Säure entfernt ist. Das so erhaltene basische Wismut-Sebacinat ist ein weisses Pulver, unlöslich in Wasser, Al kohol und Äther, löslich in höheren Fett säuren, besonders in der Wärme. Es ist für therapeutische Zwecke bestimmt.
Process for the production of basic bismuth sebaeinate. The present invention relates to a process for the production of a hitherto unknown basic bismuth sebacate. The process is characterized in that an excess of sebacic acid is allowed to react with a bismuth compound at a temperature of 190 to 2300 C, which under the reaction conditions
supplies the rest of Bi0 to the sebacic acid, and after the reaction is complete, the excess acid is removed with a solvent.
Bismuth trioxide, bismuth hydroxide, bismuth carbonate or bismuth subcarbonate can be used as bismuth compounds.
In any case, he keeps the same end product -COOH-C00. Bi0 (CHs) a -COOH + 2 Bi0g = (CHa) s-C00. Bi0 + 2 H g. <I> example:
</I> 46.6 g (1/10 mol.) Of bismuth trioxide are intimately mixed with 140 g (1/10 mol.) Sebacic acid and heated in a round bottom flask to 220 ° C. with the aid of an oil bath. The gradually becoming liquid The mass is now touched until all the knowledge trioxide is dissolved and the liquid appears perfectly clear.
The molten mixture is then poured in a thin stream onto warm, vigorously stirred alcohol and then suction filtered.
The residue of the basic bismuth sebacinate is extracted with alcohol until all free acid has been removed. The basic bismuth sebacate obtained in this way is a white powder, insoluble in water, alcohol and ether, soluble in higher fatty acids, especially when heated. It is intended for therapeutic use.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH184723T | 1935-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH184723A true CH184723A (en) | 1936-06-15 |
Family
ID=4433176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH184723D CH184723A (en) | 1935-08-21 | 1935-08-21 | Process for the production of basic bismuth sebacate. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH184723A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1035192A1 (en) * | 1999-01-26 | 2000-09-13 | Stefan Graichen | Additive for a cooling lubricant |
-
1935
- 1935-08-21 CH CH184723D patent/CH184723A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1035192A1 (en) * | 1999-01-26 | 2000-09-13 | Stefan Graichen | Additive for a cooling lubricant |
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