CA1198440A - Carbapenem antibiotics - Google Patents

Carbapenem antibiotics

Info

Publication number: CA1198440A
Authority: CA; Canada
Prior art keywords: alkyl; carbon atoms; formula; group; ring
Prior art date: 1982-04-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000424190A

Other languages

English (en)

French (fr)

Inventor

Choung U. Kim

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-08

Filing date

1983-03-22

Publication date

1985-12-24

1983-03-22 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1985-12-24 Application granted granted Critical

1985-12-24 Publication of CA1198440A publication Critical patent/CA1198440A/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CA000424190A 1982-04-08 1983-03-22 Carbapenem antibiotics Expired CA1198440A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36662782A	1982-04-08	1982-04-08
US366,627		1982-04-08

Publications (1)

Publication Number	Publication Date
CA1198440A true CA1198440A (en)	1985-12-24

Family

ID=23443823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000424190A Expired CA1198440A (en)	1982-04-08	1983-03-22	Carbapenem antibiotics

Country Status (25)

Country	Link
JP (1)	JPS58188887A (de)
KR (1)	KR880001055B1 (de)
AT (1)	AT383126B (de)
AU (1)	AU567092B2 (de)
BE (1)	BE896407A (de)
CA (1)	CA1198440A (de)
CH (1)	CH661927A5 (de)
DE (1)	DE3312517A1 (de)
DK (1)	DK155983A (de)
ES (1)	ES8405399A1 (de)
FI (1)	FI74009C (de)
FR (1)	FR2524888B1 (de)
GB (1)	GB2118183B (de)
GR (1)	GR78822B (de)
HU (1)	HU190716B (de)
IE (1)	IE55225B1 (de)
IL (1)	IL68295A0 (de)
IT (1)	IT1168854B (de)
LU (1)	LU84739A1 (de)
MY (1)	MY8700945A (de)
NL (1)	NL8301193A (de)
OA (1)	OA07395A (de)
PT (1)	PT76518B (de)
SE (1)	SE460197B (de)
ZA (1)	ZA832411B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics
AT396473B (de) *	1984-10-02	1993-09-27	Bristol Myers Squibb Co	Verfahren zur herstellung von neuen carbapenemderivaten
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU531084B2 (en) *	1977-10-19	1983-08-11	Merck & Co., Inc.	Azetidine derivatives
EP0017992A1 (de) *	1979-04-19	1980-10-29	Merck & Co. Inc.	2-Substituierte-6-substituierte-1-Carbadethiapen-2-em-3-carbonsäuren, Verfahren zu ihrer Herstellung, sie enthaltende antibiotische pharmazeutische Zusammensetzungen und Verfahren zur Herstellung von Zwischenprodukten
EP0038869A1 (de) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Verfahren zur Herstellung von 1-Carbapenemen und Zwischenprodukte für ihre Herstellung
HU185493B (en) *	1981-12-30	1985-02-28	Richter Gedeon Vegyeszet	Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1983
- 1983-03-22 CA CA000424190A patent/CA1198440A/en not_active Expired
- 1983-04-01 FR FR8305431A patent/FR2524888B1/fr not_active Expired
- 1983-04-04 KR KR1019830001386A patent/KR880001055B1/ko not_active IP Right Cessation
- 1983-04-05 NL NL8301193A patent/NL8301193A/nl not_active Application Discontinuation
- 1983-04-05 IL IL68295A patent/IL68295A0/xx not_active IP Right Cessation
- 1983-04-05 ES ES521224A patent/ES8405399A1/es not_active Expired
- 1983-04-05 ZA ZA832411A patent/ZA832411B/xx unknown
- 1983-04-05 FI FI831135A patent/FI74009C/fi not_active IP Right Cessation
- 1983-04-06 AU AU13198/83A patent/AU567092B2/en not_active Ceased
- 1983-04-07 PT PT76518A patent/PT76518B/pt not_active IP Right Cessation
- 1983-04-07 SE SE8301928A patent/SE460197B/sv not_active IP Right Cessation
- 1983-04-07 BE BE0/210512A patent/BE896407A/fr not_active IP Right Cessation
- 1983-04-07 GR GR71026A patent/GR78822B/el unknown
- 1983-04-07 IT IT48061/83A patent/IT1168854B/it active
- 1983-04-07 LU LU84739A patent/LU84739A1/fr unknown
- 1983-04-07 GB GB08309505A patent/GB2118183B/en not_active Expired
- 1983-04-07 DE DE19833312517 patent/DE3312517A1/de active Granted
- 1983-04-07 DK DK155983A patent/DK155983A/da not_active IP Right Cessation
- 1983-04-07 HU HU831201A patent/HU190716B/hu unknown
- 1983-04-07 IE IE800/83A patent/IE55225B1/en not_active IP Right Cessation
- 1983-04-08 AT AT0125583A patent/AT383126B/de not_active IP Right Cessation
- 1983-04-08 OA OA57966A patent/OA07395A/xx unknown
- 1983-04-08 JP JP58061072A patent/JPS58188887A/ja active Granted
- 1983-04-08 CH CH1915/83A patent/CH661927A5/de not_active IP Right Cessation
1987
- 1987-12-30 MY MY945/87A patent/MY8700945A/xx unknown

