CA2167706A1 - Modified dna virus vectors and uses therefor - Google Patents
Modified dna virus vectors and uses thereforInfo
- Publication number
- CA2167706A1 CA2167706A1 CA 2167706 CA2167706A CA2167706A1 CA 2167706 A1 CA2167706 A1 CA 2167706A1 CA 2167706 CA2167706 CA 2167706 CA 2167706 A CA2167706 A CA 2167706A CA 2167706 A1 CA2167706 A1 CA 2167706A1
- Authority
- CA
- Canada
- Prior art keywords
- virus
- restriction enzyme
- site
- cassette
- unique
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
- C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9796593A | 1993-07-27 | 1993-07-27 | |
US08/097,965 | 1993-07-27 | ||
US26723194A | 1994-06-29 | 1994-06-29 | |
US08/267,231 | 1994-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2167706A1 true CA2167706A1 (en) | 1995-02-09 |
Family
ID=26793823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2167706 Abandoned CA2167706A1 (en) | 1993-07-27 | 1994-07-22 | Modified dna virus vectors and uses therefor |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0722493A1 (ja) |
JP (1) | JPH09501564A (ja) |
CA (1) | CA2167706A1 (ja) |
WO (1) | WO1995004139A1 (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763217A (en) * | 1993-11-10 | 1998-06-09 | University Of British Columbia | Method of using, process of preparing and composition comprising recombinant herpesvirus vectors |
US6544523B1 (en) | 1996-11-13 | 2003-04-08 | Chiron Corporation | Mutant forms of Fas ligand and uses thereof |
US5998174A (en) * | 1997-05-12 | 1999-12-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Multigene vectors |
EP2386629A1 (en) | 1997-10-14 | 2011-11-16 | Darwin Molecular Corporation | Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities |
BR9813930A (pt) | 1997-11-06 | 2006-12-19 | Chiron Spa | antìgeno neisserial |
WO1999036544A2 (en) | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Neisseria meningitidis antigens |
CN101293920B (zh) | 1998-05-01 | 2012-07-18 | 诺华疫苗和诊断公司 | 脑膜炎奈瑟球菌抗原和组合物 |
JP2003518363A (ja) | 1999-04-30 | 2003-06-10 | カイロン エセ.ピー.アー. | 保存されたナイセリア抗原 |
GB9911683D0 (en) | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
DK1801219T3 (en) | 1999-10-29 | 2015-12-07 | Glaxosmithkline Biolog Sa | Neisseriale antigenic peptides. |
ES2588917T3 (es) | 2000-01-17 | 2016-11-07 | Glaxosmithkline Biologicals Sa | Vacuna de VME suplementada contra meningococo |
EP1950297A2 (en) | 2000-05-31 | 2008-07-30 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers |
AU2002214127B2 (en) | 2000-10-27 | 2007-06-07 | J. Craig Venter Institute, Inc. | Nucleic acids and proteins from streptococcus groups A and B |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
NZ546711A (en) | 2001-12-12 | 2008-06-30 | Chiron Srl | Immunisation against chlamydia trachomatis |
ATE466875T1 (de) | 2002-11-15 | 2010-05-15 | Novartis Vaccines & Diagnostic | Unerwartete oberflächenproteine in neisseria meningitidis |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
WO2005049846A2 (en) | 2003-11-17 | 2005-06-02 | Crusade Laboratories Limited | Mutant herpes simplex virus and use thereof in the treatment of squamous cell cancer |
US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
GB0326798D0 (en) | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
KR20120126130A (ko) | 2004-03-29 | 2012-11-20 | 가르파마 컴퍼니 리미티드 | 신규 갈렉틴 9 개변체 단백질 및 그 용도 |
EP2054431B1 (en) | 2006-06-09 | 2011-08-31 | Novartis AG | Conformers of bacterial adhesins |
EP4179085A1 (en) * | 2020-07-07 | 2023-05-17 | Oriengene Biotechnology Ltd | Guide rna for hsv-1 gene editing and method thereof |
-
1994
- 1994-07-22 EP EP94925681A patent/EP0722493A1/en not_active Withdrawn
- 1994-07-22 JP JP7505891A patent/JPH09501564A/ja active Pending
- 1994-07-22 CA CA 2167706 patent/CA2167706A1/en not_active Abandoned
- 1994-07-22 WO PCT/US1994/008243 patent/WO1995004139A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH09501564A (ja) | 1997-02-18 |
EP0722493A1 (en) | 1996-07-24 |
WO1995004139A1 (en) | 1995-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2167706A1 (en) | Modified dna virus vectors and uses therefor | |
US5837532A (en) | Herpes simplex cirus type 1 mutant | |
US6719982B1 (en) | Mutant herpes simplex viruses and uses thereof | |
Fraefel et al. | Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells | |
US5849571A (en) | Latency active herpes virus promoters and their use | |
US5763217A (en) | Method of using, process of preparing and composition comprising recombinant herpesvirus vectors | |
Lachmann et al. | Utilization of the herpes simplex virus type 1 latency-associated regulatory region to drive stable reporter gene expression in the nervous system | |
EP0176170B1 (en) | Herpes simplex virus as a vector | |
US20020028925A1 (en) | Hsv viral vector | |
Fisher et al. | Isolation and characterisation of herpes simplex virus type 1 mutants which fail to induce dUTPase activity | |
Jones et al. | Analysis of the transcriptional promoter which regulates the latency-related transcript of bovine herpesvirus 1 | |
AU3700797A (en) | Hsv strain lacking functional icp27 and icp34.5 genes | |
KR20220016150A (ko) | 재조합 헤르페스비랄레스 벡터 | |
KR100507399B1 (ko) | 진핵생물의 유전자 발현 카세트 및 그의 용도 | |
Rinaldi et al. | A non-cytotoxic herpes simplex virus vector which expresses Cre recombinase directs efficient site specific recombination | |
WO1999060145A1 (en) | Mutant herpes simplex viruses and uses thereof | |
JP2002526039A (ja) | 突然変異ヘルペスウイルスを増殖するための細胞系 | |
Johnson et al. | Replication-defective recombinant herpes simplex virus vectors | |
AU760308B2 (en) | Latency-active regulatory sequences of herpesviruses and latency-inactive herpesviruses for gene transfer | |
Fuchs et al. | A novel intergenic site for integration and expression of foreign genes in the genome of pseudorabies virus |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |