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CA2336561A1 - Monoclonal antibody to lymphocyte-associated cell surface protein - Google Patents

Monoclonal antibody to lymphocyte-associated cell surface protein Download PDF

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Publication number
CA2336561A1
CA2336561A1 CA002336561A CA2336561A CA2336561A1 CA 2336561 A1 CA2336561 A1 CA 2336561A1 CA 002336561 A CA002336561 A CA 002336561A CA 2336561 A CA2336561 A CA 2336561A CA 2336561 A1 CA2336561 A1 CA 2336561A1
Authority
CA
Canada
Prior art keywords
monoclonal antibody
cell line
lymphocyte
cell surface
surface protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002336561A
Other languages
French (fr)
Other versions
CA2336561C (en
Inventor
Thomas F. Tedder
Olivier G. Spertini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from CA002112408A external-priority patent/CA2112408C/en
Publication of CA2336561A1 publication Critical patent/CA2336561A1/en
Application granted granted Critical
Publication of CA2336561C publication Critical patent/CA2336561C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A hybridoma cell line produced by the fusion of NS-1 myeloma cells with spleen cells obtained from mice immunized with Leukocyte Adhesion Molecule-1 (LAM-1) cDNA transfected cells. The cell line produces a monoclonal antibody reactive with human, monkey, cow, rabbit, sheep, dog, cat, pig and goat LAM-1. The monoclonal antibody produced by the cell line, anti-LAM1-3, may be clinically useful in blocking leukocyte entry into sites of inflammation or tissue injury.
CA002336561A 1991-06-25 1992-06-24 Monoclonal antibody to lymphocyte-associated cell surface protein Expired - Fee Related CA2336561C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72060291A 1991-06-25 1991-06-25
US07/720,602 1991-06-25
CA002112408A CA2112408C (en) 1991-06-25 1992-06-24 Monoclonal antibody to lymphocyte-associated cell surface protein

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002112408A Division CA2112408C (en) 1991-06-25 1992-06-24 Monoclonal antibody to lymphocyte-associated cell surface protein

Publications (2)

Publication Number Publication Date
CA2336561A1 true CA2336561A1 (en) 1993-01-07
CA2336561C CA2336561C (en) 2006-10-31

Family

ID=25676890

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002336561A Expired - Fee Related CA2336561C (en) 1991-06-25 1992-06-24 Monoclonal antibody to lymphocyte-associated cell surface protein

Country Status (1)

Country Link
CA (1) CA2336561C (en)

Also Published As

Publication number Publication date
CA2336561C (en) 2006-10-31

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