Also Published As

Publication number	Publication date
PT76518B (en)	1986-02-06
IE55225B1 (en)	1990-07-04
AU567092B2 (en)	1987-11-12
IT8348061A0 (it)	1983-04-07
OA07395A (fr)	1984-06-30
JPS58188887A (ja)	1983-11-04
AU1319883A (en)	1983-10-13
DK155983A (da)	1983-10-09
DE3312517C2 (de)	1991-10-31
IT1168854B (it)	1987-05-20
BE896407A (fr)	1983-10-07
ES521224A0 (es)	1984-06-01
GB2118183A (en)	1983-10-26
KR880001055B1 (ko)	1988-06-18
ATA125583A (de)	1986-10-15
IL68295A0 (en)	1983-07-31
FI74009C (fi)	1987-12-10
SE460197B (sv)	1989-09-18
FR2524888A1 (fr)	1983-10-14
FI74009B (fi)	1987-08-31
SE8301928L (sv)	1983-12-02
FR2524888B1 (fr)	1985-12-13
DK155983D0 (da)	1983-04-07
MY8700945A (en)	1987-12-31
NL8301193A (nl)	1983-11-01
PT76518A (en)	1983-05-01
CH661927A5 (de)	1987-08-31
KR840004429A (ko)	1984-10-15
FI831135A0 (fi)	1983-04-05
IE830800L (en)	1983-10-08
GB8309505D0 (en)	1983-05-11
DE3312517A1 (de)	1983-10-20
HU190716B (en)	1986-10-28
SE8301928D0 (sv)	1983-04-07
JPH0524156B2 (de)	1993-04-06
ES8405399A1 (es)	1984-06-01
FI831135L (fi)	1983-10-09
GR78822B (de)	1984-10-02
GB2118183B (en)	1985-11-27
ZA832411B (en)	1983-12-28
LU84739A1 (fr)	1983-12-05
AT383126B (de)	1987-05-25

Publication	Publication Date	Title
CA1273009A (en)	1990-08-21	Carbapenem antibiotics
CH657853A5 (de)	1986-09-30	Carbapenemderivate, deren herstellung und solche verbindungen enthaltende praeparate.
CA1142867A (en)	1983-03-15	ANTIBIOTIC .beta.-LACTAM COMPOUNDS, PRODUCTION THEREOF, AND ITS USE AS ANTIMICROBIAL AGENT
CA1283659C (en)	1991-04-30	Carbapenem antibiotics
CA1198440A (en)	1985-12-24	Carbapenem antibiotics
DE3334937C2 (de)	1991-05-02
DE69218843T2 (de)	1997-10-09	Aminooxypyrrolidinylthiocarbapenem-Verbindungen
AU598767B2 (en)	1990-07-05	Carbapenems with quaternized heterothioalkythio substitution at position 2
DE69523058T2 (de)	2002-02-07	Carbapenem-derivate
EP0235823A2 (de)	1987-09-09	Carbapenem-Antibiotika, ein Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE3630857C2 (de)	1994-04-07	Carbapenem-Antibiotika, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Mittel
CA1260945A (en)	1989-09-26	Carbapenem antibiotics
CH633800A5 (en)	1982-12-31	Process for the preparation of guanidines
AT381942B (de)	1986-12-10	Verfahren zur herstellung neuer carbapenem-derivate
AT396473B (de)	1993-09-27	Verfahren zur herstellung von neuen carbapenemderivaten
AT387574B (de)	1989-02-10	Verfahren zur herstellung neuer carbapenem-derivate
AT387388B (de)	1989-01-10	Verfahren zur herstellung von neuen carbapenem-antibiotika
DD252605A5 (de)	1987-12-23	Verfahren zur herstellung von carbapenem-antibiotika

Legal Events

Date	Code	Title	Description
2003-03-22	MKEX	Expiry