CA2199250A1 - Estrogens and parathyroid hormone for treating osteoporosis - Google Patents

Estrogens and parathyroid hormone for treating osteoporosis

Info

Publication number: CA2199250A1
Authority: CA; Canada
Prior art keywords: bone; osteoporosis; estrogen; parathyroid hormone; subject
Prior art date: 1994-09-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002199250A

Other languages

English (en)

French (fr)

Inventor

John Althorp Bevan

Ann Dunbar Geddes

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Procter and Gamble Co

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-09

Filing date

1995-09-06

Publication date

1996-03-14

1995-09-06 Application filed by Individual filed Critical Individual

1996-03-14 Publication of CA2199250A1 publication Critical patent/CA2199250A1/en

Status Abandoned legal-status Critical Current

Links

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239000008103 glucose Substances 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
230000036541 health Effects 0.000 description 1
102000058004 human PTH Human genes 0.000 description 1
201000000916 idiopathic juvenile osteoporosis Diseases 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
230000003993 interaction Effects 0.000 description 1
238000001990 intravenous administration Methods 0.000 description 1
238000010253 intravenous injection Methods 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000002960 lipid emulsion Substances 0.000 description 1
239000002502 liposome Substances 0.000 description 1
239000007788 liquid Substances 0.000 description 1
231100000053 low toxicity Toxicity 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
239000003550 marker Substances 0.000 description 1
239000000463 material Substances 0.000 description 1
230000007721 medicinal effect Effects 0.000 description 1
230000009245 menopause Effects 0.000 description 1
208000030159 metabolic disease Diseases 0.000 description 1
230000004060 metabolic process Effects 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
230000000877 morphologic effect Effects 0.000 description 1
239000007922 nasal spray Substances 0.000 description 1
229940097496 nasal spray Drugs 0.000 description 1
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
239000004006 olive oil Substances 0.000 description 1
235000008390 olive oil Nutrition 0.000 description 1
210000002997 osteoclast Anatomy 0.000 description 1
108010073230 parathyroid hormone (1-38) Proteins 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
229960001298 polyestradiol phosphate Drugs 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920005862 polyol Polymers 0.000 description 1
150000003077 polyols Chemical class 0.000 description 1
229920001592 potato starch Polymers 0.000 description 1
239000002243 precursor Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000003623 progesteronic effect Effects 0.000 description 1
238000002601 radiography Methods 0.000 description 1
GZUITABIAKMVPG-UHFFFAOYSA-N raloxifene Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 GZUITABIAKMVPG-UHFFFAOYSA-N 0.000 description 1
229960004622 raloxifene Drugs 0.000 description 1
230000009467 reduction Effects 0.000 description 1
238000009256 replacement therapy Methods 0.000 description 1
238000011160 research Methods 0.000 description 1
239000008159 sesame oil Substances 0.000 description 1
235000011803 sesame oil Nutrition 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
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235000019333 sodium laurylsulphate Nutrition 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
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239000000600 sorbitol Substances 0.000 description 1
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235000019166 vitamin D Nutrition 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

CA002199250A 1994-09-09 1995-09-06 Estrogens and parathyroid hormone for treating osteoporosis Abandoned CA2199250A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30392694A	1994-09-09	1994-09-09
US303,926		1994-09-09

Publications (1)

Publication Number	Publication Date
CA2199250A1 true CA2199250A1 (en)	1996-03-14

Family

ID=23174293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002199250A Abandoned CA2199250A1 (en)	1994-09-09	1995-09-06	Estrogens and parathyroid hormone for treating osteoporosis

Country Status (8)

Country	Link
EP (1)	EP0804202A4 (ja)
JP (1)	JP2001503728A (ja)
KR (1)	KR970705397A (ja)
CN (1)	CN1158569A (ja)
AU (1)	AU3674895A (ja)
CA (1)	CA2199250A1 (ja)
IL (1)	IL115225A0 (ja)
WO (1)	WO1996007416A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5545635A (en) *	1995-05-23	1996-08-13	Eli Lilly And Company	Inhibiting bone loss with equilenin
SE9702401D0 (sv)	1997-06-19	1997-06-19	Astra Ab	Pharmaceutical use
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
WO2007059470A2 (en)	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
AU2009356227A1 (en)	2009-12-07	2012-06-21	Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2015057836A2 (en) *	2013-10-15	2015-04-23	The Trustees Of Columbia University In The City Of New York	Bone anabolic parathyroid hormone and parathyroid hormone related-protein analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5118667A (en) *	1991-05-03	1992-06-02	Celtrix Pharmaceuticals, Inc.	Bone growth factors and inhibitors of bone resorption for promoting bone formation
TW303299B (ja) *	1993-07-22	1997-04-21	Lilly Co Eli

1995
- 1995-09-06 CN CN95195016A patent/CN1158569A/zh active Pending
- 1995-09-06 WO PCT/US1995/011386 patent/WO1996007416A1/en active IP Right Grant
- 1995-09-06 EP EP95934405A patent/EP0804202A4/en not_active Withdrawn
- 1995-09-06 JP JP50968396A patent/JP2001503728A/ja active Pending
- 1995-09-06 AU AU36748/95A patent/AU3674895A/en not_active Abandoned
- 1995-09-06 CA CA002199250A patent/CA2199250A1/en not_active Abandoned
- 1995-09-06 KR KR1019970701533A patent/KR970705397A/ko active IP Right Grant
- 1995-09-08 IL IL11522595A patent/IL115225A0/xx unknown

Also Published As

Publication number	Publication date
KR970705397A (ko)	1997-10-09
EP0804202A1 (en)	1997-11-05
CN1158569A (zh)	1997-09-03
EP0804202A4 (en)	1999-01-13
AU3674895A (en)	1996-03-27
WO1996007416A1 (en)	1996-03-14
JP2001503728A (ja)	2001-03-21
IL115225A0 (en)	1995-12-31

Publication	Publication Date	Title
Hay	1995	Bone disease in cholestatic liver disease
Cosman et al.	2013	Parathyroid hormone treatment for osteoporosis
RU2112515C1 (ru)	1998-06-10	Способ лечения остеопороза
Lane et al.	1998	The science and therapy of glucocorticoid-induced bone loss
Vandeweghe et al.	1993	Short and long‐term effects of growth hormone treatment on bone turnover and bone mineral content in adult growth hormone‐deficient males
Lane	2001	An update on glucocorticoid-induced osteoporosis
JP2531505B2 (ja)	1996-09-04	骨質量増加用医薬複合剤の投与用キット
DE69201725T2 (de)	1996-04-18	Behandlungsmethoden für osteoporose.
CZ301017B6 (cs)	2009-10-14	Lécivo pro snížení rizika vertebrální nebo nevertebrální zlomeniny kosti u cloveka a rizika osteoporózy
Combe et al.	1997	Equivalence of nasal spray and subcutaneous formulations of salmon calcitonin
Mitchell et al.	1990	Glucocorticoid-induced osteoporosis: mechanisms for bone loss; evaluation of strategies for prevention
EP1221966B1 (en)	2005-11-16	Use of a parathyroid hormone for reducing the risk of cancer
CA2199250A1 (en)	1996-03-14	Estrogens and parathyroid hormone for treating osteoporosis
AU686458B2 (en)	1998-02-05	Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone
WO1999004808A1 (fr)	1999-02-04	Medicaments dentaires contenant de la pth
Cascella et al.	2005	Effects of neridronate treatment in elderly women with osteoporosis
AU686019B2 (en)	1998-01-29	Phosphonates and parathyroid hormone for osteoporosis
JPH0873376A (ja)	1996-03-19	骨粗鬆症治療薬
Manuele et al.	2007	The teriparatide in the treatment of severe senile osteoporosis
Zahid et al.	2020	Efficacy of Bisphosphonates and Recombinant Parathyroid Hormone in Treatment of Osteoporosis in Pakistan
Rittinghaus et al.	1990	The concept and treatment of osteoporosis
Seymour et al.	1994	Prospects for treating osteoporosis in older people
US20160339063A1 (en)	2016-11-24	Composition for preventing and healing compromised bone and a method of making same
JPH1192395A (ja)	1999-04-06	Ｐｔｈを含有する歯科治療剤
CZ20004679A3 (cs)	2001-05-16	Terapeutické kombinace (selektivních) modulátorů estrogenního receptoru (ŠERM) a prostředků podporujících sekreci růstového hormonu (GHS) pro léčbu muskuloskeletární fragility

Legal Events

Date	Code	Title	Description
1997-03-05	EEER	Examination request
2001-04-30	FZDE	Discontinued