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CA1002343A - Method and apparatus for detecting and classifying nucleic acid particles - Google Patents

Method and apparatus for detecting and classifying nucleic acid particles

Info

Publication number
CA1002343A
CA1002343A CA200,800A CA200800A CA1002343A CA 1002343 A CA1002343 A CA 1002343A CA 200800 A CA200800 A CA 200800A CA 1002343 A CA1002343 A CA 1002343A
Authority
CA
Canada
Prior art keywords
detecting
nucleic acid
acid particles
classifying
classifying nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA200,800A
Other versions
CA200800S (en
Inventor
Tomas Hirschfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Block Engineering Inc
Original Assignee
Block Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Block Engineering Inc filed Critical Block Engineering Inc
Application granted granted Critical
Publication of CA1002343A publication Critical patent/CA1002343A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA200,800A 1973-07-02 1974-05-24 Method and apparatus for detecting and classifying nucleic acid particles Expired CA1002343A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US375807A US3872312A (en) 1973-07-02 1973-07-02 Method and apparatus for detecting and classifying nucleic acid particles

Publications (1)

Publication Number Publication Date
CA1002343A true CA1002343A (en) 1976-12-28

Family

ID=23482435

Family Applications (1)

Application Number Title Priority Date Filing Date
CA200,800A Expired CA1002343A (en) 1973-07-02 1974-05-24 Method and apparatus for detecting and classifying nucleic acid particles

Country Status (9)

Country Link
US (1) US3872312A (en)
JP (1) JPS5050093A (en)
AU (1) AU476320B2 (en)
CA (1) CA1002343A (en)
CH (1) CH582882A5 (en)
DE (1) DE2431203A1 (en)
FR (1) FR2236180B1 (en)
GB (1) GB1452231A (en)
NL (1) NL7407776A (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571388A (en) * 1983-01-24 1986-02-18 Becton Dickinson And Company Detection of reticulocytes
NZ207393A (en) * 1983-08-05 1987-03-31 Neal Lloyd First Staining dna in living cells
SE455646B (en) * 1984-10-22 1988-07-25 Radians Innova Ab FLUORESCENT DEVICE
US4707451A (en) * 1985-09-18 1987-11-17 Becton, Dickinson And Company Detection of reticulocytes
US4883867A (en) * 1985-11-01 1989-11-28 Becton, Dickinson And Company Detection of reticulocytes, RNA or DNA
DE3677916D1 (en) * 1985-11-01 1991-04-11 Becton Dickinson Co DETECTION OF RETICULOYCYTES.
US4957870A (en) * 1985-11-01 1990-09-18 Becton, Dickinson And Company Detection of Reticulocytes, RNA and DNA
GB8623494D0 (en) * 1986-09-30 1986-11-05 Mackay C D Assay technique
DE68924749T2 (en) * 1988-09-15 1996-07-04 The Board Of Trustees Of The University Of Arkansas, Little Rock, Ark. Identification of particles by modulated dynamic light scattering.
US5350697A (en) * 1990-08-28 1994-09-27 Akzo N.V. Scattered light detection apparatus
US7241569B2 (en) * 1993-01-18 2007-07-10 Olympus Corporation Method and a device for the evaluation of biopolymer fitness
ES2116578T3 (en) * 1993-01-18 1998-07-16 Evotec Biosystems Gmbh PROCEDURE AND DEVICE TO EVALUATE THE APTITUDE OF BIOPOLYMERS.
CA2155186A1 (en) * 1993-02-01 1994-08-18 Kevin M. Ulmer Methods and apparatus for dna sequencing
US5382512A (en) * 1993-08-23 1995-01-17 Chiron Corporation Assay device with captured particle reagent
IL113805A0 (en) * 1994-05-23 1995-08-31 Coulter Corp Detection of reticulocytes
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
CA2709217C (en) 2007-12-19 2021-01-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
AU2016218254B2 (en) 2015-02-09 2019-12-19 Slingshot Biosciences, Inc. Hydrogel particles with tunable optical properties and methods for using the same
CN106769709B (en) * 2016-12-08 2019-03-26 清华大学深圳研究生院 A kind of particulate matter method for measuring shape of palaemon and device based on polarization scattering feature
AU2021209907A1 (en) 2020-01-24 2022-07-07 Slingshot Biosciences, Inc. Compositions and methods for cell-like calibration particles
KR20240116721A (en) 2021-10-29 2024-07-30 슬링샷 바이오사이언시즈 인코포레이티드 Hydrogel particles as feeder cells and synthetic antigen-presenting cells
WO2023235885A1 (en) 2022-06-02 2023-12-07 Slingshot Biosciences, Inc. Apoptotic cell mimic
WO2024092161A2 (en) 2022-10-26 2024-05-02 Slingshot Biosciences, Inc. Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3497690A (en) * 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
US3657537A (en) * 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
US3864571A (en) * 1971-02-10 1975-02-04 Wheeler International Inc Method and Apparatus for Automatically, Identifying and Counting Various Cells in Body Fluids

Also Published As

Publication number Publication date
AU476320B2 (en) 1976-09-16
NL7407776A (en) 1975-01-06
US3872312A (en) 1975-03-18
FR2236180B1 (en) 1979-03-16
JPS5050093A (en) 1975-05-06
FR2236180A1 (en) 1975-01-31
AU6954774A (en) 1975-12-04
CH582882A5 (en) 1976-12-15
DE2431203A1 (en) 1975-01-23
GB1452231A (en) 1976-10-13

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