CA1312279C - Sterile blood component collection - Google Patents
Sterile blood component collectionInfo
- Publication number
- CA1312279C CA1312279C CA000575655A CA575655A CA1312279C CA 1312279 C CA1312279 C CA 1312279C CA 000575655 A CA000575655 A CA 000575655A CA 575655 A CA575655 A CA 575655A CA 1312279 C CA1312279 C CA 1312279C
- Authority
- CA
- Canada
- Prior art keywords
- solution
- blood
- supply
- bacteria
- supply line
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7518—General characteristics of the apparatus with filters bacterial
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
Abstract
Abstract of the Disclosure Apparatus for collecting blood components including a supply line that is connected to a blood line and has a filt-er on it to permit passage of supply solution (e.g., anticoagu-lant or saline prime) and blocks passage of bacteria.
Description
13122~
STERILE BLOOD COMPONENT COLLECTION
~ield of the Invention The invention relates to apparatus for col~ecting components from a donor's blood.
Background of the Invention In blood component separation and collection appa~
ratus, for example, a centrifuge, it is desired to prevent the introduction of bacteria into the collection bags for the blood components separated from a donor's blood. In at least some prior blood centriEuge systems, a disposable tub-ing set for use with each donor includes anticoagulant and saline primtng solutions in bags preconnected to the blood supply line.
Summary of the Invention . _ It has been discovered that a supply solution (e.-g., anticoagulant or saline prime) could be supplied to a blood flow line from a donor in a manner to maintain a sterile system by providing a filter in the supply line to permit passage of the supply solution and block passage of bacteria.
In preferred embodiments the supply line has a con-nector upstream of the filter for connection to a source of supply solution; the connector has a needle for piercing a bag of supply solution; the filter includes a membrane with a maximum pore size to prevent passage of bacteria; and the bloo~ flow line is connected to a separation channel of a centrifuge having an outlet line connected to a platelet col-lection bag.
Other advantages and features of the invention will be apparent from the following description of a preferred em-bodiment thereof and from the claims.
Description of the Preferred Embodiment _ The preferred embodiment will now ba described.
~3~227~
STERILE BLOOD COMPONENT COLLECTION
~ield of the Invention The invention relates to apparatus for col~ecting components from a donor's blood.
Background of the Invention In blood component separation and collection appa~
ratus, for example, a centrifuge, it is desired to prevent the introduction of bacteria into the collection bags for the blood components separated from a donor's blood. In at least some prior blood centriEuge systems, a disposable tub-ing set for use with each donor includes anticoagulant and saline primtng solutions in bags preconnected to the blood supply line.
Summary of the Invention . _ It has been discovered that a supply solution (e.-g., anticoagulant or saline prime) could be supplied to a blood flow line from a donor in a manner to maintain a sterile system by providing a filter in the supply line to permit passage of the supply solution and block passage of bacteria.
In preferred embodiments the supply line has a con-nector upstream of the filter for connection to a source of supply solution; the connector has a needle for piercing a bag of supply solution; the filter includes a membrane with a maximum pore size to prevent passage of bacteria; and the bloo~ flow line is connected to a separation channel of a centrifuge having an outlet line connected to a platelet col-lection bag.
Other advantages and features of the invention will be apparent from the following description of a preferred em-bodiment thereof and from the claims.
Description of the Preferred Embodiment _ The preferred embodiment will now ba described.
~3~227~
Drawings Figure 1 is a diagram of platelet collection apparatus according to the invention.
Figure 2 is an exploded perspective view of a filter of the Figure 1 apparatus.
Figure 3 is an e~ploded elevation o~ a connector of the Figure 1 apparatus.
Structure Referring to Figure 1, there is shown pla~elet collec-tion apparatus 10, including blood supply line 12, centrifuge 14 and outlet tubes 16, 18, 20. Anticoagulant supply bag 22 is con-nected to blood supply line 12 via supply line 24, llaving filter 26 on it and connected to anticoagulant bag 22 by connector 28~
Outlet tube 20 is connected to platelet collection bag 30. Centri-fuge 14 includes a rotating bowl that receives a disposable channel connected to tubes 12, 16, 18, 20 and is similar to the centri~uge apparatus described in Kellogg et al. United States Patent No. 4,387,848. Tubes 12, 16, 18, 20 are connected to the channel by a seal-less multichannel rotation connection means of the type shown in United States Patent No. 4,146,172, maintaining the closed, bacteria-free system.
Referring to Figure 2, it is seen that filter 26 in-cludes upper housing 32 with inlet 34, lower housing 36 with out-let 38 and microporous membrane 40 therebetween. Filter 26 is B available from Gelman Filters. Membrane 40 (available under the trade designation ~-ERSAPOR 200) has a 0.2 micron pore size. Upper -rî c-d~ r~
~3~ 2~79 - 2a - 69204-163 housing 32 also has bent holes 42 covered by membranes 44 carried on the lower surface of housing 32. ~ower housing 36 has ribs 46 to support membrane 40 and to proviae drainage channels between them directed into the opening to outlet 38.
~ 3~ 2279 Referring to Fig. 3, connector 28 includes needle 48, having sharp pointed end 50 for piercing a wall of bag 22 and fluid flow passage 52 therein. Needle 48 1S connecced to clear plastic drip chamber 54 having fluid level indicia 56. Cap 58 is removably connectable-to cover a vent hole in base 60, form-ed integrally with needle 48. Cover 62 covers needle 48.
Apparatus 10 also includes a supply bag of saline prime solution connected to blood flow line 12 by a filter and supply tube (all not shown) similar to that for anticoagulant.
Operation In operation~ when centrifuge 14 is used with a new donor, a sterile tubing set including tubes 12, 16, 18, 20, 24 and a centrifuge channel (not shown) is mounted on centri-fuge 14J and conn~ctor 28 is connected to anticoagulant bag 22 15 by puncturing bag 22 with needla 48 after removing needle cover 62. A sterile saline prime solution bag (not shown) is con-nected in a similar manner. During the removal of cover 62 and the connection of connector 28 to bag 22, it is possible that the hydraulic system is exposed to bacteria-at connector 28.
20 Any bacteria introduced into connector 28 are preventPd from going past filter 26, owing to the pore size of membrane 40.
Bacteria are thus prevented from being transported to platelet collection bag 30, where they could otherwise multiply during storage of the platelets. By providing filters and connectors 25 on the tubing set, the supplies of anticoagulant and sterile solution can be shipped and stored separately from the tubinK
set~ simplifyingshipping, storage, and handling of the tubing set. In addition, different fluids and different bag volumes can be selected, depending upon a particular donor's need, and the solutions and tubing set can each be separately sterilized by a method most appropriate for each.
Puncturing needle 48 can be used multiple times dur-ing a given procedure to connect multiple bags. Thus the amounts ~3~ 227~
of both saline and anticoagulant that are actually needed can be provided. This ls ~-m advantage over permanently connected bags, which elther limit the procedure to the amount of solu-tion preconnected or tend to oversize the amount of fluid furnished with the set, which leads to both higher weights and wastage of fluid. This feature also permits flexibility to extend a procedure that is not proceeding as quickly as expect-ed in terms of collection. The procedure can be extended until the desired amount of blood components have been collected, add-ing a new bag of antlcoagulant as needed.
Other Embodiments Other embodiments of the invention are within thescope of the following claims.
For example, other blood separators besides centri-fuge 14 can be used, and the invention is applicable to collect-ing other blood components.
Claims What is claimed is:
Figure 2 is an exploded perspective view of a filter of the Figure 1 apparatus.
Figure 3 is an e~ploded elevation o~ a connector of the Figure 1 apparatus.
Structure Referring to Figure 1, there is shown pla~elet collec-tion apparatus 10, including blood supply line 12, centrifuge 14 and outlet tubes 16, 18, 20. Anticoagulant supply bag 22 is con-nected to blood supply line 12 via supply line 24, llaving filter 26 on it and connected to anticoagulant bag 22 by connector 28~
Outlet tube 20 is connected to platelet collection bag 30. Centri-fuge 14 includes a rotating bowl that receives a disposable channel connected to tubes 12, 16, 18, 20 and is similar to the centri~uge apparatus described in Kellogg et al. United States Patent No. 4,387,848. Tubes 12, 16, 18, 20 are connected to the channel by a seal-less multichannel rotation connection means of the type shown in United States Patent No. 4,146,172, maintaining the closed, bacteria-free system.
Referring to Figure 2, it is seen that filter 26 in-cludes upper housing 32 with inlet 34, lower housing 36 with out-let 38 and microporous membrane 40 therebetween. Filter 26 is B available from Gelman Filters. Membrane 40 (available under the trade designation ~-ERSAPOR 200) has a 0.2 micron pore size. Upper -rî c-d~ r~
~3~ 2~79 - 2a - 69204-163 housing 32 also has bent holes 42 covered by membranes 44 carried on the lower surface of housing 32. ~ower housing 36 has ribs 46 to support membrane 40 and to proviae drainage channels between them directed into the opening to outlet 38.
~ 3~ 2279 Referring to Fig. 3, connector 28 includes needle 48, having sharp pointed end 50 for piercing a wall of bag 22 and fluid flow passage 52 therein. Needle 48 1S connecced to clear plastic drip chamber 54 having fluid level indicia 56. Cap 58 is removably connectable-to cover a vent hole in base 60, form-ed integrally with needle 48. Cover 62 covers needle 48.
Apparatus 10 also includes a supply bag of saline prime solution connected to blood flow line 12 by a filter and supply tube (all not shown) similar to that for anticoagulant.
Operation In operation~ when centrifuge 14 is used with a new donor, a sterile tubing set including tubes 12, 16, 18, 20, 24 and a centrifuge channel (not shown) is mounted on centri-fuge 14J and conn~ctor 28 is connected to anticoagulant bag 22 15 by puncturing bag 22 with needla 48 after removing needle cover 62. A sterile saline prime solution bag (not shown) is con-nected in a similar manner. During the removal of cover 62 and the connection of connector 28 to bag 22, it is possible that the hydraulic system is exposed to bacteria-at connector 28.
20 Any bacteria introduced into connector 28 are preventPd from going past filter 26, owing to the pore size of membrane 40.
Bacteria are thus prevented from being transported to platelet collection bag 30, where they could otherwise multiply during storage of the platelets. By providing filters and connectors 25 on the tubing set, the supplies of anticoagulant and sterile solution can be shipped and stored separately from the tubinK
set~ simplifyingshipping, storage, and handling of the tubing set. In addition, different fluids and different bag volumes can be selected, depending upon a particular donor's need, and the solutions and tubing set can each be separately sterilized by a method most appropriate for each.
Puncturing needle 48 can be used multiple times dur-ing a given procedure to connect multiple bags. Thus the amounts ~3~ 227~
of both saline and anticoagulant that are actually needed can be provided. This ls ~-m advantage over permanently connected bags, which elther limit the procedure to the amount of solu-tion preconnected or tend to oversize the amount of fluid furnished with the set, which leads to both higher weights and wastage of fluid. This feature also permits flexibility to extend a procedure that is not proceeding as quickly as expect-ed in terms of collection. The procedure can be extended until the desired amount of blood components have been collected, add-ing a new bag of antlcoagulant as needed.
Other Embodiments Other embodiments of the invention are within thescope of the following claims.
For example, other blood separators besides centri-fuge 14 can be used, and the invention is applicable to collect-ing other blood components.
Claims What is claimed is:
Claims (9)
1. Apparatus for collecting blood components com-prising a sterile fluid flow line for receiving blood from a donor, a blood separator connector to said flow line, a blood component collection container connected to said separator, a first supply line connected at one end to supply solution to said sterile fluid flow line, and a first filter on said supply line that permits pas-sage of solution and blocks passage of bacteria.
2. The apparatus of claim 1 wherein the other end of said supply line is connected to a connector adapted to be connected to a source of solution.
3. The apparatus of claim 2 wherein said connector includes a needle for puncturing a wall of a source of supply solution.
4. The apparatus of claim 1 wherein said filter comprises a membrane having a maximum pore size to prevent passage of bacteria.
5. The apparatus of claim 1 wherein said supply solution is anticoagulant or saline prime solution.
6. The apparatus of claim 1 wherein said blood separator is a centrifuge.
7. The apparatus of claim 3 wherein said connector has a drip chamber attached to it.
8. The apparatus of claim 1 wherein said blood com-ponent collection container is a platelet collection bag.
9. The apparatus of claim 1 further comprising a second supply line connected at one end to supply solution to said sterile fluid flow line and a second filter on said supply line that permits passage of solution and blocks passage of bacteria.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US089,493 | 1979-10-30 | ||
| US8949387A | 1987-08-26 | 1987-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1312279C true CA1312279C (en) | 1993-01-05 |
Family
ID=22217946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000575655A Expired - Lifetime CA1312279C (en) | 1987-08-26 | 1988-08-25 | Sterile blood component collection |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPH0667403B2 (en) |
| AU (1) | AU587949B2 (en) |
| CA (1) | CA1312279C (en) |
| DE (1) | DE3828903A1 (en) |
| FR (1) | FR2619721B1 (en) |
| GB (1) | GB2208997B (en) |
| IT (1) | IT1234207B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5092996A (en) * | 1991-02-19 | 1992-03-03 | Miles Inc. | Blood filtering system |
| US6653026B2 (en) | 2000-12-20 | 2003-11-25 | Numerical Technologies, Inc. | Structure and method of correcting proximity effects in a tri-tone attenuated phase-shifting mask |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4086924A (en) * | 1976-10-06 | 1978-05-02 | Haemonetics Corporation | Plasmapheresis apparatus |
| US4197847A (en) * | 1977-03-31 | 1980-04-15 | Isaac Djerassi | Method and apparatus for collecting transfusable granulocytes |
| US4200095A (en) * | 1977-08-15 | 1980-04-29 | Millipore Corporation | Arrangement for intravenous administration or the like |
| US4387848A (en) * | 1977-10-03 | 1983-06-14 | International Business Machines Corporation | Centrifuge assembly |
| US4146172A (en) * | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
| US4360435A (en) * | 1979-11-01 | 1982-11-23 | Baxter Travenol Laboratories, Inc. | Process for sterilizing and transferring a solution |
| US4311587A (en) * | 1979-12-10 | 1982-01-19 | Japan Foundation For Artificial Organs | Filter arrangement denying bacteria entry to peritoneum |
| US4309992A (en) * | 1980-07-11 | 1982-01-12 | Dodak Michael J | Microbicidal filter |
| AU8565682A (en) * | 1981-07-09 | 1983-01-13 | Haemonetics Corporation | Centrifugal blood fractionation |
| US4440207A (en) * | 1982-05-14 | 1984-04-03 | Baxter Travenol Laboratories, Inc. | Antibacterial protective cap for connectors |
| JPS59214457A (en) * | 1983-05-20 | 1984-12-04 | 日立工機株式会社 | Blood component sampling apparatus |
| DE8406463U1 (en) * | 1984-03-02 | 1984-06-14 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | DEVICE FOR BLOOD SEPARATION AND TREATMENT AND STORAGE OF BLOOD AND BLOOD COMPONENTS |
| DE3683925D1 (en) * | 1985-02-26 | 1992-03-26 | Baxter Int | TRANSFER SYSTEM FOR FLUIDS. |
| JPS61257203A (en) * | 1985-05-10 | 1986-11-14 | Terumo Corp | Hydrophilic porous membrane and its preparation |
| GB8521867D0 (en) * | 1985-09-03 | 1985-10-09 | Fisons Plc | Centrifuge |
| US4678458A (en) * | 1986-06-09 | 1987-07-07 | Fredeking Terry M | Method for avoiding mistakes during plasmapheresis |
| JPS63139559A (en) * | 1986-12-03 | 1988-06-11 | 川澄化学工業株式会社 | Blood component separation bag apparatus |
| JP2577940B2 (en) * | 1987-02-25 | 1997-02-05 | バクスター、インターナショナル、インコーポレイテッド | Purging system for blood tube network |
-
1988
- 1988-08-19 AU AU21124/88A patent/AU587949B2/en not_active Ceased
- 1988-08-25 CA CA000575655A patent/CA1312279C/en not_active Expired - Lifetime
- 1988-08-25 DE DE3828903A patent/DE3828903A1/en active Granted
- 1988-08-25 GB GB8820147A patent/GB2208997B/en not_active Expired - Lifetime
- 1988-08-25 IT IT8867776A patent/IT1234207B/en active
- 1988-08-26 FR FR8811273A patent/FR2619721B1/en not_active Expired - Lifetime
- 1988-08-26 JP JP63212288A patent/JPH0667403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB2208997A (en) | 1989-04-26 |
| JPH0667403B2 (en) | 1994-08-31 |
| GB8820147D0 (en) | 1988-09-28 |
| IT1234207B (en) | 1992-05-06 |
| AU2112488A (en) | 1989-03-02 |
| GB2208997B (en) | 1991-03-13 |
| AU587949B2 (en) | 1989-08-31 |
| DE3828903C2 (en) | 1992-06-25 |
| FR2619721A1 (en) | 1989-03-03 |
| JPH01145065A (en) | 1989-06-07 |
| DE3828903A1 (en) | 1989-03-16 |
| FR2619721B1 (en) | 1997-10-31 |
| IT8867776A0 (en) | 1988-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4978446A (en) | Sterile blood component collection | |
| US5738796A (en) | Method for separating components from a biological fluid | |
| US5407425A (en) | System for the collecting and retransfusion of autologous blood | |
| AU651646B2 (en) | System and method for processing biological fluids | |
| CA2063790C (en) | Biological fluid processing | |
| US5423738A (en) | Blood pumping and processing system | |
| EP1251922B1 (en) | Cassette with integral separation device | |
| EP0348475B1 (en) | Apparatus and methods for generating platelet concentrate | |
| JP4861649B2 (en) | Blood component collection circuit and blood component collection device | |
| US5217627A (en) | System and method for processing biological fluid | |
| US4637813A (en) | Blood processing assembly including a prepackaged fluid circuit module | |
| US4772256A (en) | Methods and apparatus for autotransfusion of blood | |
| US7566315B2 (en) | Blood component collection apparatus and method | |
| US4775360A (en) | Autologus blood methods and apparatus | |
| EP0156496B1 (en) | Apparatus for the treatment of plasma | |
| CA2143680A1 (en) | Process and apparatus for removal of unwanted fluids from processed blood products | |
| JP2000512173A (en) | Blood processing system | |
| EP0299054A1 (en) | Centrifugation pheresis system. | |
| AU4055189A (en) | Blood processing systems and apparatus | |
| EP0487096B1 (en) | Single-needle extracorporeal plasmapheresis circuit | |
| JP2002538899A (en) | Apparatus and method for processing blood | |
| CA1312279C (en) | Sterile blood component collection | |
| JPH03277370A (en) | Blood component separating device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |