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CA2253834A1 - Polypeptides du type b. burgdorferi exprimes in vivo - Google Patents

Polypeptides du type b. burgdorferi exprimes in vivo Download PDF

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Publication number
CA2253834A1
CA2253834A1 CA002253834A CA2253834A CA2253834A1 CA 2253834 A1 CA2253834 A1 CA 2253834A1 CA 002253834 A CA002253834 A CA 002253834A CA 2253834 A CA2253834 A CA 2253834A CA 2253834 A1 CA2253834 A1 CA 2253834A1
Authority
CA
Canada
Prior art keywords
burgdorferi
polypeptide
polypeptides
lys
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002253834A
Other languages
English (en)
Inventor
Erol Fikrig
Kyoungho Suk
Stephen W. Barthold
Richard A. Flavell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2253834A1 publication Critical patent/CA2253834A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1207—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention porte: sur des procédés et compositions servant à la prévention, au traitement et au diagnostic de la maladie de Lyme; sur de nouveaux polypeptides du type B. burgdorferi, leurs variantes sérotypiques, leurs fragments et leurs dérivés; sur des protéines de fusion et des protéines multimères les incluant; sur des vaccins à plusieurs composants contenant les nouveaux polypeptides du type B. burgdorferi, ainsi que d'autres polypeptides immunogènes du type B. burgdorferi; sur des séquences d'ADN, des molécules d'ADN de recombinaison et des cellules hôtes transformées utiles dans les procédés et compositions ci-dessus; sur des anticorps dirigés contre les nouveaux polypeptides du type B. burgdorferi et des trousses de diagnostic comportant lesdits polypeptides ou anticorps; et sur une méthode d'identification de gènes de bactéries exprimés sélectivement in vivo.
CA002253834A 1996-05-08 1996-05-08 Polypeptides du type b. burgdorferi exprimes in vivo Abandoned CA2253834A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/006610 WO1997042325A1 (fr) 1996-05-08 1996-05-08 Polypeptides du type b. burgdorferi exprimes in vivo

Publications (1)

Publication Number Publication Date
CA2253834A1 true CA2253834A1 (fr) 1997-11-13

Family

ID=22255070

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002253834A Abandoned CA2253834A1 (fr) 1996-05-08 1996-05-08 Polypeptides du type b. burgdorferi exprimes in vivo

Country Status (4)

Country Link
EP (1) EP0915977A1 (fr)
JP (1) JP2000510339A (fr)
CA (1) CA2253834A1 (fr)
WO (1) WO1997042325A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2283494A1 (fr) * 1998-01-08 1999-07-15 Biomerieux, Inc. P37/flaa de recombinaison en tant que reactif pour diagnostic
DE19960113A1 (de) * 1999-12-08 2001-06-13 Wita Proteomics Ag Mittel und Verfahren zur Diagnose von Lyme Borreliose sowie Borreliose-Impfstoff
FI112544B (fi) * 2001-11-26 2003-12-15 Bortech Oy Menetelmä varhais- ja myöhäisvaiheen Lymen borrelioosin diagnosoimiseksi

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) * 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser

Also Published As

Publication number Publication date
WO1997042325A1 (fr) 1997-11-13
JP2000510339A (ja) 2000-08-15
EP0915977A1 (fr) 1999-05-19

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued