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FI952658A0 - With L-selectin reactive humanized antibodies - Google Patents

With L-selectin reactive humanized antibodies

Info

Publication number
FI952658A0
FI952658A0 FI952658A FI952658A FI952658A0 FI 952658 A0 FI952658 A0 FI 952658A0 FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A FI 952658 A0 FI952658 A0 FI 952658A0
Authority
FI
Finland
Prior art keywords
humanized antibodies
selectin
reactive humanized
selectin reactive
reactive
Prior art date
Application number
FI952658A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI952658A7 (en
FI952658L (en
Inventor
Man Sung Co
Original Assignee
Protein Design Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Design Labs Inc filed Critical Protein Design Labs Inc
Publication of FI952658A7 publication Critical patent/FI952658A7/en
Publication of FI952658L publication Critical patent/FI952658L/en
Publication of FI952658A0 publication Critical patent/FI952658A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI952658A 1992-12-01 1993-11-30 With L-selectin reactive humanized antibodies FI952658A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98394692A 1992-12-01 1992-12-01
PCT/US1993/011612 WO1994012215A1 (en) 1992-12-01 1993-11-30 Humanized antibodies reactive with l-selectin

Publications (3)

Publication Number Publication Date
FI952658A7 FI952658A7 (en) 1995-05-31
FI952658L FI952658L (en) 1995-05-31
FI952658A0 true FI952658A0 (en) 1995-05-31

Family

ID=25530200

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952658A FI952658A0 (en) 1992-12-01 1993-11-30 With L-selectin reactive humanized antibodies

Country Status (12)

Country Link
EP (1) EP0671951A4 (en)
JP (1) JPH08503617A (en)
KR (1) KR100371784B1 (en)
AU (1) AU689090B2 (en)
CA (1) CA2149025A1 (en)
CZ (1) CZ140195A3 (en)
FI (1) FI952658A0 (en)
HU (1) HUT71790A (en)
NO (1) NO952160L (en)
PL (1) PL309249A1 (en)
RU (1) RU2151612C1 (en)
WO (1) WO1994012215A1 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
WO1996040942A1 (en) * 1995-06-07 1996-12-19 Cytel Corporation Humanized antibodies to e-selectin
HUP9901673A3 (en) * 1995-08-17 2001-06-28 Scil Biomedicals Gmbh Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage
AU746888B2 (en) * 1995-08-17 2002-05-02 Protein Design Labs, Inc. Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage
AU4594297A (en) * 1996-09-27 1998-04-17 Trustees Of Columbia University In The City Of New York, The Methods for treating an ischemic disorder and improving stroke outcome
US8128963B2 (en) 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
EP0852951A1 (en) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stable lyophilized monoclonal or polyclonal antibodies containing pharmaceuticals
WO1999043353A2 (en) * 1998-02-26 1999-09-02 Boehringer Ingelheim Pharmaceuticals, Inc. Combination anti-selectin and immunosuppressant therapy
US20020029391A1 (en) * 1998-04-15 2002-03-07 Claude Geoffrey Davis Epitope-driven human antibody production and gene expression profiling
US6228360B1 (en) * 1998-08-19 2001-05-08 Ajinomoto Co., Inc. Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody
MY148646A (en) * 2004-05-10 2013-05-15 Abgenomics Cooperatief Ua Anti-psgl-1 antibodies
RU2262703C1 (en) * 2004-09-24 2005-10-20 Общество с ограниченной ответственностью НПО "Диагностические системы" Method for preparing control sample used in immunoenzyme analysis
EP3056568B1 (en) 2006-03-31 2021-09-15 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
EP2047863B1 (en) 2006-06-08 2013-07-31 Chugai Seiyaku Kabushiki Kaisha Preventive or remedy for inflammatory disease
JP5334319B2 (en) 2007-09-26 2013-11-06 中外製薬株式会社 Method for modifying isoelectric point of antibody by amino acid substitution of CDR
KR102339457B1 (en) 2007-09-26 2021-12-14 추가이 세이야쿠 가부시키가이샤 Modified antibody constant region
EP2241332A4 (en) 2007-12-05 2011-01-26 Chugai Pharmaceutical Co Ltd Therapeutic agent for pruritus
KR101840994B1 (en) 2007-12-05 2018-03-21 추가이 세이야쿠 가부시키가이샤 Anti-NR10 antibody and use thereof
NZ623716A (en) 2008-04-11 2016-04-29 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
KR20160062207A (en) * 2008-12-05 2016-06-01 추가이 세이야쿠 가부시키가이샤 Anti-NR10 antibody and use thereof
JP2010210772A (en) * 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd Method of manufacturing liquid crystal display device
WO2010107109A1 (en) 2009-03-19 2010-09-23 中外製薬株式会社 Antibody constant region variant
EP2409991B1 (en) 2009-03-19 2017-05-03 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
EP2597945B1 (en) * 2010-07-26 2020-07-22 Trianni, Inc. Transgenic animals and methods of use
MY172618A (en) 2010-08-02 2019-12-06 Regeneron Pharma Mice that make binding proteins comprising vl domains
CN107973851A (en) 2010-11-30 2018-05-01 中外制药株式会社 The antigen binding molecules of combination are repeated with polymolecular antigen
CN108939067A (en) * 2010-12-21 2018-12-07 瑟莱克斯制药公司 Anti- palatelet-selectin antibody and its use and identification method
SI4067496T1 (en) 2011-02-25 2023-07-31 Regeneron Pharmaceuticals, Inc. Adam6 mice
SG10201606158TA (en) 2011-08-05 2016-09-29 Regeneron Pharma Humanized universal light chain mice
RU2664181C2 (en) 2011-12-20 2018-08-15 Регенерон Фармасьютикалз, Инк. Humanised light chain mice
NZ703689A (en) 2012-06-12 2016-05-27 Regeneron Pharma Humanized non-human animals with restricted immunoglobulin heavy chain loci
RU2016141123A (en) 2014-03-21 2018-04-23 Регенерон Фармасьютикалз, Инк. VL ANTIGEN-BINDING PROTEINS MANIFESTING VARIOUS BINDING CHARACTERISTICS
AU2015230938C1 (en) 2014-03-21 2021-10-14 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
US11111314B2 (en) 2015-03-19 2021-09-07 Regeneron Pharmaceuticals, Inc. Non-human animals that select for light chain variable regions that bind antigen
WO2016167263A1 (en) 2015-04-14 2016-10-20 中外製薬株式会社 Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient
JP6845973B1 (en) 2019-11-20 2021-03-24 中外製薬株式会社 Antibody-containing preparation
WO2024194605A1 (en) 2023-03-17 2024-09-26 Quell Therapeutics Limited Treg therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
NZ236792A (en) * 1990-01-19 1993-05-26 Merck & Co Inc Recombinant human anti-cd18 antibody, murine 1b4 heavy or light chain variable region, dna, vectors, mammalian host and pharmaceutical compositions
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
GB9109645D0 (en) * 1991-05-03 1991-06-26 Celltech Ltd Recombinant antibodies

Also Published As

Publication number Publication date
FI952658A7 (en) 1995-05-31
JPH08503617A (en) 1996-04-23
RU2151612C1 (en) 2000-06-27
AU5732794A (en) 1994-06-22
CZ140195A3 (en) 1996-06-12
PL309249A1 (en) 1995-10-02
AU689090B2 (en) 1998-03-26
NO952160D0 (en) 1995-05-31
HUT71790A (en) 1996-02-28
NO952160L (en) 1995-07-31
CA2149025A1 (en) 1994-06-09
HU9501564D0 (en) 1995-07-28
FI952658L (en) 1995-05-31
KR100371784B1 (en) 2003-07-22
EP0671951A4 (en) 1997-05-21
EP0671951A1 (en) 1995-09-20
WO1994012215A1 (en) 1994-06-09

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